MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Infarction, Middle Cerebral Artery

(UMLS:C0740392)

Definition:: NECROSIS occurring in the MIDDLE CEREBRAL ARTERY distribution system which brings blood to the entire lateral aspects of each CEREBRAL HEMISPHERE. Clinical signs include impaired cognition; APHASIA; AGRAPHIA; weak and numbness in the face and arms, contralaterally or bilaterally depending on the infarction.
UMLS ID:: C0740392
MeSH ID:: D020244

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.228.140.300.150.477.200.450|C10.228.140.300.510.200.387|C10.228.140.300.775.200.200.450

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.253.092.477.200.450|C14.907.253.560.200.387|C14.907.253.855.200.200.450

Synonym(s)

Infarction, Middle Cerebral Artery

mca infarction

middle cerebral artery infarct

middle cerebral artery stroke

stroke of middle cerebral artery

Associated Drug(s)

	Name	Reference(s)	Data Source
1	15-deoxyprostaglandin J2	16034372	CTD
2	3,5-di-tert-butyl-4-hydroxybenzoic acid	10027768	CTD
3	Amphetamine	17689416	CTD
4	Carvedilol	19371742	CTD
5	Cocaine	2388668	CTD
6	Estradiol	21277368	CTD
7	Fingolimod Hydrochloride	23043544	CTD
8	Halothane	17197033	CTD
9	Hydrogen Sulfide	31283913	CTD
10	Inositol	26079057	CTD
11	Lactic Acid	26079057	CTD
12	Lithium Chloride	26079057	CTD
13	Melatonin	18078455 18721861	CTD
14	Mifepristone	30229846	CTD
15	Minocycline	15862784 17942809	CTD
16	Misoprostol	18378387	CTD
17	Niacin	20451219	CTD
18	Nortriptyline	18174477	CTD
19	Oxygen	View details 23043544 23437309 26116440 27274199 31283913	CTD
20	Pioglitazone	17394460	CTD
21	Progesterone	15869954 21277368	CTD
22	Resveratrol	17600658 18572362	CTD
23	Rosiglitazone	View details 16034372 16539667 17394460 19321784	CTD
24	SB 239063	26116440	CTD
25	Sildenafil Citrate	18290852	CTD
26	Simvastatin	20451219	CTD
27	candesartan	16824557	CTD
28	gemcitabine	19427843	CTD
29	lipoxin A4	19321784	CTD
30	lithium succinate	26079057	CTD
31	notoginsenoside R1	24720662	CTD
32	phenyl-N-tert-butylnitrone	23199288	CTD
33	pifithrin	19475672	CTD
34	plumbagin	20028456	CTD
35	reviparin	10883918 11706099	CTD
36	sesamin	19835851	CTD
37	sodium bisulfide	31283913	CTD
38	tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex	22934841	CTD
39	ursolic acid	27274199	CTD
40	zileuton	19309543	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Infarction, Anterior Cerebral Artery	64.8%
2	Infarction, Posterior Cerebral Artery	64.8%
3	Moyamoya Disease	47.1%
4	Brain Stem Infarctions	45.6%
5	Basal Ganglia Cerebrovascular Disease	44.6%
6	Vascular Headaches	40.8%
7	Carotid Artery Diseases	40.4%
8	Vasospasm, Intracranial	40.4%
9	Leukomalacia, Periventricular	40.3%
10	Intracranial Embolism and Thrombosis	40.2%
11	Vasculitis, Central Nervous System	39.8%
12	Dementia, Vascular	39.5%
13	Intracranial Aneurysm	36.4%
14	Hypoxia-Ischemia, Brain	36.1%
15	Intracranial Arteriosclerosis	33.1%
16	Cerebral Atherosclerosis	33.1%
17	Cerebral Arteriosclerosis	33.1%
18	Carotid Artery Injuries	32.6%
19	Lateral Medullary Syndrome	31.1%
20	Vertebrobasilar Insufficiency	30.8%
21	Basilar Artery Stenosis	30.8%
22	Vertebral Artery Stenosis	30.8%
23	Transient Cerebral Ischemia	30.8%
24	Carotid Artery Thrombosis	29.6%
25	Cerebral Amyloid Angiopathy	29.6%
26	Basal Ganglia Hemorrhage	28.5%
27	Carotid Stenosis	27.9%
28	Brain Ischemia	27.4%
29	Cerebrovascular accident	27.4%
30	Intracranial Arterial Diseases	25.9%
31	Subarachnoid Hemorrhage, Traumatic	25.4%
32	Brain Infarction	25.3%
33	Meningoencephalitis	23.7%
34	Spinal Cord Vascular Diseases	23.5%
35	Pituitary Apoplexy	23%
36	Cerebral Thrombosis	23%
37	Intracranial Embolism	23%
38	Intracranial Thrombosis	23%
39	Encephalomyelitis	22.9%
40	Intracranial Hemorrhage, Hypertensive	22.9%
41	Subdural Effusion	22.3%
42	Vertebral Artery Dissection	22.2%
43	Lupus Vasculitis, Central Nervous System	22.2%
44	Giant Cell Arteritis	21.8%
45	Temporal Arteritis	21.8%
46	Carotid Artery, Internal, Dissection	21.5%
47	Myocardial Ischemia	21.1%
48	Pneumocephalus	21%
49	Brain Abscess	21%
50	Akinetic Mutism	20.6%
51	Anoxic Encephalopathy	20.6%
52	Basal Ganglia Diseases	20.6%
53	Brain Damage, Chronic	20.6%
54	Cerebellar Diseases	20.6%
55	Encephalitis	20.6%
56	Encephalomalacia	20.6%
57	Epilepsy	20.6%
58	Hydrocephalus	20.6%
59	Congenital Hydrocephalus	20.6%
60	Hypothalamic Diseases	20.6%
61	Thalamic Diseases	20.6%
62	Intracranial Hypertension	20.6%
63	Aura	20.6%
64	Leukoencephalopathy	20.6%
65	Neuroaxonal Dystrophies	20.6%
66	Headache Disorders	20.6%
67	Intracranial Hypotension	20.6%
68	Brain Edema	20.6%
69	Brain Hypoxia	20.6%
70	Aqueductal Stenosis	20.6%
71	Subarachnoid Hemorrhage	20.4%
72	Cerebral Hemorrhage	20.4%
73	Multiple System Atrophy	20.4%
74	Dandy-Walker Syndrome	19.8%
75	Subclavian Steal Syndrome	19%
76	Brain Injuries	18.5%
77	Ocular Motility Disorders	18.5%
78	Cyclophoria	18.5%
79	Putaminal Hemorrhage	18.5%
80	Brain Neoplasms	18.5%
81	Brain Diseases, Metabolic	18.3%
82	Dementia	18.3%
83	Lewy Body Disease	18%
84	Aneurysm	17.8%
85	Angiomatosis	17.8%
86	Aortic Diseases	17.8%
87	Arterial Occlusive Diseases	17.8%
88	Hyperemia	17.8%
89	Hypotension	17.8%
90	Superior Vena Cava Syndrome	17.8%
91	Telangiectasis	17.8%
92	Vasculitis	17.8%
93	Venous Insufficiency	17.8%
94	Peripheral Vascular Diseases	17.8%
95	Embolism and Thrombosis	17.8%
96	Angiodysplasia	17.8%
97	Capillary Leak Syndrome	17.8%
98	Prehypertension	17.8%
99	Parkinsonian Disorders	17.5%
100	Meningitis	17.2%
101	Movement Disorders	17.2%
102	Pachymeningitis	17.2%
103	Spinal Cord Diseases	17.2%
104	Thoracic Outlet Syndrome	17%
105	Aortic Aneurysm	16.8%
106	Aortitis	16.8%
107	Leriche Syndrome	16.8%
108	Periphlebitis	16.8%
109	Phlebitis	16.8%
110	Thromboangiitis Obliterans	16.8%
111	Retinal Vein Occlusion	16.7%
112	Hand-Arm Vibration Syndrome	16.7%
113	Epilepsy, Post-Traumatic	16.7%
114	Brain Hemorrhage, Traumatic	16.6%
115	Brain Death	16.6%
116	Optic Neuropathy, Ischemic	16.5%
117	Anterior Ischemic Optic Neuropathy	16.5%
118	Myocardial Reperfusion Injury	16.4%
119	Shy-Drager Syndrome	16.1%
120	Vascular System Injuries	16.1%
121	Cerebral Infarction	16%
122	Epidural Abscess	15.8%
123	Compartment syndromes	15.8%
124	Hepatic Veno-Occlusive Disease	15.8%
125	Peliosis Hepatis	15.8%
126	Varicocele	15.8%
127	Amblyopia	15.8%
128	MELAS Syndrome	15.7%
129	Diabetic Angiopathies	15.7%
130	Reperfusion Injury	15.7%
131	Splenic Infarction	15.7%
132	Vascular Neoplasms	15.7%
133	Vasoplegia	15.7%
134	Hemorrhoids	15.6%
135	Myelitis	15.6%
136	Central Nervous System Infection	15.5%
137	Infarction, Middle Cerebral Artery	15.2%
138	Huntington Disease	15.2%
139	Posterior Leukoencephalopathy Syndrome	15.2%
140	Posterior reversible encephalopathy syndrome	15.2%
141	Malignant Atrophic Papulosis	15%
142	Shwartzman Phenomenon	14.9%
143	Marchiafava-Bignami Disease	14.8%
144	Sinus Thrombosis, Intracranial	14.5%
145	Stiff-Person Syndrome	14.5%
146	Cerebral Arterial Diseases	14.3%
147	Progressive supranuclear palsy	14.2%
148	Mesenteric vascular insufficiency	14.1%
149	Angioedema	13.9%
150	Colitis, Ischemic	13.9%
151	Meige Syndrome	13.9%
152	Cerebral Ventriculitis	13.9%
153	Amnesia, Transient Global	13.8%
154	Arteriovenous fistula	13.3%
155	Dystonia Musculorum Deformans	13.3%
156	Neuroleptic Malignant Syndrome	13.2%
157	Myelinolysis, Central Pontine	13.2%
158	Parkinson Disease	13.2%
159	Subacute Combined Degeneration	13.2%
160	Postphlebitic Syndrome	13.1%
161	Coronary Aneurysm	13.1%
162	Prion Diseases	12.9%
163	Cerebellar Neoplasms	12.8%
164	Scimitar Syndrome	12.6%
165	Leukoencephalopathy, Progressive Multifocal	12.5%
166	Spinal Cord Ischemia	12.5%
167	Creutzfeldt-Jakob disease	12.4%
168	Hepatolenticular Degeneration	12.3%
169	Limbic Encephalitis	12.1%
170	Sturge-Weber Syndrome	12%
171	Spinal Cord Injuries	11.7%
172	Heart Diseases	11.7%
173	Spinal Muscular Atrophy	11.6%
174	Progressive Muscular Atrophy	11.6%
175	Aortic Rupture	11.6%
176	Asterixis	11.5%
177	Ballismus	11.5%
178	Cranial nerve diseases	11.4%
179	Demyelinating Diseases	11.4%
180	Demyelination	11.4%
181	Neuromuscular Diseases	11.4%
182	Chronobiology Disorders	11.4%
183	Amyotrophic Lateral Sclerosis	11.4%
184	Fabry Disease	11.3%
185	Coronary heart disease	11.2%
186	Myocardial Infarction	11.2%
187	Acute Coronary Syndrome	11.2%
188	Thrombophlebitis	11.1%
189	Cerebral Palsy	11.1%
190	Epilepsies, Partial	11.1%
191	Epilepsy, Generalized	11.1%
192	Pseudotumor Cerebri	11.1%
193	Hypertensive Encephalopathy	11.1%
194	Simple Partial Seizures	11.1%
195	Epilepsy, Reflex	11.1%
196	Headache Disorders, Primary	11.1%
197	Headache Disorders, Secondary	11.1%
198	Medication overuse headache	11.1%
199	Myoclonic Epilepsy	11%
200	Epilepsy, Temporal Lobe	11%
201	Epilepsy, Rolandic	11%
202	Benign Rolandic Epilepsy	11%
203	Presenile dementia	11%
204	Senile dementia	11%
205	Striatonigral Degeneration	11%
206	Ataxia Telangiectasia	10.9%
207	Poliomyelitis	10.8%
208	Meningitis, Bacterial	10.7%
209	Meningitis, Fungal	10.7%
210	Chronic Fatigue Syndrome	10.6%
211	Hematoma, Subdural	10.5%
212	Hematoma, Epidural, Cranial	10.5%
213	Blue Toe Syndrome	10.4%
214	Cavernous Sinus Thrombosis	10.3%
215	Sagittal Sinus Thrombosis	10.3%
216	Pregnancy Complications, Cardiovascular	10.3%
217	Cardiovascular Abnormalities	10.3%
218	Trauma, Nervous System	10.3%
219	Restless Legs Syndrome	10.3%
220	Ophthalmoplegic Migraine	10.1%
221	Motor Neuron Disease	10.1%
222	Nervous System Neoplasms	10.1%
223	Neurologic Manifestations	10.1%
224	Neurotoxicity Syndromes	10.1%
225	Toxoplasmosis, Cerebral	10.1%
226	Kounis Syndrome	10.1%
227	Pituitary Diseases	10%
228	May-Thurner Syndrome	9.9%
229	Angina Pectoris	9.9%
230	Paraneoplastic Cerebellar Degeneration	9.9%
231	Coronary Thrombosis	9.9%
232	Brain Injuries, Diffuse	9.9%
233	Traumatic Brain Injury	9.9%
234	Coronary Artery Disease	9.9%
235	Cerebellar Ataxia	9.9%
236	Supratentorial Neoplasms	9.9%
237	Miller Fisher Syndrome	9.8%
238	Leukoencephalitis, Acute Hemorrhagic	9.8%
239	Hypotension, Orthostatic	9.7%
240	Kluver-Bucy Syndrome	9.7%
241	Post-Exercise Hypotension	9.7%
242	Aneurysm, Dissecting	9.5%
243	Arteriosclerosis	9.5%
244	Arteritis	9.5%
245	Embolism	9.5%
246	Erythromelalgia	9.5%
247	Fibromuscular Dysplasia	9.5%
248	Malignant Hypertension	9.5%
249	Raynaud Disease	9.5%
250	Thromboembolism	9.5%
251	Thrombosis	9.5%
252	Essential Hypertension	9.5%
253	Aneurysm, Ruptured	9.5%
254	Iliac Aneurysm	9.5%
255	Pulmonary artery stenosis	9.5%
256	White Coat Hypertension	9.5%
257	Systemic Vasculitis	9.5%
258	Embolus	9.5%
259	Aortic Aneurysm, Abdominal	9.5%
260	Aortic Aneurysm, Thoracic	9.5%
261	Akathisia, Drug-Induced	9.5%
262	Myelitis, Transverse	9.3%
263	Persistent Vegetative State	9.3%
264	Polyradiculoneuropathy	9.3%
265	Polyradiculoneuritis	9.3%
266	Spinal Cord Neoplasms	9.2%
267	Sleep Wake Disorders	9.1%
268	Opsoclonus-Myoclonus Syndrome	9%
269	Embolism, Amniotic Fluid	8.9%
270	Arachnoiditis	8.8%
271	Aseptic Meningitis	8.8%
272	Syringomyelia	8.8%
273	Essential Tremor	8.8%
274	Familial Tremor	8.8%
275	Pneumorrhachis	8.8%
276	Writer's Cramp	8.8%
277	CREST Syndrome	8.8%
278	MPTP Poisoning	8.7%
279	Pituitary Adenoma	8.7%
280	Pituitary Neoplasms	8.7%
281	Reye Syndrome	8.7%
282	Hepatic Encephalopathy	8.7%
283	Encephalomyelitis, Acute Disseminated	8.6%
284	Polyarteritis Nodosa	8.5%
285	Takayasu Arteritis	8.5%
286	Retinal Artery Occlusion	8.5%
287	Retinal Vasculitis	8.5%
288	Hypertensive Retinopathy	8.5%
289	Anterior Compartment Syndrome	8.4%
290	Vasculitis, Leukocytoclastic, Cutaneous	8.4%
291	Gastric Antral Vascular Ectasia	8.4%
292	Abdominal Compartment Syndrome	8.4%
293	Varicose Ulcer	8.3%
294	Primary Graft Dysfunction	8.3%
295	Canavan Disease	8.2%
296	Alexander Disease	8.2%
297	Mitochondrial Encephalomyopathies	8.2%
298	Friedreich Ataxia	8.1%
299	Dyskinesia, Drug-Induced	8%
300	Brain Diseases, Metabolic, Inborn	7.9%
301	Central Nervous System Fungal Infections	7.8%
302	Conus Medullaris Syndrome	7.8%
303	Autonomic Dysreflexia	7.6%
304	Complex Regional Pain Syndromes	7.6%
305	Mesenteric Vascular Occlusion	7.5%
306	Mucocutaneous Lymph Node Syndrome	7.5%
307	Diabetic Retinopathy	7.5%
308	Livedo Reticularis	7.5%
309	Auditory Perceptual Disorders	7.5%
310	Renal hypertension	7.5%
311	Renal Artery Obstruction	7.5%
312	Renal Artery Stenosis	7.5%
313	Hemangioma, Cavernous	7.4%
314	Scurvy	7.4%
315	Hematoma, Subdural, Intracranial	7.2%
316	Hematoma, Subdural, Chronic	7.2%
317	Hematoma, Subdural, Acute	7.2%
318	Wernicke Encephalopathy	7.1%
319	AIDS Dementia Complex	7.1%
320	Anterior Spinal Artery Syndrome	7.1%
321	Central Nervous System Bacterial Infections	7.1%
322	Lambert-Eaton Myasthenic Syndrome	6.9%
323	Juvenile Myoclonic Epilepsy	6.9%
324	Myoclonic Epilepsies, Progressive	6.9%
325	Peripheral Nerve Injuries	6.9%
326	Myasthenia Gravis	6.8%
327	Ischemic contracture	6.8%
328	Angioedemas, Hereditary	6.7%
329	Tricuspid Atresia	6.7%
330	Arrhythmogenic Right Ventricular Dysplasia	6.7%
331	Cryoglobulinemia	6.7%
332	Diabetic Foot	6.7%
333	Kernicterus	6.6%
334	Adrenoleukodystrophy	6.6%
335	Bacterial Endocarditis	6.5%
336	Tuberculosis, Meningeal	6.5%
337	Coronary Occlusion	6.3%
338	Microvascular Angina	6.3%
339	Coronary Stenosis	6.3%
340	ST segment elevation myocardial infarction	6.3%
341	Post-Traumatic Headache	6.3%
342	Tension Headache	6.3%
343	Epilepsy, Complex Partial	6.3%
344	Migraine Disorders	6.3%
345	Abdominal Migraine	6.3%
346	Status Migrainosus	6.3%
347	Cervicogenic Headache	6.3%
348	Dural Arteriovenous Fistula	6.3%
349	Sleep Disorders, Circadian Rhythm	6.3%
350	Guillain-Barre Syndrome	6.3%
351	Botulism	6.1%
352	Central Nervous System Cysts	6.1%
353	Purpura, Hyperglobulinemic	6.1%
354	Scrapie	6.1%
355	Central Cord Syndrome	6.1%
356	Chorea	6%
357	Lafora Disease	6%
358	Unverricht-Lundborg Syndrome	6%
359	Cardiac Tamponade	5.9%
360	Endocarditis	5.9%
361	Cardiac Arrest	5.9%
362	Heart failure	5.9%
363	Pericardial effusion	5.9%
364	Pericarditis	5.9%
365	Pneumopericardium	5.9%
366	Cor pulmonale	5.9%
367	Ventricular Outflow Obstruction	5.9%
368	Ventricular Dysfunction	5.9%
369	Cardiomyopathies	5.9%
370	Pleuropericarditis	5.9%
371	Dysautonomia	5.7%
372	Vagus Nerve Disorder	5.7%
373	Glossopharyngeal Neuralgia	5.7%
374	Abducens Nerve Diseases	5.7%
375	Heavy Metal Poisoning, Nervous System	5.7%
376	Neuromuscular Junction Diseases	5.7%
377	Tauopathies	5.7%
378	Trochlear Nerve Diseases	5.7%
379	Peripheral Nervous System Diseases	5.7%
380	Shock, Cardiogenic	5.7%
381	Behcet Syndrome	5.7%
382	Waldenstrom Macroglobulinemia	5.6%
383	Multiple Myeloma	5.6%
384	Angina, Unstable	5.6%
385	Diffuse Axonal Injury	5.6%
386	Brain Stem Neoplasms	5.6%
387	Empty Sella Syndrome	5.6%
388	Hyperpituitarism	5.6%
389	Hypopituitarism	5.6%
390	Hypophysitis	5.6%
391	Aortic Valve Stenosis	5.6%
392	Cardiomyopathy, Dilated	5.6%
393	Pulmonary Valve Stenosis	5.6%
394	Frontotemporal dementia	5.5%
395	Lemierre Syndrome	5.4%
396	Arteriosclerosis Obliterans	5.4%
397	Atherosclerosis	5.4%
398	Air Embolism	5.4%
399	Endarteritis	5.4%
400	Venous Thrombosis	5.4%
401	Deep Vein Thrombosis	5.4%
402	Venous Thromboembolism	5.4%
403	Neuromyelitis Optica	5.4%
404	Olfactory Nerve Injuries	5.3%
405	Cardiac Output, High	5.3%
406	Myocardial Stunning	5.3%
407	Low Cardiac Output Syndrome	5.3%
408	Pseudoxanthoma Elasticum	5.3%
409	Meningitis, Cryptococcal	5.3%
410	Meningitis, Listeria	5.2%
411	Cardiomegaly	5.2%
412	Postpericardiotomy Syndrome	5.2%
413	Cardiac Hypertrophy	5.2%
414	Meningitis, Haemophilus	5.2%
415	Meningitis, Pneumococcal	5.2%
416	Rheumatic Heart Disease	5.2%
417	Progressive bulbar palsy	5.2%
418	Bulbar palsy	5.2%
419	Brain Concussion	5.2%
420	Myopathy	5.2%
421	Optic Neuropathy	5.2%
422	Subacute Sclerosing Panencephalitis	5.1%
423	Horner Syndrome	5.1%
424	Brain Contusion	5.1%
425	Facial Nerve Diseases	5.1%
426	Craniocerebral Trauma	5.1%
427	Parasomnia	5.1%
428	Dyssomnias	5.1%
429	Vestibulocochlear Nerve Diseases	5%
430	Decerebrate State	5%
431	Hemiparesis	5%
432	Hydranencephaly	5%
433	Meningism	5%
434	Neural Tube Defects	5%
435	Paresis	5%
436	Seizures	5%
437	Sensation Disorders	5%
438	Tethered Cord Syndrome	5%
439	Central Nervous System Neoplasms	5%
440	Complex partial seizures	5%
441	Iniencephaly	5%
442	Craniorachischisis	5%
443	Exencephaly	5%
444	Monoparesis	5%
445	Septo-Optic Dysplasia	5%
446	Cortical Dysplasia	5%
447	Neurogenic Inflammation	5%
448	Gait Disorders, Neurologic	5%
449	Neuromuscular Manifestations	5%
450	Malformations of Cortical Development	5%
451	Sweating, Gustatory	5%
452	Auriculotemporal Syndrome	5%
453	Heart Block	5%
454	Tachycardia	5%
455	Tachyarrhythmia	5%
456	Aortic coarctation	5%
457	Cor Triatriatum	5%
458	Coronary Vessel Anomalies	5%
459	Patent ductus arteriosus	5%
460	Ebstein Anomaly	5%
461	Heart Septal Defects	5%
462	Tetralogy of Fallot	5%
463	Transposition of Great Vessels	5%
464	Hypoplastic Left Heart Syndrome	5%
465	Tuberous Sclerosis	4.9%
466	Torticollis	4.9%
467	Refsum Disease	4.9%
468	Facial Nerve Injuries	4.8%
469	Intermittent Claudication	4.8%
470	Pulmonary Embolism	4.8%
471	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	4.8%
472	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	4.8%
473	Causalgia	4.8%
474	No-Reflow Phenomenon	4.8%
475	Jet Lag Syndrome	4.7%
476	Multiple Sclerosis	4.6%
477	Pupil Disorders	4.6%
478	Neurobehavioral Manifestations	4.6%
479	Paraneoplastic Encephalomyelitis	4.5%
480	Dextrocardia	4.5%
481	Long QT Syndrome	4.5%
482	Uveomeningoencephalitic Syndrome	4.5%
483	Vertigo	4.5%
484	Alcohol-Induced Disorders, Nervous System	4.5%
485	Myasthenia Gravis, Autoimmune, Experimental	4.4%
486	Hypertension, Renovascular	4.2%
487	Hereditary Angioedema Type III	4.2%
488	Hereditary Angioedema Types I and II	4.2%
489	Ophthalmoplegia	4.2%
490	External Ophthalmoplegia	4.2%
491	Alice in Wonderland Syndrome	4.2%
492	Tuberculosis, Central Nervous System	4.1%
493	Carcinoid Heart Disease	4.1%
494	Voice Disorders	4.1%
495	Voice Disturbance	4.1%
496	Smith-Magenis syndrome	4.1%
497	Reflex Sympathetic Dystrophy	4%
498	Nocturnal Myoclonus Syndrome	4%
499	Coronary Restenosis	3.9%
500	Cluster Headache	3.9%
501	Migraine with Aura	3.9%
502	Familial Hemiplegic Migraine	3.9%
503	Chronic Paroxysmal Hemicrania	3.9%
504	SUNCT Syndrome	3.9%
505	Paroxysmal Hemicrania	3.9%
506	Vocal Cord Paralysis	3.9%
507	Noonan Syndrome	3.8%
508	Hypertrophic Cardiomyopathy	3.8%
509	Hypertrophic obstructive cardiomyopathy	3.8%
510	Neuroaspergillosis	3.7%
511	Galactosemias	3.7%
512	Urea Cycle Disorders, Inborn	3.7%
513	Tyrosinemias	3.7%
514	Reflex, Abnormal	3.7%
515	Hyporeflexia	3.7%
516	Hyperreflexia	3.7%
517	Acrodynia	3.5%
518	Marfan Syndrome	3.5%
519	Angina Pectoris, Variant	3.5%
520	Choroid Plexus Papilloma	3.5%
521	Rheumatoid Vasculitis	3.5%
522	Charcot-Marie-Tooth Disease	3.5%
523	Alcohol Withdrawal Seizures	3.5%
524	Sick Sinus Syndrome	3.5%
525	Hyperprolactinemia	3.5%
526	Pseudorabies	3.5%
527	Homocystinuria	3.4%
528	Pick Disease of the Brain	3.4%
529	Leigh Disease	3.4%
530	Tardive Dyskinesia	3.3%
531	Neurosyphilis	3.3%
532	Myotonia Congenita	3.2%
533	Subacute Bacterial Endocarditis	3.2%
534	Menkes Kinky Hair Syndrome	3.2%
535	Cerebrospinal Fluid Otorrhea	3.2%
536	Cerebrospinal Fluid Rhinorrhea	3.2%
537	Neuritis, Autoimmune, Experimental	3.2%
538	Gait Ataxia	3.2%
539	Aortic Valve Insufficiency	3.2%
540	Restrictive cardiomyopathy	3.2%
541	Endocardial Fibroelastosis	3.2%
542	Heart Rupture, Post-Infarction	3.2%
543	Mitral Valve Insufficiency	3.2%
544	Mitral Valve Stenosis	3.2%
545	Myocarditis	3.2%
546	Pericarditis, Constrictive	3.2%
547	Pulmonary Valve Insufficiency	3.2%
548	Tricuspid Valve Insufficiency	3.2%
549	Tricuspid Valve Stenosis	3.2%
550	Ventricular Dysfunction, Left	3.2%
551	Right Ventricular Dysfunction	3.2%
552	Endomyocardial Fibrosis	3.2%
553	Carditis	3.2%
554	Heart Failure, Systolic	3.2%
555	Heart Failure, Diastolic	3.2%
556	Supravalvular aortic stenosis	3.2%
557	Lown-Ganong-Levine Syndrome	3.2%
558	West Nile Fever	3.1%
559	Acromegaly	3.1%
560	Lyme Neuroborreliosis	3%
561	Hepatic Vein Thrombosis	3%
562	Budd-Chiari Syndrome	3%
563	Pulmonary Infarction	3%
564	Myotonic Dystrophy	3%
565	Neuritis	2.9%
566	Polyneuritis	2.9%
567	Radiculitis	2.9%
568	Polyneuropathy	2.9%
569	Mononeuritis	2.9%
570	Mononeuropathies	2.9%
571	Brachial Plexus Neuropathies	2.9%
572	Radiculopathy	2.9%
573	Mononeuropathy Multiplex	2.9%
574	Nerve Root Compression	2.9%
575	Akathisia	2.9%
576	Restlessness	2.9%
577	Psychomotor Agitation	2.9%
578	Zellweger Syndrome	2.8%
579	Adams-Stokes Syndrome	2.8%
580	Atrioventricular Block	2.8%
581	Bundle-Branch Block	2.8%
582	Atrial Premature Complexes	2.8%
583	Sinoatrial Block	2.8%
584	Tachycardia, Paroxysmal	2.8%
585	Supraventricular tachycardia	2.8%
586	Tachycardia, Ventricular	2.8%
587	Wolff-Parkinson-White Syndrome	2.8%
588	Tachycardia, Reciprocating	2.8%
589	Aortopulmonary Septal Defect	2.8%
590	Double Outlet Right Ventricle	2.8%
591	Endocardial Cushion Defects	2.8%
592	Myocardial bridging	2.8%
593	Aorticopulmonary Septal Defect	2.8%
594	Sinus Arrhythmia	2.8%
595	Atrial Fibrillation	2.8%
596	Atrial Flutter	2.8%
597	Edema, Cardiac	2.8%
598	Ventricular Fibrillation	2.8%
599	Ventricular Flutter	2.8%
600	Parasystole	2.8%
601	Paroxysmal atrial fibrillation	2.8%
602	Bradycardia	2.8%
603	Diabetic Cardiomyopathies	2.8%
604	Cardiomyopathy, Alcoholic	2.8%
605	Ectopia Cordis	2.8%
606	Sudden Cardiac Death	2.8%
607	Left Ventricular Hypertrophy	2.8%
608	Right Ventricular Hypertrophy	2.8%
609	Single umbilical artery	2.8%
610	Acoustic Neuroma	2.8%
611	Chagas Cardiomyopathy	2.8%
612	Brachial Plexus Neuritis	2.8%
613	Neuralgic Amyotrophy	2.8%
614	Coma, Post-Head Injury	2.7%
615	Granulomatosis with polyangiitis	2.7%
616	Myositis	2.6%
617	Optic Atrophy	2.6%
618	Optic Neuritis	2.6%
619	Papilledema	2.6%
620	Strabismus	2.6%
621	Tolosa-Hunt Syndrome	2.6%
622	Isaacs syndrome	2.6%
623	Arsenic Poisoning	2.6%
624	Myotonic Disorders	2.6%
625	Myasthenic Syndromes, Congenital	2.6%
626	Diabetic Neuropathies	2.6%
627	Facial Injuries	2.6%
628	Facial Neuralgia	2.6%
629	Diabetic Amyotrophy	2.6%
630	Diabetic Autonomic Neuropathy	2.6%
631	Sleep Talking	2.6%
632	Manganese Poisoning	2.6%
633	Sleep Disorders, Intrinsic	2.6%
634	Orthostatic intolerance	2.6%
635	Kearns-Sayre syndrome	2.6%
636	Anosmia	2.6%
637	Ataxia	2.6%
638	Athetosis	2.6%
639	Catalepsy	2.6%
640	Dystonia	2.6%
641	Hemiplegia	2.6%
642	Locked-In Syndrome	2.6%
643	Meningeal Neoplasms	2.6%
644	Meningomyelocele	2.6%
645	Muscle Hypertonia	2.6%
646	Muscle hypotonia	2.6%
647	Myoclonus	2.6%
648	Myotonia	2.6%
649	Neuralgia	2.6%
650	Paraplegia	2.6%
651	Pseudobulbar Palsy	2.6%
652	Quadriplegia	2.6%
653	Spasm	2.6%
654	Spastic Paraplegia	2.6%
655	Status Epilepticus	2.6%
656	Taste Disorders	2.6%
657	Tremor	2.6%
658	Spina Bifida	2.6%
659	Monoplegia	2.6%
660	Hypokinesia	2.6%
661	Paraparesis	2.6%
662	Bradykinesia	2.6%
663	Waxy flexibility	2.6%
664	Action Tremor	2.6%
665	Resting Tremor	2.6%
666	Dysosmia	2.6%
667	Quadriparesis	2.6%
668	Mercury Poisoning, Nervous System	2.6%
669	Olfaction Disorders	2.6%
670	Myokymia	2.6%
671	Lead Poisoning, Nervous System	2.6%
672	Vestibular Neuronitis	2.6%
673	Somatosensory Disorders	2.6%
674	Neuropathic pain	2.6%
675	Hyperkinesia	2.6%
676	Intention tremor	2.6%
677	Alstrom Syndrome	2.6%
678	Prolactinoma	2.5%
679	Growth Hormone-Secreting Pituitary Adenoma	2.5%
680	Romano-Ward Syndrome	2.5%
681	Dyspnea, Paroxysmal	2.5%
682	Optic Nerve Glioma	2.5%
683	Multiple Sclerosis, Chronic Progressive	2.5%
684	Multiple Sclerosis, Relapsing-Remitting	2.5%
685	Amyloid Neuropathies, Familial	2.5%
686	Gait Apraxia	2.5%
687	Vision Disorders	2.4%
688	Metamorphopsia	2.4%
689	Visual Impairment	2.4%
690	Turner Syndrome	2.4%
691	Fibromyalgia	2.4%
692	Medial Tibial Stress Syndrome	2.4%
693	Facial Hemiatrophy	2.3%
694	Melkersson-Rosenthal Syndrome	2.3%
695	Mitochondrial Myopathies	2.3%
696	Anisocoria	2.3%
697	Confusion	2.3%
698	Facial paralysis	2.3%
699	Lethargy	2.3%
700	Memory Disorders	2.3%
701	Muscle Cramp	2.3%
702	Perceptual Disorders	2.3%
703	Psychomotor Disorders	2.3%
704	Tonic Pupil	2.3%
705	Eosinophilia-Myalgia Syndrome	2.3%
706	Anhedonia	2.3%
707	Disorientation	2.3%
708	Facial Paresis	2.3%
709	Memory Loss	2.3%
710	Hemisensory Neglect	2.3%
711	Dysacusis	2.3%
712	Sleep Bruxism	2.3%
713	Anencephaly	2.3%
714	Meningocele	2.3%
715	Muscular Atrophy	2.3%
716	Respiratory Paralysis	2.3%
717	Encephalocele	2.3%
718	Tetany	2.3%
719	Tarsal Tunnel Syndrome	2.2%
720	Cauda Equina Syndrome	2.2%
721	Carbamoyl-Phosphate Synthase I Deficiency Disease	2.1%
722	Toxoplasmosis, Congenital	2.1%
723	Malaria, Cerebral	2.1%
724	Duane Retraction Syndrome	2.1%
725	Neurocysticercosis	2.1%
726	Consciousness Disorders	2.1%
727	Mental Retardation	2.1%
728	Muscle Weakness	2.1%
729	Depressed Level of Consciousness	2.1%
730	Mental deficiency	2.1%
731	Intellectual Disability	2.1%
732	Mobius Syndrome	2.1%
733	Bell Palsy	2.1%
734	Catatonia	2.1%
735	Herpes Zoster Oticus	2.1%
736	Familial Periodic Paralysis	2.1%
737	Aphonia	2.1%
738	Sleep Deprivation	2.1%
739	Dysphonia	2.1%
740	Waterhouse-Friderichsen Syndrome	2.1%
741	Glycogen storage disease type II	2%
742	Carpal Tunnel Syndrome	1.9%
743	Nelson Syndrome	1.9%
744	neurofibroma	1.9%
745	Sciatica	1.9%
746	Williams Syndrome	1.9%
747	Myalgia	1.9%
748	Neuronal Ceroid-Lipofuscinoses	1.9%
749	Aortic Valve Prolapse	1.8%
750	Tricuspid Valve Prolapse	1.8%
751	Takotsubo Cardiomyopathy	1.8%
752	Aicardi's syndrome	1.8%
753	Hoarseness	1.8%
754	Tachycardia, Atrioventricular Nodal Reentry	1.8%
755	Tachycardia, Ectopic Atrial	1.8%
756	Tachycardia, Ectopic Junctional	1.8%
757	Sinus Tachycardia	1.8%
758	Torsades de Pointes	1.8%
759	Accelerated Idioventricular Rhythm	1.8%
760	Truncus Arteriosus, Persistent	1.8%
761	Cockayne Syndrome	1.7%
762	Alcohol Withdrawal Delirium	1.7%
763	Holoprosencephaly	1.6%
764	Sinus Arrest, Cardiac	1.6%
765	Classical Lissencephalies and Subcortical Band Heterotopias	1.6%
766	Sciatic Neuropathy	1.6%
767	Ulnar Neuropathies	1.6%
768	Lesion of Sciatic Nerve	1.6%
769	Ulnar Neuritis	1.6%
770	Radial nerve compression	1.6%
771	Radial Tunnel Syndrome	1.6%
772	Peroneal Neuropathies	1.6%
773	Radial Neuropathy	1.6%
774	Median Neuropathy	1.6%
775	Sciatic Nerve Palsy	1.6%
776	Femoral Neuropathy	1.6%
777	Tibial Neuropathy	1.6%
778	Ulnar Nerve Palsy	1.6%
779	Postural Orthostatic Tachycardia Syndrome	1.6%
780	Radial nerve palsy	1.6%
781	Kartagener Syndrome	1.5%
782	Cubital Tunnel Syndrome	1.4%
783	Esotropia	1.4%
784	Exotropia	1.4%
785	Sleep Apnea Syndromes	1.4%
786	Polymyositis	1.4%
787	Disorders of Excessive Somnolence	1.4%
788	Sleep Initiation and Maintenance Disorders	1.4%
789	Night Terrors	1.4%
790	Somnambulism	1.4%
791	Trigeminal Nerve Disorder	1.4%
792	Transient Insomnia	1.4%
793	Sleep Paralysis	1.4%
794	Chronic Insomnia	1.4%
795	REM Sleep Behavior Disorder	1.4%
796	Hypersomnia	1.4%
797	Dermal Sinus	1.4%
798	Dysgeusia	1.4%
799	Formication	1.4%
800	Hyperalgesia	1.4%
801	Hyperesthesia	1.4%
802	Hypesthesia	1.4%
803	Language Disorders	1.4%
804	Numbness	1.4%
805	Paresthesia	1.4%
806	Paraparesis, Spastic	1.4%
807	Spina Bifida Cystica	1.4%
808	Trismus	1.4%
809	Spina Bifida Occulta	1.4%
810	Epilepsia Partialis Continua	1.4%
811	Hypogeusia	1.4%
812	Meningeal Carcinomatosis	1.4%
813	Brown-Sequard Syndrome	1.4%
814	Lissencephaly	1.4%
815	Polymicrogyria	1.4%
816	Pachygyria	1.4%
817	Schizencephaly	1.4%
818	Lockjaw	1.4%
819	Allodynia	1.4%
820	Lead Poisoning, Nervous System, Childhood	1.4%
821	Lead Poisoning, Nervous System, Adult	1.4%
822	Periventricular Nodular Heterotopia	1.4%
823	Ageusia	1.4%
824	Optic Atrophy, Hereditary, Leber	1.4%
825	Gaucher Disease	1.3%
826	Eye Injuries	1.3%
827	Muscular Dystrophy	1.3%
828	Congenital nystagmus	1.3%
829	Orbital Myositis	1.3%
830	Diplopia	1.2%
831	Muscle Rigidity	1.2%
832	Muscle Spasticity	1.2%
833	Scotoma	1.2%
834	Photophobia	1.2%
835	Cogwheel Rigidity	1.2%
836	Hemifacial Spasm	1.2%
837	Amaurosis	1.2%
838	Blindness	1.2%
839	Nuchal Rigidity	1.2%
840	Pyomyositis	1.2%
841	Agnosia	1.2%
842	Apraxias	1.2%
843	Hallucinations	1.2%
844	Hemianopsia	1.2%
845	Hyperacusis	1.2%
846	Tinnitus	1.2%
847	Visual Agnosia	1.2%
848	Anosognosia	1.2%
849	Wernicke-Korsakoff Syndrome	1.2%
850	Phonophobia	1.2%
851	Hearing Loss	1.2%
852	Sarcopenia	1.2%
853	Alexia	1.2%
854	Dyslexia	1.2%
855	Amnesia	1.1%
856	Delirium	1.1%
857	Dissociative Amnesia	1.1%
858	Color blindness	1.1%
859	Global Amnesia	1.1%
860	Cri-du-Chat Syndrome	1.1%
861	Down Syndrome	1.1%
862	Trisomy 21	1.1%
863	POEMS Syndrome	1.1%
864	Meningioma	1.1%
865	Microcephaly	1.1%
866	Macrocephaly	1.1%
867	Hypokalemic periodic paralysis	1.1%
868	Porencephaly	1.1%
869	Prader-Willi Syndrome	1%
870	Phantom pain	1%
871	Phantom Limb Pain	1%
872	Niemann-Pick Disease, Type C	0.9%
873	Neurofibrosarcoma	0.9%
874	Polyradiculopathy	0.9%
875	Tay-Sachs Disease	0.9%
876	Rubinstein-Taybi Syndrome	0.9%
877	Sleep Apnea, Obstructive	0.8%
878	Sleep Apnea, Central	0.8%
879	Narcolepsy	0.8%
880	Trigeminal Neuralgia	0.8%
881	Kleine-Levin Syndrome	0.8%
882	Agraphia	0.8%
883	Anomia	0.8%
884	Cluttering	0.8%
885	Language Development Disorders	0.8%
886	Speech Disorders	0.8%
887	Syncope	0.8%
888	Stupor	0.8%
889	Dysgraphia	0.8%
890	Presyncope	0.8%
891	Dyslalia	0.8%
892	Eye Burns	0.7%
893	Welander Distal Myopathy	0.7%
894	Amaurosis Fugax	0.7%
895	Blindness, Cortical	0.7%
896	Dyscalculia	0.7%
897	Rett Syndrome	0.7%
898	Deafness	0.7%
899	Hearing Loss, Sudden	0.7%
900	Gerstmann Syndrome	0.7%
901	Hearing Loss, Bilateral	0.7%
902	Hearing Loss, High-Frequency	0.7%
903	Hearing Loss, Mixed Conductive-Sensorineural	0.7%
904	Prosopagnosia	0.7%
905	Apraxia, Ideomotor	0.7%
906	Charles Bonnet Syndrome	0.7%
907	Hearing Loss, Unilateral	0.7%
908	Complete Hearing Loss	0.7%
909	Alien Hand Syndrome	0.7%
910	Deaf Mutism	0.7%
911	Dermatomyositis	0.6%
912	Corneal Scar	0.6%
913	Muscular Dystrophy, Duchenne	0.6%
914	Retrograde amnesia	0.6%
915	Amnesia, Anterograde	0.6%
916	Fragile X Syndrome	0.6%
917	Cataplexy	0.5%
918	Aphasia	0.5%
919	Articulation Disorders	0.5%
920	Echolalia	0.5%
921	Stuttering	0.5%
922	Dysphasia	0.5%
923	Mucopolysaccharidosis II	0.5%
924	Mutism	0.4%
925	Selective Mutism	0.4%
926	Corneal Perforation	0.4%
927	Dysarthria	0.3%
928	Alexia, Pure	0.3%

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