MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Vasoplegia

(UMLS:C2717957)

Definition:: Condition of low SYSTEMIC VASCULAR RESISTANCE that develops secondary to other conditions such as ANAPHYLAXIS; SEPSIS; SURGICAL SHOCK; and SEPTIC SHOCK. Vasoplegia that develops during or post surgery (e.g., CARDIOPULMONARY BYPASS) is called postoperative vasoplegic syndrome or vasoplegic syndrome.
UMLS ID:: C2717957
MeSH ID:: D056987

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.946

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.767.962

Synonym(s)

Vasoplegia

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Amiodarone	10670119	CTD
2	Methylene Blue	12830064	CTD
3	Norepinephrine	12830064	CTD
4	Vasopressins	15745296	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Reperfusion Injury	44.8%
2	Postoperative Hemorrhage	33.9%
3	Myocardial Reperfusion Injury	33%
4	Primary Graft Dysfunction	32.8%
5	Graft Occlusion, Vascular	31.8%
6	Surgical Wound Dehiscence	31.8%
7	Delayed Emergence from Anesthesia	31.8%
8	Anastomotic Leak	31.8%
9	Postpericardiotomy Syndrome	31%
10	Aortic Aneurysm	30.5%
11	Aortitis	30.5%
12	Leriche Syndrome	30.5%
13	Periphlebitis	30.5%
14	Phlebitis	30.5%
15	Thromboangiitis Obliterans	30.5%
16	Thrombophlebitis	28.7%
17	Myocardial Ischemia	28.1%
18	Aneurysm	27.9%
19	Angiomatosis	27.9%
20	Aortic Diseases	27.9%
21	Arterial Occlusive Diseases	27.9%
22	Hyperemia	27.9%
23	Hypotension	27.9%
24	Superior Vena Cava Syndrome	27.9%
25	Telangiectasis	27.9%
26	Vasculitis	27.9%
27	Venous Insufficiency	27.9%
28	Peripheral Vascular Diseases	27.9%
29	Embolism and Thrombosis	27.9%
30	Angiodysplasia	27.9%
31	Capillary Leak Syndrome	27.9%
32	Prehypertension	27.9%
33	Postphlebitic Syndrome	27.7%
34	Incisional hernia	27.1%
35	Pain, Postoperative	26.1%
36	Retinal Vein Occlusion	25.8%
37	Blue Toe Syndrome	25.7%
38	Failed Back Surgery Syndrome	25.5%
39	Coronary Aneurysm	25.3%
40	Aortic Rupture	25.1%
41	Aortic Aneurysm, Abdominal	25%
42	Aortic Aneurysm, Thoracic	25%
43	Malignant Atrophic Papulosis	24.3%
44	Shwartzman Phenomenon	24.2%
45	Prosthesis Failure	24.1%
46	Corneal Endothelial Cell Loss	24.1%
47	Carotid Artery Thrombosis	23.8%
48	Surgical Wound Infection	23.7%
49	Afferent Loop Syndrome	23.5%
50	Short Bowel Syndrome	23.5%
51	Coronary Thrombosis	23.2%
52	Coronary Artery Disease	23.2%
53	No-Reflow Phenomenon	22.7%
54	Postoperative Nausea and Vomiting	22.7%
55	Intracranial Embolism and Thrombosis	22%
56	Carotid Stenosis	21.9%
57	Intracranial Aneurysm	21.9%
58	Vascular System Injuries	21.8%
59	Moyamoya Disease	21.8%
60	Shock, Cardiogenic	21.3%
61	Compartment syndromes	21.1%
62	Hepatic Veno-Occlusive Disease	21.1%
63	Peliosis Hepatis	21.1%
64	Varicocele	21.1%
65	Polydipsia	21.1%
66	Ascites	20.9%
67	Fibrosis	20.9%
68	Gliosis	20.9%
69	Growth Disorders	20.9%
70	Hemorrhage	20.9%
71	Hyperbilirubinemia	20.9%
72	Hyperplasia	20.9%
73	Hypomenorrhea	20.9%
74	Inflammation	20.9%
75	Intraoperative Complications	20.9%
76	Ischemia	20.9%
77	Lithiasis	20.9%
78	Malacoplakia	20.9%
79	Menstruation Disturbances	20.9%
80	Metaplasia	20.9%
81	Nerve Degeneration	20.9%
82	Ochronosis	20.9%
83	Polymenorrhea	20.9%
84	Sclerosis	20.9%
85	Shock	20.9%
86	Ulcer	20.9%
87	Hyperammonemia	20.9%
88	Hyperamylasemia	20.9%
89	Teratogenesis	20.9%
90	Cardiac Death	20.9%
91	Hypovolemia	20.9%
92	Hyperuricemia	20.9%
93	Leukoaraiosis	20.9%
94	Dysbacteriosis	20.9%
95	Delayed Graft Function	20.9%
96	Cirrhosis	20.9%
97	Neointima	20.9%
98	Dysbiosis	20.9%
99	Cerebrovascular Disorders	20.7%
100	Diabetic Angiopathies	20.7%
101	Splenic Infarction	20.7%
102	Cerebrovascular Insufficiency	20.7%
103	Vascular Neoplasms	20.7%
104	Spinal Cord Vascular Diseases	20.7%
105	Hemorrhoids	20.5%
106	Thoracic Outlet Syndrome	20.5%
107	Aneurysm, Dissecting	20.5%
108	Arteriosclerosis	20.5%
109	Arteritis	20.5%
110	Embolism	20.5%
111	Erythromelalgia	20.5%
112	Fibromuscular Dysplasia	20.5%
113	Malignant Hypertension	20.5%
114	Raynaud Disease	20.5%
115	Thromboembolism	20.5%
116	Thrombosis	20.5%
117	Essential Hypertension	20.5%
118	Aneurysm, Ruptured	20.5%
119	Iliac Aneurysm	20.5%
120	Pulmonary artery stenosis	20.5%
121	White Coat Hypertension	20.5%
122	Systemic Vasculitis	20.5%
123	Embolus	20.5%
124	Coronary heart disease	20.3%
125	Infarction	20.3%
126	Myocardial Infarction	20.3%
127	Shock, Hemorrhagic	20.3%
128	Systemic Inflammatory Response Syndrome	20.3%
129	Acute Coronary Syndrome	20.3%
130	Arteriovenous fistula	20.2%
131	Polyarteritis Nodosa	20%
132	Takayasu Arteritis	20%
133	Intracranial Arteriosclerosis	19.8%
134	Cerebral Atherosclerosis	19.8%
135	Cerebral Arteriosclerosis	19.8%
136	Cerebral Thrombosis	18.8%
137	Intracranial Embolism	18.8%
138	Intracranial Thrombosis	18.8%
139	Intermittent Claudication	17.9%
140	Angina Pectoris	17.7%
141	Dumping Syndrome	17.5%
142	Vasculitis, Central Nervous System	17.4%
143	Sinus Thrombosis, Intracranial	17.2%
144	Hand-Arm Vibration Syndrome	17.1%
145	Vascular Remodeling	16.9%
146	Arteriosclerosis Obliterans	16.9%
147	Atherosclerosis	16.9%
148	Air Embolism	16.9%
149	Endarteritis	16.9%
150	Venous Thrombosis	16.9%
151	Deep Vein Thrombosis	16.9%
152	Venous Thromboembolism	16.9%
153	Coronary Occlusion	16.7%
154	Optic Neuropathy, Ischemic	16.7%
155	Microvascular Angina	16.7%
156	Coronary Stenosis	16.7%
157	Anterior Ischemic Optic Neuropathy	16.7%
158	Mesenteric vascular insufficiency	16.7%
159	ST segment elevation myocardial infarction	16.7%
160	Lemierre Syndrome	16.5%
161	Giant Cell Arteritis	16.5%
162	Temporal Arteritis	16.5%
163	Kounis Syndrome	16.4%
164	Brain Infarction	16.4%
165	Cavernous Sinus Thrombosis	16.4%
166	Sagittal Sinus Thrombosis	16.4%
167	Extravasation of Diagnostic and Therapeutic Materials	16.4%
168	Neoplastic Processes	16.4%
169	Angioedema	16.2%
170	Heart Block	16.2%
171	Tachycardia	16.2%
172	Tachyarrhythmia	16.2%
173	Colitis, Ischemic	16.2%
174	May-Thurner Syndrome	16.1%
175	Subarachnoid Hemorrhage	15.8%
176	Cerebral Hemorrhage	15.8%
177	Necrosis	15.8%
178	Granulomatosis, Orofacial	15.8%
179	Pigmentation Disorders	15.8%
180	Respiratory Aspiration	15.8%
181	Infarction, Middle Cerebral Artery	15.7%
182	Infarction, Anterior Cerebral Artery	15.7%
183	Infarction, Posterior Cerebral Artery	15.7%
184	Embolism, Amniotic Fluid	15.6%
185	Acantholysis	15.5%
186	Chromosome Aberrations	15.5%
187	Dehydration	15.5%
188	Granuloma	15.5%
189	Leukocytosis	15.5%
190	Retinal Artery Occlusion	15.5%
191	Pleocytosis	15.5%
192	Retinal Vasculitis	15.5%
193	Hypertensive Retinopathy	15.5%
194	Sick Sinus Syndrome	15.5%
195	Anterior Compartment Syndrome	15.3%
196	Sinus Arrhythmia	15.3%
197	Atrial Fibrillation	15.3%
198	Atrial Flutter	15.3%
199	Ventricular Fibrillation	15.3%
200	Vasculitis, Leukocytoclastic, Cutaneous	15.3%
201	Ventricular Flutter	15.3%
202	Parasystole	15.3%
203	Paroxysmal atrial fibrillation	15.3%
204	Gastric Antral Vascular Ectasia	15.3%
205	Bradycardia	15.3%
206	Abdominal Compartment Syndrome	15.3%
207	Subarachnoid Hemorrhage, Traumatic	15.1%
208	Carotid Artery, Internal, Dissection	15.1%
209	Carotid Artery Diseases	15.1%
210	Brain Ischemia	15.1%
211	Hypotension, Orthostatic	15.1%
212	Cerebrovascular accident	15.1%
213	Varicose Ulcer	15.1%
214	Vasospasm, Intracranial	15.1%
215	Spinal Cord Ischemia	15.1%
216	Intracranial Arterial Diseases	15.1%
217	Post-Exercise Hypotension	15.1%
218	Sudden infant death syndrome	15%
219	Coronary Restenosis	14.9%
220	Livedo Reticularis	14.9%
221	Angina, Unstable	14.7%
222	Cerebral Infarction	14.6%
223	Heart Diseases	14.6%
224	Brain Stem Infarctions	14.6%
225	Basal Ganglia Hemorrhage	14.6%
226	Vertebral Artery Dissection	14.2%
227	Purpura, Hyperglobulinemic	14.2%
228	Menorrhagia	14%
229	Lateral Medullary Syndrome	13.8%
230	Acute Disease	13.6%
231	Acute-Phase Reaction	13.6%
232	Amenorrhea	13.6%
233	Chronic disease	13.6%
234	Critical Illness	13.6%
235	Sudden death	13.6%
236	Fat necrosis	13.6%
237	Gangrene	13.6%
238	Granuloma, Plasma Cell	13.6%
239	Hematoma	13.6%
240	Iatrogenic Disease	13.6%
241	Multiple Organ Failure	13.6%
242	Oligomenorrhea	13.6%
243	Premenstrual syndrome	13.6%
244	Recurrence	13.6%
245	Retrograde Degeneration	13.6%
246	Retroperitoneal fibrosis	13.6%
247	Serositis	13.6%
248	Subcutaneous Emphysema	13.6%
249	Syndrome	13.6%
250	Wallerian Degeneration	13.6%
251	Pyogenic granuloma	13.6%
252	Exsanguination	13.6%
253	Disease Progression	13.6%
254	Seroma	13.6%
255	Premenstrual Tension	13.6%
256	Infant Death	13.6%
257	Intraoperative Awareness	13.6%
258	Chromosomal Instability	13.6%
259	jaundice	13.6%
260	CREST Syndrome	13.6%
261	Long QT Syndrome	13.4%
262	Putaminal Hemorrhage	13.3%
263	Angina Pectoris, Variant	13.2%
264	Scimitar Syndrome	12.9%
265	Genomic Instability	12.9%
266	Hematoma, Subdural	12.8%
267	Hematoma, Epidural, Cranial	12.8%
268	Pulmonary Embolism	12.8%
269	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	12.8%
270	Sudden Cardiac Death	12.6%
271	Adams-Stokes Syndrome	12.6%
272	Atrioventricular Block	12.6%
273	Bundle-Branch Block	12.6%
274	Atrial Premature Complexes	12.6%
275	Sinoatrial Block	12.6%
276	Tachycardia, Paroxysmal	12.6%
277	Supraventricular tachycardia	12.6%
278	Tachycardia, Ventricular	12.6%
279	Tachycardia, Reciprocating	12.6%
280	Cerebral Arterial Diseases	12.4%
281	Vertebrobasilar Insufficiency	12.4%
282	Anterior Spinal Artery Syndrome	12.4%
283	Basilar Artery Stenosis	12.4%
284	Vertebral Artery Stenosis	12.4%
285	Intracranial Hemorrhage, Hypertensive	12.4%
286	Transient Cerebral Ischemia	12.4%
287	Carotid Artery Injuries	12.3%
288	Mesenteric Vascular Occlusion	12.3%
289	Mucocutaneous Lymph Node Syndrome	12.3%
290	Cardiac Output, High	12.3%
291	Myocardial Stunning	12.3%
292	Low Cardiac Output Syndrome	12.3%
293	Diabetic Retinopathy	12.2%
294	Sturge-Weber Syndrome	12.2%
295	Phantom pain	12.2%
296	Phantom Limb Pain	12.2%
297	Signs and Symptoms	12.2%
298	Pathological Conditions, Anatomical	12.2%
299	Dysmenorrhea	12.1%
300	Azotemia	12.1%
301	Renal hypertension	12.1%
302	Renal Artery Obstruction	12.1%
303	Renal Artery Stenosis	12.1%
304	Hemangioma, Cavernous	12%
305	Muscle Weakness	12%
306	Basal Ganglia Cerebrovascular Disease	12%
307	Vascular Headaches	12%
308	Scurvy	11.9%
309	Sinus Arrest, Cardiac	11.7%
310	Hepatic Vein Thrombosis	11.5%
311	Budd-Chiari Syndrome	11.5%
312	Pulmonary Infarction	11.3%
313	Eye Hemorrhage	11.3%
314	Hematoma, Subdural, Intracranial	11.2%
315	Hematoma, Subdural, Chronic	11.2%
316	Hematoma, Subdural, Acute	11.2%
317	Subclavian Steal Syndrome	11.1%
318	Endotoxic shock	11%
319	Septic Shock	11%
320	Toxic Shock Syndrome	11%
321	Hemoptysis	11%
322	Pregnancy Complications, Cardiovascular	10.9%
323	Cardiovascular Abnormalities	10.9%
324	Tachycardia, Atrioventricular Nodal Reentry	10.8%
325	Tachycardia, Ectopic Atrial	10.8%
326	Tachycardia, Ectopic Junctional	10.8%
327	Sinus Tachycardia	10.8%
328	Torsades de Pointes	10.8%
329	Accelerated Idioventricular Rhythm	10.8%
330	Ecchymosis	10.8%
331	Petechiae	10.8%
332	Purpura	10.8%
333	Asphyxia	10.7%
334	Granuloma, Respiratory Tract	10.7%
335	Shock, Traumatic	10.7%
336	Romano-Ward Syndrome	10.4%
337	Cardiotoxicity	10.4%
338	Disease susceptibility	10.3%
339	Fetal Death	10.3%
340	Foreign-Body Reaction	10.3%
341	Gastrointestinal Hemorrhage	10.3%
342	Cardiomegaly	10.3%
343	Hemarthrosis	10.3%
344	Hemoperitoneum	10.3%
345	Hemothorax	10.3%
346	Neoplasm Invasiveness	10.3%
347	Neoplasm Metastasis	10.3%
348	Neoplasm Recurrence, Local	10.3%
349	Injection Site Reaction	10.3%
350	Retrobulbar Hemorrhage	10.3%
351	Aseptic Necrosis of Bone	10.3%
352	Peritoneal Fibrosis	10.3%
353	Carcinogenesis	10.3%
354	Neurogenic Inflammation	10.3%
355	Perinatal death	10.3%
356	Infusion site reaction	10.3%
357	Cardiac Hypertrophy	10.3%
358	Nephrogenic Fibrosing Dermopathy	10.3%
359	Encapsulating Peritoneal Sclerosis	10.3%
360	Suppuration	10.3%
361	Nephrogenic Systemic Fibrosis	10.3%
362	Metastasis	10.3%
363	Aortic Valve Stenosis	10.2%
364	Cardiomyopathy, Dilated	10.2%
365	Dental Pulp Necrosis	10.2%
366	Granuloma, Foreign-Body	10.2%
367	Mediastinal Emphysema	10.2%
368	Pulmonary Valve Stenosis	10.2%
369	Facies	10.2%
370	Embryo Loss	10.2%
371	Tissue Adhesions	10.1%
372	Ischemic contracture	10.1%
373	Hematoma, Epidural, Spinal	10.1%
374	Sex Chromosome Aberrations	10.1%
375	Uterine hemorrhage	10.1%
376	Angioedemas, Hereditary	10.1%
377	Tricuspid Atresia	10.1%
378	Arrhythmogenic Right Ventricular Dysplasia	10.1%
379	Cryoglobulinemia	10%
380	Jaundice, Obstructive	10%
381	Leukomalacia, Periventricular	10%
382	Chromosome Fragility	9.9%
383	Diabetic Foot	9.9%
384	Hypertension, Renovascular	9.9%
385	Hypoxia-Ischemia, Brain	9.9%
386	Hereditary Angioedema Type III	9.8%
387	Hereditary Angioedema Types I and II	9.8%
388	Dementia, Vascular	9.8%
389	Cardiac Tamponade	9.3%
390	Endocarditis	9.3%
391	Cardiac Arrest	9.3%
392	Heart failure	9.3%
393	Pericardial effusion	9.3%
394	Pericarditis	9.3%
395	Pneumopericardium	9.3%
396	Cor pulmonale	9.3%
397	Ventricular Outflow Obstruction	9.3%
398	Ventricular Dysfunction	9.3%
399	Cardiomyopathies	9.3%
400	Pleuropericarditis	9.3%
401	Epistaxis	9.2%
402	Granulomatosis with polyangiitis	9%
403	Cerebral Amyloid Angiopathy	8.9%
404	Hypertrophic Cardiomyopathy	8.8%
405	Hypertrophic obstructive cardiomyopathy	8.8%
406	Shy-Drager Syndrome	8.5%
407	Edema, Cardiac	8.5%
408	Drowning	8.5%
409	Trisomy	8.5%
410	Hematoma, Subdural, Spinal	8.4%
411	Supravalvular aortic stenosis	8.3%
412	Lown-Ganong-Levine Syndrome	8.3%
413	Pituitary Apoplexy	8.3%
414	Fetal Growth Retardation	8.2%
415	DNA Degradation, Necrotic	8.2%
416	Aneuploidy	8.2%
417	Polyploidy	8.2%
418	Microsatellite Instability	8.2%
419	Cicatrix	8.1%
420	Aortic coarctation	8.1%
421	Cor Triatriatum	8.1%
422	Coronary Vessel Anomalies	8.1%
423	Patent ductus arteriosus	8.1%
424	Ebstein Anomaly	8.1%
425	Heart Septal Defects	8.1%
426	Hematuria	8.1%
427	Tetralogy of Fallot	8.1%
428	Transposition of Great Vessels	8.1%
429	Granuloma Annulare	8.1%
430	Hypoplastic Left Heart Syndrome	8.1%
431	Chromosome Breakage	8.1%
432	Bacterial Endocarditis	8%
433	Brain Death	8%
434	Hematemesis	8%
435	Purpura Fulminans	7.9%
436	Cross Infection	7.7%
437	Hyphema	7.7%
438	Retinal Neovascularization	7.7%
439	Septicemia	7.7%
440	Vitreous Hemorrhage	7.7%
441	Sepsis	7.7%
442	Abscess	7.6%
443	Empyema	7.6%
444	Femur Head Necrosis	7.6%
445	Fetal Resorption	7.6%
446	Lymphatic Metastasis	7.6%
447	Neoplasms, Unknown Primary	7.6%
448	Peptic Ulcer Hemorrhage	7.6%
449	Left Ventricular Hypertrophy	7.6%
450	Leukemic Infiltration	7.6%
451	Right Ventricular Hypertrophy	7.6%
452	Premenstrual Dysphoric Disorder	7.6%
453	Choroidal Neovascularization	7.6%
454	Neoplasm Micrometastasis	7.6%
455	Behcet Syndrome	7.5%
456	Lupus Vasculitis, Central Nervous System	7.5%
457	Waldenstrom Macroglobulinemia	7.5%
458	Multiple Myeloma	7.5%
459	Cicatrix, Hypertrophic	7.5%
460	Metrorrhagia	7.5%
461	Rheumatoid Vasculitis	7.1%
462	Asthenia	7%
463	Body Temperature Changes	7%
464	Calculi	7%
465	Cyanosis	7%
466	Edema	7%
467	Failure to Thrive	7%
468	Fatigue	7%
469	Feminization	7%
470	Fetal Distress	7%
471	Hernia	7%
472	Hypertrophy	7%
473	Motion Sickness	7%
474	Nails, Malformed	7%
475	polyps	7%
476	Rupture, Spontaneous	7%
477	Signs and Symptoms, Digestive	7%
478	Signs and Symptoms, Respiratory	7%
479	Skin Manifestations	7%
480	Chills	7%
481	Lassitude	7%
482	Enterocele	7%
483	Atheroma	7%
484	Pseudophakia	7%
485	Urological Manifestations	7%
486	Stenosis	7%
487	Facial asymmetry	7%
488	Mobility Limitation	7%
489	Somnolence	7%
490	Plaque, Amyloid	7%
491	Plaque, Atherosclerotic	7%
492	Giant Cell Epulis	6.9%
493	Aortic Valve Insufficiency	6.8%
494	Restrictive cardiomyopathy	6.8%
495	Endocardial Fibroelastosis	6.8%
496	Heart Rupture, Post-Infarction	6.8%
497	Mitral Valve Insufficiency	6.8%
498	Mitral Valve Stenosis	6.8%
499	Myocarditis	6.8%
500	Pericarditis, Constrictive	6.8%
501	Pulmonary Valve Insufficiency	6.8%
502	Tricuspid Valve Insufficiency	6.8%
503	Tricuspid Valve Stenosis	6.8%
504	Ventricular Dysfunction, Left	6.8%
505	Right Ventricular Dysfunction	6.8%
506	Endomyocardial Fibrosis	6.8%
507	Carditis	6.8%
508	Heart Failure, Systolic	6.8%
509	Heart Failure, Diastolic	6.8%
510	Rheumatic Heart Disease	6.8%
511	Ataxia Telangiectasia	6.8%
512	Pseudoxanthoma Elasticum	6.7%
513	Dextrocardia	6.7%
514	Wolff-Parkinson-White Syndrome	6.6%
515	Viremia	6.6%
516	Parasitemia	6.6%
517	Aortopulmonary Septal Defect	6.6%
518	Double Outlet Right Ventricle	6.6%
519	Endocardial Cushion Defects	6.6%
520	Myocardial bridging	6.6%
521	Aorticopulmonary Septal Defect	6.6%
522	Micronuclei, Chromosome-Defective	6.6%
523	Retinal Hemorrhage	6.2%
524	Choroid Hemorrhage	6.1%
525	Melena	6.1%
526	Dyspnea, Paroxysmal	6%
527	Postpartum Hemorrhage	6%
528	Gingival Hemorrhage	6%
529	Keloid	6%
530	Monosomy	6%
531	Tetraploidy	6%
532	Stillbirth	6%
533	Truncus Arteriosus, Persistent	5.9%
534	Abdominal Pain	5.9%
535	Subacute Combined Degeneration	5.8%
536	Thrombocytopenic purpura	5.8%
537	Eosinophilic Granuloma	5.7%
538	Aortic Valve Prolapse	5.6%
539	Tricuspid Valve Prolapse	5.6%
540	Takotsubo Cardiomyopathy	5.6%
541	Cyst	5.5%
542	Eye Manifestations	5.5%
543	Neurologic Manifestations	5.5%
544	Leukoplakia	5.3%
545	Reticulocytosis	5.3%
546	Airway Remodeling	5.3%
547	Subacute Bacterial Endocarditis	5.2%
548	Ventricular Remodeling	5.2%
549	Alopecia	5.1%
550	Androgenetic Alopecia	5.1%
551	Bacteremia	5.1%
552	Cellulitis	5.1%
553	Diabetic Cardiomyopathies	5.1%
554	Kernicterus	5.1%
555	Cell Transformation, Viral	5.1%
556	Cardiomyopathy, Alcoholic	5%
557	Ectopia Cordis	5%
558	Noonan Syndrome	5%
559	Single umbilical artery	5%
560	Renal Colic	5%
561	Chagas Cardiomyopathy	5%
562	Fungemia	5%
563	Brain Hemorrhage, Traumatic	4.9%
564	Eye pain	4.8%
565	Muscular Atrophy	4.7%
566	Purpura, Thrombotic Thrombocytopenic	4.7%
567	Abdomen, Acute	4.6%
568	Anorexia	4.5%
569	Anoxia	4.5%
570	Constipation	4.5%
571	Diarrhea	4.5%
572	Dyspepsia	4.5%
573	Eructation	4.5%
574	Fever	4.5%
575	Flatulence	4.5%
576	Flushing	4.5%
577	Halitosis	4.5%
578	Heartburn	4.5%
579	Diaphragmatic Hernia	4.5%
580	Hiccough	4.5%
581	Hypercalciuria	4.5%
582	Hypercapnia	4.5%
583	Hyperphagia	4.5%
584	Intestinal Polyps	4.5%
585	Nausea	4.5%
586	Pallor	4.5%
587	Psychophysiologic Disorders	4.5%
588	Splenomegaly	4.5%
589	Vomiting	4.5%
590	Hypocapnia	4.5%
591	Dyschezia	4.5%
592	Hypoxia	4.5%
593	Hyperoxia	4.5%
594	Lower Urinary Tract Symptoms	4.5%
595	Hypoxemia	4.5%
596	Urinoma	4.5%
597	Marfan Syndrome	4.5%
598	Endotoxemia	4.5%
599	Granuloma, Laryngeal	4.4%
600	MELAS Syndrome	4.4%
601	Carcinoid Heart Disease	4.4%
602	Hypergammaglobulinemia	4.2%
603	Diverticulum	4.1%
604	Diverticulosis	4.1%
605	Autoimmune thrombocytopenia	3.7%
606	Immune thrombocytopenic purpura	3.7%
607	Sarcopenia	3.6%
608	Philadelphia Chromosome	3.6%
609	Respiratory Tract Fistula	3.6%
610	Waterhouse-Friderichsen Syndrome	3.6%
611	Apnea	3.4%
612	Cheyne-Stokes Respiration	3.4%
613	Decerebrate State	3.4%
614	Dyspnea	3.4%
615	Hemiparesis	3.4%
616	Hepatomegaly	3.4%
617	Hyperventilation	3.4%
618	Meningism	3.4%
619	Mouth Breathing	3.4%
620	Paresis	3.4%
621	Parovarian Cyst	3.4%
622	Pruritus	3.4%
623	Seizures	3.4%
624	Sensation Disorders	3.4%
625	Sneezing	3.4%
626	Spermatocele	3.4%
627	Erythema	3.4%
628	Oral Fistula	3.4%
629	Complex partial seizures	3.4%
630	Necrolytic Migratory Erythema	3.4%
631	Tachypnea	3.4%
632	Monoparesis	3.4%
633	Cutaneous Fistula	3.4%
634	Gait Disorders, Neurologic	3.4%
635	Neuromuscular Manifestations	3.4%
636	Fabry Disease	3.4%
637	Mental Fatigue	3.4%
638	Hirsutism	3.4%
639	Dural Arteriovenous Fistula	3.4%
640	Orthostatic intolerance	3.4%
641	Hypoventilation	3.4%
642	Back Pain	3.4%
643	Bulimia	3.4%
644	Neck Pain	3.4%
645	Chest Pain	3.4%
646	Colonic Polyps	3.4%
647	Dizziness	3.4%
648	Dysuria	3.4%
649	Facial Pain	3.4%
650	Fever of Unknown Origin	3.4%
651	Flank Pain	3.4%
652	Headache	3.4%
653	Nocturia	3.4%
654	Pain, Intractable	3.4%
655	Pelvic Pain	3.4%
656	Snoring	3.4%
657	Chronic pain	3.4%
658	Lightheadedness	3.4%
659	Pain, Referred	3.4%
660	Prostatism	3.4%
661	Throbbing Headache	3.4%
662	Labor Pain	3.4%
663	Cancer Pain	3.4%
664	Nociceptive Pain	3.4%
665	Vaginal Fistula	3.4%
666	Rectocele	3.4%
667	Body Weight Changes	3.3%
668	Candidemia	3.2%
669	Gait Ataxia	3%
670	Hoarseness	3%
671	Sleep Wake Disorders	2.9%
672	Pupil Disorders	2.9%
673	Neurobehavioral Manifestations	2.9%
674	Body Weight	2.8%
675	Emaciation	2.8%
676	Low Back Pain	2.8%
677	Visceral Pain	2.8%
678	Nasal Polyps	2.8%
679	Pleural Rub	2.7%
680	Rales	2.7%
681	Respiratory Sounds	2.7%
682	Rhonchi	2.7%
683	Stridor	2.7%
684	Wheezing	2.7%
685	Asterixis	2.7%
686	Ballismus	2.7%
687	Vertigo	2.7%
688	Pain	2.7%
689	Ache	2.7%
690	Meningocele	2.7%
691	Oliguria	2.7%
692	Polyuria	2.7%
693	Proteinuria	2.7%
694	Urinary Calculi	2.7%
695	Encephalocele	2.7%
696	Underweight	2.6%
697	Overweight	2.6%
698	Akathisia	2.6%
699	Restlessness	2.6%
700	Psychomotor Agitation	2.6%
701	Turner Syndrome	2.6%
702	Biliary Fistula	2.6%
703	Gastric Fistula	2.6%
704	Congenital diaphragmatic hernia	2.6%
705	Morning Sickness	2.6%
706	Vesicovaginal Fistula	2.6%
707	Anosmia	2.5%
708	Ataxia	2.5%
709	Athetosis	2.5%
710	Catalepsy	2.5%
711	Dental Fistula	2.5%
712	Dystonia	2.5%
713	Hemiplegia	2.5%
714	Locked-In Syndrome	2.5%
715	Muscle Hypertonia	2.5%
716	Muscle hypotonia	2.5%
717	Myoclonus	2.5%
718	Myotonia	2.5%
719	Neuralgia	2.5%
720	Oroantral Fistula	2.5%
721	Paraplegia	2.5%
722	Pseudobulbar Palsy	2.5%
723	Quadriplegia	2.5%
724	Spasm	2.5%
725	Spastic Paraplegia	2.5%
726	Status Epilepticus	2.5%
727	Taste Disorders	2.5%
728	Tremor	2.5%
729	Monoplegia	2.5%
730	Hypokinesia	2.5%
731	Gastroparesis	2.5%
732	Paraparesis	2.5%
733	Bradykinesia	2.5%
734	Waxy flexibility	2.5%
735	Action Tremor	2.5%
736	Resting Tremor	2.5%
737	Dysosmia	2.5%
738	Quadriparesis	2.5%
739	Olfaction Disorders	2.5%
740	Myokymia	2.5%
741	Somatosensory Disorders	2.5%
742	Neuropathic pain	2.5%
743	Hyperkinesia	2.5%
744	Intention tremor	2.5%
745	Cachexia	2.5%
746	Rectal Prolapse	2.5%
747	Uterine Prolapse	2.5%
748	Vaginal Prolapse	2.5%
749	Williams Syndrome	2.5%
750	Weight Gain	2.5%
751	Gait Apraxia	2.5%
752	Kartagener Syndrome	2.4%
753	Voice Disorders	2.3%
754	Voice Disturbance	2.3%
755	Gagging	2.3%
756	Leukoplakia, Oral	2.2%
757	Kearns-Sayre syndrome	2.2%
758	Umbilical hernia	2.1%
759	Toothache	2.1%
760	Alexia	2.1%
761	Vision Disorders	2.1%
762	Metamorphopsia	2.1%
763	Dyslexia	2.1%
764	Visual Impairment	2.1%
765	Hyperemesis Gravidarum	2.1%
766	Dysgeusia	2.1%
767	Formication	2.1%
768	Hyperalgesia	2.1%
769	Hyperesthesia	2.1%
770	Hypesthesia	2.1%
771	Language Disorders	2.1%
772	Numbness	2.1%
773	Paresthesia	2.1%
774	Paraparesis, Spastic	2.1%
775	Trismus	2.1%
776	Epilepsia Partialis Continua	2.1%
777	Hypogeusia	2.1%
778	Brown-Sequard Syndrome	2.1%
779	Lockjaw	2.1%
780	Allodynia	2.1%
781	Ageusia	2.1%
782	Bronchial Fistula	2.1%
783	Metatarsalgia	2.1%
784	Pancreatic Fistula	2.1%
785	Alice in Wonderland Syndrome	2%
786	Anisocoria	2%
787	Confusion	2%
788	Facial paralysis	2%
789	Intestinal Fistula	2%
790	Lethargy	2%
791	Memory Disorders	2%
792	Muscle Cramp	2%
793	Perceptual Disorders	2%
794	Psychomotor Disorders	2%
795	Tonic Pupil	2%
796	Anhedonia	2%
797	Disorientation	2%
798	Gastroschisis	2%
799	Enterocutaneous Fistula	2%
800	Fetal Hypoxia	2%
801	Facial Paresis	2%
802	Memory Loss	2%
803	Hemisensory Neglect	2%
804	Dysacusis	2%
805	Mastodynia	2%
806	Respiratory Paralysis	2%
807	Salivary Gland Fistula	2%
808	Chorea	2%
809	Cystocele	2%
810	Tetany	2%
811	Urinary Incontinence	2%
812	Breakthrough Pain	2%
813	Albuminuria	2%
814	Hemoglobinuria	2%
815	Jet Lag Syndrome	1.9%
816	Reflex, Abnormal	1.9%
817	Hyporeflexia	1.9%
818	Hyperreflexia	1.9%
819	Birth Weight	1.9%
820	Agraphia	1.9%
821	Anomia	1.9%
822	Cluttering	1.9%
823	Language Development Disorders	1.9%
824	Speech Disorders	1.9%
825	Syncope	1.9%
826	Stupor	1.9%
827	Dysgraphia	1.9%
828	Presyncope	1.9%
829	Dyslalia	1.9%
830	Aphasia	1.7%
831	Articulation Disorders	1.7%
832	Echolalia	1.7%
833	Stuttering	1.7%
834	Dysphasia	1.7%
835	Consciousness Disorders	1.7%
836	Mental Retardation	1.7%
837	Depressed Level of Consciousness	1.7%
838	Mental deficiency	1.7%
839	Intellectual Disability	1.7%
840	Catatonia	1.7%
841	Musculoskeletal Pain	1.7%
842	Ophthalmoplegia	1.7%
843	External Ophthalmoplegia	1.7%
844	Dysarthria	1.7%
845	Diplopia	1.7%
846	Muscle Rigidity	1.7%
847	Muscle Spasticity	1.7%
848	Scotoma	1.7%
849	Photophobia	1.7%
850	Cogwheel Rigidity	1.7%
851	Hemifacial Spasm	1.7%
852	Amaurosis	1.7%
853	Blindness	1.7%
854	Nuchal Rigidity	1.7%
855	Aphonia	1.7%
856	Arthralgia	1.7%
857	Sleep Deprivation	1.7%
858	Polyarthralgia	1.7%
859	Dysphonia	1.7%
860	Agnosia	1.7%
861	Apraxias	1.7%
862	Hallucinations	1.7%
863	Hemianopsia	1.7%
864	Hyperacusis	1.7%
865	Tinnitus	1.7%
866	Visual Agnosia	1.7%
867	Anosognosia	1.7%
868	Wernicke-Korsakoff Syndrome	1.7%
869	Phonophobia	1.7%
870	Hearing Loss	1.7%
871	Cerebrospinal Fluid Otorrhea	1.7%
872	Cerebrospinal Fluid Rhinorrhea	1.7%
873	Cerebellar Ataxia	1.7%
874	Torticollis	1.7%
875	Sciatica	1.6%
876	Urge Incontinence	1.6%
877	Tardive Dyskinesia	1.6%
878	Obesity	1.6%
879	Amaurosis Fugax	1.5%
880	Blindness, Cortical	1.5%
881	Dyscalculia	1.5%
882	Hydrops Fetalis	1.5%
883	Deafness	1.5%
884	Hearing Loss, Sudden	1.5%
885	Gerstmann Syndrome	1.5%
886	Hearing Loss, Bilateral	1.5%
887	Hearing Loss, High-Frequency	1.5%
888	Hearing Loss, Mixed Conductive-Sensorineural	1.5%
889	Prosopagnosia	1.5%
890	Apraxia, Ideomotor	1.5%
891	Persistent Vegetative State	1.5%
892	Charles Bonnet Syndrome	1.5%
893	Hearing Loss, Unilateral	1.5%
894	Complete Hearing Loss	1.5%
895	Alien Hand Syndrome	1.5%
896	Deaf Mutism	1.5%
897	Vocal Cord Paralysis	1.5%
898	Fetal Weight	1.5%
899	Urinary Bladder Fistula	1.4%
900	Mutism	1.4%
901	Selective Mutism	1.4%
902	Tinea Pedis	1.4%
903	Amblyopia	1.4%
904	Amnesia	1.4%
905	Delirium	1.4%
906	Horner Syndrome	1.4%
907	Dissociative Amnesia	1.4%
908	Color blindness	1.4%
909	Global Amnesia	1.4%
910	Rectal Fistula	1.4%
911	Anal Fistula	1.4%
912	Shoulder Pain	1.4%
913	Alexia, Pure	1.4%
914	Pediatric Obesity	1.4%
915	Dyskinesia, Drug-Induced	1.3%
916	Alcohol Withdrawal Seizures	1.2%
917	Retrograde amnesia	1.2%
918	Amnesia, Anterograde	1.2%
919	Akathisia, Drug-Induced	1.2%
920	Myalgia	1.2%
921	Kidney Calculi	1.1%
922	Ureteral Calculi	1.1%
923	Amnesia, Transient Global	1.1%
924	Auditory Perceptual Disorders	1%
925	Ophthalmoplegic Migraine	0.9%
926	Progressive supranuclear palsy	0.9%

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