MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Pigmentation Disorders

(UMLS:C0549567)

Definition:: Diseases affecting PIGMENTATION, including SKIN PIGMENTATION.
UMLS ID:: C0549567
MeSH ID:: D010859

Classification 1:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.621

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.755

Synonym(s)

Pigmentation Disorders

Disorder of pigmentation

Disorder of pigmentation, unspecified

Pigment alteration

Pigment alteration, NOS

Pigmentation disorder

Pigmentation disorders

disorder; pigmentation

disorders pigmentation

10.

pigment disorder

11.

pigment disorders

12.

pigmentation disorder

13.

pigmentation disorders

14.

pigmentation; disorder

Associated Drug(s)

	Name	Reference(s)	Data Source
1	2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine	19218331	CTD
2	3,3',5-triiodothyroacetic acid	29458080	CTD
3	Amiodarone	16461825	CTD
4	Benzocaine	20565405	CTD
5	Doxycycline	17103211	CTD
6	Hydroxyurea	12894095	CTD
7	Minocycline	2335590 4075574 10615019	CTD
8	Oxamic Acid	29458080	CTD
9	Pentazocine	8877940	CTD
10	Phenazopyridine	View details 4406341 5410400 7235788 16897003	CTD
11	Polychlorinated Dibenzodioxins	22403156	CTD
12	Triiodothyronine	29458080	CTD
13	Vitamin A	19648781 19852122	CTD
14	bisphenol A	19218331 21269433	CTD
15	cupric chloride	21167140	CTD
16	neocuproine	21167140	CTD
17	tetraiodothyroacetic acid	29458080	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Pyoderma Gangrenosum	37%
2	Acantholysis	36.8%
3	Nephrogenic Fibrosing Dermopathy	36.8%
4	Nephrogenic Systemic Fibrosis	36.8%
5	Acne Vulgaris	31%
6	Contact Dermatitis	31%
7	Eczema	31%
8	Erythema Multiforme	31%
9	Infarction	31%
10	Intertrigo	31%
11	Neurodermatitis	31%
12	Postoperative Hemorrhage	31%
13	Rhinophyma	31%
14	Shock, Hemorrhagic	31%
15	Systemic Inflammatory Response Syndrome	31%
16	Perioral Dermatitis	31%
17	Acne	31%
18	Dermatitis, Phototoxic	30.2%
19	Pityriasis Lichenoides et Varioliformis Acuta	30.2%
20	Pityriasis Lichenoides	30.2%
21	Phototoxicity	30.2%
22	Ascites	28.6%
23	Breast Diseases	28.6%
24	Dermatitis	28.6%
25	Exanthema	28.6%
26	Facial Dermatoses	28.6%
27	Fibrosis	28.6%
28	Gliosis	28.6%
29	Growth Disorders	28.6%
30	Hair Diseases	28.6%
31	Hand Dermatoses	28.6%
32	Hemorrhage	28.6%
33	Hyperbilirubinemia	28.6%
34	Hyperplasia	28.6%
35	Hypomenorrhea	28.6%
36	Inflammation	28.6%
37	Intraoperative Complications	28.6%
38	Ischemia	28.6%
39	keratoacanthoma	28.6%
40	Keratosis	28.6%
41	Lithiasis	28.6%
42	Lupus Erythematosus, Cutaneous	28.6%
43	Malacoplakia	28.6%
44	Menstruation Disturbances	28.6%
45	Metaplasia	28.6%
46	Nail Diseases	28.6%
47	Nerve Degeneration	28.6%
48	Ochronosis	28.6%
49	Panniculitis	28.6%
50	Photosensitivity Disorders	28.6%
51	Polymenorrhea	28.6%
52	Postoperative Complications	28.6%
53	Prurigo	28.6%
54	Pyoderma	28.6%
55	Rosacea	28.6%
56	Systemic Scleroderma	28.6%
57	Sclerosis	28.6%
58	Sebaceous Gland Diseases	28.6%
59	Shock	28.6%
60	Skin Diseases, Vesiculobullous	28.6%
61	Skin Ulcer	28.6%
62	Sweat Gland Diseases	28.6%
63	Ulcer	28.6%
64	Polydipsia	28.6%
65	Skin Diseases, Papulosquamous	28.6%
66	Skin Diseases, Vascular	28.6%
67	Acneiform Eruptions	28.6%
68	Hyperammonemia	28.6%
69	Hyperamylasemia	28.6%
70	Teratogenesis	28.6%
71	Cardiac Death	28.6%
72	Ocular Rosacea	28.6%
73	Hypovolemia	28.6%
74	Subcorneal pustular dermatosis	28.6%
75	Hyperuricemia	28.6%
76	Leukoaraiosis	28.6%
77	Erythematotelangiectatic Rosacea	28.6%
78	Papulopustular Rosacea	28.6%
79	Chronic Actinic Dermatitis	28.6%
80	Morphea	28.6%
81	Dysbacteriosis	28.6%
82	Delayed Graft Function	28.6%
83	Cirrhosis	28.6%
84	Neointima	28.6%
85	Dysbiosis	28.6%
86	Foot Ulcer	28.2%
87	Granuloma Annulare	27.9%
88	Pruritus	26.3%
89	Erythema	26.3%
90	Necrolytic Migratory Erythema	26.3%
91	Cutaneous Fistula	26.3%
92	Dermatitis, Atopic	26.2%
93	Epidermolysis Bullosa	26.2%
94	Sudden infant death syndrome	25.4%
95	Dermatitis, Irritant	25.4%
96	Acne Conglobata	25.4%
97	Dermatitis Herpetiformis	25%
98	Dermatitis, Photoallergic	25%
99	Panniculitis, Lupus Erythematosus	24.7%
100	Acrodermatitis	24.7%
101	Sebaceous Gland Neoplasms	24.7%
102	Porokeratosis	24.7%
103	Gianotti-Crosti Syndrome	24.7%
104	Keratoderma, Palmoplantar	24.7%
105	Necrobiosis Lipoidica Diabeticorum	23.2%
106	Vascular Remodeling	22.9%
107	Diaper Rash	22.7%
108	Extravasation of Diagnostic and Therapeutic Materials	22.2%
109	Foot Diseases	22.2%
110	Menorrhagia	22.2%
111	Neoplastic Processes	22.2%
112	Necrosis	21.4%
113	Skin Abnormalities	21.4%
114	Skin Diseases, Infectious	21.4%
115	Skin Neoplasms	21.4%
116	Granulomatosis, Orofacial	21.4%
117	Respiratory Aspiration	21.4%
118	Dermatitis, Occupational	21.1%
119	Chromosome Aberrations	21.1%
120	Dehydration	21.1%
121	Granuloma	21.1%
122	Leukocytosis	21.1%
123	Lipomatosis	21.1%
124	Pleocytosis	21.1%
125	Acute Disease	20.9%
126	Acute-Phase Reaction	20.9%
127	Amenorrhea	20.9%
128	Anhidrosis	20.9%
129	Cholesteatoma	20.9%
130	Chronic disease	20.9%
131	Critical Illness	20.9%
132	Sudden death	20.9%
133	Pressure Ulcer	20.9%
134	Fat necrosis	20.9%
135	Folliculitis	20.9%
136	Foot Dermatoses	20.9%
137	Gangrene	20.9%
138	Graft Occlusion, Vascular	20.9%
139	Granuloma, Plasma Cell	20.9%
140	Gynecomastia	20.9%
141	Hematoma	20.9%
142	Hypertrichosis	20.9%
143	Hypohidrosis	20.9%
144	Hypotrichosis	20.9%
145	Iatrogenic Disease	20.9%
146	Leg Ulcer	20.9%
147	Miliaria	20.9%
148	Multiple Organ Failure	20.9%
149	Oligomenorrhea	20.9%
150	Parakeratosis	20.9%
151	Parapsoriasis	20.9%
152	Pityriasis	20.9%
153	Premenstrual syndrome	20.9%
154	Psoriasis	20.9%
155	Recurrence	20.9%
156	Retrograde Degeneration	20.9%
157	Retroperitoneal fibrosis	20.9%
158	Serositis	20.9%
159	Subcutaneous Emphysema	20.9%
160	Surgical Wound Dehiscence	20.9%
161	Syndrome	20.9%
162	Wallerian Degeneration	20.9%
163	Sweet Syndrome	20.9%
164	Hidradenitis	20.9%
165	Pyogenic granuloma	20.9%
166	Onycholysis	20.9%
167	Miliaria Rubra	20.9%
168	Lichenoid Eruptions	20.9%
169	Exsanguination	20.9%
170	Disease Progression	20.9%
171	Seroma	20.9%
172	Chloracne	20.9%
173	Premenstrual Tension	20.9%
174	Delayed Emergence from Anesthesia	20.9%
175	Infant Death	20.9%
176	Anastomotic Leak	20.9%
177	Intraoperative Awareness	20.9%
178	Hirsutism	20.7%
179	Lupus Erythematosus, Discoid	20.7%
180	Xeroderma	20.7%
181	Incisional hernia	20.7%
182	Scleroderma, Limited	20.7%
183	jaundice	20.7%
184	Chromosomal Instability	20.6%
185	Erythema Induratum	20.4%
186	Dermatitis, Allergic Contact	20.3%
187	Papillon-Lefevre Disease	20.1%
188	Alopecia	20%
189	Androgenetic Alopecia	20%
190	Pain, Postoperative	19.7%
191	Endotoxic shock	19.2%
192	Septic Shock	19.2%
193	Toxic Shock Syndrome	19.2%
194	Dysmenorrhea	19.1%
195	Failed Back Surgery Syndrome	19.1%
196	Postoperative Nausea and Vomiting	18.9%
197	Erythema Infectiosum	18.9%
198	Exanthema Subitum	18.8%
199	Toxic Epidermal Necrolysis	18.7%
200	Stevens-Johnson Syndrome	18.7%
201	Erythema Nodosum	18.4%
202	Xeroderma Pigmentosum	18.4%
203	Dermatomyositis	18.3%
204	Cutis Laxa	18.1%
205	Tinea Capitis	17.5%
206	Onychomycosis	17.5%
207	Ectodermal Dysplasia	17.5%
208	Aplasia Cutis Congenita	17.5%
209	Genomic Instability	17.4%
210	Hyperkeratosis, Epidermolytic	17.2%
211	Tissue Adhesions	17.2%
212	Lichen Planus	17.2%
213	Pityriasis Rosea	17.2%
214	Pityriasis Rubra Pilaris	17.2%
215	Lichen Nitidus	17.2%
216	Hematoma, Epidural, Spinal	17.2%
217	Eye Hemorrhage	17.1%
218	Jaundice, Obstructive	16.9%
219	Muscle Weakness	16.8%
220	Chromosome Fragility	16.7%
221	Hemoptysis	16.7%
222	Pseudoxanthoma Elasticum	16.6%
223	Mastocytosis	16.6%
224	Ecchymosis	16.4%
225	Petechiae	16.4%
226	Purpura	16.4%
227	Livedo Reticularis	16.4%
228	Azotemia	16.4%
229	Asphyxia	16.4%
230	Granuloma, Respiratory Tract	16.4%
231	Shock, Traumatic	16.4%
232	Tinea Pedis	15.8%
233	Breast Cyst	15.8%
234	Disease susceptibility	15.8%
235	Ecthyma	15.8%
236	Fetal Death	15.8%
237	Foreign-Body Reaction	15.8%
238	Gastrointestinal Hemorrhage	15.8%
239	Hemarthrosis	15.8%
240	Hemoperitoneum	15.8%
241	Hemothorax	15.8%
242	Actinic keratosis	15.8%
243	Neoplasm Invasiveness	15.8%
244	Neoplasm Metastasis	15.8%
245	Neoplasm Recurrence, Local	15.8%
246	Pemphigoid, Benign Mucous Membrane	15.8%
247	Pemphigus	15.8%
248	Piedra	15.8%
249	Postpericardiotomy Syndrome	15.8%
250	Prosthesis Failure	15.8%
251	Reperfusion Injury	15.8%
252	Sunburn	15.8%
253	Injection Site Reaction	15.8%
254	Retrobulbar Hemorrhage	15.8%
255	Aseptic Necrosis of Bone	15.8%
256	Peritoneal Fibrosis	15.8%
257	Carcinogenesis	15.8%
258	Neurogenic Inflammation	15.8%
259	Perinatal death	15.8%
260	Infusion site reaction	15.8%
261	Corneal Endothelial Cell Loss	15.8%
262	Encapsulating Peritoneal Sclerosis	15.8%
263	Vasoplegia	15.8%
264	Suppuration	15.8%
265	Metastasis	15.8%
266	Sinus Arrhythmia	15.5%
267	Atrial Fibrillation	15.5%
268	Atrial Flutter	15.5%
269	Dental Pulp Necrosis	15.5%
270	Granuloma, Foreign-Body	15.5%
271	Lactation Disorder	15.5%
272	Mastitis	15.5%
273	Mediastinal Emphysema	15.5%
274	Surgical Wound Infection	15.5%
275	Urticaria	15.5%
276	Ventricular Fibrillation	15.5%
277	Ventricular Flutter	15.5%
278	Parasystole	15.5%
279	Paroxysmal atrial fibrillation	15.5%
280	Facies	15.5%
281	Bradycardia	15.5%
282	Embryo Loss	15.5%
283	Alopecia Areata	15.4%
284	Hematoma, Subdural, Spinal	15.4%
285	Adiposis Dolorosa	15.4%
286	Afferent Loop Syndrome	15.4%
287	Pruritus Vulvae	15.4%
288	Sex Chromosome Aberrations	15.4%
289	Short Bowel Syndrome	15.4%
290	Uterine hemorrhage	15.4%
291	No-Reflow Phenomenon	15.4%
292	Mastocytoma	15.3%
293	Pruritus Ani	15.3%
294	Connective Tissue Diseases	15%
295	Signs and Symptoms	15%
296	Pathological Conditions, Anatomical	15%
297	Ichthyosis, X-Linked	14.5%
298	Sjogren-Larsson Syndrome	14.4%
299	Hidradenitis Suppurativa	14.4%
300	Sick Sinus Syndrome	14.2%
301	Trisomy	14.2%
302	Keloid	14.2%
303	Cardiotoxicity	14%
304	Behcet Syndrome	14%
305	Epistaxis	14%
306	Hematemesis	13.5%
307	Purpura Fulminans	13.4%
308	Cellulitis	13.1%
309	Cross Infection	13%
310	Hyphema	13%
311	Retinal Neovascularization	13%
312	Septicemia	13%
313	Sweating, Gustatory	13%
314	Vitreous Hemorrhage	13%
315	Auriculotemporal Syndrome	13%
316	Sepsis	13%
317	Drowning	12.9%
318	Abscess	12.8%
319	Empyema	12.8%
320	Femur Head Necrosis	12.8%
321	Fetal Resorption	12.8%
322	Lymphatic Metastasis	12.8%
323	Neoplasms, Unknown Primary	12.8%
324	Lice Infestations	12.8%
325	Peptic Ulcer Hemorrhage	12.8%
326	Varicose Ulcer	12.8%
327	Sudden Cardiac Death	12.8%
328	Leukemic Infiltration	12.8%
329	Breast Neoplasms, Male	12.8%
330	Premenstrual Dysphoric Disorder	12.8%
331	Choroidal Neovascularization	12.8%
332	Primary Graft Dysfunction	12.8%
333	Neoplasm Micrometastasis	12.8%
334	Triple Negative Breast Neoplasms	12.8%
335	Dumping Syndrome	12.7%
336	Cicatrix, Hypertrophic	12.7%
337	Sinus Arrest, Cardiac	12.7%
338	Galactorrhea	12.7%
339	Metrorrhagia	12.7%
340	Dermatomycoses	12.5%
341	Fetal Growth Retardation	12.5%
342	Mucocutaneous Lymph Node Syndrome	12.5%
343	Skin Diseases, Bacterial	12.5%
344	DNA Degradation, Necrotic	12.5%
345	Aneuploidy	12.4%
346	Polyploidy	12.4%
347	Microsatellite Instability	12.4%
348	Hematoma, Subdural	12.3%
349	Hematoma, Epidural, Cranial	12.3%
350	Drug Eruptions	12.3%
351	Heart Block	12.3%
352	Lipodystrophy	12.3%
353	Tachycardia	12.3%
354	Tachyarrhythmia	12.3%
355	Malignant Atrophic Papulosis	12.3%
356	Cicatrix	12.3%
357	Hematuria	12.2%
358	Chromosome Breakage	12.2%
359	Brain Death	12.2%
360	Polyarteritis Nodosa	12.2%
361	Shock, Cardiogenic	12.2%
362	Takayasu Arteritis	12.2%
363	Erythema Chronicum Migrans	12.1%
364	Viremia	12.1%
365	Parasitemia	12.1%
366	Lichen Planus, Oral	11.7%
367	Phantom pain	11.4%
368	Phantom Limb Pain	11.4%
369	Mycetoma	11%
370	Hematoma, Subdural, Intracranial	11%
371	Hematoma, Subdural, Chronic	11%
372	Hematoma, Subdural, Acute	11%
373	Retinal Hemorrhage	10.5%
374	Nail-Patella Syndrome	10.5%
375	Giant Cell Epulis	10.4%
376	Choroid Hemorrhage	10.3%
377	Larva Migrans	10.3%
378	Leishmaniasis	10.3%
379	Melena	10.3%
380	Molluscum Contagiosum	10.3%
381	Porphyrias, Hepatic	10.3%
382	Angioedema	10.3%
383	Onchocerciasis	10.2%
384	Postpartum Hemorrhage	10.2%
385	Long QT Syndrome	10.2%
386	Chromoblastomycosis	10.1%
387	Dermatophytosis	10.1%
388	Gingival Hemorrhage	10.1%
389	Sporotrichosis	10.1%
390	Tinea	10.1%
391	Tinea Versicolor	10.1%
392	Trichophytosis	10.1%
393	Hyalohyphomycosis	10.1%
394	Monosomy	10.1%
395	Tetraploidy	10.1%
396	Stillbirth	10.1%
397	Urticaria Pigmentosa	10.1%
398	Adams-Stokes Syndrome	10.1%
399	Atrioventricular Block	10.1%
400	Bundle-Branch Block	10.1%
401	Atrial Premature Complexes	10.1%
402	Sinoatrial Block	10.1%
403	Tachycardia, Paroxysmal	10.1%
404	Supraventricular tachycardia	10.1%
405	Tachycardia, Ventricular	10.1%
406	Tachycardia, Reciprocating	10.1%
407	Acute Generalized Exanthematous Pustulosis	10.1%
408	Subarachnoid Hemorrhage	10%
409	Cerebral Hemorrhage	10%
410	Micronuclei, Chromosome-Defective	10%
411	Thrombocytopenic purpura	9.8%
412	Asthenia	9.5%
413	Body Temperature Changes	9.5%
414	Calculi	9.5%
415	Collagen Diseases	9.5%
416	Cyanosis	9.5%
417	Edema	9.5%
418	Failure to Thrive	9.5%
419	Fatigue	9.5%
420	Feminization	9.5%
421	Fetal Distress	9.5%
422	Hernia	9.5%
423	Hypertrophy	9.5%
424	Mixed Connective Tissue Disease	9.5%
425	Motion Sickness	9.5%
426	Nails, Malformed	9.5%
427	polyps	9.5%
428	Purpura, Hyperglobulinemic	9.5%
429	Rupture, Spontaneous	9.5%
430	Signs and Symptoms, Digestive	9.5%
431	Signs and Symptoms, Respiratory	9.5%
432	Skin Manifestations	9.5%
433	Chills	9.5%
434	Lassitude	9.5%
435	Mucinoses	9.5%
436	Enterocele	9.5%
437	Atheroma	9.5%
438	Pseudophakia	9.5%
439	Urological Manifestations	9.5%
440	Stenosis	9.5%
441	Facial asymmetry	9.5%
442	Mobility Limitation	9.5%
443	Somnolence	9.5%
444	Plaque, Amyloid	9.5%
445	Plaque, Atherosclerotic	9.5%
446	Abdominal Pain	9.4%
447	Bacteremia	9.3%
448	Cell Transformation, Viral	9.2%
449	Fungemia	9.2%
450	Leishmaniasis, Cutaneous	9.1%
451	Eczema Herpeticum	9.1%
452	Fusariosis	9%
453	Tachycardia, Atrioventricular Nodal Reentry	9%
454	Tachycardia, Ectopic Atrial	9%
455	Tachycardia, Ectopic Junctional	9%
456	Sinus Tachycardia	9%
457	Torsades de Pointes	9%
458	Accelerated Idioventricular Rhythm	9%
459	Subacute Combined Degeneration	8.8%
460	Eosinophilic Granuloma	8.7%
461	Warts	8.7%
462	Endotoxemia	8.6%
463	Purpura, Thrombotic Thrombocytopenic	8.5%
464	Hereditary Angioedema Type III	8.5%
465	Hereditary Angioedema Types I and II	8.5%
466	Candidiasis, Chronic Mucocutaneous	8.4%
467	Cutaneous Candidiasis	8.4%
468	Erysipelas	8.4%
469	Serum Sickness	8.4%
470	Staphylococcal Skin Infections	8.4%
471	Variegate Porphyria	8.4%
472	Acute intermittent porphyria	8.4%
473	Porphyria Cutanea Tarda	8.4%
474	Erythrasma	8.4%
475	Carcinoma, Lobular	8.4%
476	Arthritis, Psoriatic	8.3%
477	Romano-Ward Syndrome	8.3%
478	CREST Syndrome	8.3%
479	Abdomen, Acute	8%
480	Kernicterus	7.7%
481	Angioedemas, Hereditary	7.6%
482	Eye pain	7.6%
483	Epidermodysplasia Verruciformis	7.6%
484	Herpes Labialis	7.6%
485	Diabetic Foot	7.5%
486	Muscular Atrophy	7.5%
487	Granuloma, Laryngeal	7.5%
488	Staphylococcal Scalded Skin Syndrome	7.4%
489	Cartilage Diseases	7.4%
490	Cyst	7.4%
491	Eye Manifestations	7.4%
492	Neurologic Manifestations	7.4%
493	Rheumatism	7.4%
494	Chondromalacia	7.4%
495	Renal Colic	7.3%
496	Myocardial Reperfusion Injury	7.2%
497	Leukoplakia	7.1%
498	Lupus Erythematosus, Systemic	7.1%
499	Cardiac Output, High	7.1%
500	Myocardial Stunning	7.1%
501	Reticulocytosis	7.1%
502	Overlap syndrome	7.1%
503	Low Cardiac Output Syndrome	7.1%
504	Airway Remodeling	7.1%
505	Ventricular Remodeling	7%
506	Anorexia	7%
507	Anoxia	7%
508	carbuncle	7%
509	Constipation	7%
510	Diarrhea	7%
511	Dyspepsia	7%
512	Eructation	7%
513	Fever	7%
514	Flatulence	7%
515	Flushing	7%
516	Halitosis	7%
517	Heartburn	7%
518	Diaphragmatic Hernia	7%
519	Hiccough	7%
520	Hypercalciuria	7%
521	Hypercapnia	7%
522	Hyperphagia	7%
523	Intestinal Polyps	7%
524	Nausea	7%
525	Pallor	7%
526	Psychophysiologic Disorders	7%
527	Splenomegaly	7%
528	Vomiting	7%
529	Hypocapnia	7%
530	Dyschezia	7%
531	Hypoxia	7%
532	Hyperoxia	7%
533	Scleromyxedema	7%
534	Lower Urinary Tract Symptoms	7%
535	Hypoxemia	7%
536	Urinoma	7%
537	Intermittent Claudication	7%
538	Albinism	6.7%
539	Autoimmune thrombocytopenia	6.7%
540	Immune thrombocytopenic purpura	6.7%
541	Giant Cell Arteritis	6.6%
542	Temporal Arteritis	6.6%
543	Condylomata Acuminata	6.5%
544	Furunculosis	6.4%
545	furuncle	6.4%
546	Sarcopenia	6.4%
547	Impetigo	6.4%
548	Blastomycosis	6.3%
549	HIV-Associated Lipodystrophy Syndrome	6.2%
550	Philadelphia Chromosome	6.1%
551	Candidemia	6%
552	Waterhouse-Friderichsen Syndrome	6%
553	Back Pain	5.7%
554	Bulimia	5.7%
555	Neck Pain	5.7%
556	Chest Pain	5.7%
557	Colonic Polyps	5.7%
558	Dizziness	5.7%
559	Dysuria	5.7%
560	Facial Pain	5.7%
561	Fever of Unknown Origin	5.7%
562	Flank Pain	5.7%
563	Headache	5.7%
564	Nocturia	5.7%
565	Pain, Intractable	5.7%
566	Pelvic Pain	5.7%
567	Snoring	5.7%
568	Chronic pain	5.7%
569	Lightheadedness	5.7%
570	Pain, Referred	5.7%
571	Prostatism	5.7%
572	Throbbing Headache	5.7%
573	Labor Pain	5.7%
574	Cancer Pain	5.7%
575	Nociceptive Pain	5.7%
576	Rhinoscleroma	5.7%
577	Hypergammaglobulinemia	5.6%
578	Basal Ganglia Hemorrhage	5.5%
579	Dupuytren Contracture	5.5%
580	Diverticulum	5.5%
581	Diverticulosis	5.5%
582	Respiratory Tract Fistula	5.5%
583	Gait Ataxia	5.3%
584	Apnea	5.3%
585	Cheyne-Stokes Respiration	5.3%
586	Decerebrate State	5.3%
587	Dyspnea	5.3%
588	Cardiomegaly	5.3%
589	Hemiparesis	5.3%
590	Hepatomegaly	5.3%
591	Hyperventilation	5.3%
592	Meningism	5.3%
593	Mesenteric Panniculitis	5.3%
594	Mouth Breathing	5.3%
595	Panniculitis, Peritoneal	5.3%
596	Paresis	5.3%
597	Parovarian Cyst	5.3%
598	Seizures	5.3%
599	Sensation Disorders	5.3%
600	Sneezing	5.3%
601	Spermatocele	5.3%
602	Tietze's Syndrome	5.3%
603	Oral Fistula	5.3%
604	Orbital Cellulitis	5.3%
605	Complex partial seizures	5.3%
606	Tachypnea	5.3%
607	Monoparesis	5.3%
608	Gait Disorders, Neurologic	5.3%
609	Neuromuscular Manifestations	5.3%
610	Myxoid cyst	5.3%
611	Cardiac Hypertrophy	5.3%
612	Putaminal Hemorrhage	5.2%
613	Edema, Cardiac	5.2%
614	Mental Fatigue	5.2%
615	Myxedema	5.2%
616	Orthostatic intolerance	5.2%
617	Hypoventilation	5.2%
618	Emaciation	5.1%
619	Low Back Pain	5.1%
620	Visceral Pain	5.1%
621	Vaginal Fistula	5.1%
622	Rectocele	5.1%
623	Body Weight Changes	5.1%
624	Menkes Kinky Hair Syndrome	4.9%
625	Cachexia	4.8%
626	Hoarseness	4.7%
627	Akathisia	4.5%
628	Restlessness	4.5%
629	Psychomotor Agitation	4.5%
630	Sleep Wake Disorders	4.5%
631	Vesicovaginal Fistula	4.5%
632	Gait Apraxia	4.4%
633	Biliary Fistula	4.3%
634	Gastric Fistula	4.3%
635	Pupil Disorders	4.3%
636	Congenital diaphragmatic hernia	4.3%
637	Morning Sickness	4.3%
638	Neurobehavioral Manifestations	4.3%
639	Anosmia	4.3%
640	Ataxia	4.3%
641	Athetosis	4.3%
642	Catalepsy	4.3%
643	Dental Fistula	4.3%
644	Dystonia	4.3%
645	Hemiplegia	4.3%
646	Locked-In Syndrome	4.3%
647	Muscle Hypertonia	4.3%
648	Muscle hypotonia	4.3%
649	Myoclonus	4.3%
650	Myotonia	4.3%
651	Neuralgia	4.3%
652	Oroantral Fistula	4.3%
653	Paraplegia	4.3%
654	Pseudobulbar Palsy	4.3%
655	Quadriplegia	4.3%
656	Spasm	4.3%
657	Spastic Paraplegia	4.3%
658	Status Epilepticus	4.3%
659	Taste Disorders	4.3%
660	Tremor	4.3%
661	Monoplegia	4.3%
662	Hypokinesia	4.3%
663	Left Ventricular Hypertrophy	4.3%
664	Gastroparesis	4.3%
665	Right Ventricular Hypertrophy	4.3%
666	Paraparesis	4.3%
667	Bradykinesia	4.3%
668	Waxy flexibility	4.3%
669	Action Tremor	4.3%
670	Resting Tremor	4.3%
671	Dysosmia	4.3%
672	Quadriparesis	4.3%
673	Olfaction Disorders	4.3%
674	Myokymia	4.3%
675	Somatosensory Disorders	4.3%
676	Neuropathic pain	4.3%
677	Hyperkinesia	4.3%
678	Intention tremor	4.3%
679	Rectal Prolapse	4.2%
680	Uterine Prolapse	4.2%
681	Vaginal Prolapse	4.2%
682	Nasal Polyps	4.2%
683	Osteochondritis	4.2%
684	Polymyalgia Rheumatica	4.2%
685	Weight Gain	4.2%
686	Pleural Rub	4.2%
687	Rales	4.2%
688	Respiratory Sounds	4.2%
689	Rhonchi	4.2%
690	Stridor	4.2%
691	Wheezing	4.2%
692	Asterixis	4.2%
693	Ballismus	4.2%
694	Osteogenesis Imperfecta	4.1%
695	Vertigo	4.1%
696	Pain	4.1%
697	Ache	4.1%
698	Meningocele	4.1%
699	Oliguria	4.1%
700	Polyuria	4.1%
701	Proteinuria	4.1%
702	Urinary Calculi	4.1%
703	Encephalocele	4.1%
704	Underweight	4%
705	Overweight	4%
706	Alexia	4%
707	Dyslexia	4%
708	Umbilical hernia	3.9%
709	Toothache	3.9%
710	Body Weight	3.8%
711	Hyperemesis Gravidarum	3.8%
712	Dysgeusia	3.8%
713	Formication	3.8%
714	Hyperalgesia	3.8%
715	Hyperesthesia	3.8%
716	Hypesthesia	3.8%
717	Language Disorders	3.8%
718	Numbness	3.8%
719	Paresthesia	3.8%
720	Paraparesis, Spastic	3.8%
721	Trismus	3.8%
722	Epilepsia Partialis Continua	3.8%
723	Hypogeusia	3.8%
724	Brown-Sequard Syndrome	3.8%
725	Lockjaw	3.8%
726	Allodynia	3.8%
727	Ageusia	3.8%
728	Alice in Wonderland Syndrome	3.7%
729	Agraphia	3.6%
730	Anomia	3.6%
731	Cluttering	3.6%
732	Language Development Disorders	3.6%
733	Speech Disorders	3.6%
734	Syncope	3.6%
735	Stupor	3.6%
736	Dysgraphia	3.6%
737	Presyncope	3.6%
738	Dyslalia	3.6%
739	Vision Disorders	3.5%
740	Metamorphopsia	3.5%
741	Visual Impairment	3.5%
742	Voice Disorders	3.5%
743	Voice Disturbance	3.5%
744	Bronchial Fistula	3.5%
745	Metatarsalgia	3.5%
746	Pancreatic Fistula	3.5%
747	Rheumatoid Arthritis	3.5%
748	Juvenile arthritis	3.5%
749	Anisocoria	3.4%
750	Aphasia	3.4%
751	Articulation Disorders	3.4%
752	Confusion	3.4%
753	Echolalia	3.4%
754	Facial paralysis	3.4%
755	Gagging	3.4%
756	Intestinal Fistula	3.4%
757	Lethargy	3.4%
758	Memory Disorders	3.4%
759	Muscle Cramp	3.4%
760	Perceptual Disorders	3.4%
761	Psychomotor Disorders	3.4%
762	Stuttering	3.4%
763	Tonic Pupil	3.4%
764	Anhedonia	3.4%
765	Disorientation	3.4%
766	Gastroschisis	3.4%
767	Enterocutaneous Fistula	3.4%
768	Fetal Hypoxia	3.4%
769	Facial Paresis	3.4%
770	Memory Loss	3.4%
771	Hemisensory Neglect	3.4%
772	Dysphasia	3.4%
773	Dysacusis	3.4%
774	Dyspnea, Paroxysmal	3.4%
775	Mastodynia	3.4%
776	Respiratory Paralysis	3.4%
777	Salivary Gland Fistula	3.4%
778	Dysarthria	3.4%
779	Leukoplakia, Oral	3.4%
780	Noonan Syndrome	3.4%
781	Chorea	3.4%
782	Cystocele	3.4%
783	Rheumatoid Nodule	3.4%
784	Tetany	3.4%
785	Urinary Incontinence	3.4%
786	Breakthrough Pain	3.4%
787	Lupus Nephritis	3.3%
788	Albuminuria	3.3%
789	Hemoglobinuria	3.3%
790	Diplopia	3.1%
791	Muscle Rigidity	3.1%
792	Muscle Spasticity	3.1%
793	Scotoma	3.1%
794	Photophobia	3.1%
795	Cogwheel Rigidity	3.1%
796	Hemifacial Spasm	3.1%
797	Amaurosis	3.1%
798	Blindness	3.1%
799	Nuchal Rigidity	3.1%
800	Angina Pectoris	3.1%
801	Marfan Syndrome	3%
802	Agnosia	3%
803	Apraxias	3%
804	Hallucinations	3%
805	Hemianopsia	3%
806	Hyperacusis	3%
807	Tinnitus	3%
808	Visual Agnosia	3%
809	Anosognosia	3%
810	Wernicke-Korsakoff Syndrome	3%
811	Phonophobia	3%
812	Hearing Loss	3%
813	Cerebellar Ataxia	3%
814	Torticollis	3%
815	Sciatica	3%
816	Urge Incontinence	3%
817	Laryngomalacia	3%
818	Tardive Dyskinesia	3%
819	Pectus carinatum	3%
820	Homocystinuria	2.9%
821	Jet Lag Syndrome	2.9%
822	Reflex, Abnormal	2.9%
823	Hyporeflexia	2.9%
824	Hyperreflexia	2.9%
825	Consciousness Disorders	2.9%
826	Mental Retardation	2.9%
827	Depressed Level of Consciousness	2.9%
828	Mental deficiency	2.9%
829	Intellectual Disability	2.9%
830	Catatonia	2.9%
831	Musculoskeletal Pain	2.9%
832	Ophthalmoplegia	2.9%
833	External Ophthalmoplegia	2.9%
834	Amaurosis Fugax	2.8%
835	Blindness, Cortical	2.8%
836	Dyscalculia	2.8%
837	Angina, Unstable	2.8%
838	Deafness	2.8%
839	Hearing Loss, Sudden	2.8%
840	Gerstmann Syndrome	2.8%
841	Hearing Loss, Bilateral	2.8%
842	Hearing Loss, High-Frequency	2.8%
843	Hearing Loss, Mixed Conductive-Sensorineural	2.8%
844	Prosopagnosia	2.8%
845	Apraxia, Ideomotor	2.8%
846	Persistent Vegetative State	2.8%
847	Charles Bonnet Syndrome	2.8%
848	Hearing Loss, Unilateral	2.8%
849	Complete Hearing Loss	2.8%
850	Alien Hand Syndrome	2.8%
851	Deaf Mutism	2.8%
852	Birth Weight	2.8%
853	Aphonia	2.8%
854	Arthralgia	2.8%
855	Sleep Deprivation	2.8%
856	Polyarthralgia	2.8%
857	Dysphonia	2.8%
858	Felty Syndrome	2.8%
859	Bronchomalacia	2.8%
860	Tracheomalacia	2.8%
861	Mutism	2.8%
862	Selective Mutism	2.8%
863	Cerebrospinal Fluid Otorrhea	2.8%
864	Cerebrospinal Fluid Rhinorrhea	2.8%
865	Obesity	2.8%
866	Angina Pectoris, Variant	2.7%
867	Alexia, Pure	2.7%
868	Amblyopia	2.5%
869	Amnesia	2.5%
870	Delirium	2.5%
871	Horner Syndrome	2.5%
872	Dissociative Amnesia	2.5%
873	Color blindness	2.5%
874	Global Amnesia	2.5%
875	Rectal Fistula	2.5%
876	Anal Fistula	2.5%
877	Shoulder Pain	2.5%
878	Pediatric Obesity	2.5%
879	Vocal Cord Paralysis	2.5%
880	Urinary Bladder Fistula	2.4%
881	Rheumatoid Vasculitis	2.4%
882	Retrograde amnesia	2.4%
883	Amnesia, Anterograde	2.4%
884	Mucopolysaccharidosis III	2.3%
885	Hydrops Fetalis	2.2%
886	Akathisia, Drug-Induced	2.2%
887	Fetal Weight	2.2%
888	Myalgia	2.2%
889	Dyskinesia, Drug-Induced	2.1%
890	Sicca Syndrome	2.1%
891	Sjogren's Syndrome	2.1%
892	Alcohol Withdrawal Seizures	2.1%
893	Arteriovenous fistula	2.1%
894	Amnesia, Transient Global	2%
895	Auditory Perceptual Disorders	1.9%
896	Kidney Calculi	1.8%
897	Ureteral Calculi	1.8%
898	Ophthalmoplegic Migraine	1.7%
899	Progressive supranuclear palsy	1.7%
900	Mucopolysaccharidosis II	1.6%
901	Lupus Vasculitis, Central Nervous System	1.5%
902	Kearns-Sayre syndrome	1.2%

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