MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Rheumatism

(UMLS:C0035435)

Definition:: Disorders of connective tissue, especially the joints and related structures, characterized by inflammation, degeneration, or metabolic derangement.
UMLS ID:: C0035435
MeSH ID:: D012216

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.799

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.775

Synonym(s)

Rheumatism

Locomotor pain disorder

Musculoskeletal pain disorder

RHEUMATIC

RHEUMATISM

Rheumatism, NOS

Rheumatism, unspecified

Rheumatism, unspecified, site unspecified

rheumatic disease

10.

rheumatic diseases

11.

rheumatics

12.

rheumatism

Associated Drug(s)

	Name	Data Source
1	Fluticasone	SIDER
2	Salmeterol Xinafoate	SIDER
3	Zanamivir	SIDER
4	naratriptan	SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Cartilage Diseases	38.5%
2	Chondromalacia	38.5%
3	Osteochondritis	30.4%
4	Collagen Diseases	30%
5	Mixed Connective Tissue Disease	30%
6	Mucinoses	30%
7	Lupus Erythematosus, Cutaneous	29.6%
8	Panniculitis	29.6%
9	Systemic Scleroderma	29.6%
10	Morphea	29.6%
11	Tietze's Syndrome	27.3%
12	Pectus carinatum	26.3%
13	Panniculitis, Lupus Erythematosus	25.3%
14	Dermatomyositis	24%
15	Dupuytren Contracture	24%
16	Foot Diseases	23.1%
17	Contracture	22.2%
18	Lupus Erythematosus, Systemic	22.2%
19	Osteoarthropathy, Secondary Hypertrophic	22.2%
20	Fasciitis, Plantar	22.2%
21	Overlap syndrome	22.2%
22	Scleromyxedema	22%
23	Arthrogryposis	21.7%
24	Cutis Laxa	21.4%
25	Lupus Erythematosus, Discoid	21.4%
26	Scleroderma, Limited	21.4%
27	Bone Diseases	21.1%
28	Fasciitis	21.1%
29	Foot Deformities	21.1%
30	Arthropathy	21.1%
31	Osteogenesis Imperfecta	19.1%
32	Ankylosing spondylitis	18.4%
33	Arthritis, Psoriatic	18%
34	Hip Contracture	17.9%
35	Periarthritis	17.9%
36	Ischemic contracture	17.4%
37	Platybasia	17.3%
38	Metatarsalgia	17.3%
39	Mesenteric Panniculitis	16.4%
40	Panniculitis, Peritoneal	16.4%
41	Orbital Cellulitis	16.4%
42	Myxoid cyst	16.4%
43	Talipes	16.3%
44	Myxedema	16.1%
45	Temporomandibular Joint Dysfunction Syndrome	16%
46	Jaw Diseases	16%
47	Temporomandibular Joint Disorders	15.8%
48	Pectus excavatum	15.7%
49	Necrobiosis Lipoidica Diabeticorum	15.6%
50	Myopathy	15.4%
51	Laryngomalacia	15.3%
52	Spondylarthropathies	15.3%
53	Osteoarthritis, Spine	15.1%
54	Arthritis	15%
55	Bone Diseases, Developmental	15%
56	Bursitis	15%
57	Hyperostosis	15%
58	Joint Instability	15%
59	Myofascial Pain Syndromes	15%
60	Osteitis	15%
61	Osteitis Deformans	15%
62	Osteochondrosis	15%
63	Rhabdomyolysis	15%
64	Spinal Diseases	15%
65	Synovitis	15%
66	Joint laxity	15%
67	Polyarthritis	15%
68	Frozen shoulder	15%
69	Patellofemoral Pain Syndrome	15%
70	Klippel-Feil Syndrome	14.9%
71	Synostosis	14.9%
72	Congenital clubfoot	14.8%
73	Vertical Talus	14.8%
74	Granuloma Annulare	14.7%
75	Noonan Syndrome	14.7%
76	Arthritis, Reactive	14.6%
77	Bronchomalacia	14.4%
78	Tracheomalacia	14.4%
79	Acrocephalosyndactylia	14.4%
80	Gigantism	14.1%
81	Spinal Neoplasms	14.1%
82	Spondylitis	14.1%
83	Cellulitis	14%
84	Craniosynostosis	13.9%
85	Syndactyly	13.9%
86	Brachycephaly	13.9%
87	Pseudoxanthoma Elasticum	13.8%
88	Craniofacial Dysostosis	13.2%
89	Marfan Syndrome	13.1%
90	Erythema Induratum	12.9%
91	Pyoderma Gangrenosum	12.7%
92	Poland Syndrome	12.6%
93	Keloid	12.5%
94	Discitis	12.4%
95	Ainhum	12.2%
96	Bunion	12.2%
97	Dysostoses	12.2%
98	Fibrodysplasia Ossificans Progressiva	12.2%
99	Myoglobinuria	12.2%
100	Myositis Ossificans	12.2%
101	Spinal Stenosis	12.2%
102	Spondylosis	12.2%
103	Tenosynovitis	12.2%
104	Intervertebral Disc Degeneration	12.2%
105	Sacroiliitis	12.2%
106	Bone Diseases, Endocrine	11.5%
107	Goldenhar Syndrome	11.4%
108	Bone Diseases, Infectious	11.1%
109	Bone neoplasms	11.1%
110	Compartment syndromes	11.1%
111	Maxillary Diseases	11.1%
112	Osteopenia	11.1%
113	Tendinitis	11.1%
114	Tendinopathy	11.1%
115	Bone Resorption	10.9%
116	Hemarthrosis	10.9%
117	Myositis	10.9%
118	Limb Deformities, Congenital	10.9%
119	Isaacs syndrome	10.9%
120	Craniofacial Abnormalities	10.9%
121	Aseptic Necrosis of Bone	10.9%
122	Myotonic Disorders	10.9%
123	Chondrodysplasia Punctata	10.8%
124	Enchondromatosis	10.8%
125	Lordosis	10.8%
126	Osteosclerosis	10.8%
127	Spondylolysis	10.8%
128	kyphosis	10.8%
129	Kashin-Beck Disease	10.8%
130	Acne Vulgaris	10.7%
131	Contact Dermatitis	10.7%
132	Eczema	10.7%
133	Erythema Multiforme	10.7%
134	Intertrigo	10.7%
135	Nail-Patella Syndrome	10.7%
136	Neurodermatitis	10.7%
137	Rhinophyma	10.7%
138	Perioral Dermatitis	10.7%
139	Acne	10.7%
140	Dermatitis, Phototoxic	10.3%
141	Pityriasis Lichenoides et Varioliformis Acuta	10.3%
142	Pityriasis Lichenoides	10.3%
143	Phototoxicity	10.3%
144	Lupus Nephritis	10.3%
145	Melorheostosis	10.2%
146	Osteopetrosis	10.2%
147	Spondylolisthesis	10.2%
148	Tuberculosis, Spinal	10.2%
149	Breast Diseases	10%
150	Dermatitis	10%
151	Exanthema	10%
152	Facial Dermatoses	10%
153	Hair Diseases	10%
154	Hand Dermatoses	10%
155	keratoacanthoma	10%
156	Keratosis	10%
157	Nail Diseases	10%
158	Photosensitivity Disorders	10%
159	Prurigo	10%
160	Pyoderma	10%
161	Rosacea	10%
162	Sebaceous Gland Diseases	10%
163	Skin Diseases, Vesiculobullous	10%
164	Skin Ulcer	10%
165	Sweat Gland Diseases	10%
166	Skin Diseases, Papulosquamous	10%
167	Skin Diseases, Vascular	10%
168	Acneiform Eruptions	10%
169	Ocular Rosacea	10%
170	Subcorneal pustular dermatosis	10%
171	Erythematotelangiectatic Rosacea	10%
172	Papulopustular Rosacea	10%
173	Chronic Actinic Dermatitis	10%
174	Mandibulofacial Dysostosis	9.9%
175	Gout	9.9%
176	Foot Ulcer	9.7%
177	Prognathism	9.6%
178	Congenital Hypothyroidism	9.5%
179	Arthritis, Infectious	9.1%
180	Multiple Epiphyseal Dysplasia	9.1%
181	Osteochondrodysplasias	9.1%
182	Jaw Abnormalities	9.1%
183	Homocystinuria	9%
184	Antley-Bixler Syndrome Phenotype	9%
185	Anterior Compartment Syndrome	8.9%
186	Osteomyelitis	8.9%
187	Osteoporosis	8.9%
188	Periostitis	8.9%
189	Enthesopathy	8.9%
190	Bone Demineralization, Pathologic	8.9%
191	Post-Traumatic Osteoporosis	8.9%
192	Arthritis, Experimental	8.9%
193	Abdominal Compartment Syndrome	8.9%
194	Dermatitis, Atopic	8.9%
195	Epidermolysis Bullosa	8.9%
196	Alveolar Bone Loss	8.8%
197	Amelia	8.8%
198	Arachnodactyly	8.8%
199	Ectromelia	8.8%
200	Femur Head Necrosis	8.8%
201	Hemimelia	8.8%
202	Phocomelia	8.8%
203	Sirenomelia	8.8%
204	Polymyositis	8.8%
205	Polydactyly	8.8%
206	Brachydactyly	8.8%
207	Plagiocephaly	8.8%
208	Lower Extremity Deformities, Congenital	8.8%
209	Upper Extremity Deformities, Congenital	8.8%
210	Osteolysis	8.8%
211	Dermatitis, Irritant	8.8%
212	Acne Conglobata	8.8%
213	Arthritis, Gouty	8.7%
214	Fibromyalgia	8.7%
215	Polymyalgia Rheumatica	8.7%
216	Medial Tibial Stress Syndrome	8.7%
217	Dermatitis Herpetiformis	8.6%
218	Mitochondrial Myopathies	8.6%
219	Dermatitis, Photoallergic	8.5%
220	Muscle Cramp	8.5%
221	Eosinophilia-Myalgia Syndrome	8.5%
222	Gastroschisis	8.5%
223	Acrodermatitis	8.5%
224	Sebaceous Gland Neoplasms	8.5%
225	Porokeratosis	8.5%
226	Gianotti-Crosti Syndrome	8.5%
227	Keratoderma, Palmoplantar	8.5%
228	Muscle Rigidity	8.4%
229	Muscle Spasticity	8.4%
230	Cogwheel Rigidity	8.4%
231	CREST Syndrome	8.4%
232	Nuchal Rigidity	8.4%
233	Xeroderma Pigmentosum	8.3%
234	Osteoarthritis, Knee	8%
235	Osteoporosis, Postmenopausal	7.9%
236	Palatal Neoplasms	7.8%
237	Diaper Rash	7.8%
238	Micrognathism	7.8%
239	Pierre Robin Syndrome	7.8%
240	Urticaria Pigmentosa	7.6%
241	Dwarfism	7.5%
242	Chronic Fatigue Syndrome	7.4%
243	Skin Abnormalities	7.4%
244	Skin Diseases, Infectious	7.4%
245	Skin Neoplasms	7.4%
246	Pigmentation Disorders	7.4%
247	Anhidrosis	7.3%
248	Cholesteatoma	7.3%
249	Pressure Ulcer	7.3%
250	Folliculitis	7.3%
251	Foot Dermatoses	7.3%
252	Gynecomastia	7.3%
253	Hypertrichosis	7.3%
254	Hypohidrosis	7.3%
255	Hypotrichosis	7.3%
256	Leg Ulcer	7.3%
257	Miliaria	7.3%
258	Parakeratosis	7.3%
259	Parapsoriasis	7.3%
260	Pityriasis	7.3%
261	Psoriasis	7.3%
262	Sweet Syndrome	7.3%
263	Hidradenitis	7.3%
264	Onycholysis	7.3%
265	Miliaria Rubra	7.3%
266	Hyperpigmentation	7.3%
267	Lichenoid Eruptions	7.3%
268	Chloracne	7.3%
269	Lipomatosis	7.3%
270	Pruritus	7.3%
271	Erythema	7.3%
272	Necrolytic Migratory Erythema	7.3%
273	Cutaneous Fistula	7.3%
274	Nephrogenic Fibrosing Dermopathy	7.3%
275	Nephrogenic Systemic Fibrosis	7.3%
276	Hip Dislocation	7.2%
277	Dermatitis, Occupational	7.2%
278	Shoulder Dislocation	7.2%
279	Hip Dysplasia	7.2%
280	Mucopolysaccharidosis III	7.2%
281	Rubinstein-Taybi Syndrome	7.2%
282	Myotonic Dystrophy	7.2%
283	Giant Cell Epulis	7.1%
284	Muscle Weakness	7.1%
285	Muscular Dystrophy	7.1%
286	Rheumatic Fever	7.1%
287	Orbital Myositis	7.1%
288	Xeroderma	7.1%
289	Musculoskeletal Pain	7%
290	Pyomyositis	7%
291	Familial Periodic Paralysis	7%
292	Acromegaly	7%
293	Joint Tuberculosis	7%
294	Tuberculosis, Osteoarticular	7%
295	Bone Tuberculosis	7%
296	Dermatitis, Allergic Contact	6.9%
297	Arthralgia	6.9%
298	Polyarthralgia	6.9%
299	Retrognathia	6.9%
300	Papillon-Lefevre Disease	6.9%
301	Erythema Infectiosum	6.4%
302	Exanthema Subitum	6.4%
303	Toxic Epidermal Necrolysis	6.3%
304	Stevens-Johnson Syndrome	6.3%
305	Erythema Nodosum	6.3%
306	Rheumatoid Nodule	6.2%
307	Welander Distal Myopathy	6.2%
308	Mastoiditis	6.2%
309	Petrositis	6.2%
310	Lichen Planus	6%
311	Melanosis	6%
312	Chloasma	6%
313	Pityriasis Rosea	6%
314	Pityriasis Rubra Pilaris	6%
315	Vitiligo	6%
316	Lichen Nitidus	6%
317	Tinea Capitis	6%
318	Onychomycosis	6%
319	Rheumatoid Arthritis	6%
320	Juvenile arthritis	6%
321	Ectodermal Dysplasia	5.9%
322	Aplasia Cutis Congenita	5.9%
323	Eosinophilic Granuloma	5.9%
324	Myalgia	5.9%
325	Maxillofacial Abnormalities	5.8%
326	Hyperkeratosis, Epidermolytic	5.8%
327	Basal Cell Nevus Syndrome	5.8%
328	Myotonia Congenita	5.8%
329	Rickets	5.8%
330	Microcephaly	5.7%
331	Macrocephaly	5.7%
332	Hypokalemic periodic paralysis	5.7%
333	Mastocytosis	5.7%
334	Shoulder Pain	5.7%
335	Cleft Palate	5.6%
336	Acantholysis	5.5%
337	Breast Cyst	5.5%
338	Actinic keratosis	5.5%
339	Pemphigoid, Benign Mucous Membrane	5.5%
340	Pemphigus	5.5%
341	Piedra	5.5%
342	Sunburn	5.5%
343	Acanthosis Nigricans	5.4%
344	Alopecia Areata	5.4%
345	Lentigo	5.4%
346	Ecthyma	5.4%
347	Argyria	5.4%
348	Hirsutism	5.4%
349	Lactation Disorder	5.4%
350	Mastitis	5.4%
351	Urticaria	5.4%
352	Adiposis Dolorosa	5.3%
353	Pruritus Vulvae	5.3%
354	Mastocytoma	5.3%
355	Pruritus Ani	5.3%
356	Felty Syndrome	5.2%
357	Muscular Dystrophy, Duchenne	5.2%
358	Osteomalacia	5.1%
359	Porencephaly	5.1%
360	Mucopolysaccharidosis II	5%
361	Pseudohypoparathyroidism	4.9%
362	Ichthyosis, X-Linked	4.9%
363	Mitochondrial Encephalomyopathies	4.9%
364	Hidradenitis Suppurativa	4.9%
365	Sjogren-Larsson Syndrome	4.9%
366	Behcet Syndrome	4.7%
367	Lupus Vasculitis, Central Nervous System	4.6%
368	Tinea Pedis	4.6%
369	Alopecia	4.5%
370	Sweating, Gustatory	4.5%
371	Androgenetic Alopecia	4.5%
372	Auriculotemporal Syndrome	4.5%
373	Lice Infestations	4.4%
374	Varicose Ulcer	4.4%
375	Breast Neoplasms, Male	4.4%
376	Triple Negative Breast Neoplasms	4.4%
377	Rheumatoid Vasculitis	4.4%
378	Galactorrhea	4.4%
379	Dermatomycoses	4.3%
380	Mucocutaneous Lymph Node Syndrome	4.3%
381	Skin Diseases, Bacterial	4.3%
382	Drug Eruptions	4.2%
383	Lipodystrophy	4.2%
384	Livedo Reticularis	4.2%
385	Malignant Atrophic Papulosis	4.2%
386	Albinism	4.2%
387	Polyarteritis Nodosa	4.2%
388	Takayasu Arteritis	4.2%
389	Erythema Chronicum Migrans	4.1%
390	Radicular Cyst	4.1%
391	Lichen Planus, Oral	4%
392	Cockayne Syndrome	3.9%
393	Sicca Syndrome	3.8%
394	Sjogren's Syndrome	3.8%
395	Holoprosencephaly	3.8%
396	Mycetoma	3.7%
397	Larva Migrans	3.5%
398	Leishmaniasis	3.5%
399	Molluscum Contagiosum	3.5%
400	Porphyrias, Hepatic	3.5%
401	Angioedema	3.5%
402	Onchocerciasis	3.5%
403	Nose Neoplasms	3.5%
404	Chromoblastomycosis	3.5%
405	Dermatophytosis	3.5%
406	Sporotrichosis	3.5%
407	Tinea	3.5%
408	Tinea Versicolor	3.5%
409	Trichophytosis	3.5%
410	Hyalohyphomycosis	3.5%
411	Acute Generalized Exanthematous Pustulosis	3.4%
412	Renal Osteodystrophy	3.3%
413	Renal rickets	3.3%
414	Leishmaniasis, Cutaneous	3.1%
415	Eczema Herpeticum	3.1%
416	Fusariosis	3.1%
417	Warts	3%
418	Hereditary Angioedema Type III	2.9%
419	Hereditary Angioedema Types I and II	2.9%
420	Candidiasis, Chronic Mucocutaneous	2.9%
421	Cutaneous Candidiasis	2.9%
422	Erysipelas	2.9%
423	Serum Sickness	2.9%
424	Staphylococcal Skin Infections	2.9%
425	Variegate Porphyria	2.9%
426	Acute intermittent porphyria	2.9%
427	Porphyria Cutanea Tarda	2.9%
428	Erythrasma	2.8%
429	Carcinoma, Lobular	2.8%
430	MELAS Syndrome	2.7%
431	Angioedemas, Hereditary	2.6%
432	Epidermodysplasia Verruciformis	2.6%
433	Herpes Labialis	2.6%
434	Diabetic Foot	2.6%
435	Staphylococcal Scalded Skin Syndrome	2.5%
436	Kearns-Sayre syndrome	2.5%
437	Peutz-Jeghers Syndrome	2.5%
438	carbuncle	2.4%
439	Giant Cell Arteritis	2.2%
440	Temporal Arteritis	2.2%
441	Condylomata Acuminata	2.2%
442	Furunculosis	2.2%
443	furuncle	2.2%
444	Impetigo	2.2%
445	Blastomycosis	2.1%
446	HIV-Associated Lipodystrophy Syndrome	2.1%
447	Familial Hypophosphatemic Rickets	2%
448	Rhinoscleroma	1.9%
449	Menkes Kinky Hair Syndrome	1.7%

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