MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypernatremia

(UMLS:C0020488)

Definition:: Excessive amount of sodium in the blood. (Dorland, 27th ed)
UMLS ID:: C0020488
MeSH ID:: D006955

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.452.950.452

Synonym(s)

Hypernatremia

HYPERNATRAEMIA

HYPERNATREMIA

High blood sodium levels

Hypernatraemia

Hypernatraemia, NOS

Hypernatremia, NOS

Na excess

Na overload

10.

Sodium overload

11.

Sodium retention

12.

excess sodium

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Cellulose	29458016	CTD
2	Colchicine	10383025	CTD
3	Fluorides	5033780	CTD
4	Indomethacin	3921582	CTD
5	Lithium	3921582 12870877	CTD
6	Mannitol	20804114	CTD
7	Methoxyflurane	View details 4722675 4818422 4853325 5007641 5033780 5725736	CTD
8	Nandrolone Decanoate	15849280	CTD
9	Oxymetholone	15849280	CTD
10	Penicillin G	5722316	CTD
11	Promethazine	10548178	CTD
12	Spironolactone	10100081	CTD
13	Stanozolol	15849280	CTD
14	Testosterone Propionate	17327368	CTD
15	boldenone	15849280	CTD
16	calcipotriene	14999528	CTD
17	liposomal amphotericin B	12562731	CTD
18	sodium thiosulfate	16086410	CTD
19	testosterone 17-phenylpropionate	15849280	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Hyperkalemia	46.7%
2	Hypokalemia	46.7%
3	Hyponatremia	46.7%
4	Hypercalcemia	44.4%
5	Hypocalcemia	44.4%
6	Milk-Alkali Syndrome	44.4%
7	Dehydration	31.8%
8	Water Intoxication	31.8%
9	Acid-Base Imbalance	31%
10	Calcium Metabolism Disorders	31%
11	Iron Metabolism Disorders	31%
12	Phosphorus Metabolism Disorders	31%
13	Lipid Metabolism Disorders	31%
14	Mitochondrial Diseases	31%
15	Glucose Metabolism Disorders	31%
16	Wasting Syndrome	27.9%
17	Osteopenia	20.9%
18	Brain Diseases, Metabolic	20.5%
19	Acidosis	20%
20	Alkalosis	20%
21	Amyloidosis	20%
22	Calcinosis	20%
23	Hyperglycemia	20%
24	Hyperinsulinism	20%
25	Hypoglycemia	20%
26	Lipodystrophy	20%
27	Xanthomatosis	20%
28	Hypophosphatemia	20%
29	Metabolic acidosis	20%
30	Dyslipidemias	20%
31	Iron Overload	20%
32	Xanthoma	20%
33	Nutrition Disorders	18.5%
34	Pseudohypoparathyroidism	18.1%
35	Rickets	17.3%
36	Brain Diseases, Metabolic, Inborn	15.9%
37	Leigh Disease	15.2%
38	Hyperhomocysteinemia	15.1%
39	Acidosis, Lactic	14.8%
40	Calciphylaxis	14.8%
41	Hemosiderosis	14.8%
42	Ketosis	14.8%
43	Ketonuria	14.8%
44	Ketoacidosis	14.8%
45	Ketonemia	14.8%
46	Vascular calcification	14.8%
47	Hypolipoproteinemias	14.6%
48	Hyperlipoproteinemia Type IV	14.5%
49	Hyperlipoproteinemia Type V	14.5%
50	Diabetes Mellitus	14.3%
51	Carbamoyl-Phosphate Synthase I Deficiency Disease	13.8%
52	Lactose Intolerance	13.7%
53	Lipomatosis	13.6%
54	Werner Syndrome	13.6%
55	Diabetic Ketoacidosis	13.5%
56	Hyperlipidemia, Familial Combined	13.4%
57	Achlorhydria	13.3%
58	Amino Acid Metabolism, Inborn Errors	13.3%
59	Bloom Syndrome	13.3%
60	Carbohydrate Metabolism, Inborn Errors	13.3%
61	Metal Metabolism, Inborn Errors	13.3%
62	Osteoporosis	13.3%
63	Progeria	13.3%
64	Lysosomal Storage Diseases	13.3%
65	Bone Demineralization, Pathologic	13.3%
66	Cytochrome-c Oxidase Deficiency	13.3%
67	Peroxisomal Disorders	13.3%
68	Post-Traumatic Osteoporosis	13.3%
69	Celiac Disease	13.2%
70	Sprue, Tropical	13.2%
71	Steatorrhea	13.2%
72	Sprue	13.2%
73	Osteomalacia	13%
74	Hyperlipoproteinemia Type III	12.7%
75	Smith-Lemli-Opitz Syndrome	12.6%
76	Galactosemias	12.5%
77	Urea Cycle Disorders, Inborn	12.5%
78	Tyrosinemias	12.5%
79	Hypercholesterolemia	12.2%
80	Hyperlipoproteinemias	12.2%
81	Hypertriglyceridemia	12.2%
82	Congenital Hyperinsulinism	12.2%
83	Hypoalphalipoproteinemias	12%
84	Familial Hypophosphatemic Rickets	11.5%
85	Mitochondrial Encephalomyopathies	11.5%
86	Gaucher Disease	10.9%
87	Hyperphosphaturia	10.9%
88	Glycogen storage disease type II	10.6%
89	Homocystinuria	10.4%
90	Child Nutrition Disorders	10.3%
91	Hypervitaminosis A	10.3%
92	Infant Nutrition Disorders	10.3%
93	Malnutrition	10.3%
94	Mitochondrial Myopathies	10.2%
95	Myelinolysis, Central Pontine	10.1%
96	Glycosuria	9.9%
97	Reye Syndrome	9.9%
98	Acidosis, Respiratory	9.9%
99	Adiposis Dolorosa	9.9%
100	Alkalosis, Respiratory	9.9%
101	Hepatic Encephalopathy	9.8%
102	Tay-Sachs Disease	9.8%
103	Nesidioblastosis	9.8%
104	Alkaptonuria	9.8%
105	Glycogen Storage Disease	9.8%
106	Hypophosphatasia	9.8%
107	Insulin Resistance	9.8%
108	Osteoporosis, Postmenopausal	9.8%
109	Propionic acidemia	9.8%
110	Dihydropyrimidine Dehydrogenase Deficiency	9.8%
111	Cystinosis	9.8%
112	Amyloid Neuropathies, Familial	9.8%
113	Renal tubular acidosis	9.7%
114	Niemann-Pick Disease, Type C	9.3%
115	Neuronal Ceroid-Lipofuscinoses	9%
116	HIV Wasting Syndrome	8.8%
117	Fabry Disease	8.5%
118	HIV-Associated Lipodystrophy Syndrome	8.4%
119	MELAS Syndrome	8.2%
120	Renal Osteodystrophy	8.2%
121	Renal rickets	8.2%
122	Porphyrias, Hepatic	8.1%
123	Glycogen Storage Disease Type I	8.1%
124	Glycogen Storage Disease Type V	8.1%
125	Zellweger Syndrome	8%
126	Mucopolysaccharidosis III	8%
127	Adrenoleukodystrophy	8%
128	Necrobiosis Lipoidica Diabeticorum	7.9%
129	Menkes Kinky Hair Syndrome	7.9%
130	Fanconi Anemia	7.8%
131	Wernicke Encephalopathy	7.7%
132	Gestational Diabetes	7.7%
133	Latent Autoimmune Diabetes in Adults	7.7%
134	Diabetes Mellitus, Experimental	7.6%
135	Hepatolenticular Degeneration	7.4%
136	Nephrocalcinosis	7.4%
137	Tetany	7.4%
138	Refsum Disease	7.3%
139	Glycosuria, Renal	7.3%
140	Cerebral Amyloid Angiopathy	7.2%
141	Deficiency Diseases	6.7%
142	Starvation	6.7%
143	Refeeding Syndrome	6.7%
144	Friedreich Ataxia	6.5%
145	Familial Periodic Paralysis	6%
146	Primary amyloidosis	6%
147	Variegate Porphyria	5.9%
148	Acute intermittent porphyria	5.9%
149	Porphyria Cutanea Tarda	5.9%
150	Renal Aminoacidurias	5.8%
151	Fanconi Syndrome	5.8%
152	Pseudohypoaldosteronism	5.8%
153	Liddle Syndrome	5.8%
154	Kernicterus	5.7%
155	Kearns-Sayre syndrome	5.7%
156	Cockayne Syndrome	5.7%
157	Canavan Disease	5.4%
158	Alexander Disease	5.4%
159	Sjogren-Larsson Syndrome	5.4%
160	Mucopolysaccharidosis II	5.3%
161	Ataxia Telangiectasia	5.1%
162	Gout	5%
163	Amyotrophic Lateral Sclerosis	5%
164	Kwashiorkor	4.9%
165	Magnesium Deficiency	4.9%
166	Potassium Deficiency	4.9%
167	Protein Deficiency	4.9%
168	Avitaminosis	4.9%
169	Optic Atrophy, Hereditary, Leber	4.9%
170	Antley-Bixler Syndrome Phenotype	4.9%
171	Hypokalemic periodic paralysis	4.9%
172	Frontotemporal dementia	4.8%
173	Cystinuria	4.8%
174	Xeroderma Pigmentosum	4.5%
175	CREST Syndrome	4.2%
176	Ascorbic Acid Deficiency	4.1%
177	Vitamin A Deficiency	4.1%
178	Vitamin D Deficiency	4.1%
179	Vitamin E Deficiency	4.1%
180	Marasmus	4.1%
181	Arthritis, Gouty	4.1%
182	Albinism	3.7%
183	Folic Acid Deficiency	3.6%
184	Pellagra	3.6%
185	Thiamine Deficiency	3.6%
186	Vitamin B 12 Deficiency	3.6%
187	Vitamin B 6 Deficiency	3.6%
188	Pyridoxine Deficiency	3.6%
189	Beriberi	3.4%
190	Ichthyosis, X-Linked	3%
191	Obesity	2.6%
192	Obesity, Abdominal	2.4%
193	Anemia, Pernicious	2.3%
194	Vitamin K Deficiency	2.1%
195	Pediatric Obesity	1.9%
196	Scurvy	1.8%
197	Prader-Willi Syndrome	1.6%
198	Subacute Combined Degeneration	1.2%

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