MetaADEDB 2.0 @ LMMD
Propranolol
(AQHHHDLHHXJYJD-UHFFFAOYSA-N)
Structure
SMILES
OC(COc1cccc2c1cccc2)CNC(C)C
Type(s)
Approved; Investigational
ATC code(s)
C07AA05; C07BA05; C07FX01
Molecular Formula:
C16H21NO2
Molecular Weight:
259.343
Log P:
2.9684
Hydrogen Bond Acceptor:
3
Hydrogen Bond Donor:
2
TPSA:
41.49
CAS Number(s):
525-66-6; 13013-17-7
Synonym(s)
1.
Propranolol
2.
Dexpropranolol
3.
AY-20694
4.
Anaprilin
5.
Anapriline
6.
Avlocardyl
7.
Betadren
8.
Dociton
9.
Inderal
10.
Obsidan
11.
Obzidan
12.
Propanolol
13.
Propranolol Hydrochloride
14.
Rexigen
15.
AY 20694
16.
AY20694
17.
Hydrochloride, Propranolol
External Link(s)
MeSHD011433
PubChem Compound4946
BindingDB25761
ChEBI8499
CHEMBLCHEMBL27
DrugBankDB00571
DrugCentral2303
IUPHAR/BPS Guide to PHARMACOLOGY564
KEGGdr:D08443
cpd:C07407
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1BradycardiaFAERS: 95
Canada Vigilance: 10

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CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
2HypotensionFAERS: 82
Canada Vigilance: 8

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CTD
Canada Vigilance
US FAERS
3OverdoseFAERS: 73US FAERS
4Drug ineffectiveFAERS: 66
Canada Vigilance: 31
Canada Vigilance
US FAERS
5Cardiac ArrestFAERS: 61
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
6DizzinessFAERS: 53
Canada Vigilance: 7
4151696
5086971
CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
7PalpitationsFAERS: 43
Canada Vigilance: 1
Canada Vigilance
US FAERS
8Toxicity to various agentsFAERS: 43US FAERS
9FatigueFAERS: 42
Canada Vigilance: 6

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CTD
SIDER
Canada Vigilance
US FAERS
10HeadacheFAERS: 36
Canada Vigilance: 4
Canada Vigilance
US FAERS
11Completed SuicideFAERS: 34US FAERS
12Pharmaceutical product complaintFAERS: 30US FAERS
13VomitingFAERS: 30
Canada Vigilance: 4
Canada Vigilance
SIDER
US FAERS
14NauseaFAERS: 28
Canada Vigilance: 9
Canada Vigilance
OFFSIDES
SIDER
US FAERS
15Unresponsive to stimuliFAERS: 27OFFSIDES
US FAERS
16TachycardiaFAERS: 26
Canada Vigilance: 2

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CTD
Canada Vigilance
US FAERS
17Product substitution issueFAERS: 25US FAERS
18Product use in unapproved indicationFAERS: 22
Canada Vigilance: 1
Canada Vigilance
US FAERS
19Respiratory arrestFAERS: 22US FAERS
20Chest PainFAERS: 21
Canada Vigilance: 2
1644093CTD
OFFSIDES
Canada Vigilance
US FAERS
21CyanosisFAERS: 21
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
22Drug administered to patient of inappropriate ageFAERS: 20US FAERS
23SomnolenceFAERS: 20
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
24Product use issueFAERS: 19
Canada Vigilance: 1
Canada Vigilance
US FAERS
25ShockFAERS: 19US FAERS
26AnxietyFAERS: 18
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
27Feeling abnormalFAERS: 18
Canada Vigilance: 1
Canada Vigilance
US FAERS
28Sinus bradycardiaFAERS: 18US FAERS
29Suicide attemptFAERS: 18US FAERS
30SyncopeFAERS: 18
Canada Vigilance: 1
1879988
4539152
15028050
CTD
Canada Vigilance
US FAERS
31Chest discomfortFAERS: 17
Canada Vigilance: 4
Canada Vigilance
US FAERS
32Drug toxicityFAERS: 17US FAERS
33MalaiseFAERS: 17US FAERS
34TremorFAERS: 17
Canada Vigilance: 1

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CTD
Canada Vigilance
US FAERS
35Abdominal discomfortFAERS: 16
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
US FAERS
36AstheniaFAERS: 15
Canada Vigilance: 4
Canada Vigilance
OFFSIDES
SIDER
US FAERS
37Depressed Level of ConsciousnessFAERS: 15OFFSIDES
US FAERS
38Poor quality sleepFAERS: 15SIDER
US FAERS
39WheezingFAERS: 15US FAERS
40Bronchial HyperreactivityFAERS: 14US FAERS
41Memory impairmentFAERS: 14US FAERS
42Therapeutic response unexpected with drug substitutionFAERS: 14US FAERS
43PallorFAERS: 13
Canada Vigilance: 1
Canada Vigilance
US FAERS
44Product quality issueFAERS: 13US FAERS
45RestlessnessFAERS: 13US FAERS
46ArthralgiaFAERS: 11
Canada Vigilance: 1
Canada Vigilance
US FAERS
47Euphoric moodFAERS: 11US FAERS
48LethargyFAERS: 11
Canada Vigilance: 2
Canada Vigilance
OFFSIDES
SIDER
US FAERS
49Metabolic acidosisFAERS: 11OFFSIDES
US FAERS
50treatment failureFAERS: 11US FAERS
51AsthmaFAERS: 10
Canada Vigilance: 1
8687243CTD
Canada Vigilance
US FAERS
52BronchospasmFAERS: 10
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
53ConstipationFAERS: 10
Canada Vigilance: 1
5086971CTD
SIDER
Canada Vigilance
US FAERS
54Disease recurrenceFAERS: 10US FAERS
55Incorrect dose administeredFAERS: 10US FAERS
56Sinus TachycardiaFAERS: 10US FAERS
57Accidental overdoseFAERS: 9US FAERS
58Atrial FibrillationFAERS: 93709557
8908332
CTD
US FAERS
59Blood glucose decreasedFAERS: 9OFFSIDES
SIDER
US FAERS
60Drug withdrawal syndromeFAERS: 9US FAERS
61EpilepsyFAERS: 9US FAERS
62HypoxiaFAERS: 9OFFSIDES
US FAERS
63PoisoningFAERS: 97629900CTD
US FAERS
64Respiratory FailureFAERS: 9US FAERS
65Visual ImpairmentFAERS: 9
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
66AgitationFAERS: 8
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
67AmnesiaFAERS: 8
Canada Vigilance: 1
1423339
3097711
CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
68Atrioventricular BlockFAERS: 8

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CTD
SIDER
US FAERS
69Drug dispensing errorFAERS: 8US FAERS
70General physical health deteriorationFAERS: 8OFFSIDES
US FAERS
71MydriasisFAERS: 8US FAERS
72Myocardial InfarctionFAERS: 8
Canada Vigilance: 1

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CTD
Canada Vigilance
US FAERS
73PainFAERS: 86831328
16099101
16563475
CTD
SIDER
US FAERS
74DisorientationFAERS: 7
Canada Vigilance: 2
Canada Vigilance
SIDER
US FAERS
75Medication ErrorFAERS: 7US FAERS
76Supraventricular tachycardiaFAERS: 7US FAERS
77AlopeciaFAERS: 6
Canada Vigilance: 5
Canada Vigilance
SIDER
US FAERS
78Depressed moodFAERS: 6OFFSIDES
US FAERS
79KetoacidosisFAERS: 6US FAERS
80SepsisFAERS: 6US FAERS
81TinnitusFAERS: 65786777CTD
US FAERS
82Wrong drug administeredFAERS: 6US FAERS
83Abdominal PainFAERS: 5
Canada Vigilance: 3
Canada Vigilance
OFFSIDES
SIDER
US FAERS
84Accidental drug intake by childFAERS: 5US FAERS
85Adverse eventFAERS: 5US FAERS
86AnuriaFAERS: 5US FAERS
87Blood lactate dehydrogenase increasedFAERS: 5US FAERS
88BronchiolitisFAERS: 5SIDER
US FAERS
89ChillsFAERS: 5US FAERS
90Cold sweatFAERS: 5US FAERS
91DiplopiaFAERS: 56126700CTD
OFFSIDES
US FAERS
92DiscomfortFAERS: 5US FAERS
93Drug exposure during pregnancyFAERS: 5OFFSIDES
US FAERS
94Drug ineffective for unapproved indicationFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
95DysarthriaFAERS: 5
Canada Vigilance: 1
Canada Vigilance
US FAERS
96Facial ParesisFAERS: 5US FAERS
97HypersensitivityFAERS: 5SIDER
US FAERS
98Mental status changesFAERS: 5OFFSIDES
US FAERS
99MyalgiaFAERS: 5US FAERS
100NasopharyngitisFAERS: 5US FAERS
101NervousnessFAERS: 5US FAERS
102Respiratory distressFAERS: 5SIDER
US FAERS
103Sclerosing encapsulating peritonitisFAERS: 5US FAERS
104ThrombocytopeniaFAERS: 511871761CTD
US FAERS
105UrticariaFAERS: 5
Canada Vigilance: 3
Canada Vigilance
SIDER
US FAERS
106Ventricular hypertrophyFAERS: 5US FAERS
107nervous system disorderFAERS: 5SIDER
US FAERS
108Acute kidney injuryFAERS: 419945959CTD
US FAERS
109AphasiaFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
110AtelectasisFAERS: 4US FAERS
111Cardiac FlutterFAERS: 4US FAERS
112CholelithiasisFAERS: 4US FAERS
113Drug titration errorFAERS: 4US FAERS
114Feeling ColdFAERS: 4SIDER
US FAERS
115HypoperfusionFAERS: 4US FAERS
116Inappropriate schedule of drug administrationFAERS: 4US FAERS
117InflammationFAERS: 4US FAERS
118Intentional misuseFAERS: 4US FAERS
119Labile blood pressureFAERS: 4US FAERS
120Livedo ReticularisFAERS: 4US FAERS
121Oropharyngeal painFAERS: 4OFFSIDES
SIDER
US FAERS
122Peripheral swellingFAERS: 4
Canada Vigilance: 1
Canada Vigilance
US FAERS
123PresyncopeFAERS: 4US FAERS
124Product administered to patient of inappropriate ageFAERS: 4US FAERS
125PruritusFAERS: 4
Canada Vigilance: 5
Canada Vigilance
US FAERS
126PsoriasisFAERS: 4US FAERS
127ScreamingFAERS: 4US FAERS
128Septic ShockFAERS: 4US FAERS
129Skin UlcerFAERS: 4SIDER
US FAERS
130UlcerFAERS: 4US FAERS
131Weight decreasedFAERS: 4US FAERS
132Activities of daily living impairedFAERS: 3US FAERS
133Alanine Aminotransferase IncreasedFAERS: 3US FAERS
134Angina PectorisFAERS: 3
Canada Vigilance: 2

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CTD
Canada Vigilance
US FAERS
135Colonic Pseudo-ObstructionFAERS: 3US FAERS
136Deep Vein ThrombosisFAERS: 3US FAERS
137Drug administration errorFAERS: 3US FAERS
138DysgeusiaFAERS: 3US FAERS
139Ear discomfortFAERS: 3OFFSIDES
US FAERS
140Erectile dysfunctionFAERS: 3

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CTD
SIDER
US FAERS
141ErythemaFAERS: 3
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
SIDER
US FAERS
142Exposure via ingestionFAERS: 3US FAERS
143Feeding disorder of infancy OR early childhoodFAERS: 3US FAERS
144Feeling of body temperature changeFAERS: 3US FAERS
145FlatulenceFAERS: 3
Canada Vigilance: 1
Canada Vigilance
US FAERS
146GoutFAERS: 3US FAERS
147HungerFAERS: 3US FAERS
148HypophagiaFAERS: 3US FAERS
149Increased tendency to bruiseFAERS: 3US FAERS
150Intentional product misuseFAERS: 3US FAERS
151Intentional product use issueFAERS: 3US FAERS
152Joint swellingFAERS: 3US FAERS
153Left Ventricular HypertrophyFAERS: 3US FAERS
154Libido disorderFAERS: 3US FAERS
155Limb discomfortFAERS: 3US FAERS
156Lip swellingFAERS: 3US FAERS
157Lower respiratory tract infectionFAERS: 3SIDER
US FAERS
158Mood swingsFAERS: 3SIDER
US FAERS
159Non-cardiac chest painFAERS: 3US FAERS
160Product physical issueFAERS: 3US FAERS
161Product solubility abnormalFAERS: 3US FAERS
162Product use complaintFAERS: 3US FAERS
163Sudden deathFAERS: 3OFFSIDES
US FAERS
164SwellingFAERS: 3US FAERS
165Temperature intoleranceFAERS: 3US FAERS
166Therapeutic response unexpectedFAERS: 3OFFSIDES
US FAERS
167Throat irritationFAERS: 3US FAERS
168ThrombosisFAERS: 3US FAERS
169Tonic clonic movementsFAERS: 3US FAERS
170Tumour haemorrhageFAERS: 3US FAERS
171Urinary RetentionFAERS: 3US FAERS
172Viral upper respiratory tract infectionFAERS: 3US FAERS
173Accelerated Idioventricular RhythmFAERS: 2US FAERS
174Accidental exposure to product by childFAERS: 2US FAERS
175Altered state of consciousnessFAERS: 2US FAERS
176AngerFAERS: 2US FAERS
177AngioedemaFAERS: 220592324CTD
US FAERS
178ApathyFAERS: 2US FAERS
179AscitesFAERS: 26476994CTD
OFFSIDES
US FAERS
180BedriddenFAERS: 2US FAERS
181Blood creatine phosphokinase increasedFAERS: 2OFFSIDES
US FAERS
182Blood glucose abnormalFAERS: 2US FAERS
183Blood pressure fluctuationFAERS: 2US FAERS
184Breath HoldingFAERS: 2US FAERS
185Burning sensationFAERS: 2OFFSIDES
US FAERS
186CataractFAERS: 2US FAERS
187Cerebral disorderFAERS: 2US FAERS
188Chronotropic incompetenceFAERS: 2US FAERS
189DehydrationFAERS: 2US FAERS
190Disease ProgressionFAERS: 2US FAERS
191Disseminated Intravascular CoagulationFAERS: 2US FAERS
192Drug resistanceFAERS: 2US FAERS
193DysgraphiaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
194DyspepsiaFAERS: 2
Canada Vigilance: 3
5086971CTD
SIDER
Canada Vigilance
US FAERS
195Economic problemFAERS: 2US FAERS
196Ejection Fraction DecreasedFAERS: 2US FAERS
197Emotional distressFAERS: 2OFFSIDES
US FAERS
198Exposure during breast feedingFAERS: 2US FAERS
199Failure to ThriveFAERS: 2OFFSIDES
US FAERS
200Gamma-Glutamyltransferase IncreasedFAERS: 2US FAERS
201HepatitisFAERS: 2US FAERS
202HypersomniaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
203HypoventilationFAERS: 2US FAERS
204Impaired work abilityFAERS: 2US FAERS
205Increased bronchial secretionFAERS: 2US FAERS
206InfluenzaFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
207Initial insomniaFAERS: 2US FAERS
208Intestinal ObstructionFAERS: 2US FAERS
209Metanephrine urine increasedFAERS: 2US FAERS
210Multiple drug overdoseFAERS: 2US FAERS
211NecrosisFAERS: 2698989
1258789
10533957
CTD
US FAERS
212Neonatal disorderFAERS: 2US FAERS
213OsteoporosisFAERS: 224250662CTD
US FAERS
214ParesisFAERS: 2US FAERS
215Pharyngolaryngeal PainFAERS: 2US FAERS
216Pityriasis RoseaFAERS: 2US FAERS
217Procedural complicationFAERS: 2US FAERS
218Product formulation issueFAERS: 2US FAERS
219Reaction to drug excipientsFAERS: 2US FAERS
220Rebound effectFAERS: 2US FAERS
221RosaceaFAERS: 2US FAERS
222Secretion dischargeFAERS: 2US FAERS
223SluggishnessFAERS: 2US FAERS
224SomnambulismFAERS: 2
Canada Vigilance: 1
Canada Vigilance
US FAERS
225StaringFAERS: 2US FAERS
226Status EpilepticusFAERS: 2US FAERS
227StuporFAERS: 2US FAERS
228Sudden infant death syndromeFAERS: 2US FAERS
229Therapeutic response changedFAERS: 2US FAERS
230Therapy cessationFAERS: 2US FAERS
231TrismusFAERS: 2US FAERS
232Urinary tract infectionFAERS: 2US FAERS
233VertigoFAERS: 2
Canada Vigilance: 1
Canada Vigilance
SIDER
US FAERS
234Wolff-Parkinson-White SyndromeFAERS: 24067758CTD
US FAERS
235AbasiaFAERS: 1US FAERS
236AcidosisFAERS: 1US FAERS
237Adrenal massFAERS: 1US FAERS
238AdrenalectomyFAERS: 1US FAERS
239AgranulocytosisFAERS: 1SIDER
US FAERS
240Alcohol test false positiveFAERS: 1US FAERS
241Allergic reaction to excipientFAERS: 1US FAERS
242Amino acid level increasedFAERS: 1US FAERS
243Anaphylactic shockFAERS: 1SIDER
US FAERS
244Aspartate Aminotransferase IncreasedFAERS: 1US FAERS
245Atrial FlutterFAERS: 17294224CTD
OFFSIDES
US FAERS
246AuraFAERS: 1US FAERS
247Back PainFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
248Blood alkaline phosphatase increasedFAERS: 1OFFSIDES
US FAERS
249Blood cholesterol increasedFAERS: 1US FAERS
250Blood creatine phosphokinase MB increasedFAERS: 1OFFSIDES
US FAERS
251Blood creatinine increasedFAERS: 1OFFSIDES
US FAERS
252Blood glucose increasedFAERS: 1US FAERS
253Blood ketone body increasedFAERS: 1US FAERS
254Blood potassium decreasedFAERS: 1US FAERS
255Blood potassium increasedFAERS: 1OFFSIDES
US FAERS
256Blood pressure inadequately controlledFAERS: 1US FAERS
257Blood sodium decreasedFAERS: 1US FAERS
258Bowel movement irregularityFAERS: 1US FAERS
259Brain DeathFAERS: 1US FAERS
260Brain stem syndromeFAERS: 1US FAERS
261Bronchial ObstructionFAERS: 1US FAERS
262BronchitisFAERS: 1SIDER
US FAERS
263Capillary nail refill test abnormalFAERS: 1US FAERS
264CardiomegalyFAERS: 1

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CTD
US FAERS
265Cardiovascular insufficiencyFAERS: 1US FAERS
266Cerebral congestionFAERS: 1US FAERS
267Cerebral ventricle dilatationFAERS: 1US FAERS
268Cerebrovascular accidentFAERS: 1US FAERS
269Childhood disintegrative disorderFAERS: 1US FAERS
270ChokingFAERS: 1US FAERS
271CholecystitisFAERS: 1US FAERS
272Cluster HeadacheFAERS: 1US FAERS
273Concomitant disease aggravatedFAERS: 1US FAERS
274Consciousness fluctuatingFAERS: 1US FAERS
275Contraindicated product administeredFAERS: 1US FAERS
276CryingFAERS: 1US FAERS
277Decreased eye contactFAERS: 1US FAERS
278DeformityFAERS: 1US FAERS
279DeliriumFAERS: 1

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CTD
US FAERS
280Delusional disorder, persecutory typeFAERS: 1US FAERS
281DementiaFAERS: 1US FAERS
282Dental cariesFAERS: 1US FAERS
283Device allergyFAERS: 1US FAERS
284Device ineffectiveFAERS: 1US FAERS
285Device malfunctionFAERS: 1US FAERS
286Drug dose omissionFAERS: 1US FAERS
287Drug effect incompleteFAERS: 1US FAERS
288Drug level decreasedFAERS: 1US FAERS
289Drug prescribing errorFAERS: 1US FAERS
290Drug screen false positiveFAERS: 1US FAERS
291DysphoniaFAERS: 1US FAERS
292DysuriaFAERS: 1OFFSIDES
US FAERS
293Echocardiogram abnormalFAERS: 1US FAERS
294EczemaFAERS: 1OFFSIDES
US FAERS
295Electrocardiogram changeFAERS: 1US FAERS
296Electromechanical dissociationFAERS: 1US FAERS
297Emotional disorderFAERS: 1US FAERS
298Enterobacter test positiveFAERS: 1US FAERS
299Escherichia sepsisFAERS: 1US FAERS
300Excessive ocular convergenceFAERS: 1US FAERS
301Exposure via breast milkFAERS: 1US FAERS
302Eye painFAERS: 1US FAERS
303Feeling jitteryFAERS: 1US FAERS
304FlushingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
305Food aversionFAERS: 1US FAERS
306FormicationFAERS: 1OFFSIDES
US FAERS
307GastroenteritisFAERS: 1US FAERS
308Gastrointestinal infectionFAERS: 1US FAERS
309Hallucinations, mixedFAERS: 1OFFSIDES
US FAERS
310Head discomfortFAERS: 1US FAERS
311Hepatic EncephalopathyFAERS: 16411235CTD
US FAERS
312HostilityFAERS: 1US FAERS
313HyperphagiaFAERS: 1US FAERS
314HyperpyrexiaFAERS: 1US FAERS
315HyperthyroidismFAERS: 1

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CTD
US FAERS
316HypertrichosisFAERS: 1US FAERS
317HyperventilationFAERS: 1US FAERS
318HypothyroidismFAERS: 1US FAERS
319Impaired driving abilityFAERS: 1US FAERS
320Incorrect drug administration durationFAERS: 1US FAERS
321InfectionFAERS: 1SIDER
US FAERS
322Inflammatory marker increasedFAERS: 1US FAERS
323Intentional drug misuseFAERS: 1US FAERS
324Intentional self-injuryFAERS: 1US FAERS
325Intercepted drug dispensing errorFAERS: 1US FAERS
326Intercepted medication errorFAERS: 1US FAERS
327Intercepted product dispensing errorFAERS: 1US FAERS
328Intercepted product selection errorFAERS: 1US FAERS
329Intra-abdominal pressure increasedFAERS: 1US FAERS
330KetonuriaFAERS: 1US FAERS
331KetosisFAERS: 1US FAERS
332Lactose IntoleranceFAERS: 1US FAERS
333Laryngeal ObstructionFAERS: 1US FAERS
334Liver carcinoma rupturedFAERS: 1US FAERS
335Loss of personal independence in daily activitiesFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
336Low Cardiac Output SyndromeFAERS: 1US FAERS
337Lupus-like syndromeFAERS: 1US FAERS
338LymphohistiocytosisFAERS: 1US FAERS
339Maternal exposure during pregnancyFAERS: 1US FAERS
340Mucosal pigmentationFAERS: 1US FAERS
341Muscle SpasticityFAERS: 1US FAERS
342Myocardial necrosis marker increasedFAERS: 1US FAERS
343NarcolepsyFAERS: 1US FAERS
344Nasal discomfortFAERS: 1US FAERS
345Neck PainFAERS: 1US FAERS
346Neonatal hypotensionFAERS: 1US FAERS
347NephritisFAERS: 1US FAERS
348NephrolithiasisFAERS: 1US FAERS
349NeuroglycopeniaFAERS: 1US FAERS
350NeutropeniaFAERS: 1SIDER
US FAERS
351Neutrophil count decreasedFAERS: 1US FAERS
352No adverse eventFAERS: 1US FAERS
353ObesityFAERS: 1US FAERS
354Obsessive-Compulsive DisorderFAERS: 1US FAERS
355PO2 decreasedFAERS: 1US FAERS
356Panic DisorderFAERS: 13379142
6871816
CTD
US FAERS
357Paradoxical drug reactionFAERS: 1US FAERS
358ParanoiaFAERS: 1
Canada Vigilance: 1
Canada Vigilance
OFFSIDES
US FAERS
359ParasomniaFAERS: 1US FAERS
360Peritoneal FibrosisFAERS: 1US FAERS
361PetechiaeFAERS: 1US FAERS
362Pneumatosis intestinalisFAERS: 1US FAERS
363PneumoniaFAERS: 1US FAERS
364Poor peripheral circulationFAERS: 1US FAERS
365Portal hypertensive gastropathyFAERS: 1US FAERS
366Post procedural complicationFAERS: 1US FAERS
367Pre-existing condition improvedFAERS: 1US FAERS
368PregnancyFAERS: 1US FAERS
369Product administration errorFAERS: 1US FAERS
370Product dispensing errorFAERS: 1US FAERS
371Product label confusionFAERS: 1US FAERS
372Product outer packaging issueFAERS: 1US FAERS
373Pseudomonal sepsisFAERS: 1US FAERS
374Pulmonary Valve StenosisFAERS: 1OFFSIDES
US FAERS
375Pulmonary congestionFAERS: 1US FAERS
376Pulmonary radiation injuryFAERS: 1US FAERS
377Radial pulse decreasedFAERS: 1US FAERS
378Respiratory syncytial virus test positiveFAERS: 1US FAERS
379Respiratory tract infection viralFAERS: 1US FAERS
380Restless Legs SyndromeFAERS: 13717447CTD
US FAERS
381RetchingFAERS: 1US FAERS
382Retinal vascular thrombosisFAERS: 1US FAERS
383Rheumatoid ArthritisFAERS: 1US FAERS
384Serotonin SyndromeFAERS: 115707818CTD
US FAERS
385Sick Sinus SyndromeFAERS: 1657866CTD
US FAERS
386Sinus rhythmFAERS: 1US FAERS
387Skin graft rejectionFAERS: 1US FAERS
388Skin lacerationFAERS: 1US FAERS
389Skin lesionFAERS: 1US FAERS
390Skin necrosisFAERS: 1US FAERS
391Sleep ParalysisFAERS: 1US FAERS
392Sleep TalkingFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
393Stevens-Johnson SyndromeFAERS: 125811541CTD
SIDER
US FAERS
394StillbirthFAERS: 1US FAERS
395Stress ulcerFAERS: 1US FAERS
396StressFAERS: 1US FAERS
397Systemic Inflammatory Response SyndromeFAERS: 1US FAERS
398TensionFAERS: 1US FAERS
399Therapy changeFAERS: 1US FAERS
400Therapy non-responderFAERS: 1OFFSIDES
US FAERS
401Therapy regimen changedFAERS: 1US FAERS
402Therapy responderFAERS: 1US FAERS
403Tongue discomfortFAERS: 1US FAERS
404Tongue pigmentationFAERS: 1US FAERS
405TrichorrhexisFAERS: 1US FAERS
406Tryptase increasedFAERS: 1US FAERS
407Unevaluable eventFAERS: 1US FAERS
408Unresponsive to verbal stimuliFAERS: 1US FAERS
409Upper-airway cough syndromeFAERS: 1US FAERS
410Urinary IncontinenceFAERS: 1US FAERS
411Uterine PolypFAERS: 1US FAERS
412Vascular ruptureFAERS: 1OFFSIDES
US FAERS
413Ventricular DysfunctionFAERS: 1US FAERS
414Ventricular FibrillationFAERS: 1

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CTD
OFFSIDES
US FAERS
415Ventricular arrhythmiaFAERS: 1US FAERS
416Vulvovaginal drynessFAERS: 1US FAERS
417Wrong scheduleFAERS: 1
Canada Vigilance: 1
Canada Vigilance
US FAERS
418Wrong technique in drug usage processFAERS: 1US FAERS
419Wrong technique in product usage processFAERS: 1US FAERS
420Abdominal CrampsSIDER
421AbscessOFFSIDES
422AbuseOFFSIDES
423Accidental deathOFFSIDES
424Accidental exposureOFFSIDES
425AcheSIDER
426AcneCanada Vigilance: 1Canada Vigilance
427Acute psychosisOFFSIDES
428Adams-Stokes Syndrome5450475
5606811
CTD
429Akathisia, Drug-Induced

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CTD
430Alcohol Withdrawal Delirium6122874CTD
431Alcohol abuseOFFSIDES
432Alkalosis635611CTD
433Ammonia increasedOFFSIDES
434Anaphylactoid ReactionSIDER
435Aneurysm8958985CTD
436AngiodysplasiaOFFSIDES
437Angiogram cerebral abnormalOFFSIDES
438Anomia7471772
17886000
CTD
439Anorexia2140288CTD
OFFSIDES
440Anxiety Disorders

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CTD
441Aortic RuptureOFFSIDES
442Apnea2065423CTD
OFFSIDES
443AppendicitisOFFSIDES
444Application site irritationOFFSIDES
445Application site massOFFSIDES
446Arterial insufficiencySIDER
447Arterial thrombosisSIDER
448ArthropathyOFFSIDES
449AsterixisOFFSIDES
450AsthenopiaOFFSIDES
451Ataxia4441828CTD
452Atherosclerosis1893141CTD
453Attention Deficit and Disruptive Behavior Disorders15764868CTD
454Autistic Disorder18766980CTD
455Bacterial sepsisOFFSIDES
456Basal Ganglia Diseases6122382
12900300
CTD
457Basal cell carcinomaOFFSIDES
458Bipolar Disorder6505774CTD
459Bladder discomfortOFFSIDES
460Bladder spasmOFFSIDES
461Blood GlucoseOFFSIDES
462Blood Platelet Disorders10808734CTD
463Blood and lymphatic system disordersSIDER
464Blood cortisol decreasedOFFSIDES
465Blood creatine increasedOFFSIDES
466Blood pH decreasedOFFSIDES
467Blood pressure immeasurableOFFSIDES
468Blood triglycerides increasedOFFSIDES
469Body TemperatureOFFSIDES
470Bone painOFFSIDES
471Candida serology positiveOFFSIDES
472Cardiac Output, High1696669
3987172
6434220
CTD
473Cardiomyopathies10533957
10908085
21191138
CTD
474Carpal Tunnel Syndrome3140228CTD
475Catalepsy2879054
9201797
CTD
476CatatoniaSIDER
477CellulitisOFFSIDES
478Cerebellar Ataxia11096749CTD
479Cerebral atrophyOFFSIDES
480Cervicobrachial syndromeOFFSIDES
481Chemical and Drug Induced Liver Injury3984541
24085192
CTD
482Chemical burn of skinOFFSIDES
483Choking sensationOFFSIDES
484Cholestasis of pregnancyOFFSIDES
485ChromaturiaOFFSIDES
486Chronic Obstructive Airway DiseaseOFFSIDES
487CirrhosisOFFSIDES
488Clostridium difficile colitisOFFSIDES
489Cocaine-Related Disorders

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CTD
490Cognition Disorders2274600
8914496
18781429
CTD
491ColitisOFFSIDES
492ConfabulationOFFSIDES
493Confusion74595
723112
4441828
CTD
494Congenital HypothyroidismOFFSIDES
495ConjunctivitisCanada Vigilance: 1Canada Vigilance
496Coronary Artery Disease7498204
10808734
CTD
497Coronary Stenosis3110237CTD
498Coronary artery insufficiencyOFFSIDES
499Deafness65671CTD
500DemyelinationOFFSIDES
501Depressive disorder

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CTD
502DermatitisSIDER
503Device related infectionOFFSIDES
504DiabetesOFFSIDES
505Diastolic dysfunctionOFFSIDES
506Dieulafoy's vascular malformationOFFSIDES
507Disorders of Excessive Somnolence3665616
5086971
CTD
508DiverticulitisOFFSIDES
509Drug Eruptions17659030CTD
510Drug Overdose7001962CTD
511Drug abuserOFFSIDES
512Drug withdrawal headacheOFFSIDES
513Dyskinesia, Drug-Induced

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CTD
514Dyspnea6115999CTD
515Dysthymic DisorderOFFSIDES
516Dystonia589060
10768633
CTD
517EcchymosisCanada Vigilance: 1Canada Vigilance
518Embolic strokeOFFSIDES
519EmbolismOFFSIDES
520EndocarditisOFFSIDES
521EnuresisOFFSIDES
522Epigastric distressSIDER
523Erythema MultiformeSIDER
524Escherichia infectionOFFSIDES
525Esophageal and Gastric Varices

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CTD
526Essential Tremor

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CTD
OFFSIDES
527Exanthema1268509
5086971
CTD
528Facial NeuralgiaOFFSIDES
529Factitious Disorders436541CTD
530FibromyalgiaOFFSIDES
531Fluid overloadOFFSIDES
532FolliculitisCanada Vigilance: 1Canada Vigilance
533GamblingOFFSIDES
534Gastrointestinal Diseases4151696CTD
535Gastrointestinal Hemorrhage

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CTD
536Gastrointestinal PainSIDER
537GlaucomaOFFSIDES
538Global AmnesiaOFFSIDES
539Graves Disease7714072
9392993
17462097
CTD
540Growth Disorders573555CTD
541Hallucinations

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CTD
542Heart Block4151696
7905586
26831068
CTD
543Heart Diseases590302
8607134
CTD
544Heart failure

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CTD
545Helicobacter pylori identification test positiveOFFSIDES
546Hemangioma19743301
21493392
30130526
CTD
547Hemorrhage12475399
17622865
CTD
548Heparin-induced thrombocytopeniaOFFSIDES
549Hepatomegaly16371745CTD
550Hepatorenal Syndrome11051385CTD
551High density lipoprotein increasedOFFSIDES
552Hip surgeryOFFSIDES
553Hypercalcemia3013062CTD
554Hyperemia7949234CTD
555Hyperglycemia1032269
2575521
22305719
CTD
556Hyperkalemia16286062CTD
557Hypertensive emergencyOFFSIDES
558Hypertrophy11880281CTD
559Hypoglycemia909024
3019152
4710445
CTD
560Hypokalemia2600984
2885202
CTD
561Hypokinesia7927523CTD
562Hyponatremia635611CTD
563Hypotension, Orthostatic3799644
6110503
6872168
CTD
564Impaired gastric emptyingOFFSIDES
565Infectious MononucleosisOFFSIDES
566InfestationSIDER
567Injection site massOFFSIDES
568Intention tremorOFFSIDES
569Intermittent Claudication5171CTD
OFFSIDES
570IritisCanada Vigilance: 1Canada Vigilance
571Ischemia15701768CTD
572Joint injuryOFFSIDES
573Large intestine perforationOFFSIDES
574LaryngospasmSIDER
575LassitudeSIDER
576LightheadednessSIDER
577Live BirthOFFSIDES
578Liver Cirrhosis4007042
6327487
11871761
CTD
579Liver diseases11193444CTD
580Liver neoplasms19743301CTD
581Liver transplant rejectionOFFSIDES
582Long QT Syndrome

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CTD
583Memory Disorders

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CTD
584Mental disorders1003361
2957363
9324403
CTD
585Migraine Disorders

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CTD
586Migraine with Aura10759905CTD
587Mood Disorders4151696CTD
588Movement Disorders4051467
7146044
17306893
CTD
589Multiple MyelomaOFFSIDES
590Multiple sclerosis relapseOFFSIDES
591Muscle Rigidity6122382CTD
592Muscle Weakness519436
876285
CTD
OFFSIDES
593Myocardial Ischemia

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CTD
594Myocardial Reperfusion Injury10512524CTD
595Myoclonus2347607
7205315
CTD
596MyopathySIDER
597Myotonia876285CTD
SIDER
598Myotonic Dystrophy63714CTD
599Neoplasm Invasiveness24929186CTD
600Nephritis, Interstitial6948214CTD
601Nephrotic Syndrome1268509CTD
602NeuralgiaOFFSIDES
603Neurobehavioral Manifestations499336CTD
604Neuroleptic Malignant Syndrome10628507CTD
605Neurotoxicity Syndromes7471772CTD
606Neutropenic sepsisOFFSIDES
607NystagmusOFFSIDES
608Ocular Motility Disorders6831328CTD
609Oral polypectomyOFFSIDES
610Oral pruritusOFFSIDES
611Oropharyngeal discomfortSIDER
612PancreatitisOFFSIDES
613Pancytopenia11193444CTD
614Paresthesia699788CTD
615Parkinson Disease12588639CTD
616Peptic UlcerCanada Vigilance: 1Canada Vigilance
617PeriarthritisOFFSIDES
618Pericardial effusionOFFSIDES
619Peripheral arterial occlusive diseaseSIDER
620Peripheral artery occlusionCanada Vigilance: 1Canada Vigilance
621PharyngitisSIDER
622PhotophobiaCanada Vigilance: 1Canada Vigilance
623Pneumocystis jiroveci pneumoniaOFFSIDES
624Polyarteritis Nodosa1971779CTD
625PolyneuropathyOFFSIDES
626Polyploidy3546119CTD
627Post procedural infectionOFFSIDES
628Post-Exercise Hypotension8276050CTD
629Postoperative Complications316976CTD
630Postural Orthostatic Tachycardia Syndrome20860911CTD
631Pregnancy Complications, Cardiovascular6587733CTD
632Proteinuria1268509CTD
633Psychomotor Agitation

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CTD
634Psychophysiologic Disorders16415721CTD
635Psychoses, Substance-Induced

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CTD
636Psychotic Disorders2914157CTD
637Pulmonary Edema678897CTD
638Pulmonary HypertensionOFFSIDES
639Pulmonary artery stenosisOFFSIDES
640PurpuraCanada Vigilance: 1Canada Vigilance
SIDER
641Rash erythematousCanada Vigilance: 1Canada Vigilance
SIDER
642Raynaud Disease6109
520027
6115999
CTD
643Reaction to preservativesOFFSIDES
644Reflex, Abnormal7146044CTD
645Renal cystOFFSIDES
646Renal tubular disorderOFFSIDES
647Reperfusion Injury698989CTD
648Respiratory Insufficiency909024CTD
649Right Ventricular HypertrophyOFFSIDES
650Sarcoma, Experimental6123488CTD
651Schizophrenia Spectrum and Other Psychotic Disorders404537CTD
652Schizophrenia4441828CTD
653Seizures

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CTD
654Selective eating disorderCanada Vigilance: 1Canada Vigilance
655Shock, Cardiogenic1185021
7154501
10460701
CTD
656Signs and Symptoms, Digestive3524092CTD
657Sinoatrial Block6529939CTD
658Sleep Initiation and Maintenance Disorders4269335
5086971
11794720
CTD
659Sleep Wake Disorders2274600
4151696
6121825
CTD
660Sperm count decreasedOFFSIDES
661Spermatozoa progressive motility decreasedOFFSIDES
662SpondylitisOFFSIDES
663StomatitisCanada Vigilance: 1Canada Vigilance
664StridorCanada Vigilance: 1Canada Vigilance
665Substance Withdrawal Syndrome

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CTD
666T-Cell LymphomaOFFSIDES
667Tachycardia, Paroxysmal1115373CTD
668Tachycardia, Ventricular

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CTD
669Tardive DyskinesiaOFFSIDES
670ThirstCanada Vigilance: 1Canada Vigilance
671Thrombocytopenic purpuraSIDER
672Thyrotoxicosis4392540
8542214
CTD
673Torsades de Pointes7557819
8093399
20079908
CTD
674Toxic Epidermal NecrolysisSIDER
675Umbilical herniaOFFSIDES
676Urine output increasedOFFSIDES
677Vascular Diseases5819188CTD
678Vascular Headaches4472181CTD
679Vascular purpuraSIDER
680Vasculitis, Leukocytoclastic, Cutaneous2523289
10907976
17659030
CTD
681VasculitisCanada Vigilance: 1Canada Vigilance
682Ventricular Dysfunction, Left

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CTD
683Ventricular Outflow Obstruction9527943CTD
684Ventricular Remodeling20668454CTD
685Visual disturbanceOFFSIDES
SIDER
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