MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Rheumatoid Vasculitis

(UMLS:C0240903)

Definition:: Necrotizing VASCULITIS of small and medium size vessels, developing as a complication in RHEUMATOID ARTHRITIS patients. It is characterized by peripheral vascular lesions, cutaneous ULCERS, peripheral GANGRENE, and MONONEURITIS MULTIPLEX.
UMLS ID:: C0240903
MeSH ID:: D056653

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.550.114.154.728|C05.799.114.728

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.940.897.750

Classification 3:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.775.099.728

Classification 4:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.111.199.581

Synonym(s)

Rheumatoid Vasculitis

Rheumatoid vasculitis

arthritis; rheumatoid, with vasculitis

rheumatoid vasculitis

rheumatoid; arthritis, with vasculitis

rheumatoid; vasculitis

vasculitis rheumatoid

vasculitis; rheumatoid

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Leflunomide	FAERS: 1		OFFSIDES US FAERS
2	Methotrexate	FAERS: 1		US FAERS
3	Methotrexate	FAERS: 1		US FAERS
4	Sitagliptin Phosphate	FAERS: 1		US FAERS
5	baricitinib	FAERS: 1		US FAERS
6	eribulin	FAERS: 1		US FAERS
7	sibutramine	FAERS: 1		US FAERS
8	tofacitinib	FAERS: 1		US FAERS
9	Bromhexine			OFFSIDES
10	Cyclophosphamide		14691658	CTD
11	Etoricoxib			OFFSIDES
12	Prednisone acetate			OFFSIDES
13	acetaminophen, dextropropoxyphene, drug combination			OFFSIDES
14	strontium ranelate			OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Felty Syndrome	44.4%
2	Rheumatoid Nodule	38.4%
3	Sicca Syndrome	36.3%
4	Sjogren's Syndrome	36.3%
5	Juvenile arthritis	32.3%
6	Polymyalgia Rheumatica	23%
7	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	22.6%
8	Gout	20.1%
9	Rheumatic Fever	19.8%
10	Polyarteritis Nodosa	19.2%
11	Osteoarthritis, Spine	19.2%
12	Periarthritis	17.8%
13	Cartilage Diseases	16.6%
14	Chondromalacia	16.6%
15	Arthrogryposis	16.1%
16	Lupus Erythematosus, Systemic	15.8%
17	Overlap syndrome	15.8%
18	Arthritis, Psoriatic	15.7%
19	Contracture	15.3%
20	Osteoarthropathy, Secondary Hypertrophic	15.3%
21	Osteoarthritis, Knee	15%
22	Fibromyalgia	14.2%
23	Granulomatosis with polyangiitis	14.1%
24	Aortitis	14.1%
25	Periphlebitis	14.1%
26	Phlebitis	14.1%
27	Thromboangiitis Obliterans	14.1%
28	Vasculitis, Central Nervous System	13.9%
29	Sacroiliitis	13.7%
30	Malignant Atrophic Papulosis	13.6%
31	Metatarsalgia	13.3%
32	Arthritis, Gouty	13.3%
33	Ischemic contracture	13.2%
34	Osteochondritis	13%
35	Pectus carinatum	12.7%
36	Giant Cell Arteritis	12.5%
37	Temporal Arteritis	12.5%
38	Compartment syndromes	12.4%
39	Shwartzman Phenomenon	12.3%
40	Arthritis, Reactive	12.1%
41	Ankylosing spondylitis	12%
42	Arthritis, Infectious	11.8%
43	Vasculitis, Leukocytoclastic, Cutaneous	11.7%
44	Arthritis, Experimental	11.7%
45	Foot Diseases	11.7%
46	Bursitis	11.6%
47	Joint Instability	11.6%
48	Synovitis	11.6%
49	Joint laxity	11.6%
50	Frozen shoulder	11.6%
51	Patellofemoral Pain Syndrome	11.6%
52	Arteritis	11.5%
53	Temporomandibular Joint Disorders	11.1%
54	Bone Diseases	10.7%
55	Fasciitis	10.7%
56	Foot Deformities	10.7%
57	Fasciitis, Plantar	10.5%
58	Lupus Vasculitis, Central Nervous System	10.2%
59	Dermatitis Herpetiformis	10%
60	Mucocutaneous Lymph Node Syndrome	10%
61	Hemarthrosis	10%
62	Pemphigus	10%
63	Retinal Vasculitis	10%
64	Antiphospholipid Syndrome	9.9%
65	Thrombophlebitis	9.9%
66	Spondylarthropathies	9.7%
67	Lupus Erythematosus, Cutaneous	9.6%
68	Panniculitis	9.6%
69	Systemic Scleroderma	9.6%
70	Myocardial Ischemia	9.6%
71	Morphea	9.6%
72	Tietze's Syndrome	9.5%
73	Jaw Diseases	9.5%
74	Hip Contracture	9.4%
75	Takayasu Arteritis	9.4%
76	Myopathy	9.3%
77	Dermatomyositis	9.2%
78	Dupuytren Contracture	9.1%
79	Nail-Patella Syndrome	8.9%
80	Temporomandibular Joint Dysfunction Syndrome	8.7%
81	Addison Disease	8.5%
82	Autoimmune thyroiditis	8.5%
83	Primary Adrenal Insufficiency	8.5%
84	Autoimmune hepatitis	8.5%
85	Aortic Aneurysm	8.5%
86	Leriche Syndrome	8.5%
87	Noonan Syndrome	8.4%
88	Aneurysm	8.3%
89	Angiomatosis	8.3%
90	Aortic Diseases	8.3%
91	Arterial Occlusive Diseases	8.3%
92	Collagen Diseases	8.3%
93	Hyperemia	8.3%
94	Hypotension	8.3%
95	Mixed Connective Tissue Disease	8.3%
96	Pseudoxanthoma Elasticum	8.3%
97	Superior Vena Cava Syndrome	8.3%
98	Telangiectasis	8.3%
99	Venous Insufficiency	8.3%
100	Peripheral Vascular Diseases	8.3%
101	Embolism and Thrombosis	8.3%
102	Angiodysplasia	8.3%
103	Mucinoses	8.3%
104	Capillary Leak Syndrome	8.3%
105	Prehypertension	8.3%
106	Angioedema	8.2%
107	Autoimmune Lymphoproliferative Syndrome	8.2%
108	Retinal Vein Occlusion	8.1%
109	Myocardial Reperfusion Injury	7.9%
110	Behcet Syndrome	7.8%
111	Marfan Syndrome	7.8%
112	Arthralgia	7.7%
113	Platybasia	7.7%
114	Polyarthralgia	7.7%
115	Endarteritis	7.6%
116	Lupus Nephritis	7.6%
117	Anterior Compartment Syndrome	7.5%
118	Abdominal Compartment Syndrome	7.5%
119	Latent Autoimmune Diabetes in Adults	7.5%
120	Cutis Laxa	7.5%
121	Pectus excavatum	7.5%
122	Kounis Syndrome	7.5%
123	Vascular System Injuries	7.3%
124	Panniculitis, Lupus Erythematosus	7.3%
125	Hepatic Veno-Occlusive Disease	7.2%
126	Peliosis Hepatis	7.2%
127	Varicocele	7.2%
128	Cerebrovascular Disorders	7.1%
129	Diabetic Angiopathies	7.1%
130	Reperfusion Injury	7.1%
131	Splenic Infarction	7.1%
132	Cerebrovascular Insufficiency	7.1%
133	Vascular Neoplasms	7.1%
134	Spinal Cord Vascular Diseases	7.1%
135	Vasoplegia	7.1%
136	Hemorrhoids	7.1%
137	Thoracic Outlet Syndrome	7.1%
138	Postphlebitic Syndrome	7%
139	Coronary Aneurysm	6.9%
140	CREST Syndrome	6.8%
141	Laryngomalacia	6.7%
142	Graves Disease	6.6%
143	Klippel-Feil Syndrome	6.6%
144	Synostosis	6.6%
145	Autoimmune thrombocytopenia	6.6%
146	Immune thrombocytopenic purpura	6.6%
147	Aortic Rupture	6.6%
148	Anti-Glomerular Basement Membrane Disease	6.6%
149	Arteriovenous fistula	6.5%
150	Talipes	6.5%
151	Hand-Arm Vibration Syndrome	6.4%
152	Moyamoya Disease	6.3%
153	Optic Neuropathy, Ischemic	6.3%
154	Anterior Ischemic Optic Neuropathy	6.3%
155	Mesenteric vascular insufficiency	6.3%
156	Colitis, Ischemic	6.2%
157	Intracranial Embolism and Thrombosis	6.1%
158	Carotid Stenosis	6.1%
159	Intracranial Aneurysm	6.1%
160	Bone Diseases, Developmental	6.1%
161	Hyperostosis	6.1%
162	Myofascial Pain Syndromes	6.1%
163	Osteitis	6.1%
164	Osteitis Deformans	6.1%
165	Osteochondrosis	6.1%
166	Rhabdomyolysis	6.1%
167	Spinal Diseases	6.1%
168	Blue Toe Syndrome	5.9%
169	Carotid Artery Thrombosis	5.9%
170	Craniosynostosis	5.9%
171	Syndactyly	5.9%
172	Brachycephaly	5.9%
173	Acrocephalosyndactylia	5.8%
174	Osteogenesis Imperfecta	5.8%
175	Gigantism	5.8%
176	Spinal Neoplasms	5.8%
177	Spondylitis	5.8%
178	Coronary Thrombosis	5.7%
179	Coronary Artery Disease	5.7%
180	Hypersensitivity	5.6%
181	Immunologic Deficiency Syndromes	5.6%
182	Immunoproliferative Disorders	5.6%
183	Arthropathy	5.6%
184	Immune reconstitution syndrome	5.6%
185	Immune Reconstitution Inflammatory Syndrome	5.6%
186	Coronary heart disease	5.6%
187	Lupus Erythematosus, Discoid	5.6%
188	Myocardial Infarction	5.6%
189	Scleroderma, Limited	5.6%
190	Acute Coronary Syndrome	5.6%
191	Lemierre Syndrome	5.6%
192	Aortic Aneurysm, Abdominal	5.6%
193	Aortic Aneurysm, Thoracic	5.6%
194	Cellulitis	5.5%
195	Scimitar Syndrome	5.5%
196	Hip Dislocation	5.4%
197	Shoulder Dislocation	5.4%
198	Hip Dysplasia	5.4%
199	Bone Diseases, Endocrine	5.4%
200	Myasthenia Gravis, Autoimmune, Experimental	5.3%
201	Bone Diseases, Infectious	5.3%
202	Bone neoplasms	5.3%
203	Maxillary Diseases	5.3%
204	Osteopenia	5.3%
205	Tendinitis	5.3%
206	Tendinopathy	5.3%
207	Bone Resorption	5.2%
208	Myositis	5.2%
209	Limb Deformities, Congenital	5.2%
210	Isaacs syndrome	5.2%
211	Craniofacial Abnormalities	5.2%
212	Aseptic Necrosis of Bone	5.2%
213	Myotonic Disorders	5.2%
214	Varicose Ulcer	5.1%
215	Heart Diseases	5.1%
216	Multiple Myeloma	5.1%
217	Myasthenia Gravis	5%
218	Uveomeningoencephalitic Syndrome	5%
219	Livedo Reticularis	4.9%
220	Aneurysm, Dissecting	4.9%
221	Arteriosclerosis	4.9%
222	Embolism	4.9%
223	Erythromelalgia	4.9%
224	Fibromuscular Dysplasia	4.9%
225	Malignant Hypertension	4.9%
226	Raynaud Disease	4.9%
227	Thromboembolism	4.9%
228	Thrombosis	4.9%
229	Essential Hypertension	4.9%
230	Aneurysm, Ruptured	4.9%
231	Iliac Aneurysm	4.9%
232	Pulmonary artery stenosis	4.9%
233	White Coat Hypertension	4.9%
234	Scleromyxedema	4.9%
235	Embolus	4.9%
236	May-Thurner Syndrome	4.9%
237	Angina Pectoris	4.9%
238	Craniofacial Dysostosis	4.9%
239	Transfusion Reaction	4.9%
240	Hypotensive Transfusion Reaction	4.9%
241	Intracranial Arteriosclerosis	4.9%
242	Cerebral Atherosclerosis	4.9%
243	Cerebral Arteriosclerosis	4.9%
244	Congenital clubfoot	4.8%
245	Vertical Talus	4.8%
246	Jaw Abnormalities	4.8%
247	Angioedemas, Hereditary	4.7%
248	Cryoglobulinemia	4.7%
249	Bronchomalacia	4.7%
250	Tracheomalacia	4.7%
251	Shoulder Pain	4.7%
252	Medial Tibial Stress Syndrome	4.6%
253	Mitochondrial Myopathies	4.6%
254	Embolism, Amniotic Fluid	4.5%
255	Muscle Cramp	4.5%
256	Eosinophilia-Myalgia Syndrome	4.5%
257	Gastroschisis	4.5%
258	Muscle Rigidity	4.5%
259	Muscle Spasticity	4.5%
260	Cogwheel Rigidity	4.5%
261	Nuchal Rigidity	4.5%
262	Prognathism	4.5%
263	Erythema Induratum	4.5%
264	Stiff-Person Syndrome	4.5%
265	Polyradiculoneuropathy	4.4%
266	Polyradiculoneuritis	4.4%
267	Pregnancy Complications, Cardiovascular	4.4%
268	Rheumatism	4.4%
269	Cardiovascular Abnormalities	4.4%
270	Necrobiosis Lipoidica Diabeticorum	4.4%
271	Poland Syndrome	4.4%
272	Brain Infarction	4.3%
273	Dermatitis, Atopic	4.3%
274	Mesenteric Panniculitis	4.3%
275	Panniculitis, Peritoneal	4.3%
276	Retinal Artery Occlusion	4.3%
277	Orbital Cellulitis	4.3%
278	Hypertensive Retinopathy	4.3%
279	Myxoid cyst	4.3%
280	Cerebral Thrombosis	4.3%
281	Intracranial Embolism	4.3%
282	Intracranial Thrombosis	4.3%
283	Myxedema	4.2%
284	Gastric Antral Vascular Ectasia	4.2%
285	Carotid Artery Diseases	4.2%
286	Brain Ischemia	4.2%
287	Hypotension, Orthostatic	4.2%
288	Cerebrovascular accident	4.2%
289	Vasospasm, Intracranial	4.2%
290	Spinal Cord Ischemia	4.2%
291	Intracranial Arterial Diseases	4.2%
292	Primary Graft Dysfunction	4.2%
293	Post-Exercise Hypotension	4.2%
294	Chronic Fatigue Syndrome	4.2%
295	Glomerulonephritis, Membranoproliferative	4.2%
296	Ataxia Telangiectasia	4.2%
297	Neuromyelitis Optica	4.1%
298	Leukoencephalitis, Acute Hemorrhagic	4.1%
299	Giant Cell Epulis	4.1%
300	Muscle Weakness	4.1%
301	Homocystinuria	4.1%
302	Discitis	4.1%
303	Musculoskeletal Pain	4%
304	Familial Periodic Paralysis	4%
305	Subarachnoid Hemorrhage, Traumatic	4%
306	Carotid Artery, Internal, Dissection	4%
307	Congenital Hypothyroidism	4%
308	Vertebral Artery Dissection	3.9%
309	Waldenstrom Macroglobulinemia	3.9%
310	Hereditary Angioedema Type III	3.8%
311	Hereditary Angioedema Types I and II	3.8%
312	Ainhum	3.8%
313	Bunion	3.8%
314	Dysostoses	3.8%
315	Fibrodysplasia Ossificans Progressiva	3.8%
316	Myoglobinuria	3.8%
317	Myositis Ossificans	3.8%
318	Spinal Stenosis	3.8%
319	Spondylosis	3.8%
320	Tenosynovitis	3.8%
321	Intervertebral Disc Degeneration	3.8%
322	Diabetic Foot	3.8%
323	Mesenteric Vascular Occlusion	3.7%
324	Coronary Occlusion	3.7%
325	Microvascular Angina	3.7%
326	Coronary Stenosis	3.7%
327	ST segment elevation myocardial infarction	3.7%
328	Diabetic Retinopathy	3.7%
329	Mastocytosis	3.7%
330	Sturge-Weber Syndrome	3.7%
331	Pyoderma Gangrenosum	3.7%
332	Renal hypertension	3.7%
333	Multiple Sclerosis	3.7%
334	Renal Artery Obstruction	3.7%
335	Renal Artery Stenosis	3.7%
336	Granuloma Annulare	3.7%
337	Hemangioma, Cavernous	3.7%
338	Keloid	3.7%
339	Basal Ganglia Cerebrovascular Disease	3.7%
340	Vascular Headaches	3.7%
341	Scurvy	3.7%
342	Eosinophilic Granuloma	3.6%
343	Lambert-Eaton Myasthenic Syndrome	3.6%
344	Myalgia	3.6%
345	Tuberculosis, Spinal	3.6%
346	Antley-Bixler Syndrome Phenotype	3.6%
347	Carotid Artery Injuries	3.6%
348	Infarction, Middle Cerebral Artery	3.5%
349	Infarction, Anterior Cerebral Artery	3.5%
350	Infarction, Posterior Cerebral Artery	3.5%
351	Rheumatoid Arthritis	3.3%
352	Sinus Thrombosis, Intracranial	3.3%
353	Multiple Epiphyseal Dysplasia	3.3%
354	Osteochondrodysplasias	3.3%
355	Thrombocytopenic purpura	3.3%
356	Arthritis	3.3%
357	Immune Complex Diseases	3.3%
358	Polyarthritis	3.3%
359	Latex allergy	3.3%
360	Osteomyelitis	3.3%
361	Osteoporosis	3.3%
362	Periostitis	3.3%
363	Urticaria	3.3%
364	Enthesopathy	3.3%
365	Bone Demineralization, Pathologic	3.3%
366	Post-Traumatic Osteoporosis	3.3%
367	Tricuspid Atresia	3.3%
368	Arrhythmogenic Right Ventricular Dysplasia	3.3%
369	Rubinstein-Taybi Syndrome	3.3%
370	Myotonic Dystrophy	3.3%
371	Leukomalacia, Periventricular	3.3%
372	Alveolar Bone Loss	3.3%
373	Amelia	3.3%
374	Arachnodactyly	3.3%
375	Ectromelia	3.3%
376	Femur Head Necrosis	3.3%
377	Hemimelia	3.3%
378	Phocomelia	3.3%
379	Sirenomelia	3.3%
380	Polymyositis	3.3%
381	Polydactyly	3.3%
382	Brachydactyly	3.3%
383	Plagiocephaly	3.3%
384	Lower Extremity Deformities, Congenital	3.3%
385	Upper Extremity Deformities, Congenital	3.3%
386	Osteolysis	3.3%
387	Encephalomyelitis, Acute Disseminated	3.3%
388	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	3.3%
389	Shock, Cardiogenic	3.3%
390	Dermatitis, Allergic Contact	3.3%
391	Palatal Neoplasms	3.3%
392	Arteriosclerosis Obliterans	3.3%
393	Atherosclerosis	3.3%
394	Air Embolism	3.3%
395	Neuritis, Autoimmune, Experimental	3.3%
396	Serum Sickness	3.3%
397	Venous Thrombosis	3.3%
398	Deep Vein Thrombosis	3.3%
399	Venous Thromboembolism	3.3%
400	Dermatitis, Photoallergic	3.2%
401	Mandibulofacial Dysostosis	3.2%
402	Micrognathism	3.2%
403	Pierre Robin Syndrome	3.2%
404	Angina, Unstable	3.2%
405	Cerebral Infarction	3.2%
406	Brain Stem Infarctions	3.2%
407	Basal Ganglia Hemorrhage	3.1%
408	Xeroderma Pigmentosum	3.1%
409	Multiple Sclerosis, Chronic Progressive	3%
410	Multiple Sclerosis, Relapsing-Remitting	3%
411	Goldenhar Syndrome	3%
412	Retrognathia	3%
413	Dwarfism	3%
414	Bacterial Endocarditis	3%
415	Epidermolysis Bullosa	3%
416	Guillain-Barre Syndrome	2.9%
417	Shy-Drager Syndrome	2.9%
418	Purpura, Hyperglobulinemic	2.9%
419	Environmental Illness	2.9%
420	Primary amyloidosis	2.9%
421	Monoclonal Gammopathy of Undetermined Significance	2.9%
422	Erythema Nodosum	2.9%
423	Muscular Dystrophy	2.9%
424	Orbital Myositis	2.9%
425	Drug Eruptions	2.9%
426	Lymphoproliferative Disorders	2.9%
427	Pyomyositis	2.9%
428	Cavernous Sinus Thrombosis	2.9%
429	Sagittal Sinus Thrombosis	2.9%
430	Acromegaly	2.9%
431	Joint Tuberculosis	2.9%
432	Tuberculosis, Osteoarticular	2.9%
433	Bone Tuberculosis	2.9%
434	Paraproteinemias	2.8%
435	Intermittent Claudication	2.8%
436	Lymphopenia	2.8%
437	Pulmonary Embolism	2.8%
438	Acne Vulgaris	2.8%
439	Aortic Valve Stenosis	2.8%
440	Cardiomyopathy, Dilated	2.8%
441	Contact Dermatitis	2.8%
442	Eczema	2.8%
443	Erythema Multiforme	2.8%
444	Intertrigo	2.8%
445	Neurodermatitis	2.8%
446	Pulmonary Valve Stenosis	2.8%
447	Rhinophyma	2.8%
448	Perioral Dermatitis	2.8%
449	Acne	2.8%
450	Basal Cell Nevus Syndrome	2.8%
451	No-Reflow Phenomenon	2.8%
452	Cerebral Arterial Diseases	2.8%
453	Vertebrobasilar Insufficiency	2.8%
454	Anterior Spinal Artery Syndrome	2.8%
455	Basilar Artery Stenosis	2.8%
456	Vertebral Artery Stenosis	2.8%
457	Intracranial Hemorrhage, Hypertensive	2.8%
458	Transient Cerebral Ischemia	2.8%
459	Coronary Restenosis	2.8%
460	Breast Diseases	2.8%
461	Cardiac Tamponade	2.8%
462	Dermatitis	2.8%
463	Endocarditis	2.8%
464	Exanthema	2.8%
465	Facial Dermatoses	2.8%
466	Hair Diseases	2.8%
467	Hand Dermatoses	2.8%
468	Cardiac Arrest	2.8%
469	Heart failure	2.8%
470	keratoacanthoma	2.8%
471	Keratosis	2.8%
472	Nail Diseases	2.8%
473	Pericardial effusion	2.8%
474	Pericarditis	2.8%
475	Photosensitivity Disorders	2.8%
476	Pneumopericardium	2.8%
477	Prurigo	2.8%
478	Cor pulmonale	2.8%
479	Pyoderma	2.8%
480	Rosacea	2.8%
481	Sebaceous Gland Diseases	2.8%
482	Skin Diseases, Vesiculobullous	2.8%
483	Skin Ulcer	2.8%
484	Sweat Gland Diseases	2.8%
485	Ventricular Outflow Obstruction	2.8%
486	Skin Diseases, Papulosquamous	2.8%
487	Skin Diseases, Vascular	2.8%
488	Acneiform Eruptions	2.8%
489	Ventricular Dysfunction	2.8%
490	Ocular Rosacea	2.8%
491	Subcorneal pustular dermatosis	2.8%
492	Cardiomyopathies	2.8%
493	Pleuropericarditis	2.8%
494	Erythematotelangiectatic Rosacea	2.8%
495	Papulopustular Rosacea	2.8%
496	Chronic Actinic Dermatitis	2.8%
497	Chondrodysplasia Punctata	2.7%
498	Enchondromatosis	2.7%
499	Lordosis	2.7%
500	Osteosclerosis	2.7%
501	Spondylolysis	2.7%
502	kyphosis	2.7%
503	Kashin-Beck Disease	2.7%
504	Lateral Medullary Syndrome	2.7%
505	Toxic Epidermal Necrolysis	2.7%
506	Stevens-Johnson Syndrome	2.7%
507	Asthma, Aspirin-Induced	2.6%
508	Maxillofacial Abnormalities	2.6%
509	Cleft Palate	2.6%
510	Myotonia Congenita	2.6%
511	Rickets	2.5%
512	MELAS Syndrome	2.5%
513	Microcephaly	2.5%
514	Macrocephaly	2.5%
515	Hypokalemic periodic paralysis	2.5%
516	Hypergammaglobulinemia	2.5%
517	Agammaglobulinemia	2.5%
518	HIV Infections	2.5%
519	Transfusion-Related Acute Lung Injury	2.5%
520	Acrodermatitis	2.5%
521	Heart Block	2.5%
522	Sebaceous Gland Neoplasms	2.5%
523	Tachycardia	2.5%
524	Tachyarrhythmia	2.5%
525	Porokeratosis	2.5%
526	Gianotti-Crosti Syndrome	2.5%
527	Keratoderma, Palmoplantar	2.5%
528	Aortic coarctation	2.5%
529	Cor Triatriatum	2.5%
530	Coronary Vessel Anomalies	2.5%
531	Patent ductus arteriosus	2.5%
532	Ebstein Anomaly	2.5%
533	Heart Septal Defects	2.5%
534	Tetralogy of Fallot	2.5%
535	Transposition of Great Vessels	2.5%
536	Hypoplastic Left Heart Syndrome	2.5%
537	Dermatitis, Phototoxic	2.4%
538	Pityriasis Lichenoides et Varioliformis Acuta	2.4%
539	Pityriasis Lichenoides	2.4%
540	Phototoxicity	2.4%
541	Hypertension, Renovascular	2.4%
542	Subarachnoid Hemorrhage	2.4%
543	Hypoxia-Ischemia, Brain	2.4%
544	Cerebral Hemorrhage	2.4%
545	Dementia, Vascular	2.4%
546	Angina Pectoris, Variant	2.4%
547	Putaminal Hemorrhage	2.4%
548	Skin Abnormalities	2.4%
549	Skin Diseases, Infectious	2.4%
550	Skin Neoplasms	2.4%
551	Cardiac Output, High	2.4%
552	Myocardial Stunning	2.4%
553	Pigmentation Disorders	2.4%
554	Low Cardiac Output Syndrome	2.4%
555	Cardiomegaly	2.4%
556	Lipomatosis	2.4%
557	Postpericardiotomy Syndrome	2.4%
558	Pruritus	2.4%
559	Erythema	2.4%
560	Necrolytic Migratory Erythema	2.4%
561	Cutaneous Fistula	2.4%
562	Cardiac Hypertrophy	2.4%
563	Nephrogenic Fibrosing Dermopathy	2.4%
564	Nephrogenic Systemic Fibrosis	2.4%
565	Rheumatic Heart Disease	2.4%
566	Foot Ulcer	2.3%
567	Osteoporosis, Postmenopausal	2.3%
568	Pseudohypoparathyroidism	2.3%
569	Mitochondrial Encephalomyopathies	2.3%
570	Myelitis, Transverse	2.3%
571	Xeroderma	2.2%
572	Dextrocardia	2.2%
573	Long QT Syndrome	2.2%
574	anaphylaxis	2.2%
575	Food Allergy	2.2%
576	Anaphylactic shock	2.2%
577	Pituitary Apoplexy	2.2%
578	Melorheostosis	2.2%
579	Osteopetrosis	2.2%
580	Spondylolisthesis	2.2%
581	Hepatic Vein Thrombosis	2.1%
582	Budd-Chiari Syndrome	2.1%
583	Hypertrophic Cardiomyopathy	2.1%
584	Pulmonary Infarction	2.1%
585	Hypertrophic obstructive cardiomyopathy	2.1%
586	Subclavian Steal Syndrome	2.1%
587	Welander Distal Myopathy	2%
588	Urticaria Pigmentosa	2%
589	Mastoiditis	2%
590	Petrositis	2%
591	Acute Generalized Exanthematous Pustulosis	2%
592	Sezary Syndrome	2%
593	Ectodermal Dysplasia	2%
594	Aplasia Cutis Congenita	2%
595	Rheumatoid Vasculitis	2%
596	Sick Sinus Syndrome	1.9%
597	Mucopolysaccharidosis III	1.9%
598	Respiratory Hypersensitivity	1.9%
599	Holoprosencephaly	1.9%
600	Sick Building Syndrome	1.9%
601	Multiple Chemical Sensitivity	1.9%
602	Miller Fisher Syndrome	1.9%
603	Plasmacytoma	1.9%
604	Tumor Lysis Syndrome	1.9%
605	HTLV-I Infections	1.9%
606	Job Syndrome	1.9%
607	Supravalvular aortic stenosis	1.9%
608	Lown-Ganong-Levine Syndrome	1.9%
609	Dermatitis, Irritant	1.9%
610	Acne Conglobata	1.9%
611	Erythema Infectiosum	1.8%
612	Exanthema Subitum	1.8%
613	Cerebral Amyloid Angiopathy	1.8%
614	Muscular Dystrophy, Duchenne	1.8%
615	Carcinoid Heart Disease	1.8%
616	Kernicterus	1.8%
617	Osteomalacia	1.8%
618	Porencephaly	1.8%
619	HIV-Associated Lipodystrophy Syndrome	1.8%
620	Kearns-Sayre syndrome	1.7%
621	Dermatitis, Occupational	1.7%
622	Lymphoma	1.7%
623	Hydrops Fetalis	1.6%
624	Anhidrosis	1.6%
625	Aortic Valve Insufficiency	1.6%
626	Restrictive cardiomyopathy	1.6%
627	Cholesteatoma	1.6%
628	Pressure Ulcer	1.6%
629	Endocardial Fibroelastosis	1.6%
630	Folliculitis	1.6%
631	Foot Dermatoses	1.6%
632	Chronic granulomatous disease	1.6%
633	Gynecomastia	1.6%
634	Heart Rupture, Post-Infarction	1.6%
635	Heavy Chain Disease	1.6%
636	Hypertrichosis	1.6%
637	Hypohidrosis	1.6%
638	Hypotrichosis	1.6%
639	Leg Ulcer	1.6%
640	Miliaria	1.6%
641	Mitral Valve Insufficiency	1.6%
642	Mitral Valve Stenosis	1.6%
643	Myocarditis	1.6%
644	Parakeratosis	1.6%
645	Parapsoriasis	1.6%
646	Pericarditis, Constrictive	1.6%
647	Pityriasis	1.6%
648	Psoriasis	1.6%
649	Pulmonary Valve Insufficiency	1.6%
650	Tricuspid Valve Insufficiency	1.6%
651	Tricuspid Valve Stenosis	1.6%
652	Sweet Syndrome	1.6%
653	Hidradenitis	1.6%
654	Onycholysis	1.6%
655	Miliaria Rubra	1.6%
656	Hyperpigmentation	1.6%
657	Lichenoid Eruptions	1.6%
658	Ventricular Dysfunction, Left	1.6%
659	Right Ventricular Dysfunction	1.6%
660	Chloracne	1.6%
661	Endomyocardial Fibrosis	1.6%
662	Carditis	1.6%
663	Heart Failure, Systolic	1.6%
664	Heart Failure, Diastolic	1.6%
665	Ichthyosis, X-Linked	1.6%
666	Ecthyma	1.6%
667	Subacute Bacterial Endocarditis	1.6%
668	Milk Allergy	1.6%
669	Schnitzler Syndrome	1.6%
670	Wheat Hypersensitivity	1.6%
671	HIV Seropositivity	1.6%
672	Sjogren-Larsson Syndrome	1.6%
673	Adams-Stokes Syndrome	1.6%
674	Atrioventricular Block	1.6%
675	Bundle-Branch Block	1.6%
676	Papillon-Lefevre Disease	1.6%
677	Atrial Premature Complexes	1.6%
678	Sinoatrial Block	1.6%
679	Tachycardia, Paroxysmal	1.6%
680	Supraventricular tachycardia	1.6%
681	Tachycardia, Ventricular	1.6%
682	Wolff-Parkinson-White Syndrome	1.6%
683	Tachycardia, Reciprocating	1.6%
684	Tinea Capitis	1.6%
685	Onychomycosis	1.6%
686	Aortopulmonary Septal Defect	1.6%
687	Double Outlet Right Ventricle	1.6%
688	Endocardial Cushion Defects	1.6%
689	Myocardial bridging	1.6%
690	Aorticopulmonary Septal Defect	1.6%
691	Cockayne Syndrome	1.5%
692	Mucopolysaccharidosis II	1.5%
693	Hyperkeratosis, Epidermolytic	1.5%
694	Acquired Immunodeficiency Syndrome	1.5%
695	AIDS related complex	1.5%
696	Infectious Mononucleosis	1.5%
697	POEMS Syndrome	1.5%
698	Romano-Ward Syndrome	1.4%
699	Acantholysis	1.4%
700	Breast Cyst	1.4%
701	Actinic keratosis	1.4%
702	Pemphigoid, Benign Mucous Membrane	1.4%
703	Piedra	1.4%
704	Sunburn	1.4%
705	Argyria	1.4%
706	Sinus Arrhythmia	1.4%
707	Atrial Fibrillation	1.4%
708	Atrial Flutter	1.4%
709	Edema, Cardiac	1.4%
710	Hirsutism	1.4%
711	Lactation Disorder	1.4%
712	Mastitis	1.4%
713	Ventricular Fibrillation	1.4%
714	Ventricular Flutter	1.4%
715	Parasystole	1.4%
716	Paroxysmal atrial fibrillation	1.4%
717	Bradycardia	1.4%
718	Diabetic Cardiomyopathies	1.4%
719	Adiposis Dolorosa	1.4%
720	Cardiomyopathy, Alcoholic	1.4%
721	Ectopia Cordis	1.4%
722	Pruritus Vulvae	1.4%
723	Sudden Cardiac Death	1.4%
724	Left Ventricular Hypertrophy	1.4%
725	Right Ventricular Hypertrophy	1.4%
726	Single umbilical artery	1.4%
727	Chagas Cardiomyopathy	1.4%
728	Mastocytoma	1.4%
729	Pruritus Ani	1.4%
730	Nose Neoplasms	1.4%
731	Mastocytosis, Systemic	1.4%
732	Diaper Rash	1.4%
733	Albinism	1.4%
734	Erythema Chronicum Migrans	1.4%
735	Renal Osteodystrophy	1.4%
736	Renal rickets	1.4%
737	AIDS-Related Opportunistic Infections	1.3%
738	Hematoma, Subdural	1.3%
739	Hematoma, Epidural, Cranial	1.3%
740	HIV Wasting Syndrome	1.3%
741	Hidradenitis Suppurativa	1.3%
742	AIDS Dementia Complex	1.3%
743	AIDS-Associated Nephropathy	1.3%
744	Radicular Cyst	1.3%
745	Dermatomycoses	1.2%
746	Skin Diseases, Bacterial	1.2%
747	Lipodystrophy	1.2%
748	Dyspnea, Paroxysmal	1.2%
749	Hodgkin Disease	1.2%
750	Leukemia, Plasma Cell	1.2%
751	Lymphoma, Non-Hodgkin	1.2%
752	Leukemia, T-Cell	1.2%
753	Leukemia, B-Cell	1.2%
754	Tachycardia, Atrioventricular Nodal Reentry	1.2%
755	Tachycardia, Ectopic Atrial	1.2%
756	Tachycardia, Ectopic Junctional	1.2%
757	Sinus Tachycardia	1.2%
758	Torsades de Pointes	1.2%
759	Accelerated Idioventricular Rhythm	1.2%
760	Brain Hemorrhage, Traumatic	1.2%
761	Truncus Arteriosus, Persistent	1.2%
762	Wiskott-Aldrich Syndrome	1.2%
763	Tinea Pedis	1.1%
764	Fabry Disease	1.1%
765	Asthma	1.1%
766	Porphyrias, Hepatic	1.1%
767	Dural Arteriovenous Fistula	1.1%
768	Hematoma, Subdural, Intracranial	1.1%
769	Hematoma, Subdural, Chronic	1.1%
770	Hematoma, Subdural, Acute	1.1%
771	Composite Lymphoma	1.1%
772	Aortic Valve Prolapse	1.1%
773	Lichen Planus	1.1%
774	Melanosis	1.1%
775	Chloasma	1.1%
776	Pityriasis Rosea	1.1%
777	Pityriasis Rubra Pilaris	1.1%
778	Tricuspid Valve Prolapse	1.1%
779	Vitiligo	1.1%
780	Lichen Nitidus	1.1%
781	Takotsubo Cardiomyopathy	1.1%
782	Mycetoma	1.1%
783	Lymphangioleiomyomatosis	1.1%
784	Turner Syndrome	1.1%
785	Asthma, Exercise-Induced	1%
786	Status Asthmaticus	1%
787	Lymphoma, Follicular	1%
788	T-Cell Lymphoma	1%
789	Mantle cell lymphoma	1%
790	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1%
791	Leukemia, Large Granular Lymphocytic	1%
792	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1%
793	Aspergillosis, Allergic Bronchopulmonary	1%
794	Alopecia	0.9%
795	Sweating, Gustatory	0.9%
796	Androgenetic Alopecia	0.9%
797	Auriculotemporal Syndrome	0.9%
798	Lice Infestations	0.9%
799	Breast Neoplasms, Male	0.9%
800	Triple Negative Breast Neoplasms	0.9%
801	Asthma, Occupational	0.9%
802	Sinus Arrest, Cardiac	0.9%
803	Galactorrhea	0.9%
804	Farmer's Lung	0.9%
805	Lymphoma, T-Cell, Cutaneous	0.9%
806	Lymphoma, AIDS-Related	0.9%
807	Enteropathy-Associated T-Cell Lymphoma	0.9%
808	Primary Effusion Lymphoma	0.9%
809	Hay fever	0.9%
810	Rhinitis, Allergic, Perennial	0.9%
811	Mycosis Fungoides	0.9%
812	Lymphomatoid Papulosis	0.9%
813	Plasmablastic lymphoma	0.9%
814	Larva Migrans	0.8%
815	Leishmaniasis	0.8%
816	Molluscum Contagiosum	0.8%
817	Onchocerciasis	0.8%
818	Chromoblastomycosis	0.8%
819	Dermatophytosis	0.8%
820	Sporotrichosis	0.8%
821	Tinea	0.8%
822	Tinea Versicolor	0.8%
823	Trichophytosis	0.8%
824	Hyalohyphomycosis	0.8%
825	Lymphomatoid Granulomatosis	0.8%
826	Acanthosis Nigricans	0.8%
827	Alopecia Areata	0.8%
828	Lentigo	0.8%
829	Kartagener Syndrome	0.8%
830	Familial Hypophosphatemic Rickets	0.8%
831	Warts	0.7%
832	Burkitt Lymphoma	0.7%
833	Candidiasis, Chronic Mucocutaneous	0.7%
834	Cutaneous Candidiasis	0.7%
835	Erysipelas	0.7%
836	Staphylococcal Skin Infections	0.7%
837	Variegate Porphyria	0.7%
838	Acute intermittent porphyria	0.7%
839	Porphyria Cutanea Tarda	0.7%
840	Erythrasma	0.7%
841	Carcinoma, Lobular	0.7%
842	Lichen Planus, Oral	0.7%
843	Menkes Kinky Hair Syndrome	0.6%
844	Leishmaniasis, Cutaneous	0.6%
845	Eczema Herpeticum	0.6%
846	Fusariosis	0.6%
847	Blastomycosis	0.6%
848	Rhinoscleroma	0.6%
849	Epidermodysplasia Verruciformis	0.5%
850	Herpes Labialis	0.5%
851	Williams Syndrome	0.5%
852	Staphylococcal Scalded Skin Syndrome	0.5%
853	Condylomata Acuminata	0.5%
854	Furunculosis	0.5%
855	furuncle	0.5%
856	Impetigo	0.5%
857	Peutz-Jeghers Syndrome	0.5%
858	carbuncle	0.4%

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