MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Chagas Cardiomyopathy

(UMLS:C0007930)

Definition:: A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
UMLS ID:: C0007930
MeSH ID:: D002598

Classification 1:

Name:

Parasitic Diseases
MeSH Tree Number(s):: C03.752.300.900.200.190

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.238.190

Synonym(s)

Chagas Cardiomyopathy

Cardiomyopathy in Chagas' Disease

Cardiovascular Trypanosomiasis

Chagas' cardiomyopathy

Chagas' disease cardiomyopathy

Chagas' disease with heart involvement

Chagas; acute, cardiovascular (etiology)

Chagas; cardiovascular involvement (etiology)

Chagas; cardiovascular involvement (manifestation)

10.

Chronic Chagas' Disease Cardiomyopathy

11.

trypanosomiasis involving the heart

12.

trypanosomiasis with cardiac involvement

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Digoxin		16764726	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Cardiomyopathy, Dilated	32.9%
2	Restrictive cardiomyopathy	30.6%
3	Endocardial Fibroelastosis	30.6%
4	Myocarditis	30.6%
5	Endomyocardial Fibrosis	30.6%
6	Carditis	30.6%
7	Hypertrophic Cardiomyopathy	28.9%
8	Hypertrophic obstructive cardiomyopathy	28.9%
9	African Trypanosomiasis	24.3%
10	Arrhythmogenic Right Ventricular Dysplasia	24.1%
11	Diabetic Cardiomyopathies	23%
12	Cardiomyopathy, Alcoholic	22.9%
13	Myocardial Reperfusion Injury	22.6%
14	Myocardial Ischemia	20.4%
15	Cardiac Tamponade	20.1%
16	Endocarditis	20.1%
17	Cardiac Arrest	20.1%
18	Heart failure	20.1%
19	Pericardial effusion	20.1%
20	Pericarditis	20.1%
21	Pneumopericardium	20.1%
22	Cor pulmonale	20.1%
23	Ventricular Outflow Obstruction	20.1%
24	Ventricular Dysfunction	20.1%
25	Pleuropericarditis	20.1%
26	Aortic Valve Stenosis	19.8%
27	Pulmonary Valve Stenosis	19.8%
28	Heart Block	15.8%
29	Tachycardia	15.8%
30	Tachyarrhythmia	15.8%
31	Tricuspid Atresia	15.3%
32	Cardiac Output, High	15.3%
33	Myocardial Stunning	15.3%
34	Low Cardiac Output Syndrome	15.3%
35	Amebiasis	15.1%
36	Coccidiosis	15.1%
37	Malaria	15.1%
38	Acanthamoeba Infection	15.1%
39	Trichomonas Infections	15.1%
40	Ciliophora Infections	15.1%
41	Balamuthia Infection	15.1%
42	Cardiomegaly	15.1%
43	Postpericardiotomy Syndrome	15.1%
44	Cardiac Hypertrophy	15.1%
45	Rheumatic Heart Disease	14.9%
46	Leishmaniasis	14.6%
47	Supravalvular aortic stenosis	14.6%
48	Lown-Ganong-Levine Syndrome	14.6%
49	Coronary heart disease	13.2%
50	Myocardial Infarction	13.2%
51	Acute Coronary Syndrome	13.2%
52	Long QT Syndrome	13.2%
53	Aortic Valve Insufficiency	13.1%
54	Heart Rupture, Post-Infarction	13.1%
55	Mitral Valve Insufficiency	13.1%
56	Mitral Valve Stenosis	13.1%
57	Pericarditis, Constrictive	13.1%
58	Pulmonary Valve Insufficiency	13.1%
59	Tricuspid Valve Insufficiency	13.1%
60	Tricuspid Valve Stenosis	13.1%
61	Ventricular Dysfunction, Left	13.1%
62	Right Ventricular Dysfunction	13.1%
63	Heart Failure, Systolic	13.1%
64	Heart Failure, Diastolic	13.1%
65	Sick Sinus Syndrome	12.5%
66	Protozoan Infections, Animal	12.4%
67	Giardiasis	12.1%
68	Vascular Diseases	11.7%
69	Adams-Stokes Syndrome	11.7%
70	Atrioventricular Block	11.7%
71	Bundle-Branch Block	11.7%
72	Atrial Premature Complexes	11.7%
73	Sinoatrial Block	11.7%
74	Tachycardia, Paroxysmal	11.7%
75	Supraventricular tachycardia	11.7%
76	Tachycardia, Ventricular	11.7%
77	Wolff-Parkinson-White Syndrome	11.7%
78	Tachycardia, Reciprocating	11.7%
79	Leishmaniasis, Visceral	11.4%
80	Kounis Syndrome	10.7%
81	Aortic coarctation	10.5%
82	Cor Triatriatum	10.5%
83	Coronary Vessel Anomalies	10.5%
84	Patent ductus arteriosus	10.5%
85	Ebstein Anomaly	10.5%
86	Heart Septal Defects	10.5%
87	Tetralogy of Fallot	10.5%
88	Transposition of Great Vessels	10.5%
89	Hypoplastic Left Heart Syndrome	10.5%
90	Angina Pectoris	10.5%
91	Coronary Aneurysm	10.4%
92	Bacterial Endocarditis	10.1%
93	Helminthiasis	9.9%
94	Sinus Arrhythmia	9.9%
95	Atrial Fibrillation	9.9%
96	Atrial Flutter	9.9%
97	Edema, Cardiac	9.9%
98	Ventricular Fibrillation	9.9%
99	Ventricular Flutter	9.9%
100	Parasystole	9.9%
101	Paroxysmal atrial fibrillation	9.9%
102	Bradycardia	9.9%
103	Sudden Cardiac Death	9.8%
104	Left Ventricular Hypertrophy	9.8%
105	Right Ventricular Hypertrophy	9.8%
106	Aortic Valve Prolapse	9.7%
107	Tricuspid Valve Prolapse	9.7%
108	Takotsubo Cardiomyopathy	9.7%
109	Carcinoid Heart Disease	9.7%
110	Coronary Occlusion	9.7%
111	Microvascular Angina	9.7%
112	Coronary Stenosis	9.7%
113	ST segment elevation myocardial infarction	9.7%
114	Coronary Thrombosis	9.7%
115	Coronary Artery Disease	9.7%
116	Romano-Ward Syndrome	9.7%
117	Babesiosis	9.6%
118	Tachycardia, Atrioventricular Nodal Reentry	9.6%
119	Tachycardia, Ectopic Atrial	9.6%
120	Tachycardia, Ectopic Junctional	9.6%
121	Sinus Tachycardia	9.6%
122	Torsades de Pointes	9.6%
123	Accelerated Idioventricular Rhythm	9.6%
124	Cryptosporidiosis	9.1%
125	Pregnancy Complications, Cardiovascular	8.8%
126	Cardiovascular Abnormalities	8.8%
127	Dextrocardia	8.8%
128	Leishmaniasis, Cutaneous	8.4%
129	Entamoebiasis	8.2%
130	Malaria, Falciparum	8.2%
131	Malaria, Vivax	8.2%
132	Toxoplasmosis	8.2%
133	Isosporiasis	8.2%
134	Coronary Restenosis	8%
135	Dyspnea, Paroxysmal	7.9%
136	Shock, Cardiogenic	7.8%
137	Parasitic Diseases, Animal	7.8%
138	Aortopulmonary Septal Defect	7.7%
139	Double Outlet Right Ventricle	7.7%
140	Endocardial Cushion Defects	7.7%
141	Myocardial bridging	7.7%
142	Aorticopulmonary Septal Defect	7.7%
143	Angina, Unstable	7.7%
144	Kearns-Sayre syndrome	7.5%
145	Liver Diseases, Parasitic	7.5%
146	Intestinal Diseases, Parasitic	7.4%
147	Pregnancy Complications, Parasitic	7.4%
148	Sinus Arrest, Cardiac	7.3%
149	Parasitemia	7.3%
150	Aneurysm	6.7%
151	Angiomatosis	6.7%
152	Aortic Diseases	6.7%
153	Arterial Occlusive Diseases	6.7%
154	Hyperemia	6.7%
155	Hypotension	6.7%
156	Superior Vena Cava Syndrome	6.7%
157	Telangiectasis	6.7%
158	Vasculitis	6.7%
159	Venous Insufficiency	6.7%
160	Peripheral Vascular Diseases	6.7%
161	Embolism and Thrombosis	6.7%
162	Angiodysplasia	6.7%
163	Capillary Leak Syndrome	6.7%
164	Prehypertension	6.7%
165	Acanthamoeba Keratitis	6.7%
166	Noonan Syndrome	6.6%
167	Aortic Aneurysm	6.6%
168	Aortitis	6.6%
169	Leriche Syndrome	6.6%
170	Periphlebitis	6.6%
171	Phlebitis	6.6%
172	Thromboangiitis Obliterans	6.6%
173	Malaria, Cerebral	6.5%
174	Truncus Arteriosus, Persistent	6.4%
175	Angina Pectoris, Variant	6.4%
176	Helminthiasis, Animal	6.2%
177	Opportunistic Infections	6.2%
178	Trichomonas Vaginitis	6.1%
179	Subacute Bacterial Endocarditis	6.1%
180	Embolism, Amniotic Fluid	6%
181	Marfan Syndrome	6%
182	Postphlebitic Syndrome	5.7%
183	Retinal Vein Occlusion	5.7%
184	Arteriovenous fistula	5.7%
185	Liver Abscess, Amebic	5.7%
186	Thrombophlebitis	5.5%
187	Vascular System Injuries	5.3%
188	Malignant Atrophic Papulosis	5.3%
189	Shwartzman Phenomenon	5.2%
190	May-Thurner Syndrome	5.2%
191	Compartment syndromes	5.1%
192	Hepatic Veno-Occlusive Disease	5.1%
193	Peliosis Hepatis	5.1%
194	Varicocele	5.1%
195	Blue Toe Syndrome	5.1%
196	Cestode Infections	5%
197	Nematode infections	5%
198	Trematode Infections	5%
199	Cerebrovascular Disorders	5%
200	Diabetic Angiopathies	5%
201	Reperfusion Injury	5%
202	Splenic Infarction	5%
203	Cerebrovascular Insufficiency	5%
204	Vascular Neoplasms	5%
205	Spinal Cord Vascular Diseases	5%
206	Vasoplegia	5%
207	Hemorrhoids	5%
208	Thoracic Outlet Syndrome	5%
209	Aortic Rupture	4.9%
210	Blackwater Fever	4.9%
211	Aortic Aneurysm, Abdominal	4.9%
212	Aortic Aneurysm, Thoracic	4.9%
213	Fascioliasis	4.7%
214	Larva Migrans	4.7%
215	Intracranial Embolism and Thrombosis	4.6%
216	Carotid Artery Thrombosis	4.6%
217	Carotid Stenosis	4.5%
218	Intracranial Aneurysm	4.5%
219	Moyamoya Disease	4.4%
220	Aneurysm, Dissecting	4.4%
221	Arteriosclerosis	4.4%
222	Arteritis	4.4%
223	Embolism	4.4%
224	Erythromelalgia	4.4%
225	Fibromuscular Dysplasia	4.4%
226	Malignant Hypertension	4.4%
227	Raynaud Disease	4.4%
228	Thromboembolism	4.4%
229	Thrombosis	4.4%
230	Essential Hypertension	4.4%
231	Aneurysm, Ruptured	4.4%
232	Iliac Aneurysm	4.4%
233	Pulmonary artery stenosis	4.4%
234	White Coat Hypertension	4.4%
235	Systemic Vasculitis	4.4%
236	Embolus	4.4%
237	Scimitar Syndrome	4.2%
238	Hand-Arm Vibration Syndrome	4.2%
239	Williams Syndrome	4.1%
240	Optic Neuropathy, Ischemic	4.1%
241	Anterior Ischemic Optic Neuropathy	4.1%
242	Mesenteric vascular insufficiency	4.1%
243	Echinococcosis, Hepatic	4%
244	Angioedema	4%
245	Colitis, Ischemic	3.9%
246	Polyarteritis Nodosa	3.9%
247	Takayasu Arteritis	3.9%
248	Intracranial Arteriosclerosis	3.9%
249	Cerebral Atherosclerosis	3.9%
250	Cerebral Arteriosclerosis	3.9%
251	Vasculitis, Central Nervous System	3.8%
252	Cerebral Thrombosis	3.5%
253	Intracranial Embolism	3.5%
254	Intracranial Thrombosis	3.5%
255	Onchocerciasis	3.4%
256	Turner Syndrome	3.4%
257	Retinal Artery Occlusion	3.3%
258	Retinal Vasculitis	3.3%
259	Hypertensive Retinopathy	3.3%
260	Anterior Compartment Syndrome	3.3%
261	Vasculitis, Leukocytoclastic, Cutaneous	3.3%
262	Gastric Antral Vascular Ectasia	3.3%
263	Abdominal Compartment Syndrome	3.3%
264	Toxocariasis	3.3%
265	Carotid Artery Diseases	3.3%
266	Brain Ischemia	3.3%
267	Ectopia Cordis	3.3%
268	Hypotension, Orthostatic	3.3%
269	Cerebrovascular accident	3.3%
270	Varicose Ulcer	3.3%
271	Vasospasm, Intracranial	3.3%
272	Spinal Cord Ischemia	3.3%
273	Intracranial Arterial Diseases	3.3%
274	Primary Graft Dysfunction	3.3%
275	Single umbilical artery	3.3%
276	Post-Exercise Hypotension	3.3%
277	Giant Cell Arteritis	3.2%
278	Temporal Arteritis	3.2%
279	Arteriosclerosis Obliterans	3.2%
280	Atherosclerosis	3.2%
281	Air Embolism	3.2%
282	Endarteritis	3.2%
283	Venous Thrombosis	3.2%
284	Deep Vein Thrombosis	3.2%
285	Venous Thromboembolism	3.2%
286	Brain Infarction	3.2%
287	Dirofilariasis	3.1%
288	Superinfection	3.1%
289	Sinus Thrombosis, Intracranial	3%
290	Lemierre Syndrome	3%
291	Toxoplasmosis, Congenital	3%
292	Kartagener Syndrome	2.9%
293	Subarachnoid Hemorrhage, Traumatic	2.8%
294	Carotid Artery, Internal, Dissection	2.8%
295	Strongyle Infections, Equine	2.8%
296	CREST Syndrome	2.8%
297	Vertebral Artery Dissection	2.8%
298	Cavernous Sinus Thrombosis	2.8%
299	Sagittal Sinus Thrombosis	2.8%
300	Infarction, Middle Cerebral Artery	2.8%
301	Infarction, Anterior Cerebral Artery	2.8%
302	Infarction, Posterior Cerebral Artery	2.8%
303	Diphyllobothriasis	2.7%
304	Echinococcosis	2.7%
305	Hymenolepiasis	2.7%
306	Mite Infestations	2.7%
307	Myiasis	2.7%
308	Opisthorchiasis	2.7%
309	Schistosomiasis	2.7%
310	Tick Infestations	2.7%
311	Secernentea Infections	2.7%
312	Mesenteric Vascular Occlusion	2.7%
313	Mucocutaneous Lymph Node Syndrome	2.7%
314	Cerebral Infarction	2.7%
315	Brain Stem Infarctions	2.7%
316	Diabetic Retinopathy	2.7%
317	Sturge-Weber Syndrome	2.7%
318	Livedo Reticularis	2.6%
319	Renal hypertension	2.6%
320	Renal Artery Obstruction	2.6%
321	Renal Artery Stenosis	2.6%
322	Hemangioma, Cavernous	2.6%
323	Basal Ganglia Cerebrovascular Disease	2.6%
324	Vascular Headaches	2.6%
325	Scurvy	2.6%
326	Toxoplasmosis, Cerebral	2.5%
327	Intermittent Claudication	2.5%
328	Pulmonary Embolism	2.5%
329	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.5%
330	No-Reflow Phenomenon	2.4%
331	Carotid Artery Injuries	2.4%
332	Cerebral Arterial Diseases	2.4%
333	Vertebrobasilar Insufficiency	2.4%
334	Anterior Spinal Artery Syndrome	2.4%
335	Basilar Artery Stenosis	2.4%
336	Vertebral Artery Stenosis	2.4%
337	Intracranial Hemorrhage, Hypertensive	2.4%
338	Transient Cerebral Ischemia	2.4%
339	Lateral Medullary Syndrome	2.4%
340	Neurocysticercosis	2.3%
341	Dural Arteriovenous Fistula	2.2%
342	Ischemic contracture	2.2%
343	Basal Ganglia Hemorrhage	2.2%
344	Angioedemas, Hereditary	2.2%
345	Cryoglobulinemia	2.2%
346	Leukomalacia, Periventricular	2.2%
347	Diabetic Foot	2.2%
348	AIDS-Related Opportunistic Infections	2.2%
349	Hepatic Vein Thrombosis	2.1%
350	Budd-Chiari Syndrome	2.1%
351	Lice Infestations	2%
352	Pulmonary Infarction	2%
353	Subclavian Steal Syndrome	2%
354	Hypertension, Renovascular	1.9%
355	Subarachnoid Hemorrhage	1.9%
356	Hypoxia-Ischemia, Brain	1.9%
357	Cerebral Hemorrhage	1.9%
358	Hereditary Angioedema Type III	1.9%
359	Hereditary Angioedema Types I and II	1.9%
360	Putaminal Hemorrhage	1.9%
361	Shy-Drager Syndrome	1.9%
362	Purpura, Hyperglobulinemic	1.9%
363	Dementia, Vascular	1.8%
364	Behcet Syndrome	1.7%
365	Waldenstrom Macroglobulinemia	1.6%
366	Multiple Myeloma	1.6%
367	Pituitary Apoplexy	1.6%
368	Granulomatosis with polyangiitis	1.6%
369	Cysticercosis	1.6%
370	Hypodermyiasis	1.6%
371	Schistosomiasis japonica	1.6%
372	Schistosomiasis mansoni	1.6%
373	Sparganosis	1.6%
374	Ascaridida Infections	1.6%
375	Oxyurida Infections	1.6%
376	Cerebral Amyloid Angiopathy	1.6%
377	Lupus Vasculitis, Central Nervous System	1.5%
378	Ataxia Telangiectasia	1.5%
379	Pseudoxanthoma Elasticum	1.5%
380	Rheumatoid Vasculitis	1.4%
381	Ascariasis	1.1%
382	Filariasis	1.1%
383	Gnathostomiasis	1.1%
384	Hookworm Infections	1.1%
385	Oxyuriasis	1.1%
386	Strongyloidiasis	1.1%
387	Trichinellosis	1.1%
388	Trichostrongyloidiasis	1.1%
389	Hematoma, Subdural	1%
390	Hematoma, Epidural, Cranial	1%
391	Hematoma, Subdural, Intracranial	0.9%
392	Hematoma, Subdural, Chronic	0.9%
393	Hematoma, Subdural, Acute	0.9%
394	Brain Hemorrhage, Traumatic	0.9%
395	MELAS Syndrome	0.9%
396	Loiasis	0.8%
397	Enterobiasis	0.8%
398	Fabry Disease	0.7%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120234