MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

anaphylaxis

(UMLS:C0002792)

Definition:: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.
UMLS ID:: C0002792
MeSH ID:: D000707

Classification:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.480.099

Synonym(s)

anaphylaxis

ANAPHYLAXIS

Allergic shock

Anaphylactic Reaction

Anaphylactic reaction

Anaphylactic shock

Anaphylactic syndrome

Anaphylaxis

Anaphylaxis, generalized

10.

Generalized anaphylaxis

Associated Drug(s)

	Name	Reference(s)	Data Source
1	3,3',4,5'-tetrahydroxystilbene	23426871	CTD
2	Acetaminophen	1422939 19008617	CTD
3	Acetylcysteine	1355236 6234965	CTD
4	Albuterol	12637407 16101941	CTD
5	Alcuronium	7976160	CTD
6	Allopurinol	7634908	CTD
7	Aminopyrine	65671	CTD
8	Amoxicillin	View details 8092427 10439663 15005775 15301308	CTD
9	Ampicillin	3954915	CTD
10	Aspirin	View details 6475695 7731260 10400483 18089939	CTD
11	Atracurium	7976160	CTD
12	Betamethasone	8629796	CTD
13	Bleomycin	65671	CTD
14	Capsaicin	20441089	CTD
15	Carbenicillin	65671	CTD
16	Carboxymethylcellulose Sodium	1938768	CTD
17	Cefaclor	24329898	CTD
18	Cefotaxime	9915680	CTD
19	Cefoxitin	6486149 10204595 15881565	CTD
20	Ceftriaxone	14993721	CTD
21	Cefuroxime	2774306	CTD
22	Celecoxib	11476468	CTD
23	Cephalothin	65671	CTD
24	Chlorhexidine	1560587 27039991	CTD
25	Chlorpheniramine	12632613 12637407	CTD
26	Cimetidine	2774306 21461253	CTD
27	Cinoxacin	12674041	CTD
28	Clemastine	16101941	CTD
29	Cocaine	10425061	CTD
30	Cromolyn Sodium	9597688 16536907 24361550	CTD
31	Cyclizine	5762012	CTD
32	Diatrizoate Meglumine	5279372	CTD
33	Diatrizoate	1147448	CTD
34	Diclofenac	9220183 12975044	CTD
35	Dipyridamole	7977438	CTD
36	Docetaxel	7918126 12006518	CTD
37	Epinephrine	View details 8498731 9972775 11476468 12009227 12637407 15701770 16101941 16545221 17324313 17460744 19720784 20461973 20726206	CTD
38	Ethambutol	8643939	CTD
39	FS 069	15488089	CTD
40	Famotidine	12632613 20461973	CTD
41	Fentanyl	17400983	CTD
42	Gallamine Triethiodide	7976160	CTD
43	Hydrocortisone	12637407 15701770	CTD
44	Hydroxocobalamin	4815245 5572387	CTD
45	Ibuprofen	9532969 19482364	CTD
46	Ifosfamide	3132591	CTD
47	Indomethacin	9220183	CTD
48	Iohexol	12009227 16518532	CTD
49	Iopamidol	2923308	CTD
50	Isoniazid	10066642	CTD
51	Itraconazole	19261964	CTD
52	Ketoconazole	15701770 18277890	CTD
53	Lamivudine	8942805	CTD
54	Lansoprazole	12464168	CTD
55	Lidoderm	2806083 14688599	CTD
56	Losartan	20726206	CTD
57	Mesalamine	11906377	CTD
58	Methotrexate	6582805 8569964	CTD
59	Miconazole	7436161	CTD
60	Morphine	2471936	CTD
61	Naloxone	2471936	CTD
62	Nitroglycerin	20084849	CTD
63	Olopatadine Hydrochloride	8951675	CTD
64	Omeprazole	9988207 12681212 16397810	CTD
65	Oxytocin	8517515	CTD
66	Paclitaxel	7509380 7524159	CTD
67	Pancuronium	9785081	CTD
68	Penicillin G	65671	CTD
69	Prednisone	1147448	CTD
70	Propanidid	5762012 6161470	CTD
71	Propofol	11480255	CTD
72	Resveratrol	22962611 23514766	CTD
73	Rifampin	10066642	CTD
74	Rocuronium	12066744 21414980	CTD
75	Sodium Benzoate	1674808	CTD
76	Streptomycin	5041698	CTD
77	Succinylcholine	View details 1897443 2917103 6165498 7002360 7976160 8533551 10422386 18829243 19535703	CTD
78	Sulfasalazine	1972633 9597688	CTD
79	Sulindac	6731964	CTD
80	Teniposide	4609765	CTD
81	Tetracycline	848727	CTD
82	Thiethylperazine	16101941	CTD
83	Thiopental	View details 1166949 1897443 2917103 4654818 5550850 9105248	CTD
84	Timolol	8378620	CTD
85	Trichloroethylene	22467029	CTD
86	Trimethoprim, Sulfamethoxazole Drug Combination	20046017	CTD
87	Tubocurarine	7976160	CTD
88	Vancomycin	3986655	CTD
89	Vecuronium Bromide	7976160 8533551	CTD
90	Vincristine	19018221	CTD
91	Vitamin B 12	5572387	CTD
92	benoxinate	10917687	CTD
93	chlorhexidine gluconate	10321611	CTD
94	chrysin	21515303	CTD
95	cisatracurium	9972775 18570839 19097966	CTD
96	dichloralantipyrine	2060257	CTD
97	doqualast	2434109	CTD
98	galangin	23535185	CTD
99	gemcitabine	12006518	CTD
100	isoniazid, pyrazinamide, rifampin drug combination	8643939	CTD
101	mangiferin	14669257 16536907	CTD
102	methyleugenol	9125128	CTD
103	naringin	24131540	CTD
104	p-Methoxy-N-methylphenethylamine	View details 9125128 9597688 21515303 23426871 24131540 24361550	CTD
105	polydatin	22959927	CTD
106	reviparin	15299161 19702217	CTD
107	urovision	2074636	CTD
108	ziprasidone	19653983	CTD
109	zomepirac	View details 4073114 6731466 7057609 29154782	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Food Allergy	46.7%
2	Milk Allergy	34.4%
3	Wheat Hypersensitivity	34.4%
4	Respiratory Hypersensitivity	33.3%
5	Urticaria	31.1%
6	Immune Complex Diseases	31%
7	Latex allergy	31%
8	Asthma, Aspirin-Induced	22.2%
9	Environmental Illness	22%
10	Autoimmune Diseases	18.5%
11	Immunologic Deficiency Syndromes	18.5%
12	Immunoproliferative Disorders	18.5%
13	Immune reconstitution syndrome	18.5%
14	Immune Reconstitution Inflammatory Syndrome	18.5%
15	Angioedema	17.5%
16	Dermatitis, Atopic	15.6%
17	Kounis Syndrome	15.3%
18	Asthma, Exercise-Induced	14.4%
19	Status Asthmaticus	14.4%
20	Asthma	14.3%
21	Serum Sickness	13.7%
22	Sick Building Syndrome	13.6%
23	Multiple Chemical Sensitivity	13.6%
24	Vasculitis, Leukocytoclastic, Cutaneous	13.3%
25	Hereditary Angioedema Type III	12.7%
26	Hereditary Angioedema Types I and II	12.7%
27	Transfusion Reaction	12.2%
28	Hypotensive Transfusion Reaction	12.2%
29	Asthma, Occupational	12%
30	Farmer's Lung	11.6%
31	Aspergillosis, Allergic Bronchopulmonary	11.6%
32	Angioedemas, Hereditary	11.6%
33	Hay fever	11.4%
34	Rhinitis, Allergic, Perennial	11.4%
35	Antiphospholipid Syndrome	10.3%
36	Mastocytosis	10.1%
37	Drug Eruptions	10%
38	Dermatitis, Allergic Contact	9.8%
39	Mastocytosis, Systemic	9.7%
40	Glomerulonephritis, Membranoproliferative	8.5%
41	Acute Generalized Exanthematous Pustulosis	7.3%
42	Lupus Erythematosus, Systemic	7%
43	Lymphoproliferative Disorders	7%
44	Overlap syndrome	7%
45	Autoimmune Lymphoproliferative Syndrome	6.8%
46	Addison Disease	6.8%
47	Paraproteinemias	6.8%
48	Pemphigus	6.8%
49	Autoimmune thyroiditis	6.8%
50	Primary Adrenal Insufficiency	6.8%
51	Lymphopenia	6.7%
52	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	6.7%
53	Autoimmune hepatitis	6.7%
54	Erythema Nodosum	5.9%
55	Dermatitis, Photoallergic	5.8%
56	Thrombocytopenic purpura	5.6%
57	Primary amyloidosis	5.3%
58	Monoclonal Gammopathy of Undetermined Significance	5.3%
59	Hypergammaglobulinemia	5.2%
60	Latent Autoimmune Diabetes in Adults	5.1%
61	Agammaglobulinemia	5.1%
62	Dermatitis Herpetiformis	5.1%
63	HIV Infections	5%
64	Transfusion-Related Acute Lung Injury	5%
65	Autoimmune thrombocytopenia	5%
66	Immune thrombocytopenic purpura	5%
67	Schnitzler Syndrome	4.9%
68	Plasmacytoma	4.4%
69	Tumor Lysis Syndrome	4.4%
70	HTLV-I Infections	4.4%
71	Job Syndrome	4.4%
72	Toxic Epidermal Necrolysis	4.2%
73	Stevens-Johnson Syndrome	4.2%
74	Rheumatoid Arthritis	4.1%
75	Juvenile arthritis	4.1%
76	Graves Disease	4.1%
77	Anti-Glomerular Basement Membrane Disease	4%
78	Multiple Myeloma	3.8%
79	Lymphoma	3.4%
80	Myasthenia Gravis	3.4%
81	Uveomeningoencephalitic Syndrome	3.4%
82	Chronic granulomatous disease	3.3%
83	Heavy Chain Disease	3.3%
84	Sezary Syndrome	3.3%
85	Granulomatosis with polyangiitis	3.3%
86	HIV Seropositivity	3.3%
87	Kernicterus	2.9%
88	Myasthenia Gravis, Autoimmune, Experimental	2.8%
89	Stiff-Person Syndrome	2.7%
90	Polyradiculoneuropathy	2.7%
91	Polyradiculoneuritis	2.7%
92	Acquired Immunodeficiency Syndrome	2.7%
93	AIDS related complex	2.7%
94	Infectious Mononucleosis	2.6%
95	Cryoglobulinemia	2.6%
96	Felty Syndrome	2.6%
97	POEMS Syndrome	2.6%
98	Lupus Nephritis	2.6%
99	Ataxia Telangiectasia	2.5%
100	Hydrops Fetalis	2.5%
101	Multiple Sclerosis	2.5%
102	Hodgkin Disease	2.5%
103	Leukemia, Plasma Cell	2.5%
104	Lymphoma, Non-Hodgkin	2.5%
105	Leukemia, T-Cell	2.4%
106	Leukemia, B-Cell	2.4%
107	AIDS-Related Opportunistic Infections	2.3%
108	Vasculitis, Central Nervous System	2.2%
109	HIV Wasting Syndrome	2.2%
110	Rheumatoid Vasculitis	2.2%
111	AIDS Dementia Complex	2.2%
112	AIDS-Associated Nephropathy	2.2%
113	Multiple Sclerosis, Chronic Progressive	2%
114	Multiple Sclerosis, Relapsing-Remitting	2%
115	Lymphoma, Follicular	2%
116	T-Cell Lymphoma	2%
117	Mantle cell lymphoma	2%
118	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	2%
119	Leukemia, Large Granular Lymphocytic	2%
120	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	2%
121	Neuromyelitis Optica	2%
122	Leukoencephalitis, Acute Hemorrhagic	2%
123	Composite Lymphoma	2%
124	Encephalomyelitis, Acute Disseminated	2%
125	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2%
126	Neuritis, Autoimmune, Experimental	2%
127	Lymphangioleiomyomatosis	1.9%
128	Lambert-Eaton Myasthenic Syndrome	1.9%
129	Lupus Vasculitis, Central Nervous System	1.9%
130	Waldenstrom Macroglobulinemia	1.9%
131	Wiskott-Aldrich Syndrome	1.9%
132	Sicca Syndrome	1.9%
133	Sjogren's Syndrome	1.9%
134	HIV-Associated Lipodystrophy Syndrome	1.9%
135	Lymphoma, T-Cell, Cutaneous	1.8%
136	Lymphoma, AIDS-Related	1.8%
137	Enteropathy-Associated T-Cell Lymphoma	1.8%
138	Primary Effusion Lymphoma	1.8%
139	Mycosis Fungoides	1.7%
140	Lymphomatoid Papulosis	1.7%
141	Plasmablastic lymphoma	1.7%
142	Guillain-Barre Syndrome	1.6%
143	Lymphomatoid Granulomatosis	1.5%
144	Giant Cell Arteritis	1.2%
145	Temporal Arteritis	1.2%
146	Burkitt Lymphoma	1.2%
147	Myelitis, Transverse	1.1%
148	Miller Fisher Syndrome	0.9%

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