MetaADEDB 2.0 @ LMMD
Hydroxychloroquine
(XXSMGPRMXLTPCZ-UHFFFAOYSA-N)
Structure
SMILES
OCCN(CCCC(Nc1ccnc2c1ccc(c2)Cl)C)CC
Type(s)
Approved
ATC code(s)
P01BA02
Molecular Formula:
C18H26ClN3O
Molecular Weight:
335.872
Log P:
3.8560
Hydrogen Bond Acceptor:
4
Hydrogen Bond Donor:
2
TPSA:
48.39
CAS Number(s):
118-42-3
Synonym(s)
1.
Hydroxychloroquine
2.
Hydroxychlorochin
3.
Oxychlorochin
4.
Oxychloroquine
5.
Hydroxychloroquine Sulfate
6.
Hydroxychloroquine Sulfate (1:1) Salt
7.
Plaquenil
External Link(s)
MeSHD006886
PubChem Compound3652
ChEBI5801
CHEMBLCHEMBL1535
DrugBankDB01611
DrugCentral1395
IUPHAR/BPS Guide to PHARMACOLOGY7198
KEGGcpd:C07043
dr:D08050
Therapeutic Target DatabaseD0OJ4L
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1HypersensitivityFAERS: 73
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
2Toxicity to various agentsFAERS: 58
Canada Vigilance: 1
Canada Vigilance
US FAERS
3Retinal toxicityFAERS: 51
Canada Vigilance: 10
Canada Vigilance
US FAERS
4Drug ineffectiveFAERS: 45
Canada Vigilance: 97
Canada Vigilance
US FAERS
5NauseaFAERS: 38
Canada Vigilance: 7
Canada Vigilance
OFFSIDES
SIDER
US FAERS
6Visual ImpairmentFAERS: 38
Canada Vigilance: 4
Canada Vigilance
SIDER
US FAERS
7PruritusFAERS: 36
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
8Abdominal discomfortFAERS: 32
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
US FAERS
9Product substitution issueFAERS: 29
Canada Vigilance: 61
Canada Vigilance
US FAERS
10DizzinessFAERS: 28
Canada Vigilance: 2
8219437
10229401
CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
11HeadacheFAERS: 26
Canada Vigilance: 3
10229401CTD
SIDER
Canada Vigilance
US FAERS
12PainFAERS: 24
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
SIDER
US FAERS
13UrticariaFAERS: 24
Canada Vigilance: 2
17162415CTD
SIDER
Canada Vigilance
US FAERS
14VomitingFAERS: 22
Canada Vigilance: 5
Canada Vigilance
SIDER
US FAERS
15OverdoseFAERS: 20
Canada Vigilance: 1
Canada Vigilance
US FAERS
16AlopeciaFAERS: 19
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
SIDER
US FAERS
17FatigueFAERS: 19
Canada Vigilance: 5
Canada Vigilance
OFFSIDES
SIDER
US FAERS
18HypotensionFAERS: 18
Canada Vigilance: 1
15582773CTD
Canada Vigilance
US FAERS
19ErythemaFAERS: 17OFFSIDES
US FAERS
20Product use in unapproved indicationFAERS: 17
Canada Vigilance: 1
Canada Vigilance
US FAERS
21SomnolenceFAERS: 15
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
22Stevens-Johnson SyndromeFAERS: 15
Canada Vigilance: 3
25811541CTD
SIDER
Canada Vigilance
US FAERS
23Atrial FibrillationFAERS: 14
Canada Vigilance: 1
Canada Vigilance
US FAERS
24Ejection Fraction DecreasedFAERS: 14US FAERS
25AstheniaFAERS: 13
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
26Erythema MultiformeFAERS: 13SIDER
US FAERS
27Macular degenerationFAERS: 134875645CTD
SIDER
US FAERS
28MyopathyFAERS: 13
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
29PalpitationsFAERS: 13
Canada Vigilance: 1
Canada Vigilance
US FAERS
30Retinal DegenerationFAERS: 13US FAERS
31Rheumatoid ArthritisFAERS: 13
Canada Vigilance: 4
Canada Vigilance
US FAERS
32Suicide attemptFAERS: 13US FAERS
33Abdominal PainFAERS: 12
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
34EosinophiliaFAERS: 12SIDER
US FAERS
35MalaiseFAERS: 12
Canada Vigilance: 3
Canada Vigilance
US FAERS
36TinnitusFAERS: 12
Canada Vigilance: 4
Canada Vigilance
SIDER
US FAERS
37Weight decreasedFAERS: 12SIDER
US FAERS
38Drug exposure during pregnancyFAERS: 11US FAERS
39Left Ventricular HypertrophyFAERS: 11US FAERS
40Pharmaceutical product complaintFAERS: 11US FAERS
41Rash erythematousFAERS: 11
Canada Vigilance: 1
Canada Vigilance
US FAERS
42Retinal DetachmentFAERS: 11
Canada Vigilance: 1
Canada Vigilance
US FAERS
43treatment failureFAERS: 11
Canada Vigilance: 1
Canada Vigilance
US FAERS
44ArthralgiaFAERS: 10
Canada Vigilance: 4
Canada Vigilance
US FAERS
45Blood creatine phosphokinase increasedFAERS: 10
Canada Vigilance: 2
Canada Vigilance
US FAERS
46CardiotoxicityFAERS: 10US FAERS
47CataractFAERS: 10
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
US FAERS
48Chest PainFAERS: 10
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
49Product quality issueFAERS: 10US FAERS
50Retinal depigmentationFAERS: 10US FAERS
51Septic ShockFAERS: 10US FAERS
52SwellingFAERS: 10
Canada Vigilance: 1
Canada Vigilance
US FAERS
53AnxietyFAERS: 9
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
54Cardiac septal hypertrophyFAERS: 9US FAERS
55ChillsFAERS: 9
Canada Vigilance: 1
Canada Vigilance
US FAERS
56PhotophobiaFAERS: 9
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
57BlindnessFAERS: 8US FAERS
58Brain natriuretic peptide abnormalFAERS: 8US FAERS
59Burning sensationFAERS: 8OFFSIDES
US FAERS
60Diastolic dysfunctionFAERS: 8US FAERS
61Disease ProgressionFAERS: 8US FAERS
62Disease recurrenceFAERS: 8US FAERS
63DyspepsiaFAERS: 8
Canada Vigilance: 2
Canada Vigilance
US FAERS
64Feeling abnormalFAERS: 8
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
65TachycardiaFAERS: 8US FAERS
66EndocarditisFAERS: 7US FAERS
67Myasthenia GravisFAERS: 7US FAERS
68Posterior reversible encephalopathy syndromeFAERS: 7US FAERS
69Retinal pigment epitheliopathyFAERS: 7US FAERS
70Right Ventricular HypertrophyFAERS: 7US FAERS
71Sick Sinus SyndromeFAERS: 7US FAERS
72Toxic Epidermal NecrolysisFAERS: 7SIDER
US FAERS
73ArthritisFAERS: 6
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
74DysgeusiaFAERS: 6OFFSIDES
US FAERS
75FlatulenceFAERS: 6OFFSIDES
US FAERS
76Mental status changesFAERS: 6US FAERS
77NeutropeniaFAERS: 6US FAERS
78Ocular ToxicityFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
79PsoriasisFAERS: 6
Canada Vigilance: 1
12852373CTD
SIDER
Canada Vigilance
US FAERS
80Respiratory FailureFAERS: 6OFFSIDES
US FAERS
81Restrictive cardiomyopathyFAERS: 6US FAERS
82Skin lesionFAERS: 6OFFSIDES
US FAERS
83Visual disturbanceFAERS: 6OFFSIDES
SIDER
US FAERS
84Alanine Aminotransferase IncreasedFAERS: 5OFFSIDES
US FAERS
85AtaxiaFAERS: 5SIDER
US FAERS
86Atrioventricular BlockFAERS: 5US FAERS
87CardiomegalyFAERS: 5US FAERS
88CellulitisFAERS: 5US FAERS
89DeafnessFAERS: 5SIDER
US FAERS
90Drug toxicityFAERS: 5OFFSIDES
US FAERS
91General physical health deteriorationFAERS: 5US FAERS
92HypoxiaFAERS: 5US FAERS
93InflammationFAERS: 5
Canada Vigilance: 2
Canada Vigilance
US FAERS
94Left atrial dilatationFAERS: 5US FAERS
95Low birth weight babyFAERS: 5US FAERS
96OtotoxicityFAERS: 5US FAERS
97PancytopeniaFAERS: 5SIDER
US FAERS
98Pityriasis Lichenoides et Varioliformis AcutaFAERS: 5US FAERS
99PneumoniaFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
100PolyneuropathyFAERS: 5US FAERS
101SyncopeFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
102Transaminases increasedFAERS: 5US FAERS
103TremorFAERS: 58219437CTD
US FAERS
104Troponin I increasedFAERS: 5US FAERS
105Unevaluable eventFAERS: 5US FAERS
106VasculitisFAERS: 5US FAERS
107Adverse eventFAERS: 4OFFSIDES
US FAERS
108AmnesiaFAERS: 4US FAERS
109Aspartate Aminotransferase IncreasedFAERS: 4US FAERS
110Back PainFAERS: 4US FAERS
111Eye painFAERS: 4
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
112Febrile NeutropeniaFAERS: 4US FAERS
113Feeling ColdFAERS: 4US FAERS
114FlushingFAERS: 4US FAERS
115InfectionFAERS: 4US FAERS
116Lip swellingFAERS: 4US FAERS
117Memory impairmentFAERS: 4US FAERS
118MyalgiaFAERS: 4
Canada Vigilance: 2
Canada Vigilance
US FAERS
119Myocardial necrosis marker increasedFAERS: 4US FAERS
120NervousnessFAERS: 4SIDER
US FAERS
121PancreatitisFAERS: 4OFFSIDES
US FAERS
122Peripheral swellingFAERS: 4US FAERS
123Retinogram abnormalFAERS: 4
Canada Vigilance: 3
Canada Vigilance
US FAERS
124Sinus bradycardiaFAERS: 4OFFSIDES
US FAERS
125Splenic InfarctionFAERS: 4US FAERS
126Status EpilepticusFAERS: 4US FAERS
127Therapeutic response unexpected with drug substitutionFAERS: 4US FAERS
128VertigoFAERS: 4
Canada Vigilance: 1
1173923CTD
SIDER
Canada Vigilance
US FAERS
129Autoimmune hepatitisFAERS: 3US FAERS
130Blood potassium decreasedFAERS: 3OFFSIDES
US FAERS
131Cerebrovascular accidentFAERS: 3US FAERS
132CheilitisFAERS: 3US FAERS
133Complex partial seizuresFAERS: 3US FAERS
134Coronary Artery DiseaseFAERS: 3US FAERS
135CytopeniaFAERS: 3US FAERS
136Deafness NeurosensoryFAERS: 3
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
137Deposit eyeFAERS: 3US FAERS
138DisorientationFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
139DysarthriaFAERS: 3US FAERS
140Enterococcus test positiveFAERS: 3US FAERS
141EpiglottitisFAERS: 3US FAERS
142Fluid overloadFAERS: 3US FAERS
143Hepatic EncephalopathyFAERS: 3US FAERS
144Hepatitis BFAERS: 3US FAERS
145HepatitisFAERS: 3US FAERS
146Impaired work abilityFAERS: 3US FAERS
147Joint swellingFAERS: 3US FAERS
148LethargyFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
149Lyme DiseaseFAERS: 3US FAERS
150Macular pigmentationFAERS: 3SIDER
US FAERS
151MyocarditisFAERS: 316040888CTD
US FAERS
152Nail pigmentationFAERS: 3US FAERS
153Night sweatsFAERS: 3US FAERS
154Optic AtrophyFAERS: 3SIDER
US FAERS
155Pericardial effusionFAERS: 3OFFSIDES
US FAERS
156Product use issueFAERS: 3
Canada Vigilance: 2
Canada Vigilance
US FAERS
157ProteinuriaFAERS: 3US FAERS
158Pulmonary HypertensionFAERS: 3US FAERS
159PurpuraFAERS: 3US FAERS
160Pustular psoriasisFAERS: 3US FAERS
161QRS axis abnormalFAERS: 3US FAERS
162Reaction to excipientFAERS: 3US FAERS
163RestlessnessFAERS: 3US FAERS
164RetinitisFAERS: 3US FAERS
165Right atrial dilatationFAERS: 3US FAERS
166Sinus TachycardiaFAERS: 3US FAERS
167Staphylococcus test positiveFAERS: 3US FAERS
168Therapy non-responderFAERS: 3US FAERS
169ThrombocytopeniaFAERS: 3SIDER
US FAERS
170Vitreous floatersFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
171White blood cell count decreasedFAERS: 3US FAERS
172AbasiaFAERS: 2OFFSIDES
US FAERS
173AcneFAERS: 2US FAERS
174Activities of daily living impairedFAERS: 2US FAERS
175Acute respiratory failureFAERS: 2OFFSIDES
US FAERS
176AngerFAERS: 2OFFSIDES
US FAERS
177Angina PectorisFAERS: 2US FAERS
178AsthmaFAERS: 2OFFSIDES
US FAERS
179AtelectasisFAERS: 2US FAERS
180Atrial FlutterFAERS: 2US FAERS
181Blighted ovumFAERS: 2US FAERS
182Blood alkaline phosphatase increasedFAERS: 2OFFSIDES
US FAERS
183Blood glucose decreasedFAERS: 2US FAERS
184Blood immunoglobulin A decreasedFAERS: 2US FAERS
185Blood immunoglobulin A increasedFAERS: 2US FAERS
186Blood pressure fluctuationFAERS: 2US FAERS
187BradycardiaFAERS: 2US FAERS
188Cardiac HypertrophyFAERS: 2US FAERS
189Chorioretinal atrophyFAERS: 2US FAERS
190ChromaturiaFAERS: 2US FAERS
191Coma scale abnormalFAERS: 2US FAERS
192ConjunctivitisFAERS: 2US FAERS
193CryingFAERS: 2US FAERS
194Depressed Level of ConsciousnessFAERS: 2US FAERS
195Depressed moodFAERS: 2OFFSIDES
US FAERS
196Detachment of retinal pigment epitheliumFAERS: 2US FAERS
197DiscomfortFAERS: 2US FAERS
198Drug prescribing errorFAERS: 2US FAERS
199DyschromatopsiaFAERS: 2US FAERS
200DysphoniaFAERS: 2US FAERS
201DysuriaFAERS: 2US FAERS
202EczemaFAERS: 2US FAERS
203Electrolyte imbalanceFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
204Emotional distressFAERS: 2OFFSIDES
US FAERS
205EpistaxisFAERS: 2US FAERS
206Extraocular Muscle ParesisFAERS: 2US FAERS
207Fundoscopy abnormalFAERS: 2US FAERS
208GastritisFAERS: 2US FAERS
209Gingival HypertrophyFAERS: 2US FAERS
210GlaucomaFAERS: 2
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
US FAERS
211Gluten sensitivityFAERS: 2US FAERS
212Incorrect dose administeredFAERS: 2OFFSIDES
US FAERS
213Intentional product misuseFAERS: 2US FAERS
214LeukopeniaFAERS: 2SIDER
US FAERS
215Lupus enteritisFAERS: 2US FAERS
216LymphadenopathyFAERS: 2US FAERS
217Macular fibrosisFAERS: 2US FAERS
218MaculeFAERS: 2US FAERS
219Maternal exposure during pregnancyFAERS: 2US FAERS
220Medication ErrorFAERS: 2US FAERS
221Mental impairmentFAERS: 2US FAERS
222Metabolic acidosisFAERS: 2
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
223Muscle tightnessFAERS: 2US FAERS
224Musculoskeletal discomfortFAERS: 2US FAERS
225Musculoskeletal stiffnessFAERS: 2OFFSIDES
US FAERS
226MydriasisFAERS: 2US FAERS
227MyelofibrosisFAERS: 2US FAERS
228NephritisFAERS: 2US FAERS
229Neutrophil count decreasedFAERS: 2US FAERS
230No adverse eventFAERS: 2US FAERS
231Oral mucosal erythemaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
232Personality ChangeFAERS: 2US FAERS
233PetechiaeFAERS: 2US FAERS
234Placental InsufficiencyFAERS: 2US FAERS
235PoisoningFAERS: 2US FAERS
236Portal HypertensionFAERS: 2US FAERS
237Post procedural complicationFAERS: 2US FAERS
238PregnancyFAERS: 2US FAERS
239Respiratory DepressionFAERS: 2US FAERS
240Retinal Vein OcclusionFAERS: 2US FAERS
241Retinal depositsFAERS: 2US FAERS
242RhabdomyolysisFAERS: 2US FAERS
243Rheumatoid NoduleFAERS: 2US FAERS
244ScotomaFAERS: 211992862
15834087
18215798
CTD
SIDER
US FAERS
245SepsisFAERS: 2US FAERS
246ShockFAERS: 2US FAERS
247Sjogren's SyndromeFAERS: 2US FAERS
248Skin tightnessFAERS: 2OFFSIDES
US FAERS
249StomatitisFAERS: 2US FAERS
250Swelling of eyelidFAERS: 2US FAERS
251TachyarrhythmiaFAERS: 2US FAERS
252Therapeutic response changedFAERS: 2
Canada Vigilance: 4
Canada Vigilance
US FAERS
253Tonic clonic movementsFAERS: 2US FAERS
254Ventricular hypertrophyFAERS: 2US FAERS
255Ventricular hypokinesiaFAERS: 2US FAERS
256ZygomycosisFAERS: 2US FAERS
257jaundiceFAERS: 2US FAERS
258Abnormal weight gainFAERS: 1US FAERS
259Accidental deathFAERS: 1US FAERS
260Accidental exposureFAERS: 1OFFSIDES
US FAERS
261Accidental overdoseFAERS: 1US FAERS
262Acute myocardial infarctionFAERS: 1US FAERS
263Acute sinusitisFAERS: 1US FAERS
264Acute vestibular syndromeFAERS: 1US FAERS
265Acute zonal occult outer retinopathyFAERS: 1US FAERS
266AdenocarcinomaFAERS: 1OFFSIDES
US FAERS
267AgitationFAERS: 1SIDER
US FAERS
268Allergic reaction to excipientFAERS: 1US FAERS
269Altered state of consciousnessFAERS: 1US FAERS
270Amylase increasedFAERS: 1US FAERS
271Anaphylactic shockFAERS: 1US FAERS
272AngioedemaFAERS: 1SIDER
US FAERS
273Angiogram abnormalFAERS: 1US FAERS
274AnorexiaFAERS: 1OFFSIDES
SIDER
US FAERS
275AnosmiaFAERS: 1US FAERS
276Antiacetylcholine receptor antibody positiveFAERS: 1US FAERS
277Antibody test positiveFAERS: 1US FAERS
278Antiphospholipid SyndromeFAERS: 1US FAERS
279AnuriaFAERS: 1US FAERS
280AphoniaFAERS: 1US FAERS
281ArthropathyFAERS: 1OFFSIDES
US FAERS
282AscitesFAERS: 1US FAERS
283AsphyxiaFAERS: 1US FAERS
284Autoimmune retinopathyFAERS: 1US FAERS
285BedriddenFAERS: 1US FAERS
286BlepharospasmFAERS: 1US FAERS
287Blood albumin decreasedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
288Blood chloride decreasedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
289Blood creatine phosphokinase abnormalFAERS: 1US FAERS
290Blood creatinine increasedFAERS: 1US FAERS
291Blood osmolarity increasedFAERS: 1US FAERS
292Blood pH decreasedFAERS: 1US FAERS
293Blood sodium decreasedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
294Bone painFAERS: 1OFFSIDES
US FAERS
295Bowel movement irregularityFAERS: 1US FAERS
296Butterfly rashFAERS: 1US FAERS
297Cerebral InfarctionFAERS: 1US FAERS
298Cerebral vasoconstrictionFAERS: 1US FAERS
299Cerebral ventricle dilatationFAERS: 1US FAERS
300Chest discomfortFAERS: 1US FAERS
301ChokingFAERS: 1US FAERS
302CholelithiasisFAERS: 1US FAERS
303Cold sweatFAERS: 1OFFSIDES
US FAERS
304ColitisFAERS: 1US FAERS
305Completed SuicideFAERS: 1US FAERS
306Complications of maternal exposure to therapeutic drugsFAERS: 1US FAERS
307Compression fractureFAERS: 1OFFSIDES
US FAERS
308Compulsive shoppingFAERS: 1US FAERS
309Congenital cerebral cystFAERS: 1US FAERS
310Congenital intestinal malformationFAERS: 1US FAERS
311Cornea verticillataFAERS: 1US FAERS
312CyanosisFAERS: 1US FAERS
313CystFAERS: 1US FAERS
314Cytolytic hepatitisFAERS: 1OFFSIDES
US FAERS
315Dark circles under eyesFAERS: 1US FAERS
316Deep Vein ThrombosisFAERS: 1US FAERS
317DeformityFAERS: 1US FAERS
318DehydrationFAERS: 1US FAERS
319DemyelinationFAERS: 1OFFSIDES
US FAERS
320DermatomyositisFAERS: 12483176CTD
US FAERS
321Detachment of macular retinal pigment epitheliumFAERS: 1US FAERS
322Device FailureFAERS: 1US FAERS
323Differential white blood cell count abnormalFAERS: 1US FAERS
324DiplopiaFAERS: 19051865CTD
US FAERS
325DisabilityFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
326DissociationFAERS: 1US FAERS
327Drug level increasedFAERS: 1US FAERS
328Drug screen false positiveFAERS: 1US FAERS
329Drug screen positiveFAERS: 1US FAERS
330Dry skinFAERS: 1US FAERS
331DysacusisFAERS: 1US FAERS
332DysmetropsiaFAERS: 1US FAERS
333DysmorphismFAERS: 1US FAERS
334DysplasiaFAERS: 1US FAERS
335Economic problemFAERS: 1US FAERS
336Electrocardiogram repolarisation abnormalityFAERS: 1US FAERS
337Embolic strokeFAERS: 1US FAERS
338EncephalitisFAERS: 1US FAERS
339Enterococcal infectionFAERS: 1US FAERS
340EnterocolitisFAERS: 1US FAERS
341EntropionFAERS: 1US FAERS
342EpidermolysisFAERS: 1US FAERS
343EpilepsyFAERS: 1US FAERS
344Erythema dyschromicum perstansFAERS: 1US FAERS
345Euphoric moodFAERS: 1US FAERS
346Exfoliative rashFAERS: 1OFFSIDES
US FAERS
347Expired product administeredFAERS: 1US FAERS
348Exposure during breast feedingFAERS: 1US FAERS
349Exposure via breast milkFAERS: 1US FAERS
350Eye InfectionFAERS: 1US FAERS
351Eye irritationFAERS: 1US FAERS
352FibromyalgiaFAERS: 1OFFSIDES
US FAERS
353FractureFAERS: 1US FAERS
354Gamma-Glutamyltransferase IncreasedFAERS: 1US FAERS
355Gastric pH decreasedFAERS: 1US FAERS
356Gastric ulcerFAERS: 1US FAERS
357Gastrointestinal PainFAERS: 1SIDER
US FAERS
358General symptomFAERS: 1OFFSIDES
US FAERS
359Genital HerpesFAERS: 1US FAERS
360Gingival RecessionFAERS: 1US FAERS
361GlossitisFAERS: 1US FAERS
362Granuloma AnnulareFAERS: 1US FAERS
363Hallucination, synaestheticFAERS: 1US FAERS
364Head discomfortFAERS: 1US FAERS
365Heart sounds abnormalFAERS: 1US FAERS
366Heart valve calcificationFAERS: 1US FAERS
367HemiparesisFAERS: 1OFFSIDES
US FAERS
368Hepatitis B surface antibody positiveFAERS: 1US FAERS
369Hepatitis CFAERS: 1US FAERS
370HepatotoxicityFAERS: 1US FAERS
371HyperkeratosisFAERS: 1OFFSIDES
US FAERS
372Hypertensive cardiomyopathyFAERS: 1US FAERS
373HypophagiaFAERS: 1US FAERS
374HypoventilationFAERS: 1US FAERS
375ImmobileFAERS: 1US FAERS
376Immune thrombocytopenic purpuraFAERS: 1US FAERS
377Impaired quality of lifeFAERS: 1US FAERS
378Incorrect drug administration durationFAERS: 1US FAERS
379Infantile apnoeic attackFAERS: 1US FAERS
380Intention tremorFAERS: 1US FAERS
381Intentional self-injuryFAERS: 1US FAERS
382Intestinal AtresiaFAERS: 1US FAERS
383IridocyclitisFAERS: 1US FAERS
384Joint stiffnessFAERS: 1US FAERS
385KeratopathyFAERS: 1
Canada Vigilance: 4
Canada Vigilance
US FAERS
386Lactose IntoleranceFAERS: 1US FAERS
387Left ventricular end-diastolic pressure increasedFAERS: 1US FAERS
388LeukocytosisFAERS: 1US FAERS
389Lichen PlanusFAERS: 1OFFSIDES
US FAERS
390Limb discomfortFAERS: 1
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
391LymphomaFAERS: 1US FAERS
392MYELODYSPLASTIC SYNDROMEFAERS: 1US FAERS
393Macular detachmentFAERS: 1US FAERS
394Macular reflex abnormalFAERS: 1US FAERS
395MalabsorptionFAERS: 1US FAERS
396Manufacturing production issueFAERS: 1US FAERS
397MastectomyFAERS: 1US FAERS
398MeningitisFAERS: 1US FAERS
399Multiple MyelomaFAERS: 1US FAERS
400Muscle necrosisFAERS: 1US FAERS
401Musculoskeletal PainFAERS: 1
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
402Myasthenic SyndromeFAERS: 1US FAERS
403Myocardial InfarctionFAERS: 1US FAERS
404Myocardial fibrosisFAERS: 1US FAERS
405Neck PainFAERS: 1US FAERS
406Neonatal gastrointestinal disorderFAERS: 1US FAERS
407NephrocalcinosisFAERS: 1US FAERS
408Nephrotic SyndromeFAERS: 17071645CTD
US FAERS
409Nerve injuryFAERS: 1US FAERS
410Neuropathic painFAERS: 1US FAERS
411NystagmusFAERS: 1SIDER
US FAERS
412Ocular vasculitisFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
413OligospermiaFAERS: 1US FAERS
414OnycholysisFAERS: 1US FAERS
415Ophthalmic vein thrombosisFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
416Ophthalmological examination abnormalFAERS: 1US FAERS
417Optic NeuropathyFAERS: 1US FAERS
418Oral candidiasisFAERS: 1US FAERS
419Oral pruritusFAERS: 1US FAERS
420Oropharyngeal painFAERS: 1
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
421Pain of skinFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
422Pancreatic CystFAERS: 1US FAERS
423PapuleFAERS: 1US FAERS
424Paranasal sinus discomfortFAERS: 1US FAERS
425Pelvic PainFAERS: 1US FAERS
426Performance status decreasedFAERS: 1US FAERS
427PericarditisFAERS: 1US FAERS
428Peripheral venous diseaseFAERS: 1US FAERS
429Persistent corneal epithelial defectFAERS: 1US FAERS
430Pharyngolaryngeal PainFAERS: 1US FAERS
431Pityriasis RoseaFAERS: 1US FAERS
432Placental hypertrophyFAERS: 1US FAERS
433PleocytosisFAERS: 1US FAERS
434PneumoperitoneumFAERS: 1US FAERS
435Polymerase chain reaction positiveFAERS: 1US FAERS
436Polymyalgia RheumaticaFAERS: 1US FAERS
437Poor quality drug administeredFAERS: 1US FAERS
438Porphyria non-acuteFAERS: 1US FAERS
439Pressure of speechFAERS: 1US FAERS
440Product coating issueFAERS: 1US FAERS
441Product counterfeitFAERS: 1US FAERS
442Product formulation issueFAERS: 1US FAERS
443Product shape issueFAERS: 1US FAERS
444Productive CoughFAERS: 1OFFSIDES
US FAERS
445QuadriparesisFAERS: 1US FAERS
446RalesFAERS: 1US FAERS
447Rash papulosquamousFAERS: 1US FAERS
448Reaction to drug excipientsFAERS: 1US FAERS
449Restless Legs SyndromeFAERS: 1US FAERS
450RetchingFAERS: 1US FAERS
451Retinal cystFAERS: 1US FAERS
452Retinal phototoxicityFAERS: 1US FAERS
453Retinal pigmentationFAERS: 1US FAERS
454Retinal telangiectasiaFAERS: 1US FAERS
455Retro-orbital neoplasmFAERS: 1US FAERS
456Right atrial enlargementFAERS: 1US FAERS
457Right atrial pressure increasedFAERS: 1US FAERS
458Right ventricular failureFAERS: 1US FAERS
459ScabFAERS: 1US FAERS
460ScleritisFAERS: 1US FAERS
461Serotonin SyndromeFAERS: 1US FAERS
462Serum SicknessFAERS: 1US FAERS
463Sinus rhythmFAERS: 1US FAERS
464SinusitisFAERS: 1US FAERS
465Skeletal dysplasiaFAERS: 1US FAERS
466Skin UlcerFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
467Skin irritationFAERS: 1US FAERS
468Skin reactionFAERS: 1US FAERS
469Skin toxicityFAERS: 1US FAERS
470Solar lentigoFAERS: 1US FAERS
471SplenomegalyFAERS: 1US FAERS
472Staphylococcal abscessFAERS: 1US FAERS
473StillbirthFAERS: 1US FAERS
474StressFAERS: 1US FAERS
475SunburnFAERS: 1US FAERS
476SynovitisFAERS: 1OFFSIDES
US FAERS
477Systemic lupus erythematosus rashFAERS: 1US FAERS
478Systolic dysfunctionFAERS: 1US FAERS
479TachyphreniaFAERS: 1US FAERS
480TalipesFAERS: 1US FAERS
481Therapeutic product contaminationFAERS: 1US FAERS
482Therapeutic product effect decreasedFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
483Therapeutic product effect incompleteFAERS: 1US FAERS
484Therapeutic response unexpectedFAERS: 1US FAERS
485Therapy cessationFAERS: 1OFFSIDES
US FAERS
486Throat cancerFAERS: 1US FAERS
487Thyroid NeoplasmFAERS: 1US FAERS
488Total bile acids increasedFAERS: 1US FAERS
489Toxic Optic NeuropathyFAERS: 1US FAERS
490TrichorrhexisFAERS: 1US FAERS
491Trigeminal NeuralgiaFAERS: 1US FAERS
492TuberculosisFAERS: 1US FAERS
493UlcerFAERS: 1OFFSIDES
US FAERS
494Unresponsive to stimuliFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
495Varicella Zoster Virus InfectionFAERS: 1US FAERS
496Vascular calcificationFAERS: 1US FAERS
497Ventricular arrhythmiaFAERS: 1US FAERS
498Vitreous DetachmentFAERS: 1US FAERS
499WheezingFAERS: 1US FAERS
500Withdrawal arrhythmiaFAERS: 1US FAERS
501Wrong drug administeredFAERS: 1US FAERS
502Wrong technique in product usage processFAERS: 1US FAERS
503XerophthalmiaFAERS: 1US FAERS
504muscle injuryFAERS: 1US FAERS
505nervous system disorderFAERS: 1SIDER
US FAERS
506Abdominal CrampsSIDER
507Abdominal bruitOFFSIDES
508Abdominal tendernessOFFSIDES
509Abnormal clotting factorOFFSIDES
510Abnormal pigmentationSIDER
511Abnormal visionOFFSIDES
512Accidental needle stickOFFSIDES
513Acid refluxOFFSIDES
514Actinic keratosisOFFSIDES
515Acute otitis mediaOFFSIDES
516Acute prerenal failureOFFSIDES
517Adrenal massOFFSIDES
518Ageusia18721220CTD
519AgranulocytosisSIDER
520Altered bowel functionOFFSIDES
521AlveolitisOFFSIDES
522AnhedoniaOFFSIDES
523Anxiety Disorders8219437CTD
524Aphthous StomatitisOFFSIDES
525AppendicitisOFFSIDES
526Application site painOFFSIDES
527Application site perspirationOFFSIDES
528Application site vesiclesOFFSIDES
529Arthritis, Psoriatic3030337CTD
530ArthrodesisOFFSIDES
531AsterixisOFFSIDES
532Back disorderOFFSIDES
533Benign neoplasm of thyroid glandOFFSIDES
534Blood 1,25-dihydroxycholecalciferol decreasedOFFSIDES
535Blood creatine phosphokinase MB increasedOFFSIDES
536Blood immunoglobulin M decreasedOFFSIDES
537Blood iron increasedOFFSIDES
538Blood magnesium decreasedOFFSIDES
539Blood sodiumOFFSIDES
540Blurred visionOFFSIDES
541Bone marrow depressionSIDER
542Breast necrosisOFFSIDES
543BronchitisOFFSIDES
544BronchospasmSIDER
545Bullous eruptionSIDER
546BunionOFFSIDES
547BursitisOFFSIDES
548CalcinosisOFFSIDES
549Cardiomyopathies

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CTD
550Cervicobrachial syndromeOFFSIDES
551Chest wall painOFFSIDES
552Cholecystitis infectiveOFFSIDES
553Chronic Obstructive Airway DiseaseOFFSIDES
554Chronic sinusitisOFFSIDES
555CirrhosisOFFSIDES
556ClaustrophobiaOFFSIDES
557Colonic Diseases10220819CTD
558Color blindnessOFFSIDES
559Congenital cystic kidney diseaseOFFSIDES
560Congenital tricuspid valve incompetenceOFFSIDES
561Connective Tissue Diseases

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CTD
562Cystic Fibrosis19747007CTD
563Cytomegalovirus chorioretinitisOFFSIDES
564Deglutition Disorders17803043CTD
565Dental abscessOFFSIDES
566Dermatitis7452649CTD
SIDER
567Diabetes mellitus inadequate controlOFFSIDES
568Diaphragmatic HerniaOFFSIDES
569DiarrheaOFFSIDES
570Dieulafoy's vascular malformationOFFSIDES
571DiverticulitisOFFSIDES
572DiverticulumOFFSIDES
573DrowsinessSIDER
574Drug delivery system malfunctionOFFSIDES
575Drug dose omissionOFFSIDES
576Drug withdrawal headacheOFFSIDES
577Electrocardiogram ST segment abnormalOFFSIDES
578Emotional disorderOFFSIDES
579Eosinophilic myocarditisOFFSIDES
580Erosive gastritisOFFSIDES
581Erythema InfectiosumOFFSIDES
582Erythema annulare centrifugumSIDER
583Eustachian tube disorderOFFSIDES
584Exanthema10229401CTD
585ExcitabilitySIDER
586ExcoriationOFFSIDES
587Extremity contractureOFFSIDES
588Eye RednessOFFSIDES
589FormicationOFFSIDES
590FrustrationOFFSIDES
591GamblingOFFSIDES
592GangreneOFFSIDES
593Gastric infectionOFFSIDES
594Gastrointestinal Diseases10229401CTD
595GlobulinuriaOFFSIDES
596Goiter14723259CTD
597Hearing Loss10229401CTD
598Heart Block8378663CTD
599Heart failure3796692CTD
600HemicephalalgiaOFFSIDES
601HemiplegiaOFFSIDES
602Hepatic congestionOFFSIDES
603Hip surgeryOFFSIDES
604HyperpigmentationOFFSIDES
605Hypertensive heart diseaseOFFSIDES
606Hypokalemia15582773
16142151
CTD
607HypokinesiaSIDER
608HysterectomyOFFSIDES
609Idiosyncratic drug reactionOFFSIDES
610Inappropriate schedule of drug administrationOFFSIDES
611Inappropriate schedule of product administrationCanada Vigilance: 1Canada Vigilance
612Injection site dermatitisOFFSIDES
613Injection site erythemaOFFSIDES
614Injection site irritationOFFSIDES
615Injection site pruritusOFFSIDES
616Intermittent headacheSIDER
617Intraocular pressure test abnormalCanada Vigilance: 1Canada Vigilance
618Joint Range of Motion DecreasedOFFSIDES
619Joint sprainOFFSIDES
620Kidney FailureOFFSIDES
621LassitudeSIDER
622LeukodermaSIDER
623LeukoencephalopathyOFFSIDES
624LightheadednessSIDER
625Limb injuryOFFSIDES
626Limb operationOFFSIDES
627Liver Failure, Acute8175002CTD
628LividitySIDER
629Long QT Syndrome16615675CTD
630Lupus Erythematosus, Cutaneous20109393CTD
631Lupus Erythematosus, Discoid3796692
8949524
19076781
CTD
632Lupus Erythematosus, Systemic

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CTD
633Lupus NephritisOFFSIDES
634Lymphocyte count decreasedOFFSIDES
635Malaria17202178
18061791
CTD
636MalnutritionSIDER
637Medical device complicationOFFSIDES
638MetamorphopsiaOFFSIDES
639Mixed Connective Tissue Disease12427911CTD
640Mononucleosis syndromeOFFSIDES
641Mood swingsSIDER
642Mucosal pigmentationSIDER
643Multiple allergiesOFFSIDES
644Murphy's sign positiveOFFSIDES
645Muscle FatigueOFFSIDES
646Muscle Weakness19076781CTD
647MyelodysplasiaOFFSIDES
648NasopharyngitisOFFSIDES
649Nephritis, Interstitial15751825CTD
650Nephrogenic Fibrosing DermopathyOFFSIDES
651NephrolithiasisOFFSIDES
652Nervous tensionOFFSIDES
653Neural hearing lossSIDER
654Neutropenic sepsisOFFSIDES
655NoduleOFFSIDES
656Ocular icterusOFFSIDES
657Open reduction of fractureOFFSIDES
658Optic NeuritisOFFSIDES
659Oral fungal infectionOFFSIDES
660Oropharyngeal discomfortSIDER
661OsteomaOFFSIDES
662OsteomyelitisOFFSIDES
663OsteopeniaOFFSIDES
664OsteoporosisOFFSIDES
665PallorSIDER
666Panic DisorderOFFSIDES
667Patent ductus arteriosusCanada Vigilance: 1Canada Vigilance
668PeriarthritisOFFSIDES
669PeriodontitisOFFSIDES
670Peripheral Nervous System Diseases8219437
10219755
CTD
671Peripheral occlusive diseaseOFFSIDES
672PolymyositisOFFSIDES
673Post procedural nauseaOFFSIDES
674Postmenopausal bleedingOFFSIDES
675Procedural hypotensionOFFSIDES
676Protein total decreasedCanada Vigilance: 1Canada Vigilance
677Prothrombin level decreasedOFFSIDES
678Pruritus allergicOFFSIDES
679Psoas AbscessOFFSIDES
680Psychiatric symptomOFFSIDES
681Reaction gastrointestinalSIDER
682Renal cystOFFSIDES
683Respiratory Insufficiency7671986CTD
684Retinal Diseases

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CTD
685Seizures11149659CTD
686SeromaOFFSIDES
687Skeletal injuryOFFSIDES
688Skin IndurationOFFSIDES
689Skin hypertrophyOFFSIDES
690Soft Tissue InjuriesOFFSIDES
691Spinal fusion surgeryOFFSIDES
692Spinal rod insertionOFFSIDES
693Subcutaneous noduleOFFSIDES
694Supraventricular tachycardiaOFFSIDES
695Temperature intoleranceOFFSIDES
696TendinitisOFFSIDES
697TensionSIDER
698TonsillitisOFFSIDES
699Torsades de Pointes16615675CTD
700Toxoplasmosis5120183CTD
701TracheitisOFFSIDES
702Vasculitic rashOFFSIDES
703Vasculitis, Leukocytoclastic, Cutaneous17162415CTD
704Ventricular Fibrillation16142151CTD
705Viral labyrinthitisOFFSIDES
706Vision Disorders

View details

CTD
707Weight GainOFFSIDES
708Wound dehiscenceOFFSIDES
709bone marrow fibrosisOFFSIDES
710effusionOFFSIDES
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