MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Brain Diseases, Metabolic

(UMLS:C0006112)

Definition:: Acquired or inborn metabolic diseases that produce brain dysfunction or damage. These include primary (i.e., disorders intrinsic to the brain) and secondary (i.e., extracranial) metabolic conditions that adversely affect cerebral function.
UMLS ID:: C0006112
MeSH ID:: D001928

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.163

Classification 2:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.132

Synonym(s)

Brain Diseases, Metabolic

ENCEPHALOPATHY METABOLIC

Metabolic Encephalopathy

Metabolic brain syndrome

Metabolic brain syndrome, NOS

Metabolic encephalopathy

encephalopathy metabolic

metabolic brain diseases

metabolic disorders brain

10.

metabolic encephalopathy

Associated Drug(s)

	Name	Reference(s)	Data Source
1	5-Methoxytryptamine	18062943	CTD
2	Ammonia	17661800	CTD
3	Amoxapine	3281327	CTD
4	Aspirin	712501	CTD
5	Bezafibrate	21816645	CTD
6	Chlorpropamide	879949	CTD
7	Cyclosporine	10410193	CTD
8	Deferoxamine	4095247	CTD
9	Diltiazem	10410193	CTD
10	Methylprednisolone	7618796	CTD
11	Oxcarbazepine	1949275	CTD
12	Phenformin	879949	CTD
13	Prochlorperazine	4095247	CTD
14	Streptozocin	18515212	CTD
15	Tacrolimus	15919502	CTD
16	Tolbutamide	879949	CTD
17	Topiramate	16010067	CTD
18	Valproic Acid	View details 1906442 6419536 9598692 9700838 10846716 10897167 12199737 15266186 15528922 15647953 16010067 16908754 17412645 17661800 17846437 18333544 18446695 18806245 19133574 19304858 20337505	CTD
19	Vitamin B 12	6965256 7270059	CTD
20	Vitamin D	8190198	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Posterior Leukoencephalopathy Syndrome	32%
2	Posterior reversible encephalopathy syndrome	32%
3	Akinetic Mutism	31.8%
4	Anoxic Encephalopathy	31.8%
5	Basal Ganglia Diseases	31.8%
6	Brain Damage, Chronic	31.8%
7	Cerebellar Diseases	31.8%
8	Encephalitis	31.8%
9	Encephalomalacia	31.8%
10	Epilepsy	31.8%
11	Hydrocephalus	31.8%
12	Congenital Hydrocephalus	31.8%
13	Hypothalamic Diseases	31.8%
14	Thalamic Diseases	31.8%
15	Intracranial Hypertension	31.8%
16	Aura	31.8%
17	Leukoencephalopathy	31.8%
18	Neuroaxonal Dystrophies	31.8%
19	Headache Disorders	31.8%
20	Intracranial Hypotension	31.8%
21	Brain Edema	31.8%
22	Brain Hypoxia	31.8%
23	Aqueductal Stenosis	31.8%
24	Subdural Effusion	31.1%
25	Hypercalcemia	30.5%
26	Hypocalcemia	30.5%
27	Milk-Alkali Syndrome	30.5%
28	Meningoencephalitis	30%
29	Myoclonic Epilepsy	28.9%
30	Epilepsy, Temporal Lobe	28.9%
31	Epilepsy, Rolandic	28.9%
32	Benign Rolandic Epilepsy	28.9%
33	Dementia, Vascular	28.6%
34	Wasting Syndrome	28.1%
35	Basal Ganglia Cerebrovascular Disease	28%
36	Acid-Base Imbalance	27.9%
37	Calcium Metabolism Disorders	27.9%
38	Iron Metabolism Disorders	27.9%
39	Phosphorus Metabolism Disorders	27.9%
40	Water-Electrolyte Imbalance	27.9%
41	Lipid Metabolism Disorders	27.9%
42	Mitochondrial Diseases	27.9%
43	Glucose Metabolism Disorders	27.9%
44	Parkinsonian Disorders	27.7%
45	Dandy-Walker Syndrome	27%
46	Juvenile Myoclonic Epilepsy	25.9%
47	Myoclonic Epilepsies, Progressive	25.9%
48	Encephalomyelitis	25.9%
49	Vascular Headaches	25.6%
50	Lewy Body Disease	25.5%
51	Hypoxia-Ischemia, Brain	25.4%
52	Meige Syndrome	25%
53	Cerebral Ventriculitis	25%
54	Epilepsy, Post-Traumatic	24.7%
55	Lipodystrophy	24.3%
56	Multiple System Atrophy	24.3%
57	Pseudohypoparathyroidism	24.3%
58	Cerebrovascular Disorders	24.1%
59	Cerebrovascular Insufficiency	24.1%
60	Dementia	24.1%
61	Cerebral Palsy	23.6%
62	Epilepsies, Partial	23.6%
63	Epilepsy, Generalized	23.6%
64	Pseudotumor Cerebri	23.6%
65	Hypertensive Encephalopathy	23.6%
66	Simple Partial Seizures	23.6%
67	Epilepsy, Reflex	23.6%
68	Headache Disorders, Primary	23.6%
69	Headache Disorders, Secondary	23.6%
70	Medication overuse headache	23.6%
71	Pneumocephalus	23.5%
72	Leukomalacia, Periventricular	23.3%
73	Brain Abscess	22.6%
74	Rickets	22.4%
75	Friedreich Ataxia	22.4%
76	Cerebellar Neoplasms	22.3%
77	Hyperlipoproteinemia Type IV	22.1%
78	Hyperlipoproteinemia Type V	22.1%
79	Parkinson Disease	21.9%
80	Brain Injuries	21.6%
81	Brain Neoplasms	21.5%
82	Osteopenia	21.1%
83	Meningitis	20.9%
84	Movement Disorders	20.9%
85	Pachymeningitis	20.9%
86	Spinal Cord Diseases	20.9%
87	Basal Ganglia Hemorrhage	20.6%
88	Hyperhomocysteinemia	20.5%
89	Acidosis	20.5%
90	Alkalosis	20.5%
91	Amyloidosis	20.5%
92	Calcinosis	20.5%
93	Hyperglycemia	20.5%
94	Hyperinsulinism	20.5%
95	Hyperkalemia	20.5%
96	Hypernatremia	20.5%
97	Hypoglycemia	20.5%
98	Hypokalemia	20.5%
99	Hyponatremia	20.5%
100	Xanthomatosis	20.5%
101	Hypophosphatemia	20.5%
102	Metabolic acidosis	20.5%
103	Dyslipidemias	20.5%
104	Iron Overload	20.5%
105	Xanthoma	20.5%
106	Myelitis	20.3%
107	Brain Death	20.2%
108	Cerebral Amyloid Angiopathy	20.2%
109	Creutzfeldt-Jakob disease	20%
110	Hypolipoproteinemias	19.9%
111	Huntington Disease	19.7%
112	Post-Traumatic Headache	19.6%
113	Tension Headache	19.6%
114	Epilepsy, Complex Partial	19.6%
115	Migraine Disorders	19.6%
116	Abdominal Migraine	19.6%
117	Status Migrainosus	19.6%
118	Cervicogenic Headache	19.6%
119	Familial Hypophosphatemic Rickets	19.5%
120	Pituitary Apoplexy	19.4%
121	Brain Infarction	19.1%
122	Diabetic Ketoacidosis	18.9%
123	Dystonia Musculorum Deformans	18.9%
124	Hyperlipidemia, Familial Combined	18.8%
125	Putaminal Hemorrhage	18.7%
126	Amyotrophic Lateral Sclerosis	18.7%
127	Osteomalacia	18.7%
128	Pituitary Diseases	18.6%
129	Frontotemporal dementia	18.6%
130	Lafora Disease	18.6%
131	Unverricht-Lundborg Syndrome	18.6%
132	Smith-Lemli-Opitz Syndrome	18.5%
133	Striatonigral Degeneration	18.5%
134	Neuroleptic Malignant Syndrome	18.4%
135	Epidural Abscess	18.3%
136	Infarction, Middle Cerebral Artery	18.3%
137	Infarction, Anterior Cerebral Artery	18.3%
138	Infarction, Posterior Cerebral Artery	18.3%
139	Hyperlipoproteinemia Type III	18.3%
140	Lactose Intolerance	18.2%
141	Amyloid Neuropathies, Familial	17.9%
142	Hypoalphalipoproteinemias	17.7%
143	Carotid Artery Diseases	17.6%
144	Brain Ischemia	17.6%
145	Cerebrovascular accident	17.6%
146	Kluver-Bucy Syndrome	17.6%
147	Vasospasm, Intracranial	17.6%
148	Intracranial Arterial Diseases	17.6%
149	Leukoencephalopathy, Progressive Multifocal	17.6%
150	Cluster Headache	17.5%
151	Migraine with Aura	17.5%
152	Familial Hemiplegic Migraine	17.5%
153	Chronic Paroxysmal Hemicrania	17.5%
154	SUNCT Syndrome	17.5%
155	Paroxysmal Hemicrania	17.5%
156	Pituitary Adenoma	17.5%
157	Pituitary Neoplasms	17.5%
158	Ocular Motility Disorders	17.4%
159	Cyclophoria	17.4%
160	Amblyopia	17.4%
161	Cerebral Infarction	17.1%
162	Brain Stem Infarctions	17.1%
163	Congenital Hyperinsulinism	17%
164	Hepatolenticular Degeneration	17%
165	Leigh Disease	16.9%
166	Acidosis, Lactic	16.9%
167	Calciphylaxis	16.9%
168	Hemosiderosis	16.9%
169	Ketosis	16.9%
170	Ketonuria	16.9%
171	Ketoacidosis	16.9%
172	Ketonemia	16.9%
173	Vascular calcification	16.9%
174	Presenile dementia	16.8%
175	Senile dementia	16.8%
176	Central Nervous System Infection	16.4%
177	Hyperphosphaturia	16.3%
178	MPTP Poisoning	16.3%
179	Carbamoyl-Phosphate Synthase I Deficiency Disease	16.2%
180	Lupus Vasculitis, Central Nervous System	16.2%
181	Limbic Encephalitis	16.1%
182	Diabetes Mellitus	16.1%
183	Lateral Medullary Syndrome	16.1%
184	Carotid Artery Injuries	16%
185	Brain Injuries, Diffuse	15.9%
186	Traumatic Brain Injury	15.9%
187	Fabry Disease	15.9%
188	Cerebellar Ataxia	15.8%
189	Supratentorial Neoplasms	15.8%
190	Shy-Drager Syndrome	15.8%
191	Ataxia Telangiectasia	15.8%
192	Progressive supranuclear palsy	15.8%
193	Moyamoya Disease	15.6%
194	Dehydration	15.5%
195	Lipomatosis	15.5%
196	Water Intoxication	15.5%
197	Werner Syndrome	15.5%
198	Prion Diseases	15.5%
199	Brain Hemorrhage, Traumatic	15.5%
200	Leukoencephalitis, Acute Hemorrhagic	15.5%
201	Persistent Vegetative State	15.4%
202	Neuronal Ceroid-Lipofuscinoses	15.3%
203	Achlorhydria	15.3%
204	Amino Acid Metabolism, Inborn Errors	15.3%
205	Bloom Syndrome	15.3%
206	Carbohydrate Metabolism, Inborn Errors	15.3%
207	Metal Metabolism, Inborn Errors	15.3%
208	Osteoporosis	15.3%
209	Progeria	15.3%
210	Lysosomal Storage Diseases	15.3%
211	Bone Demineralization, Pathologic	15.3%
212	Cytochrome-c Oxidase Deficiency	15.3%
213	Peroxisomal Disorders	15.3%
214	Post-Traumatic Osteoporosis	15.3%
215	Celiac Disease	15.1%
216	Sprue, Tropical	15.1%
217	Steatorrhea	15.1%
218	Sprue	15.1%
219	Hypercholesterolemia	15.1%
220	Hyperlipoproteinemias	15.1%
221	Hypertriglyceridemia	15.1%
222	Mitochondrial Myopathies	15.1%
223	Gaucher Disease	15.1%
224	Nesidioblastosis	14.9%
225	Empty Sella Syndrome	14.9%
226	Hyperpituitarism	14.9%
227	Hypopituitarism	14.9%
228	Hypophysitis	14.9%
229	Nutrition Disorders	14.6%
230	Cerebral Arterial Diseases	14.5%
231	Vertebrobasilar Insufficiency	14.5%
232	Basilar Artery Stenosis	14.5%
233	Vertebral Artery Stenosis	14.5%
234	Intracranial Hemorrhage, Hypertensive	14.5%
235	Transient Cerebral Ischemia	14.5%
236	Amnesia, Transient Global	14.4%
237	MELAS Syndrome	14.3%
238	Tay-Sachs Disease	14.2%
239	Encephalomyelitis, Acute Disseminated	14.1%
240	Meningitis, Bacterial	14.1%
241	Meningitis, Fungal	14.1%
242	Renal tubular acidosis	14.1%
243	Intracranial Embolism and Thrombosis	14%
244	Paraneoplastic Cerebellar Degeneration	13.9%
245	Stiff-Person Syndrome	13.8%
246	Toxoplasmosis, Cerebral	13.7%
247	Subacute Combined Degeneration	13.7%
248	Arachnoiditis	13.6%
249	Aseptic Meningitis	13.6%
250	Syringomyelia	13.6%
251	Essential Tremor	13.6%
252	Familial Tremor	13.6%
253	Pneumorrhachis	13.6%
254	Writer's Cramp	13.6%
255	Spinal Muscular Atrophy	13.5%
256	Progressive Muscular Atrophy	13.5%
257	Poliomyelitis	13.4%
258	Niemann-Pick Disease, Type C	13.3%
259	Hyperprolactinemia	13.2%
260	Diffuse Axonal Injury	13.1%
261	Brain Stem Neoplasms	13.1%
262	Glycogen storage disease type II	13.1%
263	Vasculitis, Central Nervous System	13%
264	Subclavian Steal Syndrome	13%
265	Pick Disease of the Brain	13%
266	Spinal Cord Injuries	12.9%
267	Canavan Disease	12.8%
268	Alexander Disease	12.8%
269	Tetany	12.7%
270	Acidosis, Respiratory	12.6%
271	Adiposis Dolorosa	12.6%
272	Alkalosis, Respiratory	12.6%
273	Mucopolysaccharidosis III	12.6%
274	Ophthalmoplegic Migraine	12.5%
275	Alkaptonuria	12.5%
276	Glycogen Storage Disease	12.5%
277	Hypophosphatasia	12.5%
278	Insulin Resistance	12.5%
279	Osteoporosis, Postmenopausal	12.5%
280	Propionic acidemia	12.5%
281	Dihydropyrimidine Dehydrogenase Deficiency	12.5%
282	Cystinosis	12.5%
283	Subarachnoid Hemorrhage, Traumatic	12.4%
284	Carotid Artery, Internal, Dissection	12.4%
285	Renal Osteodystrophy	12.4%
286	Renal rickets	12.4%
287	Asterixis	12.3%
288	Ballismus	12.3%
289	HIV-Associated Lipodystrophy Syndrome	12.3%
290	Galactosemias	12.3%
291	Urea Cycle Disorders, Inborn	12.3%
292	Tyrosinemias	12.3%
293	Cranial nerve diseases	12.2%
294	Demyelinating Diseases	12.2%
295	Demyelination	12.2%
296	Neuromuscular Diseases	12.2%
297	Chronobiology Disorders	12.2%
298	Adrenoleukodystrophy	12.1%
299	Glycosuria	12.1%
300	Miller Fisher Syndrome	12%
301	Choroid Plexus Papilloma	11.7%
302	Carotid Stenosis	11.6%
303	Intracranial Aneurysm	11.6%
304	Intracranial Arteriosclerosis	11.6%
305	Cerebral Atherosclerosis	11.6%
306	Subarachnoid Hemorrhage	11.6%
307	Cerebral Arteriosclerosis	11.6%
308	Cerebral Hemorrhage	11.6%
309	Cerebral Thrombosis	11.5%
310	Intracranial Embolism	11.5%
311	Intracranial Thrombosis	11.5%
312	HIV Wasting Syndrome	11.4%
313	Subacute Sclerosing Panencephalitis	11.4%
314	Tuberculosis, Meningeal	11.2%
315	Glycogen Storage Disease Type I	11.2%
316	Glycogen Storage Disease Type V	11.2%
317	Brain Contusion	11%
318	Glycosuria, Renal	10.9%
319	Spinal Cord Neoplasms	10.7%
320	Chronic Fatigue Syndrome	10.7%
321	Familial Periodic Paralysis	10.7%
322	Kearns-Sayre syndrome	10.6%
323	Motor Neuron Disease	10.5%
324	Acromegaly	10.5%
325	Homocystinuria	10.4%
326	Gestational Diabetes	10.3%
327	Central Nervous System Fungal Infections	10.3%
328	Conus Medullaris Syndrome	10.3%
329	Spinal Cord Vascular Diseases	10.3%
330	Latent Autoimmune Diabetes in Adults	10.3%
331	Sinus Thrombosis, Intracranial	10.3%
332	Porphyrias, Hepatic	10.2%
333	Diabetes Mellitus, Experimental	10.2%
334	Vertebral Artery Dissection	10.2%
335	Necrobiosis Lipoidica Diabeticorum	10.1%
336	Brain Diseases, Metabolic, Inborn	10.1%
337	Nephrocalcinosis	10%
338	Fanconi Anemia	9.9%
339	Myelitis, Transverse	9.9%
340	AIDS Dementia Complex	9.9%
341	Refsum Disease	9.9%
342	Auditory Perceptual Disorders	9.9%
343	Cavernous Sinus Thrombosis	9.7%
344	Sagittal Sinus Thrombosis	9.7%
345	Carotid Artery Thrombosis	9.6%
346	Mucopolysaccharidosis II	9.6%
347	Trauma, Nervous System	9.4%
348	Brain Concussion	9.4%
349	Child Nutrition Disorders	9.3%
350	Hypervitaminosis A	9.3%
351	Infant Nutrition Disorders	9.3%
352	Malnutrition	9.3%
353	West Nile Fever	9.3%
354	Cockayne Syndrome	9.2%
355	Nervous System Neoplasms	9.1%
356	Neurologic Manifestations	9.1%
357	Meningitis, Cryptococcal	9.1%
358	Neurotoxicity Syndromes	9.1%
359	Hypokalemic periodic paralysis	9.1%
360	Meningitis, Listeria	9%
361	Meningitis, Haemophilus	9%
362	Meningitis, Pneumococcal	9%
363	Alice in Wonderland Syndrome	8.9%
364	Scrapie	8.8%
365	Central Cord Syndrome	8.8%
366	Menkes Kinky Hair Syndrome	8.8%
367	Akathisia, Drug-Induced	8.8%
368	Chorea	8.7%
369	Autonomic Dysreflexia	8.6%
370	Complex Regional Pain Syndromes	8.6%
371	Optic Atrophy, Hereditary, Leber	8.6%
372	Opsoclonus-Myoclonus Syndrome	8.6%
373	Polyradiculoneuropathy	8.6%
374	Polyradiculoneuritis	8.6%
375	Mitochondrial Encephalomyopathies	8.5%
376	Sjogren-Larsson Syndrome	8.5%
377	Primary amyloidosis	8.4%
378	Restless Legs Syndrome	8.3%
379	Central Nervous System Bacterial Infections	8.3%
380	Variegate Porphyria	8.3%
381	Acute intermittent porphyria	8.3%
382	Porphyria Cutanea Tarda	8.3%
383	Zellweger Syndrome	8.3%
384	Renal Aminoacidurias	8.2%
385	Fanconi Syndrome	8.2%
386	Pseudohypoaldosteronism	8.2%
387	Liddle Syndrome	8.2%
388	Nelson Syndrome	8.1%
389	Dyskinesia, Drug-Induced	8.1%
390	Torticollis	7.9%
391	Giant Cell Arteritis	7.9%
392	Temporal Arteritis	7.9%
393	Hematoma, Subdural	7.6%
394	Hematoma, Epidural, Cranial	7.6%
395	Spinal Cord Ischemia	7.6%
396	Tuberculosis, Central Nervous System	7.5%
397	Prolactinoma	7.4%
398	Growth Hormone-Secreting Pituitary Adenoma	7.4%
399	Sleep Wake Disorders	7.4%
400	Cystinuria	7.3%
401	Gout	7.2%
402	Antley-Bixler Syndrome Phenotype	7.1%
403	Hematoma, Subdural, Intracranial	7%
404	Hematoma, Subdural, Chronic	7%
405	Hematoma, Subdural, Acute	7%
406	Dysautonomia	7%
407	Vagus Nerve Disorder	7%
408	Glossopharyngeal Neuralgia	7%
409	Abducens Nerve Diseases	7%
410	Heavy Metal Poisoning, Nervous System	7%
411	Neuromuscular Junction Diseases	7%
412	Tauopathies	7%
413	Trochlear Nerve Diseases	7%
414	Peripheral Nervous System Diseases	7%
415	Peripheral Nerve Injuries	6.9%
416	Tardive Dyskinesia	6.9%
417	Guillain-Barre Syndrome	6.9%
418	Myasthenia Gravis	6.8%
419	Deficiency Diseases	6.8%
420	Starvation	6.8%
421	Refeeding Syndrome	6.8%
422	Progressive bulbar palsy	6.8%
423	Bulbar palsy	6.8%
424	Causalgia	6.7%
425	Arthritis, Gouty	6.3%
426	Anterior Spinal Artery Syndrome	6.2%
427	CREST Syndrome	6.2%
428	Olfactory Nerve Injuries	6.1%
429	Xeroderma Pigmentosum	6.1%
430	Neuroaspergillosis	6%
431	Lambert-Eaton Myasthenic Syndrome	5.9%
432	Reflex Sympathetic Dystrophy	5.9%
433	Nocturnal Myoclonus Syndrome	5.9%
434	Sleep Disorders, Circadian Rhythm	5.9%
435	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	5.8%
436	Botulism	5.6%
437	Central Nervous System Cysts	5.6%
438	Kwashiorkor	5.6%
439	Magnesium Deficiency	5.6%
440	Potassium Deficiency	5.6%
441	Protein Deficiency	5.6%
442	Avitaminosis	5.6%
443	Neuromyelitis Optica	5.6%
444	Albinism	5.6%
445	Myopathy	5.5%
446	Optic Neuropathy	5.5%
447	Multiple Sclerosis	5.4%
448	Facial Nerve Diseases	5.3%
449	Craniocerebral Trauma	5.3%
450	Parasomnia	5.3%
451	Pseudorabies	5.3%
452	Dyssomnias	5.3%
453	Facial Nerve Injuries	5.2%
454	Vestibulocochlear Nerve Diseases	5.2%
455	Decerebrate State	5.2%
456	Hemiparesis	5.2%
457	Hydranencephaly	5.2%
458	Meningism	5.2%
459	Neural Tube Defects	5.2%
460	Paresis	5.2%
461	Seizures	5.2%
462	Sensation Disorders	5.2%
463	Tethered Cord Syndrome	5.2%
464	Central Nervous System Neoplasms	5.2%
465	Complex partial seizures	5.2%
466	Iniencephaly	5.2%
467	Craniorachischisis	5.2%
468	Exencephaly	5.2%
469	Monoparesis	5.2%
470	Septo-Optic Dysplasia	5.2%
471	Cortical Dysplasia	5.2%
472	Neurogenic Inflammation	5.2%
473	Gait Disorders, Neurologic	5.2%
474	Neuromuscular Manifestations	5.2%
475	Malformations of Cortical Development	5.2%
476	Sweating, Gustatory	5.1%
477	Auriculotemporal Syndrome	5.1%
478	Marchiafava-Bignami Disease	5.1%
479	Toxoplasmosis, Congenital	5.1%
480	Horner Syndrome	5%
481	Ascorbic Acid Deficiency	5%
482	Vitamin A Deficiency	5%
483	Vitamin D Deficiency	5%
484	Vitamin E Deficiency	5%
485	Marasmus	5%
486	Malaria, Cerebral	5%
487	Brachial Plexus Neuritis	5%
488	Neuralgic Amyotrophy	5%
489	Neurocysticercosis	5%
490	Neurosyphilis	4.9%
491	Folic Acid Deficiency	4.7%
492	Pellagra	4.7%
493	Thiamine Deficiency	4.7%
494	Vitamin B 12 Deficiency	4.7%
495	Vitamin B 6 Deficiency	4.7%
496	Pyridoxine Deficiency	4.7%
497	Acrodynia	4.7%
498	Beriberi	4.6%
499	Tarsal Tunnel Syndrome	4.6%
500	Cauda Equina Syndrome	4.6%
501	Neuritis	4.5%
502	Polyneuritis	4.5%
503	Radiculitis	4.5%
504	Polyneuropathy	4.5%
505	Mononeuritis	4.5%
506	Mononeuropathies	4.5%
507	Brachial Plexus Neuropathies	4.5%
508	Radiculopathy	4.5%
509	Mononeuropathy Multiplex	4.5%
510	Nerve Root Compression	4.5%
511	Myasthenia Gravis, Autoimmune, Experimental	4.5%
512	Ophthalmoplegia	4.5%
513	External Ophthalmoplegia	4.5%
514	Ichthyosis, X-Linked	4.5%
515	Charcot-Marie-Tooth Disease	4.5%
516	Jet Lag Syndrome	4.3%
517	Pupil Disorders	4.3%
518	Neurobehavioral Manifestations	4.3%
519	Waterhouse-Friderichsen Syndrome	4.2%
520	Lyme Neuroborreliosis	4.2%
521	Coma, Post-Head Injury	4.2%
522	Paraneoplastic Encephalomyelitis	4.2%
523	Uveomeningoencephalitic Syndrome	4.1%
524	Sturge-Weber Syndrome	4.1%
525	Vertigo	4.1%
526	Myelinolysis, Central Pontine	4.1%
527	Alcohol-Induced Disorders, Nervous System	4.1%
528	Tuberous Sclerosis	4%
529	Multiple Sclerosis, Chronic Progressive	4%
530	Multiple Sclerosis, Relapsing-Remitting	4%
531	Myotonia Congenita	3.9%
532	Vocal Cord Paralysis	3.9%
533	Cerebrospinal Fluid Otorrhea	3.9%
534	Cerebrospinal Fluid Rhinorrhea	3.9%
535	Neuritis, Autoimmune, Experimental	3.9%
536	Gait Ataxia	3.9%
537	Prader-Willi Syndrome	3.8%
538	Carpal Tunnel Syndrome	3.7%
539	neurofibroma	3.6%
540	Sciatica	3.6%
541	Myotonic Dystrophy	3.5%
542	Voice Disorders	3.5%
543	Voice Disturbance	3.5%
544	Myositis	3.4%
545	Optic Atrophy	3.4%
546	Optic Neuritis	3.4%
547	Papilledema	3.4%
548	Strabismus	3.4%
549	Tolosa-Hunt Syndrome	3.4%
550	Isaacs syndrome	3.4%
551	Arsenic Poisoning	3.4%
552	Myotonic Disorders	3.4%
553	Myasthenic Syndromes, Congenital	3.4%
554	Smith-Magenis syndrome	3.4%
555	Anemia, Pernicious	3.4%
556	Diabetic Neuropathies	3.4%
557	Facial Injuries	3.4%
558	Facial Neuralgia	3.4%
559	Diabetic Amyotrophy	3.4%
560	Diabetic Autonomic Neuropathy	3.4%
561	Sleep Talking	3.4%
562	Manganese Poisoning	3.4%
563	Dural Arteriovenous Fistula	3.4%
564	Sleep Disorders, Intrinsic	3.4%
565	Orthostatic intolerance	3.4%
566	Sciatic Neuropathy	3.4%
567	Ulnar Neuropathies	3.4%
568	Lesion of Sciatic Nerve	3.4%
569	Ulnar Neuritis	3.4%
570	Radial nerve compression	3.4%
571	Radial Tunnel Syndrome	3.4%
572	Peroneal Neuropathies	3.4%
573	Radial Neuropathy	3.4%
574	Median Neuropathy	3.4%
575	Sciatic Nerve Palsy	3.4%
576	Femoral Neuropathy	3.4%
577	Tibial Neuropathy	3.4%
578	Ulnar Nerve Palsy	3.4%
579	Postural Orthostatic Tachycardia Syndrome	3.4%
580	Radial nerve palsy	3.4%
581	Anosmia	3.4%
582	Ataxia	3.4%
583	Athetosis	3.4%
584	Catalepsy	3.4%
585	Dystonia	3.4%
586	Hemiplegia	3.4%
587	Locked-In Syndrome	3.4%
588	Meningeal Neoplasms	3.4%
589	Meningomyelocele	3.4%
590	Muscle Hypertonia	3.4%
591	Muscle hypotonia	3.4%
592	Myoclonus	3.4%
593	Myotonia	3.4%
594	Neuralgia	3.4%
595	Paraplegia	3.4%
596	Pseudobulbar Palsy	3.4%
597	Quadriplegia	3.4%
598	Spasm	3.4%
599	Spastic Paraplegia	3.4%
600	Status Epilepticus	3.4%
601	Taste Disorders	3.4%
602	Tremor	3.4%
603	Spina Bifida	3.4%
604	Monoplegia	3.4%
605	Hypokinesia	3.4%
606	Paraparesis	3.4%
607	Bradykinesia	3.4%
608	Waxy flexibility	3.4%
609	Action Tremor	3.4%
610	Resting Tremor	3.4%
611	Dysosmia	3.4%
612	Quadriparesis	3.4%
613	Mercury Poisoning, Nervous System	3.4%
614	Olfaction Disorders	3.4%
615	Myokymia	3.4%
616	Lead Poisoning, Nervous System	3.4%
617	Vestibular Neuronitis	3.4%
618	Somatosensory Disorders	3.4%
619	Neuropathic pain	3.4%
620	Hyperkinesia	3.4%
621	Intention tremor	3.4%
622	Alcohol Withdrawal Seizures	3.3%
623	Akathisia	3.3%
624	Restlessness	3.3%
625	Psychomotor Agitation	3.3%
626	Cubital Tunnel Syndrome	3.3%
627	Obesity	3.3%
628	Obesity, Abdominal	3.3%
629	Optic Nerve Glioma	3.1%
630	Gait Apraxia	3%
631	Vitamin K Deficiency	3%
632	Reflex, Abnormal	2.9%
633	Hyporeflexia	2.9%
634	Hyperreflexia	2.9%
635	Hand-Arm Vibration Syndrome	2.9%
636	Alstrom Syndrome	2.8%
637	Scurvy	2.8%
638	Vision Disorders	2.8%
639	Metamorphopsia	2.8%
640	Visual Impairment	2.8%
641	Polyradiculopathy	2.8%
642	Fibromyalgia	2.8%
643	Optic Neuropathy, Ischemic	2.8%
644	Anterior Ischemic Optic Neuropathy	2.8%
645	Medial Tibial Stress Syndrome	2.8%
646	Facial Hemiatrophy	2.7%
647	Melkersson-Rosenthal Syndrome	2.7%
648	Anisocoria	2.7%
649	Confusion	2.7%
650	Facial paralysis	2.7%
651	Lethargy	2.7%
652	Memory Disorders	2.7%
653	Muscle Cramp	2.7%
654	Perceptual Disorders	2.7%
655	Psychomotor Disorders	2.7%
656	Tonic Pupil	2.7%
657	Eosinophilia-Myalgia Syndrome	2.7%
658	Anhedonia	2.7%
659	Disorientation	2.7%
660	Facial Paresis	2.7%
661	Memory Loss	2.7%
662	Hemisensory Neglect	2.7%
663	Dysacusis	2.7%
664	Pediatric Obesity	2.7%
665	Sleep Bruxism	2.7%
666	Anencephaly	2.7%
667	Meningocele	2.7%
668	Muscular Atrophy	2.7%
669	Respiratory Paralysis	2.7%
670	Encephalocele	2.7%
671	Thoracic Outlet Syndrome	2.6%
672	Classical Lissencephalies and Subcortical Band Heterotopias	2.6%
673	Esotropia	2.5%
674	Exotropia	2.5%
675	Hypotension, Orthostatic	2.5%
676	Sleep Apnea Syndromes	2.5%
677	Polymyositis	2.5%
678	Post-Exercise Hypotension	2.5%
679	Disorders of Excessive Somnolence	2.5%
680	Sleep Initiation and Maintenance Disorders	2.5%
681	Night Terrors	2.5%
682	Somnambulism	2.5%
683	Trigeminal Nerve Disorder	2.5%
684	Transient Insomnia	2.5%
685	Sleep Paralysis	2.5%
686	Chronic Insomnia	2.5%
687	REM Sleep Behavior Disorder	2.5%
688	Hypersomnia	2.5%
689	Dermal Sinus	2.5%
690	Dysgeusia	2.5%
691	Formication	2.5%
692	Hyperalgesia	2.5%
693	Hyperesthesia	2.5%
694	Hypesthesia	2.5%
695	Language Disorders	2.5%
696	Numbness	2.5%
697	Paresthesia	2.5%
698	Paraparesis, Spastic	2.5%
699	Spina Bifida Cystica	2.5%
700	Trismus	2.5%
701	Spina Bifida Occulta	2.5%
702	Epilepsia Partialis Continua	2.5%
703	Hypogeusia	2.5%
704	Meningeal Carcinomatosis	2.5%
705	Brown-Sequard Syndrome	2.5%
706	Lissencephaly	2.5%
707	Polymicrogyria	2.5%
708	Pachygyria	2.5%
709	Schizencephaly	2.5%
710	Lockjaw	2.5%
711	Allodynia	2.5%
712	Lead Poisoning, Nervous System, Childhood	2.5%
713	Lead Poisoning, Nervous System, Adult	2.5%
714	Periventricular Nodular Heterotopia	2.5%
715	Ageusia	2.5%
716	Acoustic Neuroma	2.4%
717	Alexia	2.3%
718	Dyslexia	2.3%
719	Duane Retraction Syndrome	2.3%
720	Consciousness Disorders	2.3%
721	Mental Retardation	2.3%
722	Muscle Weakness	2.3%
723	Depressed Level of Consciousness	2.3%
724	Mental deficiency	2.3%
725	Intellectual Disability	2.3%
726	Mobius Syndrome	2.3%
727	Bell Palsy	2.3%
728	Catatonia	2.3%
729	Herpes Zoster Oticus	2.3%
730	Aphonia	2.2%
731	Sleep Deprivation	2.2%
732	Dysphonia	2.2%
733	Neurofibrosarcoma	2.2%
734	Eye Injuries	2.1%
735	Sleep Apnea, Obstructive	2.1%
736	Sleep Apnea, Central	2.1%
737	Narcolepsy	2.1%
738	Trigeminal Neuralgia	2.1%
739	Kleine-Levin Syndrome	2.1%
740	Agraphia	2.1%
741	Anomia	2.1%
742	Cluttering	2.1%
743	Language Development Disorders	2.1%
744	Speech Disorders	2.1%
745	Syncope	2.1%
746	Stupor	2.1%
747	Dysgraphia	2.1%
748	Presyncope	2.1%
749	Dyslalia	2.1%
750	Muscular Dystrophy	2%
751	Congenital nystagmus	2%
752	Orbital Myositis	2%
753	Diplopia	2%
754	Muscle Rigidity	2%
755	Muscle Spasticity	2%
756	Scotoma	2%
757	Photophobia	2%
758	Cogwheel Rigidity	2%
759	Hemifacial Spasm	2%
760	Amaurosis	2%
761	Blindness	2%
762	Nuchal Rigidity	2%
763	Pyomyositis	2%
764	Agnosia	2%
765	Apraxias	2%
766	Hallucinations	2%
767	Hemianopsia	2%
768	Hyperacusis	2%
769	Tinnitus	2%
770	Visual Agnosia	2%
771	Anosognosia	2%
772	Wernicke-Korsakoff Syndrome	2%
773	Phonophobia	2%
774	Hearing Loss	2%
775	Sarcopenia	2%
776	Wernicke Encephalopathy	2%
777	Myalgia	1.9%
778	Cataplexy	1.9%
779	Aphasia	1.8%
780	Articulation Disorders	1.8%
781	Echolalia	1.8%
782	Stuttering	1.8%
783	Dysphasia	1.8%
784	Dysarthria	1.7%
785	Aicardi's syndrome	1.7%
786	Hoarseness	1.7%
787	Amnesia	1.7%
788	Delirium	1.7%
789	Dissociative Amnesia	1.7%
790	Color blindness	1.7%
791	Global Amnesia	1.7%
792	Eye Burns	1.7%
793	Cri-du-Chat Syndrome	1.7%
794	Down Syndrome	1.7%
795	Trisomy 21	1.7%
796	POEMS Syndrome	1.7%
797	Alcohol Withdrawal Delirium	1.7%
798	Meningioma	1.7%
799	Williams Syndrome	1.7%
800	Welander Distal Myopathy	1.7%
801	Microcephaly	1.7%
802	Amaurosis Fugax	1.7%
803	Blindness, Cortical	1.7%
804	Macrocephaly	1.7%
805	Dyscalculia	1.7%
806	Rett Syndrome	1.7%
807	Deafness	1.6%
808	Hearing Loss, Sudden	1.6%
809	Gerstmann Syndrome	1.6%
810	Hearing Loss, Bilateral	1.6%
811	Hearing Loss, High-Frequency	1.6%
812	Hearing Loss, Mixed Conductive-Sensorineural	1.6%
813	Prosopagnosia	1.6%
814	Apraxia, Ideomotor	1.6%
815	Charles Bonnet Syndrome	1.6%
816	Hearing Loss, Unilateral	1.6%
817	Complete Hearing Loss	1.6%
818	Alien Hand Syndrome	1.6%
819	Deaf Mutism	1.6%
820	Porencephaly	1.6%
821	Mutism	1.5%
822	Selective Mutism	1.5%
823	Holoprosencephaly	1.5%
824	Dermatomyositis	1.4%
825	Corneal Scar	1.4%
826	Phantom pain	1.4%
827	Phantom Limb Pain	1.4%
828	Alexia, Pure	1.4%
829	Muscular Dystrophy, Duchenne	1.4%
830	Retrograde amnesia	1.4%
831	Amnesia, Anterograde	1.4%
832	Corneal Perforation	1.2%
833	Fragile X Syndrome	1.2%
834	Rubinstein-Taybi Syndrome	1.1%

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