drospirenone and ethinyl estradiol combination
(JLQFVGYYVXALAG-CFEVTAHFSA-N)
Structure
- SMILES
- O=C1CC[C@]2(C(=C1)[C@@H]1C[C@@H]1[C@@H]1[C@@H]2CC[C@]2([C@H]1[C@@H]1C[C@@H]1[C@]12CCC(=O)O1)C)C.C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCc2c1ccc(c2)O
- Molecular Formula:
- C44H54O5
- Molecular Weight:
- 662.897
- Log P:
- 7.9185
- Hydrogen Bond Acceptor:
- 5
- Hydrogen Bond Donor:
- 2
- TPSA:
- 83.83
- CAS Number(s):
- 164017-31-6
Synonym(s)
1.
drospirenone and ethinyl estradiol combination
2.
YAZ combination
3.
Yasmin
4.
Yaz
5.
drospirenone, ethinyl estradiol drug combination
6.
yasminelle
External Link(s)
Adverse Drug Event(s)
| Name | Number of Reports | Reference(s) | Data Source | |
|---|---|---|---|---|
| 1 | Pain | FAERS: 178 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 2 | Pulmonary Embolism | FAERS: 109 Canada Vigilance: 60 | 19363241 | CTD Canada Vigilance US FAERS |
| 3 | Deep Vein Thrombosis | FAERS: 98 Canada Vigilance: 24 | Canada Vigilance US FAERS | |
| 4 | Emotional distress | FAERS: 90 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 5 | Metrorrhagia | FAERS: 65 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 6 | Nausea | FAERS: 64 Canada Vigilance: 11 | Canada Vigilance US FAERS | |
| 7 | Anxiety | FAERS: 61 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 8 | Drug dose omission | FAERS: 53 | US FAERS | |
| 9 | Headache | FAERS: 53 Canada Vigilance: 18 | Canada Vigilance US FAERS | |
| 10 | Product substitution issue | FAERS: 42 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 11 | General physical health deterioration | FAERS: 39 | US FAERS | |
| 12 | Vomiting | FAERS: 34 Canada Vigilance: 9 | Canada Vigilance US FAERS | |
| 13 | Thrombosis | FAERS: 30 Canada Vigilance: 11 | Canada Vigilance US FAERS | |
| 14 | Menorrhagia | FAERS: 29 | US FAERS | |
| 15 | Fatigue | FAERS: 27 Canada Vigilance: 13 | Canada Vigilance US FAERS | |
| 16 | Abdominal Pain | FAERS: 25 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 17 | Dizziness | FAERS: 25 Canada Vigilance: 10 | Canada Vigilance US FAERS | |
| 18 | Drug ineffective | FAERS: 25 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 19 | Malaise | FAERS: 24 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 20 | Cholelithiasis | FAERS: 23 Canada Vigilance: 20 | Canada Vigilance US FAERS | |
| 21 | Mood swings | FAERS: 23 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 22 | Acne | FAERS: 22 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 23 | Anhedonia | FAERS: 22 | US FAERS | |
| 24 | Inappropriate schedule of drug administration | FAERS: 22 | US FAERS | |
| 25 | Cerebrovascular accident | FAERS: 21 Canada Vigilance: 9 | Canada Vigilance US FAERS | |
| 26 | No adverse event | FAERS: 21 | US FAERS | |
| 27 | Chest Pain | FAERS: 17 Canada Vigilance: 9 | 19363241 | CTD Canada Vigilance US FAERS |
| 28 | Crying | FAERS: 17 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 29 | Feeling abnormal | FAERS: 17 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 30 | Abdominal discomfort | FAERS: 16 | US FAERS | |
| 31 | Alopecia | FAERS: 16 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 32 | Abnormal withdrawal bleeding | FAERS: 15 | US FAERS | |
| 33 | Palpitations | FAERS: 13 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 34 | Product use issue | FAERS: 13 | US FAERS | |
| 35 | Product quality issue | FAERS: 12 | US FAERS | |
| 36 | Adverse event | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 37 | Breast tenderness | FAERS: 11 | US FAERS | |
| 38 | Pregnancy on oral contraceptive | FAERS: 11 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 39 | Anger | FAERS: 9 | US FAERS | |
| 40 | Pulmonary thrombosis | FAERS: 9 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 41 | Back Pain | FAERS: 8 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 42 | Depressed mood | FAERS: 8 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 43 | Emotional disorder | FAERS: 8 | US FAERS | |
| 44 | Extra dose administered | FAERS: 8 | US FAERS | |
| 45 | Premenstrual syndrome | FAERS: 8 | 19363241 | CTD US FAERS |
| 46 | Syncope | FAERS: 8 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 47 | Cholecystitis | FAERS: 7 Canada Vigilance: 6 | Canada Vigilance US FAERS | |
| 48 | Constipation | FAERS: 7 | US FAERS | |
| 49 | Urticaria | FAERS: 7 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 50 | Asthenia | FAERS: 6 Canada Vigilance: 4 | Canada Vigilance US FAERS | |
| 51 | Drug administration error | FAERS: 6 | US FAERS | |
| 52 | Dyspepsia | FAERS: 6 | US FAERS | |
| 53 | Medication Error | FAERS: 6 | US FAERS | |
| 54 | Pelvic Pain | FAERS: 6 | US FAERS | |
| 55 | Activities of daily living impaired | FAERS: 5 | US FAERS | |
| 56 | Night sweats | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 57 | Product dose omission | FAERS: 5 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 58 | Weight decreased | FAERS: 5 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 59 | Amnesia | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 60 | Arthralgia | FAERS: 4 | US FAERS | |
| 61 | Bulimia Nervosa | FAERS: 4 | US FAERS | |
| 62 | Discomfort | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 63 | Hormone level abnormal | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 64 | Lethargy | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 65 | Ocular icterus | FAERS: 4 | US FAERS | |
| 66 | Personality Change | FAERS: 4 | US FAERS | |
| 67 | Pruritus | FAERS: 4 | US FAERS | |
| 68 | Tachycardia | FAERS: 4 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 69 | Visual Impairment | FAERS: 4 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 70 | Abasia | FAERS: 3 | US FAERS | |
| 71 | Blindness | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 72 | Cerebral Thrombosis | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 73 | Drug ineffective for unapproved indication | FAERS: 3 | US FAERS | |
| 74 | Eye pain | FAERS: 3 | US FAERS | |
| 75 | Flatulence | FAERS: 3 | US FAERS | |
| 76 | Gallbladder pain | FAERS: 3 | US FAERS | |
| 77 | Incorrect dose administered | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 78 | Incorrect product storage | FAERS: 3 | US FAERS | |
| 79 | Nervousness | FAERS: 3 | US FAERS | |
| 80 | Oropharyngeal pain | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 81 | Paranoia | FAERS: 3 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 82 | Peripheral swelling | FAERS: 3 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 83 | Pharmaceutical product complaint | FAERS: 3 | US FAERS | |
| 84 | Product blister packaging issue | FAERS: 3 | US FAERS | |
| 85 | Product storage error | FAERS: 3 | US FAERS | |
| 86 | Product use in unapproved indication | FAERS: 3 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 87 | Psychological Trauma | FAERS: 3 | US FAERS | |
| 88 | Pulmonary Infarction | FAERS: 3 | US FAERS | |
| 89 | Self-induced vomiting | FAERS: 3 | US FAERS | |
| 90 | Therapeutic response unexpected with drug substitution | FAERS: 3 | US FAERS | |
| 91 | Unevaluable event | FAERS: 3 | US FAERS | |
| 92 | Adnexa uteri pain | FAERS: 2 | US FAERS | |
| 93 | Anorexia | FAERS: 2 | US FAERS | |
| 94 | Biliary Colic | FAERS: 2 Canada Vigilance: 7 | Canada Vigilance US FAERS | |
| 95 | Biliary Dyskinesia | FAERS: 2 | US FAERS | |
| 96 | Bipolar Disorder | FAERS: 2 | US FAERS | |
| 97 | Blood cortisol increased | FAERS: 2 | US FAERS | |
| 98 | Blood potassium decreased | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 99 | Chest discomfort | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 100 | Chills | FAERS: 2 | US FAERS | |
| 101 | Cyanosis | FAERS: 2 | US FAERS | |
| 102 | Endodontic procedure | FAERS: 2 | US FAERS | |
| 103 | Expired product administered | FAERS: 2 | US FAERS | |
| 104 | Hunger | FAERS: 2 | US FAERS | |
| 105 | Hypersensitivity | FAERS: 2 | US FAERS | |
| 106 | Impaired work ability | FAERS: 2 | US FAERS | |
| 107 | Inappropriate schedule of product administration | FAERS: 2 | US FAERS | |
| 108 | Influenza | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 109 | Irritable Bowel Syndrome | FAERS: 2 | US FAERS | |
| 110 | Joint swelling | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 111 | Medical diet | FAERS: 2 | US FAERS | |
| 112 | Musculoskeletal chest pain | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 113 | Myalgia | FAERS: 2 | US FAERS | |
| 114 | Neck Pain | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 115 | Pancreatitis | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 116 | Pelvic venous thrombosis | FAERS: 2 Canada Vigilance: 5 | Canada Vigilance US FAERS | |
| 117 | Pneumonia | FAERS: 2 | US FAERS | |
| 118 | Product formulation issue | FAERS: 2 | US FAERS | |
| 119 | Somnolence | FAERS: 2 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 120 | Stress | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 121 | Tinnitus | FAERS: 2 | US FAERS | |
| 122 | Tremor | FAERS: 2 Canada Vigilance: 3 | Canada Vigilance US FAERS | |
| 123 | Urinary tract infection | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 124 | Vaginal Discharge | FAERS: 2 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 125 | Vitreous floaters | FAERS: 2 | US FAERS | |
| 126 | Abdominal adhesions | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 127 | Acute myocardial infarction | FAERS: 1 | US FAERS | |
| 128 | Allergy to chemicals | FAERS: 1 | US FAERS | |
| 129 | Alopecia Areata | FAERS: 1 | US FAERS | |
| 130 | Aneurysm | FAERS: 1 | US FAERS | |
| 131 | Angina Pectoris | FAERS: 1 | US FAERS | |
| 132 | Apathy | FAERS: 1 | US FAERS | |
| 133 | Apparent death | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 134 | Appendicitis | FAERS: 1 | US FAERS | |
| 135 | Arterial Injury | FAERS: 1 | US FAERS | |
| 136 | Axillary vein thrombosis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 137 | Blood aldosterone increased | FAERS: 1 | US FAERS | |
| 138 | Blood copper increased | FAERS: 1 | US FAERS | |
| 139 | Blood fibrinogen increased | FAERS: 1 | US FAERS | |
| 140 | Blood homocysteine increased | FAERS: 1 | US FAERS | |
| 141 | Blood iron decreased | FAERS: 1 | US FAERS | |
| 142 | Blood potassium abnormal | FAERS: 1 | US FAERS | |
| 143 | Blood potassium increased | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 144 | Blood prolactin increased | FAERS: 1 | US FAERS | |
| 145 | Blood triglycerides increased | FAERS: 1 | US FAERS | |
| 146 | Body temperature fluctuation | FAERS: 1 | US FAERS | |
| 147 | Cardiac ventricular thrombosis | FAERS: 1 | US FAERS | |
| 148 | Cardiomegaly | FAERS: 1 | US FAERS | |
| 149 | Cerebral Infarction | FAERS: 1 | US FAERS | |
| 150 | Cervical dysplasia | FAERS: 1 | US FAERS | |
| 151 | Chloasma | FAERS: 1 | US FAERS | |
| 152 | Cholecystitis infective | FAERS: 1 | US FAERS | |
| 153 | Chorea | FAERS: 1 | US FAERS | |
| 154 | Cyst | FAERS: 1 | US FAERS | |
| 155 | Depression suicidal | FAERS: 1 | US FAERS | |
| 156 | Dermatitis acneiform | FAERS: 1 | US FAERS | |
| 157 | Diabetes Mellitus | FAERS: 1 | US FAERS | |
| 158 | Diabetes mellitus inadequate control | FAERS: 1 | US FAERS | |
| 159 | Diabetic Ketoacidosis | FAERS: 1 | US FAERS | |
| 160 | Disseminated Intravascular Coagulation | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 161 | Drug dispensing error | FAERS: 1 | US FAERS | |
| 162 | Drug effect incomplete | FAERS: 1 | US FAERS | |
| 163 | Drug use for unknown indication | FAERS: 1 | US FAERS | |
| 164 | Dry skin | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 165 | Dysuria | FAERS: 1 | US FAERS | |
| 166 | Economic problem | FAERS: 1 | US FAERS | |
| 167 | Eczema | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 168 | Educational problem | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 169 | Embolism | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 170 | Erythema Nodosum | FAERS: 1 | US FAERS | |
| 171 | Erythema | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 172 | Eye complication associated with device | FAERS: 1 | US FAERS | |
| 173 | Feeling Cold | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 174 | Feeling jittery | FAERS: 1 | US FAERS | |
| 175 | Feeling of body temperature change | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 176 | Female sex hormone level abnormal | FAERS: 1 | US FAERS | |
| 177 | Fibrin D dimer increased | FAERS: 1 | US FAERS | |
| 178 | Fibroadenoma of breast | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 179 | Flushing | FAERS: 1 | US FAERS | |
| 180 | Heparin-induced thrombocytopenia | FAERS: 1 | US FAERS | |
| 181 | High density lipoprotein increased | FAERS: 1 | US FAERS | |
| 182 | Hypersomnia | FAERS: 1 | US FAERS | |
| 183 | Hypopituitarism | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 184 | Impaired gastric emptying | FAERS: 1 | US FAERS | |
| 185 | Incorrect drug administration duration | FAERS: 1 | US FAERS | |
| 186 | Intentional product misuse | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 187 | Intentional product use issue | FAERS: 1 | US FAERS | |
| 188 | Intercepted product selection error | FAERS: 1 | US FAERS | |
| 189 | Joint injury | FAERS: 1 | US FAERS | |
| 190 | Lactose Intolerance | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 191 | Lip swelling | FAERS: 1 | US FAERS | |
| 192 | Livedo Reticularis | FAERS: 1 | US FAERS | |
| 193 | Loss of personal independence in daily activities | FAERS: 1 Canada Vigilance: 2 | Canada Vigilance US FAERS | |
| 194 | Low density lipoprotein increased | FAERS: 1 | US FAERS | |
| 195 | Medical device complication | FAERS: 1 | US FAERS | |
| 196 | Medication monitoring error | FAERS: 1 | US FAERS | |
| 197 | Menopause | FAERS: 1 | US FAERS | |
| 198 | Mental impairment | FAERS: 1 | US FAERS | |
| 199 | Middle insomnia | FAERS: 1 | US FAERS | |
| 200 | Multi-organ disorder | FAERS: 1 | US FAERS | |
| 201 | Myocardial Infarction | FAERS: 1 | 17636199 | CTD US FAERS |
| 202 | Nephrolithiasis | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 203 | Pallor | FAERS: 1 | US FAERS | |
| 204 | Patient dissatisfaction with treatment | FAERS: 1 | US FAERS | |
| 205 | Pelvic discomfort | FAERS: 1 | US FAERS | |
| 206 | Photophobia | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 207 | Poor peripheral circulation | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 208 | Porphyria non-acute | FAERS: 1 | US FAERS | |
| 209 | Pre-existing condition improved | FAERS: 1 | US FAERS | |
| 210 | Pregnancy on contraceptive | FAERS: 1 | US FAERS | |
| 211 | Pregnancy | FAERS: 1 | US FAERS | |
| 212 | Premature Menopause | FAERS: 1 | US FAERS | |
| 213 | Presyncope | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 214 | Product administration error | FAERS: 1 | US FAERS | |
| 215 | Product commingling | FAERS: 1 | US FAERS | |
| 216 | Product package associated injury | FAERS: 1 | US FAERS | |
| 217 | Product packaging quantity issue | FAERS: 1 | US FAERS | |
| 218 | Product prescribing issue | FAERS: 1 | US FAERS | |
| 219 | Product supply issue | FAERS: 1 | US FAERS | |
| 220 | Pulmonary congestion | FAERS: 1 | US FAERS | |
| 221 | Secretion discharge | FAERS: 1 | US FAERS | |
| 222 | Shock | FAERS: 1 | US FAERS | |
| 223 | Sinus Tachycardia | FAERS: 1 | US FAERS | |
| 224 | Skin lesion | FAERS: 1 | US FAERS | |
| 225 | Stevens-Johnson Syndrome | FAERS: 1 | US FAERS | |
| 226 | Sudden Visual Loss | FAERS: 1 | US FAERS | |
| 227 | Sudden death | FAERS: 1 | US FAERS | |
| 228 | Therapeutic response unexpected | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 229 | Therapy cessation | FAERS: 1 | US FAERS | |
| 230 | Throat irritation | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 231 | Thrombotic stroke | FAERS: 1 | US FAERS | |
| 232 | Tooth Infection | FAERS: 1 | US FAERS | |
| 233 | Venous thrombosis limb | FAERS: 1 Canada Vigilance: 1 | Canada Vigilance US FAERS | |
| 234 | Violence-related symptom | FAERS: 1 | US FAERS | |
| 235 | Vulvovaginal dryness | FAERS: 1 | US FAERS | |
| 236 | Vulvovaginal mycotic infection | FAERS: 1 | US FAERS | |
| 237 | skin abrasion | FAERS: 1 | US FAERS | |
| 238 | Acne Vulgaris | 19363241 | CTD | |
| 239 | Acute kidney injury | Canada Vigilance: 1 | Canada Vigilance | |
| 240 | Alanine Aminotransferase Increased | Canada Vigilance: 1 | Canada Vigilance | |
| 241 | Anaphylactic shock | Canada Vigilance: 2 | Canada Vigilance | |
| 242 | Apparent life threatening event | Canada Vigilance: 1 | Canada Vigilance | |
| 243 | Aspartate Aminotransferase Increased | Canada Vigilance: 1 | Canada Vigilance | |
| 244 | Astigmatism | Canada Vigilance: 1 | Canada Vigilance | |
| 245 | Blood glucose increased | Canada Vigilance: 1 | Canada Vigilance | |
| 246 | Burning sensation | Canada Vigilance: 2 | Canada Vigilance | |
| 247 | Cardiac Arrest | Canada Vigilance: 2 | Canada Vigilance | |
| 248 | Deafness | Canada Vigilance: 1 | Canada Vigilance | |
| 249 | Dehydration | Canada Vigilance: 1 | Canada Vigilance | |
| 250 | Disorientation | Canada Vigilance: 1 | Canada Vigilance | |
| 251 | Drug withdrawal syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 252 | Dysmenorrhea | 20931801 | CTD | |
| 253 | Dyspnea | 19363241 | CTD | |
| 254 | Ear discomfort | Canada Vigilance: 1 | Canada Vigilance | |
| 255 | Electrocardiogram abnormal | Canada Vigilance: 1 | Canada Vigilance | |
| 256 | Endometriosis ablation | Canada Vigilance: 1 | Canada Vigilance | |
| 257 | Epistaxis | Canada Vigilance: 2 | Canada Vigilance | |
| 258 | Facial paralysis | Canada Vigilance: 1 | Canada Vigilance | |
| 259 | Food Allergy | Canada Vigilance: 1 | Canada Vigilance | |
| 260 | Food craving | Canada Vigilance: 1 | Canada Vigilance | |
| 261 | Gait inability | Canada Vigilance: 1 | Canada Vigilance | |
| 262 | Hemiplegia | Canada Vigilance: 1 | Canada Vigilance | |
| 263 | Hepatic vein stenosis | Canada Vigilance: 1 | Canada Vigilance | |
| 264 | Hypokinesia | Canada Vigilance: 1 | Canada Vigilance | |
| 265 | Hypotension | Canada Vigilance: 1 | Canada Vigilance | |
| 266 | Idiosyncratic drug reaction | Canada Vigilance: 1 | Canada Vigilance | |
| 267 | Insulin Resistance | Canada Vigilance: 2 | Canada Vigilance | |
| 268 | Libido disorder | Canada Vigilance: 2 | Canada Vigilance | |
| 269 | Lip exfoliation | Canada Vigilance: 1 | Canada Vigilance | |
| 270 | Lymphadenopathy | Canada Vigilance: 1 | Canada Vigilance | |
| 271 | Memory impairment | Canada Vigilance: 3 | Canada Vigilance | |
| 272 | Migraine with Aura | Canada Vigilance: 5 | Canada Vigilance | |
| 273 | Multiple Sclerosis | Canada Vigilance: 1 | Canada Vigilance | |
| 274 | Nasopharyngitis | Canada Vigilance: 1 | Canada Vigilance | |
| 275 | Obsessive-Compulsive Disorder | Canada Vigilance: 1 | Canada Vigilance | |
| 276 | Oral pruritus | Canada Vigilance: 1 | Canada Vigilance | |
| 277 | Pancreatic enzymes increased | Canada Vigilance: 1 | Canada Vigilance | |
| 278 | Pharyngeal swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 279 | Precancerous cells present | Canada Vigilance: 2 | Canada Vigilance | |
| 280 | Renal pain | Canada Vigilance: 1 | Canada Vigilance | |
| 281 | Respiratory arrest | Canada Vigilance: 1 | Canada Vigilance | |
| 282 | Rhinalgia | Canada Vigilance: 1 | Canada Vigilance | |
| 283 | Sciatica | Canada Vigilance: 1 | Canada Vigilance | |
| 284 | Serotonin Syndrome | Canada Vigilance: 1 | Canada Vigilance | |
| 285 | Somatic symptom disorder | Canada Vigilance: 1 | Canada Vigilance | |
| 286 | Swelling | Canada Vigilance: 1 | Canada Vigilance | |
| 287 | Tachyarrhythmia | Canada Vigilance: 1 | Canada Vigilance | |
| 288 | Thirst | Canada Vigilance: 1 | Canada Vigilance | |
| 289 | Thromboembolism | 17766604 | CTD | |
| 290 | Vascular procedure complication | Canada Vigilance: 1 | Canada Vigilance | |
| 291 | Venous Thrombosis | Canada Vigilance: 1 | 19363241 | CTD Canada Vigilance |
| 292 | Vulvovaginal pain | Canada Vigilance: 1 | Canada Vigilance | |
| 293 | jaundice | Canada Vigilance: 1 | Canada Vigilance |
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