MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Immune Complex Diseases

(UMLS:C0020951)

Definition:: Group of diseases mediated by the deposition of large soluble complexes of antigen and antibody with resultant damage to tissue. Besides SERUM SICKNESS and the ARTHUS REACTION, evidence supports a pathogenic role for immune complexes in many other IMMUNE SYSTEM DISEASES including GLOMERULONEPHRITIS, systemic lupus erythematosus (LUPUS ERYTHEMATOSUS, SYSTEMIC) and POLYARTERITIS NODOSA.
UMLS ID:: C0020951
MeSH ID:: D007105

Classification:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.520

Synonym(s)

Immune Complex Diseases

Immune complex disease

Immune complex diseases

Immune complex formation syndrome

hypersensitivity iii type

immune complex disease

immune complex diseases

type iii hypersensitivity

Associated Drug(s)

	Name	Reference(s)	Data Source
1	15(S)-15-methylprostaglandin E1	159314	CTD
2	Ampicillin	6236237	CTD
3	Cefoxitin	10204595	CTD
4	Dinoprostone	159314	CTD
5	Mercuric Chloride	1825860 6214344	CTD
6	Penicillamine	122655 159020	CTD
7	Propylthiouracil	17472842	CTD
8	Prostaglandin D2	159314	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Latex allergy	42.9%
2	anaphylaxis	31%
3	Food Allergy	31%
4	Anaphylactic shock	31%
5	Environmental Illness	30%
6	Milk Allergy	25.4%
7	Wheat Hypersensitivity	25.4%
8	Autoimmune Diseases	23.1%
9	Immunologic Deficiency Syndromes	23.1%
10	Immunoproliferative Disorders	23.1%
11	Immune reconstitution syndrome	23.1%
12	Immune Reconstitution Inflammatory Syndrome	23.1%
13	Respiratory Hypersensitivity	22%
14	Sick Building Syndrome	20.9%
15	Multiple Chemical Sensitivity	20.9%
16	Kounis Syndrome	20.7%
17	Urticaria	20.5%
18	Asthma, Aspirin-Induced	20.2%
19	Drug Eruptions	15.3%
20	Dermatitis, Allergic Contact	15%
21	Transfusion Reaction	15%
22	Hypotensive Transfusion Reaction	15%
23	Antiphospholipid Syndrome	14.3%
24	Angioedema	12.7%
25	Acute Generalized Exanthematous Pustulosis	12.4%
26	Asthma, Exercise-Induced	11.3%
27	Status Asthmaticus	11.3%
28	Glomerulonephritis, Membranoproliferative	10.4%
29	Hereditary Angioedema Type III	10.4%
30	Hereditary Angioedema Types I and II	10.4%
31	Asthma	10.3%
32	Dermatitis, Atopic	10.1%
33	Erythema Nodosum	9.9%
34	Serum Sickness	9.9%
35	Dermatitis, Photoallergic	9.9%
36	Autoimmune Lymphoproliferative Syndrome	9.7%
37	Lupus Erythematosus, Systemic	9.5%
38	Lymphoproliferative Disorders	9.5%
39	Overlap syndrome	9.5%
40	Asthma, Occupational	9.4%
41	Addison Disease	9.3%
42	Paraproteinemias	9.3%
43	Pemphigus	9.3%
44	Autoimmune thyroiditis	9.3%
45	Primary Adrenal Insufficiency	9.3%
46	Lymphopenia	9.2%
47	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	9.2%
48	Autoimmune hepatitis	9.2%
49	Farmer's Lung	9.1%
50	Angioedemas, Hereditary	9.1%
51	Hay fever	8.9%
52	Rhinitis, Allergic, Perennial	8.9%
53	Schnitzler Syndrome	8.5%
54	Aspergillosis, Allergic Bronchopulmonary	8.4%
55	Primary amyloidosis	8.1%
56	Monoclonal Gammopathy of Undetermined Significance	8%
57	Toxic Epidermal Necrolysis	7%
58	Stevens-Johnson Syndrome	7%
59	Hypergammaglobulinemia	7%
60	Latent Autoimmune Diabetes in Adults	7%
61	Agammaglobulinemia	6.9%
62	Dermatitis Herpetiformis	6.9%
63	HIV Infections	6.8%
64	Transfusion-Related Acute Lung Injury	6.8%
65	Plasmacytoma	6.8%
66	Tumor Lysis Syndrome	6.8%
67	Thrombocytopenic purpura	6.8%
68	HTLV-I Infections	6.7%
69	Job Syndrome	6.7%
70	Autoimmune thrombocytopenia	6.7%
71	Immune thrombocytopenic purpura	6.7%
72	Multiple Myeloma	5.7%
73	Rheumatoid Arthritis	5.6%
74	Juvenile arthritis	5.6%
75	Sezary Syndrome	5.5%
76	Graves Disease	5.5%
77	Anti-Glomerular Basement Membrane Disease	5.4%
78	Lymphoma	5.2%
79	Myasthenia Gravis	5.2%
80	Uveomeningoencephalitic Syndrome	5.2%
81	Chronic granulomatous disease	5%
82	Heavy Chain Disease	5%
83	Granulomatosis with polyangiitis	5%
84	HIV Seropositivity	5%
85	Myasthenia Gravis, Autoimmune, Experimental	4.7%
86	Multiple Sclerosis	4.2%
87	Hodgkin Disease	4.2%
88	Leukemia, Plasma Cell	4.2%
89	Lymphoma, Non-Hodgkin	4.2%
90	Stiff-Person Syndrome	4.2%
91	Polyradiculoneuropathy	4.1%
92	Polyradiculoneuritis	4.1%
93	Leukemia, T-Cell	4.1%
94	Leukemia, B-Cell	4.1%
95	Acquired Immunodeficiency Syndrome	4%
96	AIDS related complex	4%
97	Infectious Mononucleosis	4%
98	Cryoglobulinemia	4%
99	Felty Syndrome	4%
100	POEMS Syndrome	4%
101	Lupus Nephritis	4%
102	Kernicterus	3.9%
103	Multiple Sclerosis, Chronic Progressive	3.7%
104	Multiple Sclerosis, Relapsing-Remitting	3.7%
105	Lymphoma, Follicular	3.7%
106	T-Cell Lymphoma	3.7%
107	Mantle cell lymphoma	3.7%
108	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
109	Leukemia, Large Granular Lymphocytic	3.7%
110	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.7%
111	Neuromyelitis Optica	3.5%
112	Lymphoma, T-Cell, Cutaneous	3.5%
113	Lymphoma, AIDS-Related	3.5%
114	Enteropathy-Associated T-Cell Lymphoma	3.5%
115	Primary Effusion Lymphoma	3.5%
116	Leukoencephalitis, Acute Hemorrhagic	3.4%
117	AIDS-Related Opportunistic Infections	3.4%
118	Ataxia Telangiectasia	3.4%
119	Vasculitis, Central Nervous System	3.4%
120	Mycosis Fungoides	3.3%
121	Lymphomatoid Papulosis	3.3%
122	Plasmablastic lymphoma	3.3%
123	Hydrops Fetalis	3.3%
124	Composite Lymphoma	3.3%
125	HIV Wasting Syndrome	3.3%
126	Encephalomyelitis, Acute Disseminated	3.3%
127	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	3.3%
128	Rheumatoid Vasculitis	3.3%
129	Neuritis, Autoimmune, Experimental	3.3%
130	AIDS Dementia Complex	3.3%
131	AIDS-Associated Nephropathy	3.3%
132	Lymphangioleiomyomatosis	3.3%
133	Lupus Vasculitis, Central Nervous System	3%
134	Lambert-Eaton Myasthenic Syndrome	2.9%
135	Waldenstrom Macroglobulinemia	2.9%
136	Wiskott-Aldrich Syndrome	2.9%
137	Sicca Syndrome	2.8%
138	Sjogren's Syndrome	2.8%
139	Lymphomatoid Granulomatosis	2.8%
140	HIV-Associated Lipodystrophy Syndrome	2.8%
141	Guillain-Barre Syndrome	2.8%
142	Burkitt Lymphoma	2.3%
143	Giant Cell Arteritis	2.1%
144	Temporal Arteritis	2.1%
145	Myelitis, Transverse	1.8%
146	Miller Fisher Syndrome	1.6%

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