MetaADEDB 2.0 @ LMMD
Progesterone
(RJKFOVLPORLFTN-LEKSSAKUSA-N)
Structure
SMILES
O=C1CC[C@]2(C(=C1)CC[C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2C(=O)C)C)C
Type(s)
Approved; Vet_approved
ATC code(s)
G03DA04; G03FA04
Molecular Formula:
C21H30O2
Molecular Weight:
314.462
Log P:
4.7235
Hydrogen Bond Acceptor:
2
Hydrogen Bond Donor:
0
TPSA:
34.14
CAS Number(s):
57-83-0; 753497-20-0
Synonym(s)
1.
Progesterone
2.
Pregnenedione
3.
Progesterone, (13 alpha,17 alpha)-(+-)-Isomer
4.
Progesterone, (17 alpha)-Isomer
5.
Progesterone, (9 beta,10 alpha)-Isomer
External Link(s)
MeSHD011374
PubChem Compound5994
BindingDB8903
ChEBI17026
CHEMBLCHEMBL103
DrugBankDB00396
DrugCentral2279
IUPHAR/BPS Guide to PHARMACOLOGY2377
KEGGcpd:C00410
dr:D00066
Therapeutic Target DatabaseD07BSQ
ZINC4428529
Adverse Drug Event(s)
NameNumber of ReportsReference(s)Data Source
1Drug ineffectiveFAERS: 56
Canada Vigilance: 9		Canada Vigilance
US FAERS
2HeadacheFAERS: 43
Canada Vigilance: 3		Canada Vigilance
SIDER
US FAERS
3DizzinessFAERS: 42
Canada Vigilance: 4		2816478
11684377		CTD
SIDER
Canada Vigilance
US FAERS
4Drug exposure during pregnancyFAERS: 26OFFSIDES
US FAERS
5Vaginal DischargeFAERS: 26
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
6Product substitution issueFAERS: 22
Canada Vigilance: 1		Canada Vigilance
US FAERS
7HypersensitivityFAERS: 21SIDER
US FAERS
8Product quality issueFAERS: 20
Canada Vigilance: 5		Canada Vigilance
US FAERS
9Abdominal PainFAERS: 19
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
SIDER
US FAERS
10AnxietyFAERS: 17
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
SIDER
US FAERS
11Feeling abnormalFAERS: 17SIDER
US FAERS
12Maternal exposure during pregnancyFAERS: 17
Canada Vigilance: 2		Canada Vigilance
US FAERS
13NauseaFAERS: 17
Canada Vigilance: 3		Canada Vigilance
OFFSIDES
SIDER
US FAERS
14Product storage errorFAERS: 17US FAERS
15PruritusFAERS: 17SIDER
US FAERS
16FatigueFAERS: 16OFFSIDES
SIDER
US FAERS
17SomnolenceFAERS: 13
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
18Incorrect route of drug administrationFAERS: 12US FAERS
19PainFAERS: 12
Canada Vigilance: 1		8918680CTD
OFFSIDES
SIDER
Canada Vigilance
US FAERS
20UrticariaFAERS: 12SIDER
US FAERS
21MalaiseFAERS: 11SIDER
US FAERS
22VomitingFAERS: 11
Canada Vigilance: 3		Canada Vigilance
SIDER
US FAERS
23Product use issueFAERS: 10US FAERS
24MetrorrhagiaFAERS: 9
Canada Vigilance: 1		11684377CTD
SIDER
Canada Vigilance
US FAERS
25Night sweatsFAERS: 9SIDER
US FAERS
26PregnancyFAERS: 9SIDER
US FAERS
27AstheniaFAERS: 8
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
28Back PainFAERS: 8SIDER
US FAERS
29HypospadiasFAERS: 8US FAERS
30Product use in unapproved indicationFAERS: 8
Canada Vigilance: 1		Canada Vigilance
US FAERS
31TremorFAERS: 8SIDER
US FAERS
32Unevaluable eventFAERS: 8US FAERS
33ArthralgiaFAERS: 7
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
34Eosinophilic PneumoniaFAERS: 7US FAERS
35ErythemaFAERS: 7SIDER
US FAERS
36Incorrect dose administeredFAERS: 7US FAERS
37Medication residue presentFAERS: 7US FAERS
38MyalgiaFAERS: 7SIDER
US FAERS
39SyncopeFAERS: 7
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
40AlopeciaFAERS: 6
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
41Cerebrovascular accidentFAERS: 6US FAERS
42Drug prescribing errorFAERS: 6US FAERS
43DysarthriaFAERS: 6SIDER
US FAERS
44SwellingFAERS: 6SIDER
US FAERS
45Visual ImpairmentFAERS: 6SIDER
US FAERS
46Vulvovaginal discomfortFAERS: 6OFFSIDES
SIDER
US FAERS
47AbasiaFAERS: 5US FAERS
48Abdominal discomfortFAERS: 5OFFSIDES
SIDER
US FAERS
49AngioedemaFAERS: 518302843CTD
SIDER
US FAERS
50Breast tendernessFAERS: 5OFFSIDES
SIDER
US FAERS
51Chest discomfortFAERS: 5US FAERS
52Drug dose omissionFAERS: 5US FAERS
53Medication ErrorFAERS: 5US FAERS
54MeningiomaFAERS: 5OFFSIDES
US FAERS
55Product physical issueFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
56VertigoFAERS: 5
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
57Wrong technique in product usage processFAERS: 5
Canada Vigilance: 1		Canada Vigilance
US FAERS
58Autoimmune dermatitisFAERS: 4US FAERS
59Contraindicated product administeredFAERS: 4
Canada Vigilance: 2		Canada Vigilance
US FAERS
60Drug dispensing errorFAERS: 4US FAERS
61EclampsiaFAERS: 4US FAERS
62Endometrial HyperplasiaFAERS: 4OFFSIDES
SIDER
US FAERS
63Expired product administeredFAERS: 4US FAERS
64FlatulenceFAERS: 4SIDER
US FAERS
65Inappropriate schedule of drug administrationFAERS: 4US FAERS
66Incorrect route of product administrationFAERS: 4US FAERS
67NervousnessFAERS: 4SIDER
US FAERS
68PalpitationsFAERS: 4SIDER
US FAERS
69Progesterone decreasedFAERS: 4OFFSIDES
US FAERS
70Accidental exposure to productFAERS: 3US FAERS
71AscitesFAERS: 3OFFSIDES
US FAERS
72Chest PainFAERS: 3SIDER
US FAERS
73ChromaturiaFAERS: 3US FAERS
74DiscomfortFAERS: 3SIDER
US FAERS
75DysgeusiaFAERS: 3OFFSIDES
US FAERS
76DyspepsiaFAERS: 3SIDER
US FAERS
77Ectopic PregnancyFAERS: 3US FAERS
78Emotional disorderFAERS: 3US FAERS
79Escherichia infectionFAERS: 3OFFSIDES
US FAERS
80HemiparesisFAERS: 3US FAERS
81HypotensionFAERS: 3SIDER
US FAERS
82InflammationFAERS: 315869954CTD
US FAERS
83Injection site painFAERS: 3US FAERS
84Injection site pruritusFAERS: 3OFFSIDES
US FAERS
85LethargyFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
86Memory impairmentFAERS: 3SIDER
US FAERS
87Mood swingsFAERS: 3SIDER
US FAERS
88Musculoskeletal stiffnessFAERS: 3US FAERS
89PancreatitisFAERS: 3
Canada Vigilance: 1		Canada Vigilance
US FAERS
90Product size issueFAERS: 3US FAERS
91Reaction to drug excipientsFAERS: 3US FAERS
92Therapeutic response unexpectedFAERS: 3US FAERS
93Throat irritationFAERS: 3US FAERS
94Urinary tract infectionFAERS: 3SIDER
US FAERS
95Uterine CancerFAERS: 3OFFSIDES
US FAERS
96Uterine spasmFAERS: 3SIDER
US FAERS
97Wrong drug administeredFAERS: 3US FAERS
98Wrong technique in drug usage processFAERS: 3US FAERS
99AcneFAERS: 2SIDER
US FAERS
100AgitationFAERS: 2US FAERS
101Altered state of consciousnessFAERS: 2US FAERS
102AphasiaFAERS: 2US FAERS
103Application site irritationFAERS: 2US FAERS
104AsthmaFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
105Blighted ovumFAERS: 2US FAERS
106Blood glucose increasedFAERS: 2SIDER
US FAERS
107Blood human chorionic gonadotropin decreasedFAERS: 2OFFSIDES
US FAERS
108BradycardiaFAERS: 2US FAERS
109Capsule physical issueFAERS: 2US FAERS
110Cardiac ArrestFAERS: 2US FAERS
111CellulitisFAERS: 2US FAERS
112ChillsFAERS: 2US FAERS
113ChokingFAERS: 2
Canada Vigilance: 2		Canada Vigilance
SIDER
US FAERS
114ConstipationFAERS: 2SIDER
US FAERS
115CryingFAERS: 2SIDER
US FAERS
116DeliriumFAERS: 2US FAERS
117Disease recurrenceFAERS: 2US FAERS
118DisorientationFAERS: 2SIDER
US FAERS
119Drug administration errorFAERS: 2US FAERS
120Drug ineffective for unapproved indicationFAERS: 2
Canada Vigilance: 1		Canada Vigilance
US FAERS
121DystoniaFAERS: 2US FAERS
122Ejection Fraction DecreasedFAERS: 2US FAERS
123Electrocardiogram abnormalFAERS: 2US FAERS
124Endometrial disorderFAERS: 2
Canada Vigilance: 1		Canada Vigilance
OFFSIDES
US FAERS
125Food AllergyFAERS: 2US FAERS
126Gluten sensitivityFAERS: 2US FAERS
127Hormone level abnormalFAERS: 2US FAERS
128HypokinesiaFAERS: 2US FAERS
129Idiopathic angioedemaFAERS: 2US FAERS
130Impaired work abilityFAERS: 2US FAERS
131InfectionFAERS: 2SIDER
US FAERS
132Injection site erythemaFAERS: 2OFFSIDES
US FAERS
133Injection site urticariaFAERS: 2OFFSIDES
US FAERS
134Intentional drug misuseFAERS: 2OFFSIDES
US FAERS
135Intercepted product storage errorFAERS: 2US FAERS
136Lip swellingFAERS: 2US FAERS
137Maternal exposure timing unspecifiedFAERS: 2US FAERS
138MenorrhagiaFAERS: 2SIDER
US FAERS
139MyoclonusFAERS: 2US FAERS
140NephrolithiasisFAERS: 2OFFSIDES
US FAERS
141Oropharyngeal painFAERS: 2OFFSIDES
US FAERS
142Pelvic InfectionFAERS: 2US FAERS
143Pharmaceutical product complaintFAERS: 2US FAERS
144PresyncopeFAERS: 2US FAERS
145Product formulation issueFAERS: 2US FAERS
146Product physical consistency issueFAERS: 2US FAERS
147Progesterone increasedFAERS: 2US FAERS
148Pulmonary EmbolismFAERS: 2SIDER
US FAERS
149Retinal vascular thrombosisFAERS: 2US FAERS
150SciaticaFAERS: 2US FAERS
151StressFAERS: 2US FAERS
152Suppressed lactationFAERS: 2US FAERS
153TinnitusFAERS: 2OFFSIDES
SIDER
US FAERS
154Tolosa-Hunt SyndromeFAERS: 2
Canada Vigilance: 2		Canada Vigilance
US FAERS
155Urinary RetentionFAERS: 2US FAERS
156Weight decreasedFAERS: 2
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
157jaundiceFAERS: 2SIDER
US FAERS
158treatment failureFAERS: 2US FAERS
159Accidental exposure to product by childFAERS: 1US FAERS
160Acetonaemic vomitingFAERS: 1US FAERS
161Administration site dischargeFAERS: 1US FAERS
162Adverse eventFAERS: 1US FAERS
163Alanine Aminotransferase IncreasedFAERS: 1SIDER
US FAERS
164Amino acid level increasedFAERS: 1US FAERS
165AmnesiaFAERS: 1OFFSIDES
US FAERS
166AngerFAERS: 1US FAERS
167AnisocytosisFAERS: 1US FAERS
168ApathyFAERS: 1US FAERS
169Aphthous StomatitisFAERS: 1US FAERS
170Apparent deathFAERS: 1US FAERS
171Application site burnFAERS: 1US FAERS
172Application site discomfortFAERS: 1US FAERS
173Application site drynessFAERS: 1US FAERS
174Application site painFAERS: 1US FAERS
175ArteritisFAERS: 1US FAERS
176ArthritisFAERS: 1OFFSIDES
SIDER
US FAERS
177ArthropathyFAERS: 1US FAERS
178AsphyxiaFAERS: 1US FAERS
179AuraFAERS: 1US FAERS
180Bed restFAERS: 1US FAERS
181Biochemical pregnancyFAERS: 1US FAERS
182Blood alkaline phosphatase increasedFAERS: 1US FAERS
183Blood glucose decreasedFAERS: 1US FAERS
184Blood pregnenolone increasedFAERS: 1US FAERS
185Blood pressure fluctuationFAERS: 1US FAERS
186BradyphreniaFAERS: 1US FAERS
187Breast CystFAERS: 1OFFSIDES
US FAERS
188Breast cancer stage IIIFAERS: 1OFFSIDES
US FAERS
189Breast discomfortFAERS: 1SIDER
US FAERS
190Burning sensationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
191Capillary Leak SyndromeFAERS: 1US FAERS
192CataractFAERS: 1OFFSIDES
US FAERS
193Cerebral ThrombosisFAERS: 1SIDER
US FAERS
194Cervical friabilityFAERS: 1US FAERS
195Cervical polypFAERS: 1US FAERS
196Cleft PalateFAERS: 1SIDER
US FAERS
197Coital bleedingFAERS: 1US FAERS
198Cold sweatFAERS: 1OFFSIDES
US FAERS
199Complication of device insertionFAERS: 1US FAERS
200Complications of maternal exposure to therapeutic drugsFAERS: 1US FAERS
201Congenital HypothyroidismFAERS: 1US FAERS
202Consciousness fluctuatingFAERS: 1US FAERS
203Contraindicated product prescribedFAERS: 1US FAERS
204Depressed Level of ConsciousnessFAERS: 1SIDER
US FAERS
205DermatitisFAERS: 1SIDER
US FAERS
206Device malfunctionFAERS: 1US FAERS
207DiplopiaFAERS: 1SIDER
US FAERS
208Drug diversionFAERS: 1US FAERS
209Drug effect incompleteFAERS: 1US FAERS
210Dry skinFAERS: 1US FAERS
211DyspareuniaFAERS: 1SIDER
US FAERS
212DysphoniaFAERS: 1US FAERS
213Ear discomfortFAERS: 1US FAERS
214Economic problemFAERS: 1OFFSIDES
US FAERS
215EczemaFAERS: 1OFFSIDES
US FAERS
216Endometrial thickeningFAERS: 1US FAERS
217Euphoric moodFAERS: 1US FAERS
218Expired drug administeredFAERS: 1US FAERS
219FibromyalgiaFAERS: 1OFFSIDES
US FAERS
220GastritisFAERS: 1SIDER
US FAERS
221General symptomFAERS: 1US FAERS
222Genital rashFAERS: 1US FAERS
223HypervigilanceFAERS: 1US FAERS
224HypoxiaFAERS: 1US FAERS
225Impaired driving abilityFAERS: 1US FAERS
226Inappropriate affectFAERS: 1US FAERS
227Inappropriate schedule of product administrationFAERS: 1US FAERS
228Incorrect dose administered by productFAERS: 1US FAERS
229Incorrect drug administration durationFAERS: 1US FAERS
230Incorrect product storageFAERS: 1US FAERS
231InfertilityFAERS: 1SIDER
US FAERS
232Injection Site ReactionFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
233Injection site extravasationFAERS: 1US FAERS
234Injection site inflammationFAERS: 1US FAERS
235Injection site massFAERS: 1US FAERS
236Insurance issueFAERS: 1US FAERS
237Intentional product misuseFAERS: 1US FAERS
238Intentional product use issueFAERS: 1US FAERS
239Intercepted drug dispensing errorFAERS: 1US FAERS
240Investigation abnormalFAERS: 1US FAERS
241Joint injuryFAERS: 1US FAERS
242LeukocytosisFAERS: 1US FAERS
243Live BirthFAERS: 1
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
244LymphomaFAERS: 1OFFSIDES
US FAERS
245MalabsorptionFAERS: 1US FAERS
246Mastication disorderFAERS: 1
Canada Vigilance: 2		Canada Vigilance
OFFSIDES
US FAERS
247Medical device complicationFAERS: 1US FAERS
248Medication residueFAERS: 1US FAERS
249MenopauseFAERS: 1US FAERS
250MicrocephalyFAERS: 1US FAERS
251Milk soy protein intoleranceFAERS: 1US FAERS
252Musculoskeletal PainFAERS: 1OFFSIDES
SIDER
US FAERS
253NarcolepsyFAERS: 1US FAERS
254No adverse eventFAERS: 1US FAERS
255NoduleFAERS: 1US FAERS
256OligohydramniosFAERS: 1US FAERS
257OnychoclasisFAERS: 1US FAERS
258Oral administration complicationFAERS: 1US FAERS
259Oral painFAERS: 1US FAERS
260Ovarian Hyperstimulation SyndromeFAERS: 1OFFSIDES
SIDER
US FAERS
261OverdoseFAERS: 1US FAERS
262PapuleFAERS: 1US FAERS
263Peripheral swellingFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
264PneumoniaFAERS: 1SIDER
US FAERS
265PoikilocytosisFAERS: 1US FAERS
266PolyhydramniosFAERS: 1US FAERS
267Poor quality drug administeredFAERS: 1US FAERS
268Product coating issueFAERS: 1US FAERS
269Product compounding quality issueFAERS: 1US FAERS
270Product container seal issueFAERS: 1US FAERS
271Product contaminationFAERS: 1US FAERS
272Product contamination physicalFAERS: 1US FAERS
273Product packaging quantity issueFAERS: 1US FAERS
274Product prescribing errorFAERS: 1US FAERS
275Product quality control issueFAERS: 1US FAERS
276Product shape issueFAERS: 1US FAERS
277Product solubility abnormalFAERS: 1US FAERS
278Product tamperingFAERS: 1US FAERS
279PyelonephritisFAERS: 1US FAERS
280Pyogenic granulomaFAERS: 1
Canada Vigilance: 2		Canada Vigilance
US FAERS
281Reaction to azo-dyesFAERS: 1US FAERS
282Reaction to excipientFAERS: 1
Canada Vigilance: 1		Canada Vigilance
US FAERS
283Reaction to preservativesFAERS: 1US FAERS
284Respiratory DepressionFAERS: 1US FAERS
285Respiratory distressFAERS: 1US FAERS
286RestlessnessFAERS: 1US FAERS
287RosaceaFAERS: 1US FAERS
288Secretion dischargeFAERS: 1US FAERS
289Single umbilical arteryFAERS: 1OFFSIDES
US FAERS
290Sinus TachycardiaFAERS: 1US FAERS
291StillbirthFAERS: 1SIDER
US FAERS
292Subcutaneous AbscessFAERS: 1US FAERS
293Suspected counterfeit productFAERS: 1US FAERS
294TachycardiaFAERS: 1SIDER
US FAERS
295ThrombosisFAERS: 1
Canada Vigilance: 1		10911430CTD
SIDER
Canada Vigilance
US FAERS
296Toxicity to various agentsFAERS: 1US FAERS
297Upper respiratory tract congestionFAERS: 1US FAERS
298Urinary Tract PainFAERS: 1US FAERS
299Vaginal erosionFAERS: 1US FAERS
300Vaginal mucosal blisteringFAERS: 1US FAERS
301Vascular purpuraFAERS: 1SIDER
US FAERS
302VasculitisFAERS: 1US FAERS
303Vibratory sense increasedFAERS: 1US FAERS
304Violence-related symptomFAERS: 1US FAERS
305Vitreous DetachmentFAERS: 1OFFSIDES
US FAERS
306Vulvar erosionFAERS: 1US FAERS
307Vulvovaginal burning sensationFAERS: 1
Canada Vigilance: 1		Canada Vigilance
SIDER
US FAERS
308Vulvovaginal drynessFAERS: 1SIDER
US FAERS
309Vulvovaginal erythemaFAERS: 1US FAERS
310Vulvovaginal pruritusFAERS: 1SIDER
US FAERS
311Vulvovaginal rashFAERS: 1US FAERS
312Walking aid userFAERS: 1US FAERS
313Abdominal bloatingSIDER
314Abnormal cervical smearOFFSIDES
315Abnormal visionSIDER
316Abortion, Veterinary18809207CTD
317AbscessOFFSIDES
SIDER
318AcanthosisOFFSIDES
319Acid refluxOFFSIDES
320Actinic keratosisOFFSIDES
321ActinomycosisOFFSIDES
322Adenocarcinoma

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332603
3906481
5556578
20732338
 		CTD
OFFSIDES
323Adenomatous Polyposis ColiOFFSIDES
324Adrenal massOFFSIDES
325AgeusiaOFFSIDES
326AgoraphobiaOFFSIDES
327AlveolitisOFFSIDES
328AmphetaminesOFFSIDES
329Anal abscessOFFSIDES
330Anal discomfortOFFSIDES
331Anaphylactic shockSIDER
332Anaphylactoid ReactionSIDER
333Angina PectorisSIDER
334Angioedemas, Hereditary9538488
19477491		CTD
335AngiomyolipomaOFFSIDES
336AnhedoniaOFFSIDES
337AnhidrosisOFFSIDES
338Anorexia6305905CTD
SIDER
339AnosmiaOFFSIDES
340Anti-thyroid antibody positiveOFFSIDES
341Anticonvulsant drug level decreasedOFFSIDES
342Anticonvulsant toxicityOFFSIDES
343Antimicrobial susceptibility test resistantOFFSIDES
344Anxiety Disorders4806735CTD
345Aortic Valve Stenosis830309CTD
346Aortic valve calcificationOFFSIDES
347AppendectomyOFFSIDES
348Arteriogram coronary abnormalOFFSIDES
349ArthroscopyOFFSIDES
350Aspartate Aminotransferase IncreasedSIDER
351AtaxiaCanada Vigilance: 1Canada Vigilance
352AtelectasisOFFSIDES
353Autonomic neuropathySIDER
354Bacterial disease carrierOFFSIDES
355Basal cell carcinomaOFFSIDES
356BedriddenOFFSIDES
357Bicuspid aortic valveOFFSIDES
358Biliary dilatationOFFSIDES
359Biopsy breast abnormalOFFSIDES
360Biopsy endometrium abnormalOFFSIDES
361BiopsyOFFSIDES
362Bladder painSIDER
363BlepharoptosisOFFSIDES
364Blood and lymphatic system disordersSIDER
365Blood cholesterol abnormalOFFSIDES
366Blood cortisol increasedOFFSIDES
367Blood follicle stimulating hormone abnormalOFFSIDES
368Blood magnesium decreasedOFFSIDES
369Blurred visionOFFSIDES
370Bone density decreasedOFFSIDES
371Bone erosionOFFSIDES
372Bone fragmentationOFFSIDES
373Bone lesionOFFSIDES
374Bone painOFFSIDES
SIDER
375Brain Hemorrhage, Traumatic17868700CTD
376Brain Injuries

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9972699
15380490
15665606
15845082
21549006
 		CTD
377Breast MicrocalcificationOFFSIDES
378Breast cancer recurrentOFFSIDES
379Breast cancer stage IIOFFSIDES
380Breast necrosisOFFSIDES
381BronchiectasisOFFSIDES
382BronchitisSIDER
383Bronchopleural FistulaOFFSIDES
384BursitisOFFSIDES
385Calcium deficiencyOFFSIDES
386Candidiasis of vaginaOFFSIDES
387Carcinoma, Lobular8123867CTD
388Cardiac FlutterOFFSIDES
389Cardioactive drug level increasedOFFSIDES
390Cardiovascular Diseases15352702
16034922		CTD
391Carotid Artery Thrombosis8638876CTD
392Catalepsy2298391CTD
393Cataract operationOFFSIDES
394Caustic injuryOFFSIDES
395Cerebral Hemorrhage8638876CTD
396Cerebral Infarction8638876CTD
397Cerebral artery stenosisOFFSIDES
398Cerebral atrophyOFFSIDES
399Cerebrovascular Disorders9635480CTD
400Cervicobrachial syndromeOFFSIDES
401Chemical and Drug Induced Liver Injury21501669
22157104
24014644		CTD
402Chest wall painOFFSIDES
403ChloasmaSIDER
404Cholelithiasis221871CTD
405Cholestasis9116778CTD
SIDER
406ChondromalaciaOFFSIDES
407ChoreaSIDER
408ChromatopsiaOFFSIDES
409Chronic sinusitisOFFSIDES
410Cocaine-Related Disorders

View details

11900816
12736327
15920500
16160708
17109827
17707520
17924778
17924780
17924781
18067879
18977603
18998113
 		CTD
411CoccidioidomycosisOFFSIDES
412ColitisOFFSIDES
413Colon adenomaOFFSIDES
414Color blindnessOFFSIDES
415Common wartSIDER
416Concomitant disease aggravatedOFFSIDES
417Congenital heart diseaseOFFSIDES
418Congenital tricuspid valve incompetenceOFFSIDES
419ConjunctivitisSIDER
420Contralateral breast cancerOFFSIDES
421Corneal UlcerOFFSIDES
422Cramps of lower extremitiesSIDER
423Creutzfeldt-Jakob diseaseOFFSIDES
424CryptorchidismOFFSIDES
425CyanosisOFFSIDES
426CystitisSIDER
427CystoceleOFFSIDES
428CystOFFSIDES
429Cytomegalovirus antibody positiveOFFSIDES
430DebridementOFFSIDES
431Dementia14558187
16034922
19370593		CTD
432Demyelinating Diseases19031445CTD
433DemyelinationOFFSIDES
434Dental FistulaOFFSIDES
435Depressive disorder4806735
15581673		CTD
436Dermatitis hemorrhagicSIDER
437Diabetic Neuropathies17187935CTD
438Diabetic foot infectionOFFSIDES
439Diastolic dysfunctionOFFSIDES
440Disease ProgressionOFFSIDES
441Disorders of Sex Development5408743
22238285		CTD
442Disseminated Intravascular Coagulation65916CTD
443Disturbance in sexual arousalSIDER
444DiverticulitisOFFSIDES
445DiverticulosisOFFSIDES
446DiverticulumOFFSIDES
447DrowsinessOFFSIDES
SIDER
448Drug exposure before pregnancyOFFSIDES
449Duodenogastric RefluxOFFSIDES
450Dyskinesia, Drug-Induced17988775CTD
451DysmenorrheaOFFSIDES
452DysuriaSIDER
453Ear and labyrinth disordersSIDER
454Electrocardiogram repolarisation abnormalityOFFSIDES
455EmbolismOFFSIDES
SIDER
456Embryo Loss21540246
23409146		CTD
457Emotional distressOFFSIDES
458EmpyemaOFFSIDES
459Endodontic procedureOFFSIDES
460Endometrial Neoplasms

View details

332603
2531993
3906481
22543862
 		CTD
461Endometrial hypertrophyOFFSIDES
462Endometriosis

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8529825
16134523
20864642
23284138
 		CTD
SIDER
463EructationSIDER
464Erythema MultiformeSIDER
465Erythema NodosumSIDER
466Esophageal StenosisOFFSIDES
467Essential HypertensionOFFSIDES
468Ethmoid sinus surgeryOFFSIDES
469Eustachian tube disorderOFFSIDES
470Exacerbation of asthmaSIDER
471ExcoriationOFFSIDES
472Eye laser surgeryOFFSIDES
473Fat necrosisOFFSIDES
474Fatty LiverOFFSIDES
475Female sexual arousal disorderOFFSIDES
476FertilizationSIDER
477Fetal Death65916CTD
478Fibroadenoma of breastOFFSIDES
479Flank PainOFFSIDES
480Fluid overloadOFFSIDES
481Food PoisoningOFFSIDES
482FormicationOFFSIDES
483Gamma-Glutamyltransferase IncreasedSIDER
484GastroenteritisCanada Vigilance: 1Canada Vigilance
OFFSIDES
SIDER
485Gastrointestinal PainSIDER
486Gestational DiabetesOFFSIDES
487Gingival graftOFFSIDES
488Gliosis19031445CTD
489Gonadal Dysgenesis2673747CTD
490Hay feverOFFSIDES
491Hepatic necrosisSIDER
492Hepatitis B antibody positiveOFFSIDES
493Hepatitis B positiveOFFSIDES
494HepatitisSIDER
495HepatosplenomegalyOFFSIDES
496HepatotoxicityOFFSIDES
497HirsutismSIDER
498HydrometraOFFSIDES
499HydronephrosisOFFSIDES
500HydropneumothoraxOFFSIDES
501Hypercholesterolemia2673747CTD
502HyperkeratosisOFFSIDES
503Hyperprolactinemia

View details

2105248
2656304
3346359
3964786
7962471
 		CTD
504Hypertrophy18845635CTD
505HyperventilationSIDER
506HypophagiaOFFSIDES
507Hypopituitarism2673747CTD
508HysterectomyOFFSIDES
509IncontinenceOFFSIDES
510Infarction, Middle Cerebral Artery15869954
21277368		CTD
511InfestationSIDER
512Influenza-like symptomsSIDER
513Injection site burningOFFSIDES
514Injection site dermatitisOFFSIDES
515Injection site irritationOFFSIDES
516Injection site phlebitisOFFSIDES
517Injection site warmthOFFSIDES
518Injury associated with deviceCanada Vigilance: 1Canada Vigilance
519Intervertebral Disc DegenerationOFFSIDES
520Intervertebral disc disorderOFFSIDES
521Intestinal ObstructionCanada Vigilance: 1Canada Vigilance
522IritisOFFSIDES
523KeratomileusisOFFSIDES
524Kidney Diseases6305905CTD
525LacerationOFFSIDES
526Lesion excisionOFFSIDES
527LeukorrheaSIDER
528LightheadednessSIDER
529Lipoma of breastOFFSIDES
530Liver Cirrhosis, Experimental1465320
6462789
8170719		CTD
531Loose toothOFFSIDES
532Low turnover osteopathyOFFSIDES
533Lumbar radiculopathyOFFSIDES
534Lung InjuryOFFSIDES
535LymphadenopathySIDER
536LymphedemaOFFSIDES
537Lymphocyte count decreasedOFFSIDES
538MacrocytosisOFFSIDES
539Malignant neoplasm of ampulla of VaterOFFSIDES
540MalnutritionSIDER
541MalocclusionOFFSIDES
542Mammary Neoplasms, Experimental11408345
17203775		CTD
543MassageOFFSIDES
544MastectomyOFFSIDES
545Mastitis2275290CTD
546Mastodynia2275290CTD
547MastoiditisOFFSIDES
548Mediastinal massOFFSIDES
549Melanoma recurrentOFFSIDES
550Mental disorders8724175CTD
551Metabolic acidosisOFFSIDES
552MetamorphopsiaOFFSIDES
553MetaplasiaOFFSIDES
554Mitochondrial Diseases22486171CTD
555Mitral Valve StenosisOFFSIDES
556Mitral valve sclerosisOFFSIDES
557MoaningOFFSIDES
558Modified radical mastectomyOFFSIDES
559Molluscum ContagiosumOFFSIDES
560MononeuritisOFFSIDES
561Motor Neuron Disease22486171CTD
562Multiple MyelomaOFFSIDES
563Multiple PregnancyOFFSIDES
564Muscle WeaknessOFFSIDES
565Muscle flap operationOFFSIDES
566Musculoskeletal chest painOFFSIDES
567Musculoskeletal discomfortSIDER
568Myasthenic SyndromeOFFSIDES
569MyopathySIDER
570Myositis3342908CTD
571NasopharyngitisOFFSIDES
SIDER
572Nerve Degeneration19497309
19693665
19840816		CTD
573Neurasthenia4806735CTD
574NeuritisSIDER
575NeurodermatitisOFFSIDES
576Neurotoxicity Syndromes19497309CTD
577No reaction on previous exposure to drugOFFSIDES
578NocturiaSIDER
579Nodule on extremityOFFSIDES
580Non-cardiac chest painOFFSIDES
581ObstructionOFFSIDES
582Occult blood positiveOFFSIDES
583Optic AtrophyOFFSIDES
584Optic NeuritisOFFSIDES
SIDER
585Oral Cavity FistulaOFFSIDES
586Oral mucosa atrophyOFFSIDES
587Oral pruritusOFFSIDES
588Oroantral FistulaOFFSIDES
589Oropharyngeal blisteringOFFSIDES
590OrthopneaOFFSIDES
591OsteolysisOFFSIDES
592OsteomaOFFSIDES
593OsteopeniaOFFSIDES
594OsteoporosisOFFSIDES
595OsteoradionecrosisOFFSIDES
596Ovarian Cysts21239663CTD
597Ovarian enlargementOFFSIDES
598Ovarian failureSIDER
599Oxygen supplementationOFFSIDES
600PO2 decreasedOFFSIDES
601Panic Disorder15996752CTD
602PanniculitisOFFSIDES
603Patent ductus arteriosusSIDER
604Pelvic fluid collectionOFFSIDES
605Pelvic venous thrombosisSIDER
606Pericardial effusionOFFSIDES
607Perineal painSIDER
608Peripheral Nervous System Diseases19335538CTD
609Peroneal nerve injuryOFFSIDES
610Pharyngeal swellingCanada Vigilance: 1Canada Vigilance
611PharyngitisSIDER
612Pigmentary retinopathyOFFSIDES
613Pilonidal cyst congenitalOFFSIDES
614PingueculaOFFSIDES
615PlasmacytosisOFFSIDES
616PlatybasiaOFFSIDES
617PleurisyOFFSIDES
618Polycystic Ovary Syndrome21411543CTD
619PolyuriaOFFSIDES
620Poor peripheral circulationOFFSIDES
621Post procedural cellulitisOFFSIDES
622Post procedural fistulaOFFSIDES
623Posterior CapsulotomyOFFSIDES
624Postmenopausal bleedingOFFSIDES
625Postoperative abscessOFFSIDES
626Postoperative ileusOFFSIDES
627Pre-EclampsiaOFFSIDES
628Pregnancy Complications9116778CTD
629Pregnancy test negativeCanada Vigilance: 1Canada Vigilance
630Pregnancy test positiveOFFSIDES
631Premature Birth14672496
18712170		CTD
632Premenstrual TensionSIDER
633Premenstrual syndromeSIDER
634Procedural complicationOFFSIDES
635Product administration errorCanada Vigilance: 1Canada Vigilance
636Product dose omissionCanada Vigilance: 2Canada Vigilance
637Product residue presentCanada Vigilance: 1Canada Vigilance
638Progesterone receptor assayOFFSIDES
639Progressive supranuclear palsyOFFSIDES
640Protein S abnormalOFFSIDES
641Psychiatric symptomOFFSIDES
642Pulmonary toxicityOFFSIDES
643PurpuraSIDER
644Purulent dischargeOFFSIDES
645PyeloplastyOFFSIDES
646Radiation associated painOFFSIDES
647Radiation skin injuryOFFSIDES
648Rectal polypOFFSIDES
649Rectal tenesmusOFFSIDES
650RectoceleOFFSIDES
651RednessSIDER
652Regurgitation of foodOFFSIDES
653Renal ColicOFFSIDES
654Renal cystOFFSIDES
655Retained products of conceptionOFFSIDES
656Retinal Vein OcclusionOFFSIDES
657Retinal migraineOFFSIDES
658RhinalgiaOFFSIDES
659RhinitisSIDER
660RhinorrheaOFFSIDES
661Ruptured ectopic pregnancyOFFSIDES
662Salivary Gland Neoplasms18045962CTD
663Schizoaffective DisorderOFFSIDES
664Seizures

View details

7710963
9757004
9972699
10725616
12601707
19840816
20801149
 		CTD
665SepsisCanada Vigilance: 1Canada Vigilance
666ShockSIDER
667Sinus Thrombosis, Intracranial8638876CTD
668Sinus antrostomyOFFSIDES
669Sinus operationOFFSIDES
670SinusitisOFFSIDES
SIDER
671Skeletal injuryOFFSIDES
672Skin PapillomaSIDER
673Skin neoplasm excisionOFFSIDES
674Sleep TalkingOFFSIDES
675Slurred speechSIDER
676Spinal Cord Injuries15862959
16503802		CTD
677Spinal column stenosisOFFSIDES
678Spinal fusion surgeryOFFSIDES
679Splenic vein thrombosisOFFSIDES
680Sputum culture positiveOFFSIDES
681Status Epilepticus16084511CTD
682Stem cell transplantCanada Vigilance: 1Canada Vigilance
OFFSIDES
683StuporSIDER
684Subcutaneous noduleOFFSIDES
685Substance Withdrawal Syndrome7710963
9757004
10690749		CTD
686TendinitisOFFSIDES
687TenosynovitisOFFSIDES
688TensionSIDER
689TetanyOFFSIDES
690Therapeutic procedureOFFSIDES
691ThirstSIDER
692ThoracotomyOFFSIDES
693ThromboembolismSIDER
694ThrombophlebitisSIDER
695Thrombosis in deviceOFFSIDES
696TonsillitisOFFSIDES
697Tooth InfectionOFFSIDES
698Tooth LossOFFSIDES
699ToothacheSIDER
700Transaminases increasedSIDER
701Trisomy 21OFFSIDES
702Troponin I increasedOFFSIDES
703Ultrasound biliary tractOFFSIDES
704Ultrasound breast abnormalOFFSIDES
705Ultrasound uterus abnormalOFFSIDES
706Uterine Diseases18845635CTD
707Uterine ProlapseOFFSIDES
708Uterine cervix stenosisOFFSIDES
709VIIth nerve paralysisOFFSIDES
710Vaginal Neoplasms5556578CTD
711Vaginal burning sensationSIDER
712Vaginal drynessSIDER
713Vaginal irritationSIDER
714Vaginal mycosisSIDER
715Vascular calcificationOFFSIDES
716Venous InsufficiencyOFFSIDES
717Venous Thromboembolism16034922
18599555
19370593		CTD
718Venous Thrombosis9635480
10911430		CTD
719Visual disturbanceOFFSIDES
SIDER
720VitrectomyOFFSIDES
721Vulvovaginal injuryCanada Vigilance: 1Canada Vigilance
722Vulvovaginal mycotic infectionSIDER
723Wound dehiscenceOFFSIDES
724Wound infection staphylococcalOFFSIDES
725Wound necrosisOFFSIDES
726XerophthalmiaSIDER
727colonoscopyOFFSIDES
728fibromaOFFSIDES
729muscle injuryOFFSIDES
730nervous system disorderSIDER
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