MetaADEDB 2.0 @ LMMD
Ibandronic Acid
(MPBVHIBUJCELCL-UHFFFAOYSA-N)
Structure
SMILES
CCCCCN(CCC(P(=O)(O)O)(P(=O)(O)O)O)C
Type(s)
Approved; Investigational
ATC code(s)
M05BA06; M05BB09
Molecular Formula:
C9H23NO7P2
Molecular Weight:
319.229
Log P:
0.5000
Hydrogen Bond Acceptor:
8
Hydrogen Bond Donor:
5
TPSA:
158.15
CAS Number(s):
114084-78-5; 1130899-41-0
Synonym(s)
1.
Ibandronic Acid
2.
(1-Hydroxy-3-(methylpentylamino)propylidene)bisphosphonate
3.
1-Hydroxy-3-(methylpentylamino)propylidenebisphosphonate
4.
BM 21.0955
5.
BM 210955
6.
BM-21.0955
7.
BM-210955
8.
Bondronat
9.
Boniva
10.
Bonviva
11.
Ibandronate
12.
Ibandronate Sodium
13.
Ibandronate Sodium Anhydrous
14.
Ibandronic Acid, Sodium Salt, Monohydrate
15.
RPR 102289A
16.
RPR-102289A
17.
BM21.0955
18.
BM210955
19.
RPR102289A
External Link(s)
MeSHD000077557
PubChem Compound146015366
60852
BindingDB12577
CHEMBLCHEMBL997
DrugBankDB00710
DrugCentral1404
IUPHAR/BPS Guide to PHARMACOLOGY3059
KEGGdr:D08056
Therapeutic Target DatabaseD08SJZ
ZINC1533877
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1ArthralgiaFAERS: 392SIDER
US FAERS
2PainFAERS: 383OFFSIDES
SIDER
US FAERS
3MyalgiaFAERS: 279SIDER
US FAERS
4Back PainFAERS: 265SIDER
US FAERS
5Bone painFAERS: 247OFFSIDES
SIDER
US FAERS
6NauseaFAERS: 220OFFSIDES
SIDER
US FAERS
7DyspepsiaFAERS: 195OFFSIDES
SIDER
US FAERS
8HeadacheFAERS: 169SIDER
US FAERS
9No adverse eventFAERS: 154US FAERS
10MalaiseFAERS: 133SIDER
US FAERS
11Chest PainFAERS: 132OFFSIDES
SIDER
US FAERS
12Musculoskeletal PainFAERS: 129OFFSIDES
SIDER
US FAERS
13Abdominal discomfortFAERS: 117OFFSIDES
SIDER
US FAERS
14VomitingFAERS: 108SIDER
US FAERS
15Drug ineffectiveFAERS: 92US FAERS
16Osteonecrosis of JawFAERS: 90SIDER
US FAERS
17Wrong technique in product usage processFAERS: 90US FAERS
18DizzinessFAERS: 86SIDER
US FAERS
19Injection site extravasationFAERS: 78US FAERS
20FatigueFAERS: 68SIDER
US FAERS
21Peripheral swellingFAERS: 67US FAERS
22Drug dose omissionFAERS: 63US FAERS
23Bone density decreasedFAERS: 62US FAERS
24AstheniaFAERS: 57SIDER
US FAERS
25Abdominal PainFAERS: 54OFFSIDES
SIDER
US FAERS
26Neck PainFAERS: 53US FAERS
27PneumoniaFAERS: 52SIDER
US FAERS
28Myocardial InfarctionFAERS: 48US FAERS
29ChillsFAERS: 47SIDER
US FAERS
30Injection site painFAERS: 47SIDER
US FAERS
31Injection site erythemaFAERS: 43US FAERS
32OsteoporosisFAERS: 43OFFSIDES
US FAERS
33Cerebrovascular accidentFAERS: 42US FAERS
34Feeling abnormalFAERS: 42SIDER
US FAERS
35Tooth ExtractionFAERS: 42US FAERS
36ExtravasationFAERS: 40US FAERS
37HypersensitivityFAERS: 40SIDER
US FAERS
38SwellingFAERS: 40SIDER
US FAERS
39ConstipationFAERS: 39SIDER
US FAERS
40Musculoskeletal stiffnessFAERS: 38OFFSIDES
SIDER
US FAERS
41PruritusFAERS: 38SIDER
US FAERS
42AlopeciaFAERS: 36SIDER
US FAERS
43FlatulenceFAERS: 35OFFSIDES
SIDER
US FAERS
44FractureFAERS: 35SIDER
US FAERS
45Unevaluable eventFAERS: 35US FAERS
46Medication ErrorFAERS: 34US FAERS
47Oropharyngeal painFAERS: 34SIDER
US FAERS
48ToothacheFAERS: 34US FAERS
49ErythemaFAERS: 33SIDER
US FAERS
50ArthritisFAERS: 32OFFSIDES
SIDER
US FAERS
51Injection Site ReactionFAERS: 32SIDER
US FAERS
52Tooth LossFAERS: 32US FAERS
53Chest discomfortFAERS: 31US FAERS
54Burning sensationFAERS: 30OFFSIDES
US FAERS
55Weight decreasedFAERS: 30SIDER
US FAERS
56UrticariaFAERS: 29SIDER
US FAERS
57AnxietyFAERS: 27SIDER
US FAERS
58Drug administration errorFAERS: 27OFFSIDES
US FAERS
59Joint swellingFAERS: 27US FAERS
60Musculoskeletal chest painFAERS: 25OFFSIDES
US FAERS
61CellulitisFAERS: 24OFFSIDES
US FAERS
62Inappropriate schedule of drug administrationFAERS: 23US FAERS
63TremorFAERS: 23US FAERS
64Bone density abnormalFAERS: 22US FAERS
65InfluenzaFAERS: 22SIDER
US FAERS
66Injection site inflammationFAERS: 21OFFSIDES
US FAERS
67Product quality issueFAERS: 21US FAERS
68Dental cariesFAERS: 20US FAERS
69InfectionFAERS: 20SIDER
US FAERS
70OsteomyelitisFAERS: 20SIDER
US FAERS
71Urinary tract infectionFAERS: 20SIDER
US FAERS
72Visual ImpairmentFAERS: 20US FAERS
73GastritisFAERS: 19SIDER
US FAERS
74InflammationFAERS: 19SIDER
US FAERS
75Loose toothFAERS: 18US FAERS
76PhlebitisFAERS: 17US FAERS
77SinusitisFAERS: 17US FAERS
78ArthropathyFAERS: 16SIDER
US FAERS
79DysphoniaFAERS: 16US FAERS
80GingivitisFAERS: 16US FAERS
81UlcerFAERS: 16OFFSIDES
SIDER
US FAERS
82DehydrationFAERS: 15US FAERS
83Incorrect route of drug administrationFAERS: 15US FAERS
84ThrombosisFAERS: 15US FAERS
85Atypical femur fractureFAERS: 14SIDER
US FAERS
86DeafnessFAERS: 14SIDER
US FAERS
87DiscomfortFAERS: 14SIDER
US FAERS
88DysgeusiaFAERS: 14SIDER
US FAERS
89EructationFAERS: 14US FAERS
90NasopharyngitisFAERS: 14SIDER
US FAERS
91PalpitationsFAERS: 14SIDER
US FAERS
92SyncopeFAERS: 13US FAERS
93Throat irritationFAERS: 13US FAERS
94BronchitisFAERS: 12SIDER
US FAERS
95Epigastric discomfortFAERS: 12US FAERS
96Gastric ulcerFAERS: 12OFFSIDES
US FAERS
97General physical health deteriorationFAERS: 12US FAERS
98Infusion Site ExtravasationFAERS: 12US FAERS
99Injection site massFAERS: 12US FAERS
100Memory impairmentFAERS: 12US FAERS
101NephrolithiasisFAERS: 12US FAERS
102Respiratory FailureFAERS: 12US FAERS
103Tooth InfectionFAERS: 12US FAERS
104VertigoFAERS: 12SIDER
US FAERS
105AphoniaFAERS: 11US FAERS
106Atrial FibrillationFAERS: 11US FAERS
107Dental Restoration FailureFAERS: 11US FAERS
108Endodontic procedureFAERS: 11OFFSIDES
US FAERS
109OsteopeniaFAERS: 11SIDER
US FAERS
110AmnesiaFAERS: 10SIDER
US FAERS
111Emotional distressFAERS: 10US FAERS
112Joint stiffnessFAERS: 10OFFSIDES
US FAERS
113SomnolenceFAERS: 10US FAERS
114Back disorderFAERS: 9US FAERS
115Blood creatinine increasedFAERS: 9SIDER
US FAERS
116Cardiac ArrestFAERS: 9US FAERS
117Expired product administeredFAERS: 9US FAERS
118Feeling ColdFAERS: 9US FAERS
119Gingival RecessionFAERS: 9US FAERS
120GlaucomaFAERS: 9US FAERS
121OverdoseFAERS: 9US FAERS
122Pathological fractureFAERS: 9US FAERS
123Rheumatoid ArthritisFAERS: 9US FAERS
124StomatitisFAERS: 9SIDER
US FAERS
125TinnitusFAERS: 9US FAERS
126DementiaFAERS: 8US FAERS
127Failure to ThriveFAERS: 8OFFSIDES
US FAERS
128Foreign body in respiratory tractFAERS: 8US FAERS
129HypotensionFAERS: 8US FAERS
130Joint Range of Motion DecreasedFAERS: 8OFFSIDES
US FAERS
131Limb discomfortFAERS: 8US FAERS
132Oral painFAERS: 8US FAERS
133Pulmonary EmbolismFAERS: 8US FAERS
134Blood urine presentFAERS: 7US FAERS
135Diabetes MellitusFAERS: 7US FAERS
136Eye painFAERS: 7US FAERS
137Facial PainFAERS: 7US FAERS
138FibromyalgiaFAERS: 7US FAERS
139Gastrointestinal PainFAERS: 7SIDER
US FAERS
140HypophagiaFAERS: 7US FAERS
141LethargyFAERS: 7US FAERS
142Limb massFAERS: 7US FAERS
143Pancreatic carcinomaFAERS: 7US FAERS
144Procedural complicationFAERS: 7US FAERS
145Therapy non-responderFAERS: 7US FAERS
146TrismusFAERS: 7US FAERS
147AbscessFAERS: 6US FAERS
148Ankle FractureFAERS: 6US FAERS
149AsthmaFAERS: 6SIDER
US FAERS
150Atypical fractureFAERS: 6US FAERS
151Blood glucose decreasedFAERS: 6US FAERS
152Bone scan abnormalFAERS: 6US FAERS
153BursitisFAERS: 6OFFSIDES
US FAERS
154ChokingFAERS: 6US FAERS
155ColitisFAERS: 6OFFSIDES
US FAERS
156Compression fractureFAERS: 6OFFSIDES
US FAERS
157DysuriaFAERS: 6US FAERS
158Exposed bone in jawFAERS: 6US FAERS
159Gait inabilityFAERS: 6US FAERS
160Injection site bruisingFAERS: 6US FAERS
161Irritable Bowel SyndromeFAERS: 6US FAERS
162Loss of personal independence in daily activitiesFAERS: 6US FAERS
163Mouth swellingFAERS: 6US FAERS
164Muscle strainFAERS: 6OFFSIDES
US FAERS
165OsteolysisFAERS: 6US FAERS
166Post procedural complicationFAERS: 6US FAERS
167Productive CoughFAERS: 6US FAERS
168Respiratory arrestFAERS: 6US FAERS
169SepsisFAERS: 6US FAERS
170TachycardiaFAERS: 6US FAERS
171Therapy cessationFAERS: 6US FAERS
172ThrombophlebitisFAERS: 6OFFSIDES
US FAERS
173AngioedemaFAERS: 5OFFSIDES
SIDER
US FAERS
174Blood glucose increasedFAERS: 5US FAERS
175CataractFAERS: 5SIDER
US FAERS
176Cold sweatFAERS: 5US FAERS
177DisorientationFAERS: 5US FAERS
178Exostosis of jawFAERS: 5US FAERS
179Eye inflammationFAERS: 5US FAERS
180FlushingFAERS: 5US FAERS
181HerniaFAERS: 5OFFSIDES
US FAERS
182Lip swellingFAERS: 5US FAERS
183Low turnover osteopathyFAERS: 5US FAERS
184LymphadenopathyFAERS: 5US FAERS
185Malignant neoplasm progressionFAERS: 5US FAERS
186Muscle tightnessFAERS: 5OFFSIDES
US FAERS
187Musculoskeletal discomfortFAERS: 5SIDER
US FAERS
188NervousnessFAERS: 5US FAERS
189OnychoclasisFAERS: 5US FAERS
190OsteitisFAERS: 5US FAERS
191Renal painFAERS: 5US FAERS
192Septic ShockFAERS: 5US FAERS
193Vascular Access ComplicationFAERS: 5US FAERS
194Vascular ruptureFAERS: 5OFFSIDES
US FAERS
195AbasiaFAERS: 4US FAERS
196Anaphylactic shockFAERS: 4SIDER
US FAERS
197BedriddenFAERS: 4US FAERS
198Blood cholesterol increasedFAERS: 4US FAERS
199Blood sodium decreasedFAERS: 4US FAERS
200CalcinosisFAERS: 4US FAERS
201CholecystitisFAERS: 4US FAERS
202CystitisFAERS: 4SIDER
US FAERS
203Deep Vein ThrombosisFAERS: 4US FAERS
204Disease ProgressionFAERS: 4US FAERS
205Dry skinFAERS: 4US FAERS
206EpistaxisFAERS: 4US FAERS
207Eye irritationFAERS: 4US FAERS
208Gastrointestinal sounds abnormalFAERS: 4US FAERS
209Infusion site painFAERS: 4OFFSIDES
US FAERS
210Injection site discomfortFAERS: 4US FAERS
211Injection site irritationFAERS: 4US FAERS
212Injection site vesiclesFAERS: 4US FAERS
213Intentional product misuseFAERS: 4US FAERS
214LaryngitisFAERS: 4US FAERS
215Macular degenerationFAERS: 4US FAERS
216MarasmusFAERS: 4US FAERS
217Poor dental conditionFAERS: 4OFFSIDES
US FAERS
218RetchingFAERS: 4US FAERS
219ShockFAERS: 4SIDER
US FAERS
220SneezingFAERS: 4US FAERS
221StressFAERS: 4US FAERS
222Syringe issueFAERS: 4US FAERS
223ThirstFAERS: 4SIDER
US FAERS
224Vascular procedure complicationFAERS: 4US FAERS
225Walking aid userFAERS: 4US FAERS
226nervous system disorderFAERS: 4SIDER
US FAERS
227ActinomycosisFAERS: 3US FAERS
228Activities of daily living impairedFAERS: 3US FAERS
229Angina PectorisFAERS: 3US FAERS
230Aortic Valve StenosisFAERS: 3US FAERS
231Bone fissureFAERS: 3US FAERS
232CholelithiasisFAERS: 3SIDER
US FAERS
233Coronary Artery DiseaseFAERS: 3US FAERS
234CryingFAERS: 3US FAERS
235DysarthriaFAERS: 3US FAERS
236GoutFAERS: 3US FAERS
237HypokinesiaFAERS: 3US FAERS
238HypothyroidismFAERS: 3US FAERS
239ImmobileFAERS: 3OFFSIDES
US FAERS
240Impaired work abilityFAERS: 3US FAERS
241Incorrect drug administration durationFAERS: 3US FAERS
242Infusion site swellingFAERS: 3OFFSIDES
US FAERS
243Injection site necrosisFAERS: 3US FAERS
244Limb injuryFAERS: 3US FAERS
245Lower respiratory tract infectionFAERS: 3US FAERS
246Muscle FatigueFAERS: 3OFFSIDES
US FAERS
247NecrosisFAERS: 3US FAERS
248Oropharyngeal discomfortFAERS: 3SIDER
US FAERS
249PancreatitisFAERS: 3US FAERS
250PancytopeniaFAERS: 3US FAERS
251PneumonitisFAERS: 3US FAERS
252Polymyalgia RheumaticaFAERS: 3OFFSIDES
US FAERS
253Poor quality drug administeredFAERS: 3US FAERS
254PresyncopeFAERS: 3US FAERS
255Pulmonary HypertensionFAERS: 3US FAERS
256RegurgitationFAERS: 3OFFSIDES
US FAERS
257Renal ColicFAERS: 3OFFSIDES
US FAERS
258SciaticaFAERS: 3US FAERS
259Spinal column stenosisFAERS: 3US FAERS
260SpondylitisFAERS: 3OFFSIDES
US FAERS
261Sudden deathFAERS: 3OFFSIDES
US FAERS
262Thermal burnFAERS: 3US FAERS
263ThrombocytopeniaFAERS: 3US FAERS
264Upper-airway cough syndromeFAERS: 3US FAERS
265Urinary RetentionFAERS: 3SIDER
US FAERS
266VasculitisFAERS: 3US FAERS
267White blood cell count decreasedFAERS: 3US FAERS
268treatment failureFAERS: 3US FAERS
269Acute respiratory failureFAERS: 2US FAERS
270AdenocarcinomaFAERS: 2US FAERS
271Administration site reactionFAERS: 2US FAERS
272Administration site warmthFAERS: 2US FAERS
273Adverse eventFAERS: 2US FAERS
274AnorexiaFAERS: 2US FAERS
275AphasiaFAERS: 2US FAERS
276AppendicitisFAERS: 2OFFSIDES
US FAERS
277Artificial crown procedureFAERS: 2US FAERS
278AstigmatismFAERS: 2US FAERS
279Blood calcium abnormalFAERS: 2US FAERS
280Blood creatinine abnormalFAERS: 2US FAERS
281Blood potassium decreasedFAERS: 2US FAERS
282Bone decalcificationFAERS: 2US FAERS
283Bone fragmentationFAERS: 2OFFSIDES
US FAERS
284Bone swellingFAERS: 2US FAERS
285Bronchial HyperreactivityFAERS: 2US FAERS
286Cardiac FlutterFAERS: 2US FAERS
287Carpal Tunnel SyndromeFAERS: 2US FAERS
288Cerebral InfarctionFAERS: 2US FAERS
289Choking sensationFAERS: 2US FAERS
290CystFAERS: 2US FAERS
291DeliriumFAERS: 2US FAERS
292Dental prosthesis placementFAERS: 2US FAERS
293Depressed moodFAERS: 2OFFSIDES
US FAERS
294DermatitisFAERS: 2SIDER
US FAERS
295Device breakageFAERS: 2US FAERS
296Disease recurrenceFAERS: 2US FAERS
297Duodenal UlcerFAERS: 2SIDER
US FAERS
298Ear discomfortFAERS: 2OFFSIDES
US FAERS
299EczemaFAERS: 2US FAERS
300EnterocolitisFAERS: 2US FAERS
301Feeling of body temperature changeFAERS: 2US FAERS
302Gamma-Glutamyltransferase IncreasedFAERS: 2SIDER
US FAERS
303Gastric infectionFAERS: 2OFFSIDES
US FAERS
304Gastrointestinal motility disorderFAERS: 2US FAERS
305Gluten sensitivityFAERS: 2US FAERS
306Head discomfortFAERS: 2US FAERS
307HungerFAERS: 2US FAERS
308HyperchlorhydriaFAERS: 2US FAERS
309Hypertensive crisisFAERS: 2US FAERS
310HyperthyroidismFAERS: 2US FAERS
311HysterectomyFAERS: 2OFFSIDES
US FAERS
312IleusFAERS: 2US FAERS
313Immune thrombocytopenic purpuraFAERS: 2US FAERS
314Impaired driving abilityFAERS: 2US FAERS
315IncontinenceFAERS: 2US FAERS
316Incorrect dose administeredFAERS: 2US FAERS
317Incorrect route of product administrationFAERS: 2US FAERS
318IndurationFAERS: 2US FAERS
319InfarctionFAERS: 2US FAERS
320Infusion site erythemaFAERS: 2OFFSIDES
US FAERS
321Injection related reactionFAERS: 2US FAERS
322Injection site cellulitisFAERS: 2OFFSIDES
US FAERS
323Injection site pruritusFAERS: 2US FAERS
324Intentional product use issueFAERS: 2US FAERS
325Intervertebral Disc DegenerationFAERS: 2US FAERS
326Intestinal FistulaFAERS: 2US FAERS
327Intestinal ObstructionFAERS: 2US FAERS
328Intestinal resectionFAERS: 2US FAERS
329Intracranial AneurysmFAERS: 2US FAERS
330IritisFAERS: 2OFFSIDES
SIDER
US FAERS
331LymphoceleFAERS: 2US FAERS
332MalnutritionFAERS: 2SIDER
US FAERS
333Meniscus injuryFAERS: 2US FAERS
334Mental impairmentFAERS: 2US FAERS
335MesotheliomaFAERS: 2US FAERS
336Metabolic acidosisFAERS: 2US FAERS
337Metastatic NeoplasmFAERS: 2OFFSIDES
US FAERS
338Multiple SclerosisFAERS: 2US FAERS
339Muscle RigidityFAERS: 2US FAERS
340MyopiaFAERS: 2US FAERS
341Needle issueFAERS: 2US FAERS
342NeuralgiaFAERS: 2SIDER
US FAERS
343OnycholysisFAERS: 2US FAERS
344Oral Cavity FistulaFAERS: 2US FAERS
345Oropharyngeal plaqueFAERS: 2US FAERS
346OsteochondrosisFAERS: 2OFFSIDES
US FAERS
347Paranasal sinus hypersecretionFAERS: 2US FAERS
348Pelvic PainFAERS: 2SIDER
US FAERS
349Pericardial effusionFAERS: 2US FAERS
350PeriodontitisFAERS: 2US FAERS
351PeritonitisFAERS: 2US FAERS
352PlasmacytomaFAERS: 2OFFSIDES
US FAERS
353Product outer packaging issueFAERS: 2US FAERS
354Product storage errorFAERS: 2US FAERS
355Pulmonary thrombosisFAERS: 2OFFSIDES
US FAERS
356PurulenceFAERS: 2US FAERS
357Purulent dischargeFAERS: 2US FAERS
358Renal cystFAERS: 2SIDER
US FAERS
359Respiratory distressFAERS: 2US FAERS
360SeromaFAERS: 2US FAERS
361Skin lesionFAERS: 2US FAERS
362Spinal column injuryFAERS: 2US FAERS
363TachyarrhythmiaFAERS: 2US FAERS
364Temperature intoleranceFAERS: 2US FAERS
365Tongue discomfortFAERS: 2US FAERS
366Toxicity to various agentsFAERS: 2US FAERS
367Trigeminal NeuralgiaFAERS: 2US FAERS
368Urinary Tract PainFAERS: 2OFFSIDES
US FAERS
369UveitisFAERS: 2SIDER
US FAERS
370Venous ThrombosisFAERS: 2US FAERS
371Wound InfectionFAERS: 2US FAERS
372Wrong technique in drug usage processFAERS: 2US FAERS
373Abdominal rigidityFAERS: 1US FAERS
374Abdominal strangulated herniaFAERS: 1US FAERS
375Abdominal tendernessFAERS: 1US FAERS
376Accidental exposure to productFAERS: 1US FAERS
377Accidental overdoseFAERS: 1US FAERS
378AcidosisFAERS: 1US FAERS
379AcneFAERS: 1US FAERS
380Acoustic NeuromaFAERS: 1US FAERS
381Acute Coronary SyndromeFAERS: 1US FAERS
382Acute kidney injuryFAERS: 1US FAERS
383Administration site abscessFAERS: 1US FAERS
384Administration site erythemaFAERS: 1US FAERS
385Administration site extravasationFAERS: 1US FAERS
386Administration site indurationFAERS: 1US FAERS
387Administration site swellingFAERS: 1US FAERS
388AgeusiaFAERS: 1US FAERS
389AgitationFAERS: 1US FAERS
390Alanine Aminotransferase IncreasedFAERS: 1US FAERS
391Allergic sinusitisFAERS: 1US FAERS
392Altered state of consciousnessFAERS: 1US FAERS
393Anal inflammationFAERS: 1US FAERS
394Anaphylactoid ReactionFAERS: 1US FAERS
395Angular cheilitisFAERS: 1US FAERS
396AnosmiaFAERS: 1US FAERS
397Anoxic EncephalopathyFAERS: 1US FAERS
398AnuriaFAERS: 1US FAERS
399Aortic AneurysmFAERS: 1US FAERS
400Aortic RuptureFAERS: 1US FAERS
401AphagiaFAERS: 1OFFSIDES
US FAERS
402Application site erythemaFAERS: 1US FAERS
403ArachnoiditisFAERS: 1US FAERS
404ArteriosclerosisFAERS: 1US FAERS
405Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
406Atrioventricular BlockFAERS: 1US FAERS
407Atypical pneumoniaFAERS: 1US FAERS
408AuraFAERS: 1US FAERS
409Benign neoplasm of thyroid glandFAERS: 1US FAERS
410Biliary dilatationFAERS: 1US FAERS
411Bladder prolapseFAERS: 1US FAERS
412BlindnessFAERS: 1US FAERS
413Blood alkaline phosphatase increasedFAERS: 1US FAERS
414Blood cholesterol abnormalFAERS: 1OFFSIDES
US FAERS
415Blood count abnormalFAERS: 1US FAERS
416Blood creatine phosphokinase increasedFAERS: 1US FAERS
417Blood electrolytes abnormalFAERS: 1US FAERS
418Blood glucose abnormalFAERS: 1US FAERS
419Blood lactate dehydrogenase increasedFAERS: 1US FAERS
420Blood magnesium increasedFAERS: 1US FAERS
421Blood parathyroid hormone abnormalFAERS: 1US FAERS
422Blood parathyroid hormone increasedFAERS: 1SIDER
US FAERS
423Blood phosphorus decreasedFAERS: 1US FAERS
424Blood phosphorus increasedFAERS: 1US FAERS
425Blood potassium increasedFAERS: 1US FAERS
426Blood triglycerides increasedFAERS: 1US FAERS
427Blood urea increasedFAERS: 1US FAERS
428Bone atrophyFAERS: 1US FAERS
429Bone erosionFAERS: 1OFFSIDES
US FAERS
430Bone fistulaFAERS: 1US FAERS
431Bowel movement irregularityFAERS: 1US FAERS
432BradycardiaFAERS: 1US FAERS
433Brain stem syndromeFAERS: 1US FAERS
434Breast CystFAERS: 1US FAERS
435Breast infectionFAERS: 1US FAERS
436Breast tendernessFAERS: 1US FAERS
437BronchopneumoniaFAERS: 1OFFSIDES
US FAERS
438BronchospasmFAERS: 1SIDER
US FAERS
439BruxismFAERS: 1US FAERS
440Bulimia NervosaFAERS: 1US FAERS
441Burning Mouth SyndromeFAERS: 1US FAERS
442Cardiac neoplasm unspecifiedFAERS: 1US FAERS
443Cartilage atrophyFAERS: 1US FAERS
444Cataract operationFAERS: 1US FAERS
445Catheter placementFAERS: 1US FAERS
446CheilitisFAERS: 1SIDER
US FAERS
447Chemical burn of skinFAERS: 1US FAERS
448ChromaturiaFAERS: 1OFFSIDES
US FAERS
449Circumstance or information capable of leading to medication errorFAERS: 1US FAERS
450Clostridium difficile infectionFAERS: 1US FAERS
451Colon cancer recurrentFAERS: 1OFFSIDES
US FAERS
452Complications of transplant surgeryFAERS: 1US FAERS
453Corrective lens userFAERS: 1US FAERS
454Creatinine renal clearance decreasedFAERS: 1US FAERS
455CytopeniaFAERS: 1US FAERS
456DactylitisFAERS: 1OFFSIDES
US FAERS
457DeformityFAERS: 1US FAERS
458Dengue FeverFAERS: 1OFFSIDES
US FAERS
459Dental FistulaFAERS: 1US FAERS
460Depressed Level of ConsciousnessFAERS: 1US FAERS
461Device expulsionFAERS: 1US FAERS
462Device related infectionFAERS: 1US FAERS
463Device toxicityFAERS: 1US FAERS
464Diabetic RetinopathyFAERS: 1US FAERS
465Diffuse Large B-Cell LymphomaFAERS: 1US FAERS
466Diffuse vasculitisFAERS: 1US FAERS
467Disease susceptibilityFAERS: 1US FAERS
468DiverticulitisFAERS: 1US FAERS
469DiverticulumFAERS: 1US FAERS
470Drug ToleranceFAERS: 1US FAERS
471Drug prescribing errorFAERS: 1US FAERS
472DyscheziaFAERS: 1OFFSIDES
US FAERS
473DysenteryFAERS: 1US FAERS
474Electromechanical dissociationFAERS: 1US FAERS
475EmbolismFAERS: 1US FAERS
476Endoscopy upper gastrointestinal tract abnormalFAERS: 1US FAERS
477Eosinophilic FasciitisFAERS: 1US FAERS
478Epidermal necrosisFAERS: 1US FAERS
479Erythema MultiformeFAERS: 1US FAERS
480Erythema NodosumFAERS: 1US FAERS
481Eye InfectionFAERS: 1US FAERS
482Facial NeuralgiaFAERS: 1OFFSIDES
US FAERS
483Facial paralysisFAERS: 1US FAERS
484Failure of implantFAERS: 1OFFSIDES
US FAERS
485Feeling jitteryFAERS: 1US FAERS
486Flank PainFAERS: 1US FAERS
487Foreign body sensation in eyesFAERS: 1OFFSIDES
US FAERS
488Fracture painFAERS: 1US FAERS
489Fracture treatmentFAERS: 1US FAERS
490Frustration tolerance decreasedFAERS: 1US FAERS
491FrustrationFAERS: 1US FAERS
492Full blood count decreasedFAERS: 1OFFSIDES
US FAERS
493Gallbladder painFAERS: 1US FAERS
494GammopathyFAERS: 1US FAERS
495GangreneFAERS: 1US FAERS
496Gastric DilatationFAERS: 1US FAERS
497GastroenteritisFAERS: 1SIDER
US FAERS
498Gastrointestinal infectionFAERS: 1US FAERS
499Gastrointestinal ulcerFAERS: 1US FAERS
500Gastrointestinal viral infectionFAERS: 1US FAERS
501General physical condition abnormalFAERS: 1US FAERS
502Gingival erythemaFAERS: 1US FAERS
503GlossitisFAERS: 1OFFSIDES
US FAERS
504Glossopharyngeal NeuralgiaFAERS: 1US FAERS
505GranulomaFAERS: 1OFFSIDES
US FAERS
506Grief reactionFAERS: 1US FAERS
507Head titubationFAERS: 1US FAERS
508Hepatic cancer metastaticFAERS: 1US FAERS
509HepatitisFAERS: 1US FAERS
510HepatomegalyFAERS: 1US FAERS
511HomicideFAERS: 1US FAERS
512HyperparathyroidismFAERS: 1US FAERS
513HypersomniaFAERS: 1US FAERS
514ImmunosuppressionFAERS: 1US FAERS
515Impaired gastric emptyingFAERS: 1US FAERS
516Implant site inflammationFAERS: 1US FAERS
517Implant site painFAERS: 1US FAERS
518IncoherentFAERS: 1US FAERS
519Incorrect drug administration rateFAERS: 1US FAERS
520Increased upper airway secretionFAERS: 1US FAERS
521Infusion site indurationFAERS: 1US FAERS
522Infusion site inflammationFAERS: 1US FAERS
523Infusion site reactionFAERS: 1US FAERS
524Injection site cystFAERS: 1US FAERS
525Injection site hypersensitivityFAERS: 1US FAERS
526Injection site infectionFAERS: 1US FAERS
527Injection site joint inflammationFAERS: 1US FAERS
528Injection site movement impairmentFAERS: 1US FAERS
529Injection site noduleFAERS: 1US FAERS
530Injection site phlebitisFAERS: 1US FAERS
531Injection site thrombosisFAERS: 1OFFSIDES
US FAERS
532Injection site warmthFAERS: 1US FAERS
533Injury associated with deviceFAERS: 1US FAERS
534Intentional self-injuryFAERS: 1US FAERS
535Intercepted drug administration errorFAERS: 1US FAERS
536Intercepted medication errorFAERS: 1US FAERS
537Intercepted product storage errorFAERS: 1US FAERS
538Intervertebral disc disorderFAERS: 1US FAERS
539Investigation abnormalFAERS: 1US FAERS
540Joint InstabilityFAERS: 1US FAERS
541Joint injuryFAERS: 1US FAERS
542KeratitisFAERS: 1US FAERS
543LacerationFAERS: 1US FAERS
544Lactose IntoleranceFAERS: 1US FAERS
545LaparotomyFAERS: 1US FAERS
546LazinessFAERS: 1US FAERS
547LeukopeniaFAERS: 1US FAERS
548Lichen PlanusFAERS: 1US FAERS
549Limb crushing injuryFAERS: 1US FAERS
550Lower respiratory tract congestionFAERS: 1US FAERS
551Lymph Node TuberculosisFAERS: 1US FAERS
552MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
553MaculeFAERS: 1US FAERS
554MalabsorptionFAERS: 1US FAERS
555Mastication disorderFAERS: 1US FAERS
556Masticatory painFAERS: 1US FAERS
557Maternal exposure before pregnancyFAERS: 1US FAERS
558Mechanical ventilationFAERS: 1US FAERS
559Medial Tibial Stress SyndromeFAERS: 1US FAERS
560Medical device implantationFAERS: 1US FAERS
561MeningiomaFAERS: 1US FAERS
562Mesenteric PanniculitisFAERS: 1US FAERS
563MetastasisFAERS: 1US FAERS
564Metastatic painFAERS: 1US FAERS
565MonoplegiaFAERS: 1OFFSIDES
US FAERS
566Motion SicknessFAERS: 1US FAERS
567Multi-organ disorderFAERS: 1US FAERS
568Multiple MyelomaFAERS: 1US FAERS
569Multiple sclerosis relapseFAERS: 1US FAERS
570Muscle SpasticityFAERS: 1US FAERS
571MyelitisFAERS: 1OFFSIDES
US FAERS
572MyocarditisFAERS: 1US FAERS
573Myositis OssificansFAERS: 1US FAERS
574Nasal discomfortFAERS: 1US FAERS
575Nephrotic SyndromeFAERS: 1US FAERS
576Nerve injuryFAERS: 1US FAERS
577Night sweatsFAERS: 1US FAERS
578Nodal osteoarthritisFAERS: 1US FAERS
579NoduleFAERS: 1US FAERS
580Non-cardiac chest painFAERS: 1US FAERS
581Nonspecific reactionFAERS: 1US FAERS
582ObstructionFAERS: 1US FAERS
583Occupational exposure to productFAERS: 1US FAERS
584Ocular discomfortFAERS: 1US FAERS
585OnychalgiaFAERS: 1OFFSIDES
US FAERS
586Oral candidiasisFAERS: 1SIDER
US FAERS
587Oral infectionFAERS: 1US FAERS
588Oropharyngeal spasmFAERS: 1OFFSIDES
US FAERS
589Osteogenesis ImperfectaFAERS: 1OFFSIDES
US FAERS
590Oxygen saturation abnormalFAERS: 1US FAERS
591Pain of skinFAERS: 1US FAERS
592PallorFAERS: 1US FAERS
593Palmar erythemaFAERS: 1US FAERS
594Palpable purpuraFAERS: 1US FAERS
595PanniculitisFAERS: 1US FAERS
596PanophthalmitisFAERS: 1SIDER
US FAERS
597Paradoxical drug reactionFAERS: 1US FAERS
598ParaparesisFAERS: 1US FAERS
599ParophthalmiaFAERS: 1US FAERS
600Peptic UlcerFAERS: 1US FAERS
601PeriarthritisFAERS: 1US FAERS
602Periorbital disorderFAERS: 1US FAERS
603Peripheral venous diseaseFAERS: 1US FAERS
604PetechiaeFAERS: 1US FAERS
605Pharyngeal pouchFAERS: 1US FAERS
606PhotophobiaFAERS: 1US FAERS
607Physical deconditioningFAERS: 1US FAERS
608PolyneuropathyFAERS: 1OFFSIDES
US FAERS
609PolyuriaFAERS: 1US FAERS
610Poor peripheral circulationFAERS: 1US FAERS
611Poor quality sleepFAERS: 1US FAERS
612Post procedural inflammationFAERS: 1US FAERS
613Post-Traumatic Stress DisorderFAERS: 1US FAERS
614Postoperative abscessFAERS: 1US FAERS
615Postoperative ileusFAERS: 1US FAERS
616PregnancyFAERS: 1US FAERS
617Primary Biliary CholangitisFAERS: 1US FAERS
618Procedural site reactionFAERS: 1US FAERS
619Product dose omissionFAERS: 1US FAERS
620Product package associated injuryFAERS: 1US FAERS
621Product packaging issueFAERS: 1US FAERS
622Product physical issueFAERS: 1US FAERS
623Product substitution issueFAERS: 1US FAERS
624Product use in unapproved indicationFAERS: 1US FAERS
625Product use issueFAERS: 1US FAERS
626Prosthesis ImplantationFAERS: 1US FAERS
627Protein urine presentFAERS: 1US FAERS
628Pulmonary FibrosisFAERS: 1US FAERS
629Pulmonary painFAERS: 1US FAERS
630Pyoderma GangrenosumFAERS: 1US FAERS
631Quality of life decreasedFAERS: 1OFFSIDES
US FAERS
632Radial nerve compressionFAERS: 1US FAERS
633Rapidly progressive osteoarthritisFAERS: 1US FAERS
634Rash erythematousFAERS: 1SIDER
US FAERS
635Renal tubular necrosisFAERS: 1US FAERS
636Respiratory depth decreasedFAERS: 1US FAERS
637RestlessnessFAERS: 1US FAERS
638Retinal DetachmentFAERS: 1US FAERS
639Retinal vascular thrombosisFAERS: 1US FAERS
640RhinitisFAERS: 1US FAERS
641Rotator cuff syndromeFAERS: 1US FAERS
642ScabFAERS: 1OFFSIDES
US FAERS
643SclerodermaFAERS: 1OFFSIDES
US FAERS
644SequestrectomyFAERS: 1US FAERS
645Sinus headacheFAERS: 1US FAERS
646Skin UlcerFAERS: 1US FAERS
647Skin WrinklingFAERS: 1US FAERS
648Skin discomfortFAERS: 1US FAERS
649Skin irritationFAERS: 1US FAERS
650Skin lacerationFAERS: 1US FAERS
651Skin necrosisFAERS: 1US FAERS
652Skin reactionFAERS: 1US FAERS
653Sleep disorder due to a general medical conditionFAERS: 1US FAERS
654Soft Tissue InfectionFAERS: 1US FAERS
655Splenic RuptureFAERS: 1US FAERS
656Stevens-Johnson SyndromeFAERS: 1US FAERS
657Subcutaneous AbscessFAERS: 1US FAERS
658Sudden Cardiac DeathFAERS: 1US FAERS
659Surgical failureFAERS: 1US FAERS
660SynovitisFAERS: 1US FAERS
661Systemic lupus erythematosus rashFAERS: 1US FAERS
662Teeth brittleFAERS: 1OFFSIDES
US FAERS
663TetanyFAERS: 1US FAERS
664Therapy responderFAERS: 1US FAERS
665Thyroid NeoplasmFAERS: 1US FAERS
666ThyroidectomyFAERS: 1US FAERS
667Toe operationFAERS: 1US FAERS
668Tooth AvulsionFAERS: 1US FAERS
669TorticollisFAERS: 1US FAERS
670Transaminases increasedFAERS: 1US FAERS
671Typhoid FeverFAERS: 1US FAERS
672Upper respiratory tract congestionFAERS: 1US FAERS
673Urinary IncontinenceFAERS: 1US FAERS
674Uterine PolypFAERS: 1US FAERS
675Vaginal DischargeFAERS: 1US FAERS
676VasospasmFAERS: 1US FAERS
677Venous InsufficiencyFAERS: 1US FAERS
678Ventricular arrhythmiaFAERS: 1US FAERS
679Vessel puncture site bruiseFAERS: 1US FAERS
680Viral pharyngitisFAERS: 1US FAERS
681Visual brightnessFAERS: 1US FAERS
682Visual disturbanceFAERS: 1US FAERS
683Vitreous DetachmentFAERS: 1OFFSIDES
US FAERS
684Vitreous floatersFAERS: 1US FAERS
685Vitreous lossFAERS: 1US FAERS
686Vocal Cord DysfunctionFAERS: 1US FAERS
687Vulvovaginal burning sensationFAERS: 1US FAERS
688Vulvovaginal drynessFAERS: 1US FAERS
689Waist circumference increasedFAERS: 1US FAERS
690Wheelchair userFAERS: 1US FAERS
691WheezingFAERS: 1US FAERS
692Wound ComplicationFAERS: 1US FAERS
693Wound dehiscenceFAERS: 1US FAERS
694Wrong drug administeredFAERS: 1US FAERS
695cancer surgeryFAERS: 1US FAERS
696jaundiceFAERS: 1US FAERS
697keratoacanthomaFAERS: 1US FAERS
698skin abrasionFAERS: 1US FAERS
699Abdominal symptomOFFSIDES
700AcholiaOFFSIDES
701Acid refluxOFFSIDES
702Allergy to animalOFFSIDES
703Alopecia effluviumOFFSIDES
704Alopecia totalisOFFSIDES
705Androgenetic AlopeciaOFFSIDES
706Angle Closure GlaucomaOFFSIDES
707Animal biteOFFSIDES
708Anti-erythropoietin antibody positiveOFFSIDES
709Aortic valve calcificationOFFSIDES
710Aortic valve sclerosisOFFSIDES
711AppendectomyOFFSIDES
712ArteritisOFFSIDES
713Atrial FlutterOFFSIDES
714Atrophic vulvovaginitisOFFSIDES
715Autoimmune hepatitisOFFSIDES
716AversionOFFSIDES
717Avoidant Personality DisorderOFFSIDES
718Axonal neuropathyOFFSIDES
719Benign NeoplasmOFFSIDES
720Benign bone neoplasmOFFSIDES
721Benign neoplasm of skinSIDER
722Biopsy site unspecified abnormalOFFSIDES
723Bladder painSIDER
724BlepharitisOFFSIDES
725BlepharospasmOFFSIDES
726Blood 1,25-dihydroxycholecalciferol decreasedOFFSIDES
727Blood amylase decreasedOFFSIDES
728Blood and lymphatic system disordersSIDER
729Blood cholinesterase decreasedOFFSIDES
730Blood electrolytes decreasedOFFSIDES
731Blood immunoglobulin EOFFSIDES
732Bone infarctionOFFSIDES
733Bone trimmingOFFSIDES
734Breast cancer recurrentOFFSIDES
735Breast fibromaOFFSIDES
736BronchoconstrictionSIDER
737Bulbar palsyOFFSIDES
738Candida sepsisOFFSIDES
739Cardiac imaging procedure normalOFFSIDES
740Cardiac valve replacement complicationOFFSIDES
741Cervix carcinoma stage IVOFFSIDES
742Chronic ulcerative colitisOFFSIDES
743Circumoral paresthesiaSIDER
744Clostridium difficile toxin test positiveOFFSIDES
745Congenital tricuspid valve incompetenceOFFSIDES
746Creatinine increasedSIDER
747Cytomegalovirus test positiveOFFSIDES
748Dental abscessOFFSIDES
749Dependent Personality DisorderOFFSIDES
750Diabetic NephropathyOFFSIDES
751DiarrheaOFFSIDES
752Disease complicationOFFSIDES
753Drug level fluctuatingOFFSIDES
754Drug specific antibody presentOFFSIDES
755Drug withdrawal headacheOFFSIDES
756DuodenitisSIDER
757DyslexiaOFFSIDES
758Ear and labyrinth disordersSIDER
759Ear congestionOFFSIDES
760EcchymosisSIDER
761Economic problemOFFSIDES
762Enamel anomalyOFFSIDES
763Endometrial hypertrophyOFFSIDES
764EndophthalmitisSIDER
765EnteritisOFFSIDES
766Enterococcal infectionOFFSIDES
767Epidural AbscessOFFSIDES
768Epidural lipomatosisOFFSIDES
769EpiscleritisSIDER
770Erythema InfectiosumOFFSIDES
771Escherichia infectionOFFSIDES
772Esophageal PerforationOFFSIDES
773Esophageal StenosisOFFSIDES
774Eustachian tube disorderOFFSIDES
775Exacerbation of asthmaSIDER
776Extremity contractureOFFSIDES
777Eye laser surgeryOFFSIDES
778Factor V deficiencyOFFSIDES
779Femoral pulse decreasedOFFSIDES
780Focal glomerulosclerosisOFFSIDES
781Food AllergyOFFSIDES
782Foreign body traumaOFFSIDES
783GastroduodenitisOFFSIDES
784Gastrooesophageal cancerOFFSIDES
785General symptomOFFSIDES
786Genital HerpesOFFSIDES
787GlomerulonephritisOFFSIDES
788Granuloma AnnulareOFFSIDES
789Guttate psoriasisOFFSIDES
790Hand repair operationOFFSIDES
791Hepatic vein stenosisOFFSIDES
792Hypertensive heart diseaseOFFSIDES
793Hypopharyngeal CancerOFFSIDES
794ImpetigoOFFSIDES
795InfestationSIDER
796Influenza-like symptomsSIDER
797Infusion site mobility decreasedOFFSIDES
798Infusion site necrosisOFFSIDES
799Infusion site phlebitisOFFSIDES
800Injection site injuryOFFSIDES
801Klebsiella sepsisOFFSIDES
802Latex allergyOFFSIDES
803Libido disorderOFFSIDES
804Lip exfoliationOFFSIDES
805Liver AbscessOFFSIDES
806Local reactionSIDER
807Lower respiratory tract infection fungalOFFSIDES
808Mallory-Weiss SyndromeOFFSIDES
809MalocclusionOFFSIDES
810MelanosisOFFSIDES
811Metastatic Renal Cell CarcinomaOFFSIDES
812Micturition frequency decreasedOFFSIDES
813Motor retardationOFFSIDES
814NephrectasiaOFFSIDES
815Nerve Root CompressionOFFSIDES
816Nerve root lesionSIDER
817Neuromyelitis OpticaOFFSIDES
818No adverse effectOFFSIDES
819Non-small cell lung cancer stage IOFFSIDES
820Open reduction of fractureOFFSIDES
821Orthostatic hypertensionOFFSIDES
822Osteitis DeformansOFFSIDES
823Osteoma cutisOFFSIDES
824Pain, Intractable15337809CTD
825Paranoid Personality DisorderOFFSIDES
826Parotid duct obstructionOFFSIDES
827Peripheral paralysisOFFSIDES
828PharyngitisSIDER
829Pharyngolaryngeal PainOFFSIDES
830Pharyngolaryngeal discomfortOFFSIDES
831Pigmentary retinopathyOFFSIDES
832PorokeratosisOFFSIDES
833Post procedural fistulaOFFSIDES
834Post procedural infectionOFFSIDES
835Post procedural swellingOFFSIDES
836Post-traumatic painOFFSIDES
837Prolonged expirationOFFSIDES
838PrurigoSIDER
839Pruritus allergicOFFSIDES
840PseudocystOFFSIDES
841Punctate keratitisOFFSIDES
842Pyogenic granulomaOFFSIDES
843Radiation mucositisOFFSIDES
844RadiculopathySIDER
845RednessSIDER
846Respiratory tract infection bacterialOFFSIDES
847Respiratory tract irritationOFFSIDES
848Retinal artery embolismOFFSIDES
849Revision of internal fixationOFFSIDES
850Rheumatoid NoduleOFFSIDES
851SacroiliitisOFFSIDES
852Salivary Gland FistulaOFFSIDES
853Sarcoma of skinOFFSIDES
854Scan bone marrow abnormalOFFSIDES
855Scan lymph nodesOFFSIDES
856ScleritisOFFSIDES
SIDER
857Serum calcium decreasedSIDER
858Shoulder PainOFFSIDES
859Skeletal injuryOFFSIDES
860Sleep disorder due to general medical condition, insomnia typeOFFSIDES
861Splenic granulomaOFFSIDES
862SpondylolysisOFFSIDES
863StarvationOFFSIDES
864StridorSIDER
865Suture related complicationOFFSIDES
866SweatingSIDER
867SynovectomyOFFSIDES
868Systolic hypertensionOFFSIDES
869T-lymphocyte count increasedOFFSIDES
870Temporal ArteritisOFFSIDES
871TenosynovitisOFFSIDES
872ThelitisOFFSIDES
873Tinea PedisOFFSIDES
874Tinea crurisOFFSIDES
875Tobacco withdrawal symptomsOFFSIDES
876Tooth ErosionOFFSIDES
877TraumaSIDER
878TrichiasisOFFSIDES
879Trigeminal Nerve DisorderOFFSIDES
880UremiaSIDER
881Urinary tract infection pseudomonalOFFSIDES
882Urine calcium decreasedOFFSIDES
883Uterine stenosisOFFSIDES
884Vaginal burning sensationOFFSIDES
885Varicose vein operationOFFSIDES
886Venous InjuryOFFSIDES
887Very low density lipoprotein increasedOFFSIDES
888Vestibular NeuronitisOFFSIDES
889Violence-related symptomOFFSIDES
890White blood cells stool positiveOFFSIDES
891Wound infection staphylococcalOFFSIDES
892carbuncleOFFSIDES
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