MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypotensive Transfusion Reaction

(UMLS:C3267086)

UMLS ID:: C3267086
MeSH ID:: D065227

Classification 1:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.378.962

Classification 2:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.920

Synonym(s)

Hypotensive Transfusion Reaction

Hypotensive transfusion reaction

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Lisinopril	FAERS: 28	US FAERS
2	Enalapril	FAERS: 1	US FAERS
3	benazepril	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Disseminated Intravascular Coagulation	38%
2	Protein S Deficiency	38%
3	Thrombocythemia, Essential	37%
4	Anemia	30%
5	Blood Coagulation Disorders	30%
6	Blood Platelet Disorders	30%
7	Bone Marrow Diseases	30%
8	Hemorrhagic Disorders	30%
9	Leukocyte Disorders	30%
10	Methemoglobinemia	30%
11	Pancytopenia	30%
12	Polycythemia	30%
13	Sulfhemoglobinemia	30%
14	Thrombophilia	30%
15	Erythrocytosis	30%
16	Thrombasthenia	29.5%
17	Antithrombin III Deficiency	29.5%
18	Protein C Deficiency	29.5%
19	Thrombocytosis	29.2%
20	Monoclonal Gammopathy of Undetermined Significance	28.7%
21	Afibrinogenemia	27.6%
22	Factor VII Deficiency	27.6%
23	Factor X Deficiency	27.6%
24	Factor XII Deficiency	27.6%
25	Hemophilia A	27.6%
26	Activated Protein C Resistance	27.6%
27	Factor II deficiency	27.6%
28	Factor VIII Deficiency	27.6%
29	Factor V deficiency	27.6%
30	Factor XI Deficiency	27.6%
31	Hypoprothrombinemias	27.6%
32	Paraproteinemias	27.3%
33	Hemoglobinuria, Paroxysmal	26.3%
34	Leukemoid Reaction	26.3%
35	Autoimmune thrombocytopenia	25.8%
36	Immune thrombocytopenic purpura	25.8%
37	Agammaglobulinemia	25.7%
38	Polycythemia Vera	25.6%
39	Bone Marrow Neoplasms	25.4%
40	Vitamin K Deficiency	25.1%
41	Lymphopenia	24.3%
42	Wiskott-Aldrich Syndrome	24.1%
43	Anemia, Diamond-Blackfan	23.9%
44	Cryoglobulinemia	23%
45	Pregnancy Complications, Hematologic	22.2%
46	Hematologic Neoplasms	22.2%
47	Thrombocytopenic purpura	22.2%
48	Job Syndrome	22.1%
49	Anemia, Hemolytic	22%
50	Anemia, Macrocytic	22%
51	Eosinophilia	22%
52	Hypoproteinemia	22%
53	Leukopenia	22%
54	Thrombocytopenia	22%
55	Leukostasis	22%
56	MYELODYSPLASTIC SYNDROME	22%
57	Hypergammaglobulinemia	21.7%
58	Heavy Chain Disease	21.7%
59	Multiple Myeloma	21.4%
60	Purpura, Thrombotic Thrombocytopenic	21.2%
61	Autoimmune Diseases	21.1%
62	Hypersensitivity	21.1%
63	Immunologic Deficiency Syndromes	21.1%
64	Immunoproliferative Disorders	21.1%
65	Immune reconstitution syndrome	21.1%
66	Immune Reconstitution Inflammatory Syndrome	21.1%
67	Waldenstrom Macroglobulinemia	19.7%
68	Infectious Mononucleosis	19.7%
69	Lymphoproliferative Disorders	18.5%
70	Anemia, Sickle Cell	18.2%
71	Thalassemia	18.2%
72	Primary Myelofibrosis	18.1%
73	Agranulocytosis	18.1%
74	Anemia, Megaloblastic	18.1%
75	Lymphocytosis	18.1%
76	Myelofibrosis	18.1%
77	Myeloid Metaplasia	18.1%
78	Hypoalbuminemia	18.1%
79	Hypereosinophilic syndrome	18.1%
80	bone marrow fibrosis	18.1%
81	Thrombotic Microangiopathies	18.1%
82	Chronic granulomatous disease	17.5%
83	Autoimmune Lymphoproliferative Syndrome	16.7%
84	Hydrops Fetalis	16.5%
85	Anemia, Neonatal	16.4%
86	Leukocytosis	16.4%
87	Pelger-Huet Anomaly	16.4%
88	Pleocytosis	16.4%
89	Neutropenia	16.2%
90	Hemolytic-Uremic Syndrome	16.1%
91	Lymphatic Diseases	15.8%
92	Sickle Cell Trait	15.7%
93	Fanconi Anemia	15.4%
94	Febrile Neutropenia	15.2%
95	Immune Complex Diseases	15%
96	Antiphospholipid Syndrome	15%
97	Latex allergy	15%
98	Atypical Hemolytic Uremic Syndrome	14.7%
99	Purpura, Hyperglobulinemic	14.6%
100	POEMS Syndrome	14.4%
101	Tumor Lysis Syndrome	14.3%
102	Sezary Syndrome	13.6%
103	Leukemia, Myelomonocytic, Chronic	13.2%
104	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	13.2%
105	Kernicterus	13%
106	Ecchymosis	12.7%
107	Petechiae	12.7%
108	Purpura	12.7%
109	anaphylaxis	12.2%
110	Food Allergy	12.2%
111	Anaphylactic shock	12.2%
112	Pulmonary Eosinophilia	12.1%
113	Eosinophilic Pneumonia	12.1%
114	Acute Chest Syndrome	11.9%
115	Leukemia, Myeloid, Chronic-Phase	11.7%
116	Anemia, Pernicious	11.7%
117	Primary amyloidosis	11.6%
118	Environmental Illness	11.5%
119	Glomerulonephritis, Membranoproliferative	11.5%
120	Lymphoma	11.4%
121	Lupus Erythematosus, Systemic	11.1%
122	Overlap syndrome	11.1%
123	Addison Disease	10.9%
124	Pemphigus	10.9%
125	Autoimmune thyroiditis	10.9%
126	Primary Adrenal Insufficiency	10.9%
127	Serum Sickness	10.9%
128	Milk Allergy	10.8%
129	Schnitzler Syndrome	10.8%
130	Wheat Hypersensitivity	10.8%
131	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	10.8%
132	Autoimmune hepatitis	10.8%
133	Eosinophilia-Myalgia Syndrome	10.6%
134	Shwartzman Phenomenon	10.5%
135	Hemangioma, Cavernous	10.4%
136	Scurvy	10.4%
137	Purpura Fulminans	10.3%
138	Adenitis	10%
139	Histiocytosis	10%
140	Lymphadenitis	10%
141	Lymphangitis	10%
142	Lymphedema	10%
143	Splenic Diseases	10%
144	Thymus Hyperplasia	10%
145	Pseudolymphoma	10%
146	Lymphadenopathy	10%
147	Waterhouse-Friderichsen Syndrome	10%
148	Asthma, Aspirin-Induced	9.9%
149	Eosinophilic Granuloma	9.9%
150	Hodgkin Disease	9.7%
151	Lymphoma, Non-Hodgkin	9.7%
152	Leukemia, T-Cell	9.7%
153	Leukemia, B-Cell	9.7%
154	Respiratory Hypersensitivity	9.4%
155	Sick Building Syndrome	9.1%
156	Multiple Chemical Sensitivity	9.1%
157	Plasmacytoma	8.9%
158	Urticaria	8.9%
159	Vasculitis, Leukocytoclastic, Cutaneous	8.9%
160	Lymphoma, Follicular	8.9%
161	T-Cell Lymphoma	8.9%
162	Mantle cell lymphoma	8.9%
163	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	8.9%
164	Leukemia, Large Granular Lymphocytic	8.9%
165	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	8.9%
166	HTLV-I Infections	8.8%
167	Latent Autoimmune Diabetes in Adults	8.6%
168	Dermatitis Herpetiformis	8.6%
169	Kounis Syndrome	8.6%
170	HIV Infections	8.5%
171	Lymphoma, T-Cell, Cutaneous	8.5%
172	Lymphoma, AIDS-Related	8.5%
173	Enteropathy-Associated T-Cell Lymphoma	8.5%
174	Primary Effusion Lymphoma	8.5%
175	Lymphangiectasis, Intestinal	8.5%
176	Mycosis Fungoides	8.3%
177	Lymphomatoid Papulosis	8.3%
178	Plasmablastic lymphoma	8.3%
179	Composite Lymphoma	8%
180	Lymphangioleiomyomatosis	8%
181	Mastocytosis, Systemic	7.9%
182	Myasthenia Gravis, Autoimmune, Experimental	7.6%
183	Lymphocele	7.4%
184	Lymphatic Abnormalities	7.4%
185	Elephantiasis	7.3%
186	Hypersplenism	7.3%
187	Sarcoidosis	7.3%
188	Elephantiasis Nostras Verrucosa	7.3%
189	Thymus Neoplasms	7.3%
190	Rheumatoid Arthritis	7.1%
191	Lymphomatoid Granulomatosis	7.1%
192	Myasthenia Gravis	7.1%
193	Uveomeningoencephalitic Syndrome	7.1%
194	Juvenile arthritis	7.1%
195	Mastocytosis	7.1%
196	Graves Disease	7.1%
197	Drug Eruptions	7%
198	Granulomatosis with polyangiitis	7%
199	Dermatitis, Allergic Contact	6.9%
200	Anti-Glomerular Basement Membrane Disease	6.9%
201	HIV Seropositivity	6.9%
202	Angioedema	6.3%
203	Multiple Sclerosis	6.3%
204	Leukemia, Plasma Cell	6.2%
205	Acute Generalized Exanthematous Pustulosis	6.2%
206	Lymphohistiocytosis, Hemophagocytic	6%
207	Erdheim-Chester Disease	6%
208	Burkitt Lymphoma	6%
209	Stiff-Person Syndrome	6%
210	Asthma, Exercise-Induced	5.9%
211	Status Asthmaticus	5.9%
212	Polyradiculoneuropathy	5.9%
213	Polyradiculoneuritis	5.9%
214	Neuromyelitis Optica	5.9%
215	Multiple Sclerosis, Chronic Progressive	5.8%
216	Multiple Sclerosis, Relapsing-Remitting	5.8%
217	Leukoencephalitis, Acute Hemorrhagic	5.8%
218	Acquired Immunodeficiency Syndrome	5.8%
219	AIDS related complex	5.8%
220	Felty Syndrome	5.7%
221	Pseudoxanthoma Elasticum	5.7%
222	Mucocutaneous Lymph Node Syndrome	5.7%
223	Lupus Nephritis	5.7%
224	Hereditary Angioedema Type III	5.6%
225	Hereditary Angioedema Types I and II	5.6%
226	Granuloma	5.5%
227	Histiocytic Disorders, Malignant	5.5%
228	Splenic Infarction	5.5%
229	Splenic Neoplasms	5.5%
230	Histiocytosis, Langerhans-Cell	5.4%
231	Asthma	5.3%
232	Encephalomyelitis, Acute Disseminated	5.2%
233	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	5.2%
234	Erythema Nodosum	5.1%
235	Neuritis, Autoimmune, Experimental	5.1%
236	Dermatitis, Photoallergic	5.1%
237	Asthma, Occupational	5.1%
238	AIDS-Related Opportunistic Infections	5%
239	Vasculitis, Central Nervous System	5%
240	Dermatitis, Atopic	5%
241	Farmer's Lung	4.9%
242	Angioedemas, Hereditary	4.9%
243	HIV Wasting Syndrome	4.9%
244	Rheumatoid Vasculitis	4.9%
245	AIDS Dementia Complex	4.9%
246	AIDS-Associated Nephropathy	4.9%
247	Lupus Vasculitis, Central Nervous System	4.9%
248	Hay fever	4.8%
249	Rhinitis, Allergic, Perennial	4.8%
250	Ataxia Telangiectasia	4.6%
251	Aspergillosis, Allergic Bronchopulmonary	4.4%
252	Malignant histiocytosis	4.4%
253	Sarcoidosis, Pulmonary	4.4%
254	Histiocytic sarcoma	4.4%
255	Guillain-Barre Syndrome	4.4%
256	Splenic Rupture	4.3%
257	Lambert-Eaton Myasthenic Syndrome	4.3%
258	Sicca Syndrome	4.3%
259	Sjogren's Syndrome	4.3%
260	HIV-Associated Lipodystrophy Syndrome	4.2%
261	Thymoma	4.2%
262	Toxic Epidermal Necrolysis	3.8%
263	Stevens-Johnson Syndrome	3.8%
264	Splenosis	3.5%
265	Giant Cell Arteritis	3.4%
266	Temporal Arteritis	3.4%
267	Myelitis, Transverse	3%
268	Miller Fisher Syndrome	2.9%
269	Niemann-Pick Disease, Type C	1.2%

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