MetaADEDB 2.0 @ LMMD
Desogestrel
(MXBCYQUALCBQIJ-RYVPXURESA-N)
Structure
SMILES
CC[C@]12CC(=C)[C@H]3[C@H]([C@@H]1CC[C@@]2(O)C#C)CCC1=CCCC[C@H]31.C#C[C@]1(O)CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCc2c1ccc(c2)O
Molecular Formula:
C42H54O3
Molecular Weight:
606.876
Log P:
8.4823
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
3
TPSA:
60.69
CAS Number(s):
71138-35-7
Synonym(s)
1.
Desogestrel
2.
13-Ethyl-11-methylene-18,19-dinor-17 alpha-pregn-4-en-20-yn-17-ol
3.
Cerazette
4.
Marvelon
5.
Org-2969
6.
13 Ethyl 11 methylene 18,19 dinor 17 alpha pregn 4 en 20 yn 17 ol
7.
Org 2969
8.
Org2969
9.
alpha-pregn-4-en-20-yn-17-ol, 13-Ethyl-11-methylene-18,19-dinor-17
External Link(s)
MeSHD017135
PubChem Compound62957
CHEMBLCHEMBL1697756
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Pulmonary EmbolismFAERS: 106
Canada Vigilance: 3
Canada Vigilance
US FAERS
2Maternal exposure before pregnancyFAERS: 47US FAERS
3Inappropriate schedule of drug administrationFAERS: 46US FAERS
4NauseaFAERS: 39US FAERS
5VomitingFAERS: 39US FAERS
6HeadacheFAERS: 33US FAERS
7Deep Vein ThrombosisFAERS: 32US FAERS
8MetrorrhagiaFAERS: 30US FAERS
9Drug dose omissionFAERS: 29US FAERS
10ThrombosisFAERS: 29US FAERS
11DizzinessFAERS: 27
Canada Vigilance: 1
Canada Vigilance
US FAERS
12Drug administration errorFAERS: 20US FAERS
13Pharmaceutical product complaintFAERS: 19OFFSIDES
US FAERS
14Pregnancy on oral contraceptiveFAERS: 19
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
15Product use issueFAERS: 17US FAERS
16Abdominal PainFAERS: 16
Canada Vigilance: 2
Canada Vigilance
US FAERS
17Abnormal withdrawal bleedingFAERS: 16US FAERS
18MenorrhagiaFAERS: 14US FAERS
19PainFAERS: 14
Canada Vigilance: 1
Canada Vigilance
US FAERS
20AlopeciaFAERS: 12US FAERS
21Back PainFAERS: 12US FAERS
22FatigueFAERS: 12US FAERS
23MalaiseFAERS: 12US FAERS
24Memory impairmentFAERS: 12US FAERS
25Product use in unapproved indicationFAERS: 12US FAERS
26PalpitationsFAERS: 11US FAERS
27Pulmonary InfarctionFAERS: 11US FAERS
28AnxietyFAERS: 10US FAERS
29AstheniaFAERS: 10US FAERS
30Cardiac ArrestFAERS: 10US FAERS
31Adverse eventFAERS: 9US FAERS
32Cerebrovascular accidentFAERS: 9US FAERS
33Maternal exposure during pregnancyFAERS: 9US FAERS
34Medication ErrorFAERS: 9US FAERS
35Cerebral InfarctionFAERS: 8US FAERS
36EmbolismFAERS: 7US FAERS
37Urinary tract infectionFAERS: 7
Canada Vigilance: 1
Canada Vigilance
US FAERS
38Acute myocardial infarctionFAERS: 6US FAERS
39AphasiaFAERS: 6US FAERS
40Chest PainFAERS: 6
Canada Vigilance: 1
Canada Vigilance
US FAERS
41CholelithiasisFAERS: 6US FAERS
42Feeling abnormalFAERS: 6US FAERS
43HypersensitivityFAERS: 6US FAERS
44HypotensionFAERS: 6US FAERS
45Neck PainFAERS: 6US FAERS
46NephrolithiasisFAERS: 6US FAERS
47Product quality issueFAERS: 6US FAERS
48Therapeutic response unexpectedFAERS: 6US FAERS
49AppendicitisFAERS: 5US FAERS
50BronchitisFAERS: 5US FAERS
51Complication of deliveryFAERS: 5US FAERS
52EnteritisFAERS: 5US FAERS
53HemiparesisFAERS: 5OFFSIDES
US FAERS
54HypothyroidismFAERS: 5US FAERS
55Peripheral swellingFAERS: 5US FAERS
56PneumoniaFAERS: 5US FAERS
57PruritusFAERS: 5US FAERS
58Pulmonary thrombosisFAERS: 5US FAERS
59StressFAERS: 5US FAERS
60SyncopeFAERS: 5US FAERS
61Thoracic Outlet SyndromeFAERS: 5US FAERS
62TinnitusFAERS: 5OFFSIDES
US FAERS
63Abdominal discomfortFAERS: 4OFFSIDES
US FAERS
64AcneFAERS: 4US FAERS
65ArthralgiaFAERS: 4US FAERS
66Cerebral ThrombosisFAERS: 4US FAERS
67Drug exposure during pregnancyFAERS: 4US FAERS
68Drug ineffectiveFAERS: 4
Canada Vigilance: 2
Canada Vigilance
US FAERS
69Drug prescribing errorFAERS: 4OFFSIDES
US FAERS
70DyspepsiaFAERS: 4US FAERS
71EndometriosisFAERS: 4US FAERS
72EpilepsyFAERS: 4US FAERS
73Fibrin D dimer increasedFAERS: 4US FAERS
74Joint injuryFAERS: 4US FAERS
75LymphadenitisFAERS: 4US FAERS
76Mood swingsFAERS: 4US FAERS
77PancreatitisFAERS: 4US FAERS
78PleurisyFAERS: 4OFFSIDES
US FAERS
79PregnancyFAERS: 4US FAERS
80Product substitution issueFAERS: 4US FAERS
81Pulmonary artery thrombosisFAERS: 4OFFSIDES
US FAERS
82TachycardiaFAERS: 4US FAERS
83UrticariaFAERS: 4US FAERS
84ArthritisFAERS: 3US FAERS
85BlindnessFAERS: 3US FAERS
86Blood glucose increasedFAERS: 3US FAERS
87Brain HypoxiaFAERS: 3US FAERS
88Chest discomfortFAERS: 3US FAERS
89Cold sweatFAERS: 3OFFSIDES
US FAERS
90DysarthriaFAERS: 3US FAERS
91Ear discomfortFAERS: 3US FAERS
92ErythemaFAERS: 3US FAERS
93Facial ParesisFAERS: 3US FAERS
94HemiplegiaFAERS: 3OFFSIDES
US FAERS
95HypersomniaFAERS: 3US FAERS
96HyperthyroidismFAERS: 3US FAERS
97Incorrect dose administeredFAERS: 3OFFSIDES
US FAERS
98Incorrect drug administration durationFAERS: 3US FAERS
99InflammationFAERS: 3US FAERS
100MenopauseFAERS: 3US FAERS
101Musculoskeletal PainFAERS: 3US FAERS
102Musculoskeletal chest painFAERS: 3OFFSIDES
US FAERS
103OverdoseFAERS: 3OFFSIDES
US FAERS
104Pelvic PainFAERS: 3US FAERS
105Peripheral artery thrombosisFAERS: 3US FAERS
106Respiratory arrestFAERS: 3US FAERS
107RetchingFAERS: 3US FAERS
108SepsisFAERS: 3US FAERS
109Therapeutic response unexpected with drug substitutionFAERS: 3OFFSIDES
US FAERS
110Thyroid NeoplasmFAERS: 3US FAERS
111TremorFAERS: 3US FAERS
112Vaginal DischargeFAERS: 3US FAERS
113Venous ThrombosisFAERS: 3

View details

CTD
US FAERS
114Venous thrombosis limbFAERS: 3OFFSIDES
US FAERS
115Visual ImpairmentFAERS: 3US FAERS
116AbasiaFAERS: 2US FAERS
117Accidental overdoseFAERS: 2US FAERS
118AmnesiaFAERS: 2US FAERS
119Amylase increasedFAERS: 2US FAERS
120AneurysmFAERS: 2US FAERS
121Angina PectorisFAERS: 2US FAERS
122Arterial thrombosisFAERS: 2US FAERS
123Breast hyperplasiaFAERS: 2US FAERS
124Breast tendernessFAERS: 2US FAERS
125Capillary FragilityFAERS: 2US FAERS
126Circumstance or information capable of leading to medication errorFAERS: 2US FAERS
127ConstipationFAERS: 2US FAERS
128CyanosisFAERS: 2OFFSIDES
US FAERS
129CystitisFAERS: 2US FAERS
130DehydrationFAERS: 2US FAERS
131Diabetes MellitusFAERS: 2US FAERS
132DiscomfortFAERS: 2US FAERS
133Drug dispensing errorFAERS: 2US FAERS
134Drug ineffective for unapproved indicationFAERS: 2US FAERS
135Ectopic PregnancyFAERS: 2US FAERS
136EpistaxisFAERS: 2US FAERS
137Expired product administeredFAERS: 2US FAERS
138Eye painFAERS: 2US FAERS
139GastritisFAERS: 2US FAERS
140Head discomfortFAERS: 2US FAERS
141Hypertensive crisisFAERS: 2US FAERS
142Impaired work abilityFAERS: 2US FAERS
143Incorrect product storageFAERS: 2US FAERS
144InfectionFAERS: 2US FAERS
145InfertilityFAERS: 2US FAERS
146Intracranial AneurysmFAERS: 2US FAERS
147Limb discomfortFAERS: 2US FAERS
148Limb operationFAERS: 2US FAERS
149Lip swellingFAERS: 2US FAERS
150Multiple SclerosisFAERS: 2US FAERS
151Myocardial InfarctionFAERS: 2US FAERS
152Ocular vasculitisFAERS: 2US FAERS
153ParesisFAERS: 2US FAERS
154PetechiaeFAERS: 2US FAERS
155PharyngitisFAERS: 2US FAERS
156PhotophobiaFAERS: 2US FAERS
157Premenstrual syndromeFAERS: 2US FAERS
158Product packaging issueFAERS: 2US FAERS
159ProlactinomaFAERS: 2OFFSIDES
US FAERS
160PurpuraFAERS: 2US FAERS
161PyelonephritisFAERS: 2US FAERS
162Retinal Artery OcclusionFAERS: 2US FAERS
163RhinitisFAERS: 2US FAERS
164Sickle Cell TraitFAERS: 2US FAERS
165Sinus TachycardiaFAERS: 2US FAERS
166Sjogren's SyndromeFAERS: 2US FAERS
167SomnolenceFAERS: 2US FAERS
168Supraventricular tachycardiaFAERS: 2OFFSIDES
US FAERS
169SwellingFAERS: 2US FAERS
170Throat irritationFAERS: 2US FAERS
171VertigoFAERS: 2US FAERS
172Viral pericarditisFAERS: 2US FAERS
173Visual disturbanceFAERS: 2OFFSIDES
US FAERS
174Vulvovaginal mycotic infectionFAERS: 2US FAERS
175Weight decreasedFAERS: 2US FAERS
176Wrong drug administeredFAERS: 2US FAERS
177Abortion induced completeFAERS: 1US FAERS
178Activated Protein C ResistanceFAERS: 1US FAERS
179Activated partial thromboplastin time shortenedFAERS: 1US FAERS
180AgoraphobiaFAERS: 1US FAERS
181Allergic pharyngitisFAERS: 1US FAERS
182Allergic reaction to excipientFAERS: 1US FAERS
183Altered state of consciousnessFAERS: 1US FAERS
184AmaurosisFAERS: 1US FAERS
185Amniotic fluid volume decreasedFAERS: 1US FAERS
186Anal FistulaFAERS: 1US FAERS
187Androgens increasedFAERS: 1US FAERS
188AnhedoniaFAERS: 1US FAERS
189Ankle FractureFAERS: 1US FAERS
190Anorectal operationFAERS: 1US FAERS
191AnorexiaFAERS: 1US FAERS
192Antidepressant therapyFAERS: 1US FAERS
193Antiphospholipid AntibodiesFAERS: 1US FAERS
194Antithrombin III decreasedFAERS: 1US FAERS
195ArteriosclerosisFAERS: 1US FAERS
196Arteriovenous fistulaFAERS: 1US FAERS
197AsthmaFAERS: 1US FAERS
198Autoimmune thyroiditisFAERS: 1US FAERS
199Axillary vein thrombosisFAERS: 1OFFSIDES
US FAERS
200Benign neoplasm of thyroid glandFAERS: 1US FAERS
201Blighted ovumFAERS: 1US FAERS
202Blood creatine phosphokinase increasedFAERS: 1US FAERS
203Blood fibrinogen increasedFAERS: 1US FAERS
204Blood follicle stimulating hormone decreasedFAERS: 1US FAERS
205Blood human chorionic gonadotropin abnormalFAERS: 1US FAERS
206Blood iron decreasedFAERS: 1US FAERS
207Blood potassium decreasedFAERS: 1US FAERS
208Blood potassium increasedFAERS: 1US FAERS
209BradycardiaFAERS: 1US FAERS
210BradyphreniaFAERS: 1US FAERS
211Brain DeathFAERS: 1US FAERS
212Breast cancer stage IIFAERS: 1US FAERS
213Budd-Chiari SyndromeFAERS: 1US FAERS
214Burning sensationFAERS: 1US FAERS
215CandidiasisFAERS: 1US FAERS
216Carotid artery occlusionFAERS: 1US FAERS
217Cerebellar infarctionFAERS: 1US FAERS
218ChillsFAERS: 1US FAERS
219ChloasmaFAERS: 1US FAERS
220ChokingFAERS: 1US FAERS
221CholelithotomyFAERS: 1US FAERS
222ChoreaFAERS: 1US FAERS
223Coagulation factor VIII level increasedFAERS: 1US FAERS
224Coagulation factor XI level decreasedFAERS: 1US FAERS
225Coital bleedingFAERS: 1US FAERS
226Colonoscopy abnormalFAERS: 1US FAERS
227Coronary Artery DiseaseFAERS: 1US FAERS
228CryingFAERS: 1US FAERS
229Cyst removalFAERS: 1US FAERS
230Decidual castFAERS: 1US FAERS
231Delayed deliveryFAERS: 1US FAERS
232Dental Restoration FailureFAERS: 1US FAERS
233DiplopiaFAERS: 1US FAERS
234Disease ProgressionFAERS: 1US FAERS
235Disease complicationFAERS: 1US FAERS
236DisorientationFAERS: 1US FAERS
237Drug abuserFAERS: 1US FAERS
238Drug effect incompleteFAERS: 1US FAERS
239Drug effective for unapproved indicationFAERS: 1US FAERS
240Dust inhalation pneumopathyFAERS: 1US FAERS
241DysbacteriosisFAERS: 1US FAERS
242DysgeusiaFAERS: 1US FAERS
243DysphasiaFAERS: 1US FAERS
244Ejection Fraction DecreasedFAERS: 1US FAERS
245Emotional disorderFAERS: 1US FAERS
246Emotional distressFAERS: 1US FAERS
247Endometrial disorderFAERS: 1US FAERS
248Endometrial thickeningFAERS: 1US FAERS
249EnterocolitisFAERS: 1US FAERS
250Erythema NodosumFAERS: 1US FAERS
251Extrinsic iliac vein compressionFAERS: 1US FAERS
252Eye RednessFAERS: 1US FAERS
253Facial paralysisFAERS: 1US FAERS
254Factor V Leiden mutationFAERS: 1US FAERS
255Fallopian tube obstructionFAERS: 1US FAERS
256Feeling ColdFAERS: 1US FAERS
257Fibroadenoma of breastFAERS: 1US FAERS
258FlatulenceFAERS: 1US FAERS
259Focal Nodular HyperplasiaFAERS: 1US FAERS
260Food AllergyFAERS: 1US FAERS
261FormicationFAERS: 1OFFSIDES
US FAERS
262FractureFAERS: 1US FAERS
263Gastric infectionFAERS: 1US FAERS
264Gastric ulcerFAERS: 1US FAERS
265Gastrointestinal PainFAERS: 1US FAERS
266Gastrointestinal infectionFAERS: 1US FAERS
267General physical health deteriorationFAERS: 1US FAERS
268Gestational DiabetesFAERS: 1US FAERS
269GingivitisFAERS: 1US FAERS
270Hearing disabilityFAERS: 1US FAERS
271HepatitisFAERS: 1US FAERS
272HordeolumFAERS: 1US FAERS
273HyperchlorhydriaFAERS: 1US FAERS
274HypokinesiaFAERS: 1US FAERS
275HypoxiaFAERS: 1US FAERS
276IleusFAERS: 1US FAERS
277Impaired quality of lifeFAERS: 1US FAERS
278Incision site infectionFAERS: 1US FAERS
279IncoherentFAERS: 1US FAERS
280Increased upper airway secretionFAERS: 1US FAERS
281InfarctionFAERS: 1US FAERS
282InfluenzaFAERS: 1US FAERS
283Intentional product use issueFAERS: 1US FAERS
284Intentional self-injuryFAERS: 1OFFSIDES
US FAERS
285Intermittent ClaudicationFAERS: 1US FAERS
286Lactose IntoleranceFAERS: 1US FAERS
287Laryngeal neoplasmFAERS: 1US FAERS
288LethargyFAERS: 1OFFSIDES
US FAERS
289Low birth weight babyFAERS: 1US FAERS
290Lung cystFAERS: 1US FAERS
291LymphadenopathyFAERS: 1US FAERS
292Mass excisionFAERS: 1US FAERS
293May-Thurner SyndromeFAERS: 1US FAERS
294Medication tamperingFAERS: 1US FAERS
295MeningiomaFAERS: 1US FAERS
296MeningitisFAERS: 1US FAERS
297Meniscus injuryFAERS: 1US FAERS
298Mental impairmentFAERS: 1US FAERS
299Migraine with AuraFAERS: 1US FAERS
300Musculoskeletal stiffnessFAERS: 1US FAERS
301MydriasisFAERS: 1US FAERS
302MyofascitisFAERS: 1OFFSIDES
US FAERS
303MyomectomyFAERS: 1US FAERS
304MyopathyFAERS: 1US FAERS
305MyositisFAERS: 1US FAERS
306NasopharyngitisFAERS: 1OFFSIDES
US FAERS
307Neonatal aspirationFAERS: 1US FAERS
308NephrocalcinosisFAERS: 1US FAERS
309Nephrotic SyndromeFAERS: 1US FAERS
310NervousnessFAERS: 1US FAERS
311NeuralgiaFAERS: 1US FAERS
312Neuromyelitis OpticaFAERS: 1US FAERS
313No adverse eventFAERS: 1US FAERS
314NoduleFAERS: 1US FAERS
315ObesityFAERS: 1US FAERS
316Ocular discomfortFAERS: 1US FAERS
317Ocular vascular disorderFAERS: 1US FAERS
318Oculogyric crisisFAERS: 1US FAERS
319Panic DisorderFAERS: 1US FAERS
320ParanoiaFAERS: 1US FAERS
321Pelvic Inflammatory DiseaseFAERS: 1US FAERS
322Pelvic venous thrombosisFAERS: 1US FAERS
323Peripheral embolismFAERS: 1US FAERS
324Pityriasis Rubra PilarisFAERS: 1US FAERS
325PneumothoraxFAERS: 1US FAERS
326PolyneuropathyFAERS: 1US FAERS
327Poor peripheral circulationFAERS: 1US FAERS
328Poor quality drug administeredFAERS: 1US FAERS
329Portal Vein ThrombosisFAERS: 1OFFSIDES
US FAERS
330Post procedural complicationFAERS: 1US FAERS
331Pregnancy on contraceptiveFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
332Prescribed overdoseFAERS: 1US FAERS
333PresyncopeFAERS: 1US FAERS
334Procedural complicationFAERS: 1US FAERS
335Product label issueFAERS: 1US FAERS
336Product packaging confusionFAERS: 1US FAERS
337Productive CoughFAERS: 1US FAERS
338Protein C decreasedFAERS: 1US FAERS
339Protein S decreasedFAERS: 1US FAERS
340Prothrombin level decreasedFAERS: 1US FAERS
341Quality of life decreasedFAERS: 1US FAERS
342Renal cystFAERS: 1US FAERS
343Reverse tri-iodothyronine increasedFAERS: 1US FAERS
344RhabdomyolysisFAERS: 1US FAERS
345Ruptured ectopic pregnancyFAERS: 1US FAERS
346SchizophreniaFAERS: 1US FAERS
347ScleremaFAERS: 1US FAERS
348ScotomaFAERS: 1US FAERS
349Secretion dischargeFAERS: 1US FAERS
350Separation Anxiety DisorderFAERS: 1US FAERS
351SinusitisFAERS: 1US FAERS
352Skeletal injuryFAERS: 1US FAERS
353Splenic InfarctionFAERS: 1US FAERS
354Sudden deathFAERS: 1US FAERS
355Suicide attemptFAERS: 1US FAERS
356Suppressed lactationFAERS: 1US FAERS
357TalipesFAERS: 1US FAERS
358TensionFAERS: 1US FAERS
359Therapeutic response changedFAERS: 1US FAERS
360Therapy non-responderFAERS: 1US FAERS
361ThrombocytopeniaFAERS: 1US FAERS
362ThrombophlebitisFAERS: 1US FAERS
363Thrombotic strokeFAERS: 1US FAERS
364Tolosa-Hunt SyndromeFAERS: 1US FAERS
365TonsillectomyFAERS: 1US FAERS
366TonsillitisFAERS: 1US FAERS
367Tooth AvulsionFAERS: 1US FAERS
368Tooth repairFAERS: 1US FAERS
369Total lung capacity abnormalFAERS: 1US FAERS
370TrachomaFAERS: 1US FAERS
371Transaminases increasedFAERS: 1US FAERS
372TuberculosisFAERS: 1US FAERS
373Urinary RetentionFAERS: 1US FAERS
374Uterine CancerFAERS: 1US FAERS
375Uterine PolypFAERS: 1US FAERS
376VIIth nerve paralysisFAERS: 1US FAERS
377Varicose vein operationFAERS: 1US FAERS
378Vascular ruptureFAERS: 1US FAERS
379Venous InsufficiencyFAERS: 1US FAERS
380Ventricular FibrillationFAERS: 1US FAERS
381Visual acuity reduced transientlyFAERS: 1US FAERS
382Vulvovaginal burning sensationFAERS: 1US FAERS
383Vulvovaginal painFAERS: 1US FAERS
384furuncleFAERS: 1US FAERS
385nervous system disorderFAERS: 1US FAERS
386neurofibromaFAERS: 1US FAERS
387AgraphiaOFFSIDES
388ApathyOFFSIDES
389Application site erythemaOFFSIDES
390Application site painOFFSIDES
391Blood glucose fluctuationOFFSIDES
392Body TemperatureOFFSIDES
393Choking sensationOFFSIDES
394CholangiolitisOFFSIDES
395Chronic ulcerative colitisOFFSIDES
396Drug exposure before pregnancyOFFSIDES
397Drug exposure via breast milkOFFSIDES
398Drug specific antibody presentOFFSIDES
399Dysmenorrhea12499030CTD
400Fatty LiverOFFSIDES
401Feelings of worthlessnessOFFSIDES
402Hepatitis B positiveOFFSIDES
403Hypoaesthesia facialOFFSIDES
404Muscle WeaknessOFFSIDES
405OliguriaOFFSIDES
406Oropharyngeal swellingOFFSIDES
407Ovarian Hyperstimulation SyndromeOFFSIDES
408Polycystic Ovary Syndrome17105841CTD
409Protein C increasedOFFSIDES
410Pyloric StenosisOFFSIDES
411Rectal tenesmusOFFSIDES
412Respiratory FailureOFFSIDES
413Stool analysis abnormalOFFSIDES
414Thrombophilia11994571CTD
415Venous Thromboembolism7500750
10357966
16730485
CTD
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