MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Dysentery

(UMLS:C0013369)

Definition:: Acute inflammation of the intestine associated with infectious DIARRHEA of various etiologies, generally acquired by eating contaminated food containing TOXINS, BIOLOGICAL derived from BACTERIA or other microorganisms. Dysentery is characterized initially by watery FECES then by bloody mucoid stools. It is often associated with ABDOMINAL PAIN; FEVER; and DEHYDRATION.
UMLS ID:: C0013369
MeSH ID:: D004403

Classification:

Name:

Digestive System Diseases
MeSH Tree Number(s):: C06.405.205.331|C06.405.469.300

Synonym(s)

Dysentery

DYSENTERY

Diarrhoea infectious

Dysentery, NOS

Infectious diarrhea

Infectious diarrheal disease

Infectious diarrheal disease, NOS

Infectious diarrhoea

Infectious diarrhoeal disease, NOS

10.

Infective diarrhea

11.

Infective diarrhoea

12.

diarrhea; infectious

13.

dysenteries

14.

dysentery

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Metformin	FAERS: 24		US FAERS
2	Sunitinib	FAERS: 24		US FAERS
3	Rivastigmine	FAERS: 23		US FAERS
4	Metformin	FAERS: 12		US FAERS
5	Aripiprazole	FAERS: 7		US FAERS
6	Deferasirox	FAERS: 7		US FAERS
7	Ibuprofen	FAERS: 7		US FAERS
8	Levofloxacin	FAERS: 7		US FAERS
9	Thyroxine	FAERS: 7		US FAERS
10	Zoledronic Acid	FAERS: 7 Canada Vigilance: 2		Canada Vigilance US FAERS
11	ambrisentan	FAERS: 7		US FAERS
12	Epoprostenol	FAERS: 6		US FAERS
13	pazopanib	FAERS: 6		US FAERS
14	Amoxicillin	FAERS: 5		US FAERS
15	Ciprofloxacin	FAERS: 5		US FAERS
16	Fluorouracil	FAERS: 5		US FAERS
17	Glatiramer Acetate	FAERS: 5		US FAERS
18	Olanzapine	FAERS: 5		US FAERS
19	Teriparatide	FAERS: 5		US FAERS
20	Azithromycin	FAERS: 4		US FAERS
21	Dimethyl Fumarate	FAERS: 4		US FAERS
22	Fingolimod Hydrochloride	FAERS: 4		US FAERS
23	Imatinib Mesylate	FAERS: 4		US FAERS
24	Lansoprazole	FAERS: 4		US FAERS
25	Tadalafil	FAERS: 4		US FAERS
26	Varenicline	FAERS: 4		US FAERS
27	teriflunomide	FAERS: 4		US FAERS
28	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 3		US FAERS
29	Carbamazepine	FAERS: 3		US FAERS
30	Celecoxib	FAERS: 3		US FAERS
31	Clarithromycin	FAERS: 3		US FAERS
32	HhAntag691	FAERS: 3		US FAERS
33	Lenalidomide	FAERS: 3		US FAERS
34	Octreotide	FAERS: 3		US FAERS
35	Pregabalin	FAERS: 3		US FAERS
36	Ticagrelor	FAERS: 3		US FAERS
37	apremilast	FAERS: 3		US FAERS
38	miglustat	FAERS: 3		US FAERS
39	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 2		US FAERS
40	Alprazolam	FAERS: 2		US FAERS
41	Anastrozole	FAERS: 2		US FAERS
42	Atorvastatin	FAERS: 2		US FAERS
43	Clopidogrel	FAERS: 2		US FAERS
44	Mebendazole	FAERS: 2		US FAERS
45	PCI 32765	FAERS: 2 Canada Vigilance: 1		Canada Vigilance US FAERS
46	Pantoprazole	FAERS: 2		US FAERS
47	Ramipril	FAERS: 2		US FAERS
48	Thyroxine	FAERS: 2		US FAERS
49	fluticasone furoate	FAERS: 2		US FAERS
50	pirfenidone	FAERS: 2		US FAERS
51	treprostinil	FAERS: 2		US FAERS
52	4-Aminopyridine	FAERS: 1		US FAERS
53	5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydron;chloride	FAERS: 1		US FAERS
54	Acetaminophen	FAERS: 1		US FAERS
55	Acyclovir	FAERS: 1		US FAERS
56	Afatinib	FAERS: 1		US FAERS
57	Amoxicillin-Potassium Clavulanate Combination	FAERS: 1		US FAERS
58	Atazanavir Sulfate	FAERS: 1		US FAERS
59	Axitinib	FAERS: 1		US FAERS
60	Bortezomib	FAERS: 1		US FAERS
61	Bosentan	FAERS: 1		US FAERS
62	Budesonide	FAERS: 1		US FAERS
63	Cabozantinib S-malate	FAERS: 1		US FAERS
64	Capecitabine	FAERS: 1		US FAERS
65	Ceftriaxone	FAERS: 1		US FAERS
66	Cinacalcet	FAERS: 1		US FAERS
67	Ciprofloxacin	FAERS: 1		US FAERS
68	Clopidogrel	FAERS: 1		US FAERS
69	Desvenlafaxine Succinate	FAERS: 1		US FAERS
70	Diazepam	FAERS: 1		US FAERS
71	Diclofenac	FAERS: 1		US FAERS
72	Diclofenac	FAERS: 1		US FAERS
73	Diovan Hct	FAERS: 1		US FAERS
74	Duloxetine Hydrochloride	FAERS: 1		US FAERS
75	Erlotinib Hydrochloride	FAERS: 1		US FAERS
76	Fexofenadine hydrochloride and pseudoephedrine hydrochloride	FAERS: 1		US FAERS
77	Fosfomycin	FAERS: 1		US FAERS
78	Gefitinib	FAERS: 1		US FAERS
79	Ibandronic Acid	FAERS: 1		US FAERS
80	LCZ 696	FAERS: 1		US FAERS
81	Lapatinib	FAERS: 1		US FAERS
82	Leflunomide	FAERS: 1		US FAERS
83	Levetiracetam	FAERS: 1		US FAERS
84	Liraglutide	FAERS: 1		US FAERS
85	Loperamide	FAERS: 1		US FAERS
86	Loperamide	FAERS: 1		US FAERS
87	MDV 3100	FAERS: 1		US FAERS
88	Medroxyprogesterone Acetate	FAERS: 1		US FAERS
89	Meloxicam	FAERS: 1		US FAERS
90	Methotrexate	FAERS: 1		US FAERS
91	Methylphenidate	FAERS: 1		US FAERS
92	Metronidazole	FAERS: 1		US FAERS
93	Omeprazole	FAERS: 1		US FAERS
94	Omeprazole	FAERS: 1		US FAERS
95	Paliperidone Palmitate	FAERS: 1		US FAERS
96	Piperacillin/tazobactam	FAERS: 1		US FAERS
97	Propafenone	FAERS: 1		US FAERS
98	Quetiapine Fumarate	FAERS: 1		US FAERS
99	Rabeprazole	FAERS: 1		US FAERS
100	Rifampin	FAERS: 1		US FAERS
101	Rivaroxaban	FAERS: 1		US FAERS
102	Rosuvastatin Calcium	FAERS: 1		US FAERS
103	Ruxolitinib phosphate	FAERS: 1		US FAERS
104	Senna Extract	FAERS: 1		US FAERS
105	Sertraline	FAERS: 1		US FAERS
106	Sorafenib	FAERS: 1		US FAERS
107	Tenofovir	FAERS: 1		US FAERS
108	Triamcinolone Acetonide	FAERS: 1		US FAERS
109	Triumeq	FAERS: 1		US FAERS
110	Verteporfin	FAERS: 1		US FAERS
111	Warfarin	FAERS: 1		US FAERS
112	aliskiren	FAERS: 1		US FAERS
113	atovaquone, proguanil drug combination	FAERS: 1		US FAERS
114	bosutinib	FAERS: 1		US FAERS
115	cefuroxime axetil	FAERS: 1		US FAERS
116	idelalisib	FAERS: 1		US FAERS
117	mirabegron	FAERS: 1		US FAERS
118	nintedanib	FAERS: 1		US FAERS
119	pimecrolimus	FAERS: 1		US FAERS
120	trametinib	FAERS: 1		US FAERS
121	Nalidixic Acid		10063299	CTD
122	Orlistat			SIDER
123	Rifaximin			SIDER
124	Saquinavir			SIDER
125	ropinirole			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Enteritis	66.7%
2	Enterocolitis	66.7%
3	Inflammatory Bowel Diseases	66.7%
4	Proctocolitis	62.4%
5	Duodenitis	58.8%
6	Ileitis	58.8%
7	Erosive Duodenitis	58.8%
8	Colitis	57.9%
9	Proctitis	57.9%
10	Esophagitis	53.3%
11	Gastritis	53.3%
12	Zollinger-Ellison syndrome	51%
13	Crohn Disease	49.2%
14	Duodenal Obstruction	49.2%
15	Enterocolitis, Neutropenic	49.2%
16	Necrotizing Enterocolitis	49.2%
17	Pouchitis	48.5%
18	Appendicitis	46.4%
19	Colorectal Neoplasms	46.2%
20	Duodenogastric Reflux	44.6%
21	Peptic Ulcer	44.6%
22	Cecal Diseases	44.4%
23	Colonic Diseases	44.4%
24	Ileal Diseases	44.4%
25	Intestinal Obstruction	44.4%
26	Intestinal Perforation	44.4%
27	Jejunal Diseases	44.4%
28	Pneumatosis Cystoides Intestinalis	44.4%
29	Rectal Diseases	44.4%
30	Cronkhite-Canada Syndrome	44.4%
31	Intestinal Polyposis	44.4%
32	Esophageal Diseases	40.9%
33	Stomach Diseases	40.9%
34	Intestinal Neoplasms	39.8%
35	Enterocolitis, Pseudomembranous	39.2%
36	pseudomembranous colitis	39.2%
37	Cecal Neoplasms	39%
38	Duodenal Neoplasms	39%
39	Colonic Pseudo-Obstruction	38.5%
40	Rectal Fistula	37.1%
41	Anal Fistula	37.1%
42	Colitis, Ischemic	36.5%
43	Mesenteric vascular insufficiency	35.6%
44	Anus Neoplasms	35.1%
45	Sigmoid Neoplasms	35.1%
46	Intestinal Atresia	35.1%
47	Mesenteric Vascular Occlusion	35.1%
48	Duodenal Ulcer	35.1%
49	Peptic Ulcer Perforation	35.1%
50	Gastric ulcer	35.1%
51	Intestinal Diseases, Parasitic	35.1%
52	Intestinal Fistula	34.9%
53	Enterocutaneous Fistula	34.9%
54	Colonic Diseases, Functional	33%
55	Fecal Incontinence	33%
56	Fecal Impaction	33%
57	Intussusception	33%
58	Megacolon	33%
59	Ileus	33%
60	Meconium ileus	33%
61	Gastrointestinal Neoplasms	32.9%
62	Appendiceal Neoplasms	32.1%
63	Colonic Neoplasms	32.1%
64	Rectal Neoplasms	32.1%
65	Stomach Neoplasms	30.9%
66	Gastrointestinal Hemorrhage	30.5%
67	Tuberculosis, Gastrointestinal	30.1%
68	Adenomatous Polyposis Coli	29.6%
69	Anal Fissure	27.3%
70	Intestinal Pseudo-Obstruction	27.3%
71	Irritable Bowel Syndrome	27.3%
72	Superior Mesenteric Artery Syndrome	27.3%
73	Neurogenic Bowel	27.3%
74	Anal Ulcer	27.3%
75	Esophageal and Gastric Varices	26.7%
76	Esophageal Stenosis	26.7%
77	Gastric Dilatation	26.7%
78	Gastric outlet obstruction	26.7%
79	Esophageal Neoplasms	26.5%
80	Hemorrhoids	25.2%
81	Afferent Loop Syndrome	24.8%
82	Celiac Disease	24.8%
83	Short Bowel Syndrome	24.8%
84	Sprue, Tropical	24.8%
85	Steatorrhea	24.8%
86	Rectocele	24.8%
87	Sprue	24.8%
88	Diverticulitis	24.6%
89	Rectal Prolapse	24.6%
90	Esophageal Atresia	24.3%
91	Biliary Tract Diseases	23.8%
92	Liver diseases	23.8%
93	Pancreatic Diseases	23.8%
94	Gastrointestinal Stromal Tumors	21.2%
95	Esophageal Perforation	21.1%
96	Pruritus Ani	20.6%
97	Gastroenteritis	20.5%
98	Intestinal Diseases	20.5%
99	Giardiasis	20.4%
100	Barrett Esophagus	20.3%
101	Deglutition Disorders	20.3%
102	Achlorhydria	20%
103	Diverticulum	20%
104	Dysentery	20%
105	Gastric Antral Vascular Ectasia	20%
106	Diverticulosis	20%
107	Peptic Ulcer Hemorrhage	19.8%
108	Gastroparesis	19.8%
109	Esophageal motility disorders	19.8%
110	Mallory-Weiss Syndrome	19.8%
111	Pyloric Stenosis	19.8%
112	Digestive System Neoplasms	17.9%
113	Peutz-Jeghers Syndrome	16.6%
114	Liver neoplasms	16.4%
115	Esophageal Achalasia	16.4%
116	Lactose Intolerance	16.4%
117	Pancreatic Fistula	16.3%
118	Melena	16.1%
119	Hematemesis	15.8%
120	Dumping Syndrome	14.8%
121	Biliary cirrhosis	13.9%
122	Bile Duct Diseases	13.6%
123	Cholelithiasis	13.6%
124	Chylous Ascites	13.6%
125	Fatty Liver	13.6%
126	Hepatitis	13.6%
127	Portal Hypertension	13.6%
128	Liver Cirrhosis	13.6%
129	Pancreatic Insufficiency	13.6%
130	Pancreatitis	13.6%
131	Peritoneal Neoplasms	13.6%
132	Pneumoperitoneum	13.6%
133	Focal Nodular Hyperplasia	13.6%
134	Hepatic Insufficiency	13.6%
135	Steatohepatitis	13.6%
136	Cholecystolithiasis	13.3%
137	Bile Duct Neoplasms	13.3%
138	gallbladder neoplasm	13.3%
139	Cryptosporidiosis	12.6%
140	Pancreatic Neoplasm	11.8%
141	Dysentery, Bacillary	11.8%
142	Choledocholithiasis	11.6%
143	Choledochal Cyst	11.4%
144	Laryngopharyngeal Reflux	11.3%
145	Liver Diseases, Parasitic	10.7%
146	Fatty Liver, Alcoholic	10.6%
147	Hepatitis, Alcoholic	10.6%
148	Liver Cirrhosis, Alcoholic	10.6%
149	Hepatic Veno-Occlusive Disease	10.3%
150	Pancreatic Cyst	10.3%
151	Peliosis Hepatis	10.3%
152	Hepatopulmonary Syndrome	10.3%
153	Anus, Imperforate	10.2%
154	Hemoperitoneum	10.2%
155	Hepatomegaly	10.2%
156	Mesenteric Panniculitis	10.2%
157	Panniculitis, Peritoneal	10.2%
158	Peritonitis	10.2%
159	Peritoneal Fibrosis	10.2%
160	Encapsulating Peritoneal Sclerosis	10.2%
161	Anorectal Malformations	10.2%
162	Biliary Fistula	10.1%
163	Gastric Fistula	10.1%
164	Hepatic Vein Thrombosis	10%
165	Liver Abscess	10%
166	Budd-Chiari Syndrome	10%
167	Cholangitis	8.9%
168	Cholecystitis	8.9%
169	Cholestasis	8.9%
170	Common Bile Duct Diseases	8.9%
171	Hepatitis, Chronic	8.9%
172	Liver Failure	8.9%
173	Pancreatitis, Chronic	8.9%
174	Non-alcoholic Fatty Liver Disease	8.9%
175	Chronic active hepatitis	8.9%
176	Hepatocellular Adenoma	8.8%
177	Chemical and Drug Induced Liver Injury	8.3%
178	Hepatorenal Syndrome	8.1%
179	Liver Abscess, Amebic	7.6%
180	Liver Neoplasms, Experimental	7.6%
181	Hepatitis, Animal	7%
182	Hepatitis, Viral, Human	7%
183	Cystic Fibrosis	7%
184	Porphyrias, Hepatic	6.7%
185	Congenital Hyperinsulinism	6.7%
186	Liver Cirrhosis, Experimental	6.7%
187	Pancreatic Pseudocyst	6.7%
188	Pancreatitis, Alcoholic	6.6%
189	Cholestasis, Extrahepatic	6.6%
190	Biliary Dyskinesia	6.6%
191	Cholangitis, Sclerosing	6.6%
192	Liver Failure, Acute	6.6%
193	Acalculous Cholecystitis	6.6%
194	End Stage Liver Disease	6.6%
195	CREST Syndrome	6.1%
196	Hepatitis B, Chronic	6%
197	Hepatitis C, Chronic	6%
198	Carcinoma, Pancreatic Ductal	5.8%
199	Massive Hepatic Necrosis	5.5%
200	Emphysematous Cholecystitis	5.5%
201	Sphincter of Oddi Dysfunction	5.5%
202	Fascioliasis	5.4%
203	Echinococcosis, Hepatic	5.4%
204	Chemical and Drug Induced Liver Injury, Chronic	5.3%
205	Reye Syndrome	5.3%
206	Autoimmune hepatitis	5%
207	insulinoma	4.8%
208	Gastrinoma	4.8%
209	Glucagonoma	4.8%
210	Nesidioblastosis	4.4%
211	Variegate Porphyria	4.4%
212	Acute intermittent porphyria	4.4%
213	Porphyria Cutanea Tarda	4.4%
214	Vipoma	4.3%
215	Hepatitis, Viral, Animal	4.2%
216	Hepatitis E	4.1%
217	Hepatitis B	4%
218	Hepatitis C	4%
219	Hepatitis A	4%
220	Hepatic Encephalopathy	3.9%
221	Zellweger Syndrome	3.3%
222	Hepatolenticular Degeneration	3%
223	Rift Valley Fever	2.1%

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