MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Fatty Liver, Alcoholic

(UMLS:C0015696)

Definition:: Lipid infiltration of the hepatic parenchymal cells that is due to ALCOHOL ABUSE. The fatty changes in the alcoholic fatty liver may be reversible, depending on the amounts of TRIGLYCERIDES accumulated.
UMLS ID:: C0015696
MeSH ID:: D005235

Classification 1:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.552.241.390|C06.552.645.390

Classification 2:

Name:

Chemically-Induced Disorders
MeSH Tree Number(s):: C25.775.100.087.645.390

Synonym(s)

Fatty Liver, Alcoholic

Alcoholic Fatty Liver Disease

Alcoholic fatty liver

Alcoholic fatty liver disease

FATTY LIVER ALCOHOLIC

Fatty liver alcoholic

alcohol; fatty degeneration of liver

alcohol; liver degeneration, fatty

alcoholic fatty liver

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Acetaldehyde	20118189	CTD
2	Alcohols	View details 4735055 12036955 15016835 17920746 18703563 19951287 20007851 20116195 20118189 21449565 22019745 22138249 22413959 24498295 24892905 24946281 25455889 25927324 26747958 27688165 27795452 27837167 28131861 28419832 28803762 28852734 28964808	CTD
3	Apigenin	28803762	CTD
4	Berberine	25455889	CTD
5	Betaine	20118189	CTD
6	Carvedilol	22413959	CTD
7	Chlormethiazole	24892905	CTD
8	Choline	20118189	CTD
9	Clofibrate	15016835	CTD
10	Ellagic Acid	24498295	CTD
11	Folic Acid	20118189	CTD
12	Methionine	20118189	CTD
13	Resveratrol	24498295	CTD
14	Rosiglitazone	20007851	CTD
15	Selenium	4735055	CTD
16	Silymarin	27795452	CTD
17	Vitamin B 12	20118189	CTD
18	Vitamin E	4735055	CTD
19	Zinc Sulfate	20118189	CTD
20	acanthoic acid	28964808	CTD
21	allyl sulfide	22138249	CTD
22	cobaltiprotoporphyrin	24946281	CTD
23	dihydromyricetin	28419832	CTD
24	platycodin D	25927324 28852734	CTD
25	tetramethylpyrazine	27837167	CTD
26	thymoquinone	27688165	CTD
27	zinc protoporphyrin	26747958	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hepatitis, Alcoholic	51.9%
2	Liver Cirrhosis, Alcoholic	51.9%
3	Non-alcoholic Fatty Liver Disease	32.9%
4	Hepatitis	30.1%
5	Portal Hypertension	30.1%
6	Liver Cirrhosis	30.1%
7	Focal Nodular Hyperplasia	30.1%
8	Hepatic Insufficiency	30.1%
9	Biliary cirrhosis	29%
10	Liver neoplasms	27%
11	Chemical and Drug Induced Liver Injury	25.6%
12	Liver Diseases, Parasitic	25.1%
13	Hepatic Veno-Occlusive Disease	24.4%
14	Peliosis Hepatis	24.4%
15	Hepatopulmonary Syndrome	24.4%
16	Hepatomegaly	24.1%
17	Hepatic Vein Thrombosis	23.8%
18	Liver Abscess	23.8%
19	Budd-Chiari Syndrome	23.8%
20	Reye Syndrome	21.9%
21	Esophageal and Gastric Varices	21.1%
22	Pancreatitis, Alcoholic	20%
23	Hepatorenal Syndrome	19.9%
24	Liver Abscess, Amebic	19.9%
25	Hepatitis, Chronic	19.8%
26	Liver Failure	19.8%
27	Chronic active hepatitis	19.8%
28	Biliary Tract Diseases	17.3%
29	Gastrointestinal Diseases	17.3%
30	Pancreatic Diseases	17.3%
31	Porphyrias, Hepatic	17.2%
32	Hepatitis, Animal	16.5%
33	Hepatitis, Viral, Human	16.5%
34	Chemical and Drug Induced Liver Injury, Chronic	16%
35	Liver Cirrhosis, Experimental	15.8%
36	Hepatitis B, Chronic	15.3%
37	Hepatitis C, Chronic	15.3%
38	Fatty Liver	15.1%
39	Steatohepatitis	15.1%
40	Hepatocellular Adenoma	15%
41	Cardiomyopathy, Alcoholic	14.8%
42	Liver Failure, Acute	14.7%
43	End Stage Liver Disease	14.7%
44	Zollinger-Ellison syndrome	14.1%
45	Digestive System Neoplasms	13.9%
46	Alcohol-Induced Disorders, Nervous System	13.9%
47	Gastrointestinal Neoplasms	13.5%
48	Pancreatic Fistula	13.4%
49	Fascioliasis	13.4%
50	Echinococcosis, Hepatic	13.3%
51	Liver Neoplasms, Experimental	13.3%
52	Fatty Liver, Alcoholic	13.1%
53	Fetal Alcohol Spectrum Disorders	12.5%
54	Massive Hepatic Necrosis	12.2%
55	Autoimmune hepatitis	12%
56	Psychoses, Alcoholic	11.7%
57	Peritoneal Neoplasms	11.6%
58	Alcohol Use Disorder	11.6%
59	Alcoholic Intoxication	11.6%
60	Alcohol abuse	11.6%
61	Bile Duct Neoplasms	11.3%
62	gallbladder neoplasm	11.3%
63	Intestinal Neoplasms	11.3%
64	Stomach Neoplasms	11.3%
65	Mesenteric vascular insufficiency	11.3%
66	Variegate Porphyria	11.2%
67	Acute intermittent porphyria	11.2%
68	Porphyria Cutanea Tarda	11.2%
69	Esophageal Atresia	11.1%
70	Intestinal Atresia	11.1%
71	Mesenteric Vascular Occlusion	11.1%
72	Intestinal Fistula	11.1%
73	Enterocutaneous Fistula	11.1%
74	Proctocolitis	10.9%
75	Colorectal Neoplasms	10.8%
76	Dysentery	10.6%
77	Enteritis	10.6%
78	Enterocolitis	10.6%
79	Esophagitis	10.6%
80	Gastritis	10.6%
81	Inflammatory Bowel Diseases	10.6%
82	Cholecystolithiasis	10.6%
83	Hepatitis, Viral, Animal	10.3%
84	Pancreatic Neoplasm	10.2%
85	Hepatitis E	10.1%
86	Bile Duct Diseases	10%
87	Cholelithiasis	10%
88	Chylous Ascites	10%
89	Esophageal Diseases	10%
90	Gastroenteritis	10%
91	Intestinal Diseases	10%
92	Pancreatic Insufficiency	10%
93	Pancreatitis	10%
94	Pneumoperitoneum	10%
95	Stomach Diseases	10%
96	Hepatitis B	10%
97	Hepatitis C	10%
98	Hepatitis A	9.9%
99	Esophageal Neoplasms	9.9%
100	Hepatic Encephalopathy	9.8%
101	Duodenitis	9.8%
102	Ileitis	9.8%
103	Erosive Duodenitis	9.8%
104	Cecal Neoplasms	9.7%
105	Duodenal Neoplasms	9.7%
106	Choledochal Cyst	9.6%
107	Binge Drinking	9.6%
108	Rectal Fistula	9.3%
109	Anal Fistula	9.3%
110	Colitis	9.2%
111	Duodenogastric Reflux	9.2%
112	Peptic Ulcer	9.2%
113	Proctitis	9.2%
114	Choledocholithiasis	9.2%
115	Marijuana Abuse	9.2%
116	Opioid-Related Disorders	9.2%
117	Nicotine Dependence	9.2%
118	Opioid abuse	9.2%
119	Phencyclidine Abuse	9.2%
120	Substance Abuse, Intravenous	9.2%
121	Substance Withdrawal Syndrome	9.2%
122	Tobacco Use Disorder	9.2%
123	Amphetamine-Related Disorders	9.2%
124	Cocaine-Related Disorders	9.2%
125	Zellweger Syndrome	9.1%
126	Drug Overdose	9%
127	Gastrointestinal Stromal Tumors	8.8%
128	Alcohol Withdrawal Delirium	8.8%
129	Psychoses, Substance-Induced	8.8%
130	Alcohol Withdrawal Seizures	8.7%
131	Hepatolenticular Degeneration	8.4%
132	Anus Neoplasms	8.2%
133	Sigmoid Neoplasms	8.2%
134	Pancreatic Cyst	8.1%
135	Pouchitis	8.1%
136	Anus, Imperforate	8%
137	Gastrointestinal Hemorrhage	8%
138	Hemoperitoneum	8%
139	Mesenteric Panniculitis	8%
140	Panniculitis, Peritoneal	8%
141	Peritonitis	8%
142	Peritoneal Fibrosis	8%
143	Encapsulating Peritoneal Sclerosis	8%
144	Anorectal Malformations	8%
145	Appendiceal Neoplasms	8%
146	Colonic Neoplasms	8%
147	Rectal Neoplasms	8%
148	Biliary Fistula	8%
149	Gastric Fistula	8%
150	Tuberculosis, Gastrointestinal	7.9%
151	Crohn Disease	7.8%
152	Duodenal Obstruction	7.8%
153	Enterocolitis, Neutropenic	7.8%
154	Necrotizing Enterocolitis	7.8%
155	Neonatal Abstinence Syndrome	7.7%
156	Appendicitis	7.7%
157	Drug toxicity	7.4%
158	Poisoning	7.4%
159	Wernicke Encephalopathy	7.2%
160	Duodenal Ulcer	7.1%
161	Peptic Ulcer Perforation	7.1%
162	Gastric ulcer	7.1%
163	Adenomatous Polyposis Coli	7%
164	Cecal Diseases	6.6%
165	Cholangitis	6.6%
166	Cholecystitis	6.6%
167	Cholestasis	6.6%
168	Colonic Diseases	6.6%
169	Common Bile Duct Diseases	6.6%
170	Esophageal Stenosis	6.6%
171	Ileal Diseases	6.6%
172	Intestinal Obstruction	6.6%
173	Intestinal Perforation	6.6%
174	Jejunal Diseases	6.6%
175	Pneumatosis Cystoides Intestinalis	6.6%
176	Rectal Diseases	6.6%
177	Gastric Dilatation	6.6%
178	Pancreatitis, Chronic	6.6%
179	Gastric outlet obstruction	6.6%
180	Cronkhite-Canada Syndrome	6.6%
181	Intestinal Polyposis	6.6%
182	Enterocolitis, Pseudomembranous	6.5%
183	pseudomembranous colitis	6.5%
184	Dysentery, Bacillary	6.5%
185	Colonic Pseudo-Obstruction	6.1%
186	Colitis, Ischemic	6%
187	Cystic Fibrosis	5.9%
188	Congenital Hyperinsulinism	5.7%
189	Rift Valley Fever	5.6%
190	Esophageal Perforation	5.5%
191	Intestinal Diseases, Parasitic	5.5%
192	Barrett Esophagus	5.4%
193	Deglutition Disorders	5.4%
194	Achlorhydria	5.3%
195	Pancreatic Pseudocyst	5.3%
196	Gastric Antral Vascular Ectasia	5.3%
197	Peptic Ulcer Hemorrhage	5.2%
198	Gastroparesis	5.2%
199	Carcinoma, Pancreatic Ductal	5.2%
200	Heroin Dependence	5%
201	Morphine Dependence	5%
202	Cholestasis, Extrahepatic	4.9%
203	Biliary Dyskinesia	4.9%
204	Cholangitis, Sclerosing	4.9%
205	Colonic Diseases, Functional	4.9%
206	Esophageal motility disorders	4.9%
207	Fecal Incontinence	4.9%
208	Fecal Impaction	4.9%
209	Intussusception	4.9%
210	Mallory-Weiss Syndrome	4.9%
211	Megacolon	4.9%
212	Pyloric Stenosis	4.9%
213	Acalculous Cholecystitis	4.9%
214	Ileus	4.9%
215	Meconium ileus	4.9%
216	Melena	4.4%
217	Hematemesis	4.4%
218	insulinoma	4.3%
219	Gastrinoma	4.3%
220	Glucagonoma	4.3%
221	Esophageal Achalasia	4.1%
222	Anal Fissure	4.1%
223	Intestinal Pseudo-Obstruction	4.1%
224	Irritable Bowel Syndrome	4.1%
225	Superior Mesenteric Artery Syndrome	4.1%
226	Emphysematous Cholecystitis	4.1%
227	Neurogenic Bowel	4.1%
228	Sphincter of Oddi Dysfunction	4.1%
229	Anal Ulcer	4.1%
230	Hemorrhoids	4%
231	Afferent Loop Syndrome	3.9%
232	Celiac Disease	3.9%
233	Short Bowel Syndrome	3.9%
234	Sprue, Tropical	3.9%
235	Steatorrhea	3.9%
236	Rectocele	3.9%
237	Sprue	3.9%
238	Diverticulitis	3.9%
239	Dumping Syndrome	3.9%
240	Rectal Prolapse	3.9%
241	Vipoma	3.9%
242	Fluoride Poisoning	3.8%
243	Food Poisoning	3.8%
244	Gas Poisoning	3.8%
245	Mycotoxicosis	3.8%
246	Plant Poisoning	3.8%
247	Anticholinergic Syndrome	3.8%
248	Serotonin Syndrome	3.8%
249	Organophosphate poisoning	3.8%
250	Propofol Infusion Syndrome	3.8%
251	Nesidioblastosis	3.7%
252	Giardiasis	3.4%
253	Diverticulum	3.3%
254	Diverticulosis	3.3%
255	Mushroom Poisoning	3.3%
256	Pruritus Ani	3.3%
257	Bites and Stings	3.1%
258	Neurotoxicity Syndromes	3.1%
259	Metabolic Side Effects of Drugs and Substances	3.1%
260	Water Intoxication	3%
261	Injection Site Reaction	3%
262	Arsenic Poisoning	3%
263	Infusion site reaction	3%
264	Laryngopharyngeal Reflux	3%
265	Akathisia, Drug-Induced	2.9%
266	Peutz-Jeghers Syndrome	2.8%
267	Lactose Intolerance	2.8%
268	Dyskinesia, Drug-Induced	2.6%
269	Cryptosporidiosis	2.2%
270	Cardiotoxicity	2.2%
271	Cadmium poisoning	2.1%
272	Carbon Monoxide Poisoning	2.1%
273	Ciguatera Poisoning	2.1%
274	Ergotism	2.1%
275	Lead Poisoning	2.1%
276	Mercury Poisoning	2.1%
277	Shellfish Poisoning	2.1%
278	CREST Syndrome	1.8%
279	Insect Bites and Stings	1.7%
280	Argyria	1.7%
281	Manganese Poisoning	1.7%
282	Salmonella food poisoning	1.6%
283	Neuroleptic Malignant Syndrome	1.4%
284	Drug Eruptions	1.4%
285	Botulism	1.2%
286	MPTP Poisoning	1.2%
287	Asthma, Aspirin-Induced	1%
288	Mercury Poisoning, Nervous System	1%
289	Lead Poisoning, Nervous System	1%
290	Tick Paralysis	0.8%
291	Acute Generalized Exanthematous Pustulosis	0.8%
292	Erythema Nodosum	0.7%
293	Serum Sickness	0.7%
294	Lead Poisoning, Nervous System, Childhood	0.6%
295	Lead Poisoning, Nervous System, Adult	0.6%
296	Acrodynia	0.5%
297	Toxic Epidermal Necrolysis	0.5%
298	Stevens-Johnson Syndrome	0.5%

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