MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Wiskott-Aldrich Syndrome

(UMLS:C0043194)

Definition:: A rare, X-linked immunodeficiency syndrome characterized by ECZEMA; LYMPHOPENIA; and, recurrent pyogenic infection. It is seen exclusively in young boys. Typically, IMMUNOGLOBULIN M levels are low and IMMUNOGLOBULIN A and IMMUNOGLOBULIN E levels are elevated. Lymphoreticular malignancies are common.
UMLS ID:: C0043194
MeSH ID:: D014923

Classification 1:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.378.100.100.970|C15.378.463.960|C15.378.553.546.605.900

Classification 2:

Name:

Congenital, Hereditary, and Neonatal Diseases and Abnormalities
MeSH Tree Number(s):: C16.320.099.970|C16.320.322.937

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.673.627.900

Synonym(s)

Wiskott-Aldrich Syndrome

ALDRICH SYNDROME

Aldrich

Aldrich syndrome

Eczema, thrombocytopenia, immunodeficiency syndrome

IMMUNODEFICIENCY WITH ECZEMA AND THROMBOCYTOPENIA

Immunodeficiency with thrombocytopenia AND eczema

Immunodeficiency with thrombocytopenia and eczema

WAS - Wiskott-Aldrich syndrome

10.

WISKOTT-ALDRICH SYNDROME

11.

Wiskott Aldrich Syndrome

12.

Wiskott Aldrich syndrome

13.

Wiskott-Aldrich

14.

Wiskott-Aldrich syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Megestrol Acetate	FAERS: 1		US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Thrombasthenia	51.6%
2	Afibrinogenemia	51.1%
3	Factor VII Deficiency	51.1%
4	Factor X Deficiency	51.1%
5	Factor XII Deficiency	51.1%
6	Hemophilia A	51.1%
7	Factor II deficiency	51.1%
8	Factor VIII Deficiency	51.1%
9	Factor V deficiency	51.1%
10	Factor XI Deficiency	51.1%
11	Hypoprothrombinemias	51.1%
12	Antithrombin III Deficiency	46.3%
13	Protein C Deficiency	46.3%
14	Activated Protein C Resistance	45.8%
15	Disseminated Intravascular Coagulation	41.7%
16	Thrombocythemia, Essential	39.2%
17	Protein S Deficiency	35.8%
18	Vitamin K Deficiency	31%
19	Pelger-Huet Anomaly	31%
20	Anemia, Sickle Cell	30.1%
21	Thalassemia	30.1%
22	Chronic granulomatous disease	28.3%
23	Transfusion Reaction	24.1%
24	Hypotensive Transfusion Reaction	24.1%
25	Anemia, Diamond-Blackfan	24%
26	Autoimmune thrombocytopenia	22.9%
27	Immune thrombocytopenic purpura	22.9%
28	Aicardi's syndrome	22.8%
29	Sickle Cell Trait	22.2%
30	Anemia	22.1%
31	Blood Platelet Disorders	22.1%
32	Bone Marrow Diseases	22.1%
33	Methemoglobinemia	22.1%
34	Pancytopenia	22.1%
35	Polycythemia	22.1%
36	Sulfhemoglobinemia	22.1%
37	Thrombophilia	22.1%
38	Erythrocytosis	22.1%
39	Fragile X Syndrome	21.3%
40	Muscular Dystrophy, Duchenne	21%
41	Ichthyosis, X-Linked	21%
42	Bone Marrow Neoplasms	20.9%
43	Agammaglobulinemia	20.7%
44	Thrombocytosis	19.7%
45	Pregnancy Complications, Hematologic	19.5%
46	Hematologic Neoplasms	19.5%
47	Polycythemia Vera	19.1%
48	Acute Chest Syndrome	18.8%
49	Autoimmune Lymphoproliferative Syndrome	18.6%
50	Leukemoid Reaction	18.4%
51	Hydrops Fetalis	18.4%
52	Purpura, Thrombotic Thrombocytopenic	18.4%
53	Eosinophilia	18.1%
54	Leukostasis	18.1%
55	Wiskott-Aldrich Syndrome	18.1%
56	Cryoglobulinemia	18.1%
57	Mucopolysaccharidosis II	18%
58	Waldenstrom Macroglobulinemia	17.7%
59	Fanconi Anemia	17.7%
60	Agranulocytosis	17.6%
61	Purpura, Hyperglobulinemic	17.5%
62	Rett Syndrome	17.4%
63	Infectious Mononucleosis	17.1%
64	Menkes Kinky Hair Syndrome	17.1%
65	Anemia, Neonatal	16.8%
66	Albinism	16.8%
67	Cystic Fibrosis	16.3%
68	CHARGE Syndrome	16.3%
69	Pseudoxanthoma Elasticum	16.2%
70	Multiple Myeloma	16.2%
71	Leukocytosis	16%
72	Pleocytosis	16%
73	Hemoglobinuria, Paroxysmal	16%
74	Thrombocytopenic purpura	15.9%
75	Alstrom Syndrome	15.7%
76	Leukocyte Disorders	15.7%
77	Waterhouse-Friderichsen Syndrome	15.6%
78	Monoclonal Gammopathy of Undetermined Significance	15.4%
79	Cockayne Syndrome	15.4%
80	Job Syndrome	15.4%
81	Neoplastic Syndromes, Hereditary	15.4%
82	Multiple Epiphyseal Dysplasia	15%
83	Osteochondrodysplasias	15%
84	Werner Syndrome	15%
85	Myasthenic Syndromes, Congenital	15%
86	Blood Coagulation Disorders	15%
87	Ecchymosis	14.9%
88	Petechiae	14.9%
89	Purpura	14.9%
90	Nail-Patella Syndrome	14.7%
91	Beckwith-Wiedemann Syndrome	14.7%
92	Wolf-Hirschhorn Syndrome	14.7%
93	Adrenoleukodystrophy	14.6%
94	Kartagener Syndrome	14.4%
95	Fabry Disease	14.4%
96	Paraproteinemias	14.3%
97	Ataxia Telangiectasia	13.8%
98	Dwarfism	13.6%
99	Hemorrhagic Disorders	13.5%
100	Anemia, Hemolytic	13.4%
101	Anemia, Macrocytic	13.4%
102	Hypoproteinemia	13.4%
103	Thrombocytopenia	13.4%
104	MYELODYSPLASTIC SYNDROME	13.4%
105	Lymphatic Diseases	13.3%
106	Smith-Magenis syndrome	13.3%
107	Muscular Dystrophy	13.3%
108	Osteogenesis Imperfecta	13.3%
109	Holoprosencephaly	13.2%
110	Cri-du-Chat Syndrome	13.2%
111	Down Syndrome	13.2%
112	Trisomy 21	13.2%
113	Hypergammaglobulinemia	12.8%
114	Marfan Syndrome	12.8%
115	Transfusion-Related Acute Lung Injury	12.7%
116	Angioedemas, Hereditary	12.7%
117	Neutropenia	12.6%
118	Myotonic Dystrophy	12.1%
119	Heavy Chain Disease	12.1%
120	Ectodermal Dysplasia	12%
121	Aplasia Cutis Congenita	12%
122	Smith-Lemli-Opitz Syndrome	12%
123	Prader-Willi Syndrome	12%
124	Lymphocytosis	11.9%
125	Hypereosinophilic syndrome	11.9%
126	Tuberous Sclerosis	11.9%
127	Kernicterus	11.8%
128	Classical Lissencephalies and Subcortical Band Heterotopias	11.6%
129	Rubinstein-Taybi Syndrome	11.6%
130	Neuronal Ceroid-Lipofuscinoses	11.6%
131	Hepatolenticular Degeneration	11.6%
132	Sjogren-Larsson Syndrome	11.5%
133	Lymphatic Abnormalities	11.5%
134	Shwartzman Phenomenon	11.5%
135	Hemangioma, Cavernous	11.5%
136	Refsum Disease	11.5%
137	Scurvy	11.4%
138	Familial Mediterranean Fever	11.3%
139	Hemolytic-Uremic Syndrome	11.2%
140	Kallmann Syndrome	11.2%
141	Amyloid Neuropathies, Familial	10.5%
142	Polycystic Kidney Diseases	10.5%
143	Williams Syndrome	10.5%
144	Glycogen storage disease type II	10.4%
145	POEMS Syndrome	10.3%
146	Primary Ciliary Dyskinesia	10.3%
147	Febrile Neutropenia	10.2%
148	Purpura Fulminans	10%
149	Lymphangiectasis, Intestinal	9.9%
150	Amino Acid Metabolism, Inborn Errors	9.9%
151	Carbohydrate Metabolism, Inborn Errors	9.9%
152	Metal Metabolism, Inborn Errors	9.9%
153	Progeria	9.9%
154	Lysosomal Storage Diseases	9.9%
155	Cytochrome-c Oxidase Deficiency	9.9%
156	Peroxisomal Disorders	9.9%
157	Leukopenia	9.9%
158	Retinal Dysplasia	9.8%
159	Galactosemias	9.8%
160	Urea Cycle Disorders, Inborn	9.8%
161	Tyrosinemias	9.8%
162	Aniridia	9.7%
163	Deformity	9.7%
164	Epidermolysis Bullosa	9.6%
165	Eosinophilic Granuloma	9.6%
166	Eosinophilia-Myalgia Syndrome	9.4%
167	Primary Myelofibrosis	9.1%
168	Anemia, Megaloblastic	9.1%
169	Myelofibrosis	9.1%
170	Myeloid Metaplasia	9.1%
171	Hypoalbuminemia	9.1%
172	bone marrow fibrosis	9.1%
173	Thrombotic Microangiopathies	9.1%
174	Canavan Disease	9.1%
175	Alexander Disease	9.1%
176	Optic Atrophy, Hereditary, Leber	9%
177	Zellweger Syndrome	9%
178	Lymphoproliferative Disorders	9%
179	Hyperphosphaturia	9%
180	Atypical Hemolytic Uremic Syndrome	9%
181	Cutis Laxa	8.9%
182	Retinitis Pigmentosa	8.8%
183	Pigmentary retinopathy	8.8%
184	Mucopolysaccharidosis III	8.8%
185	Porokeratosis	8.8%
186	Keratoderma, Palmoplantar	8.8%
187	Welander Distal Myopathy	8.7%
188	Gaucher Disease	8.7%
189	Niemann-Pick Disease, Type C	8.6%
190	Fetal Diseases	8.5%
191	Dermatitis, Atopic	8.4%
192	Homocystinuria	8.3%
193	Leigh Disease	8.3%
194	Duane Retraction Syndrome	8%
195	Porphyrias, Hepatic	8%
196	Leukemia, Myelomonocytic, Chronic	8%
197	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	8%
198	Peutz-Jeghers Syndrome	7.9%
199	Myotonia Congenita	7.9%
200	Brain Diseases, Metabolic, Inborn	7.9%
201	Tay-Sachs Disease	7.9%
202	Dystonia Musculorum Deformans	7.9%
203	Pulmonary Eosinophilia	7.9%
204	Eosinophilic Pneumonia	7.9%
205	Hyperkeratosis, Epidermolytic	7.8%
206	Lafora Disease	7.8%
207	Unverricht-Lundborg Syndrome	7.8%
208	Polycystic Kidney, Autosomal Dominant	7.8%
209	Xeroderma Pigmentosum	7.6%
210	Carbamoyl-Phosphate Synthase I Deficiency Disease	7.5%
211	Adenitis	7.4%
212	Histiocytosis	7.4%
213	Lymphadenitis	7.4%
214	Lymphangitis	7.4%
215	Lymphedema	7.4%
216	Splenic Diseases	7.4%
217	Thymus Hyperplasia	7.4%
218	Pseudolymphoma	7.4%
219	Lymphadenopathy	7.4%
220	Alkaptonuria	7.4%
221	Glycogen Storage Disease	7.4%
222	Hypophosphatasia	7.4%
223	Propionic acidemia	7.4%
224	Dihydropyrimidine Dehydrogenase Deficiency	7.4%
225	Cystinosis	7.4%
226	Meconium Aspiration Syndrome	7.4%
227	Multiple Endocrine Neoplasia	7.4%
228	Congenital Hypothyroidism	7.2%
229	Charcot-Marie-Tooth Disease	7.1%
230	Antley-Bixler Syndrome Phenotype	7.1%
231	Basal Cell Nevus Syndrome	7%
232	Xeroderma	6.7%
233	Mobius Syndrome	6.7%
234	HIV Infections	6.6%
235	Behcet Syndrome	6.6%
236	Hypolipoproteinemias	6.5%
237	Papillon-Lefevre Disease	6.5%
238	Hyperlipidemia, Familial Combined	6.5%
239	Hyperlipoproteinemia Type III	6.5%
240	Lymphocele	6.5%
241	Thymus Neoplasms	6.4%
242	Klinefelter Syndrome	6.2%
243	Lymphopenia	6.2%
244	Turner Syndrome	6.1%
245	Glycogen Storage Disease Type I	6.1%
246	Glycogen Storage Disease Type V	6.1%
247	Leukemia, Myeloid, Chronic-Phase	6.1%
248	Anemia, Pernicious	6.1%
249	Huntington Disease	6.1%
250	Familial Periodic Paralysis	6%
251	Lactose Intolerance	5.9%
252	Variegate Porphyria	5.9%
253	Acute intermittent porphyria	5.9%
254	Porphyria Cutanea Tarda	5.9%
255	Hyperhomocysteinemia	5.9%
256	Renal Aminoacidurias	5.9%
257	Fanconi Syndrome	5.9%
258	Pseudohypoaldosteronism	5.9%
259	Liddle Syndrome	5.9%
260	Hyperlipoproteinemia Type IV	5.8%
261	Hyperlipoproteinemia Type V	5.8%
262	Sezary Syndrome	5.8%
263	Mucocutaneous Lymph Node Syndrome	5.7%
264	Abdominal Cramps	5.7%
265	Abnormalities, Drug-Induced	5.7%
266	Amniotic Band Syndrome	5.7%
267	Asphyxia Neonatorum	5.7%
268	Infant, Premature, Diseases	5.7%
269	Situs Inversus	5.7%
270	Infantile Colic	5.7%
271	Nephroblastoma	5.6%
272	Tumor Lysis Syndrome	5.6%
273	Hypoalphalipoproteinemias	5.4%
274	Gout	5.4%
275	Multiple Endocrine Neoplasia Type 1	5.4%
276	Pseudohypoparathyroidism	5.4%
277	Familial Hypophosphatemic Rickets	5.3%
278	Friedreich Ataxia	5.3%
279	Renal tubular acidosis	5.3%
280	Adenomatous Polyposis Coli	5.2%
281	Anencephaly	5.1%
282	Eye Abnormalities	5.1%
283	Cardiovascular Abnormalities	5.1%
284	Skin Abnormalities	5%
285	Congenital Microtia	5%
286	Lymphoma	5%
287	Persistent Fetal Circulation Syndrome	5%
288	Congenital diaphragmatic hernia	5%
289	Umbilical hernia	5%
290	HTLV-I Infections	4.9%
291	Hypokalemic periodic paralysis	4.9%
292	Cystinuria	4.9%
293	Autoimmune Diseases	4.8%
294	Hypersensitivity	4.8%
295	Immunoproliferative Disorders	4.8%
296	Immune reconstitution syndrome	4.8%
297	Immune Reconstitution Inflammatory Syndrome	4.8%
298	Maxillofacial Abnormalities	4.6%
299	Dural Arteriovenous Fistula	4.6%
300	Dextrocardia	4.6%
301	Urogenital Abnormalities	4.6%
302	Neonatal Abstinence Syndrome	4.5%
303	Glycosuria, Renal	4.5%
304	Elephantiasis	4.5%
305	Hypersplenism	4.5%
306	Sarcoidosis	4.5%
307	Elephantiasis Nostras Verrucosa	4.5%
308	Arthritis, Gouty	4.4%
309	Fetal Growth Retardation	4.4%
310	Fetal Hypoxia	4.4%
311	Congenital nystagmus	4.4%
312	Fetal Alcohol Spectrum Disorders	4.4%
313	Toxoplasmosis, Congenital	4.4%
314	Syphilis, Congenital	4.4%
315	HIV Seropositivity	4.4%
316	Denys-Drash Syndrome	4.1%
317	Acrocephalosyndactylia	4%
318	Congenital Hyperinsulinism	4%
319	Chorioamnionitis	4%
320	Acquired Immunodeficiency Syndrome	4%
321	AIDS related complex	4%
322	Granuloma	4%
323	Histiocytic Disorders, Malignant	4%
324	Splenic Infarction	4%
325	Splenic Neoplasms	4%
326	Histiocytosis, Langerhans-Cell	3.9%
327	Scimitar Syndrome	3.9%
328	MELAS Syndrome	3.9%
329	Prune Belly Syndrome	3.8%
330	Twins, Conjoined	3.8%
331	Waardenburg Syndrome	3.8%
332	Glomerulonephritis, Membranoproliferative	3.7%
333	AIDS-Related Opportunistic Infections	3.6%
334	Abnormalities, Radiation-Induced	3.6%
335	Microcephaly	3.6%
336	Macrocephaly	3.6%
337	HIV Wasting Syndrome	3.6%
338	AIDS Dementia Complex	3.6%
339	Craniosynostosis	3.6%
340	Syndactyly	3.6%
341	AIDS-Associated Nephropathy	3.6%
342	Brachycephaly	3.6%
343	Splenic Rupture	3.5%
344	Thymoma	3.5%
345	Hodgkin Disease	3.5%
346	Lymphoma, Non-Hodgkin	3.5%
347	Leukemia, T-Cell	3.4%
348	Leukemia, B-Cell	3.4%
349	Cleft Palate	3.4%
350	Anophthalmos	3.3%
351	Anus, Imperforate	3.3%
352	Hydranencephaly	3.3%
353	Microphthalmos	3.3%
354	Neural Tube Defects	3.3%
355	Paralysis, Obstetric	3.3%
356	Retinopathy of Prematurity	3.3%
357	Tethered Cord Syndrome	3.3%
358	Iniencephaly	3.3%
359	Craniorachischisis	3.3%
360	Limb Deformities, Congenital	3.3%
361	Exencephaly	3.3%
362	Septo-Optic Dysplasia	3.3%
363	Craniofacial Abnormalities	3.3%
364	Cortical Dysplasia	3.3%
365	Malformations of Cortical Development	3.3%
366	Anorectal Malformations	3.3%
367	Noonan Syndrome	3.3%
368	Bloom Syndrome	3.3%
369	Bronchopulmonary Dysplasia	3.3%
370	Ophthalmia Neonatorum	3.3%
371	HIV-Associated Lipodystrophy Syndrome	3.3%
372	Porencephaly	3.3%
373	Composite Lymphoma	3.1%
374	Lymphangioleiomyomatosis	3.1%
375	Lymphohistiocytosis, Hemophagocytic	3%
376	Erdheim-Chester Disease	3%
377	Jaw Abnormalities	3%
378	Blepharophimosis	3%
379	Laryngostenosis	3%
380	Mouth Abnormalities	3%
381	Respiratory Distress Syndrome, Newborn	3%
382	Esophageal Atresia	3%
383	Intestinal Atresia	3%
384	Horseshoe Kidney	3%
385	Pectus excavatum	3%
386	Poland Syndrome	2.9%
387	Klippel-Feil Syndrome	2.9%
388	Gastroschisis	2.9%
389	Synostosis	2.9%
390	Acrodermatitis	2.9%
391	Gianotti-Crosti Syndrome	2.9%
392	Immune Complex Diseases	2.9%
393	Antiphospholipid Syndrome	2.9%
394	Latex allergy	2.9%
395	Lymphoma, Follicular	2.7%
396	T-Cell Lymphoma	2.7%
397	Mantle cell lymphoma	2.7%
398	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2.7%
399	Leukemia, Large Granular Lymphocytic	2.7%
400	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2.7%
401	Arthrogryposis	2.7%
402	Choanal Atresia	2.7%
403	Tracheobronchomegaly	2.7%
404	Laryngocele	2.7%
405	Choledochal Cyst	2.7%
406	Hermaphroditism	2.7%
407	Disorders of Sex Development	2.7%
408	Malignant histiocytosis	2.7%
409	Sarcoidosis, Pulmonary	2.7%
410	Histiocytic sarcoma	2.7%
411	Cryptorchidism	2.7%
412	Hypospadias	2.7%
413	Central Nervous System Cysts	2.7%
414	Dandy-Walker Syndrome	2.6%
415	Primary amyloidosis	2.6%
416	Leukomalacia, Periventricular	2.6%
417	Nesidioblastosis	2.6%
418	Micrognathism	2.6%
419	Pierre Robin Syndrome	2.6%
420	Environmental Illness	2.6%
421	Lupus Erythematosus, Systemic	2.5%
422	Overlap syndrome	2.5%
423	Addison Disease	2.5%
424	Pemphigus	2.5%
425	Autoimmune thyroiditis	2.5%
426	Primary Adrenal Insufficiency	2.5%
427	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.5%
428	Autoimmune hepatitis	2.5%
429	Amelia	2.5%
430	Arachnodactyly	2.5%
431	Ectopia Cordis	2.5%
432	Ectromelia	2.5%
433	Hemimelia	2.5%
434	Meningomyelocele	2.5%
435	Phocomelia	2.5%
436	Sirenomelia	2.5%
437	Spina Bifida	2.5%
438	Polydactyly	2.5%
439	Brachydactyly	2.5%
440	Plagiocephaly	2.5%
441	Lower Extremity Deformities, Congenital	2.5%
442	Upper Extremity Deformities, Congenital	2.5%
443	Single umbilical artery	2.5%
444	Laryngomalacia	2.5%
445	Pectus carinatum	2.4%
446	Bladder Exstrophy	2.4%
447	Epispadias	2.4%
448	Asthma, Aspirin-Induced	2.4%
449	Multicystic Dysplastic Kidney	2.4%
450	Retrognathia	2.4%
451	Splenosis	2.4%
452	Lymphoma, T-Cell, Cutaneous	2.3%
453	Lymphoma, AIDS-Related	2.3%
454	Enteropathy-Associated T-Cell Lymphoma	2.3%
455	Primary Effusion Lymphoma	2.3%
456	Hyperandrogenism	2.3%
457	Serum Sickness	2.3%
458	Latent Autoimmune Diabetes in Adults	2.2%
459	Prognathism	2.2%
460	Dermatitis Herpetiformis	2.2%
461	Kounis Syndrome	2.2%
462	Aortic coarctation	2.2%
463	Cor Triatriatum	2.2%
464	Coronary Vessel Anomalies	2.2%
465	Dental Enamel Hypoplasia	2.2%
466	Patent ductus arteriosus	2.2%
467	Ebstein Anomaly	2.2%
468	Heart Septal Defects	2.2%
469	Hyaline Membrane Disease	2.2%
470	Hypodontia	2.2%
471	Macrostomia	2.2%
472	Meningocele	2.2%
473	Microstomia	2.2%
474	Tetralogy of Fallot	2.2%
475	Transposition of Great Vessels	2.2%
476	Hypoplastic Left Heart Syndrome	2.2%
477	May-Thurner Syndrome	2.2%
478	Encephalocele	2.2%
479	Craniofacial Dysostosis	2.2%
480	Wolff-Parkinson-White Syndrome	2.2%
481	Mycosis Fungoides	2.2%
482	Lymphomatoid Papulosis	2.2%
483	Plasmablastic lymphoma	2.2%
484	Lymphomatoid Granulomatosis	2.1%
485	Dermal Sinus	2%
486	Spina Bifida Cystica	2%
487	Spina Bifida Occulta	2%
488	Lissencephaly	2%
489	Polymicrogyria	2%
490	Pachygyria	2%
491	Schizencephaly	2%
492	Periventricular Nodular Heterotopia	2%
493	Rheumatoid Arthritis	2%
494	Juvenile arthritis	2%
495	Graves Disease	2%
496	Long QT Syndrome	2%
497	Platybasia	2%
498	Tricuspid Atresia	2%
499	Arrhythmogenic Right Ventricular Dysplasia	2%
500	Anti-Glomerular Basement Membrane Disease	2%
501	Gonadal Dysgenesis	2%
502	Bronchomalacia	2%
503	Adrenogenital Syndrome	2%
504	Tracheomalacia	2%
505	Ovotesticular Disorders of Sex Development	2%
506	Burkitt Lymphoma	1.9%
507	anaphylaxis	1.9%
508	Food Allergy	1.9%
509	Anaphylactic shock	1.9%
510	Aortopulmonary Septal Defect	1.8%
511	Double Outlet Right Ventricle	1.8%
512	Endocardial Cushion Defects	1.8%
513	Myocardial bridging	1.8%
514	Aorticopulmonary Septal Defect	1.8%
515	Respiratory Hypersensitivity	1.7%
516	Sick Building Syndrome	1.7%
517	Multiple Chemical Sensitivity	1.7%
518	Plasmacytoma	1.6%
519	Urticaria	1.6%
520	Vasculitis, Leukocytoclastic, Cutaneous	1.6%
521	Myasthenia Gravis, Autoimmune, Experimental	1.6%
522	Mandibulofacial Dysostosis	1.6%
523	Romano-Ward Syndrome	1.6%
524	Truncus Arteriosus, Persistent	1.6%
525	Goldenhar Syndrome	1.6%
526	Myasthenia Gravis	1.5%
527	Uveomeningoencephalitic Syndrome	1.5%
528	Mastocytosis	1.5%
529	Talipes	1.5%
530	Drug Eruptions	1.5%
531	Granulomatosis with polyangiitis	1.5%
532	Dermatitis, Allergic Contact	1.5%
533	Milk Allergy	1.4%
534	Schnitzler Syndrome	1.4%
535	Wheat Hypersensitivity	1.4%
536	Congenital clubfoot	1.4%
537	Vertical Talus	1.4%
538	Arteriovenous fistula	1.4%
539	Lupus Vasculitis, Central Nervous System	1.3%
540	Stiff-Person Syndrome	1.3%
541	Polyradiculoneuropathy	1.3%
542	Polyradiculoneuritis	1.3%
543	Felty Syndrome	1.3%
544	Lupus Nephritis	1.3%
545	Neuromyelitis Optica	1.3%
546	Leukoencephalitis, Acute Hemorrhagic	1.3%
547	Mastocytosis, Systemic	1.2%
548	Vasculitis, Central Nervous System	1.2%
549	Rheumatoid Vasculitis	1.2%
550	Lambert-Eaton Myasthenic Syndrome	1.1%
551	Angioedema	1.1%
552	Multiple Sclerosis	1.1%
553	Sicca Syndrome	1.1%
554	Sjogren's Syndrome	1.1%
555	Leukemia, Plasma Cell	1.1%
556	Acute Generalized Exanthematous Pustulosis	1.1%
557	Asthma	1%
558	Encephalomyelitis, Acute Disseminated	1%
559	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	1%
560	Erythema Nodosum	1%
561	Neuritis, Autoimmune, Experimental	1%
562	Dermatitis, Photoallergic	1%
563	Asthma, Exercise-Induced	0.9%
564	Status Asthmaticus	0.9%
565	Multiple Sclerosis, Chronic Progressive	0.9%
566	Multiple Sclerosis, Relapsing-Remitting	0.9%
567	Aspergillosis, Allergic Bronchopulmonary	0.9%
568	Guillain-Barre Syndrome	0.9%
569	Asthma, Occupational	0.8%
570	Farmer's Lung	0.8%
571	Hay fever	0.8%
572	Rhinitis, Allergic, Perennial	0.8%
573	Toxic Epidermal Necrolysis	0.8%
574	Stevens-Johnson Syndrome	0.8%
575	Hereditary Angioedema Type III	0.8%
576	Hereditary Angioedema Types I and II	0.8%
577	Giant Cell Arteritis	0.8%
578	Temporal Arteritis	0.8%
579	Myelitis, Transverse	0.7%
580	Miller Fisher Syndrome	0.6%

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