MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Xanthomatosis

(UMLS:C0043325)

Definition:: A condition marked by the development of widespread xanthomas, yellow tumor-like structures filled with lipid deposits. Xanthomas can be found in a variety of tissues including the SKIN; TENDONS; joints of KNEES and ELBOWS. Xanthomatosis is associated with disturbance of LIPID METABOLISM and formation of FOAM CELLS.
UMLS ID:: C0043325
MeSH ID:: D014973

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.584.750

Synonym(s)

Xanthomatosis

XANTHOMATOSIS

Xanthomata

Xanthomatosis, NOS

Yellow bumps of fatty deposits on skin

xanthomatosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Ibuprofen	FAERS: 1		US FAERS
2	Minocycline	FAERS: 1		US FAERS
3	Ajmaline		5124256	CTD
4	Methyltestosterone		5124256	CTD
5	Norinyl		5124256	CTD
6	Ritonavir			SIDER
7	Sitosterols		11138003	CTD
8	acetiromate		4142437	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Dyslipidemias	46.7%
2	Lipodystrophy	33.3%
3	Lipomatosis	31.8%
4	Acid-Base Imbalance	31%
5	Calcium Metabolism Disorders	31%
6	Iron Metabolism Disorders	31%
7	Phosphorus Metabolism Disorders	31%
8	Water-Electrolyte Imbalance	31%
9	Mitochondrial Diseases	31%
10	Glucose Metabolism Disorders	31%
11	Hypercholesterolemia	28.5%
12	Hyperlipoproteinemias	28.5%
13	Hypertriglyceridemia	28.5%
14	Wasting Syndrome	27.9%
15	Hypercalcemia	26.7%
16	Hypocalcemia	26.7%
17	Milk-Alkali Syndrome	26.7%
18	Hyperlipoproteinemia Type IV	26%
19	Hyperlipoproteinemia Type V	26%
20	Hypolipoproteinemias	24.4%
21	Adiposis Dolorosa	23.1%
22	Hyperlipidemia, Familial Combined	21.5%
23	Osteopenia	20.9%
24	Brain Diseases, Metabolic	20.5%
25	Hypoalphalipoproteinemias	20.1%
26	Acidosis	20%
27	Alkalosis	20%
28	Amyloidosis	20%
29	Calcinosis	20%
30	Hyperglycemia	20%
31	Hyperinsulinism	20%
32	Hyperkalemia	20%
33	Hyperlipoproteinemia Type III	20%
34	Hypernatremia	20%
35	Hypoglycemia	20%
36	Hypokalemia	20%
37	Hyponatremia	20%
38	Hypophosphatemia	20%
39	Metabolic acidosis	20%
40	Iron Overload	20%
41	Nutrition Disorders	18.5%
42	Smith-Lemli-Opitz Syndrome	18.1%
43	Pseudohypoparathyroidism	18.1%
44	Rickets	17.3%
45	Brain Diseases, Metabolic, Inborn	15.9%
46	Neuronal Ceroid-Lipofuscinoses	15.5%
47	Leigh Disease	15.2%
48	Hyperhomocysteinemia	15.1%
49	Acidosis, Lactic	14.8%
50	Calciphylaxis	14.8%
51	Hemosiderosis	14.8%
52	Ketosis	14.8%
53	Ketonuria	14.8%
54	Ketoacidosis	14.8%
55	Ketonemia	14.8%
56	Vascular calcification	14.8%
57	Diabetes Mellitus	14.3%
58	Gaucher Disease	14.1%
59	HIV-Associated Lipodystrophy Syndrome	13.9%
60	Carbamoyl-Phosphate Synthase I Deficiency Disease	13.8%
61	Lactose Intolerance	13.7%
62	Dehydration	13.6%
63	Water Intoxication	13.6%
64	Werner Syndrome	13.6%
65	Diabetic Ketoacidosis	13.5%
66	Achlorhydria	13.3%
67	Amino Acid Metabolism, Inborn Errors	13.3%
68	Bloom Syndrome	13.3%
69	Carbohydrate Metabolism, Inborn Errors	13.3%
70	Metal Metabolism, Inborn Errors	13.3%
71	Osteoporosis	13.3%
72	Progeria	13.3%
73	Lysosomal Storage Diseases	13.3%
74	Bone Demineralization, Pathologic	13.3%
75	Cytochrome-c Oxidase Deficiency	13.3%
76	Peroxisomal Disorders	13.3%
77	Post-Traumatic Osteoporosis	13.3%
78	Celiac Disease	13.2%
79	Sprue, Tropical	13.2%
80	Steatorrhea	13.2%
81	Sprue	13.2%
82	Osteomalacia	13%
83	Tay-Sachs Disease	12.5%
84	Galactosemias	12.5%
85	Urea Cycle Disorders, Inborn	12.5%
86	Tyrosinemias	12.5%
87	Congenital Hyperinsulinism	12.2%
88	Niemann-Pick Disease, Type C	11.8%
89	Familial Hypophosphatemic Rickets	11.5%
90	Mitochondrial Encephalomyopathies	11.5%
91	Hyperphosphaturia	10.9%
92	Fabry Disease	10.9%
93	Glycogen storage disease type II	10.6%
94	Homocystinuria	10.4%
95	Child Nutrition Disorders	10.3%
96	Hypervitaminosis A	10.3%
97	Infant Nutrition Disorders	10.3%
98	Malnutrition	10.3%
99	Mitochondrial Myopathies	10.2%
100	Myelinolysis, Central Pontine	10.1%
101	Glycosuria	9.9%
102	Reye Syndrome	9.9%
103	Acidosis, Respiratory	9.9%
104	Alkalosis, Respiratory	9.9%
105	Hepatic Encephalopathy	9.8%
106	Nesidioblastosis	9.8%
107	Alkaptonuria	9.8%
108	Glycogen Storage Disease	9.8%
109	Hypophosphatasia	9.8%
110	Insulin Resistance	9.8%
111	Osteoporosis, Postmenopausal	9.8%
112	Propionic acidemia	9.8%
113	Dihydropyrimidine Dehydrogenase Deficiency	9.8%
114	Cystinosis	9.8%
115	Amyloid Neuropathies, Familial	9.8%
116	Renal tubular acidosis	9.7%
117	Sjogren-Larsson Syndrome	9.3%
118	HIV Wasting Syndrome	8.8%
119	MELAS Syndrome	8.2%
120	Renal Osteodystrophy	8.2%
121	Renal rickets	8.2%
122	Porphyrias, Hepatic	8.1%
123	Glycogen Storage Disease Type I	8.1%
124	Glycogen Storage Disease Type V	8.1%
125	Zellweger Syndrome	8%
126	Mucopolysaccharidosis III	8%
127	Adrenoleukodystrophy	8%
128	Necrobiosis Lipoidica Diabeticorum	7.9%
129	Menkes Kinky Hair Syndrome	7.9%
130	Fanconi Anemia	7.8%
131	Wernicke Encephalopathy	7.7%
132	Gestational Diabetes	7.7%
133	Latent Autoimmune Diabetes in Adults	7.7%
134	Diabetes Mellitus, Experimental	7.6%
135	Hepatolenticular Degeneration	7.4%
136	Nephrocalcinosis	7.4%
137	Tetany	7.4%
138	Refsum Disease	7.3%
139	Glycosuria, Renal	7.3%
140	Cerebral Amyloid Angiopathy	7.2%
141	Deficiency Diseases	6.7%
142	Starvation	6.7%
143	Refeeding Syndrome	6.7%
144	Friedreich Ataxia	6.5%
145	Familial Periodic Paralysis	6%
146	Primary amyloidosis	6%
147	Variegate Porphyria	5.9%
148	Acute intermittent porphyria	5.9%
149	Porphyria Cutanea Tarda	5.9%
150	Renal Aminoacidurias	5.8%
151	Fanconi Syndrome	5.8%
152	Pseudohypoaldosteronism	5.8%
153	Liddle Syndrome	5.8%
154	Kernicterus	5.7%
155	Kearns-Sayre syndrome	5.7%
156	Cockayne Syndrome	5.7%
157	Canavan Disease	5.4%
158	Alexander Disease	5.4%
159	Mucopolysaccharidosis II	5.3%
160	Ataxia Telangiectasia	5.1%
161	Gout	5%
162	Amyotrophic Lateral Sclerosis	5%
163	Kwashiorkor	4.9%
164	Magnesium Deficiency	4.9%
165	Potassium Deficiency	4.9%
166	Protein Deficiency	4.9%
167	Avitaminosis	4.9%
168	Optic Atrophy, Hereditary, Leber	4.9%
169	Antley-Bixler Syndrome Phenotype	4.9%
170	Hypokalemic periodic paralysis	4.9%
171	Frontotemporal dementia	4.8%
172	Cystinuria	4.8%
173	Xeroderma Pigmentosum	4.5%
174	CREST Syndrome	4.2%
175	Ascorbic Acid Deficiency	4.1%
176	Vitamin A Deficiency	4.1%
177	Vitamin D Deficiency	4.1%
178	Vitamin E Deficiency	4.1%
179	Marasmus	4.1%
180	Arthritis, Gouty	4.1%
181	Albinism	3.7%
182	Folic Acid Deficiency	3.6%
183	Pellagra	3.6%
184	Thiamine Deficiency	3.6%
185	Vitamin B 12 Deficiency	3.6%
186	Vitamin B 6 Deficiency	3.6%
187	Pyridoxine Deficiency	3.6%
188	Beriberi	3.4%
189	Ichthyosis, X-Linked	3%
190	Obesity	2.6%
191	Obesity, Abdominal	2.4%
192	Anemia, Pernicious	2.3%
193	Vitamin K Deficiency	2.1%
194	Pediatric Obesity	1.9%
195	Scurvy	1.8%
196	Prader-Willi Syndrome	1.6%
197	Subacute Combined Degeneration	1.2%

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