MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Cardiovascular Abnormalities

(UMLS:C0243050)

Definition:: Congenital, inherited, or acquired anomalies of the CARDIOVASCULAR SYSTEM, including the HEART and BLOOD VESSELS.
UMLS ID:: C0243050
MeSH ID:: D018376

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.240

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.240

Synonym(s)

Cardiovascular Abnormalities

Abnormality of the cardiovascular system

Cardiac anomaly

Cardiovascular abnormality

Cardiovascular system--Abnormalities

abnormalities cardiovascular

anomaly; cardiovascular system

cardiovascular abnormalities

cardiovascular system; anomaly

10.

cardiovascular system; deformity

11.

deformity; cardiovascular system

Associated Drug(s)

	Name	Reference(s)	Data Source
1	3,4,5,3',4'-pentachlorobiphenyl	25711857	CTD
2	Acetylcysteine	11742581	CTD
3	Aconitine	30639578	CTD
4	Arsenicals	17520054	CTD
5	Ascorbic Acid	20068362	CTD
6	Azacitidine	26712470	CTD
7	Cadmium Chloride	25502771	CTD
8	Dexamethasone	20068362	CTD
9	Dextroamphetamine	3563934	CTD
10	Dichloroacetic Acid	27518881	CTD
11	Diethylstilbestrol	20002218	CTD
12	Etomidate	2742101	CTD
13	Folic Acid	11096168	CTD
14	Indomethacin	7719872	CTD
15	Isotretinoin	2278026 12149069	CTD
16	Lithium	1119612 3053673	CTD
17	Mibefradil	9100294	CTD
18	N-(phosphonomethyl)glycine trimethylsulfonium salt	10627661	CTD
19	Nifedipine	9100294	CTD
20	Ondansetron	30149139	CTD
21	Polychlorinated Dibenzodioxins	22403156	CTD
22	Propylthiouracil	16498810	CTD
23	Trichloroacetic Acid	27518881	CTD
24	Trimethadione	50427	CTD
25	Valproic Acid	11223853 15794725 20025093	CTD
26	Verapamil	9100294	CTD
27	Vitamin E	20068362	CTD
28	Zidovudine	10969349	CTD
29	aluminum phosphide	11742581	CTD
30	ametryne	29427468	CTD
31	aristolochic acid I	22472514	CTD
32	benz(a)anthracene	17112560	CTD
33	bromoform	27518881	CTD
34	dibenzothiophene	15081266	CTD
35	ethyl tert-butyl ether	22609741	CTD
36	flusilazole	22382673 26712470	CTD
37	kenpaullone	25711857	CTD
38	mesaconitine	30639578	CTD
39	netobimin	10453914	CTD
40	phenanthrene	15081266	CTD
41	tertiary-amyl methyl ether	22609741	CTD
42	tetrahydrocurcumin	25502771	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Abnormalities, Drug-Induced	30%
2	Situs Inversus	30%
3	Beckwith-Wiedemann Syndrome	29.6%
4	Wolf-Hirschhorn Syndrome	29.6%
5	Holoprosencephaly	27.3%
6	Smith-Magenis syndrome	24.7%
7	Cri-du-Chat Syndrome	24.3%
8	Down Syndrome	24.3%
9	Trisomy 21	24.3%
10	Anencephaly	23.1%
11	Eye Abnormalities	23.1%
12	Aicardi's syndrome	22.3%
13	Skin Abnormalities	22.2%
14	Myocardial Ischemia	22.2%
15	Lymphatic Abnormalities	22.2%
16	Congenital Microtia	22.2%
17	Prune Belly Syndrome	22%
18	Twins, Conjoined	22%
19	Waardenburg Syndrome	22%
20	Congenital diaphragmatic hernia	21.6%
21	Rubinstein-Taybi Syndrome	21.5%
22	Heart Diseases	21.1%
23	Vascular Diseases	21.1%
24	Ectodermal Dysplasia	20.8%
25	Aplasia Cutis Congenita	20.8%
26	Prader-Willi Syndrome	20.6%
27	Myocardial Reperfusion Injury	19.7%
28	Coronary Aneurysm	19.4%
29	Maxillofacial Abnormalities	19.3%
30	Williams Syndrome	18.6%
31	Coronary Thrombosis	18.6%
32	Coronary Artery Disease	18.6%
33	CHARGE Syndrome	18.6%
34	Thrombophlebitis	18.2%
35	Urogenital Abnormalities	18.2%
36	Aortic Aneurysm	17.9%
37	Aortic Valve Stenosis	17.9%
38	Aortitis	17.9%
39	Cardiomyopathy, Dilated	17.9%
40	Coronary heart disease	17.9%
41	Leriche Syndrome	17.9%
42	Myocardial Infarction	17.9%
43	Periphlebitis	17.9%
44	Phlebitis	17.9%
45	Pulmonary Valve Stenosis	17.9%
46	Thromboangiitis Obliterans	17.9%
47	Acute Coronary Syndrome	17.9%
48	Postphlebitic Syndrome	16.8%
49	Kartagener Syndrome	16.7%
50	Anophthalmos	16.4%
51	Anus, Imperforate	16.4%
52	Hydranencephaly	16.4%
53	Microphthalmos	16.4%
54	Neural Tube Defects	16.4%
55	Tethered Cord Syndrome	16.4%
56	Iniencephaly	16.4%
57	Craniorachischisis	16.4%
58	Limb Deformities, Congenital	16.4%
59	Exencephaly	16.4%
60	Septo-Optic Dysplasia	16.4%
61	Craniofacial Abnormalities	16.4%
62	Cortical Dysplasia	16.4%
63	Malformations of Cortical Development	16.4%
64	Anorectal Malformations	16.4%
65	Hypertrophic Cardiomyopathy	16.3%
66	Hypertrophic obstructive cardiomyopathy	16.3%
67	Microcephaly	16.2%
68	Macrocephaly	16.2%
69	Dextrocardia	16.2%
70	Bloom Syndrome	16.1%
71	Blue Toe Syndrome	16%
72	Supravalvular aortic stenosis	15.8%
73	Lown-Ganong-Levine Syndrome	15.8%
74	Coronary Occlusion	15.8%
75	Aortic Aneurysm, Abdominal	15.8%
76	Aortic Aneurysm, Thoracic	15.8%
77	Microvascular Angina	15.8%
78	Coronary Stenosis	15.8%
79	Genetic Diseases, Inborn	15.8%
80	ST segment elevation myocardial infarction	15.8%
81	Aortic Rupture	15.6%
82	Nail-Patella Syndrome	15.5%
83	Pregnancy Complications, Cardiovascular	15.4%
84	Xeroderma	15.3%
85	Mobius Syndrome	15.3%
86	Porencephaly	15.3%
87	Aneurysm	15%
88	Angiomatosis	15%
89	Aortic Diseases	15%
90	Arterial Occlusive Diseases	15%
91	Cardiac Tamponade	15%
92	Endocarditis	15%
93	Cardiac Arrest	15%
94	Heart failure	15%
95	Hyperemia	15%
96	Hypotension	15%
97	Pericardial effusion	15%
98	Pericarditis	15%
99	Pneumopericardium	15%
100	Cor pulmonale	15%
101	Superior Vena Cava Syndrome	15%
102	Telangiectasis	15%
103	Vasculitis	15%
104	Venous Insufficiency	15%
105	Ventricular Outflow Obstruction	15%
106	Peripheral Vascular Diseases	15%
107	Embolism and Thrombosis	15%
108	Angiodysplasia	15%
109	Ventricular Dysfunction	15%
110	Capillary Leak Syndrome	15%
111	Cardiomyopathies	15%
112	Pleuropericarditis	15%
113	Prehypertension	15%
114	Carotid Artery Thrombosis	15%
115	Classical Lissencephalies and Subcortical Band Heterotopias	15%
116	Embolism, Amniotic Fluid	14.9%
117	Coronary Restenosis	14.8%
118	Acrocephalosyndactylia	14.8%
119	Retinal Vein Occlusion	14.7%
120	Craniosynostosis	14.6%
121	Syndactyly	14.6%
122	Brachycephaly	14.6%
123	Fragile X Syndrome	14.5%
124	Kounis Syndrome	14.3%
125	Heart Block	14.1%
126	Tachycardia	14.1%
127	Tachyarrhythmia	14.1%
128	Malignant Atrophic Papulosis	14.1%
129	Alstrom Syndrome	14%
130	Shwartzman Phenomenon	14%
131	Angina Pectoris	13.9%
132	Marfan Syndrome	13.9%
133	Polycystic Kidney Diseases	13.8%
134	Amelia	13.3%
135	Arachnodactyly	13.3%
136	Ectromelia	13.3%
137	Hemimelia	13.3%
138	Meningomyelocele	13.3%
139	Phocomelia	13.3%
140	Sirenomelia	13.3%
141	Spina Bifida	13.3%
142	Polydactyly	13.3%
143	Brachydactyly	13.3%
144	Plagiocephaly	13.3%
145	Lower Extremity Deformities, Congenital	13.3%
146	Upper Extremity Deformities, Congenital	13.3%
147	Moyamoya Disease	13.2%
148	Scimitar Syndrome	13.2%
149	Intracranial Embolism and Thrombosis	13.2%
150	Carotid Stenosis	13.1%
151	Intracranial Aneurysm	13.1%
152	Bacterial Endocarditis	13.1%
153	Blepharophimosis	13%
154	Laryngostenosis	13%
155	Mouth Abnormalities	13%
156	Sick Sinus Syndrome	13%
157	Primary Ciliary Dyskinesia	13%
158	Pseudoxanthoma Elasticum	13%
159	Poland Syndrome	12.9%
160	Cockayne Syndrome	12.9%
161	Esophageal Atresia	12.9%
162	Intestinal Atresia	12.9%
163	Horseshoe Kidney	12.9%
164	Pectus excavatum	12.9%
165	Klippel-Feil Syndrome	12.8%
166	Gastroschisis	12.8%
167	Synostosis	12.8%
168	Acrodermatitis	12.7%
169	Lymphangiectasis, Intestinal	12.7%
170	Gianotti-Crosti Syndrome	12.7%
171	Cleft Palate	12.5%
172	Polyarteritis Nodosa	12.5%
173	Shock, Cardiogenic	12.5%
174	Takayasu Arteritis	12.5%
175	Adams-Stokes Syndrome	12.4%
176	Atrioventricular Block	12.4%
177	Bundle-Branch Block	12.4%
178	Atrial Premature Complexes	12.4%
179	Sinoatrial Block	12.4%
180	Tachycardia, Paroxysmal	12.4%
181	Supraventricular tachycardia	12.4%
182	Tachycardia, Ventricular	12.4%
183	Wolff-Parkinson-White Syndrome	12.4%
184	Tachycardia, Reciprocating	12.4%
185	Intracranial Arteriosclerosis	12.4%
186	Cerebral Atherosclerosis	12.4%
187	Cerebral Arteriosclerosis	12.4%
188	Angina, Unstable	12.3%
189	Jaw Abnormalities	12.3%
190	Retinal Dysplasia	12.2%
191	Aneurysm, Dissecting	12.2%
192	Aortic Valve Insufficiency	12.2%
193	Arteriosclerosis	12.2%
194	Arteritis	12.2%
195	Restrictive cardiomyopathy	12.2%
196	Embolism	12.2%
197	Endocardial Fibroelastosis	12.2%
198	Erythromelalgia	12.2%
199	Fibromuscular Dysplasia	12.2%
200	Heart Rupture, Post-Infarction	12.2%
201	Malignant Hypertension	12.2%
202	Mitral Valve Insufficiency	12.2%
203	Mitral Valve Stenosis	12.2%
204	Myocarditis	12.2%
205	Pericarditis, Constrictive	12.2%
206	Pulmonary Valve Insufficiency	12.2%
207	Raynaud Disease	12.2%
208	Thromboembolism	12.2%
209	Thrombosis	12.2%
210	Tricuspid Valve Insufficiency	12.2%
211	Tricuspid Valve Stenosis	12.2%
212	Essential Hypertension	12.2%
213	Aneurysm, Ruptured	12.2%
214	Iliac Aneurysm	12.2%
215	Pulmonary artery stenosis	12.2%
216	Ventricular Dysfunction, Left	12.2%
217	Right Ventricular Dysfunction	12.2%
218	White Coat Hypertension	12.2%
219	Systemic Vasculitis	12.2%
220	Endomyocardial Fibrosis	12.2%
221	Carditis	12.2%
222	Heart Failure, Systolic	12.2%
223	Heart Failure, Diastolic	12.2%
224	Embolus	12.2%
225	Aniridia	12.1%
226	Turner Syndrome	12.1%
227	Cerebral Thrombosis	12%
228	Intracranial Embolism	12%
229	Intracranial Thrombosis	12%
230	Epidermolysis Bullosa	11.9%
231	Abnormalities, Radiation-Induced	11.9%
232	Smith-Lemli-Opitz Syndrome	11.8%
233	Dermal Sinus	11.8%
234	Spina Bifida Cystica	11.8%
235	Spina Bifida Occulta	11.8%
236	Lissencephaly	11.8%
237	Polymicrogyria	11.8%
238	Pachygyria	11.8%
239	Schizencephaly	11.8%
240	Periventricular Nodular Heterotopia	11.8%
241	Klinefelter Syndrome	11.7%
242	Ichthyosis, X-Linked	11.6%
243	Tachycardia, Atrioventricular Nodal Reentry	11.6%
244	Tachycardia, Ectopic Atrial	11.6%
245	Tachycardia, Ectopic Junctional	11.6%
246	Sinus Tachycardia	11.6%
247	Torsades de Pointes	11.6%
248	Accelerated Idioventricular Rhythm	11.6%
249	Angina Pectoris, Variant	11.6%
250	Long QT Syndrome	11.6%
251	Tricuspid Atresia	11.6%
252	Arrhythmogenic Right Ventricular Dysplasia	11.6%
253	Fetal Diseases	11.5%
254	Vascular System Injuries	11.5%
255	Sinus Thrombosis, Intracranial	11.4%
256	Polycystic Kidney, Autosomal Dominant	11.3%
257	Compartment syndromes	11.1%
258	Hepatic Veno-Occlusive Disease	11.1%
259	Peliosis Hepatis	11.1%
260	Varicocele	11.1%
261	Cardiac Output, High	11.1%
262	Myocardial Stunning	11.1%
263	Low Cardiac Output Syndrome	11.1%
264	Cavernous Sinus Thrombosis	11.1%
265	Sagittal Sinus Thrombosis	11.1%
266	Micrognathism	11%
267	Pierre Robin Syndrome	11%
268	Cerebrovascular Disorders	10.9%
269	Diabetic Angiopathies	10.9%
270	Cardiomegaly	10.9%
271	Postpericardiotomy Syndrome	10.9%
272	Reperfusion Injury	10.9%
273	Splenic Infarction	10.9%
274	Cerebrovascular Insufficiency	10.9%
275	Vascular Neoplasms	10.9%
276	Spinal Cord Vascular Diseases	10.9%
277	Cardiac Hypertrophy	10.9%
278	Vasoplegia	10.9%
279	Aortic Valve Prolapse	10.8%
280	Arteriosclerosis Obliterans	10.8%
281	Arthrogryposis	10.8%
282	Atherosclerosis	10.8%
283	Choanal Atresia	10.8%
284	Air Embolism	10.8%
285	Endarteritis	10.8%
286	Tracheobronchomegaly	10.8%
287	Tricuspid Valve Prolapse	10.8%
288	Venous Thrombosis	10.8%
289	Deep Vein Thrombosis	10.8%
290	Takotsubo Cardiomyopathy	10.8%
291	Venous Thromboembolism	10.8%
292	Laryngocele	10.8%
293	Hemorrhoids	10.8%
294	Thoracic Outlet Syndrome	10.8%
295	Lemierre Syndrome	10.8%
296	Noonan Syndrome	10.8%
297	Rheumatic Heart Disease	10.8%
298	Choledochal Cyst	10.7%
299	Hermaphroditism	10.7%
300	Disorders of Sex Development	10.7%
301	Cryptorchidism	10.6%
302	Hypospadias	10.6%
303	Central Nervous System Cysts	10.5%
304	Dural Arteriovenous Fistula	10.5%
305	Dental Enamel Hypoplasia	10.5%
306	Hypodontia	10.5%
307	Macrostomia	10.5%
308	Meningocele	10.5%
309	Microstomia	10.5%
310	Encephalocele	10.5%
311	Dandy-Walker Syndrome	10.5%
312	Craniofacial Dysostosis	10.4%
313	Angioedemas, Hereditary	10.4%
314	POEMS Syndrome	10.3%
315	Infarction, Middle Cerebral Artery	10.3%
316	Infarction, Anterior Cerebral Artery	10.3%
317	Infarction, Posterior Cerebral Artery	10.3%
318	Romano-Ward Syndrome	10.2%
319	Brain Infarction	10.2%
320	Giant Cell Arteritis	10.1%
321	Temporal Arteritis	10.1%
322	Abdominal Cramps	10%
323	Amniotic Band Syndrome	10%
324	Asphyxia Neonatorum	10%
325	Infant, Premature, Diseases	10%
326	Infantile Colic	10%
327	Vasculitis, Central Nervous System	10%
328	Hyperkeratosis, Epidermolytic	9.8%
329	Retrognathia	9.8%
330	Cystic Fibrosis	9.8%
331	Charcot-Marie-Tooth Disease	9.7%
332	Antley-Bixler Syndrome Phenotype	9.7%
333	Subarachnoid Hemorrhage, Traumatic	9.6%
334	Carotid Artery, Internal, Dissection	9.6%
335	Sjogren-Larsson Syndrome	9.6%
336	Cerebral Infarction	9.5%
337	Brain Stem Infarctions	9.5%
338	Subacute Bacterial Endocarditis	9.3%
339	Lateral Medullary Syndrome	9.2%
340	Leukomalacia, Periventricular	9.2%
341	Laryngomalacia	9.2%
342	Kallmann Syndrome	9.1%
343	Retinal Artery Occlusion	9.1%
344	Retinal Vasculitis	9.1%
345	Hypertensive Retinopathy	9.1%
346	Pectus carinatum	9.1%
347	Bladder Exstrophy	9%
348	Epispadias	9%
349	Hand-Arm Vibration Syndrome	9%
350	Hyperandrogenism	8.9%
351	Anterior Compartment Syndrome	8.9%
352	Sinus Arrhythmia	8.9%
353	Atrial Fibrillation	8.9%
354	Atrial Flutter	8.9%
355	Edema, Cardiac	8.9%
356	Ventricular Fibrillation	8.9%
357	Vasculitis, Leukocytoclastic, Cutaneous	8.9%
358	Ventricular Flutter	8.9%
359	Parasystole	8.9%
360	Paroxysmal atrial fibrillation	8.9%
361	Gastric Antral Vascular Ectasia	8.9%
362	Bradycardia	8.9%
363	Diabetic Cardiomyopathies	8.9%
364	Abdominal Compartment Syndrome	8.9%
365	Multicystic Dysplastic Kidney	8.9%
366	Cardiomyopathy, Alcoholic	8.8%
367	Carotid Artery Diseases	8.8%
368	Brain Ischemia	8.8%
369	Hypotension, Orthostatic	8.8%
370	Cerebrovascular accident	8.8%
371	Varicose Ulcer	8.8%
372	Sudden Cardiac Death	8.8%
373	Left Ventricular Hypertrophy	8.8%
374	Right Ventricular Hypertrophy	8.8%
375	Vasospasm, Intracranial	8.8%
376	Spinal Cord Ischemia	8.8%
377	Intracranial Arterial Diseases	8.8%
378	Primary Graft Dysfunction	8.8%
379	Post-Exercise Hypotension	8.8%
380	Prognathism	8.8%
381	Chagas Cardiomyopathy	8.8%
382	Vertebral Artery Dissection	8.8%
383	Optic Neuropathy, Ischemic	8.7%
384	Anterior Ischemic Optic Neuropathy	8.7%
385	Mesenteric vascular insufficiency	8.7%
386	Goldenhar Syndrome	8.7%
387	Platybasia	8.7%
388	Gonadal Dysgenesis	8.6%
389	Bronchomalacia	8.6%
390	Adrenogenital Syndrome	8.6%
391	Tracheomalacia	8.6%
392	Ovotesticular Disorders of Sex Development	8.6%
393	Arteriovenous fistula	8.5%
394	Angioedema	8.5%
395	Colitis, Ischemic	8.4%
396	Xeroderma Pigmentosum	8.3%
397	Meconium Aspiration Syndrome	8.2%
398	Intermittent Claudication	8.1%
399	Pulmonary Embolism	8.1%
400	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	8.1%
401	Tuberous Sclerosis	8.1%
402	CREST Syndrome	8%
403	No-Reflow Phenomenon	8%
404	Sinus Arrest, Cardiac	7.9%
405	Cerebral Arterial Diseases	7.9%
406	Vertebrobasilar Insufficiency	7.9%
407	Anterior Spinal Artery Syndrome	7.9%
408	Basilar Artery Stenosis	7.9%
409	Vertebral Artery Stenosis	7.9%
410	Intracranial Hemorrhage, Hypertensive	7.9%
411	Transient Cerebral Ischemia	7.9%
412	Zellweger Syndrome	7.8%
413	Neoplastic Syndromes, Hereditary	7.7%
414	Mandibulofacial Dysostosis	7.7%
415	Refsum Disease	7.6%
416	Hepatic Vein Thrombosis	7.6%
417	Budd-Chiari Syndrome	7.6%
418	Carotid Artery Injuries	7.6%
419	Pulmonary Infarction	7.5%
420	Subclavian Steal Syndrome	7.4%
421	Basal Cell Nevus Syndrome	7.4%
422	Familial Mediterranean Fever	7.3%
423	Talipes	7.3%
424	Anemia, Neonatal	7.3%
425	Multiple Epiphyseal Dysplasia	7.3%
426	Osteochondrodysplasias	7.3%
427	Pelger-Huet Anomaly	7.3%
428	Persistent Fetal Circulation Syndrome	7.3%
429	Werner Syndrome	7.3%
430	Myasthenic Syndromes, Congenital	7.3%
431	Basal Ganglia Hemorrhage	7.3%
432	Umbilical hernia	7.2%
433	Mesenteric Vascular Occlusion	7.1%
434	Mucocutaneous Lymph Node Syndrome	7.1%
435	Diabetic Retinopathy	7.1%
436	Sturge-Weber Syndrome	7.1%
437	Livedo Reticularis	7%
438	Aortic coarctation	7%
439	Cor Triatriatum	7%
440	Coronary Vessel Anomalies	7%
441	Patent ductus arteriosus	7%
442	Dyspnea, Paroxysmal	7%
443	Ebstein Anomaly	7%
444	Heart Septal Defects	7%
445	Renal hypertension	7%
446	Renal Artery Obstruction	7%
447	Renal Artery Stenosis	7%
448	Tetralogy of Fallot	7%
449	Transposition of Great Vessels	7%
450	Hypoplastic Left Heart Syndrome	7%
451	May-Thurner Syndrome	7%
452	Congenital clubfoot	7%
453	Vertical Talus	7%
454	Hemangioma, Cavernous	6.9%
455	Basal Ganglia Cerebrovascular Disease	6.9%
456	Ataxia Telangiectasia	6.9%
457	Vascular Headaches	6.9%
458	Anemia, Sickle Cell	6.9%
459	Thalassemia	6.9%
460	Putaminal Hemorrhage	6.9%
461	Scurvy	6.9%
462	Behcet Syndrome	6.9%
463	Muscular Dystrophy, Duchenne	6.9%
464	Rett Syndrome	6.9%
465	Carcinoid Heart Disease	6.8%
466	Albinism	6.5%
467	Fabry Disease	6.5%
468	Dementia, Vascular	6.3%
469	Mucopolysaccharidosis II	6.3%
470	Aortopulmonary Septal Defect	6.2%
471	Double Outlet Right Ventricle	6.2%
472	Endocardial Cushion Defects	6.2%
473	Hypertension, Renovascular	6.2%
474	Subarachnoid Hemorrhage	6.2%
475	Hypoxia-Ischemia, Brain	6.2%
476	Myocardial bridging	6.2%
477	Cerebral Hemorrhage	6.2%
478	Aorticopulmonary Septal Defect	6.2%
479	Hereditary Angioedema Type III	6.1%
480	Hereditary Angioedema Types I and II	6.1%
481	Dwarfism	6%
482	Granulomatosis with polyangiitis	5.9%
483	Neonatal Abstinence Syndrome	5.9%
484	Ischemic contracture	5.8%
485	Cerebral Amyloid Angiopathy	5.8%
486	Truncus Arteriosus, Persistent	5.8%
487	Cryoglobulinemia	5.7%
488	Fetal Growth Retardation	5.7%
489	Diabetic Foot	5.7%
490	Muscular Dystrophy	5.7%
491	Osteogenesis Imperfecta	5.7%
492	Fetal Hypoxia	5.7%
493	Congenital nystagmus	5.7%
494	Fetal Alcohol Spectrum Disorders	5.7%
495	Sickle Cell Trait	5.7%
496	Toxoplasmosis, Congenital	5.6%
497	Syphilis, Congenital	5.6%
498	Menkes Kinky Hair Syndrome	5.5%
499	Paralysis, Obstetric	5.5%
500	Retinopathy of Prematurity	5.5%
501	Amino Acid Metabolism, Inborn Errors	5.4%
502	Carbohydrate Metabolism, Inborn Errors	5.4%
503	Metal Metabolism, Inborn Errors	5.4%
504	Progeria	5.4%
505	Lysosomal Storage Diseases	5.4%
506	Cytochrome-c Oxidase Deficiency	5.4%
507	Peroxisomal Disorders	5.4%
508	Bronchopulmonary Dysplasia	5.3%
509	Pituitary Apoplexy	5.2%
510	Wiskott-Aldrich Syndrome	5.1%
511	Neuronal Ceroid-Lipofuscinoses	5.1%
512	Shy-Drager Syndrome	4.9%
513	Purpura, Hyperglobulinemic	4.9%
514	Autoimmune Lymphoproliferative Syndrome	4.8%
515	Congenital Hyperinsulinism	4.7%
516	Chorioamnionitis	4.7%
517	Lupus Vasculitis, Central Nervous System	4.6%
518	Myotonic Dystrophy	4.5%
519	Adrenoleukodystrophy	4.5%
520	Glycogen storage disease type II	4.4%
521	Rheumatoid Vasculitis	4.4%
522	Alkaptonuria	4.4%
523	Glycogen Storage Disease	4.4%
524	Hypophosphatasia	4.4%
525	Propionic acidemia	4.4%
526	Dihydropyrimidine Dehydrogenase Deficiency	4.4%
527	Cystinosis	4.4%
528	Respiratory Distress Syndrome, Newborn	4.3%
529	Denys-Drash Syndrome	4.3%
530	Mucopolysaccharidosis III	4.3%
531	Acute Chest Syndrome	4.3%
532	Cutis Laxa	4.3%
533	Waldenstrom Macroglobulinemia	4.3%
534	Multiple Myeloma	4.3%
535	Retinitis Pigmentosa	4.3%
536	Pigmentary retinopathy	4.3%
537	Porokeratosis	4.2%
538	Keratoderma, Palmoplantar	4.2%
539	MELAS Syndrome	4.2%
540	Chronic granulomatous disease	4.2%
541	Galactosemias	4.2%
542	Urea Cycle Disorders, Inborn	4.2%
543	Tyrosinemias	4.2%
544	Welander Distal Myopathy	4.2%
545	Hepatolenticular Degeneration	4.1%
546	Amyloid Neuropathies, Familial	4.1%
547	Hydrops Fetalis	4%
548	Glycogen Storage Disease Type I	3.9%
549	Glycogen Storage Disease Type V	3.9%
550	Gaucher Disease	3.8%
551	Optic Atrophy, Hereditary, Leber	3.7%
552	Hyperphosphaturia	3.7%
553	Tay-Sachs Disease	3.6%
554	Duane Retraction Syndrome	3.6%
555	Hematoma, Subdural	3.6%
556	Hematoma, Epidural, Cranial	3.6%
557	Homocystinuria	3.6%
558	Porphyrias, Hepatic	3.5%
559	Leigh Disease	3.5%
560	Canavan Disease	3.5%
561	Alexander Disease	3.5%
562	Hyaline Membrane Disease	3.5%
563	Peutz-Jeghers Syndrome	3.5%
564	Myotonia Congenita	3.5%
565	Thrombasthenia	3.5%
566	Antithrombin III Deficiency	3.5%
567	Protein C Deficiency	3.5%
568	Brain Diseases, Metabolic, Inborn	3.5%
569	Afibrinogenemia	3.4%
570	Dystonia Musculorum Deformans	3.4%
571	Factor VII Deficiency	3.4%
572	Factor X Deficiency	3.4%
573	Factor XII Deficiency	3.4%
574	Hemophilia A	3.4%
575	Hypolipoproteinemias	3.4%
576	Papillon-Lefevre Disease	3.4%
577	Activated Protein C Resistance	3.4%
578	Factor II deficiency	3.4%
579	Factor VIII Deficiency	3.4%
580	Factor V deficiency	3.4%
581	Factor XI Deficiency	3.4%
582	Hypoprothrombinemias	3.4%
583	Hyperlipidemia, Familial Combined	3.4%
584	Hyperlipoproteinemia Type III	3.4%
585	Fanconi Anemia	3.4%
586	Nesidioblastosis	3.4%
587	Hematoma, Subdural, Intracranial	3.4%
588	Hematoma, Subdural, Chronic	3.4%
589	Hematoma, Subdural, Acute	3.4%
590	Lafora Disease	3.4%
591	Unverricht-Lundborg Syndrome	3.4%
592	Anemia, Diamond-Blackfan	3.4%
593	Ophthalmia Neonatorum	3.4%
594	Niemann-Pick Disease, Type C	3.3%
595	Carbamoyl-Phosphate Synthase I Deficiency Disease	3.3%
596	Brain Hemorrhage, Traumatic	3.1%
597	Hypoalphalipoproteinemias	3.1%
598	Multiple Endocrine Neoplasia	3.1%
599	Congenital Hypothyroidism	3%
600	Dermatitis, Atopic	3%
601	Familial Periodic Paralysis	2.9%
602	Lactose Intolerance	2.9%
603	Variegate Porphyria	2.9%
604	Acute intermittent porphyria	2.9%
605	Porphyria Cutanea Tarda	2.9%
606	Hyperhomocysteinemia	2.8%
607	Renal Aminoacidurias	2.8%
608	Fanconi Syndrome	2.8%
609	Pseudohypoaldosteronism	2.8%
610	Liddle Syndrome	2.8%
611	Hyperlipoproteinemia Type IV	2.8%
612	Hyperlipoproteinemia Type V	2.8%
613	Kearns-Sayre syndrome	2.8%
614	Kernicterus	2.6%
615	Hypokalemic periodic paralysis	2.6%
616	Cystinuria	2.5%
617	Gout	2.5%
618	Multiple Endocrine Neoplasia Type 1	2.5%
619	Pseudohypoparathyroidism	2.5%
620	Friedreich Ataxia	2.4%
621	Renal tubular acidosis	2.4%
622	Huntington Disease	2.3%
623	Arthritis, Gouty	2.2%
624	Familial Hypophosphatemic Rickets	2.1%
625	Nephroblastoma	2%
626	Glycosuria, Renal	1.9%
627	Adenomatous Polyposis Coli	1.8%

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