Peptic Ulcer
(UMLS:C0030920)
- Definition:
- Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
- UMLS ID:
- C0030920
- MeSH ID:
- D010437
Classification:
- Digestive System Diseases
- MeSH Tree Number(s):
- C06.405.469.275.800|C06.405.748.586
Synonym(s)
1.
Peptic Ulcer
2.
Gastroduodenal ulcer
3.
Gastroduodenal ulcer, NOS
4.
PEPTIC ULCER
5.
PEPTIC ULCER DISEASE
6.
PEPTIC ULCER SYNDROME
7.
PU - Peptic ulcer
8.
PUD
9.
PUD - Peptic ulcer disease
10.
Peptic Ulcer Disease
11.
Peptic ulcer
Associated Drug(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Olmesartan Medoxomil | FAERS: 105 | US FAERS | |
| 2 | Isotretinoin | FAERS: 99 | US FAERS | |
| 3 | rofecoxib | FAERS: 99 | US FAERS | |
| 4 | Alendronate | FAERS: 72 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 5 | Benicar hct | FAERS: 45 | US FAERS | |
| 6 | Omeprazole | FAERS: 25 | US FAERS | |
| 7 | Ibuprofen | FAERS: 19 Canada Vigilance: 1 | 16897817 | CTD SIDER Canada Vigilance US FAERS |
| 8 | Aspirin | FAERS: 18 Canada Vigilance: 2 | CTD SIDER Canada Vigilance US FAERS | |
| 9 | Naproxen | FAERS: 13 Canada Vigilance: 1 | 16897817 | CTD SIDER Canada Vigilance US FAERS |
| 10 | Celecoxib | FAERS: 10 Canada Vigilance: 1 | 16897817 | CTD Canada Vigilance US FAERS |
| 11 | Rivaroxaban | FAERS: 10 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 12 | Diclofenac | FAERS: 9 | 16897817 | CTD SIDER US FAERS |
| 13 | Capecitabine | FAERS: 8 | US FAERS | |
| 14 | NuvaRing | FAERS: 7 | US FAERS | |
| 15 | apixaban | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 16 | 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide | FAERS: 6 | US FAERS | |
| 17 | Clozapine | FAERS: 6 | US FAERS | |
| 18 | Sitagliptin Phosphate | FAERS: 6 | US FAERS | |
| 19 | Varenicline | FAERS: 6 | US FAERS | |
| 20 | Warfarin | FAERS: 6 | US FAERS | |
| 21 | Zoledronic Acid | FAERS: 6 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 22 | tofacitinib | FAERS: 6 | US FAERS | |
| 23 | Dabigatran | FAERS: 5 | US FAERS | |
| 24 | Erlotinib Hydrochloride | FAERS: 5 | US FAERS | |
| 25 | Esomeprazole | FAERS: 5 | US FAERS | |
| 26 | Pregabalin | FAERS: 5 | SIDER US FAERS | |
| 27 | Arthrotec | FAERS: 4 | US FAERS | |
| 28 | Chlorpheniramine | FAERS: 4 | US FAERS | |
| 29 | Clopidogrel | FAERS: 4 | US FAERS | |
| 30 | Deferasirox | FAERS: 4 | US FAERS | |
| 31 | Dimethyl Fumarate | FAERS: 4 | US FAERS | |
| 32 | Duloxetine Hydrochloride | FAERS: 4 | US FAERS | |
| 33 | Meloxicam | FAERS: 4 | SIDER US FAERS | |
| 34 | Rivastigmine | FAERS: 4 | SIDER US FAERS | |
| 35 | Tiotropium Bromide | FAERS: 4 | US FAERS | |
| 36 | ambrisentan | FAERS: 4 | US FAERS | |
| 37 | reviparin | FAERS: 4 | US FAERS | |
| 38 | Baclofen | FAERS: 3 | US FAERS | |
| 39 | Finasteride | FAERS: 3 | US FAERS | |
| 40 | Niacin | FAERS: 3 | SIDER US FAERS | |
| 41 | Ondansetron | FAERS: 3 | US FAERS | |
| 42 | Rosuvastatin Calcium | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 43 | Ruxolitinib phosphate | FAERS: 3 | US FAERS | |
| 44 | Sildenafil Citrate | FAERS: 3 | US FAERS | |
| 45 | Sorafenib | FAERS: 3 | US FAERS | |
| 46 | Tenofovir | FAERS: 3 | US FAERS | |
| 47 | Teriparatide | FAERS: 3 | US FAERS | |
| 48 | Warfarin | FAERS: 3 | US FAERS | |
| 49 | apremilast | FAERS: 3 | US FAERS | |
| 50 | teriflunomide | FAERS: 3 | US FAERS | |
| 51 | Albuterol | FAERS: 2 | US FAERS | |
| 52 | Atomoxetine Hydrochloride | FAERS: 2 | US FAERS | |
| 53 | Cinacalcet | FAERS: 2 | US FAERS | |
| 54 | Everolimus | FAERS: 2 | US FAERS | |
| 55 | Lenalidomide | FAERS: 2 | US FAERS | |
| 56 | Methylphenidate | FAERS: 2 | US FAERS | |
| 57 | Norgestrel | FAERS: 2 | US FAERS | |
| 58 | PCI 32765 | FAERS: 2 | US FAERS | |
| 59 | Prasugrel Hydrochloride | FAERS: 2 | US FAERS | |
| 60 | Simvastatin | FAERS: 2 | US FAERS | |
| 61 | Sirolimus | FAERS: 2 | US FAERS | |
| 62 | Triamcinolone Acetonide | FAERS: 2 | US FAERS | |
| 63 | deflazacort | FAERS: 2 | US FAERS | |
| 64 | etonogestrel | FAERS: 2 | US FAERS | |
| 65 | mirabegron | FAERS: 2 | US FAERS | |
| 66 | osimertinib | FAERS: 2 | US FAERS | |
| 67 | 1-N'-[2-[[5-[(Dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine;hydron;chloride | FAERS: 1 | US FAERS | |
| 68 | 4-Aminopyridine | FAERS: 1 | US FAERS | |
| 69 | Amlodipine | FAERS: 1 | US FAERS | |
| 70 | Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination | FAERS: 1 | US FAERS | |
| 71 | Atorvastatin | FAERS: 1 | US FAERS | |
| 72 | Azacitidine | FAERS: 1 | US FAERS | |
| 73 | Bimatoprost | FAERS: 1 | US FAERS | |
| 74 | Bortezomib | FAERS: 1 | US FAERS | |
| 75 | Cabergoline | FAERS: 1 | US FAERS | |
| 76 | Carbamazepine | FAERS: 1 | US FAERS | |
| 77 | Citalopram | FAERS: 1 | US FAERS | |
| 78 | Cyclophosphamide | FAERS: 1 | US FAERS | |
| 79 | Dabigatran | FAERS: 1 | US FAERS | |
| 80 | Dasatinib | FAERS: 1 | US FAERS | |
| 81 | Donepezil | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 82 | Eptifibatide | FAERS: 1 | US FAERS | |
| 83 | Erlotinib Hydrochloride | FAERS: 1 | SIDER US FAERS | |
| 84 | Etodolac | FAERS: 1 | SIDER US FAERS | |
| 85 | Fentanyl | FAERS: 1 | US FAERS | |
| 86 | Hydrochlorothiazide | FAERS: 1 | US FAERS | |
| 87 | Ibandronic Acid | FAERS: 1 | US FAERS | |
| 88 | Ibandronic Acid | FAERS: 1 | US FAERS | |
| 89 | Imatinib Mesylate | FAERS: 1 | US FAERS | |
| 90 | Insulin Glargine | FAERS: 1 | US FAERS | |
| 91 | Iopamidol | FAERS: 1 | US FAERS | |
| 92 | Lamivudine | FAERS: 1 | US FAERS | |
| 93 | Lansoprazole | FAERS: 1 | CTD US FAERS | |
| 94 | Lisdexamfetamine Dimesylate | FAERS: 1 | US FAERS | |
| 95 | Lisinopril | FAERS: 1 | US FAERS | |
| 96 | Mercaptopurine | FAERS: 1 | US FAERS | |
| 97 | Meropenem | FAERS: 1 | US FAERS | |
| 98 | Mesalamine | FAERS: 1 | US FAERS | |
| 99 | Methotrexate | FAERS: 1 | US FAERS | |
| 100 | Methylcellulose | FAERS: 1 | US FAERS | |
| 101 | Metoprolol | FAERS: 1 | US FAERS | |
| 102 | Milnacipran | FAERS: 1 | US FAERS | |
| 103 | Minocycline | FAERS: 1 | US FAERS | |
| 104 | Mirtazapine | FAERS: 1 | US FAERS | |
| 105 | Nicotine | FAERS: 1 | US FAERS | |
| 106 | Nystatin | FAERS: 1 | US FAERS | |
| 107 | Oseltamivir | FAERS: 1 | US FAERS | |
| 108 | Oxaliplatin | FAERS: 1 | US FAERS | |
| 109 | Oxycodone | FAERS: 1 | US FAERS | |
| 110 | Pamidronate | FAERS: 1 | US FAERS | |
| 111 | Pantoprazole | FAERS: 1 Canada Vigilance: 1 | 7762175 19837071 | CTD Canada Vigilance US FAERS |
| 112 | Piroxicam | FAERS: 1 Canada Vigilance: 1 | 2957207 | CTD SIDER Canada Vigilance US FAERS |
| 113 | Risperidone | FAERS: 1 | US FAERS | |
| 114 | Rosiglitazone | FAERS: 1 | US FAERS | |
| 115 | Sevelamer | FAERS: 1 | US FAERS | |
| 116 | Sulfamethoxazole | FAERS: 1 | US FAERS | |
| 117 | Sunitinib | FAERS: 1 | US FAERS | |
| 118 | Sunitinib | FAERS: 1 | US FAERS | |
| 119 | Tacrolimus | FAERS: 1 | US FAERS | |
| 120 | Thyroxine | FAERS: 1 | US FAERS | |
| 121 | Ticagrelor | FAERS: 1 | US FAERS | |
| 122 | Tramadol | FAERS: 1 | US FAERS | |
| 123 | Valproic Acid | FAERS: 1 | US FAERS | |
| 124 | Valsartan | FAERS: 1 | US FAERS | |
| 125 | Varenicline | FAERS: 1 | US FAERS | |
| 126 | acetaminophen, aspirin, caffeine drug combination | FAERS: 1 | US FAERS | |
| 127 | bupropion hydrochloride, naltrexone hydrochoride drug combination | FAERS: 1 | US FAERS | |
| 128 | gemcitabine | FAERS: 1 | US FAERS | |
| 129 | obeticholic acid | FAERS: 1 | US FAERS | |
| 130 | pimecrolimus | FAERS: 1 | US FAERS | |
| 131 | pirfenidone | FAERS: 1 | US FAERS | |
| 132 | ropinirole | FAERS: 1 | SIDER US FAERS | |
| 133 | sapropterin | FAERS: 1 | US FAERS | |
| 134 | tegaserod | FAERS: 1 | US FAERS | |
| 135 | zafirlukast | FAERS: 1 | US FAERS | |
| 136 | Acetic Acid | 31095933 | CTD | |
| 137 | Albuterol | Canada Vigilance: 1 | Canada Vigilance | |
| 138 | Amiloride | SIDER | ||
| 139 | Amoxicillin | 11841141 | CTD | |
| 140 | Aripiprazole | SIDER | ||
| 141 | Atazanavir Sulfate | SIDER | ||
| 142 | Atropine | 7034155 | CTD | |
| 143 | Bisoprolol | SIDER | ||
| 144 | Bromocriptine | SIDER | ||
| 145 | Caffeine | Canada Vigilance: 1 | Canada Vigilance | |
| 146 | Calcium Carbonate | 3532984 | CTD | |
| 147 | Calcium Compounds | 8667442 | CTD | |
| 148 | Captopril | SIDER | ||
| 149 | Cefdinir | SIDER | ||
| 150 | Choline | SIDER | ||
| 151 | Cilostazol | SIDER | ||
| 152 | Cimetidine | Canada Vigilance: 1 |
21785
81467 434259 509014 762851 2360334 2773966 3283917 3777737 6145972 6835285 7034155 7205315 7272161 7435686 7463626 11421865 15955208 17189874 | CTD Canada Vigilance |
| 153 | Clarithromycin | CTD | ||
| 154 | Clomipramine | SIDER | ||
| 155 | Clopidogrel | SIDER | ||
| 156 | Colestipol | SIDER | ||
| 157 | Cortisone | SIDER | ||
| 158 | Dexamethasone | SIDER | ||
| 159 | Diflunisal | SIDER | ||
| 160 | Dipyridamole | SIDER | ||
| 161 | Etidronic Acid | SIDER | ||
| 162 | Etoricoxib | SIDER | ||
| 163 | Famotidine | CTD | ||
| 164 | Febuxostat | SIDER | ||
| 165 | Fenofibrate | SIDER | ||
| 166 | Fenoprofen | SIDER | ||
| 167 | Fludrocortisone | SIDER | ||
| 168 | Fluoxetine | SIDER | ||
| 169 | Flurbiprofen | Canada Vigilance: 1 | Canada Vigilance SIDER | |
| 170 | Gabapentin | SIDER | ||
| 171 | Halcinonide | SIDER | ||
| 172 | Hesperidin | 31095933 | CTD | |
| 173 | Hydrochloric Acid | 15236176 | CTD | |
| 174 | Hydrocortisone | SIDER | ||
| 175 | Indomethacin | CTD SIDER | ||
| 176 | Ketoprofen | 15322343 | CTD SIDER | |
| 177 | Ketorolac | SIDER | ||
| 178 | Lamotrigine | SIDER | ||
| 179 | Leuprolide | SIDER | ||
| 180 | Lincomycin | Canada Vigilance: 1 | Canada Vigilance | |
| 181 | Methylprednisolone | SIDER | ||
| 182 | Metiamide | 21785 | CTD | |
| 183 | Metoclopramide | 7205315 | CTD | |
| 184 | Metronidazole | 9570262 | CTD | |
| 185 | Mexiletine | SIDER | ||
| 186 | Misoprostol | 9637807 21650226 | CTD | |
| 187 | Mycophenolic Acid | SIDER | ||
| 188 | Nabumetone | SIDER | ||
| 189 | Naproxen | Canada Vigilance: 1 | Canada Vigilance | |
| 190 | Octreotide | SIDER | ||
| 191 | Omeprazole | Canada Vigilance: 1 | CTD Canada Vigilance | |
| 192 | Oxandrolone | 5569832 | CTD | |
| 193 | Oxaprozin | SIDER | ||
| 194 | Paroxetine | SIDER | ||
| 195 | Penicillamine | SIDER | ||
| 196 | Pergolide | SIDER | ||
| 197 | Phentolamine | SIDER | ||
| 198 | Phenylbutazone | Canada Vigilance: 1 | 3764320 7744695 | CTD Canada Vigilance |
| 199 | Pirenzepine | 12046381 | CTD | |
| 200 | Prednisolone | SIDER | ||
| 201 | Prednisone | SIDER | ||
| 202 | Propafenone | SIDER | ||
| 203 | Propranolol | Canada Vigilance: 1 | Canada Vigilance | |
| 204 | Pyrazinamide | SIDER | ||
| 205 | Raltegravir Potassium | SIDER | ||
| 206 | Ranitidine | CTD | ||
| 207 | Ribavirin | SIDER | ||
| 208 | Selegiline | SIDER | ||
| 209 | Sertraline | SIDER | ||
| 210 | Spironolactone | 5569832 | CTD | |
| 211 | Sulindac | SIDER | ||
| 212 | Sumatriptan | SIDER | ||
| 213 | Theophylline | SIDER | ||
| 214 | Ticlopidine | SIDER | ||
| 215 | Tinidazole | 11394734 | CTD | |
| 216 | Travoprost | SIDER | ||
| 217 | Triamcinolone | SIDER | ||
| 218 | Vinblastine | SIDER | ||
| 219 | Zonisamide | SIDER | ||
| 220 | aluminum hydroxide, magnesium hydroxide, drug combination | 434259 | CTD | |
| 221 | benoxaprofen | 7084281 | CTD | |
| 222 | bismuth subsalicylate | 10422349 | CTD | |
| 223 | cevimeline | SIDER | ||
| 224 | dienogest | Canada Vigilance: 1 | Canada Vigilance | |
| 225 | frovatriptan | SIDER | ||
| 226 | lercanidipine | SIDER | ||
| 227 | nefazodone | SIDER | ||
| 228 | ranitidine bismuth citrate | 11394734 | CTD | |
| 229 | roxatidine acetate | 20586863 21805066 | CTD | |
| 230 | sitaxsentan | SIDER | ||
| 231 | tenoxicam | SIDER | ||
| 232 | tetraethylenepentamine | SIDER | ||
| 233 | zaleplon | SIDER |
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