MetaADEDB 2.0 @ LMMD
zaleplon
(HUNXMJYCHXQEGX-UHFFFAOYSA-N)
Structure
SMILES
CCN(c1cccc(c1)c1ccnc2n1ncc2C#N)C(=O)C
Type(s)
Approved; Illicit; Investigational
ATC code(s)
N05CF03
Molecular Formula:
C17H15N5O
Molecular Weight:
305.334
Log P:
2.6408
Hydrogen Bond Acceptor:
6
Hydrogen Bond Donor:
0
TPSA:
74.29
CAS Number(s):
151319-34-5
Synonym(s)
1.
zaleplon
2.
3'-(3-cyanopyrazolo(1,5-alpha)pyrimidin-7-yl)-N-ethylacetanilide
3.
CL 284,846
4.
CL 284846
5.
CL-284846
6.
CL284,846
7.
L 846
8.
L-846
9.
N-(3-(3-cyanopyrazolo(1,5-a)pyrimidin-7-yl)phenyl)-N-ethylacetamide
10.
SKP-1041
11.
Sonata
12.
Starnoc
13.
Zelepion
External Link(s)
MeSHC085665
PubChem Compound5719
BindingDB86521
ChEBI10102
CHEMBLCHEMBL1521
DrugBankDB00962
DrugCentral2857
IUPHAR/BPS Guide to PHARMACOLOGY4345
KEGGcpd:C07484
dr:D00530
Therapeutic Target DatabaseD09DWL
ZINC6300
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 121OFFSIDES
US FAERS
2Middle insomniaFAERS: 17OFFSIDES
US FAERS
3HeadacheFAERS: 12SIDER
US FAERS
4SomnolenceFAERS: 12SIDER
US FAERS
5DizzinessFAERS: 11OFFSIDES
SIDER
US FAERS
6OverdoseFAERS: 11US FAERS
7NauseaFAERS: 10OFFSIDES
SIDER
US FAERS
8Product substitution issueFAERS: 10US FAERS
9SomnambulismFAERS: 10SIDER
US FAERS
10AmnesiaFAERS: 9OFFSIDES
SIDER
US FAERS
11Product quality issueFAERS: 8US FAERS
12FatigueFAERS: 7OFFSIDES
US FAERS
13Feeling abnormalFAERS: 7SIDER
US FAERS
14VomitingFAERS: 7US FAERS
15Poor quality sleepFAERS: 6OFFSIDES
US FAERS
16HypersomniaFAERS: 5US FAERS
17MalaiseFAERS: 5SIDER
US FAERS
18Suicide attemptFAERS: 5US FAERS
19AstheniaFAERS: 4OFFSIDES
SIDER
US FAERS
20ChromaturiaFAERS: 4OFFSIDES
US FAERS
21Drug abuseFAERS: 4US FAERS
22MyoclonusFAERS: 4SIDER
US FAERS
23NervousnessFAERS: 4SIDER
US FAERS
24Sinus TachycardiaFAERS: 4US FAERS
25AgitationFAERS: 3SIDER
US FAERS
26AnxietyFAERS: 3OFFSIDES
SIDER
US FAERS
27Drug effect incompleteFAERS: 3US FAERS
28DysarthriaFAERS: 3SIDER
US FAERS
29Euphoric moodFAERS: 3SIDER
US FAERS
30Intentional misuseFAERS: 3US FAERS
31PallorFAERS: 3US FAERS
32PruritusFAERS: 3SIDER
US FAERS
33RestlessnessFAERS: 3US FAERS
34TachycardiaFAERS: 3SIDER
US FAERS
35Blood creatine phosphokinase increasedFAERS: 2US FAERS
36Depressed Level of ConsciousnessFAERS: 2SIDER
US FAERS
37DisorientationFAERS: 2US FAERS
38Drug DependenceFAERS: 2US FAERS
39Drug ToleranceFAERS: 2US FAERS
40Drug abuserFAERS: 2US FAERS
41DysgeusiaFAERS: 2OFFSIDES
SIDER
US FAERS
42Elevated moodFAERS: 2US FAERS
43HypersensitivityFAERS: 2US FAERS
44HypotensionFAERS: 2SIDER
US FAERS
45Incorrect route of drug administrationFAERS: 2US FAERS
46Initial insomniaFAERS: 2US FAERS
47LeukocytosisFAERS: 2SIDER
US FAERS
48Lip swellingFAERS: 2US FAERS
49Mental status changesFAERS: 2OFFSIDES
US FAERS
50PalpitationsFAERS: 2SIDER
US FAERS
51Paradoxical drug reactionFAERS: 2US FAERS
52ParanoiaFAERS: 2US FAERS
53TremorFAERS: 2SIDER
US FAERS
54UrticariaFAERS: 2SIDER
US FAERS
55Victim of sexual abuseFAERS: 2US FAERS
56Visual disturbanceFAERS: 2OFFSIDES
US FAERS
57Abnormal sleep-related eventFAERS: 1US FAERS
58Accidental exposureFAERS: 1US FAERS
59Adverse eventFAERS: 1OFFSIDES
US FAERS
60AnorgasmiaFAERS: 1US FAERS
61ArthralgiaFAERS: 1SIDER
US FAERS
62Burning sensationFAERS: 1US FAERS
63Chest PainFAERS: 1OFFSIDES
SIDER
US FAERS
64Dreamy stateFAERS: 1US FAERS
65Drug administration errorFAERS: 1US FAERS
66Drug diversionFAERS: 1US FAERS
67Drug ineffective for unapproved indicationFAERS: 1US FAERS
68Drug screen false positiveFAERS: 1US FAERS
69Drug toxicityFAERS: 1OFFSIDES
US FAERS
70DyslexiaFAERS: 1US FAERS
71Ear discomfortFAERS: 1US FAERS
72Eye painFAERS: 1SIDER
US FAERS
73Feeling jitteryFAERS: 1US FAERS
74FibromyalgiaFAERS: 1OFFSIDES
US FAERS
75FlatulenceFAERS: 1SIDER
US FAERS
76Hormone level abnormalFAERS: 1US FAERS
77HypervigilanceFAERS: 1US FAERS
78Impaired work abilityFAERS: 1US FAERS
79ImpatienceFAERS: 1US FAERS
80Intentional drug misuseFAERS: 1OFFSIDES
US FAERS
81Limb injuryFAERS: 1US FAERS
82MydriasisFAERS: 1US FAERS
83No adverse drug reactionFAERS: 1US FAERS
84NocturiaFAERS: 1US FAERS
85PregnancyFAERS: 1US FAERS
86Premenstrual Dysphoric DisorderFAERS: 1US FAERS
87Premenstrual syndromeFAERS: 1US FAERS
88Product physical issueFAERS: 1US FAERS
89Pulmonary HypertensionFAERS: 1OFFSIDES
US FAERS
90Pupillary light reflex tests abnormalFAERS: 1US FAERS
91Reaction to drug excipientsFAERS: 1US FAERS
92Renal painFAERS: 1SIDER
US FAERS
93Respiratory DepressionFAERS: 1US FAERS
94Restless Legs SyndromeFAERS: 1US FAERS
95Sleep TalkingFAERS: 1OFFSIDES
SIDER
US FAERS
96Sleep-related eating disorderFAERS: 1US FAERS
97TinnitusFAERS: 1SIDER
US FAERS
98Tooth ErosionFAERS: 1US FAERS
99Urinary IncontinenceFAERS: 1SIDER
US FAERS
100VertigoFAERS: 1SIDER
US FAERS
101Visual ImpairmentFAERS: 1SIDER
US FAERS
102Wrong technique in drug usage processFAERS: 1US FAERS
103treatment failureFAERS: 1US FAERS
104Abdominal InfectionOFFSIDES
105Abdominal PainOFFSIDES
SIDER
106Abdominal discomfortOFFSIDES
107Abdominal hernia obstructiveOFFSIDES
108Abnormal visionSIDER
109AbscessOFFSIDES
110AbuseOFFSIDES
111Acid refluxOFFSIDES
112AcneOFFSIDES
113Activities of daily living impairedOFFSIDES
114AgeusiaSIDER
115AgraphiaOFFSIDES
116Alanine Aminotransferase IncreasedSIDER
117AlbuminuriaSIDER
118AlopeciaOFFSIDES
SIDER
119AlveolitisOFFSIDES
120Anaphylactic shockSIDER
121Anaphylactoid ReactionSIDER
122Anastomotic complicationOFFSIDES
123AngerOFFSIDES
SIDER
124Angina PectorisSIDER
125AngioedemaSIDER
126AnhedoniaOFFSIDES
127AnhidrosisOFFSIDES
128AnorexiaSIDER
129Anoxic EncephalopathyOFFSIDES
130Antiviral drug level above therapeuticOFFSIDES
131ApathySIDER
132Aphthous StomatitisOFFSIDES
SIDER
133ApneaOFFSIDES
134ArthritisSIDER
135ArthropathyOFFSIDES
SIDER
136Aspartate Aminotransferase IncreasedSIDER
137AsthmaSIDER
138AstigmatismOFFSIDES
139Asymptomatic bacteriuriaOFFSIDES
140AtaxiaSIDER
141AtelectasisOFFSIDES
142AuraOFFSIDES
143Auricular swellingOFFSIDES
144Back PainSIDER
145Band neutrophil percentage increasedOFFSIDES
146BereavementOFFSIDES
147Bile Duct StenosisOFFSIDES
148Biliary ColicSIDER
149BilirubinuriaOFFSIDES
150Biopsy muscle abnormalOFFSIDES
151Bipolar DisorderOFFSIDES
152Bladder painSIDER
153BlepharitisSIDER
154BlepharospasmOFFSIDES
155Blood GlucoseOFFSIDES
156Blood albumin decreasedOFFSIDES
157Blood chloride decreasedOFFSIDES
158Blood cholesterolOFFSIDES
159Blood glucose decreasedOFFSIDES
160Blood immunoglobulin G increasedOFFSIDES
161Blood sodiumOFFSIDES
162Blood triglycerides increasedOFFSIDES
163Blurred visionOFFSIDES
164BradycardiaOFFSIDES
165BronchitisOFFSIDES
SIDER
166BruxismOFFSIDES
SIDER
167BursitisOFFSIDES
SIDER
168Carotid bruitOFFSIDES
169Cataract specifiedSIDER
170CataractSIDER
171Catheter site infectionOFFSIDES
172CellulitisOFFSIDES
173Central nervous system lesionOFFSIDES
174Cerebellar infarctionOFFSIDES
175Cerebral ventricle dilatationOFFSIDES
176Cervical polypOFFSIDES
177Cervicobrachial syndromeOFFSIDES
178CheilitisSIDER
179ChillsSIDER
180Choking sensationOFFSIDES
181CholelithiasisSIDER
182Chronic Obstructive Airway DiseaseOFFSIDES
183Chronic left ventricular failureOFFSIDES
184Chronic ulcerative colitisOFFSIDES
185Circumoral paresthesiaSIDER
186CirrhosisOFFSIDES
187ColitisSIDER
188Completed SuicideOFFSIDES
189ConfabulationOFFSIDES
190Congenital HypothyroidismOFFSIDES
191Congenital heart diseaseOFFSIDES
192Congenital tricuspid valve incompetenceOFFSIDES
193ConjunctivitisSIDER
194ConstipationSIDER
195Corneal erosionSIDER
196CyanosisOFFSIDES
SIDER
197CystitisSIDER
198CystOFFSIDES
199DeafnessOFFSIDES
SIDER
200DehydrationOFFSIDES
201DemyelinationOFFSIDES
202DependenceOFFSIDES
SIDER
203Depression suicidalOFFSIDES
204DermatitisSIDER
205DiabetesOFFSIDES
206Diabetes MellitusSIDER
207Diabetes mellitus inadequate controlOFFSIDES
208DiplopiaOFFSIDES
SIDER
209DiscomfortSIDER
210Disturbance in sexual arousalSIDER
211DiverticulumOFFSIDES
212DrowningOFFSIDES
213DrowsinessOFFSIDES
214Drug addictOFFSIDES
215Drug exposure during pregnancyOFFSIDES
216Drug withdrawal headacheOFFSIDES
217Dry skinSIDER
218Duodenal UlcerSIDER
219DysgraphiaOFFSIDES
220DyspepsiaOFFSIDES
SIDER
221DysphemiaOFFSIDES
222Dysthymic DisorderOFFSIDES
223DysuriaSIDER
224Ear and labyrinth disordersSIDER
225Ear dischargeOFFSIDES
226EcchymosisSIDER
227Economic problemOFFSIDES
228EczemaSIDER
229Electrocardiogram ST-T changeOFFSIDES
230Emotional disorderOFFSIDES
231Emotional distressOFFSIDES
232EndocarditisOFFSIDES
233EnteritisSIDER
234Eosinophil percentage increasedOFFSIDES
235EosinophiliaSIDER
236EpistaxisOFFSIDES
SIDER
237Erectile dysfunctionSIDER
238EructationSIDER
239ErythemaOFFSIDES
240Facial paralysisSIDER
241Failure to ThriveOFFSIDES
242Fatty LiverOFFSIDES
243Flank PainOFFSIDES
244Flat affectSIDER
245GamblingOFFSIDES
246GastritisSIDER
247GastroenteritisSIDER
248Gastrointestinal PainSIDER
249GingivitisSIDER
250GlaucomaSIDER
251GlossitisSIDER
252GoutSIDER
253Grip strengthOFFSIDES
254HepatotoxicitySIDER
255HostilitySIDER
256HyperacusisSIDER
257HyperkeratosisOFFSIDES
258HyperkinesiaSIDER
259HyperreflexiaSIDER
260HyperventilationOFFSIDES
SIDER
261HypokinesiaSIDER
262HyporeflexiaSIDER
263HypothyroidismSIDER
264HypoxiaOFFSIDES
265Impaired driving abilityOFFSIDES
266Increased bronchial secretionSIDER
267Injection site infectionOFFSIDES
268Intention tremorOFFSIDES
269Intervertebral disc disorderOFFSIDES
270Intestinal ObstructionSIDER
271Joint Range of Motion DecreasedOFFSIDES
272Joint sprainOFFSIDES
273Keratitis siccaOFFSIDES
274KetosisSIDER
275LabyrinthitisSIDER
276Lactose IntoleranceSIDER
277LaryngitisSIDER
278LeukorrheaSIDER
279Lung hyperinflationOFFSIDES
280LymphadenopathySIDER
281Lymphocyte percentage decreasedOFFSIDES
282LymphocytosisSIDER
283MalnutritionSIDER
284MelanosisSIDER
285MenopauseSIDER
286MenorrhagiaSIDER
287Mental impairmentOFFSIDES
288Metabolic acidosisOFFSIDES
289MetrorrhagiaSIDER
290Mood swingsSIDER
291Movement Disorders8905326CTD
292Multiple SclerosisOFFSIDES
293Multiple sclerosis relapseOFFSIDES
294Muscle relaxant therapySIDER
295Muscle strainOFFSIDES
296Muscle tightnessOFFSIDES
297Musculoskeletal PainOFFSIDES
298Musculoskeletal chest painOFFSIDES
299Musculoskeletal discomfortOFFSIDES
SIDER
300Musculoskeletal stiffnessOFFSIDES
SIDER
301MyalgiaSIDER
302MyopiaOFFSIDES
303MyositisSIDER
304Neck stiffnessSIDER
305NephrolithiasisSIDER
306Nerve Root CompressionOFFSIDES
307NeuralgiaOFFSIDES
SIDER
308Neuroleptic Malignant SyndromeOFFSIDES
309NeuropathySIDER
310Neuropsychological test abnormalOFFSIDES
311Non-cardiac chest painOFFSIDES
312Nuchal RigiditySIDER
313NystagmusSIDER
314Obsessive thoughtsOFFSIDES
315OsteoporosisSIDER
316PainOFFSIDES
SIDER
317Pancreatic Duct StenosisOFFSIDES
318PancreatitisOFFSIDES
319Panic DisorderOFFSIDES
320Pathogen resistanceOFFSIDES
321Peptic UlcerSIDER
322PeriarthritisOFFSIDES
323Pericardial effusionSIDER
324Pharyngolaryngeal PainOFFSIDES
325PhotophobiaSIDER
326PneumoniaSIDER
327PolyneuropathyOFFSIDES
328Poor peripheral circulationOFFSIDES
329Post procedural complicationOFFSIDES
330Postoperative ileusOFFSIDES
331PresbyopiaOFFSIDES
332ProctitisOFFSIDES
333Protein total increasedOFFSIDES
334PsoriasisSIDER
335Psychiatric symptomOFFSIDES
336Pulmonary EmbolismSIDER
337Pulmonary Valve StenosisOFFSIDES
338Pulmonary artery stenosisOFFSIDES
339PurpuraSIDER
340Radicular painOFFSIDES
341RageSIDER
342Respiratory FailureOFFSIDES
343Retinal DetachmentSIDER
344Retrosternal painSIDER
345Rheumatoid factor increasedOFFSIDES
346RhinorrheaOFFSIDES
347Right Ventricular DysfunctionOFFSIDES
348Right Ventricular HypertrophyOFFSIDES
349SacroiliitisOFFSIDES
350ScabOFFSIDES
351Schizotypal Personality DisorderOFFSIDES
352ScleritisOFFSIDES
353SclerodermaOFFSIDES
354ScotomaSIDER
355Seizures8905326
11060714
CTD
356ShockSIDER
357Sinus bradycardiaOFFSIDES
SIDER
358SinusitisOFFSIDES
359Skeletal injuryOFFSIDES
360Skin hypertrophySIDER
361Skin lesionOFFSIDES
362Sleep Initiation and Maintenance Disorders10682226
11060714
17557470
CTD
363Slurred speechSIDER
364SnoringSIDER
365Sphincter of Oddi DysfunctionOFFSIDES
366Staphylococcal abscessOFFSIDES
367StiffnessSIDER
368StomatitisSIDER
369StressOFFSIDES
370StuporSIDER
371Subcutaneous AbscessOFFSIDES
372SweatingSIDER
373SwellingSIDER
374SyncopeSIDER
375Synovial fluid analysis abnormalOFFSIDES
376Tardive DyskinesiaOFFSIDES
377TendinitisOFFSIDES
378TenosynovitisSIDER
379TensionSIDER
380ThirstSIDER
381ThrombophlebitisSIDER
382TrismusSIDER
383Ulcerative stomatitisSIDER
384Umbilical herniaOFFSIDES
385Unresponsive to pain stimuliOFFSIDES
386Urethritis noninfectiveSIDER
387UrethritisSIDER
388Urinary RetentionSIDER
389VIIth nerve paralysisSIDER
390Vaginal DischargeSIDER
391Vascular purpuraSIDER
392Ventricular FibrillationOFFSIDES
393Ventricular bigeminySIDER
394Ventricular hypokinesiaOFFSIDES
395Vertebral Artery StenosisOFFSIDES
396Vesiculobullous rashSIDER
397Viral pharyngitisOFFSIDES
398Weight GainOFFSIDES
399Weight decreasedSIDER
400Wound infection pseudomonasOFFSIDES
401effusionOFFSIDES
402muscle injuryOFFSIDES
403nervous system disorderSIDER
404prostatitisOFFSIDES
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