MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Waldenstrom Macroglobulinemia

(UMLS:C0024419)

Definition:: A lymphoproliferative disorder characterized by pleomorphic B-LYMPHOCYTES including PLASMA CELLS, with increased levels of monoclonal serum IMMUNOGLOBULIN M. There is lymphoplasmacytic cells infiltration into bone marrow and often other tissues, also known as lymphoplasmacytic lymphoma. Clinical features include ANEMIA; HEMORRHAGES; and hyperviscosity.
UMLS ID:: C0024419
MeSH ID:: D008258

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.595.925

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.454.960

Classification 3:

Name:

Hemic and Lymphatic Diseases
MeSH Tree Number(s):: C15.378.147.780.925|C15.378.463.515.960|C15.604.515.925

Classification 4:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.683.780.925

Synonym(s)

Waldenstrom Macroglobulinemia

Lymphoplasmacytic Lymphoma/Waldenstr枚m Macroglobulinemia

Lymphoplasmacytic Lymphoma/Waldenstr枚m's Macroglobulinemia

Macroglobulinaemia

Macroglobulinemia

Primary macroglobulinaemia

Primary macroglobulinemia

WALDENSTROMS MACROGLOBULINEMIA

Waldenstrom macroglobulinemia

10.

Waldenstrom's Macroglobulinemia

11.

Waldenstrom's macroglobulinaemia

12.

Waldenstrom's macroglobulinemia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Bortezomib	18347188	CTD
2	Chlorambucil	16432856	CTD
3	Cladribine	7948311 10721776 16432856	CTD
4	Dexamethasone	18347188	CTD
5	Diatrizoate Meglumine	3922320	CTD
6	Doxorubicin	2791187	CTD
7	Prednisone	16432856	CTD
8	Resveratrol	18347188	CTD
9	Thalidomide	17408102	CTD
10	fludarabine	10721776 18347188	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Multiple Myeloma	47.8%
2	Cryoglobulinemia	44.1%
3	Heavy Chain Disease	37%
4	Monoclonal Gammopathy of Undetermined Significance	33.6%
5	Shwartzman Phenomenon	28.9%
6	Disseminated Intravascular Coagulation	28.7%
7	Protein S Deficiency	28.7%
8	Hemangioma, Cavernous	27.7%
9	Agammaglobulinemia	27.4%
10	Thrombocythemia, Essential	27.1%
11	Purpura, Hyperglobulinemic	24.4%
12	Scurvy	24.4%
13	Lymphoma	23.7%
14	Thrombasthenia	23.4%
15	Antithrombin III Deficiency	23.4%
16	Protein C Deficiency	23.4%
17	Sezary Syndrome	22.6%
18	Infectious Mononucleosis	22.4%
19	Primary amyloidosis	22.4%
20	POEMS Syndrome	22%
21	Afibrinogenemia	21.1%
22	Factor VII Deficiency	21.1%
23	Factor X Deficiency	21.1%
24	Factor XII Deficiency	21.1%
25	Hemophilia A	21.1%
26	Factor II deficiency	21.1%
27	Factor VIII Deficiency	21.1%
28	Factor V deficiency	21.1%
29	Factor XI Deficiency	21.1%
30	Hypoprothrombinemias	21.1%
31	Vitamin K Deficiency	20.5%
32	Transfusion Reaction	19.7%
33	Hypotensive Transfusion Reaction	19.7%
34	Hypergammaglobulinemia	19.4%
35	Composite Lymphoma	19.1%
36	Tumor Lysis Syndrome	19%
37	Wiskott-Aldrich Syndrome	17.7%
38	Bone Marrow Neoplasms	17.6%
39	Hematologic Neoplasms	17.6%
40	Autoimmune Lymphoproliferative Syndrome	17.4%
41	Anemia	17.1%
42	Blood Coagulation Disorders	17.1%
43	Blood Platelet Disorders	17.1%
44	Bone Marrow Diseases	17.1%
45	Leukocyte Disorders	17.1%
46	Methemoglobinemia	17.1%
47	Pancytopenia	17.1%
48	Polycythemia	17.1%
49	Sulfhemoglobinemia	17.1%
50	Thrombophilia	17.1%
51	Erythrocytosis	17.1%
52	Pseudoxanthoma Elasticum	17.1%
53	Activated Protein C Resistance	17.1%
54	Autoimmune thrombocytopenia	17.1%
55	Immune thrombocytopenic purpura	17.1%
56	Lymphangioleiomyomatosis	17%
57	Hodgkin Disease	16.8%
58	Lymphoma, Non-Hodgkin	16.8%
59	Plasmacytoma	16.5%
60	Hypoproteinemia	16%
61	Sarcoidosis	16%
62	Polycythemia Vera	15.7%
63	Leukemia, T-Cell	15.6%
64	Leukemia, B-Cell	15.6%
65	Leukemia, Plasma Cell	15.3%
66	Thrombocytosis	15.2%
67	Pregnancy Complications, Hematologic	15.1%
68	Histiocytic Disorders, Malignant	15%
69	Splenic Infarction	15%
70	Mucocutaneous Lymph Node Syndrome	14.8%
71	Lymphocele	14.3%
72	Granuloma	14.2%
73	Lymphoma, Follicular	13.4%
74	T-Cell Lymphoma	13.4%
75	Mantle cell lymphoma	13.4%
76	Adenitis	13.3%
77	Histiocytosis	13.3%
78	Lymphadenitis	13.3%
79	Lymphangitis	13.3%
80	Lymphedema	13.3%
81	Splenic Diseases	13.3%
82	Thymus Hyperplasia	13.3%
83	Pseudolymphoma	13.3%
84	Lymphadenopathy	13.3%
85	Thymus Neoplasms	13.3%
86	Lymphangiectasis, Intestinal	13.2%
87	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	12.8%
88	Leukemia, Large Granular Lymphocytic	12.8%
89	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	12.8%
90	Purpura, Thrombotic Thrombocytopenic	12.8%
91	Lymphomatoid Granulomatosis	12.6%
92	Anemia, Diamond-Blackfan	12.4%
93	Hemoglobinuria, Paroxysmal	12.3%
94	Leukemoid Reaction	12.3%
95	Thymoma	12.1%
96	Lymphoproliferative Disorders	11.8%
97	Lymphatic Abnormalities	11.8%
98	Lymphoma, T-Cell, Cutaneous	11.7%
99	Lymphoma, AIDS-Related	11.7%
100	Enteropathy-Associated T-Cell Lymphoma	11.7%
101	Primary Effusion Lymphoma	11.7%
102	Medulloblastoma	11.3%
103	Thrombocytopenic purpura	11%
104	Anemia, Sickle Cell	11%
105	Thalassemia	11%
106	Neoplasms, Neuroepithelial	10.9%
107	Gliomatosis cerebri	10.9%
108	Mycosis Fungoides	10.9%
109	Lymphomatoid Papulosis	10.9%
110	Plasmablastic lymphoma	10.9%
111	Hypoalbuminemia	10.8%
112	Waterhouse-Friderichsen Syndrome	10.6%
113	Anemia, Hemolytic	10.4%
114	Anemia, Macrocytic	10.4%
115	Eosinophilia	10.4%
116	Leukopenia	10.4%
117	Thrombocytopenia	10.4%
118	Leukostasis	10.4%
119	MYELODYSPLASTIC SYNDROME	10.4%
120	Transfusion-Related Acute Lung Injury	10.3%
121	Malignant histiocytosis	10.3%
122	Sarcoidosis, Pulmonary	10.3%
123	Histiocytic sarcoma	10.3%
124	Myocardial Ischemia	10.1%
125	Hydrops Fetalis	10%
126	Hemorrhagic Disorders	10%
127	Splenic Neoplasms	10%
128	Aortic Aneurysm	9.9%
129	Aortitis	9.9%
130	Leriche Syndrome	9.9%
131	Periphlebitis	9.9%
132	Phlebitis	9.9%
133	Thromboangiitis Obliterans	9.9%
134	Neuroectodermal Tumors	9.9%
135	Schnitzler Syndrome	9.9%
136	Leukemia, Myelomonocytic, Chronic	9.8%
137	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	9.8%
138	melanoma	9.8%
139	Burkitt Lymphoma	9.6%
140	Myocardial Reperfusion Injury	9.6%
141	Retinal Vein Occlusion	9.5%
142	Thrombophlebitis	9.3%
143	Anemia, Neonatal	9.2%
144	Leukocytosis	9.2%
145	Pelger-Huet Anomaly	9.2%
146	Pleocytosis	9.2%
147	Vascular Neoplasms	9.2%
148	Aortic Rupture	8.9%
149	Malignant Atrophic Papulosis	8.8%
150	Coronary Aneurysm	8.8%
151	Lymphatic Diseases	8.7%
152	Lymphopenia	8.7%
153	Meningioma	8.7%
154	Adenoma, Acidophil	8.7%
155	Ganglioneuroma	8.7%
156	Glioma	8.7%
157	Malignant Glioma	8.7%
158	Carcinosarcoma	8.6%
159	Hemangiosarcoma	8.6%
160	lymphangiosarcoma	8.6%
161	Postphlebitic Syndrome	8.6%
162	Hemolytic-Uremic Syndrome	8.6%
163	Aneurysm	8.6%
164	Angiomatosis	8.6%
165	Aortic Diseases	8.6%
166	Arterial Occlusive Diseases	8.6%
167	Hyperemia	8.6%
168	Hypotension	8.6%
169	leukemia	8.6%
170	Neoplasms, Germ Cell and Embryonal	8.6%
171	Neoplasms, Glandular and Epithelial	8.6%
172	Superior Vena Cava Syndrome	8.6%
173	Telangiectasis	8.6%
174	Vasculitis	8.6%
175	Venous Insufficiency	8.6%
176	Peripheral Vascular Diseases	8.6%
177	Embolism and Thrombosis	8.6%
178	Angiodysplasia	8.6%
179	Capillary Leak Syndrome	8.6%
180	Germ Cell Cancer	8.6%
181	Prehypertension	8.6%
182	Melanoma, Experimental	8.5%
183	Elephantiasis	8.5%
184	Hypersplenism	8.5%
185	Elephantiasis Nostras Verrucosa	8.5%
186	Vasculitis, Central Nervous System	8.5%
187	Moyamoya Disease	8.4%
188	Eosinophilic Granuloma	8.4%
189	Carotid Artery Thrombosis	8.3%
190	Carcinoma 256, Walker	8.3%
191	Carcinoid Heart Disease	8.2%
192	Arteriovenous fistula	8.2%
193	Kounis Syndrome	8.1%
194	Carcinoid Tumor	8.1%
195	Neurilemmoma	8.1%
196	Hutchinson's Melanotic Freckle	8.1%
197	Melanoma, Amelanotic	8.1%
198	Ecchymosis	8.1%
199	Petechiae	8.1%
200	Purpura	8.1%
201	Sickle Cell Trait	8.1%
202	Job Syndrome	7.8%
203	Kernicterus	7.8%
204	Leukemia, Myeloid, Chronic-Phase	7.8%
205	Sturge-Weber Syndrome	7.7%
206	Angioedema	7.7%
207	Vascular System Injuries	7.7%
208	Blue Toe Syndrome	7.7%
209	Intracranial Embolism and Thrombosis	7.7%
210	Carotid Stenosis	7.7%
211	Intracranial Aneurysm	7.7%
212	Coronary Thrombosis	7.6%
213	Coronary Artery Disease	7.6%
214	Astrocytoma	7.6%
215	Ependymoma	7.6%
216	oligodendroglioma	7.6%
217	Ganglioglioma	7.6%
218	gliosarcoma	7.6%
219	Anaplastic astrocytoma	7.6%
220	Anaplastic Oligodendroglioma	7.6%
221	Compartment syndromes	7.6%
222	Hepatic Veno-Occlusive Disease	7.6%
223	Peliosis Hepatis	7.6%
224	Varicocele	7.6%
225	Giant Cell Arteritis	7.5%
226	Temporal Arteritis	7.5%
227	Fanconi Anemia	7.5%
228	Cerebrovascular Disorders	7.5%
229	Diabetic Angiopathies	7.5%
230	Reperfusion Injury	7.5%
231	Cerebrovascular Insufficiency	7.5%
232	Spinal Cord Vascular Diseases	7.5%
233	Vasoplegia	7.5%
234	Hemorrhoids	7.5%
235	Thoracic Outlet Syndrome	7.5%
236	Histiocytosis, Langerhans-Cell	7.4%
237	Basal cell carcinoma	7.4%
238	Carcinoma, Papillary	7.4%
239	Squamous cell carcinoma	7.4%
240	Chondrosarcoma	7.4%
241	Craniopharyngioma	7.4%
242	Cystadenoma	7.4%
243	leiomyosarcoma	7.4%
244	liposarcoma	7.4%
245	Mesothelioma	7.4%
246	synovial sarcoma	7.4%
247	Aortic Aneurysm, Abdominal	7.4%
248	Aortic Aneurysm, Thoracic	7.4%
249	Neuroectodermal Tumor, Melanotic	7.4%
250	Angiomyolipoma	7.4%
251	Clear Cell Sarcoma of Soft Tissue	7.4%
252	Alveolar Soft Part Sarcoma	7.4%
253	Neuroendocrine Tumors	7.4%
254	Sarcoma, Myeloid	7.4%
255	Carcinoma, Basal Cell	7.4%
256	Malignant Carcinoid Syndrome	7.3%
257	Primary Myelofibrosis	7%
258	Agranulocytosis	7%
259	Anemia, Megaloblastic	7%
260	Lymphocytosis	7%
261	Myelofibrosis	7%
262	Myeloid Metaplasia	7%
263	Hypereosinophilic syndrome	7%
264	bone marrow fibrosis	7%
265	Thrombotic Microangiopathies	7%
266	Glioblastoma	7%
267	Neuroblastoma	7%
268	Glioblastoma Multiforme	7%
269	Chronic granulomatous disease	7%
270	Atypical Hemolytic Uremic Syndrome	6.9%
271	Retinoblastoma	6.8%
272	Acute Chest Syndrome	6.8%
273	Hand-Arm Vibration Syndrome	6.8%
274	Ganglioneuroblastoma	6.8%
275	Cystadenocarcinoma	6.7%
276	Fibrosarcoma	6.7%
277	Osteosarcoma	6.7%
278	Mucoepidermoid Carcinoma	6.7%
279	Splenic Rupture	6.7%
280	Optic Neuropathy, Ischemic	6.7%
281	Anterior Ischemic Optic Neuropathy	6.7%
282	Mesenteric vascular insufficiency	6.7%
283	Choriocarcinoma	6.7%
284	Carcinoma, Lobular	6.7%
285	Trophoblastic Neoplasms	6.7%
286	Leukemia, Experimental	6.6%
287	Coronary heart disease	6.6%
288	Myocardial Infarction	6.6%
289	Vasculitis, Leukocytoclastic, Cutaneous	6.6%
290	Acute Coronary Syndrome	6.6%
291	Colitis, Ischemic	6.6%
292	Waldenstrom Macroglobulinemia	6.6%
293	Polyarteritis Nodosa	6.6%
294	Takayasu Arteritis	6.6%
295	Intracranial Arteriosclerosis	6.5%
296	Cerebral Atherosclerosis	6.5%
297	Cerebral Arteriosclerosis	6.5%
298	Adenofibroma	6.4%
299	Fibroadenoma	6.4%
300	Malignant Fibrous Histiocytoma	6.4%
301	Neurofibrosarcoma	6.4%
302	Endometrial Stromal Sarcoma	6.3%
303	Carcinoma, Ehrlich Tumor	6.2%
304	Dermoid Cyst	6.2%
305	Carcinoma, Lewis Lung	6.2%
306	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	6.2%
307	Scimitar Syndrome	6.2%
308	Bowen's Disease	6.1%
309	Paraganglioma	6.1%
310	Rhabdomyosarcoma	6.1%
311	Giant Cell Tumor of Bone	6.1%
312	Lymphohistiocytosis, Hemophagocytic	6.1%
313	Erdheim-Chester Disease	6.1%
314	Leukemia, Radiation-Induced	6%
315	Cerebral Thrombosis	6%
316	Intracranial Embolism	6%
317	Intracranial Thrombosis	6%
318	Subarachnoid Hemorrhage, Traumatic	6%
319	Carotid Artery, Internal, Dissection	6%
320	Lemierre Syndrome	6%
321	Brain Infarction	5.9%
322	May-Thurner Syndrome	5.9%
323	Angina Pectoris	5.9%
324	Dermatofibrosarcoma	5.8%
325	Dermatofibrosarcoma Protuberans	5.8%
326	CREST Syndrome	5.7%
327	Adenoma	5.7%
328	Ameloblastoma	5.7%
329	Aneurysm, Dissecting	5.7%
330	Angiokeratoma	5.7%
331	Arteriosclerosis	5.7%
332	Arteritis	5.7%
333	Carcinoma	5.7%
334	Chordoma	5.7%
335	Embolism	5.7%
336	Erythromelalgia	5.7%
337	Fibromuscular Dysplasia	5.7%
338	Hemangioma	5.7%
339	hemangiopericytoma	5.7%
340	Malignant Hypertension	5.7%
341	Lymphangioma	5.7%
342	Mesenchymoma	5.7%
343	Nevus	5.7%
344	Raynaud Disease	5.7%
345	Teratoma	5.7%
346	Thromboembolism	5.7%
347	Thrombosis	5.7%
348	Essential Hypertension	5.7%
349	Aneurysm, Ruptured	5.7%
350	Iliac Aneurysm	5.7%
351	Hepatoblastoma	5.7%
352	Mixed Tumor, Mullerian	5.7%
353	Germinoma	5.7%
354	Teratocarcinoma	5.7%
355	Angiofibroma	5.7%
356	Pulmonary artery stenosis	5.7%
357	White Coat Hypertension	5.7%
358	Systemic Vasculitis	5.7%
359	Sarcoma	5.7%
360	Epithelioma	5.7%
361	Embolus	5.7%
362	Infarction, Middle Cerebral Artery	5.6%
363	Infarction, Anterior Cerebral Artery	5.6%
364	Infarction, Posterior Cerebral Artery	5.6%
365	Acoustic Neuroma	5.6%
366	Embolism, Amniotic Fluid	5.5%
367	Eosinophilia-Myalgia Syndrome	5.5%
368	Sarcoma, Experimental	5.5%
369	Pheochromocytoma	5.5%
370	Alveolar rhabdomyosarcoma	5.5%
371	Purpura Fulminans	5.5%
372	Paraproteinemias	5.4%
373	Neutropenia	5.4%
374	Vertebral Artery Dissection	5.4%
375	Leukemia L1210	5.3%
376	Leukemia P388	5.3%
377	Acanthoma	5.3%
378	Optic Nerve Glioma	5.2%
379	Basal Cell Nevus Syndrome	5.1%
380	Sinus Thrombosis, Intracranial	5.1%
381	Carcinoma, Pancreatic Ductal	5.1%
382	Retinal Artery Occlusion	5%
383	Retinal Vasculitis	5%
384	Hypertensive Retinopathy	5%
385	Anterior Compartment Syndrome	5%
386	Gastric Antral Vascular Ectasia	5%
387	Abdominal Compartment Syndrome	5%
388	Carotid Artery Diseases	4.9%
389	Brain Ischemia	4.9%
390	Hypotension, Orthostatic	4.9%
391	Cerebrovascular accident	4.9%
392	Varicose Ulcer	4.9%
393	Vasospasm, Intracranial	4.9%
394	Spinal Cord Ischemia	4.9%
395	Intracranial Arterial Diseases	4.9%
396	Primary Graft Dysfunction	4.9%
397	Post-Exercise Hypotension	4.9%
398	Coronary Occlusion	4.9%
399	Microvascular Angina	4.9%
400	Coronary Stenosis	4.9%
401	ST segment elevation myocardial infarction	4.9%
402	Multiple Endocrine Neoplasia	4.9%
403	Carotid Artery Injuries	4.9%
404	Cerebral Infarction	4.9%
405	Brain Stem Infarctions	4.9%
406	Autoimmune Diseases	4.9%
407	Hamartoma	4.9%
408	Heart Diseases	4.9%
409	Hypersensitivity	4.9%
410	Immunologic Deficiency Syndromes	4.9%
411	Neoplasms, Hormone-Dependent	4.9%
412	Neoplasms, Multiple Primary	4.9%
413	Paraneoplastic Syndromes	4.9%
414	Precancerous Conditions	4.9%
415	Neoplasms, Second Primary	4.9%
416	Immune reconstitution syndrome	4.9%
417	Immune Reconstitution Inflammatory Syndrome	4.9%
418	Nephroblastoma	4.8%
419	Mastocytosis	4.8%
420	Lupus Vasculitis, Central Nervous System	4.8%
421	Angioedemas, Hereditary	4.8%
422	Pulmonary Eosinophilia	4.8%
423	Splenosis	4.8%
424	Eosinophilic Pneumonia	4.8%
425	Cavernous Sinus Thrombosis	4.7%
426	Sagittal Sinus Thrombosis	4.7%
427	Sarcoma 180	4.7%
428	Anemia, Pernicious	4.7%
429	Ataxia Telangiectasia	4.6%
430	Vipoma	4.6%
431	Febrile Neutropenia	4.6%
432	Basal Ganglia Hemorrhage	4.5%
433	Mesenteric Vascular Occlusion	4.4%
434	Diabetic Retinopathy	4.4%
435	Livedo Reticularis	4.4%
436	Renal hypertension	4.4%
437	Renal Artery Obstruction	4.4%
438	Renal Artery Stenosis	4.4%
439	Shock, Cardiogenic	4.4%
440	Basal Ganglia Cerebrovascular Disease	4.4%
441	Vascular Headaches	4.4%
442	Lateral Medullary Syndrome	4.4%
443	Angina, Unstable	4.4%
444	Mastocytosis, Systemic	4.3%
445	Cyst	4.3%
446	Neoplastic Processes	4.3%
447	Neoplastic Syndromes, Hereditary	4.3%
448	Pregnancy Complications, Cardiovascular	4.3%
449	Pregnancy Complications, Neoplastic	4.3%
450	Cardiovascular Abnormalities	4.3%
451	Neoplasms, Experimental	4.2%
452	Adenocarcinoma	4.2%
453	Arteriosclerosis Obliterans	4.2%
454	Atherosclerosis	4.2%
455	Carcinoma in Situ	4.2%
456	Carcinoma, Transitional Cell	4.2%
457	Phyllodes Tumor	4.2%
458	Dysgerminoma	4.2%
459	Air Embolism	4.2%
460	Endarteritis	4.2%
461	Hemangioendothelioma	4.2%
462	Lipoma	4.2%
463	Myoma	4.2%
464	Myxoma	4.2%
465	Neuroma	4.2%
466	Papilloma	4.2%
467	Pseudomyxoma Peritonei	4.2%
468	Seminoma	4.2%
469	Venous Thrombosis	4.2%
470	Deep Vein Thrombosis	4.2%
471	Papillomatosis	4.2%
472	Angiolipoma	4.2%
473	Myelolipoma	4.2%
474	Neoplasms, Bone Tissue	4.2%
475	Neoplasms, Fibrous Tissue	4.2%
476	Smooth Muscle Tumor	4.2%
477	Adenomatosis, Pulmonary	4.2%
478	Adenomatous Polyps	4.2%
479	Carcinoma, Large Cell	4.2%
480	Carcinoma, Small Cell	4.2%
481	Desmoplastic Small Round Cell Tumor	4.2%
482	Chondroma	4.2%
483	Enchondroma	4.2%
484	Venous Thromboembolism	4.2%
485	Granulomatosis with polyangiitis	4.2%
486	Coronary Restenosis	4.1%
487	Hereditary Angioedema Type III	4.1%
488	Hereditary Angioedema Types I and II	4.1%
489	Tuberous Sclerosis	4%
490	Ischemic contracture	4%
491	Tricuspid Atresia	4%
492	Arrhythmogenic Right Ventricular Dysplasia	4%
493	Leukomalacia, Periventricular	3.9%
494	Hepatocellular Adenoma	3.9%
495	Mesoblastic Nephroma	3.9%
496	Diabetic Foot	3.9%
497	Rheumatoid Vasculitis	3.9%
498	Putaminal Hemorrhage	3.8%
499	Hydatidiform Mole	3.8%
500	Neoplasms, Radiation-Induced	3.8%
501	Dementia, Vascular	3.8%
502	Intermittent Claudication	3.7%
503	Pulmonary Embolism	3.7%
504	Paraneoplastic Encephalomyelitis	3.7%
505	Glomerulonephritis, Membranoproliferative	3.7%
506	No-Reflow Phenomenon	3.7%
507	Mammary Neoplasms, Experimental	3.7%
508	Cerebral Arterial Diseases	3.7%
509	Vertebrobasilar Insufficiency	3.7%
510	Anterior Spinal Artery Syndrome	3.7%
511	Basilar Artery Stenosis	3.7%
512	Vertebral Artery Stenosis	3.7%
513	Intracranial Hemorrhage, Hypertensive	3.7%
514	Transient Cerebral Ischemia	3.7%
515	Angina Pectoris, Variant	3.6%
516	Shy-Drager Syndrome	3.6%
517	Prolactinoma	3.6%
518	Growth Hormone-Secreting Pituitary Adenoma	3.6%
519	Adenoid Cystic Carcinoma	3.5%
520	fibroma	3.5%
521	Fibromatosis	3.5%
522	Osteoblastoma	3.5%
523	Osteoma	3.5%
524	Rhabdomyoma	3.5%
525	Chondromatosis	3.5%
526	Adenocarcinoma, Clear Cell	3.5%
527	Cholangiocarcinoma	3.5%
528	Cervical Intraepithelial Neoplasia	3.5%
529	Hemangioblastoma	3.5%
530	Lymphoma, Extranodal NK-T-Cell	3.5%
531	Adenomatous Polyposis Coli	3.4%
532	insulinoma	3.4%
533	Bacterial Endocarditis	3.4%
534	Behcet Syndrome	3.3%
535	Aortic Valve Stenosis	3.3%
536	Cardiomyopathy, Dilated	3.3%
537	Pulmonary Valve Stenosis	3.3%
538	Gastrointestinal Stromal Tumors	3.3%
539	Multiple Endocrine Neoplasia Type 1	3.3%
540	Hypertension, Renovascular	3.3%
541	neurofibroma	3.3%
542	Subarachnoid Hemorrhage	3.3%
543	Hypoxia-Ischemia, Brain	3.3%
544	Cerebral Hemorrhage	3.3%
545	granulosa cell tumor	3.3%
546	Carcinoma, Ovarian Epithelial	3.3%
547	Gastrinoma	3.2%
548	Glucagonoma	3.2%
549	Fibromatosis, Aggressive	3.2%
550	Fibromatosis, Abdominal	3.2%
551	Klatskin Tumor	3.2%
552	Hepatic Vein Thrombosis	3.1%
553	Budd-Chiari Syndrome	3.1%
554	Mastocytoma	3.1%
555	Pulmonary Infarction	3.1%
556	Subclavian Steal Syndrome	3.1%
557	Lambert-Eaton Myasthenic Syndrome	3%
558	Leydig Cell Tumor	3%
559	Pituitary Apoplexy	3%
560	Adrenocortical carcinoma	3%
561	Heart Block	2.9%
562	Tachycardia	2.9%
563	Tachyarrhythmia	2.9%
564	Aortic coarctation	2.9%
565	Cor Triatriatum	2.9%
566	Coronary Vessel Anomalies	2.9%
567	Patent ductus arteriosus	2.9%
568	Ebstein Anomaly	2.9%
569	Heart Septal Defects	2.9%
570	Tetralogy of Fallot	2.9%
571	Transposition of Great Vessels	2.9%
572	Hypoplastic Left Heart Syndrome	2.9%
573	Abdominal Neoplasms	2.9%
574	Cardiac Tamponade	2.9%
575	Endocarditis	2.9%
576	Erythroplasia	2.9%
577	Follicular cyst	2.9%
578	Head and Neck Neoplasms	2.9%
579	Cardiac Arrest	2.9%
580	Heart failure	2.9%
581	Immune Complex Diseases	2.9%
582	Mucocele	2.9%
583	Pericardial effusion	2.9%
584	Pericarditis	2.9%
585	Pilonidal Cyst	2.9%
586	Pneumopericardium	2.9%
587	Cor pulmonale	2.9%
588	Soft Tissue Neoplasms	2.9%
589	Thoracic Neoplasms	2.9%
590	Thyroglossal Cyst	2.9%
591	Ventricular Outflow Obstruction	2.9%
592	Antiphospholipid Syndrome	2.9%
593	Synovial Cyst	2.9%
594	Ventricular Dysfunction	2.9%
595	Latex allergy	2.9%
596	Cardiomyopathies	2.9%
597	Pleuropericarditis	2.9%
598	Aberrant Crypt Foci	2.9%
599	Nasopharyngeal carcinoma	2.8%
600	Denys-Drash Syndrome	2.7%
601	Cerebral Amyloid Angiopathy	2.7%
602	Liver Neoplasms, Experimental	2.7%
603	Renal Cell Carcinoma	2.7%
604	Papillary Renal Cell Carcinoma	2.7%
605	Parathyroid Neoplasms	2.7%
606	Peritoneal Neoplasms	2.7%
607	Thyroid Neoplasm	2.7%
608	Thyroid carcinoma	2.7%
609	Sick Sinus Syndrome	2.7%
610	Hypertrophic Cardiomyopathy	2.7%
611	Hypertrophic obstructive cardiomyopathy	2.7%
612	Dextrocardia	2.6%
613	Long QT Syndrome	2.6%
614	Carcinoma, Endometrioid	2.6%
615	Digestive System Neoplasms	2.6%
616	Endocrine Gland Neoplasms	2.6%
617	Eye Neoplasms	2.6%
618	Nervous System Neoplasms	2.6%
619	Environmental Illness	2.6%
620	Bone neoplasms	2.5%
621	Leukoplakia	2.5%
622	Lupus Erythematosus, Systemic	2.5%
623	Pancreatic Cyst	2.5%
624	Skin Neoplasms	2.5%
625	Cardiac Output, High	2.5%
626	Myocardial Stunning	2.5%
627	Overlap syndrome	2.5%
628	Low Cardiac Output Syndrome	2.5%
629	Addison Disease	2.5%
630	Barrett Esophagus	2.5%
631	Breast Cyst	2.5%
632	Cardiomegaly	2.5%
633	Actinic keratosis	2.5%
634	Mediastinal Cyst	2.5%
635	Neoplasm Invasiveness	2.5%
636	Neoplasm Metastasis	2.5%
637	Neoplasm Recurrence, Local	2.5%
638	Parovarian Cyst	2.5%
639	Pemphigus	2.5%
640	Pericardial Cyst	2.5%
641	Postpericardiotomy Syndrome	2.5%
642	Thymic Cyst	2.5%
643	Carcinogenesis	2.5%
644	Autoimmune thyroiditis	2.5%
645	Myxoid cyst	2.5%
646	Cardiac Hypertrophy	2.5%
647	Primary Adrenal Insufficiency	2.5%
648	Metastasis	2.5%
649	Autoimmune hepatitis	2.5%
650	Rheumatic Heart Disease	2.5%
651	Dupuytren Contracture	2.5%
652	Supravalvular aortic stenosis	2.5%
653	Lown-Ganong-Levine Syndrome	2.5%
654	Urticaria Pigmentosa	2.5%
655	Pancreatic Neoplasm	2.5%
656	Asthma, Aspirin-Induced	2.4%
657	Myelitis, Transverse	2.3%
658	Tracheal Neoplasms	2.3%
659	Leukoplakia, Oral	2.3%
660	Paraneoplastic Cerebellar Degeneration	2.3%
661	Serum Sickness	2.3%
662	Latent Autoimmune Diabetes in Adults	2.2%
663	Dermatitis Herpetiformis	2.2%
664	HIV Infections	2.2%
665	Corpus Luteum Cyst	2.2%
666	Noonan Syndrome	2.2%
667	Ovarian Cysts	2.2%
668	Adams-Stokes Syndrome	2.2%
669	Atrioventricular Block	2.2%
670	Bundle-Branch Block	2.2%
671	Atrial Premature Complexes	2.2%
672	Sinoatrial Block	2.2%
673	Tachycardia, Paroxysmal	2.2%
674	Supraventricular tachycardia	2.2%
675	Tachycardia, Ventricular	2.2%
676	Wolff-Parkinson-White Syndrome	2.2%
677	Tachycardia, Reciprocating	2.2%
678	Aortopulmonary Septal Defect	2.2%
679	Double Outlet Right Ventricle	2.2%
680	Endocardial Cushion Defects	2.2%
681	Myocardial bridging	2.2%
682	Aorticopulmonary Septal Defect	2.2%
683	Esophageal Neoplasms	2.1%
684	Niemann-Pick Disease, Type C	2.1%
685	Subacute Bacterial Endocarditis	2.1%
686	Limbic Encephalitis	2.1%
687	Marfan Syndrome	2.1%
688	Hematoma, Subdural	2%
689	Hematoma, Epidural, Cranial	2%
690	Rheumatoid Arthritis	2%
691	Choledochal Cyst	2%
692	Juvenile arthritis	2%
693	Graves Disease	2%
694	Peutz-Jeghers Syndrome	2%
695	Anti-Glomerular Basement Membrane Disease	2%
696	Thyroid Nodule	2%
697	Romano-Ward Syndrome	2%
698	MELAS Syndrome	1.9%
699	Testicular Neoplasms	1.9%
700	anaphylaxis	1.9%
701	Aortic Valve Insufficiency	1.9%
702	Restrictive cardiomyopathy	1.9%
703	Endocardial Fibroelastosis	1.9%
704	Food Allergy	1.9%
705	Heart Rupture, Post-Infarction	1.9%
706	Mitral Valve Insufficiency	1.9%
707	Mitral Valve Stenosis	1.9%
708	Myocarditis	1.9%
709	Pericarditis, Constrictive	1.9%
710	Pulmonary Valve Insufficiency	1.9%
711	Retroperitoneal Neoplasms	1.9%
712	Tricuspid Valve Insufficiency	1.9%
713	Tricuspid Valve Stenosis	1.9%
714	Ventricular Dysfunction, Left	1.9%
715	Right Ventricular Dysfunction	1.9%
716	Endomyocardial Fibrosis	1.9%
717	Carditis	1.9%
718	Heart Failure, Systolic	1.9%
719	Heart Failure, Diastolic	1.9%
720	Anaphylactic shock	1.9%
721	Brain Hemorrhage, Traumatic	1.9%
722	Hematoma, Subdural, Intracranial	1.8%
723	Hematoma, Subdural, Chronic	1.8%
724	Hematoma, Subdural, Acute	1.8%
725	Tachycardia, Atrioventricular Nodal Reentry	1.8%
726	Tachycardia, Ectopic Atrial	1.8%
727	Tachycardia, Ectopic Junctional	1.8%
728	Sinus Tachycardia	1.8%
729	Torsades de Pointes	1.8%
730	Accelerated Idioventricular Rhythm	1.8%
731	Truncus Arteriosus, Persistent	1.8%
732	Opsoclonus-Myoclonus Syndrome	1.8%
733	Respiratory Hypersensitivity	1.7%
734	Mouth Neoplasms	1.7%
735	Sick Building Syndrome	1.7%
736	Central Nervous System Neoplasms	1.7%
737	Multiple Chemical Sensitivity	1.7%
738	Sinus Arrhythmia	1.7%
739	Atrial Fibrillation	1.7%
740	Atrial Flutter	1.7%
741	Edema, Cardiac	1.7%
742	Genital Neoplasms, Female	1.7%
743	Pancreatic Pseudocyst	1.7%
744	Urticaria	1.7%
745	Ventricular Fibrillation	1.7%
746	Ventricular Flutter	1.7%
747	Parasystole	1.7%
748	Paroxysmal atrial fibrillation	1.7%
749	Bradycardia	1.7%
750	Diabetic Cardiomyopathies	1.7%
751	Cardiomyopathy, Alcoholic	1.6%
752	Ectopia Cordis	1.6%
753	HTLV-I Infections	1.6%
754	Lymphatic Metastasis	1.6%
755	Neoplasms, Unknown Primary	1.6%
756	Sudden Cardiac Death	1.6%
757	Left Ventricular Hypertrophy	1.6%
758	Leukemic Infiltration	1.6%
759	Right Ventricular Hypertrophy	1.6%
760	Breast Neoplasms, Male	1.6%
761	Single umbilical artery	1.6%
762	Neoplasm Micrometastasis	1.6%
763	Triple Negative Breast Neoplasms	1.6%
764	Chagas Cardiomyopathy	1.6%
765	Myasthenia Gravis, Autoimmune, Experimental	1.6%
766	Fabry Disease	1.6%
767	Nose Neoplasms	1.6%
768	Palatal Neoplasms	1.5%
769	Adrenal Gland Neoplasms	1.5%
770	Gastrointestinal Neoplasms	1.5%
771	Genital Neoplasms, Male	1.5%
772	Liver neoplasms	1.5%
773	Uveal Neoplasms	1.5%
774	Myasthenia Gravis	1.5%
775	Urologic Neoplasms	1.5%
776	Uveomeningoencephalitic Syndrome	1.5%
777	Drug Eruptions	1.5%
778	Sebaceous Gland Neoplasms	1.5%
779	Spinal Neoplasms	1.5%
780	Dyspnea, Paroxysmal	1.5%
781	Dermatitis, Allergic Contact	1.5%
782	HIV Seropositivity	1.5%
783	Polycystic Ovary Syndrome	1.5%
784	Pituitary Adenoma	1.4%
785	Pituitary Neoplasms	1.4%
786	Xeroderma Pigmentosum	1.4%
787	Aortic Valve Prolapse	1.4%
788	Tricuspid Valve Prolapse	1.4%
789	Milk Allergy	1.4%
790	Wheat Hypersensitivity	1.4%
791	Takotsubo Cardiomyopathy	1.4%
792	Turner Syndrome	1.4%
793	Stiff-Person Syndrome	1.3%
794	Polyradiculoneuropathy	1.3%
795	Polyradiculoneuritis	1.3%
796	Dural Arteriovenous Fistula	1.3%
797	Acquired Immunodeficiency Syndrome	1.3%
798	AIDS related complex	1.3%
799	Felty Syndrome	1.3%
800	Lupus Nephritis	1.3%
801	Neuromyelitis Optica	1.3%
802	Leukoencephalitis, Acute Hemorrhagic	1.3%
803	Meningeal Neoplasms	1.2%
804	Sinus Arrest, Cardiac	1.2%
805	AIDS-Related Opportunistic Infections	1.2%
806	Dermatitis, Atopic	1.2%
807	ovarian neoplasm	1.2%
808	HIV Wasting Syndrome	1.2%
809	AIDS Dementia Complex	1.2%
810	AIDS-Associated Nephropathy	1.2%
811	Ear Neoplasms	1.1%
812	Eyelid Neoplasms	1.1%
813	Lung Neoplasms	1.1%
814	Pleural Neoplasms	1.1%
815	Kartagener Syndrome	1.1%
816	Cell Transformation, Viral	1.1%
817	Brain Neoplasms	1.1%
818	Multiple Sclerosis	1.1%
819	Salivary Gland Neoplasms	1.1%
820	Spinal Cord Neoplasms	1.1%
821	Tongue Neoplasms	1.1%
822	Sicca Syndrome	1.1%
823	Sjogren's Syndrome	1.1%
824	Uterine Neoplasms	1.1%
825	Vaginal Neoplasms	1.1%
826	Vulvar Neoplasms	1.1%
827	Uterine Cancer	1.1%
828	Acute Generalized Exanthematous Pustulosis	1.1%
829	Fallopian Tube Neoplasms	1.1%
830	HIV-Associated Lipodystrophy Syndrome	1.1%
831	Meningeal Carcinomatosis	1%
832	Zollinger-Ellison syndrome	1%
833	Pharyngeal Neoplasms	1%
834	Asthma	1%
835	Central Nervous System Cysts	1%
836	Bile Duct Neoplasms	1%
837	gallbladder neoplasm	1%
838	Intestinal Neoplasms	1%
839	Penile Neoplasms	1%
840	Prostatic Neoplasms	1%
841	Stomach Neoplasms	1%
842	Encephalomyelitis, Acute Disseminated	1%
843	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	1%
844	Erythema Nodosum	1%
845	Neuritis, Autoimmune, Experimental	1%
846	Dermatitis, Photoallergic	1%
847	Laryngeal neoplasm	0.9%
848	Bronchial Neoplasms	0.9%
849	Asthma, Exercise-Induced	0.9%
850	Status Asthmaticus	0.9%
851	Multiple Pulmonary Nodules	0.9%
852	Supratentorial Neoplasms	0.9%
853	Multiple Sclerosis, Chronic Progressive	0.9%
854	Multiple Sclerosis, Relapsing-Remitting	0.9%
855	Endometrial Neoplasms	0.9%
856	Aspergillosis, Allergic Bronchopulmonary	0.9%
857	Guillain-Barre Syndrome	0.9%
858	Bladder Neoplasm	0.9%
859	Kidney Neoplasm	0.9%
860	Ureteral Neoplasms	0.9%
861	Urethral Neoplasms	0.9%
862	Asthma, Occupational	0.8%
863	Farmer's Lung	0.8%
864	Hypopharyngeal Neoplasms	0.8%
865	Pleural Effusion, Malignant	0.8%
866	Hypopharyngeal Cancer	0.8%
867	Williams Syndrome	0.8%
868	Hay fever	0.8%
869	Rhinitis, Allergic, Perennial	0.8%
870	Toxic Epidermal Necrolysis	0.8%
871	Stevens-Johnson Syndrome	0.8%
872	Parotid Neoplasms	0.8%
873	Prostatic Neoplasms, Castration-Resistant	0.8%
874	Nelson Syndrome	0.8%
875	Brain Stem Neoplasms	0.8%
876	Kearns-Sayre syndrome	0.8%
877	Choroid Plexus Papilloma	0.8%
878	Cecal Neoplasms	0.7%
879	Duodenal Neoplasms	0.7%
880	Tonsillar Neoplasms	0.7%
881	Cerebellar Neoplasms	0.7%
882	Nasopharyngeal Neoplasms	0.7%
883	Colorectal Neoplasms	0.7%
884	Radicular Cyst	0.7%
885	Appendiceal Neoplasms	0.7%
886	Colonic Neoplasms	0.7%
887	Rectal Neoplasms	0.7%
888	Paranasal Sinus Neoplasms	0.6%
889	Miller Fisher Syndrome	0.6%
890	Anus Neoplasms	0.6%
891	Sigmoid Neoplasms	0.6%
892	Maxillary Sinus Neoplasms	0.6%

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