MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pleuropericarditis

(UMLS:C1167732)

Definition:: Inflammation of both the PERICARDIUM and the PLEURA.
UMLS ID:: C1167732
MeSH ID:: D010493

Classification:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.720

Synonym(s)

Pleuropericarditis

pleuropericarditis

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Leflunomide	FAERS: 5	US FAERS
2	Methotrexate	FAERS: 4	US FAERS
3	Sulfasalazine	FAERS: 4	US FAERS
4	Imatinib Mesylate	FAERS: 3 Canada Vigilance: 1	Canada Vigilance US FAERS
5	Mesalamine	FAERS: 3	OFFSIDES SIDER US FAERS
6	Ibuprofen	FAERS: 2	US FAERS
7	NuvaRing	FAERS: 2	US FAERS
8	PCI 32765	FAERS: 2	US FAERS
9	Simvastatin	FAERS: 2	US FAERS
10	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1	US FAERS
11	Atorvastatin	FAERS: 1	US FAERS
12	Docetaxel	FAERS: 1	US FAERS
13	Fingolimod Hydrochloride	FAERS: 1	US FAERS
14	Naltrexone	FAERS: 1	US FAERS
15	Paliperidone Palmitate	FAERS: 1	US FAERS
16	Valproic Acid	FAERS: 1	US FAERS
17	ambrisentan	FAERS: 1	US FAERS
18	balsalazide	FAERS: 1	US FAERS
19	bosutinib	FAERS: 1	US FAERS
20	rofecoxib	FAERS: 1	US FAERS
21	tofacitinib	FAERS: 1	US FAERS
22	Beclomethasone		OFFSIDES
23	Beclomethasone		OFFSIDES
24	Bleomycin		SIDER
25	Cabergoline		OFFSIDES
26	Cyclophosphamide	Canada Vigilance: 2	Canada Vigilance
27	Folic Acid		OFFSIDES
28	Oxaprozin		OFFSIDES
29	Ribavirin		OFFSIDES
30	Tretinoin		OFFSIDES
31	chlorhexidine gluconate		OFFSIDES
32	mecobalamin		OFFSIDES
33	norgestimate, ethinyl estradiol drug combination		OFFSIDES
34	olmesartan		OFFSIDES
35	trandolapril		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Cardiac Tamponade	42.9%
2	Endocarditis	42.9%
3	Cardiac Arrest	42.9%
4	Heart failure	42.9%
5	Pericardial effusion	42.9%
6	Pneumopericardium	42.9%
7	Cor pulmonale	42.9%
8	Ventricular Outflow Obstruction	42.9%
9	Ventricular Dysfunction	42.9%
10	Cardiomyopathies	42.9%
11	Aortic Valve Stenosis	40.9%
12	Cardiomyopathy, Dilated	40.9%
13	Pulmonary Valve Stenosis	40.9%
14	Myocardial Ischemia	38.1%
15	Hypertrophic Cardiomyopathy	35.2%
16	Hypertrophic obstructive cardiomyopathy	35.2%
17	Supravalvular aortic stenosis	33.3%
18	Lown-Ganong-Levine Syndrome	33.3%
19	Aortic Valve Insufficiency	31%
20	Restrictive cardiomyopathy	31%
21	Endocardial Fibroelastosis	31%
22	Heart Rupture, Post-Infarction	31%
23	Mitral Valve Insufficiency	31%
24	Mitral Valve Stenosis	31%
25	Myocarditis	31%
26	Pulmonary Valve Insufficiency	31%
27	Tricuspid Valve Insufficiency	31%
28	Tricuspid Valve Stenosis	31%
29	Ventricular Dysfunction, Left	31%
30	Right Ventricular Dysfunction	31%
31	Endomyocardial Fibrosis	31%
32	Carditis	31%
33	Heart Failure, Systolic	31%
34	Heart Failure, Diastolic	31%
35	Heart Block	30.5%
36	Tachycardia	30.5%
37	Tachyarrhythmia	30.5%
38	Cardiac Output, High	28.6%
39	Myocardial Stunning	28.6%
40	Low Cardiac Output Syndrome	28.6%
41	Tricuspid Atresia	28.2%
42	Arrhythmogenic Right Ventricular Dysplasia	28.2%
43	Cardiomegaly	27.9%
44	Postpericardiotomy Syndrome	27.9%
45	Cardiac Hypertrophy	27.9%
46	Rheumatic Heart Disease	27.4%
47	Coronary heart disease	27.3%
48	Myocardial Infarction	27.3%
49	Acute Coronary Syndrome	27.3%
50	Myocardial Reperfusion Injury	26.8%
51	Aortic Valve Prolapse	25.4%
52	Tricuspid Valve Prolapse	25.4%
53	Takotsubo Cardiomyopathy	25.4%
54	Adams-Stokes Syndrome	24.8%
55	Atrioventricular Block	24.8%
56	Bundle-Branch Block	24.8%
57	Atrial Premature Complexes	24.8%
58	Sinoatrial Block	24.8%
59	Tachycardia, Paroxysmal	24.8%
60	Supraventricular tachycardia	24.8%
61	Tachycardia, Ventricular	24.8%
62	Wolff-Parkinson-White Syndrome	24.8%
63	Tachycardia, Reciprocating	24.8%
64	Sick Sinus Syndrome	24.6%
65	Long QT Syndrome	24.2%
66	Vascular Diseases	23.1%
67	Coronary Occlusion	22.2%
68	Microvascular Angina	22.2%
69	Coronary Stenosis	22.2%
70	ST segment elevation myocardial infarction	22.2%
71	Tachycardia, Atrioventricular Nodal Reentry	22%
72	Tachycardia, Ectopic Atrial	22%
73	Tachycardia, Ectopic Junctional	22%
74	Sinus Tachycardia	22%
75	Torsades de Pointes	22%
76	Accelerated Idioventricular Rhythm	22%
77	Coronary Aneurysm	21.7%
78	Kounis Syndrome	20.7%
79	Coronary Thrombosis	20.7%
80	Coronary Artery Disease	20.7%
81	Sinus Arrhythmia	20.5%
82	Atrial Fibrillation	20.5%
83	Atrial Flutter	20.5%
84	Edema, Cardiac	20.5%
85	Ventricular Fibrillation	20.5%
86	Ventricular Flutter	20.5%
87	Parasystole	20.5%
88	Paroxysmal atrial fibrillation	20.5%
89	Bradycardia	20.5%
90	Diabetic Cardiomyopathies	20.5%
91	Cardiomyopathy, Alcoholic	20.2%
92	Sudden Cardiac Death	20.2%
93	Left Ventricular Hypertrophy	20.2%
94	Right Ventricular Hypertrophy	20.2%
95	Aortic coarctation	20.2%
96	Cor Triatriatum	20.2%
97	Coronary Vessel Anomalies	20.2%
98	Patent ductus arteriosus	20.2%
99	Ebstein Anomaly	20.2%
100	Heart Septal Defects	20.2%
101	Tetralogy of Fallot	20.2%
102	Transposition of Great Vessels	20.2%
103	Hypoplastic Left Heart Syndrome	20.2%
104	Chagas Cardiomyopathy	20.1%
105	Angina Pectoris	20.1%
106	Coronary Restenosis	19.8%
107	Romano-Ward Syndrome	19.7%
108	Bacterial Endocarditis	18.1%
109	Shock, Cardiogenic	16.7%
110	Sinus Arrest, Cardiac	16.7%
111	Aortopulmonary Septal Defect	16.5%
112	Double Outlet Right Ventricle	16.5%
113	Endocardial Cushion Defects	16.5%
114	Myocardial bridging	16.5%
115	Aorticopulmonary Septal Defect	16.5%
116	Angina, Unstable	16.4%
117	Dextrocardia	16.1%
118	Carcinoid Heart Disease	15.8%
119	Dyspnea, Paroxysmal	15.1%
120	Pregnancy Complications, Cardiovascular	15%
121	Cardiovascular Abnormalities	15%
122	Truncus Arteriosus, Persistent	14.7%
123	Angina Pectoris, Variant	14.6%
124	Aneurysm	14.3%
125	Angiomatosis	14.3%
126	Aortic Diseases	14.3%
127	Arterial Occlusive Diseases	14.3%
128	Hyperemia	14.3%
129	Hypotension	14.3%
130	Superior Vena Cava Syndrome	14.3%
131	Telangiectasis	14.3%
132	Vasculitis	14.3%
133	Venous Insufficiency	14.3%
134	Peripheral Vascular Diseases	14.3%
135	Embolism and Thrombosis	14.3%
136	Angiodysplasia	14.3%
137	Capillary Leak Syndrome	14.3%
138	Prehypertension	14.3%
139	Aortic Aneurysm	13.6%
140	Aortitis	13.6%
141	Leriche Syndrome	13.6%
142	Periphlebitis	13.6%
143	Phlebitis	13.6%
144	Thromboangiitis Obliterans	13.6%
145	Postphlebitic Syndrome	12.4%
146	Thrombophlebitis	11.9%
147	Subacute Bacterial Endocarditis	11.6%
148	Noonan Syndrome	11.5%
149	Blue Toe Syndrome	11.4%
150	Embolism, Amniotic Fluid	11.1%
151	Aortic Aneurysm, Abdominal	11.1%
152	Aortic Aneurysm, Thoracic	11.1%
153	Retinal Vein Occlusion	10.8%
154	Arteriovenous fistula	10.4%
155	Aneurysm, Dissecting	10.3%
156	Arteriosclerosis	10.3%
157	Arteritis	10.3%
158	Embolism	10.3%
159	Erythromelalgia	10.3%
160	Fibromuscular Dysplasia	10.3%
161	Malignant Hypertension	10.3%
162	Raynaud Disease	10.3%
163	Thromboembolism	10.3%
164	Thrombosis	10.3%
165	Essential Hypertension	10.3%
166	Aneurysm, Ruptured	10.3%
167	Iliac Aneurysm	10.3%
168	Pulmonary artery stenosis	10.3%
169	White Coat Hypertension	10.3%
170	Systemic Vasculitis	10.3%
171	Embolus	10.3%
172	Marfan Syndrome	10.2%
173	Malignant Atrophic Papulosis	10.2%
174	Shwartzman Phenomenon	10.1%
175	May-Thurner Syndrome	10.1%
176	Aortic Rupture	10.1%
177	Vascular System Injuries	10%
178	Compartment syndromes	9.5%
179	Hepatic Veno-Occlusive Disease	9.5%
180	Peliosis Hepatis	9.5%
181	Varicocele	9.5%
182	Carotid Artery Thrombosis	9.5%
183	Cerebrovascular Disorders	9.3%
184	Diabetic Angiopathies	9.3%
185	Reperfusion Injury	9.3%
186	Splenic Infarction	9.3%
187	Cerebrovascular Insufficiency	9.3%
188	Vascular Neoplasms	9.3%
189	Spinal Cord Vascular Diseases	9.3%
190	Vasoplegia	9.3%
191	Hemorrhoids	9.2%
192	Thoracic Outlet Syndrome	9.2%
193	Intracranial Embolism and Thrombosis	9.2%
194	Carotid Stenosis	9.1%
195	Intracranial Aneurysm	9.1%
196	Williams Syndrome	9%
197	Arteriosclerosis Obliterans	8.5%
198	Atherosclerosis	8.5%
199	Air Embolism	8.5%
200	Endarteritis	8.5%
201	Venous Thrombosis	8.5%
202	Deep Vein Thrombosis	8.5%
203	Venous Thromboembolism	8.5%
204	Moyamoya Disease	8.4%
205	Polyarteritis Nodosa	8.3%
206	Takayasu Arteritis	8.3%
207	Intracranial Arteriosclerosis	8.2%
208	Cerebral Atherosclerosis	8.2%
209	Cerebral Arteriosclerosis	8.2%
210	Cerebral Thrombosis	7.8%
211	Intracranial Embolism	7.8%
212	Intracranial Thrombosis	7.8%
213	Hand-Arm Vibration Syndrome	7.3%
214	Sinus Thrombosis, Intracranial	7.1%
215	Optic Neuropathy, Ischemic	7%
216	Anterior Ischemic Optic Neuropathy	7%
217	Mesenteric vascular insufficiency	7%
218	Retinal Artery Occlusion	7%
219	Retinal Vasculitis	7%
220	Hypertensive Retinopathy	7%
221	Scimitar Syndrome	6.9%
222	Anterior Compartment Syndrome	6.8%
223	Vasculitis, Leukocytoclastic, Cutaneous	6.8%
224	Gastric Antral Vascular Ectasia	6.8%
225	Abdominal Compartment Syndrome	6.8%
226	Cavernous Sinus Thrombosis	6.8%
227	Sagittal Sinus Thrombosis	6.8%
228	Angioedema	6.8%
229	Vasculitis, Central Nervous System	6.8%
230	Colitis, Ischemic	6.8%
231	Carotid Artery Diseases	6.7%
232	Brain Ischemia	6.7%
233	Ectopia Cordis	6.7%
234	Hypotension, Orthostatic	6.7%
235	Cerebrovascular accident	6.7%
236	Varicose Ulcer	6.7%
237	Vasospasm, Intracranial	6.7%
238	Spinal Cord Ischemia	6.7%
239	Intracranial Arterial Diseases	6.7%
240	Primary Graft Dysfunction	6.7%
241	Single umbilical artery	6.7%
242	Post-Exercise Hypotension	6.7%
243	Brain Infarction	6.5%
244	Lemierre Syndrome	6.3%
245	Giant Cell Arteritis	6.2%
246	Temporal Arteritis	6.2%
247	Infarction, Middle Cerebral Artery	5.9%
248	Infarction, Anterior Cerebral Artery	5.9%
249	Infarction, Posterior Cerebral Artery	5.9%
250	Cerebral Infarction	5.8%
251	Brain Stem Infarctions	5.8%
252	Intermittent Claudication	5.7%
253	Pulmonary Embolism	5.7%
254	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5.7%
255	Subarachnoid Hemorrhage, Traumatic	5.7%
256	Carotid Artery, Internal, Dissection	5.7%
257	No-Reflow Phenomenon	5.6%
258	Turner Syndrome	5.6%
259	Cerebral Arterial Diseases	5.5%
260	Vertebrobasilar Insufficiency	5.5%
261	Anterior Spinal Artery Syndrome	5.5%
262	Basilar Artery Stenosis	5.5%
263	Vertebral Artery Stenosis	5.5%
264	Intracranial Hemorrhage, Hypertensive	5.5%
265	Transient Cerebral Ischemia	5.5%
266	Vertebral Artery Dissection	5.5%
267	Lateral Medullary Syndrome	5.5%
268	Kearns-Sayre syndrome	5.3%
269	Mesenteric Vascular Occlusion	5.2%
270	Mucocutaneous Lymph Node Syndrome	5.2%
271	Kartagener Syndrome	5.2%
272	CREST Syndrome	5.2%
273	Hepatic Vein Thrombosis	5.1%
274	Budd-Chiari Syndrome	5.1%
275	Diabetic Retinopathy	5.1%
276	Sturge-Weber Syndrome	5.1%
277	Livedo Reticularis	5.1%
278	Renal hypertension	5%
279	Renal Artery Obstruction	5%
280	Renal Artery Stenosis	5%
281	Pulmonary Infarction	5%
282	Hemangioma, Cavernous	5%
283	Basal Ganglia Cerebrovascular Disease	5%
284	Vascular Headaches	5%
285	Scurvy	5%
286	Subclavian Steal Syndrome	4.9%
287	Carotid Artery Injuries	4.7%
288	Basal Ganglia Hemorrhage	4.4%
289	Hypertension, Renovascular	4.1%
290	Subarachnoid Hemorrhage	4.1%
291	Hypoxia-Ischemia, Brain	4.1%
292	Cerebral Hemorrhage	4.1%
293	Dural Arteriovenous Fistula	4.1%
294	Hereditary Angioedema Type III	4.1%
295	Hereditary Angioedema Types I and II	4.1%
296	Ischemic contracture	4.1%
297	Angioedemas, Hereditary	4%
298	Putaminal Hemorrhage	4%
299	Cryoglobulinemia	4%
300	Leukomalacia, Periventricular	4%
301	Diabetic Foot	4%
302	Granulomatosis with polyangiitis	3.8%
303	Cerebral Amyloid Angiopathy	3.7%
304	Dementia, Vascular	3.7%
305	Pituitary Apoplexy	3.3%
306	Shy-Drager Syndrome	3.3%
307	Purpura, Hyperglobulinemic	3.3%
308	Behcet Syndrome	2.9%
309	Waldenstrom Macroglobulinemia	2.9%
310	Multiple Myeloma	2.9%
311	Rheumatoid Vasculitis	2.8%
312	Lupus Vasculitis, Central Nervous System	2.7%
313	Ataxia Telangiectasia	2.5%
314	Pseudoxanthoma Elasticum	2.5%
315	Hematoma, Subdural	2.1%
316	Hematoma, Epidural, Cranial	2.1%
317	Hematoma, Subdural, Intracranial	2%
318	Hematoma, Subdural, Chronic	2%
319	Hematoma, Subdural, Acute	2%
320	Brain Hemorrhage, Traumatic	1.8%
321	MELAS Syndrome	1.6%
322	Fabry Disease	1.2%

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