MetaADEDB 2.0 @ LMMD
Mefloquine
(XEEQGYMUWCZPDN-UHFFFAOYSA-N)
Structure
SMILES
OC(c1cc(nc2c1cccc2C(F)(F)F)C(F)(F)F)C1CCCCN1
Type(s)
Approved; Investigational
ATC code(s)
P01BC02; P01BF02
Molecular Formula:
C17H16F6N2O
Molecular Weight:
378.312
Log P:
4.7767
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
2
TPSA:
45.15
CAS Number(s):
49752-90-1; 53230-10-7
Synonym(s)
1.
Mefloquine
2.
Lariam
3.
Mefloquine Hydrochloride
4.
Mephloquine
5.
Ro-21-5998-001
6.
WR-142,490
7.
WR-177,602
8.
Ro 21 5998 001
9.
Ro215998001
10.
WR 142,490
11.
WR 177,602
12.
WR142,490
13.
WR177,602
External Link(s)
MeSHD015767
PubChem Compound4046
BindingDB50022889
ChEBI63681
CHEMBLCHEMBL416956
DrugBankDB00358
IUPHAR/BPS Guide to PHARMACOLOGY4252
KEGGcpd:C07633
dr:D04895
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1AnxietyFAERS: 190US FAERS
2FatigueFAERS: 87US FAERS
3DizzinessFAERS: 85US FAERS
4HeadacheFAERS: 74US FAERS
5TinnitusFAERS: 69US FAERS
6NauseaFAERS: 68US FAERS
7ParanoiaFAERS: 68US FAERS
8VertigoFAERS: 64US FAERS
9Feeling abnormalFAERS: 56US FAERS
10AmnesiaFAERS: 51US FAERS
11Memory impairmentFAERS: 42US FAERS
12Mood swingsFAERS: 41US FAERS
13Completed SuicideFAERS: 40US FAERS
14MalaiseFAERS: 39US FAERS
15TremorFAERS: 35US FAERS
16AgitationFAERS: 34US FAERS
17AstheniaFAERS: 33US FAERS
18AngerFAERS: 31US FAERS
19VomitingFAERS: 30US FAERS
20TachycardiaFAERS: 29US FAERS
21Weight decreasedFAERS: 29US FAERS
22DisorientationFAERS: 26US FAERS
23PalpitationsFAERS: 23US FAERS
24ChillsFAERS: 21US FAERS
25MyalgiaFAERS: 20US FAERS
26Night sweatsFAERS: 19US FAERS
27ArthralgiaFAERS: 18US FAERS
28Drug toxicityFAERS: 16US FAERS
29Drug exposure during pregnancyFAERS: 15US FAERS
30MalariaFAERS: 14US FAERS
31RestlessnessFAERS: 14US FAERS
32nervous system disorderFAERS: 14US FAERS
33Abdominal PainFAERS: 13US FAERS
34Emotional disorderFAERS: 13US FAERS
35HypersensitivityFAERS: 13US FAERS
36Impaired work abilityFAERS: 13US FAERS
37Suicide attemptFAERS: 13US FAERS
38Chest PainFAERS: 12US FAERS
39DyspepsiaFAERS: 12US FAERS
40PainFAERS: 12US FAERS
41Post-Traumatic Stress DisorderFAERS: 12US FAERS
42Visual disturbanceFAERS: 12US FAERS
43FormicationFAERS: 11US FAERS
44Visual ImpairmentFAERS: 11US FAERS
45Alanine Aminotransferase IncreasedFAERS: 10US FAERS
46Drug ineffectiveFAERS: 10US FAERS
47Irritable Bowel SyndromeFAERS: 10US FAERS
48NystagmusFAERS: 10US FAERS
49Panic DisorderFAERS: 10US FAERS
50PhotophobiaFAERS: 10US FAERS
51StressFAERS: 10US FAERS
52Atrial FibrillationFAERS: 9US FAERS
53Cold sweatFAERS: 9US FAERS
54DeafnessFAERS: 9US FAERS
55NervousnessFAERS: 9US FAERS
56Personality ChangeFAERS: 9US FAERS
57Physical assaultFAERS: 9US FAERS
58AgoraphobiaFAERS: 8US FAERS
59AphasiaFAERS: 8US FAERS
60Blood lactate dehydrogenase increasedFAERS: 8US FAERS
61CryingFAERS: 8US FAERS
62DehydrationFAERS: 8US FAERS
63Depressed moodFAERS: 8US FAERS
64ErythemaFAERS: 8US FAERS
65Toxicity to various agentsFAERS: 8US FAERS
66Unevaluable eventFAERS: 8US FAERS
67Activities of daily living impairedFAERS: 7US FAERS
68Adverse eventFAERS: 7US FAERS
69AnorexiaFAERS: 7US FAERS
70Blood creatine phosphokinase increasedFAERS: 7US FAERS
71ClaustrophobiaFAERS: 7US FAERS
72General physical health deteriorationFAERS: 7US FAERS
73HyperventilationFAERS: 7US FAERS
74Medication ErrorFAERS: 7US FAERS
75Motion SicknessFAERS: 7US FAERS
76MurderFAERS: 7US FAERS
77OverdoseFAERS: 7US FAERS
78Psychiatric symptomFAERS: 7US FAERS
79Abdominal discomfortFAERS: 6US FAERS
80Aspartate Aminotransferase IncreasedFAERS: 6US FAERS
81Back PainFAERS: 6US FAERS
82Chest discomfortFAERS: 6US FAERS
83DeliriumFAERS: 6US FAERS
84Gastrointestinal bacterial infectionFAERS: 6US FAERS
85HyperacusisFAERS: 6US FAERS
86HypothyroidismFAERS: 6US FAERS
87Myocardial InfarctionFAERS: 6US FAERS
88Neck PainFAERS: 6US FAERS
89Vestibular NeuronitisFAERS: 6US FAERS
90AcneFAERS: 5US FAERS
91AnhedoniaFAERS: 5US FAERS
92AtaxiaFAERS: 5US FAERS
93BronchospasmFAERS: 5US FAERS
94DiscomfortFAERS: 5US FAERS
95DissociationFAERS: 5US FAERS
96Emotional distressFAERS: 5US FAERS
97Impaired driving abilityFAERS: 5US FAERS
98LeukopeniaFAERS: 5US FAERS
99PancreatitisFAERS: 5US FAERS
100Product quality issueFAERS: 5US FAERS
101Respiratory FailureFAERS: 5US FAERS
102SomnolenceFAERS: 5US FAERS
103Urinary IncontinenceFAERS: 5US FAERS
104UrticariaFAERS: 5US FAERS
105Bipolar DisorderFAERS: 4US FAERS
106BlindnessFAERS: 4US FAERS
107Burning sensationFAERS: 4US FAERS
108ConstipationFAERS: 4US FAERS
109DysgeusiaFAERS: 4US FAERS
110Erectile dysfunctionFAERS: 4US FAERS
111Eye painFAERS: 4US FAERS
112HomicideFAERS: 4US FAERS
113IncoherentFAERS: 4US FAERS
114IncontinenceFAERS: 4US FAERS
115InflammationFAERS: 4US FAERS
116Joint swellingFAERS: 4US FAERS
117LethargyFAERS: 4US FAERS
118Pharyngolaryngeal PainFAERS: 4US FAERS
119Poor quality sleepFAERS: 4US FAERS
120Respiratory arrestFAERS: 4US FAERS
121Throat irritationFAERS: 4US FAERS
122ThrombocytopeniaFAERS: 4US FAERS
123White blood cell count decreasedFAERS: 4US FAERS
124Alcohol IntoleranceFAERS: 3US FAERS
125AlopeciaFAERS: 3US FAERS
126Amyotrophic Lateral SclerosisFAERS: 3US FAERS
127Anaphylactic shockFAERS: 3US FAERS
128ApathyFAERS: 3US FAERS
129Bipolar I disorderFAERS: 3US FAERS
130Blood thyroid stimulating hormone increasedFAERS: 3US FAERS
131CardiomegalyFAERS: 3US FAERS
132Economic problemFAERS: 3US FAERS
133EosinophiliaFAERS: 3US FAERS
134EpilepsyFAERS: 3US FAERS
135FibromyalgiaFAERS: 3US FAERS
136FlatulenceFAERS: 3US FAERS
137Gamma-Glutamyltransferase IncreasedFAERS: 3US FAERS
138GastroenteritisFAERS: 3US FAERS
139HypersomniaFAERS: 3US FAERS
140HypotensionFAERS: 3US FAERS
141Increased bronchial secretionFAERS: 3US FAERS
142Increased upper airway secretionFAERS: 3US FAERS
143InfectionFAERS: 3US FAERS
144Initial insomniaFAERS: 3US FAERS
145Intentional self-injuryFAERS: 3US FAERS
146Lichen PlanusFAERS: 3US FAERS
147Mental impairmentFAERS: 3US FAERS
148Middle insomniaFAERS: 3US FAERS
149Multiple allergiesFAERS: 3US FAERS
150MyocarditisFAERS: 3US FAERS
151Obsessive thoughtsFAERS: 3US FAERS
152Pharmaceutical product complaintFAERS: 3US FAERS
153PolyneuropathyFAERS: 3US FAERS
154PruritusFAERS: 3US FAERS
155Pulmonary FibrosisFAERS: 3US FAERS
156Status EpilepticusFAERS: 3US FAERS
157Umbilical malformationFAERS: 3US FAERS
158Unresponsive to stimuliFAERS: 3US FAERS
159AlveolitisFAERS: 2US FAERS
160AsthmaFAERS: 2US FAERS
161Autoimmune thyroiditisFAERS: 2US FAERS
162BradycardiaFAERS: 2US FAERS
163Brain stem syndromeFAERS: 2US FAERS
164CatatoniaFAERS: 2US FAERS
165Cerebral disorderFAERS: 2US FAERS
166Corneal ScarFAERS: 2US FAERS
167CyanosisFAERS: 2US FAERS
168DementiaFAERS: 2US FAERS
169Depressed Level of ConsciousnessFAERS: 2US FAERS
170DiplopiaFAERS: 2US FAERS
171DisabilityFAERS: 2US FAERS
172Dreamy stateFAERS: 2US FAERS
173Drug DependenceFAERS: 2US FAERS
174Drug prescribing errorFAERS: 2US FAERS
175Dry skinFAERS: 2US FAERS
176DysarthriaFAERS: 2US FAERS
177DysuriaFAERS: 2US FAERS
178Emotional povertyFAERS: 2US FAERS
179Eosinophilic PneumoniaFAERS: 2US FAERS
180EpicondylitisFAERS: 2US FAERS
181Euphoric moodFAERS: 2US FAERS
182Febrile infectionFAERS: 2US FAERS
183GastritisFAERS: 2US FAERS
184GlaucomaFAERS: 2US FAERS
185HostilityFAERS: 2US FAERS
186Hypereosinophilic syndromeFAERS: 2US FAERS
187Joint injuryFAERS: 2US FAERS
188Limb injuryFAERS: 2US FAERS
189LipomaFAERS: 2US FAERS
190Lymphocyte count increasedFAERS: 2US FAERS
191MicrocephalyFAERS: 2US FAERS
192MonoplegiaFAERS: 2US FAERS
193Negative thoughtsFAERS: 2US FAERS
194Nerve injuryFAERS: 2US FAERS
195PallorFAERS: 2US FAERS
196ParesisFAERS: 2US FAERS
197Plasmodium falciparum infectionFAERS: 2US FAERS
198PneumoniaFAERS: 2US FAERS
199PneumonitisFAERS: 2US FAERS
200ProteinuriaFAERS: 2US FAERS
201Renal painFAERS: 2US FAERS
202SarcoidosisFAERS: 2US FAERS
203Schizoaffective DisorderFAERS: 2US FAERS
204ScreamingFAERS: 2US FAERS
205Sensory integrative dysfunctionFAERS: 2US FAERS
206Sexual DysfunctionFAERS: 2US FAERS
207Simple Partial SeizuresFAERS: 2US FAERS
208SomnambulismFAERS: 2US FAERS
209Stevens-Johnson SyndromeFAERS: 2US FAERS
210Stress at workFAERS: 2US FAERS
211SyncopeFAERS: 2US FAERS
212TachyarrhythmiaFAERS: 2US FAERS
213TensionFAERS: 2US FAERS
214TheftFAERS: 2US FAERS
215Thermal burnFAERS: 2US FAERS
216TorticollisFAERS: 2US FAERS
217Trisomy 21FAERS: 2US FAERS
218UrethritisFAERS: 2US FAERS
219VasculitisFAERS: 2US FAERS
220Violence-related symptomFAERS: 2US FAERS
221Vitreous floatersFAERS: 2US FAERS
222AbasiaFAERS: 1US FAERS
223Acute respiratory failureFAERS: 1US FAERS
224Adjustment disorder with depressed moodFAERS: 1US FAERS
225AgeusiaFAERS: 1US FAERS
226Alanine aminotransferase abnormalFAERS: 1US FAERS
227Alcohol abuseFAERS: 1US FAERS
228Altered state of consciousnessFAERS: 1US FAERS
229Altered visual depth perceptionFAERS: 1US FAERS
230Angina PectorisFAERS: 1US FAERS
231AnhidrosisFAERS: 1US FAERS
232AnuriaFAERS: 1US FAERS
233Aortic RuptureFAERS: 1US FAERS
234Apparent deathFAERS: 1US FAERS
235ArthritisFAERS: 1US FAERS
236Arthropod biteFAERS: 1US FAERS
237AsthenopiaFAERS: 1US FAERS
238Atrioventricular BlockFAERS: 1US FAERS
239Auricular swellingFAERS: 1US FAERS
240Autonomic nervous system imbalanceFAERS: 1US FAERS
241Back disorderFAERS: 1US FAERS
242BedriddenFAERS: 1US FAERS
243Bipolar II disorderFAERS: 1US FAERS
244Bladder painFAERS: 1US FAERS
245Blood PressureFAERS: 1US FAERS
246Blood copper increasedFAERS: 1US FAERS
247Blood creatinine increasedFAERS: 1US FAERS
248Blood mercury abnormalFAERS: 1US FAERS
249Blood phosphorus decreasedFAERS: 1US FAERS
250Blood potassium decreasedFAERS: 1US FAERS
251Blood triglycerides increasedFAERS: 1US FAERS
252Body height above normalFAERS: 1US FAERS
253BronchitisFAERS: 1US FAERS
254BruxismFAERS: 1US FAERS
255CataplexyFAERS: 1US FAERS
256Cerebellar AtaxiaFAERS: 1US FAERS
257Cerebrovascular accidentFAERS: 1US FAERS
258Conversion disorderFAERS: 1US FAERS
259CoprolaliaFAERS: 1US FAERS
260Creatinine renal clearance increasedFAERS: 1US FAERS
261CystFAERS: 1US FAERS
262Cytolytic hepatitisFAERS: 1US FAERS
263Decompression SicknessFAERS: 1US FAERS
264Disease ProgressionFAERS: 1US FAERS
265Disease recurrenceFAERS: 1US FAERS
266Dissociative disorderFAERS: 1US FAERS
267Drug dispensing errorFAERS: 1US FAERS
268Drug dose omissionFAERS: 1US FAERS
269Drug level increasedFAERS: 1US FAERS
270DysgraphiaFAERS: 1US FAERS
271DysmorphismFAERS: 1US FAERS
272DystoniaFAERS: 1US FAERS
273Ear congestionFAERS: 1US FAERS
274Ear discomfortFAERS: 1US FAERS
275Ectopic PregnancyFAERS: 1US FAERS
276Educational problemFAERS: 1US FAERS
277EnuresisFAERS: 1US FAERS
278Exaggerated startle responseFAERS: 1US FAERS
279Executive dysfunctionFAERS: 1US FAERS
280Expired drug administeredFAERS: 1US FAERS
281Feeling ColdFAERS: 1US FAERS
282Feeling jitteryFAERS: 1US FAERS
283Feeling of body temperature changeFAERS: 1US FAERS
284Flank PainFAERS: 1US FAERS
285Flight of ideasFAERS: 1US FAERS
286Foaming at mouthFAERS: 1US FAERS
287Full blood count abnormalFAERS: 1US FAERS
288Gastrointestinal PainFAERS: 1US FAERS
289Hallucinations, mixedFAERS: 1US FAERS
290Head BangingFAERS: 1US FAERS
291Head discomfortFAERS: 1US FAERS
292HepatitisFAERS: 1US FAERS
293HepatomegalyFAERS: 1US FAERS
294Herpes dermatitisFAERS: 1US FAERS
295Histrionic Personality DisorderFAERS: 1US FAERS
296House dust allergyFAERS: 1US FAERS
297Human EhrlichiosisFAERS: 1US FAERS
298HypervigilanceFAERS: 1US FAERS
299Hypoaesthesia facialFAERS: 1US FAERS
300HypochondriasisFAERS: 1US FAERS
301HypokinesiaFAERS: 1US FAERS
302HyporeflexiaFAERS: 1US FAERS
303HypospadiasFAERS: 1US FAERS
304HypoxiaFAERS: 1US FAERS
305Imminent abortionFAERS: 1US FAERS
306ImmobileFAERS: 1US FAERS
307ImpetigoFAERS: 1US FAERS
308Incorrect dose administeredFAERS: 1US FAERS
309Incorrect drug administration durationFAERS: 1US FAERS
310Iron deficiencyFAERS: 1US FAERS
311Joint Range of Motion DecreasedFAERS: 1US FAERS
312LabyrinthitisFAERS: 1US FAERS
313Lactose IntoleranceFAERS: 1US FAERS
314Ligament painFAERS: 1US FAERS
315Loss of proprioceptionFAERS: 1US FAERS
316LymphadenitisFAERS: 1US FAERS
317Lymphocyte count abnormalFAERS: 1US FAERS
318Maternal exposure during pregnancyFAERS: 1US FAERS
319Mental RetardationFAERS: 1US FAERS
320Mental status changesFAERS: 1US FAERS
321MetamorphopsiaFAERS: 1US FAERS
322Mitochondrial toxicityFAERS: 1US FAERS
323Mood disorder due to a general medical conditionFAERS: 1US FAERS
324Morbid thoughtsFAERS: 1US FAERS
325Multiple SclerosisFAERS: 1US FAERS
326Muscle CrampFAERS: 1US FAERS
327Musculoskeletal PainFAERS: 1US FAERS
328MyoclonusFAERS: 1US FAERS
329NarcolepsyFAERS: 1US FAERS
330NasopharyngitisFAERS: 1US FAERS
331NephritisFAERS: 1US FAERS
332Nephrotic SyndromeFAERS: 1US FAERS
333NeuralgiaFAERS: 1US FAERS
334Neuralgic AmyotrophyFAERS: 1US FAERS
335Neurological decompensationFAERS: 1US FAERS
336Neurological examination abnormalFAERS: 1US FAERS
337NeuropathyFAERS: 1US FAERS
338Neuropsychiatric syndromeFAERS: 1US FAERS
339NeutropeniaFAERS: 1US FAERS
340Neutrophil count abnormalFAERS: 1US FAERS
341Neutrophil count decreasedFAERS: 1US FAERS
342Obsessive-Compulsive DisorderFAERS: 1US FAERS
343Optic AtrophyFAERS: 1US FAERS
344Oral administration complicationFAERS: 1US FAERS
345Oropharyngeal painFAERS: 1US FAERS
346Pericardial effusionFAERS: 1US FAERS
347Peripheral paralysisFAERS: 1US FAERS
348Physical abuseFAERS: 1US FAERS
349PiloerectionFAERS: 1US FAERS
350PlagiocephalyFAERS: 1US FAERS
351PoisoningFAERS: 1US FAERS
352Polymyalgia RheumaticaFAERS: 1US FAERS
353Poor quality drug administeredFAERS: 1US FAERS
354Postpartum stress disorderFAERS: 1US FAERS
355Pregnancy of partnerFAERS: 1US FAERS
356PregnancyFAERS: 1US FAERS
357Product contaminationFAERS: 1US FAERS
358PsoriasisFAERS: 1US FAERS
359Pulmonary EmbolismFAERS: 1US FAERS
360Pulmonary arterial hypertensionFAERS: 1US FAERS
361Pulmonary toxicityFAERS: 1US FAERS
362Quality of life decreasedFAERS: 1US FAERS
363Reflex Sympathetic DystrophyFAERS: 1US FAERS
364Respiratory DepressionFAERS: 1US FAERS
365Respiratory distressFAERS: 1US FAERS
366Restless Legs SyndromeFAERS: 1US FAERS
367RetchingFAERS: 1US FAERS
368RhabdomyolysisFAERS: 1US FAERS
369Rheumatoid ArthritisFAERS: 1US FAERS
370SchistosomiasisFAERS: 1US FAERS
371SchizophreniaFAERS: 1US FAERS
372Sexual abuseFAERS: 1US FAERS
373ShockFAERS: 1US FAERS
374Silent myocardial infarctionFAERS: 1US FAERS
375Sinoatrial BlockFAERS: 1US FAERS
376Sinus ArrhythmiaFAERS: 1US FAERS
377Sinus TachycardiaFAERS: 1US FAERS
378Sinus bradycardiaFAERS: 1US FAERS
379Skin discomfortFAERS: 1US FAERS
380Skin lesionFAERS: 1US FAERS
381Sleep disorder due to general medical condition, hypersomnia typeFAERS: 1US FAERS
382SoporFAERS: 1US FAERS
383Spinal column stenosisFAERS: 1US FAERS
384Supraventricular tachycardiaFAERS: 1US FAERS
385TalipesFAERS: 1US FAERS
386Temperature regulation disorderFAERS: 1US FAERS
387ThrombosisFAERS: 1US FAERS
388Tongue bitingFAERS: 1US FAERS
389UnderweightFAERS: 1US FAERS
390Vision abnormal neonatalFAERS: 1US FAERS
391Wheelchair userFAERS: 1US FAERS
392furuncleFAERS: 1US FAERS
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