MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Dextrocardia

(UMLS:C0011813)

Definition:: A congenital defect in which the heart is located on the right side of the THORAX instead of on the left side (levocardia, the normal position). When dextrocardia is accompanied with inverted HEART ATRIA, a right-sided STOMACH, and a left-sided LIVER, the combination is called dextrocardia with SITUS INVERSUS. Dextrocardia may adversely affect other thoracic organs.
UMLS ID:: C0011813
MeSH ID:: D003914

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.240.400.280|C14.280.400.280

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.131.240.400.280|C16.131.810.250

Synonym(s)

Dextrocardia

DEXTROCARDIA

Heart in right chest

Heart predominantly in right hemithorax

Heart tip and four chambers point towards right side of body

Right sided heart

Thoracic situs inversus

dextrocardia

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Paroxetine	FAERS: 16		US FAERS
2	Venlafaxine Hydrochloride	FAERS: 15		US FAERS
3	Fluoxetine	FAERS: 9		US FAERS
4	Ondansetron	FAERS: 6		US FAERS
5	Sertraline	FAERS: 6		US FAERS
6	Buprenorphine	FAERS: 3		US FAERS
7	17 alpha-Hydroxyprogesterone Caproate	FAERS: 2		US FAERS
8	Citalopram	FAERS: 2		US FAERS
9	Imatinib Mesylate	FAERS: 2		US FAERS
10	Isotretinoin	FAERS: 2		US FAERS
11	Paroxetine	FAERS: 2		US FAERS
12	Valproic Acid	FAERS: 2		US FAERS
13	Valproic Acid	FAERS: 2		US FAERS
14	eletriptan	FAERS: 2		US FAERS
15	Carbon Dioxide	FAERS: 1		US FAERS
16	Citalopram	FAERS: 1		US FAERS
17	Citalopram	FAERS: 1		US FAERS
18	Methotrexate	FAERS: 1		US FAERS
19	NuvaRing	FAERS: 1		US FAERS
20	Tretinoin	FAERS: 1		US FAERS
21	adefovir dipivoxil	FAERS: 1		US FAERS
22	amitriptyline, chlordiazepoxide drug combination	FAERS: 1		US FAERS
23	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride			OFFSIDES
24	Adapalene			OFFSIDES
25	Atorvastatin			OFFSIDES
26	Cefixime			OFFSIDES
27	Dapsone			OFFSIDES
28	Gemfibrozil	Canada Vigilance: 1		Canada Vigilance
29	Lisinopril			OFFSIDES
30	Methotrimeprazine			OFFSIDES
31	Mianserin			OFFSIDES
32	Nitrofurantoin			OFFSIDES
33	Norethindrone		4416533	CTD
34	Saquinavir			OFFSIDES
35	Sumatriptan			OFFSIDES
36	Warfarin		8025399	CTD
37	efavirenz			OFFSIDES
38	lamivudine, zidovudine drug combination			OFFSIDES
39	propiomazine			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Tricuspid Atresia	49.2%
2	Arrhythmogenic Right Ventricular Dysplasia	49.2%
3	Aortic coarctation	48.6%
4	Cor Triatriatum	48.6%
5	Coronary Vessel Anomalies	48.6%
6	Patent ductus arteriosus	48.6%
7	Ebstein Anomaly	48.6%
8	Heart Septal Defects	48.6%
9	Tetralogy of Fallot	48.6%
10	Transposition of Great Vessels	48.6%
11	Hypoplastic Left Heart Syndrome	48.6%
12	Marfan Syndrome	41.2%
13	Noonan Syndrome	39.2%
14	Ectopia Cordis	39%
15	Aortopulmonary Septal Defect	36.4%
16	Double Outlet Right Ventricle	36.4%
17	Endocardial Cushion Defects	36.4%
18	Myocardial bridging	36.4%
19	Aorticopulmonary Septal Defect	36.4%
20	Truncus Arteriosus, Persistent	30.4%
21	Wolff-Parkinson-White Syndrome	29.4%
22	Long QT Syndrome	29.3%
23	Turner Syndrome	27.2%
24	Dural Arteriovenous Fistula	25%
25	Scimitar Syndrome	24.3%
26	Holoprosencephaly	23.7%
27	Beckwith-Wiedemann Syndrome	23.2%
28	Wolf-Hirschhorn Syndrome	23.2%
29	May-Thurner Syndrome	22.2%
30	Abnormalities, Drug-Induced	22.1%
31	Romano-Ward Syndrome	22%
32	Single umbilical artery	21.4%
33	Aicardi's syndrome	20.8%
34	Smith-Magenis syndrome	20.5%
35	Myocardial Ischemia	20.3%
36	Cri-du-Chat Syndrome	20.2%
37	Down Syndrome	20.2%
38	Trisomy 21	20.2%
39	Rubinstein-Taybi Syndrome	19.2%
40	Eye Abnormalities	19.1%
41	Arteriovenous fistula	19%
42	Skin Abnormalities	18.6%
43	Lymphatic Abnormalities	18.6%
44	Congenital Microtia	18.6%
45	Congenital diaphragmatic hernia	18.3%
46	Ectodermal Dysplasia	18.1%
47	Aplasia Cutis Congenita	18.1%
48	Prader-Willi Syndrome	17.9%
49	Aortic Valve Stenosis	17.7%
50	Cardiomyopathy, Dilated	17.7%
51	Pulmonary Valve Stenosis	17.7%
52	Myocardial Reperfusion Injury	17.6%
53	Anencephaly	17%
54	Urogenital Abnormalities	16.4%
55	Cardiovascular Abnormalities	16.2%
56	Cardiac Tamponade	16.1%
57	Endocarditis	16.1%
58	Cardiac Arrest	16.1%
59	Heart failure	16.1%
60	Pericardial effusion	16.1%
61	Pericarditis	16.1%
62	Pneumopericardium	16.1%
63	Cor pulmonale	16.1%
64	Ventricular Outflow Obstruction	16.1%
65	Ventricular Dysfunction	16.1%
66	Cardiomyopathies	16.1%
67	Pleuropericarditis	16.1%
68	Williams Syndrome	15.6%
69	CHARGE Syndrome	15.3%
70	Heart Block	15.2%
71	Tachycardia	15.2%
72	Tachyarrhythmia	15.2%
73	Maxillofacial Abnormalities	15%
74	Kartagener Syndrome	14.3%
75	Hypertrophic Cardiomyopathy	14.2%
76	Hypertrophic obstructive cardiomyopathy	14.2%
77	Prune Belly Syndrome	13.9%
78	Twins, Conjoined	13.9%
79	Waardenburg Syndrome	13.9%
80	Vascular Diseases	13.8%
81	Cardiac Output, High	13.6%
82	Myocardial Stunning	13.6%
83	Low Cardiac Output Syndrome	13.6%
84	Nail-Patella Syndrome	13.5%
85	Cardiomegaly	13.4%
86	Postpericardiotomy Syndrome	13.4%
87	Cardiac Hypertrophy	13.4%
88	Xeroderma	13.4%
89	Mobius Syndrome	13.4%
90	Rheumatic Heart Disease	13.3%
91	Coronary heart disease	13.3%
92	Myocardial Infarction	13.3%
93	Acute Coronary Syndrome	13.3%
94	Supravalvular aortic stenosis	13.1%
95	Lown-Ganong-Levine Syndrome	13.1%
96	Genetic Diseases, Inborn	13.1%
97	Sick Sinus Syndrome	13%
98	Coronary Aneurysm	12.2%
99	Abnormalities, Radiation-Induced	12.2%
100	Alstrom Syndrome	11.8%
101	Bacterial Endocarditis	11.8%
102	Anophthalmos	11.7%
103	Anus, Imperforate	11.7%
104	Hydranencephaly	11.7%
105	Microphthalmos	11.7%
106	Neural Tube Defects	11.7%
107	Tethered Cord Syndrome	11.7%
108	Iniencephaly	11.7%
109	Craniorachischisis	11.7%
110	Limb Deformities, Congenital	11.7%
111	Exencephaly	11.7%
112	Septo-Optic Dysplasia	11.7%
113	Craniofacial Abnormalities	11.7%
114	Cortical Dysplasia	11.7%
115	Malformations of Cortical Development	11.7%
116	Anorectal Malformations	11.7%
117	Bloom Syndrome	11.6%
118	Cockayne Syndrome	11.6%
119	Pregnancy Complications, Cardiovascular	11.6%
120	Polycystic Kidney Diseases	11.5%
121	Kounis Syndrome	11.5%
122	Angina Pectoris	11.3%
123	Adams-Stokes Syndrome	11.2%
124	Atrioventricular Block	11.2%
125	Bundle-Branch Block	11.2%
126	Coronary Thrombosis	11.2%
127	Atrial Premature Complexes	11.2%
128	Sinoatrial Block	11.2%
129	Tachycardia, Paroxysmal	11.2%
130	Supraventricular tachycardia	11.2%
131	Tachycardia, Ventricular	11.2%
132	Tachycardia, Reciprocating	11.2%
133	Coronary Artery Disease	11.2%
134	Acrocephalosyndactylia	11%
135	Microcephaly	11%
136	Macrocephaly	11%
137	Fetal Diseases	11%
138	Craniosynostosis	10.9%
139	Syndactyly	10.9%
140	Brachycephaly	10.9%
141	Pseudoxanthoma Elasticum	10.9%
142	Fragile X Syndrome	10.8%
143	Dextrocardia	10.7%
144	Aortic Valve Insufficiency	10.6%
145	Restrictive cardiomyopathy	10.6%
146	Endocardial Fibroelastosis	10.6%
147	Heart Rupture, Post-Infarction	10.6%
148	Mitral Valve Insufficiency	10.6%
149	Mitral Valve Stenosis	10.6%
150	Myocarditis	10.6%
151	Pericarditis, Constrictive	10.6%
152	Pulmonary Valve Insufficiency	10.6%
153	Tricuspid Valve Insufficiency	10.6%
154	Tricuspid Valve Stenosis	10.6%
155	Ventricular Dysfunction, Left	10.6%
156	Right Ventricular Dysfunction	10.6%
157	Endomyocardial Fibrosis	10.6%
158	Carditis	10.6%
159	Heart Failure, Systolic	10.6%
160	Heart Failure, Diastolic	10.6%
161	Retinal Dysplasia	10.6%
162	Aniridia	10.5%
163	Ichthyosis, X-Linked	10.4%
164	Epidermolysis Bullosa	10.3%
165	Blepharophimosis	10.1%
166	Laryngostenosis	10.1%
167	Mouth Abnormalities	10.1%
168	Smith-Lemli-Opitz Syndrome	10.1%
169	Situs Inversus	10.1%
170	Esophageal Atresia	10%
171	Intestinal Atresia	10%
172	Horseshoe Kidney	10%
173	Pectus excavatum	10%
174	Klippel-Feil Syndrome	10%
175	Gastroschisis	10%
176	Synostosis	10%
177	Acrodermatitis	10%
178	Lymphangiectasis, Intestinal	10%
179	Gianotti-Crosti Syndrome	10%
180	Classical Lissencephalies and Subcortical Band Heterotopias	9.9%
181	Coronary Occlusion	9.8%
182	Microvascular Angina	9.8%
183	Coronary Stenosis	9.8%
184	ST segment elevation myocardial infarction	9.8%
185	Carcinoid Heart Disease	9.8%
186	Porencephaly	9.8%
187	Primary Ciliary Dyskinesia	9.6%
188	Cystic Fibrosis	9.4%
189	Cleft Palate	9.4%
190	Tachycardia, Atrioventricular Nodal Reentry	9.3%
191	Tachycardia, Ectopic Atrial	9.3%
192	Tachycardia, Ectopic Junctional	9.3%
193	Sinus Tachycardia	9.3%
194	Torsades de Pointes	9.3%
195	Accelerated Idioventricular Rhythm	9.3%
196	Jaw Abnormalities	9%
197	Arthrogryposis	8.9%
198	Choanal Atresia	8.9%
199	Tracheobronchomegaly	8.9%
200	Laryngocele	8.9%
201	Choledochal Cyst	8.9%
202	Hermaphroditism	8.9%
203	Disorders of Sex Development	8.9%
204	Aortic Aneurysm	8.8%
205	Aortitis	8.8%
206	Sinus Arrhythmia	8.8%
207	Atrial Fibrillation	8.8%
208	Atrial Flutter	8.8%
209	Edema, Cardiac	8.8%
210	Leriche Syndrome	8.8%
211	Periphlebitis	8.8%
212	Phlebitis	8.8%
213	Thromboangiitis Obliterans	8.8%
214	Ventricular Fibrillation	8.8%
215	Ventricular Flutter	8.8%
216	Parasystole	8.8%
217	Paroxysmal atrial fibrillation	8.8%
218	Bradycardia	8.8%
219	Diabetic Cardiomyopathies	8.8%
220	Cardiomyopathy, Alcoholic	8.8%
221	Sudden Cardiac Death	8.8%
222	Left Ventricular Hypertrophy	8.8%
223	Right Ventricular Hypertrophy	8.8%
224	Cryptorchidism	8.8%
225	Hypospadias	8.8%
226	Chagas Cardiomyopathy	8.8%
227	Central Nervous System Cysts	8.7%
228	Dandy-Walker Syndrome	8.7%
229	POEMS Syndrome	8.6%
230	Poland Syndrome	8.6%
231	Embolism, Amniotic Fluid	8.6%
232	Shock, Cardiogenic	8.5%
233	Angina, Unstable	8.4%
234	Meconium Aspiration Syndrome	8.3%
235	Sjogren-Larsson Syndrome	8.3%
236	Klinefelter Syndrome	8.3%
237	Amelia	8.2%
238	Arachnodactyly	8.2%
239	Ectromelia	8.2%
240	Hemimelia	8.2%
241	Meningomyelocele	8.2%
242	Phocomelia	8.2%
243	Sirenomelia	8.2%
244	Spina Bifida	8.2%
245	Polydactyly	8.2%
246	Brachydactyly	8.2%
247	Plagiocephaly	8.2%
248	Lower Extremity Deformities, Congenital	8.2%
249	Upper Extremity Deformities, Congenital	8.2%
250	Retinal Vein Occlusion	8.2%
251	Coronary Restenosis	8.2%
252	Polycystic Kidney, Autosomal Dominant	8.1%
253	Aneurysm	8.1%
254	Angiomatosis	8.1%
255	Aortic Diseases	8.1%
256	Arterial Occlusive Diseases	8.1%
257	Hyperemia	8.1%
258	Hypotension	8.1%
259	Superior Vena Cava Syndrome	8.1%
260	Telangiectasis	8.1%
261	Vasculitis	8.1%
262	Venous Insufficiency	8.1%
263	Peripheral Vascular Diseases	8.1%
264	Embolism and Thrombosis	8.1%
265	Angiodysplasia	8.1%
266	Capillary Leak Syndrome	8.1%
267	Prehypertension	8.1%
268	Thrombophlebitis	7.9%
269	Laryngomalacia	7.9%
270	Aortic Valve Prolapse	7.9%
271	Tricuspid Valve Prolapse	7.9%
272	Takotsubo Cardiomyopathy	7.9%
273	Pectus carinatum	7.9%
274	Angioedemas, Hereditary	7.9%
275	Xeroderma Pigmentosum	7.8%
276	Bladder Exstrophy	7.8%
277	Epispadias	7.8%
278	Multicystic Dysplastic Kidney	7.7%
279	Postphlebitic Syndrome	7.7%
280	Malignant Atrophic Papulosis	7.6%
281	Kallmann Syndrome	7.6%
282	Dyspnea, Paroxysmal	7.5%
283	Shwartzman Phenomenon	7.5%
284	Aortic Rupture	7.4%
285	Abdominal Cramps	7.4%
286	Amniotic Band Syndrome	7.4%
287	Asphyxia Neonatorum	7.4%
288	Infant, Premature, Diseases	7.4%
289	Infantile Colic	7.4%
290	Micrognathism	7.3%
291	Pierre Robin Syndrome	7.3%
292	Subacute Bacterial Endocarditis	7.3%
293	Zellweger Syndrome	7.3%
294	Charcot-Marie-Tooth Disease	7.3%
295	Antley-Bixler Syndrome Phenotype	7.3%
296	Hyperkeratosis, Epidermolytic	7.1%
297	Basal Cell Nevus Syndrome	7.1%
298	Dental Enamel Hypoplasia	7.1%
299	Hypodontia	7.1%
300	Macrostomia	7.1%
301	Meningocele	7.1%
302	Microstomia	7.1%
303	Encephalocele	7.1%
304	Craniofacial Dysostosis	7%
305	Angina Pectoris, Variant	6.9%
306	Vascular System Injuries	6.9%
307	Carotid Artery Thrombosis	6.9%
308	Heart Diseases	6.9%
309	Moyamoya Disease	6.9%
310	Blue Toe Syndrome	6.8%
311	Compartment syndromes	6.8%
312	Hepatic Veno-Occlusive Disease	6.8%
313	Peliosis Hepatis	6.8%
314	Varicocele	6.8%
315	Tuberous Sclerosis	6.7%
316	Cerebrovascular Disorders	6.7%
317	Diabetic Angiopathies	6.7%
318	Reperfusion Injury	6.7%
319	Splenic Infarction	6.7%
320	Cerebrovascular Insufficiency	6.7%
321	Vascular Neoplasms	6.7%
322	Spinal Cord Vascular Diseases	6.7%
323	Vasoplegia	6.7%
324	Retrognathia	6.7%
325	Hemorrhoids	6.7%
326	Thoracic Outlet Syndrome	6.7%
327	Intracranial Embolism and Thrombosis	6.6%
328	Carotid Stenosis	6.6%
329	Intracranial Aneurysm	6.6%
330	Aortic Aneurysm, Abdominal	6.6%
331	Aortic Aneurysm, Thoracic	6.6%
332	Sinus Arrest, Cardiac	6.6%
333	Dermal Sinus	6.5%
334	Spina Bifida Cystica	6.5%
335	Spina Bifida Occulta	6.5%
336	Lissencephaly	6.5%
337	Polymicrogyria	6.5%
338	Pachygyria	6.5%
339	Schizencephaly	6.5%
340	Periventricular Nodular Heterotopia	6.5%
341	Refsum Disease	6.5%
342	Hyperandrogenism	6.5%
343	Neoplastic Syndromes, Hereditary	6.4%
344	Platybasia	6.2%
345	Gonadal Dysgenesis	6.2%
346	Leukomalacia, Periventricular	6.2%
347	Bronchomalacia	6.2%
348	Adrenogenital Syndrome	6.2%
349	Tracheomalacia	6.2%
350	Ovotesticular Disorders of Sex Development	6.2%
351	Anemia, Neonatal	6.1%
352	Multiple Epiphyseal Dysplasia	6.1%
353	Osteochondrodysplasias	6.1%
354	Pelger-Huet Anomaly	6.1%
355	Persistent Fetal Circulation Syndrome	6.1%
356	Werner Syndrome	6.1%
357	Myasthenic Syndromes, Congenital	6.1%
358	Prognathism	6.1%
359	Umbilical hernia	6.1%
360	Vasculitis, Central Nervous System	5.9%
361	Hand-Arm Vibration Syndrome	5.9%
362	Optic Neuropathy, Ischemic	5.8%
363	Anterior Ischemic Optic Neuropathy	5.8%
364	Mesenteric vascular insufficiency	5.8%
365	Ataxia Telangiectasia	5.8%
366	Anemia, Sickle Cell	5.8%
367	Thalassemia	5.8%
368	Muscular Dystrophy, Duchenne	5.7%
369	Albinism	5.7%
370	Angioedema	5.7%
371	Colitis, Ischemic	5.7%
372	Polyarteritis Nodosa	5.6%
373	Takayasu Arteritis	5.6%
374	Intracranial Arteriosclerosis	5.6%
375	Cerebral Atherosclerosis	5.6%
376	Cerebral Arteriosclerosis	5.6%
377	Dwarfism	5.4%
378	Neonatal Abstinence Syndrome	5.4%
379	Giant Cell Arteritis	5.3%
380	Temporal Arteritis	5.3%
381	Aneurysm, Dissecting	5.3%
382	Arteriosclerosis	5.3%
383	Arteritis	5.3%
384	Embolism	5.3%
385	Erythromelalgia	5.3%
386	Fibromuscular Dysplasia	5.3%
387	Malignant Hypertension	5.3%
388	Raynaud Disease	5.3%
389	Thromboembolism	5.3%
390	Thrombosis	5.3%
391	Essential Hypertension	5.3%
392	Aneurysm, Ruptured	5.3%
393	Iliac Aneurysm	5.3%
394	Pulmonary artery stenosis	5.3%
395	White Coat Hypertension	5.3%
396	Systemic Vasculitis	5.3%
397	Embolus	5.3%
398	Fetal Growth Retardation	5.3%
399	Muscular Dystrophy	5.2%
400	Osteogenesis Imperfecta	5.2%
401	Fetal Hypoxia	5.2%
402	Congenital nystagmus	5.2%
403	Fetal Alcohol Spectrum Disorders	5.2%
404	Toxoplasmosis, Congenital	5.2%
405	Syphilis, Congenital	5.2%
406	Cerebral Thrombosis	5.1%
407	Intracranial Embolism	5.1%
408	Intracranial Thrombosis	5.1%
409	Behcet Syndrome	5%
410	Mandibulofacial Dysostosis	4.9%
411	Brain Infarction	4.9%
412	Goldenhar Syndrome	4.9%
413	Mucopolysaccharidosis II	4.8%
414	Lemierre Syndrome	4.8%
415	Fabry Disease	4.7%
416	Subarachnoid Hemorrhage, Traumatic	4.7%
417	Carotid Artery, Internal, Dissection	4.7%
418	Rett Syndrome	4.7%
419	Autoimmune Lymphoproliferative Syndrome	4.6%
420	Menkes Kinky Hair Syndrome	4.6%
421	Familial Mediterranean Fever	4.6%
422	Wiskott-Aldrich Syndrome	4.6%
423	Congenital Hyperinsulinism	4.6%
424	Chorioamnionitis	4.6%
425	CREST Syndrome	4.6%
426	Infarction, Middle Cerebral Artery	4.5%
427	Infarction, Anterior Cerebral Artery	4.5%
428	Infarction, Posterior Cerebral Artery	4.5%
429	Retinal Artery Occlusion	4.5%
430	Retinal Vasculitis	4.5%
431	Hypertensive Retinopathy	4.5%
432	Anterior Compartment Syndrome	4.4%
433	Vasculitis, Leukocytoclastic, Cutaneous	4.4%
434	Gastric Antral Vascular Ectasia	4.4%
435	Abdominal Compartment Syndrome	4.4%
436	Sinus Thrombosis, Intracranial	4.4%
437	Carotid Artery Diseases	4.4%
438	Brain Ischemia	4.4%
439	Hypotension, Orthostatic	4.4%
440	Cerebrovascular accident	4.4%
441	Varicose Ulcer	4.4%
442	Vasospasm, Intracranial	4.4%
443	Spinal Cord Ischemia	4.4%
444	Intracranial Arterial Diseases	4.4%
445	Primary Graft Dysfunction	4.4%
446	Post-Exercise Hypotension	4.4%
447	Vertebral Artery Dissection	4.4%
448	Talipes	4.3%
449	Myotonic Dystrophy	4.2%
450	Sickle Cell Trait	4.1%
451	Cavernous Sinus Thrombosis	4%
452	Sagittal Sinus Thrombosis	4%
453	Cerebral Infarction	4%
454	Brain Stem Infarctions	4%
455	Neuronal Ceroid-Lipofuscinoses	4%
456	Congenital clubfoot	4%
457	Vertical Talus	4%
458	Arteriosclerosis Obliterans	3.9%
459	Atherosclerosis	3.9%
460	Air Embolism	3.9%
461	Endarteritis	3.9%
462	Venous Thrombosis	3.9%
463	Deep Vein Thrombosis	3.9%
464	Venous Thromboembolism	3.9%
465	Carotid Artery Injuries	3.9%
466	Paralysis, Obstetric	3.9%
467	Retinopathy of Prematurity	3.9%
468	Adrenoleukodystrophy	3.9%
469	Amino Acid Metabolism, Inborn Errors	3.9%
470	Carbohydrate Metabolism, Inborn Errors	3.9%
471	Metal Metabolism, Inborn Errors	3.9%
472	Progeria	3.9%
473	Lysosomal Storage Diseases	3.9%
474	Cytochrome-c Oxidase Deficiency	3.9%
475	Peroxisomal Disorders	3.9%
476	Bronchopulmonary Dysplasia	3.8%
477	Mesenteric Vascular Occlusion	3.8%
478	Mucocutaneous Lymph Node Syndrome	3.8%
479	Diabetic Retinopathy	3.8%
480	Sturge-Weber Syndrome	3.8%
481	Livedo Reticularis	3.8%
482	Renal hypertension	3.8%
483	Renal Artery Obstruction	3.8%
484	Renal Artery Stenosis	3.8%
485	Hemangioma, Cavernous	3.8%
486	Basal Ganglia Cerebrovascular Disease	3.8%
487	Vascular Headaches	3.7%
488	Scurvy	3.7%
489	Hepatolenticular Degeneration	3.7%
490	Kearns-Sayre syndrome	3.7%
491	Lateral Medullary Syndrome	3.6%
492	Ophthalmia Neonatorum	3.6%
493	Amyloid Neuropathies, Familial	3.6%
494	Basal Ganglia Hemorrhage	3.6%
495	Denys-Drash Syndrome	3.4%
496	Respiratory Distress Syndrome, Newborn	3.4%
497	Cutis Laxa	3.3%
498	Intermittent Claudication	3.3%
499	Pulmonary Embolism	3.3%
500	Retinitis Pigmentosa	3.3%
501	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3.3%
502	Pigmentary retinopathy	3.3%
503	Ischemic contracture	3.3%
504	Porokeratosis	3.3%
505	Keratoderma, Palmoplantar	3.3%
506	Acute Chest Syndrome	3.3%
507	Hydrops Fetalis	3.3%
508	Chronic granulomatous disease	3.3%
509	No-Reflow Phenomenon	3.3%
510	Cryoglobulinemia	3.3%
511	Welander Distal Myopathy	3.3%
512	Diabetic Foot	3.3%
513	Cerebral Arterial Diseases	3.3%
514	Vertebrobasilar Insufficiency	3.3%
515	Anterior Spinal Artery Syndrome	3.3%
516	Basilar Artery Stenosis	3.3%
517	Vertebral Artery Stenosis	3.3%
518	Intracranial Hemorrhage, Hypertensive	3.3%
519	Transient Cerebral Ischemia	3.3%
520	Galactosemias	3.3%
521	Urea Cycle Disorders, Inborn	3.3%
522	Tyrosinemias	3.3%
523	Glycogen storage disease type II	3.2%
524	Putaminal Hemorrhage	3.1%
525	Canavan Disease	3%
526	Alexander Disease	3%
527	Optic Atrophy, Hereditary, Leber	3%
528	Hyperphosphaturia	3%
529	Duane Retraction Syndrome	3%
530	Dementia, Vascular	3%
531	Porphyrias, Hepatic	2.9%
532	Shy-Drager Syndrome	2.9%
533	Purpura, Hyperglobulinemic	2.9%
534	Peutz-Jeghers Syndrome	2.9%
535	Myotonia Congenita	2.9%
536	Thrombasthenia	2.9%
537	Antithrombin III Deficiency	2.9%
538	Protein C Deficiency	2.9%
539	Brain Diseases, Metabolic, Inborn	2.9%
540	Afibrinogenemia	2.9%
541	Dystonia Musculorum Deformans	2.9%
542	Factor VII Deficiency	2.9%
543	Factor X Deficiency	2.9%
544	Factor XII Deficiency	2.9%
545	Hemophilia A	2.9%
546	Activated Protein C Resistance	2.9%
547	Factor II deficiency	2.9%
548	Factor VIII Deficiency	2.9%
549	Factor V deficiency	2.9%
550	Factor XI Deficiency	2.9%
551	Hypoprothrombinemias	2.9%
552	Mucopolysaccharidosis III	2.9%
553	Fanconi Anemia	2.9%
554	Nesidioblastosis	2.9%
555	Lafora Disease	2.9%
556	Unverricht-Lundborg Syndrome	2.9%
557	Anemia, Diamond-Blackfan	2.9%
558	Hypertension, Renovascular	2.8%
559	Subarachnoid Hemorrhage	2.8%
560	Hypoxia-Ischemia, Brain	2.8%
561	Cerebral Hemorrhage	2.8%
562	Hereditary Angioedema Type III	2.8%
563	Hereditary Angioedema Types I and II	2.8%
564	Hepatic Vein Thrombosis	2.8%
565	Budd-Chiari Syndrome	2.8%
566	Pulmonary Infarction	2.7%
567	MELAS Syndrome	2.7%
568	Alkaptonuria	2.7%
569	Glycogen Storage Disease	2.7%
570	Hypophosphatasia	2.7%
571	Propionic acidemia	2.7%
572	Dihydropyrimidine Dehydrogenase Deficiency	2.7%
573	Cystinosis	2.7%
574	Subclavian Steal Syndrome	2.7%
575	Homocystinuria	2.7%
576	Leigh Disease	2.7%
577	Multiple Endocrine Neoplasia	2.6%
578	Waldenstrom Macroglobulinemia	2.6%
579	Multiple Myeloma	2.6%
580	Lupus Vasculitis, Central Nervous System	2.6%
581	Congenital Hypothyroidism	2.6%
582	Dermatitis, Atopic	2.6%
583	Gaucher Disease	2.6%
584	Pituitary Apoplexy	2.5%
585	Hyaline Membrane Disease	2.4%
586	Granulomatosis with polyangiitis	2.4%
587	Carbamoyl-Phosphate Synthase I Deficiency Disease	2.4%
588	Hypolipoproteinemias	2.3%
589	Papillon-Lefevre Disease	2.3%
590	Kernicterus	2.3%
591	Hyperlipidemia, Familial Combined	2.3%
592	Hyperlipoproteinemia Type III	2.3%
593	Cerebral Amyloid Angiopathy	2.3%
594	Tay-Sachs Disease	2.3%
595	Niemann-Pick Disease, Type C	2.2%
596	Rheumatoid Vasculitis	2.2%
597	Glycogen Storage Disease Type I	2.2%
598	Glycogen Storage Disease Type V	2.2%
599	Huntington Disease	2.1%
600	Familial Periodic Paralysis	2.1%
601	Lactose Intolerance	2%
602	Variegate Porphyria	2%
603	Acute intermittent porphyria	2%
604	Porphyria Cutanea Tarda	2%
605	Hyperhomocysteinemia	2%
606	Renal Aminoacidurias	2%
607	Fanconi Syndrome	2%
608	Pseudohypoaldosteronism	2%
609	Liddle Syndrome	2%
610	Hyperlipoproteinemia Type IV	2%
611	Hyperlipoproteinemia Type V	2%
612	Nephroblastoma	1.9%
613	Hypoalphalipoproteinemias	1.9%
614	Gout	1.8%
615	Multiple Endocrine Neoplasia Type 1	1.8%
616	Pseudohypoparathyroidism	1.8%
617	Friedreich Ataxia	1.8%
618	Renal tubular acidosis	1.8%
619	Adenomatous Polyposis Coli	1.8%
620	Hypokalemic periodic paralysis	1.6%
621	Hematoma, Subdural	1.6%
622	Hematoma, Epidural, Cranial	1.6%
623	Cystinuria	1.6%
624	Familial Hypophosphatemic Rickets	1.6%
625	Glycosuria, Renal	1.5%
626	Brain Hemorrhage, Traumatic	1.5%
627	Arthritis, Gouty	1.4%
628	Hematoma, Subdural, Intracranial	1.4%
629	Hematoma, Subdural, Chronic	1.4%
630	Hematoma, Subdural, Acute	1.4%

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