MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Aortitis

(UMLS:C0003509)

Definition:: Inflammation of the wall of the AORTA.
UMLS ID:: C0003509
MeSH ID:: D001025

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.109.320|C14.907.940.080

Synonym(s)

Aortitis

Aortic vasculitis

Aortitis, NOS

aortitis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Metformin	FAERS: 14		US FAERS
2	Sunitinib	FAERS: 5		OFFSIDES US FAERS
3	Metformin	FAERS: 3		US FAERS
4	Citalopram	FAERS: 2		US FAERS
5	Teriparatide	FAERS: 2		US FAERS
6	Tretinoin	FAERS: 2		OFFSIDES US FAERS
7	Azacitidine	FAERS: 1		US FAERS
8	Bisoprolol	FAERS: 1		US FAERS
9	Dronedarone	FAERS: 1		US FAERS
10	Mesalamine	FAERS: 1		US FAERS
11	Methotrexate	FAERS: 1		US FAERS
12	Voriconazole	FAERS: 1		US FAERS
13	eltrombopag	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
14	entecavir	FAERS: 1		US FAERS
15	rofecoxib	FAERS: 1		US FAERS
16	tofacitinib	FAERS: 1		US FAERS
17	Capecitabine			OFFSIDES
18	Darunavir			OFFSIDES
19	Docetaxel		20407388	CTD
20	Furosemide		6546667	CTD
21	Sunitinib			OFFSIDES
22	Tenofovir			OFFSIDES
23	Triazolam			OFFSIDES
24	bismuth subsalicylate			OFFSIDES
25	chlordiazepoxide, clidinium drug combination			OFFSIDES
26	gemcitabine		20407388	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Aortic Aneurysm	53.3%
2	Leriche Syndrome	53.3%
3	Periphlebitis	53.3%
4	Phlebitis	53.3%
5	Thromboangiitis Obliterans	53.3%
6	Arteritis	44.4%
7	Systemic Vasculitis	44.4%
8	Malignant Atrophic Papulosis	42.7%
9	Shwartzman Phenomenon	42.4%
10	Myocardial Ischemia	41.4%
11	Thrombophlebitis	41%
12	Aneurysm	40.9%
13	Angiomatosis	40.9%
14	Arterial Occlusive Diseases	40.9%
15	Hyperemia	40.9%
16	Hypotension	40.9%
17	Superior Vena Cava Syndrome	40.9%
18	Telangiectasis	40.9%
19	Venous Insufficiency	40.9%
20	Peripheral Vascular Diseases	40.9%
21	Embolism and Thrombosis	40.9%
22	Angiodysplasia	40.9%
23	Capillary Leak Syndrome	40.9%
24	Prehypertension	40.9%
25	Polyarteritis Nodosa	39.5%
26	Takayasu Arteritis	39.5%
27	Aortic Aneurysm, Abdominal	39.3%
28	Aortic Aneurysm, Thoracic	39.3%
29	Aortic Rupture	36.5%
30	Postphlebitic Syndrome	34.7%
31	Retinal Vein Occlusion	34.6%
32	Retinal Vasculitis	33.9%
33	Vasculitis, Leukocytoclastic, Cutaneous	33.3%
34	Endarteritis	33%
35	Vascular System Injuries	32.1%
36	Coronary Aneurysm	31.6%
37	Compartment syndromes	31%
38	Hepatic Veno-Occlusive Disease	31%
39	Peliosis Hepatis	31%
40	Varicocele	31%
41	Blue Toe Syndrome	30.8%
42	Vasculitis, Central Nervous System	30.6%
43	Cerebrovascular Disorders	30.5%
44	Diabetic Angiopathies	30.5%
45	Reperfusion Injury	30.5%
46	Splenic Infarction	30.5%
47	Cerebrovascular Insufficiency	30.5%
48	Vascular Neoplasms	30.5%
49	Spinal Cord Vascular Diseases	30.5%
50	Vasoplegia	30.5%
51	Myocardial Reperfusion Injury	30.3%
52	Hemorrhoids	30.3%
53	Thoracic Outlet Syndrome	30.3%
54	Giant Cell Arteritis	28.3%
55	Temporal Arteritis	28.3%
56	Intracranial Embolism and Thrombosis	27.6%
57	Carotid Artery Thrombosis	27.6%
58	Carotid Stenosis	27.5%
59	Intracranial Aneurysm	27.5%
60	Coronary Thrombosis	27.5%
61	Coronary Artery Disease	27.5%
62	Mucocutaneous Lymph Node Syndrome	27%
63	Aneurysm, Dissecting	26.7%
64	Arteriosclerosis	26.7%
65	Coronary heart disease	26.7%
66	Embolism	26.7%
67	Erythromelalgia	26.7%
68	Fibromuscular Dysplasia	26.7%
69	Malignant Hypertension	26.7%
70	Myocardial Infarction	26.7%
71	Raynaud Disease	26.7%
72	Thromboembolism	26.7%
73	Thrombosis	26.7%
74	Essential Hypertension	26.7%
75	Aneurysm, Ruptured	26.7%
76	Iliac Aneurysm	26.7%
77	Pulmonary artery stenosis	26.7%
78	White Coat Hypertension	26.7%
79	Acute Coronary Syndrome	26.7%
80	Embolus	26.7%
81	Moyamoya Disease	26.4%
82	Hand-Arm Vibration Syndrome	25.4%
83	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	25.2%
84	Optic Neuropathy, Ischemic	24.7%
85	Anterior Ischemic Optic Neuropathy	24.7%
86	Mesenteric vascular insufficiency	24.7%
87	Arteriovenous fistula	24.5%
88	Angioedema	24%
89	Colitis, Ischemic	23.9%
90	Heart Diseases	23.8%
91	Intracranial Arteriosclerosis	23.5%
92	Cerebral Atherosclerosis	23.5%
93	Cerebral Arteriosclerosis	23.5%
94	Lemierre Syndrome	22.1%
95	Kounis Syndrome	21.6%
96	Cerebral Thrombosis	21.4%
97	Intracranial Embolism	21.4%
98	Intracranial Thrombosis	21.4%
99	May-Thurner Syndrome	21.2%
100	Angina Pectoris	21.1%
101	Aortic Diseases	20.5%
102	Vasculitis	20.5%
103	Retinal Artery Occlusion	20.3%
104	Hypertensive Retinopathy	20.3%
105	Embolism, Amniotic Fluid	20.1%
106	Anterior Compartment Syndrome	20%
107	Aortitis	20%
108	Gastric Antral Vascular Ectasia	20%
109	Abdominal Compartment Syndrome	20%
110	Carotid Artery Diseases	19.8%
111	Brain Ischemia	19.8%
112	Hypotension, Orthostatic	19.8%
113	Cerebrovascular accident	19.8%
114	Varicose Ulcer	19.8%
115	Vasospasm, Intracranial	19.8%
116	Spinal Cord Ischemia	19.8%
117	Intracranial Arterial Diseases	19.8%
118	Primary Graft Dysfunction	19.8%
119	Post-Exercise Hypotension	19.8%
120	Arteriosclerosis Obliterans	19.8%
121	Atherosclerosis	19.8%
122	Air Embolism	19.8%
123	Venous Thrombosis	19.8%
124	Deep Vein Thrombosis	19.8%
125	Venous Thromboembolism	19.8%
126	Coronary Occlusion	19.7%
127	Microvascular Angina	19.7%
128	Coronary Stenosis	19.7%
129	ST segment elevation myocardial infarction	19.7%
130	Brain Infarction	19.5%
131	Scimitar Syndrome	18.7%
132	Sinus Thrombosis, Intracranial	18.4%
133	Pregnancy Complications, Cardiovascular	17.9%
134	Cardiovascular Abnormalities	17.9%
135	Subarachnoid Hemorrhage, Traumatic	17.2%
136	Carotid Artery, Internal, Dissection	17.2%
137	CREST Syndrome	17.1%
138	Cavernous Sinus Thrombosis	16.9%
139	Sagittal Sinus Thrombosis	16.9%
140	Vertebral Artery Dissection	16.9%
141	Infarction, Middle Cerebral Artery	16.8%
142	Infarction, Anterior Cerebral Artery	16.8%
143	Infarction, Posterior Cerebral Artery	16.8%
144	Behcet Syndrome	16.6%
145	Granulomatosis with polyangiitis	16.5%
146	Coronary Restenosis	16.3%
147	Mesenteric Vascular Occlusion	16.2%
148	Diabetic Retinopathy	16.1%
149	Sturge-Weber Syndrome	16.1%
150	Cerebral Infarction	16.1%
151	Brain Stem Infarctions	16.1%
152	Livedo Reticularis	16%
153	Renal hypertension	15.9%
154	Renal Artery Obstruction	15.9%
155	Renal Artery Stenosis	15.9%
156	Hemangioma, Cavernous	15.8%
157	Shock, Cardiogenic	15.8%
158	Basal Ganglia Cerebrovascular Disease	15.8%
159	Vascular Headaches	15.7%
160	Scurvy	15.7%
161	Angina, Unstable	15.6%
162	Intermittent Claudication	15.1%
163	Pulmonary Embolism	15.1%
164	No-Reflow Phenomenon	14.9%
165	Cerebral Arterial Diseases	14.7%
166	Vertebrobasilar Insufficiency	14.7%
167	Carotid Artery Injuries	14.7%
168	Anterior Spinal Artery Syndrome	14.7%
169	Basilar Artery Stenosis	14.7%
170	Vertebral Artery Stenosis	14.7%
171	Intracranial Hemorrhage, Hypertensive	14.7%
172	Transient Cerebral Ischemia	14.7%
173	Lateral Medullary Syndrome	14.4%
174	Rheumatoid Vasculitis	14.1%
175	Cardiac Tamponade	13.6%
176	Endocarditis	13.6%
177	Cardiac Arrest	13.6%
178	Heart failure	13.6%
179	Pericardial effusion	13.6%
180	Pericarditis	13.6%
181	Pneumopericardium	13.6%
182	Cor pulmonale	13.6%
183	Ventricular Outflow Obstruction	13.6%
184	Ventricular Dysfunction	13.6%
185	Cardiomyopathies	13.6%
186	Pleuropericarditis	13.6%
187	Aortic Valve Stenosis	13.3%
188	Cardiomyopathy, Dilated	13.3%
189	Pulmonary Valve Stenosis	13.3%
190	Ischemic contracture	13.3%
191	Basal Ganglia Hemorrhage	13.3%
192	Angioedemas, Hereditary	13.3%
193	Tricuspid Atresia	13.3%
194	Arrhythmogenic Right Ventricular Dysplasia	13.3%
195	Cryoglobulinemia	13.2%
196	Leukomalacia, Periventricular	13.2%
197	Diabetic Foot	13.1%
198	Angina Pectoris, Variant	12.9%
199	Hepatic Vein Thrombosis	12.6%
200	Budd-Chiari Syndrome	12.6%
201	Pulmonary Infarction	12.3%
202	Subclavian Steal Syndrome	12.2%
203	Lupus Vasculitis, Central Nervous System	12%
204	Hypertension, Renovascular	11.7%
205	Subarachnoid Hemorrhage	11.7%
206	Hypoxia-Ischemia, Brain	11.7%
207	Cerebral Hemorrhage	11.7%
208	Hereditary Angioedema Type III	11.7%
209	Hereditary Angioedema Types I and II	11.7%
210	Putaminal Hemorrhage	11.4%
211	Bacterial Endocarditis	11.4%
212	Shy-Drager Syndrome	11.2%
213	Purpura, Hyperglobulinemic	11.2%
214	Dementia, Vascular	10.8%
215	Hypertrophic Cardiomyopathy	10.7%
216	Hypertrophic obstructive cardiomyopathy	10.7%
217	Heart Block	10.7%
218	Tachycardia	10.7%
219	Tachyarrhythmia	10.7%
220	Aortic coarctation	10.6%
221	Cor Triatriatum	10.6%
222	Coronary Vessel Anomalies	10.6%
223	Patent ductus arteriosus	10.6%
224	Ebstein Anomaly	10.6%
225	Heart Septal Defects	10.6%
226	Tetralogy of Fallot	10.6%
227	Transposition of Great Vessels	10.6%
228	Hypoplastic Left Heart Syndrome	10.6%
229	Cardiac Output, High	10.3%
230	Myocardial Stunning	10.3%
231	Low Cardiac Output Syndrome	10.3%
232	Cardiomegaly	10.2%
233	Postpericardiotomy Syndrome	10.2%
234	Cardiac Hypertrophy	10.2%
235	Rheumatic Heart Disease	10%
236	Waldenstrom Macroglobulinemia	9.9%
237	Multiple Myeloma	9.9%
238	Pituitary Apoplexy	9.9%
239	Supravalvular aortic stenosis	9.8%
240	Lown-Ganong-Levine Syndrome	9.8%
241	Cerebral Amyloid Angiopathy	9.7%
242	Ataxia Telangiectasia	9%
243	Pseudoxanthoma Elasticum	8.9%
244	Aortic Valve Insufficiency	8.9%
245	Restrictive cardiomyopathy	8.9%
246	Endocardial Fibroelastosis	8.9%
247	Heart Rupture, Post-Infarction	8.9%
248	Mitral Valve Insufficiency	8.9%
249	Mitral Valve Stenosis	8.9%
250	Myocarditis	8.9%
251	Pericarditis, Constrictive	8.9%
252	Pulmonary Valve Insufficiency	8.9%
253	Tricuspid Valve Insufficiency	8.9%
254	Tricuspid Valve Stenosis	8.9%
255	Ventricular Dysfunction, Left	8.9%
256	Right Ventricular Dysfunction	8.9%
257	Endomyocardial Fibrosis	8.9%
258	Carditis	8.9%
259	Heart Failure, Systolic	8.9%
260	Heart Failure, Diastolic	8.9%
261	Dextrocardia	8.8%
262	Long QT Syndrome	8.8%
263	Sick Sinus Syndrome	8.4%
264	Adams-Stokes Syndrome	7.8%
265	Atrioventricular Block	7.8%
266	Bundle-Branch Block	7.8%
267	Atrial Premature Complexes	7.8%
268	Sinoatrial Block	7.8%
269	Tachycardia, Paroxysmal	7.8%
270	Supraventricular tachycardia	7.8%
271	Tachycardia, Ventricular	7.8%
272	Wolff-Parkinson-White Syndrome	7.8%
273	Tachycardia, Reciprocating	7.8%
274	Aortopulmonary Septal Defect	7.8%
275	Double Outlet Right Ventricle	7.8%
276	Endocardial Cushion Defects	7.8%
277	Myocardial bridging	7.8%
278	Aorticopulmonary Septal Defect	7.8%
279	Sinus Arrhythmia	6.7%
280	Atrial Fibrillation	6.7%
281	Atrial Flutter	6.7%
282	Edema, Cardiac	6.7%
283	Noonan Syndrome	6.7%
284	Ventricular Fibrillation	6.7%
285	Ventricular Flutter	6.7%
286	Parasystole	6.7%
287	Paroxysmal atrial fibrillation	6.7%
288	Bradycardia	6.7%
289	Diabetic Cardiomyopathies	6.7%
290	Cardiomyopathy, Alcoholic	6.6%
291	Ectopia Cordis	6.6%
292	Sudden Cardiac Death	6.6%
293	Left Ventricular Hypertrophy	6.6%
294	Right Ventricular Hypertrophy	6.6%
295	Single umbilical artery	6.6%
296	Aortic Valve Prolapse	6.6%
297	Tricuspid Valve Prolapse	6.6%
298	Takotsubo Cardiomyopathy	6.6%
299	Chagas Cardiomyopathy	6.6%
300	Subacute Bacterial Endocarditis	6.6%
301	Carcinoid Heart Disease	6.5%
302	Romano-Ward Syndrome	6.5%
303	Tachycardia, Atrioventricular Nodal Reentry	6.5%
304	Tachycardia, Ectopic Atrial	6.5%
305	Tachycardia, Ectopic Junctional	6.5%
306	Sinus Tachycardia	6.5%
307	Torsades de Pointes	6.5%
308	Accelerated Idioventricular Rhythm	6.5%
309	Truncus Arteriosus, Persistent	6.5%
310	Hematoma, Subdural	6.1%
311	Hematoma, Epidural, Cranial	6.1%
312	Marfan Syndrome	6%
313	Hematoma, Subdural, Intracranial	5.4%
314	Hematoma, Subdural, Chronic	5.4%
315	Hematoma, Subdural, Acute	5.4%
316	Brain Hemorrhage, Traumatic	5.4%
317	Dyspnea, Paroxysmal	5.3%
318	MELAS Syndrome	5.3%
319	Sinus Arrest, Cardiac	4.9%
320	Dural Arteriovenous Fistula	4.5%
321	Fabry Disease	4.1%
322	Turner Syndrome	3.4%
323	Kartagener Syndrome	2.9%
324	Williams Syndrome	2.7%
325	Kearns-Sayre syndrome	2.2%

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