MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Refeeding Syndrome

(UMLS:C0860549)

Definition:: A condition of metabolic imbalance that is caused by complications of initially feeding a severely malnourished patient too aggressively. Usually occurring within the first 5 days of refeeding, this syndrome is characterized by WATER-ELECTROLYTE IMBALANCE; GLUCOSE INTOLERANCE; CARDIAC ARRHYTHMIAS; and DIARRHEA.
UMLS ID:: C0860549
MeSH ID:: D055677

Classification:

Name:

Nutritional and Metabolic Diseases
MeSH Tree Number(s):: C18.654.521.687

Synonym(s)

Refeeding Syndrome

Refeeding syndrome

refeed syndrome

refeeding syndrome

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Clozapine	FAERS: 1	US FAERS
2	Everolimus	FAERS: 1	US FAERS
3	carbidopa, levodopa drug combination	FAERS: 1	US FAERS
4	ceritinib	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Deficiency Diseases	46.7%
2	Starvation	46.7%
3	Kwashiorkor	34.4%
4	Magnesium Deficiency	34.4%
5	Potassium Deficiency	34.4%
6	Protein Deficiency	34.4%
7	Avitaminosis	34.4%
8	Child Nutrition Disorders	31%
9	Hypervitaminosis A	31%
10	Infant Nutrition Disorders	31%
11	Ascorbic Acid Deficiency	28.5%
12	Vitamin A Deficiency	28.5%
13	Vitamin D Deficiency	28.5%
14	Vitamin E Deficiency	28.5%
15	Marasmus	28.5%
16	Wasting Syndrome	27.9%
17	Folic Acid Deficiency	25.5%
18	Pellagra	25.5%
19	Thiamine Deficiency	25.5%
20	Vitamin B 12 Deficiency	25.5%
21	Vitamin B 6 Deficiency	25.5%
22	Pyridoxine Deficiency	25.5%
23	Beriberi	24%
24	Metabolic Diseases	18.5%
25	Anemia, Pernicious	15.9%
26	Rickets	15.7%
27	Hyperhomocysteinemia	14.8%
28	Vitamin K Deficiency	14.4%
29	Osteomalacia	13.5%
30	Scurvy	12.8%
31	Acid-Base Imbalance	10.3%
32	Calcium Metabolism Disorders	10.3%
33	Iron Metabolism Disorders	10.3%
34	Phosphorus Metabolism Disorders	10.3%
35	Water-Electrolyte Imbalance	10.3%
36	Lipid Metabolism Disorders	10.3%
37	Mitochondrial Diseases	10.3%
38	Glucose Metabolism Disorders	10.3%
39	Wernicke Encephalopathy	10.3%
40	Hypercalcemia	8.9%
41	Hypocalcemia	8.9%
42	Milk-Alkali Syndrome	8.9%
43	HIV Wasting Syndrome	8.8%
44	Renal Osteodystrophy	8.5%
45	Renal rickets	8.5%
46	Subacute Combined Degeneration	8.4%
47	Obesity	7.8%
48	Obesity, Abdominal	7.2%
49	Familial Hypophosphatemic Rickets	7.2%
50	Osteopenia	7%
51	Brain Diseases, Metabolic	6.8%
52	Acidosis	6.7%
53	Alkalosis	6.7%
54	Amyloidosis	6.7%
55	Calcinosis	6.7%
56	Hyperglycemia	6.7%
57	Hyperinsulinism	6.7%
58	Hyperkalemia	6.7%
59	Hypernatremia	6.7%
60	Hypoglycemia	6.7%
61	Hypokalemia	6.7%
62	Hyponatremia	6.7%
63	Lipodystrophy	6.7%
64	Xanthomatosis	6.7%
65	Hypophosphatemia	6.7%
66	Metabolic acidosis	6.7%
67	Dyslipidemias	6.7%
68	Iron Overload	6.7%
69	Xanthoma	6.7%
70	Pseudohypoparathyroidism	6%
71	Pediatric Obesity	5.8%
72	Brain Diseases, Metabolic, Inborn	5.3%
73	Leigh Disease	5.1%
74	Prader-Willi Syndrome	4.9%
75	Acidosis, Lactic	4.9%
76	Calciphylaxis	4.9%
77	Hemosiderosis	4.9%
78	Ketosis	4.9%
79	Ketonuria	4.9%
80	Ketoacidosis	4.9%
81	Ketonemia	4.9%
82	Vascular calcification	4.9%
83	Hypolipoproteinemias	4.9%
84	Hyperlipoproteinemia Type IV	4.8%
85	Hyperlipoproteinemia Type V	4.8%
86	Diabetes Mellitus	4.8%
87	Carbamoyl-Phosphate Synthase I Deficiency Disease	4.6%
88	Lactose Intolerance	4.6%
89	Dehydration	4.5%
90	Lipomatosis	4.5%
91	Water Intoxication	4.5%
92	Werner Syndrome	4.5%
93	Diabetic Ketoacidosis	4.5%
94	Hyperlipidemia, Familial Combined	4.5%
95	Achlorhydria	4.4%
96	Amino Acid Metabolism, Inborn Errors	4.4%
97	Bloom Syndrome	4.4%
98	Carbohydrate Metabolism, Inborn Errors	4.4%
99	Metal Metabolism, Inborn Errors	4.4%
100	Osteoporosis	4.4%
101	Progeria	4.4%
102	Lysosomal Storage Diseases	4.4%
103	Bone Demineralization, Pathologic	4.4%
104	Cytochrome-c Oxidase Deficiency	4.4%
105	Peroxisomal Disorders	4.4%
106	Post-Traumatic Osteoporosis	4.4%
107	Celiac Disease	4.4%
108	Sprue, Tropical	4.4%
109	Steatorrhea	4.4%
110	Sprue	4.4%
111	Hyperlipoproteinemia Type III	4.2%
112	Smith-Lemli-Opitz Syndrome	4.2%
113	Galactosemias	4.2%
114	Urea Cycle Disorders, Inborn	4.2%
115	Tyrosinemias	4.2%
116	Hypercholesterolemia	4.1%
117	Hyperlipoproteinemias	4.1%
118	Hypertriglyceridemia	4.1%
119	Congenital Hyperinsulinism	4.1%
120	Hypoalphalipoproteinemias	4%
121	Mitochondrial Encephalomyopathies	3.8%
122	Gaucher Disease	3.6%
123	Hyperphosphaturia	3.6%
124	Glycogen storage disease type II	3.5%
125	Homocystinuria	3.5%
126	Mitochondrial Myopathies	3.4%
127	Myelinolysis, Central Pontine	3.4%
128	Glycosuria	3.3%
129	Reye Syndrome	3.3%
130	Acidosis, Respiratory	3.3%
131	Adiposis Dolorosa	3.3%
132	Alkalosis, Respiratory	3.3%
133	Hepatic Encephalopathy	3.3%
134	Tay-Sachs Disease	3.3%
135	Nesidioblastosis	3.3%
136	Alkaptonuria	3.3%
137	Glycogen Storage Disease	3.3%
138	Hypophosphatasia	3.3%
139	Insulin Resistance	3.3%
140	Osteoporosis, Postmenopausal	3.3%
141	Propionic acidemia	3.3%
142	Dihydropyrimidine Dehydrogenase Deficiency	3.3%
143	Cystinosis	3.3%
144	Amyloid Neuropathies, Familial	3.3%
145	Renal tubular acidosis	3.2%
146	Niemann-Pick Disease, Type C	3.1%
147	Neuronal Ceroid-Lipofuscinoses	3%
148	Fabry Disease	2.8%
149	HIV-Associated Lipodystrophy Syndrome	2.8%
150	MELAS Syndrome	2.7%
151	Porphyrias, Hepatic	2.7%
152	Glycogen Storage Disease Type I	2.7%
153	Glycogen Storage Disease Type V	2.7%
154	Zellweger Syndrome	2.7%
155	Mucopolysaccharidosis III	2.7%
156	Adrenoleukodystrophy	2.7%
157	Necrobiosis Lipoidica Diabeticorum	2.6%
158	Menkes Kinky Hair Syndrome	2.6%
159	Fanconi Anemia	2.6%
160	Gestational Diabetes	2.6%
161	Latent Autoimmune Diabetes in Adults	2.6%
162	Diabetes Mellitus, Experimental	2.5%
163	Hepatolenticular Degeneration	2.5%
164	Nephrocalcinosis	2.5%
165	Tetany	2.5%
166	Refsum Disease	2.4%
167	Glycosuria, Renal	2.4%
168	Cerebral Amyloid Angiopathy	2.4%
169	Friedreich Ataxia	2.2%
170	Familial Periodic Paralysis	2%
171	Primary amyloidosis	2%
172	Variegate Porphyria	2%
173	Acute intermittent porphyria	2%
174	Porphyria Cutanea Tarda	2%
175	Renal Aminoacidurias	1.9%
176	Fanconi Syndrome	1.9%
177	Pseudohypoaldosteronism	1.9%
178	Liddle Syndrome	1.9%
179	Kernicterus	1.9%
180	Kearns-Sayre syndrome	1.9%
181	Cockayne Syndrome	1.9%
182	Canavan Disease	1.8%
183	Alexander Disease	1.8%
184	Sjogren-Larsson Syndrome	1.8%
185	Mucopolysaccharidosis II	1.8%
186	Ataxia Telangiectasia	1.7%
187	Gout	1.7%
188	Amyotrophic Lateral Sclerosis	1.7%
189	Optic Atrophy, Hereditary, Leber	1.6%
190	Antley-Bixler Syndrome Phenotype	1.6%
191	Hypokalemic periodic paralysis	1.6%
192	Frontotemporal dementia	1.6%
193	Cystinuria	1.6%
194	Xeroderma Pigmentosum	1.5%
195	CREST Syndrome	1.4%
196	Arthritis, Gouty	1.4%
197	Albinism	1.2%
198	Ichthyosis, X-Linked	1%

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