MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Glucagonoma

(UMLS:C0017689)

Definition:: An almost always malignant GLUCAGON-secreting tumor derived from the PANCREATIC ALPHA CELLS. It is characterized by a distinctive migratory ERYTHEMA; WEIGHT LOSS; STOMATITIS; GLOSSITIS; DIABETES MELLITUS; hypoaminoacidemia; and normochromic normocytic ANEMIA.
UMLS ID:: C0017689
MeSH ID:: D005935

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.470.200.025.290.750|C04.588.274.761.500.249|C04.588.322.475.500.249

Classification 2:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.301.761.500.249|C06.689.667.500.249

Classification 3:

Name:

Endocrine System Diseases
MeSH Tree Number(s):: C19.344.421.500.249

Synonym(s)

Glucagonoma

Alpha Cell Tumor

Alpha Cell Tumor of Pancreas

Alpha Cell Tumor of the Pancreas

Alpha cell adenoma

Alpha cell tumor

Alpha-cell adenoma

GLUCAGONOMA

Glucagon-Producing Islet Cell Tumor

10.

Glucagon-Producing Tumor of Islet Cells

11.

Glucagon-Producing Tumor of the Islet Cells

12.

Glucagonoma NOS

13.

Glucagonoma syndrome

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Everolimus	FAERS: 2	US FAERS
2	Ambroxol		OFFSIDES
3	Pramipexole		OFFSIDES
4	voglibose		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Gastrinoma	52.3%
2	Vipoma	45.1%
3	Carcinoma, Pancreatic Ductal	37.2%
4	Peritoneal Neoplasms	24.5%
5	insulinoma	24.2%
6	Parathyroid Neoplasms	21.2%
7	Thyroid Neoplasm	21.2%
8	Thyroid carcinoma	21.2%
9	Gastrointestinal Neoplasms	20.9%
10	Liver neoplasms	20.9%
11	Multiple Endocrine Neoplasia	20.7%
12	Carcinoma, Lobular	17.4%
13	Adrenal Gland Neoplasms	17.3%
14	Esophageal Neoplasms	17%
15	Testicular Neoplasms	15.1%
16	Hepatocellular Adenoma	14.9%
17	Cystadenocarcinoma	14.8%
18	Mucoepidermoid Carcinoma	14.8%
19	Abdominal Neoplasms	14.5%
20	Head and Neck Neoplasms	14.5%
21	Soft Tissue Neoplasms	14.5%
22	Thoracic Neoplasms	14.5%
23	Carcinoma, Ehrlich Tumor	14.2%
24	Carcinoma, Lewis Lung	14.2%
25	Liver Neoplasms, Experimental	14.1%
26	Pancreatic Cyst	13.6%
27	Basal cell carcinoma	13.4%
28	Carcinoma, Papillary	13.4%
29	Squamous cell carcinoma	13.4%
30	Carcinoma, Basal Cell	13.4%
31	Adrenocortical carcinoma	13.4%
32	ovarian neoplasm	13.4%
33	Carcinoma, Ovarian Epithelial	13.1%
34	Bile Duct Neoplasms	13%
35	gallbladder neoplasm	13%
36	Intestinal Neoplasms	13%
37	Stomach Neoplasms	13%
38	Eye Neoplasms	13%
39	Nervous System Neoplasms	13%
40	Bone neoplasms	12.8%
41	Skin Neoplasms	12.8%
42	Hematologic Neoplasms	12.8%
43	Splenic Neoplasms	12.7%
44	Choriocarcinoma	12.6%
45	Thyroid Nodule	12.4%
46	Neoplasms, Neuroepithelial	12.2%
47	Gliomatosis cerebri	12.2%
48	Carcinoid Tumor	12%
49	Hamartoma	11.9%
50	Neoplasms, Hormone-Dependent	11.9%
51	Neoplasms, Multiple Primary	11.9%
52	Paraneoplastic Syndromes	11.9%
53	Precancerous Conditions	11.9%
54	Neoplasms, Second Primary	11.9%
55	Pituitary Adenoma	11.9%
56	Pituitary Neoplasms	11.9%
57	Prolactinoma	11.7%
58	Growth Hormone-Secreting Pituitary Adenoma	11.7%
59	Multiple Endocrine Neoplasia Type 1	11.7%
60	Acanthoma	11.7%
61	Adenoid Cystic Carcinoma	11.5%
62	Adenocarcinoma, Clear Cell	11.5%
63	Cholangiocarcinoma	11.5%
64	Digestive System Neoplasms	11.2%
65	Paraneoplastic Encephalomyelitis	11.1%
66	Zollinger-Ellison syndrome	11.1%
67	Mammary Neoplasms, Experimental	11%
68	Pancreatic Fistula	10.9%
69	Cyst	10.5%
70	Neoplastic Processes	10.5%
71	Neoplastic Syndromes, Hereditary	10.5%
72	Pregnancy Complications, Neoplastic	10.5%
73	Neoplasms, Experimental	10.4%
74	Adenomatous Polyposis Coli	10.2%
75	leukemia	10.1%
76	Neoplasms, Germ Cell and Embryonal	10.1%
77	Germ Cell Cancer	10.1%
78	Carcinoma in Situ	9.9%
79	Carcinoma, Transitional Cell	9.9%
80	Carcinoma, Large Cell	9.9%
81	Carcinoma, Small Cell	9.9%
82	Meningioma	9.8%
83	Choledochal Cyst	9.6%
84	Adenoma	9.5%
85	Neuroectodermal Tumors	9.5%
86	Cystadenoma	9.4%
87	Mesothelioma	9.4%
88	Neoplasms, Radiation-Induced	9.3%
89	Colorectal Neoplasms	9.3%
90	Pancreatic Insufficiency	9.3%
91	Pancreatitis	9.3%
92	granulosa cell tumor	9.1%
93	Trophoblastic Neoplasms	9.1%
94	Leukemia, Experimental	9%
95	Tracheal Neoplasms	9%
96	Cecal Neoplasms	9%
97	Duodenal Neoplasms	9%
98	Pancreatic Neoplasm	8.9%
99	Gastrointestinal Stromal Tumors	8.9%
100	Histiocytic Disorders, Malignant	8.9%
101	Tuberous Sclerosis	8.8%
102	Carcinoma 256, Walker	8.7%
103	Carcinoma, Endometrioid	8.6%
104	Renal Cell Carcinoma	8.5%
105	Papillary Renal Cell Carcinoma	8.5%
106	Biliary Tract Diseases	8.5%
107	Gastrointestinal Diseases	8.5%
108	Liver diseases	8.5%
109	Leukemia, Radiation-Induced	8.2%
110	Bowen's Disease	8.2%
111	Malignant Carcinoid Syndrome	8.1%
112	Dermoid Cyst	8.1%
113	Retroperitoneal Neoplasms	7.9%
114	Basal Cell Nevus Syndrome	7.9%
115	Thymoma	7.9%
116	Lymphoma	7.9%
117	Barrett Esophagus	7.8%
118	Pancreatic Pseudocyst	7.8%
119	Klatskin Tumor	7.7%
120	Melanoma, Experimental	7.6%
121	Retinoblastoma	7.6%
122	Composite Lymphoma	7.6%
123	Carcinosarcoma	7.4%
124	Hemangiosarcoma	7.4%
125	lymphangiosarcoma	7.4%
126	Endocrine Gland Neoplasms	7.4%
127	Nephroblastoma	7.3%
128	melanoma	7.2%
129	Sarcoma, Experimental	7.2%
130	Adenoma, Acidophil	7.2%
131	Ganglioneuroma	7.2%
132	Glioma	7.2%
133	Malignant Glioma	7.2%
134	Mouth Neoplasms	7%
135	Central Nervous System Neoplasms	7%
136	Vascular Neoplasms	7%
137	Thymus Neoplasms	7%
138	Medulloblastoma	7%
139	Genital Neoplasms, Female	7%
140	Breast Neoplasms, Male	6.9%
141	Triple Negative Breast Neoplasms	6.9%
142	Leydig Cell Tumor	6.7%
143	Cystic Fibrosis	6.7%
144	Appendiceal Neoplasms	6.7%
145	Colonic Neoplasms	6.7%
146	Rectal Neoplasms	6.7%
147	Leukemia, Plasma Cell	6.6%
148	Nasopharyngeal carcinoma	6.6%
149	Congenital Hyperinsulinism	6.5%
150	Genital Neoplasms, Male	6.3%
151	Uveal Neoplasms	6.3%
152	Urologic Neoplasms	6.3%
153	Sebaceous Gland Neoplasms	6.2%
154	Spinal Neoplasms	6.2%
155	Bone Marrow Neoplasms	6.2%
156	Erythroplasia	6.1%
157	Follicular cyst	6.1%
158	Mucocele	6.1%
159	Pilonidal Cyst	6.1%
160	Thyroglossal Cyst	6.1%
161	Synovial Cyst	6.1%
162	Aberrant Crypt Foci	6.1%
163	Cervical Intraepithelial Neoplasia	6%
164	Nelson Syndrome	6%
165	Adenofibroma	5.9%
166	Fibroadenoma	5.9%
167	Corpus Luteum Cyst	5.9%
168	Ovarian Cysts	5.9%
169	Anus Neoplasms	5.9%
170	Sigmoid Neoplasms	5.9%
171	Mesenteric vascular insufficiency	5.8%
172	Esophageal Atresia	5.8%
173	Intestinal Atresia	5.8%
174	Mesenteric Vascular Occlusion	5.8%
175	Intestinal Fistula	5.8%
176	Enterocutaneous Fistula	5.8%
177	Leukoplakia, Oral	5.7%
178	Carcinoid Heart Disease	5.7%
179	Paraneoplastic Cerebellar Degeneration	5.6%
180	Lymphomatoid Granulomatosis	5.6%
181	Leukemia L1210	5.6%
182	Leukemia P388	5.6%
183	Acoustic Neuroma	5.6%
184	Peutz-Jeghers Syndrome	5.6%
185	Pancreatitis, Chronic	5.5%
186	Leukoplakia	5.4%
187	Lymphocele	5.4%
188	Chondrosarcoma	5.4%
189	Craniopharyngioma	5.4%
190	leiomyosarcoma	5.4%
191	liposarcoma	5.4%
192	synovial sarcoma	5.4%
193	Neuroectodermal Tumor, Melanotic	5.4%
194	Angiomyolipoma	5.4%
195	Clear Cell Sarcoma of Soft Tissue	5.4%
196	Alveolar Soft Part Sarcoma	5.4%
197	Neuroendocrine Tumors	5.4%
198	Sarcoma, Myeloid	5.4%
199	Ameloblastoma	5.4%
200	Angiokeratoma	5.4%
201	Chordoma	5.4%
202	Hemangioma	5.4%
203	hemangiopericytoma	5.4%
204	Lymphangioma	5.4%
205	Mesenchymoma	5.4%
206	Nevus	5.4%
207	Teratoma	5.4%
208	Hepatoblastoma	5.4%
209	Mixed Tumor, Mullerian	5.4%
210	Germinoma	5.4%
211	Teratocarcinoma	5.4%
212	Angiofibroma	5.4%
213	Sarcoma	5.4%
214	Breast Cyst	5.4%
215	Actinic keratosis	5.4%
216	Mediastinal Cyst	5.4%
217	Neoplasm Invasiveness	5.4%
218	Neoplasm Metastasis	5.4%
219	Neoplasm Recurrence, Local	5.4%
220	Parovarian Cyst	5.4%
221	Pericardial Cyst	5.4%
222	Thymic Cyst	5.4%
223	Carcinogenesis	5.4%
224	Myxoid cyst	5.4%
225	Metastasis	5.4%
226	Biliary cirrhosis	5.4%
227	Papilloma	5.4%
228	Pseudomyxoma Peritonei	5.4%
229	Papillomatosis	5.4%
230	Adenomatosis, Pulmonary	5.4%
231	Adenomatous Polyps	5.4%
232	Nose Neoplasms	5.2%
233	Limbic Encephalitis	5.1%
234	Endometrial Stromal Sarcoma	5.1%
235	Optic Nerve Glioma	5%
236	Mesoblastic Nephroma	4.9%
237	Proctocolitis	4.9%
238	Dysentery	4.8%
239	Enteritis	4.8%
240	Enterocolitis	4.8%
241	Esophageal and Gastric Varices	4.8%
242	Esophagitis	4.8%
243	Gastritis	4.8%
244	Inflammatory Bowel Diseases	4.8%
245	Cholecystolithiasis	4.8%
246	Pancreatitis, Alcoholic	4.8%
247	Lambert-Eaton Myasthenic Syndrome	4.8%
248	Plasmacytoma	4.7%
249	Malignant histiocytosis	4.7%
250	Histiocytic sarcoma	4.7%
251	Astrocytoma	4.7%
252	Ependymoma	4.7%
253	oligodendroglioma	4.7%
254	Ganglioglioma	4.7%
255	gliosarcoma	4.7%
256	Anaplastic astrocytoma	4.7%
257	Anaplastic Oligodendroglioma	4.7%
258	Bile Duct Diseases	4.6%
259	Cholelithiasis	4.6%
260	Chylous Ascites	4.6%
261	Esophageal Diseases	4.6%
262	Fatty Liver	4.6%
263	Gastroenteritis	4.6%
264	Hepatitis	4.6%
265	Portal Hypertension	4.6%
266	Intestinal Diseases	4.6%
267	Liver Cirrhosis	4.6%
268	Pneumoperitoneum	4.6%
269	Stomach Diseases	4.6%
270	Focal Nodular Hyperplasia	4.6%
271	Hepatic Insufficiency	4.6%
272	Steatohepatitis	4.6%
273	Sarcoma 180	4.6%
274	Palatal Neoplasms	4.6%
275	Neurilemmoma	4.5%
276	Hutchinson's Melanotic Freckle	4.5%
277	Melanoma, Amelanotic	4.5%
278	Rectal Fistula	4.5%
279	Anal Fistula	4.5%
280	Opsoclonus-Myoclonus Syndrome	4.4%
281	Fibrosarcoma	4.4%
282	Osteosarcoma	4.4%
283	Lymphangioleiomyomatosis	4.3%
284	Fatty Liver, Alcoholic	4.3%
285	Hepatitis, Alcoholic	4.3%
286	Liver Cirrhosis, Alcoholic	4.3%
287	Duodenitis	4.3%
288	Ileitis	4.3%
289	Erosive Duodenitis	4.3%
290	Adrenal Gland Diseases	4.3%
291	Gonadal Disorders	4.3%
292	Pancreatic Diseases	4.3%
293	Parathyroid Diseases	4.3%
294	Thyroid Diseases	4.3%
295	Hodgkin Disease	4.2%
296	Lymphoma, Non-Hodgkin	4.2%
297	Neoplasms, Glandular and Epithelial	4.2%
298	Liver Diseases, Parasitic	4.2%
299	Meningeal Neoplasms	4.1%
300	Hepatic Veno-Occlusive Disease	4.1%
301	Peliosis Hepatis	4.1%
302	Hepatopulmonary Syndrome	4.1%
303	Anus, Imperforate	4.1%
304	Gastrointestinal Hemorrhage	4.1%
305	Hemoperitoneum	4.1%
306	Hepatomegaly	4.1%
307	Mesenteric Panniculitis	4.1%
308	Panniculitis, Peritoneal	4.1%
309	Peritonitis	4.1%
310	Peritoneal Fibrosis	4.1%
311	Encapsulating Peritoneal Sclerosis	4.1%
312	Anorectal Malformations	4.1%
313	Myelitis, Transverse	4.1%
314	Biliary Fistula	4.1%
315	Gastric Fistula	4.1%
316	Hepatic Vein Thrombosis	4%
317	Liver Abscess	4%
318	Budd-Chiari Syndrome	4%
319	Tuberculosis, Gastrointestinal	4%
320	Colitis	4%
321	Duodenogastric Reflux	4%
322	Peptic Ulcer	4%
323	Proctitis	4%
324	Choledocholithiasis	4%
325	Malignant Fibrous Histiocytoma	3.9%
326	Nesidioblastosis	3.9%
327	Primary amyloidosis	3.8%
328	Bone Diseases, Endocrine	3.8%
329	Ear Neoplasms	3.7%
330	Eyelid Neoplasms	3.7%
331	Lung Neoplasms	3.7%
332	Pleural Neoplasms	3.7%
333	Denys-Drash Syndrome	3.7%
334	Diabetes Mellitus	3.7%
335	Pituitary Diseases	3.7%
336	Chemical and Drug Induced Liver Injury	3.7%
337	Brain Neoplasms	3.7%
338	Salivary Gland Neoplasms	3.7%
339	Spinal Cord Neoplasms	3.7%
340	Tongue Neoplasms	3.7%
341	Uterine Neoplasms	3.7%
342	Vaginal Neoplasms	3.7%
343	Vulvar Neoplasms	3.7%
344	Uterine Cancer	3.7%
345	Fallopian Tube Neoplasms	3.6%
346	Hepatorenal Syndrome	3.6%
347	Appendicitis	3.6%
348	Liver Abscess, Amebic	3.6%
349	Glucagonoma	3.5%
350	Glioblastoma	3.4%
351	Neuroblastoma	3.4%
352	Glioblastoma Multiforme	3.4%
353	Paraganglioma	3.4%
354	Rhabdomyosarcoma	3.4%
355	Giant Cell Tumor of Bone	3.4%
356	Pharyngeal Neoplasms	3.4%
357	Central Nervous System Cysts	3.3%
358	Dwarfism	3.3%
359	Neurofibrosarcoma	3.3%
360	Penile Neoplasms	3.3%
361	Prostatic Neoplasms	3.3%
362	Polycystic Ovary Syndrome	3.3%
363	Polycythemia Vera	3.3%
364	Porphyrias, Hepatic	3.3%
365	Crohn Disease	3.2%
366	Duodenal Obstruction	3.2%
367	Enterocolitis, Neutropenic	3.2%
368	Necrotizing Enterocolitis	3.2%
369	Pouchitis	3.2%
370	Waldenstrom Macroglobulinemia	3.2%
371	Multiple Myeloma	3.2%
372	Xeroderma Pigmentosum	3.1%
373	Laryngeal neoplasm	3.1%
374	Phyllodes Tumor	3.1%
375	Dysgerminoma	3.1%
376	Hemangioendothelioma	3.1%
377	Lipoma	3.1%
378	Myoma	3.1%
379	Myxoma	3.1%
380	Neuroma	3.1%
381	Seminoma	3.1%
382	Angiolipoma	3.1%
383	Myelolipoma	3.1%
384	Neoplasms, Bone Tissue	3.1%
385	Neoplasms, Fibrous Tissue	3.1%
386	Smooth Muscle Tumor	3.1%
387	Desmoplastic Small Round Cell Tumor	3.1%
388	Chondroma	3.1%
389	Enchondroma	3.1%
390	Hydatidiform Mole	3%
391	Bladder Neoplasm	3%
392	Kidney Neoplasm	3%
393	Ureteral Neoplasms	3%
394	Urethral Neoplasms	3%
395	Lymphatic Metastasis	2.9%
396	Neoplasms, Unknown Primary	2.9%
397	Leukemic Infiltration	2.9%
398	Neoplasm Micrometastasis	2.9%
399	Dermatofibrosarcoma	2.9%
400	Dermatofibrosarcoma Protuberans	2.9%
401	Enterocolitis, Pseudomembranous	2.8%
402	pseudomembranous colitis	2.8%
403	Dysentery, Bacillary	2.8%
404	Ganglioneuroblastoma	2.8%
405	Duodenal Ulcer	2.8%
406	Peptic Ulcer Perforation	2.8%
407	Gastric ulcer	2.8%
408	Cecal Diseases	2.8%
409	Cholangitis	2.8%
410	Cholecystitis	2.8%
411	Cholestasis	2.8%
412	Colonic Diseases	2.8%
413	Common Bile Duct Diseases	2.8%
414	Esophageal Stenosis	2.8%
415	Hepatitis, Chronic	2.8%
416	Ileal Diseases	2.8%
417	Intestinal Obstruction	2.8%
418	Intestinal Perforation	2.8%
419	Jejunal Diseases	2.8%
420	Pneumatosis Cystoides Intestinalis	2.8%
421	Rectal Diseases	2.8%
422	Gastric Dilatation	2.8%
423	Liver Failure	2.8%
424	Gastric outlet obstruction	2.8%
425	Cronkhite-Canada Syndrome	2.8%
426	Non-alcoholic Fatty Liver Disease	2.8%
427	Chronic active hepatitis	2.8%
428	Intestinal Polyposis	2.8%
429	Leukemia, Myelomonocytic, Chronic	2.7%
430	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	2.7%
431	Meningeal Carcinomatosis	2.7%
432	Colitis, Ischemic	2.5%
433	Esophageal Perforation	2.5%
434	Hepatitis, Animal	2.5%
435	Hepatitis, Viral, Human	2.5%
436	Intestinal Diseases, Parasitic	2.5%
437	Deglutition Disorders	2.4%
438	Mastocytosis	2.4%
439	Sturge-Weber Syndrome	2.4%
440	Bronchial Neoplasms	2.4%
441	Achlorhydria	2.4%
442	Liver Cirrhosis, Experimental	2.4%
443	Gastric Antral Vascular Ectasia	2.4%
444	Multiple Pulmonary Nodules	2.4%
445	Hemangioma, Cavernous	2.4%
446	Peptic Ulcer Hemorrhage	2.4%
447	Gastroparesis	2.4%
448	Leukemia, T-Cell	2.4%
449	Leukemia, B-Cell	2.4%
450	neurofibroma	2.4%
451	Supratentorial Neoplasms	2.4%
452	Lymphoma, Follicular	2.4%
453	T-Cell Lymphoma	2.4%
454	Mantle cell lymphoma	2.4%
455	Endometrial Neoplasms	2.4%
456	Pheochromocytoma	2.4%
457	Alveolar rhabdomyosarcoma	2.4%
458	Congenital Hypothyroidism	2.4%
459	Adrenal Cortex Diseases	2.3%
460	Euthyroid Sick Syndromes	2.3%
461	Goiter	2.3%
462	Hyperparathyroidism	2.3%
463	Hyperthyroidism	2.3%
464	Hyperthyroxinemia	2.3%
465	Hypogonadism	2.3%
466	Hypoparathyroidism	2.3%
467	Hypothyroidism	2.3%
468	Delayed Puberty	2.3%
469	Precocious Puberty	2.3%
470	Thyroiditis	2.3%
471	Hypogonadotropic hypogonadism	2.3%
472	Testotoxicosis	2.3%
473	Secondary hypothyroidism	2.3%
474	Primary Hyperthyroidism	2.3%
475	Primary Hypothyroidism	2.3%
476	Carcinoma	2.3%
477	Epithelioma	2.3%
478	Hepatitis B, Chronic	2.2%
479	Hepatitis C, Chronic	2.2%
480	Colonic Pseudo-Obstruction	2.2%
481	Hypopharyngeal Neoplasms	2.2%
482	Pleural Effusion, Malignant	2.2%
483	Hypopharyngeal Cancer	2.2%
484	Fascioliasis	2.2%
485	Echinococcosis, Hepatic	2.2%
486	Melena	2.2%
487	Parotid Neoplasms	2.2%
488	Prostatic Neoplasms, Castration-Resistant	2.2%
489	Chemical and Drug Induced Liver Injury, Chronic	2.2%
490	Reye Syndrome	2.2%
491	Hematemesis	2.1%
492	Testicular Diseases	2.1%
493	Zellweger Syndrome	2%
494	Ovarian Diseases	2%
495	Empty Sella Syndrome	2%
496	Hyperpituitarism	2%
497	Hypopituitarism	2%
498	Hypophysitis	2%
499	Graves Disease	2%
500	fibroma	1.9%
501	Fibromatosis	1.9%
502	Osteoblastoma	1.9%
503	Osteoma	1.9%
504	Rhabdomyoma	1.9%
505	Chondromatosis	1.9%
506	Hemangioblastoma	1.9%
507	Lymphoma, Extranodal NK-T-Cell	1.9%
508	Variegate Porphyria	1.9%
509	Acute intermittent porphyria	1.9%
510	Porphyria Cutanea Tarda	1.9%
511	Hepatolenticular Degeneration	1.9%
512	Cholestasis, Extrahepatic	1.8%
513	Biliary Dyskinesia	1.8%
514	Cholangitis, Sclerosing	1.8%
515	Colonic Diseases, Functional	1.8%
516	Esophageal motility disorders	1.8%
517	Fecal Incontinence	1.8%
518	Fecal Impaction	1.8%
519	Intussusception	1.8%
520	Mallory-Weiss Syndrome	1.8%
521	Megacolon	1.8%
522	Pyloric Stenosis	1.8%
523	Liver Failure, Acute	1.8%
524	Acalculous Cholecystitis	1.8%
525	End Stage Liver Disease	1.8%
526	Ileus	1.8%
527	Meconium ileus	1.8%
528	Nasopharyngeal Neoplasms	1.8%
529	Gestational Diabetes	1.8%
530	Latent Autoimmune Diabetes in Adults	1.8%
531	Diabetes Insipidus	1.8%
532	Diabetes Mellitus, Experimental	1.8%
533	Brain Stem Neoplasms	1.8%
534	Mastocytoma	1.7%
535	Mastocytosis, Systemic	1.7%
536	Leukemia, Myeloid, Chronic-Phase	1.7%
537	Paranasal Sinus Neoplasms	1.7%
538	Hermaphroditism	1.6%
539	Disorders of Sex Development	1.6%
540	Hemorrhoids	1.6%
541	Autoimmune hepatitis	1.6%
542	Pituitary Apoplexy	1.6%
543	Afferent Loop Syndrome	1.6%
544	Celiac Disease	1.6%
545	Short Bowel Syndrome	1.6%
546	Sprue, Tropical	1.6%
547	Steatorrhea	1.6%
548	Rectocele	1.6%
549	Sprue	1.6%
550	Diverticulitis	1.6%
551	Dumping Syndrome	1.6%
552	Rectal Prolapse	1.6%
553	Tonsillar Neoplasms	1.6%
554	Cerebellar Neoplasms	1.6%
555	Cell Transformation, Viral	1.5%
556	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1.5%
557	Leukemia, Large Granular Lymphocytic	1.5%
558	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1.5%
559	Lymphoma, T-Cell, Cutaneous	1.5%
560	Lymphoma, AIDS-Related	1.5%
561	Enteropathy-Associated T-Cell Lymphoma	1.5%
562	Primary Effusion Lymphoma	1.5%
563	Hepatitis, Viral, Animal	1.5%
564	Choroid Plexus Papilloma	1.5%
565	Giardiasis	1.5%
566	Hepatitis E	1.5%
567	Hepatitis B	1.4%
568	Hepatitis C	1.4%
569	Diverticulum	1.4%
570	Hepatitis A	1.4%
571	Diverticulosis	1.4%
572	Hepatic Encephalopathy	1.4%
573	Cushing Syndrome	1.4%
574	Hyperaldosteronism	1.4%
575	Hyperparathyroidism, Secondary	1.4%
576	Hypoaldosteronism	1.4%
577	Thyrotoxicosis	1.4%
578	Hyperparathyroidism, Primary	1.4%
579	Thyroid Hormone Resistance Syndrome	1.4%
580	Adenocarcinoma	1.4%
581	Massive Hepatic Necrosis	1.4%
582	Esophageal Achalasia	1.4%
583	Anal Fissure	1.4%
584	Intestinal Pseudo-Obstruction	1.4%
585	Irritable Bowel Syndrome	1.4%
586	Superior Mesenteric Artery Syndrome	1.4%
587	Emphysematous Cholecystitis	1.4%
588	Neurogenic Bowel	1.4%
589	Sphincter of Oddi Dysfunction	1.4%
590	Anal Ulcer	1.4%
591	Fibromatosis, Aggressive	1.4%
592	Fibromatosis, Abdominal	1.4%
593	Kallmann Syndrome	1.3%
594	Lactose Intolerance	1.3%
595	Diabetic Foot	1.3%
596	Burkitt Lymphoma	1.2%
597	Maxillary Sinus Neoplasms	1.2%
598	Klinefelter Syndrome	1.2%
599	Addison Disease	1.2%
600	Diabetic Angiopathies	1.2%
601	Autoimmune thyroiditis	1.2%
602	Primary Adrenal Insufficiency	1.2%
603	Diabetic Neuropathies	1.2%
604	Myxedema	1.2%
605	Orchitis	1.2%
606	Diabetic Amyotrophy	1.2%
607	Diabetic Autonomic Neuropathy	1.2%
608	Diabetic Cardiomyopathies	1.2%
609	Pruritus Ani	1.2%
610	Ovarian Hyperstimulation Syndrome	1.2%
611	Hyperprolactinemia	1.2%
612	Cryptosporidiosis	1.1%
613	Dupuytren Contracture	1.1%
614	Gigantism	1.1%
615	Diabetic Nephropathy	1.1%
616	Acromegaly	1.1%
617	Anovulation	1.1%
618	Diabetic Ketoacidosis	1.1%
619	Urticaria Pigmentosa	1.1%
620	Oophoritis	1.1%
621	Mycosis Fungoides	1.1%
622	Lymphomatoid Papulosis	1.1%
623	Plasmablastic lymphoma	1.1%
624	Laryngopharyngeal Reflux	1%
625	Cryptorchidism	1%
626	Gonadal Dysgenesis	1%
627	Adrenogenital Syndrome	1%
628	Ovotesticular Disorders of Sex Development	1%
629	Hyperglycemic Hyperosmolar Nonketotic Coma	0.9%
630	Hashimoto Disease	0.9%
631	Hyperandrogenism	0.9%
632	Sezary Syndrome	0.9%
633	Rift Valley Fever	0.8%
634	CREST Syndrome	0.8%
635	Diabetic Retinopathy	0.7%
636	Turner Syndrome	0.7%
637	Waterhouse-Friderichsen Syndrome	0.6%
638	Radicular Cyst	0.6%
639	Renal Osteodystrophy	0.5%
640	Renal rickets	0.5%
641	Adrenoleukodystrophy	0.4%

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