MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypocalcemia

(UMLS:C0020598)

Definition:: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
UMLS ID:: C0020598
MeSH ID:: D006996

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.174.509|C18.452.950.509

Synonym(s)

Hypocalcemia

Calcium deficiency disease

HYPOCALCAEMIA

HYPOCALCEMIA

Hypocalcaemia

Hypocalcaemia syndrome

Associated Drug(s)

	Name	Reference(s)	Data Source
1	24,25-Dihydroxyvitamin D 3	6760236	CTD
2	Alendronate	12730757	CTD
3	Amifostine	19813275	CTD
4	Amikacin	856439 19884751	CTD
5	Amisulpride	15953230	CTD
6	Aspirin	4004906	CTD
7	Cadmium Compounds	15316864	CTD
8	Calcitriol	80633 6760236	CTD
9	Calcium Carbonate	12585729	CTD
10	Calcium Compounds	8490193 9785681	CTD
11	Capecitabine	19584382	CTD
12	Carbamazepine	16136018	CTD
13	Cesium	18797846	CTD
14	Colistin	646445	CTD
15	Cyclophosphamide	4833837 10637075	CTD
16	Dacarbazine	7916039	CTD
17	Didanosine	1659189	CTD
18	Docetaxel	17846704	CTD
19	Edetic Acid	3103339 9787496	CTD
20	Egtazic Acid	3144597	CTD
21	Erythromycin Ethylsuccinate	18653914	CTD
22	Estramustine	17846704	CTD
23	Foscarnet	8384030	CTD
24	Fusidic Acid	11823554	CTD
25	Gentamicins	View details 727798 856439 2331318 7354245	CTD
26	Glutethimide	1273917	CTD
27	Imatinib Mesylate	17040091	CTD
28	Irinotecan	19584382	CTD
29	Isoproterenol	21076021	CTD
30	Magnesium Sulfate	View details 3028586 3082455 6069279 7731416 12190013 12357887	CTD
31	Methimazole	1657745	CTD
32	Methylprednisolone	7618796	CTD
33	Neomycin	646445	CTD
34	Norinyl	820624	CTD
35	Omeprazole	18221401	CTD
36	Pamidronate	16006300	CTD
37	Pentamidine	2393042	CTD
38	Phenobarbital	849004	CTD
39	Phenytoin	849004	CTD
40	Polymyxin B	646445	CTD
41	Prednisone	4833837	CTD
42	Promethazine	10548178	CTD
43	Pyrazinamide	4340029	CTD
44	Ritodrine	3883263	CTD
45	Sisomicin	856439	CTD
46	Sodium Citrate	17111419	CTD
47	Tobramycin	856439	CTD
48	Vincristine	4833837	CTD
49	Viomycin	4340029	CTD
50	Vitamin D	80633	CTD
51	Zoledronic Acid	View details 12669777 17491196 17846704 18683218	CTD
52	alfacalcidol	11701698	CTD
53	calcium lactate	1657745	CTD
54	methylmercuric chloride	15316864	CTD
55	reviparin	16678734	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hypercalcemia	66.7%
2	Milk-Alkali Syndrome	66.7%
3	Calcinosis	44.4%
4	Hyperkalemia	44.4%
5	Hypernatremia	44.4%
6	Hypokalemia	44.4%
7	Hyponatremia	44.4%
8	Wasting Syndrome	41.4%
9	Acid-Base Imbalance	40.9%
10	Iron Metabolism Disorders	40.9%
11	Phosphorus Metabolism Disorders	40.9%
12	Lipid Metabolism Disorders	40.9%
13	Mitochondrial Diseases	40.9%
14	Glucose Metabolism Disorders	40.9%
15	Pseudohypoparathyroidism	38.7%
16	Rickets	37.7%
17	Dehydration	33.9%
18	Water Intoxication	33.9%
19	Calciphylaxis	33%
20	Vascular calcification	33%
21	Lipodystrophy	32%
22	Osteopenia	31%
23	Brain Diseases, Metabolic	30.5%
24	Osteomalacia	28.3%
25	Leigh Disease	27%
26	Acidosis	26.7%
27	Alkalosis	26.7%
28	Amyloidosis	26.7%
29	Hyperglycemia	26.7%
30	Hyperinsulinism	26.7%
31	Hypoglycemia	26.7%
32	Xanthomatosis	26.7%
33	Hypophosphatemia	26.7%
34	Metabolic acidosis	26.7%
35	Dyslipidemias	26.7%
36	Iron Overload	26.7%
37	Xanthoma	26.7%
38	Brain Diseases, Metabolic, Inborn	26.5%
39	Hyperhomocysteinemia	25.3%
40	Carbamoyl-Phosphate Synthase I Deficiency Disease	24.7%
41	Hyperlipoproteinemia Type IV	24.3%
42	Hyperlipoproteinemia Type V	24.3%
43	Nutrition Disorders	23.8%
44	Familial Hypophosphatemic Rickets	23.7%
45	Hypolipoproteinemias	23.5%
46	Lactose Intolerance	23%
47	Smith-Lemli-Opitz Syndrome	22%
48	Galactosemias	21.9%
49	Urea Cycle Disorders, Inborn	21.9%
50	Tyrosinemias	21.9%
51	Diabetic Ketoacidosis	21.6%
52	Hyperlipidemia, Familial Combined	21.5%
53	Diabetes Mellitus	21.1%
54	Hyperlipoproteinemia Type III	20.5%
55	Calcium Metabolism Disorders	20.5%
56	Water-Electrolyte Imbalance	20.5%
57	Lipomatosis	20.3%
58	Werner Syndrome	20.3%
59	Congenital Hyperinsulinism	20.2%
60	Achlorhydria	20%
61	Amino Acid Metabolism, Inborn Errors	20%
62	Bloom Syndrome	20%
63	Carbohydrate Metabolism, Inborn Errors	20%
64	Hypocalcemia	20%
65	Metal Metabolism, Inborn Errors	20%
66	Osteoporosis	20%
67	Progeria	20%
68	Lysosomal Storage Diseases	20%
69	Bone Demineralization, Pathologic	20%
70	Cytochrome-c Oxidase Deficiency	20%
71	Peroxisomal Disorders	20%
72	Post-Traumatic Osteoporosis	20%
73	Gaucher Disease	20%
74	Celiac Disease	19.8%
75	Sprue, Tropical	19.8%
76	Steatorrhea	19.8%
77	Sprue	19.8%
78	Acidosis, Lactic	19.8%
79	Hemosiderosis	19.8%
80	Ketosis	19.8%
81	Ketonuria	19.8%
82	Ketoacidosis	19.8%
83	Ketonemia	19.8%
84	Nephrocalcinosis	19.7%
85	Mitochondrial Encephalomyopathies	19.7%
86	Hyperphosphaturia	19.5%
87	Hypoalphalipoproteinemias	19.4%
88	Glycogen storage disease type II	19.2%
89	Renal Osteodystrophy	18.9%
90	Renal rickets	18.9%
91	Homocystinuria	18.5%
92	Tay-Sachs Disease	17.9%
93	Amyloid Neuropathies, Familial	17.4%
94	Niemann-Pick Disease, Type C	17%
95	Renal tubular acidosis	16.7%
96	Hypercholesterolemia	16.4%
97	Hyperlipoproteinemias	16.4%
98	Hypertriglyceridemia	16.4%
99	Nesidioblastosis	16.4%
100	Mitochondrial Myopathies	16.2%
101	Myelinolysis, Central Pontine	16.1%
102	Glycosuria	15.9%
103	Reye Syndrome	15.9%
104	Hepatic Encephalopathy	15.8%
105	Fabry Disease	15.7%
106	Neuronal Ceroid-Lipofuscinoses	15.4%
107	Adrenoleukodystrophy	15.1%
108	HIV Wasting Syndrome	15.1%
109	MELAS Syndrome	15%
110	Acidosis, Respiratory	14.9%
111	Adiposis Dolorosa	14.9%
112	Alkalosis, Respiratory	14.9%
113	Zellweger Syndrome	14.8%
114	Alkaptonuria	14.8%
115	Glycogen Storage Disease	14.8%
116	Hypophosphatasia	14.8%
117	Insulin Resistance	14.8%
118	Osteoporosis, Postmenopausal	14.8%
119	Propionic acidemia	14.8%
120	Dihydropyrimidine Dehydrogenase Deficiency	14.8%
121	Cystinosis	14.8%
122	HIV-Associated Lipodystrophy Syndrome	14.7%
123	Menkes Kinky Hair Syndrome	14.6%
124	Mucopolysaccharidosis III	13.8%
125	Hepatolenticular Degeneration	13.7%
126	Child Nutrition Disorders	13.6%
127	Hypervitaminosis A	13.6%
128	Infant Nutrition Disorders	13.6%
129	Malnutrition	13.6%
130	Porphyrias, Hepatic	13.5%
131	Refsum Disease	13.5%
132	Wernicke Encephalopathy	13.3%
133	Necrobiosis Lipoidica Diabeticorum	13.3%
134	Fanconi Anemia	13.1%
135	Glycosuria, Renal	12.9%
136	Gestational Diabetes	12.2%
137	Latent Autoimmune Diabetes in Adults	12.2%
138	CREST Syndrome	12.2%
139	Glycogen Storage Disease Type I	12.2%
140	Glycogen Storage Disease Type V	12.2%
141	Diabetes Mellitus, Experimental	12.1%
142	Cerebral Amyloid Angiopathy	11.7%
143	Friedreich Ataxia	11.2%
144	Kearns-Sayre syndrome	10.5%
145	Kernicterus	10%
146	Familial Periodic Paralysis	10%
147	Cockayne Syndrome	10%
148	Primary amyloidosis	9.9%
149	Variegate Porphyria	9.8%
150	Acute intermittent porphyria	9.8%
151	Porphyria Cutanea Tarda	9.8%
152	Sjogren-Larsson Syndrome	9.8%
153	Renal Aminoacidurias	9.8%
154	Fanconi Syndrome	9.8%
155	Pseudohypoaldosteronism	9.8%
156	Liddle Syndrome	9.8%
157	Canavan Disease	9.7%
158	Alexander Disease	9.7%
159	Mucopolysaccharidosis II	9.7%
160	Ataxia Telangiectasia	9%
161	Deficiency Diseases	8.9%
162	Starvation	8.9%
163	Refeeding Syndrome	8.9%
164	Optic Atrophy, Hereditary, Leber	8.7%
165	Gout	8.6%
166	Amyotrophic Lateral Sclerosis	8.5%
167	Antley-Bixler Syndrome Phenotype	8.4%
168	Hypokalemic periodic paralysis	8.2%
169	Frontotemporal dementia	8.1%
170	Cystinuria	8.1%
171	Xeroderma Pigmentosum	8.1%
172	Arthritis, Gouty	7%
173	Albinism	6.6%
174	Kwashiorkor	6.6%
175	Magnesium Deficiency	6.6%
176	Potassium Deficiency	6.6%
177	Protein Deficiency	6.6%
178	Avitaminosis	6.6%
179	Tetany	5.9%
180	Ascorbic Acid Deficiency	5.5%
181	Vitamin A Deficiency	5.5%
182	Vitamin D Deficiency	5.5%
183	Vitamin E Deficiency	5.5%
184	Marasmus	5.5%
185	Ichthyosis, X-Linked	5.4%
186	Folic Acid Deficiency	4.9%
187	Pellagra	4.9%
188	Thiamine Deficiency	4.9%
189	Vitamin B 12 Deficiency	4.9%
190	Vitamin B 6 Deficiency	4.9%
191	Pyridoxine Deficiency	4.9%
192	Beriberi	4.6%
193	Obesity	4.3%
194	Obesity, Abdominal	3.9%
195	Anemia, Pernicious	3.4%
196	Vitamin K Deficiency	3.3%
197	Pediatric Obesity	3.2%
198	Scurvy	2.9%
199	Prader-Willi Syndrome	2.8%
200	Subacute Combined Degeneration	2%

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