MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Crohn Disease

(UMLS:C0010346)

Definition:: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
UMLS ID:: C0010346
MeSH ID:: D003424

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.205.731.500|C06.405.469.432.500

Synonym(s)

Crohn Disease

CD - Crohn's disease

CROHN DISEASE

CROHN'S DISEASE

Crohn

Crohn disease

Crohn's

Crohn's Disease

Crohn's disease

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Acetaminophen	21127120	CTD
2	Ampicillin	18319500	CTD
3	Azathioprine	View details 10833103 10923928 12003743 12269967 12924643 14505127 15626912 16397313 16431304 17262810 17304143 17404860 17729423 18431703 19652986 20593510	CTD
4	Aztreonam	18319500	CTD
5	BIRB 796	21328587	CTD
6	Budesonide	11417618	CTD
7	Chlordiazepoxide	18711101	CTD
8	Ciprofloxacin	12399240 18319500	CTD
9	Fusidic Acid	1420741	CTD
10	Hydrocortisone	21127120	CTD
11	Linezolid	18319500	CTD
12	Mercaptopurine	View details 14505127 18711101 19652986 25108385	CTD
13	Mesalamine	View details 7830805 9059966 9582560 9823562 10189017 10791141 11205659 11431204 11906377 11996772 12003743 12070416 12500420 12833232 16239842 17224428 17242922 17304143 18711101 18928745 18930179 19259075 19319380 20178728	CTD
14	Methotrexate	View details 10592889 16123897 16696812 19652986	CTD
15	Methylprednisolone	18833788	CTD
16	Metronidazole	View details 48003 198056 749126 1849313 2154078 2981752 6336861 7084615 15450780 18319500 21127120	CTD
17	Prednisolone	15450780	CTD
18	Prednisone	View details 10791141 11205659 11417618 12003743 16123897 18711101 19652986	CTD
19	Sulfasalazine	View details 33552 4146729 6127975 6133211 6146502 10394456 10791141 12587019 15450780 19319380	CTD
20	Thalidomide	View details 11339241 11345184 11788559 14508228 15694139 16078585 17269997	CTD
21	Thioguanine	15472529 18521912	CTD
22	clidinium	18711101	CTD
23	reviparin	1352765	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Dysentery	49.2%
2	Enteritis	49.2%
3	Enterocolitis	49.2%
4	Colitis	40.7%
5	Proctitis	40.7%
6	Esophagitis	39.3%
7	Gastritis	39.3%
8	Proctocolitis	38.9%
9	Duodenitis	38.7%
10	Ileitis	38.7%
11	Erosive Duodenitis	38.7%
12	Zollinger-Ellison syndrome	36.1%
13	Esophageal Diseases	33.3%
14	Stomach Diseases	33.3%
15	Appendicitis	32.7%
16	Cecal Diseases	32.6%
17	Colonic Diseases	32.6%
18	Ileal Diseases	32.6%
19	Intestinal Obstruction	32.6%
20	Intestinal Perforation	32.6%
21	Jejunal Diseases	32.6%
22	Pneumatosis Cystoides Intestinalis	32.6%
23	Rectal Diseases	32.6%
24	Cronkhite-Canada Syndrome	32.6%
25	Intestinal Polyposis	32.6%
26	Duodenal Obstruction	32.3%
27	Enterocolitis, Neutropenic	32.3%
28	Necrotizing Enterocolitis	32.3%
29	Duodenogastric Reflux	30.9%
30	Peptic Ulcer	30.9%
31	Colorectal Neoplasms	30.6%
32	Intestinal Neoplasms	29.5%
33	Pouchitis	28.8%
34	Gastrointestinal Neoplasms	27%
35	Mesenteric vascular insufficiency	27%
36	Intestinal Atresia	26.7%
37	Mesenteric Vascular Occlusion	26.7%
38	Intestinal Fistula	26.5%
39	Enterocutaneous Fistula	26.5%
40	Intestinal Diseases, Parasitic	25.9%
41	Enterocolitis, Pseudomembranous	25.8%
42	pseudomembranous colitis	25.8%
43	Dysentery, Bacillary	25.8%
44	Cecal Neoplasms	25.7%
45	Duodenal Neoplasms	25.7%
46	Gastrointestinal Hemorrhage	25%
47	Rectal Fistula	24.8%
48	Anal Fistula	24.8%
49	Tuberculosis, Gastrointestinal	24.6%
50	Stomach Neoplasms	23%
51	Colitis, Ischemic	23%
52	Colonic Pseudo-Obstruction	22%
53	Duodenal Ulcer	21.7%
54	Peptic Ulcer Perforation	21.7%
55	Gastric ulcer	21.7%
56	Colonic Diseases, Functional	21.5%
57	Fecal Incontinence	21.5%
58	Fecal Impaction	21.5%
59	Intussusception	21.5%
60	Megacolon	21.5%
61	Ileus	21.5%
62	Meconium ileus	21.5%
63	Biliary Tract Diseases	20.9%
64	Liver diseases	20.9%
65	Pancreatic Diseases	20.9%
66	Anus Neoplasms	19.8%
67	Sigmoid Neoplasms	19.8%
68	Esophageal Neoplasms	19.7%
69	Esophageal and Gastric Varices	19.7%
70	Esophageal Stenosis	19.6%
71	Gastric Dilatation	19.6%
72	Gastric outlet obstruction	19.6%
73	Appendiceal Neoplasms	19.1%
74	Colonic Neoplasms	19.1%
75	Rectal Neoplasms	19.1%
76	Esophageal Atresia	18.7%
77	Adenomatous Polyposis Coli	18.2%
78	Gastroenteritis	16.7%
79	Intestinal Diseases	16.7%
80	Hemorrhoids	16.5%
81	Afferent Loop Syndrome	16.3%
82	Celiac Disease	16.3%
83	Short Bowel Syndrome	16.3%
84	Sprue, Tropical	16.3%
85	Steatorrhea	16.3%
86	Rectocele	16.3%
87	Sprue	16.3%
88	Diverticulitis	16.1%
89	Rectal Prolapse	16.1%
90	Anal Fissure	16%
91	Intestinal Pseudo-Obstruction	16%
92	Irritable Bowel Syndrome	16%
93	Superior Mesenteric Artery Syndrome	16%
94	Neurogenic Bowel	16%
95	Anal Ulcer	16%
96	Digestive System Neoplasms	15.8%
97	Gastrointestinal Stromal Tumors	15.7%
98	Esophageal Perforation	15.5%
99	Barrett Esophagus	15%
100	Deglutition Disorders	15%
101	Achlorhydria	14.8%
102	Inflammatory Bowel Diseases	14.8%
103	Gastric Antral Vascular Ectasia	14.8%
104	Peptic Ulcer Hemorrhage	14.6%
105	Gastroparesis	14.6%
106	Liver neoplasms	13.5%
107	Giardiasis	13.4%
108	Pancreatic Fistula	13.4%
109	Diverticulum	13.2%
110	Diverticulosis	13.2%
111	Esophageal motility disorders	12.9%
112	Mallory-Weiss Syndrome	12.9%
113	Pyloric Stenosis	12.9%
114	Pruritus Ani	12.1%
115	Melena	11.9%
116	Hematemesis	11.7%
117	Peritoneal Neoplasms	11.2%
118	Bile Duct Diseases	11.1%
119	Cholelithiasis	11.1%
120	Chylous Ascites	11.1%
121	Fatty Liver	11.1%
122	Hepatitis	11.1%
123	Portal Hypertension	11.1%
124	Liver Cirrhosis	11.1%
125	Pancreatic Insufficiency	11.1%
126	Pancreatitis	11.1%
127	Pneumoperitoneum	11.1%
128	Focal Nodular Hyperplasia	11.1%
129	Hepatic Insufficiency	11.1%
130	Steatohepatitis	11.1%
131	Peutz-Jeghers Syndrome	10.9%
132	Lactose Intolerance	10.8%
133	Bile Duct Neoplasms	9.8%
134	gallbladder neoplasm	9.8%
135	Cholecystolithiasis	9.8%
136	Biliary cirrhosis	9.8%
137	Pancreatic Neoplasm	9.7%
138	Crohn Disease	9.7%
139	Dumping Syndrome	9.7%
140	Esophageal Achalasia	9.6%
141	Choledochal Cyst	9%
142	Liver Diseases, Parasitic	8.8%
143	Hepatic Veno-Occlusive Disease	8.5%
144	Pancreatic Cyst	8.5%
145	Peliosis Hepatis	8.5%
146	Hepatopulmonary Syndrome	8.5%
147	Anus, Imperforate	8.3%
148	Hemoperitoneum	8.3%
149	Hepatomegaly	8.3%
150	Mesenteric Panniculitis	8.3%
151	Panniculitis, Peritoneal	8.3%
152	Peritonitis	8.3%
153	Peritoneal Fibrosis	8.3%
154	Encapsulating Peritoneal Sclerosis	8.3%
155	Anorectal Malformations	8.3%
156	Cryptosporidiosis	8.3%
157	Biliary Fistula	8.3%
158	Gastric Fistula	8.3%
159	Hepatic Vein Thrombosis	8.2%
160	Liver Abscess	8.2%
161	Budd-Chiari Syndrome	8.2%
162	Choledocholithiasis	8.1%
163	Fatty Liver, Alcoholic	7.8%
164	Hepatitis, Alcoholic	7.8%
165	Liver Cirrhosis, Alcoholic	7.8%
166	Chemical and Drug Induced Liver Injury	6.8%
167	Hepatorenal Syndrome	6.6%
168	Cholangitis	6.5%
169	Cholecystitis	6.5%
170	Cholestasis	6.5%
171	Common Bile Duct Diseases	6.5%
172	Hepatitis, Chronic	6.5%
173	Liver Failure	6.5%
174	Pancreatitis, Chronic	6.5%
175	Hepatocellular Adenoma	6.5%
176	Non-alcoholic Fatty Liver Disease	6.5%
177	Chronic active hepatitis	6.5%
178	Laryngopharyngeal Reflux	6.2%
179	Cystic Fibrosis	5.7%
180	Liver Abscess, Amebic	5.7%
181	Liver Neoplasms, Experimental	5.7%
182	Porphyrias, Hepatic	5.6%
183	Congenital Hyperinsulinism	5.6%
184	Hepatitis, Animal	5.2%
185	Hepatitis, Viral, Human	5.2%
186	Liver Cirrhosis, Experimental	4.9%
187	Pancreatic Pseudocyst	4.9%
188	Pancreatitis, Alcoholic	4.9%
189	Carcinoma, Pancreatic Ductal	4.3%
190	Cholestasis, Extrahepatic	4.3%
191	Biliary Dyskinesia	4.3%
192	Cholangitis, Sclerosing	4.3%
193	Liver Failure, Acute	4.3%
194	Acalculous Cholecystitis	4.3%
195	End Stage Liver Disease	4.3%
196	Fascioliasis	4%
197	Echinococcosis, Hepatic	4%
198	Chemical and Drug Induced Liver Injury, Chronic	3.9%
199	Reye Syndrome	3.9%
200	Hepatitis B, Chronic	3.8%
201	Hepatitis C, Chronic	3.8%
202	CREST Syndrome	3.6%
203	Autoimmune hepatitis	3.3%
204	Nesidioblastosis	3.2%
205	Variegate Porphyria	3.2%
206	Acute intermittent porphyria	3.2%
207	Porphyria Cutanea Tarda	3.2%
208	Massive Hepatic Necrosis	3.2%
209	Emphysematous Cholecystitis	3.2%
210	Sphincter of Oddi Dysfunction	3.2%
211	insulinoma	3.2%
212	Gastrinoma	3.2%
213	Glucagonoma	3.2%
214	Vipoma	2.8%
215	Hepatitis, Viral, Animal	2.8%
216	Zellweger Syndrome	2.7%
217	Hepatitis E	2.7%
218	Hepatitis B	2.6%
219	Hepatitis C	2.6%
220	Hepatitis A	2.6%
221	Hepatic Encephalopathy	2.6%
222	Hepatolenticular Degeneration	2.5%
223	Rift Valley Fever	1.3%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120237