MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Osteochondritis

(UMLS:C0029420)

Definition:: Inflammation of a bone and its overlaying CARTILAGE.
UMLS ID:: C0029420
MeSH ID:: D010007

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.116.791|C05.182.520

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.182.520

Synonym(s)

Osteochondritis

OSTEOCHONDRITIS

Osteochondritis, NOS

osteochondritis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Valproic Acid	FAERS: 5		US FAERS
2	Zoledronic Acid	FAERS: 4 Canada Vigilance: 1		Canada Vigilance US FAERS
3	Alendronate	FAERS: 3		US FAERS
4	Octreotide	FAERS: 3		US FAERS
5	Teriparatide	FAERS: 3		US FAERS
6	Capecitabine	FAERS: 1		US FAERS
7	Paroxetine	FAERS: 1		US FAERS
8	Phenytoin	FAERS: 1		US FAERS
9	Valsartan	FAERS: 1		US FAERS
10	Chlorhexidine		9619932	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Pectus carinatum	43.1%
2	Tietze's Syndrome	41.7%
3	Osteoarthropathy, Secondary Hypertrophic	33.8%
4	Rheumatism	30.4%
5	Platybasia	29%
6	Bone Diseases, Developmental	28.1%
7	Hyperostosis	28.1%
8	Osteitis	28.1%
9	Osteitis Deformans	28.1%
10	Osteochondrosis	28.1%
11	Spinal Diseases	28.1%
12	Gigantism	27.3%
13	Spinal Neoplasms	27.3%
14	Spondylitis	27.3%
15	Laryngomalacia	26.1%
16	Polymyalgia Rheumatica	25.6%
17	Arthrogryposis	24%
18	Osteoarthritis, Spine	23.9%
19	Bone Diseases, Endocrine	23.2%
20	Pectus excavatum	23%
21	Bone Diseases, Infectious	22.5%
22	Bone neoplasms	22.5%
23	Contracture	22.5%
24	Osteopenia	22.5%
25	Fasciitis, Plantar	22.5%
26	Discitis	22.3%
27	Bone Resorption	22.2%
28	Aseptic Necrosis of Bone	22.2%
29	Fasciitis	21.8%
30	Foot Deformities	21.8%
31	Arthropathy	21.8%
32	Foot Diseases	21.7%
33	Bronchomalacia	21.6%
34	Tracheomalacia	21.6%
35	Ankylosing spondylitis	21.2%
36	Ainhum	20.7%
37	Dysostoses	20.7%
38	Spinal Stenosis	20.7%
39	Spondylosis	20.7%
40	Intervertebral Disc Degeneration	20.7%
41	Klippel-Feil Syndrome	20.6%
42	Synostosis	20.6%
43	Rheumatoid Arthritis	19.8%
44	Juvenile arthritis	19.8%
45	Arthritis, Psoriatic	19.5%
46	Tuberculosis, Spinal	19%
47	Spondylarthropathies	18.9%
48	Congenital Hypothyroidism	18.7%
49	Fibromyalgia	18.6%
50	Acrocephalosyndactylia	18.5%
51	Metatarsalgia	18.5%
52	Osteogenesis Imperfecta	18.3%
53	Craniofacial Dysostosis	18%
54	Jaw Diseases	17.9%
55	Craniosynostosis	17.5%
56	Syndactyly	17.5%
57	Brachycephaly	17.5%
58	Ischemic contracture	17.5%
59	Rheumatoid Nodule	17.4%
60	Myopathy	17.4%
61	Arthritis, Reactive	17.1%
62	Chondrodysplasia Punctata	17.1%
63	Enchondromatosis	17.1%
64	Lordosis	17.1%
65	Osteosclerosis	17.1%
66	Spondylolysis	17.1%
67	kyphosis	17.1%
68	Kashin-Beck Disease	17.1%
69	Dupuytren Contracture	17.1%
70	Gout	16.9%
71	Lupus Erythematosus, Cutaneous	16.9%
72	Panniculitis	16.9%
73	Systemic Scleroderma	16.9%
74	Morphea	16.9%
75	Multiple Epiphyseal Dysplasia	16.7%
76	Osteochondrodysplasias	16.7%
77	Dermatomyositis	16.6%
78	Temporomandibular Joint Disorders	16.5%
79	Hip Contracture	16.4%
80	Osteomyelitis	16.4%
81	Osteoporosis	16.4%
82	Periarthritis	16.4%
83	Periostitis	16.4%
84	Bone Demineralization, Pathologic	16.4%
85	Post-Traumatic Osteoporosis	16.4%
86	Alveolar Bone Loss	16.3%
87	Femur Head Necrosis	16.3%
88	Osteolysis	16.3%
89	Temporomandibular Joint Dysfunction Syndrome	16%
90	Rheumatic Fever	16%
91	Collagen Diseases	15.8%
92	Mixed Connective Tissue Disease	15.8%
93	Mucinoses	15.8%
94	Talipes	15.8%
95	Melorheostosis	15.3%
96	Osteopetrosis	15.3%
97	Spondylolisthesis	15.3%
98	Poland Syndrome	15.2%
99	Osteoarthritis, Knee	15%
100	Felty Syndrome	14.9%
101	Goldenhar Syndrome	14.4%
102	Marfan Syndrome	14.3%
103	Dwarfism	14.3%
104	Arthritis	14%
105	Bursitis	14%
106	Joint Instability	14%
107	Myofascial Pain Syndromes	14%
108	Rhabdomyolysis	14%
109	Synovitis	14%
110	Joint laxity	14%
111	Polyarthritis	14%
112	Frozen shoulder	14%
113	Patellofemoral Pain Syndrome	14%
114	Osteoporosis, Postmenopausal	13.5%
115	Acromegaly	13.5%
116	Eosinophilic Granuloma	13.5%
117	Joint Tuberculosis	13.5%
118	Tuberculosis, Osteoarticular	13.5%
119	Bone Tuberculosis	13.5%
120	Congenital clubfoot	13.5%
121	Vertical Talus	13.5%
122	Panniculitis, Lupus Erythematosus	13.5%
123	Mandibulofacial Dysostosis	13.3%
124	Arthritis, Gouty	13.3%
125	Rheumatoid Vasculitis	13%
126	Lupus Erythematosus, Systemic	12.7%
127	Overlap syndrome	12.7%
128	Cutis Laxa	12.6%
129	Antley-Bixler Syndrome Phenotype	12.5%
130	Rickets	11.6%
131	Sicca Syndrome	11.5%
132	Sjogren's Syndrome	11.5%
133	Noonan Syndrome	11.3%
134	Compartment syndromes	11.3%
135	Maxillary Diseases	11.3%
136	Tendinitis	11.3%
137	Tendinopathy	11.3%
138	Mastoiditis	11.2%
139	Petrositis	11.2%
140	Hemarthrosis	11.1%
141	Myositis	11.1%
142	Palatal Neoplasms	11.1%
143	Limb Deformities, Congenital	11.1%
144	Isaacs syndrome	11.1%
145	Craniofacial Abnormalities	11.1%
146	Myotonic Disorders	11.1%
147	Lupus Erythematosus, Discoid	11%
148	Scleroderma, Limited	11%
149	Bone Diseases	10.9%
150	Rubinstein-Taybi Syndrome	10.7%
151	Bunion	10.3%
152	Fibrodysplasia Ossificans Progressiva	10.3%
153	Myoglobinuria	10.3%
154	Myositis Ossificans	10.3%
155	Tenosynovitis	10.3%
156	Scleromyxedema	10.3%
157	Sacroiliitis	10.3%
158	Pseudohypoparathyroidism	10.1%
159	Prognathism	9.9%
160	Nail-Patella Syndrome	9.9%
161	Jaw Abnormalities	9.8%
162	Osteomalacia	9.5%
163	Basal Cell Nevus Syndrome	9.4%
164	Osteochondritis	9.3%
165	Medial Tibial Stress Syndrome	9.3%
166	Mitochondrial Myopathies	9.2%
167	Muscle Cramp	9.1%
168	Eosinophilia-Myalgia Syndrome	9.1%
169	Gastroschisis	9.1%
170	Muscle Rigidity	9.1%
171	Muscle Spasticity	9.1%
172	Cogwheel Rigidity	9.1%
173	Nuchal Rigidity	9.1%
174	Pseudoxanthoma Elasticum	8.8%
175	Cellulitis	8.8%
176	Cartilage Diseases	8.7%
177	Chondromalacia	8.7%
178	Arthritis, Infectious	8.3%
179	Mesenteric Panniculitis	8.3%
180	Panniculitis, Peritoneal	8.3%
181	Orbital Cellulitis	8.3%
182	Myxoid cyst	8.3%
183	Anterior Compartment Syndrome	8.2%
184	Myxedema	8.2%
185	Enthesopathy	8.2%
186	Arthritis, Experimental	8.2%
187	Abdominal Compartment Syndrome	8.2%
188	Necrobiosis Lipoidica Diabeticorum	8.2%
189	Amelia	8.2%
190	Arachnodactyly	8.2%
191	Ectromelia	8.2%
192	Chronic Fatigue Syndrome	8.2%
193	Hemimelia	8.2%
194	Phocomelia	8.2%
195	Sirenomelia	8.2%
196	Polymyositis	8.2%
197	Polydactyly	8.2%
198	Brachydactyly	8.2%
199	Plagiocephaly	8.2%
200	Lower Extremity Deformities, Congenital	8.2%
201	Upper Extremity Deformities, Congenital	8.2%
202	Giant Cell Epulis	7.9%
203	Muscle Weakness	7.9%
204	Musculoskeletal Pain	7.8%
205	Familial Periodic Paralysis	7.8%
206	Arthralgia	7.7%
207	Polyarthralgia	7.7%
208	Micrognathism	7.7%
209	Pierre Robin Syndrome	7.7%
210	Cockayne Syndrome	7.5%
211	Erythema Induratum	7.5%
212	Myotonic Dystrophy	7.3%
213	Granuloma Annulare	7.3%
214	Hip Dislocation	7%
215	Shoulder Dislocation	7%
216	Hip Dysplasia	7%
217	Retrognathia	7%
218	Nose Neoplasms	6.9%
219	Muscular Dystrophy	6.9%
220	Orbital Myositis	6.9%
221	Pyoderma Gangrenosum	6.8%
222	Pyomyositis	6.8%
223	Keloid	6.7%
224	Myalgia	6.7%
225	Renal Osteodystrophy	6.6%
226	Renal rickets	6.6%
227	Homocystinuria	6%
228	Maxillofacial Abnormalities	5.9%
229	Myotonia Congenita	5.8%
230	Cleft Palate	5.8%
231	Lupus Nephritis	5.7%
232	Microcephaly	5.7%
233	Macrocephaly	5.7%
234	Hypokalemic periodic paralysis	5.7%
235	Shoulder Pain	5.7%
236	Welander Distal Myopathy	5.6%
237	Acne Vulgaris	5.5%
238	Contact Dermatitis	5.5%
239	Eczema	5.5%
240	Erythema Multiforme	5.5%
241	Intertrigo	5.5%
242	Neurodermatitis	5.5%
243	Rhinophyma	5.5%
244	Perioral Dermatitis	5.5%
245	Acne	5.5%
246	Breast Diseases	5.3%
247	Dermatitis	5.3%
248	Exanthema	5.3%
249	Facial Dermatoses	5.3%
250	Hair Diseases	5.3%
251	Hand Dermatoses	5.3%
252	keratoacanthoma	5.3%
253	Keratosis	5.3%
254	Nail Diseases	5.3%
255	Photosensitivity Disorders	5.3%
256	Prurigo	5.3%
257	Pyoderma	5.3%
258	Rosacea	5.3%
259	Sebaceous Gland Diseases	5.3%
260	Skin Diseases, Vesiculobullous	5.3%
261	Skin Ulcer	5.3%
262	Sweat Gland Diseases	5.3%
263	Skin Diseases, Papulosquamous	5.3%
264	Skin Diseases, Vascular	5.3%
265	Acneiform Eruptions	5.3%
266	Ocular Rosacea	5.3%
267	Subcorneal pustular dermatosis	5.3%
268	Erythematotelangiectatic Rosacea	5.3%
269	Papulopustular Rosacea	5.3%
270	Chronic Actinic Dermatitis	5.3%
271	Dermatitis, Atopic	5.1%
272	Epidermolysis Bullosa	5.1%
273	Dermatitis, Phototoxic	5%
274	Pityriasis Lichenoides et Varioliformis Acuta	5%
275	Pityriasis Lichenoides	5%
276	Phototoxicity	5%
277	Mitochondrial Encephalomyopathies	5%
278	Xeroderma Pigmentosum	4.9%
279	Muscular Dystrophy, Duchenne	4.8%
280	Foot Ulcer	4.8%
281	Porencephaly	4.7%
282	Dermatitis Herpetiformis	4.6%
283	Acrodermatitis	4.5%
284	Sebaceous Gland Neoplasms	4.5%
285	Porokeratosis	4.5%
286	Gianotti-Crosti Syndrome	4.5%
287	Keratoderma, Palmoplantar	4.5%
288	CREST Syndrome	4.4%
289	Dermatitis, Photoallergic	4.3%
290	Skin Abnormalities	4.2%
291	Skin Diseases, Infectious	4.2%
292	Skin Neoplasms	4.2%
293	Pigmentation Disorders	4.2%
294	Lipomatosis	4.2%
295	Pruritus	4.2%
296	Erythema	4.2%
297	Necrolytic Migratory Erythema	4.2%
298	Cutaneous Fistula	4.2%
299	Nephrogenic Fibrosing Dermopathy	4.2%
300	Nephrogenic Systemic Fibrosis	4.2%
301	Dermatitis, Irritant	4.1%
302	Acne Conglobata	4.1%
303	Holoprosencephaly	4%
304	Xeroderma	3.9%
305	Urticaria Pigmentosa	3.9%
306	Familial Hypophosphatemic Rickets	3.9%
307	Radicular Cyst	3.7%
308	Mucopolysaccharidosis III	3.7%
309	Dermatitis, Occupational	3.5%
310	Anhidrosis	3.4%
311	Cholesteatoma	3.4%
312	Pressure Ulcer	3.4%
313	Folliculitis	3.4%
314	Foot Dermatoses	3.4%
315	Gynecomastia	3.4%
316	Hypertrichosis	3.4%
317	Hypohidrosis	3.4%
318	Hypotrichosis	3.4%
319	Leg Ulcer	3.4%
320	Miliaria	3.4%
321	Parakeratosis	3.4%
322	Parapsoriasis	3.4%
323	Pityriasis	3.4%
324	Psoriasis	3.4%
325	Sweet Syndrome	3.4%
326	Hidradenitis	3.4%
327	Onycholysis	3.4%
328	Miliaria Rubra	3.4%
329	Hyperpigmentation	3.4%
330	Lichenoid Eruptions	3.4%
331	Chloracne	3.4%
332	Mastocytosis	3.4%
333	Erythema Infectiosum	3.4%
334	Exanthema Subitum	3.4%
335	Ectodermal Dysplasia	3.4%
336	Aplasia Cutis Congenita	3.4%
337	Dermatitis, Allergic Contact	3.4%
338	Diaper Rash	3.4%
339	Papillon-Lefevre Disease	3.4%
340	Erythema Nodosum	3.3%
341	Toxic Epidermal Necrolysis	3.3%
342	Stevens-Johnson Syndrome	3.3%
343	Tinea Capitis	3.1%
344	Onychomycosis	3.1%
345	Ecthyma	2.9%
346	Hyperkeratosis, Epidermolytic	2.9%
347	Lupus Vasculitis, Central Nervous System	2.8%
348	Acantholysis	2.8%
349	Breast Cyst	2.8%
350	Actinic keratosis	2.8%
351	Pemphigoid, Benign Mucous Membrane	2.8%
352	Pemphigus	2.8%
353	Piedra	2.8%
354	Sunburn	2.8%
355	Ichthyosis, X-Linked	2.8%
356	Sjogren-Larsson Syndrome	2.8%
357	Argyria	2.7%
358	Hirsutism	2.7%
359	Lactation Disorder	2.7%
360	Mastitis	2.7%
361	Urticaria	2.7%
362	MELAS Syndrome	2.7%
363	Adiposis Dolorosa	2.7%
364	Pruritus Vulvae	2.7%
365	Mastocytoma	2.7%
366	Pruritus Ani	2.7%
367	Mucopolysaccharidosis II	2.7%
368	Behcet Syndrome	2.6%
369	Lichen Planus	2.6%
370	Melanosis	2.6%
371	Chloasma	2.6%
372	Pityriasis Rosea	2.6%
373	Pityriasis Rubra Pilaris	2.6%
374	Vitiligo	2.6%
375	Lichen Nitidus	2.6%
376	Kearns-Sayre syndrome	2.5%
377	Hidradenitis Suppurativa	2.5%
378	Albinism	2.4%
379	Erythema Chronicum Migrans	2.3%
380	Dermatomycoses	2.3%
381	Mucocutaneous Lymph Node Syndrome	2.3%
382	Skin Diseases, Bacterial	2.3%
383	Drug Eruptions	2.3%
384	Lipodystrophy	2.3%
385	Tinea Pedis	2.3%
386	Livedo Reticularis	2.3%
387	Malignant Atrophic Papulosis	2.3%
388	Polyarteritis Nodosa	2.2%
389	Takayasu Arteritis	2.2%
390	Acanthosis Nigricans	2.1%
391	Alopecia Areata	2.1%
392	Lentigo	2.1%
393	Alopecia	2.1%
394	Sweating, Gustatory	2.1%
395	Androgenetic Alopecia	2.1%
396	Auriculotemporal Syndrome	2.1%
397	Lice Infestations	2%
398	Varicose Ulcer	2%
399	Breast Neoplasms, Male	2%
400	Triple Negative Breast Neoplasms	2%
401	Galactorrhea	2%
402	Mycetoma	2%
403	Porphyrias, Hepatic	2%
404	Lichen Planus, Oral	1.7%
405	Larva Migrans	1.7%
406	Leishmaniasis	1.7%
407	Molluscum Contagiosum	1.7%
408	Angioedema	1.7%
409	Onchocerciasis	1.7%
410	Chromoblastomycosis	1.7%
411	Dermatophytosis	1.7%
412	Sporotrichosis	1.7%
413	Tinea	1.7%
414	Tinea Versicolor	1.7%
415	Trichophytosis	1.7%
416	Hyalohyphomycosis	1.7%
417	Acute Generalized Exanthematous Pustulosis	1.7%
418	Warts	1.5%
419	Candidiasis, Chronic Mucocutaneous	1.4%
420	Cutaneous Candidiasis	1.4%
421	Erysipelas	1.4%
422	Serum Sickness	1.4%
423	Staphylococcal Skin Infections	1.4%
424	Variegate Porphyria	1.4%
425	Acute intermittent porphyria	1.4%
426	Porphyria Cutanea Tarda	1.4%
427	Erythrasma	1.4%
428	Carcinoma, Lobular	1.4%
429	Leishmaniasis, Cutaneous	1.4%
430	Eczema Herpeticum	1.4%
431	Fusariosis	1.4%
432	Giant Cell Arteritis	1.3%
433	Temporal Arteritis	1.3%
434	Hereditary Angioedema Type III	1.2%
435	Hereditary Angioedema Types I and II	1.2%
436	Angioedemas, Hereditary	1.2%
437	Epidermodysplasia Verruciformis	1.2%
438	Herpes Labialis	1.2%
439	Diabetic Foot	1.2%
440	Staphylococcal Scalded Skin Syndrome	1.2%
441	Blastomycosis	1.1%
442	HIV-Associated Lipodystrophy Syndrome	1.1%
443	Peutz-Jeghers Syndrome	1.1%
444	carbuncle	1.1%
445	Condylomata Acuminata	1%
446	Furunculosis	1%
447	furuncle	1%
448	Impetigo	1%
449	Rhinoscleroma	1%
450	Menkes Kinky Hair Syndrome	1%

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