MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lichen Planus, Oral

(UMLS:C0206139)

Definition:: Oral lesions accompanying cutaneous lichen planus or often occurring alone. The buccal mucosa, lips, gingivae, floor of the mouth, and palate are usually affected (in a descending order of frequency). Typically, oral lesions consist of radiating white or gray, velvety, threadlike lines, arranged in a reticular pattern, at the intersection of which there may be minute, white, elevated dots or streaks (Wickham's striae). (Jablonski, Illustrated Dictionary of Dentistry)
UMLS ID:: C0206139
MeSH ID:: D017676

Classification 1:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.465.397

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.859.475.560.397

Synonym(s)

Lichen Planus, Oral

OLP - Oral lichen planus

Oral Lichen Planus

Oral lichen planus

lichen oral planus

lichen planus oral

oral lichen planus

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Tretinoin		4685585	CTD
2	naphthalan		25580784	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Pityriasis Lichenoides et Varioliformis Acuta	28.5%
2	Pityriasis Lichenoides	28.5%
3	Facial Hemiatrophy	28.5%
4	Melkersson-Rosenthal Syndrome	28.5%
5	Burning Mouth Syndrome	27.4%
6	Lip Diseases	27.4%
7	Microglossia	27.4%
8	Oral Submucous Fibrosis	27.4%
9	Periodontal Diseases	27.4%
10	Salivary Gland Diseases	27.4%
11	Stomatitis	27.4%
12	Tongue Diseases	27.4%
13	Oral Ulcer	27.4%
14	Lichen Nitidus	24.9%
15	Gingival Recession	24.7%
16	Parotitis	24.7%
17	Gingival Atrophy	24.7%
18	Parotid Neoplasms	24.5%
19	Salivary Gland Fistula	23.9%
20	Salivary Gland Neoplasms	23.9%
21	Tongue Neoplasms	23.9%
22	Bell Palsy	23.7%
23	Tooth Loss	22.1%
24	Mouth Abnormalities	22%
25	Gingival Hemorrhage	21.8%
26	Facial Nerve Diseases	20.8%
27	Granulomatosis, Orofacial	20.8%
28	Oral candidiasis	20.4%
29	Mouth Neoplasms	20.4%
30	Oral Fistula	20.4%
31	Cheilitis	20.1%
32	Drooling	20.1%
33	Gingival Diseases	20.1%
34	Glossitis	20.1%
35	Macroglossia	20.1%
36	Periodontitis	20.1%
37	Sialadenitis	20.1%
38	Sialometaplasia, Necrotizing	20.1%
39	Sialorrhea	20.1%
40	Aphthous Stomatitis	20.1%
41	Xerostomia	20.1%
42	Glossoptosis	20.1%
43	Peri-Implantitis	20.1%
44	Parapsoriasis	19.6%
45	Pityriasis	19.6%
46	Psoriasis	19.6%
47	Gingivitis	16.6%
48	Glossitis, Benign Migratory	16.6%
49	Pericoronitis	16.6%
50	Aggressive Periodontitis	16.6%
51	Gingival Overgrowth	16.6%
52	Facial paralysis	16.2%
53	Facial Paresis	16.2%
54	Hemifacial Spasm	16%
55	Macrostomia	15.9%
56	Microstomia	15.9%
57	Lupus Erythematosus, Cutaneous	15.6%
58	Panniculitis	15.6%
59	Systemic Scleroderma	15.6%
60	Morphea	15.6%
61	Breast Diseases	15.4%
62	Dermatitis	15.4%
63	Exanthema	15.4%
64	Facial Dermatoses	15.4%
65	Hair Diseases	15.4%
66	Hand Dermatoses	15.4%
67	keratoacanthoma	15.4%
68	Keratosis	15.4%
69	Nail Diseases	15.4%
70	Photosensitivity Disorders	15.4%
71	Prurigo	15.4%
72	Pyoderma	15.4%
73	Rosacea	15.4%
74	Sebaceous Gland Diseases	15.4%
75	Skin Diseases, Vesiculobullous	15.4%
76	Skin Ulcer	15.4%
77	Sweat Gland Diseases	15.4%
78	Skin Diseases, Vascular	15.4%
79	Acneiform Eruptions	15.4%
80	Ocular Rosacea	15.4%
81	Subcorneal pustular dermatosis	15.4%
82	Erythematotelangiectatic Rosacea	15.4%
83	Papulopustular Rosacea	15.4%
84	Chronic Actinic Dermatitis	15.4%
85	Facial Neuralgia	15.1%
86	Pyoderma Gangrenosum	15.1%
87	Behcet Syndrome	15%
88	Dental Fistula	14.9%
89	Oroantral Fistula	14.9%
90	Gingival Hyperplasia	14.8%
91	Gingival Hypertrophy	14.8%
92	Tooth Diseases	14.4%
93	Giant Cell Epulis	13%
94	Toxic Epidermal Necrolysis	12.9%
95	Stevens-Johnson Syndrome	12.9%
96	Acne Vulgaris	12.6%
97	Contact Dermatitis	12.6%
98	Eczema	12.6%
99	Erythema Multiforme	12.6%
100	Intertrigo	12.6%
101	Neurodermatitis	12.6%
102	Rhinophyma	12.6%
103	Perioral Dermatitis	12.6%
104	Acne	12.6%
105	Vesicular Stomatitis	12.5%
106	Alveolar Bone Loss	12.4%
107	Trigeminal Nerve Disorder	12.3%
108	Foot Diseases	12.1%
109	Radicular Cyst	11.8%
110	Skin Abnormalities	11.7%
111	Skin Diseases, Infectious	11.7%
112	Skin Neoplasms	11.7%
113	Pigmentation Disorders	11.7%
114	Pityriasis Rosea	11.6%
115	Pityriasis Rubra Pilaris	11.6%
116	Herpes Labialis	11.5%
117	Lipomatosis	11.5%
118	Pruritus	11.5%
119	Erythema	11.5%
120	Necrolytic Migratory Erythema	11.5%
121	Cutaneous Fistula	11.5%
122	Nephrogenic Fibrosing Dermopathy	11.5%
123	Nephrogenic Systemic Fibrosis	11.5%
124	Jaw Diseases	11.2%
125	Pharyngeal Diseases	11.2%
126	Mumps	11%
127	Trigeminal Neuralgia	11%
128	Dermatitis, Atopic	10.7%
129	Epidermolysis Bullosa	10.7%
130	Cleft Palate	10.4%
131	Connective Tissue Diseases	10.2%
132	Dermatitis Herpetiformis	10.2%
133	Mobius Syndrome	10.1%
134	Dermatomyositis	10.1%
135	Xeroderma Pigmentosum	10.1%
136	Herpes Zoster Oticus	10.1%
137	Acrodermatitis	10%
138	Sebaceous Gland Neoplasms	10%
139	Porokeratosis	10%
140	Gianotti-Crosti Syndrome	10%
141	Keratoderma, Palmoplantar	10%
142	Leukoplakia, Oral	10%
143	Foot Ulcer	10%
144	Palatal Neoplasms	9.9%
145	Bruxism	9.1%
146	Dental Leakage	9.1%
147	Hypercementosis	9.1%
148	Malocclusion	9.1%
149	Tooth Crowding	9.1%
150	Tooth Discoloration	9.1%
151	Tooth Demineralization	9.1%
152	Tooth Ankylosis	9.1%
153	Necrobiosis Lipoidica Diabeticorum	9.1%
154	Mastocytosis	9.1%
155	Ulcerative stomatitis	9%
156	Dermatitis, Phototoxic	8.9%
157	Phototoxicity	8.9%
158	Panniculitis, Lupus Erythematosus	8.8%
159	Facial Nerve Injuries	8.5%
160	Xeroderma	8.5%
161	Anhidrosis	8.4%
162	Cholesteatoma	8.4%
163	Pressure Ulcer	8.4%
164	Folliculitis	8.4%
165	Foot Dermatoses	8.4%
166	Gynecomastia	8.4%
167	Hypertrichosis	8.4%
168	Hypohidrosis	8.4%
169	Hypotrichosis	8.4%
170	Leg Ulcer	8.4%
171	Miliaria	8.4%
172	Parakeratosis	8.4%
173	Sweet Syndrome	8.4%
174	Hidradenitis	8.4%
175	Onycholysis	8.4%
176	Miliaria Rubra	8.4%
177	Hyperpigmentation	8.4%
178	Chloracne	8.4%
179	Lupus Erythematosus, Discoid	8.4%
180	Scleroderma, Limited	8.4%
181	Temporomandibular Joint Disorders	8.4%
182	Cutis Laxa	8.1%
183	Dental Enamel Hypoplasia	8%
184	Hypodontia	8%
185	Urticaria Pigmentosa	7.9%
186	Erythema Induratum	7.4%
187	Dermatitis, Irritant	7.4%
188	Acne Conglobata	7.4%
189	Dermatitis, Photoallergic	7.4%
190	Pseudoxanthoma Elasticum	7.3%
191	Tooth Injuries	7.2%
192	Ectodermal Dysplasia	7.2%
193	Aplasia Cutis Congenita	7.2%
194	Maxillary Diseases	6.9%
195	Tooth Resorption	6.9%
196	Sicca Syndrome	6.8%
197	Sjogren's Syndrome	6.8%
198	Toothache	6.7%
199	Erythema Infectiosum	6.7%
200	Dental caries	6.7%
201	Dental Plaque	6.7%
202	Dental Pulp Calcification	6.7%
203	Pulpitis	6.7%
204	Tooth Erosion	6.7%
205	Exanthema Subitum	6.7%
206	Erythema Nodosum	6.6%
207	Acantholysis	6.4%
208	Breast Cyst	6.4%
209	Actinic keratosis	6.4%
210	Pemphigoid, Benign Mucous Membrane	6.4%
211	Pemphigus	6.4%
212	Piedra	6.4%
213	Sunburn	6.4%
214	Argyria	6.3%
215	Hirsutism	6.3%
216	Lactation Disorder	6.3%
217	Mastitis	6.3%
218	Urticaria	6.3%
219	Adiposis Dolorosa	6.2%
220	Pruritus Vulvae	6.2%
221	Mastocytoma	6.2%
222	Pruritus Ani	6.2%
223	Dermatitis, Occupational	6.2%
224	Retrognathia	6.2%
225	Granuloma Annulare	6%
226	Dermatitis, Allergic Contact	5.9%
227	Papillon-Lefevre Disease	5.9%
228	Jaw Abnormalities	5.9%
229	Nasopharyngitis	5.7%
230	Tinea Capitis	5.7%
231	Onychomycosis	5.7%
232	Arthritis, Psoriatic	5.7%
233	Ecthyma	5.6%
234	Pharyngitis	5.6%
235	Prognathism	5.6%
236	Temporomandibular Joint Dysfunction Syndrome	5.2%
237	Collagen Diseases	5.1%
238	Mixed Connective Tissue Disease	5.1%
239	Mucinoses	5.1%
240	Tooth Avulsion	5.1%
241	Dermatomycoses	5.1%
242	Mucocutaneous Lymph Node Syndrome	5.1%
243	Skin Diseases, Bacterial	5.1%
244	Dental Pulp Necrosis	5%
245	Drug Eruptions	5%
246	Lipodystrophy	5%
247	Livedo Reticularis	5%
248	Malignant Atrophic Papulosis	5%
249	Nasopharyngeal Neoplasms	5%
250	Melanosis	5%
251	Chloasma	5%
252	Vitiligo	5%
253	Polyarteritis Nodosa	5%
254	Takayasu Arteritis	5%
255	Ichthyosis, X-Linked	4.9%
256	Sjogren-Larsson Syndrome	4.9%
257	Diaper Rash	4.9%
258	Pharyngeal Neoplasms	4.6%
259	Micrognathism	4.5%
260	Pierre Robin Syndrome	4.5%
261	Maxillofacial Abnormalities	4.5%
262	Albinism	4.4%
263	Erythema Chronicum Migrans	4.3%
264	Nail-Patella Syndrome	4.3%
265	Hyperkeratosis, Epidermolytic	4.3%
266	Hidradenitis Suppurativa	4.2%
267	Porphyrias, Hepatic	4.2%
268	Cartilage Diseases	4%
269	Rheumatism	4%
270	Chondromalacia	4%
271	Tonsillitis	4%
272	Sleep Bruxism	4%
273	Lupus Erythematosus, Systemic	3.9%
274	Overlap syndrome	3.9%
275	Alopecia	3.8%
276	Sweating, Gustatory	3.8%
277	Androgenetic Alopecia	3.8%
278	Auriculotemporal Syndrome	3.8%
279	Lice Infestations	3.7%
280	Varicose Ulcer	3.7%
281	Breast Neoplasms, Male	3.7%
282	Triple Negative Breast Neoplasms	3.7%
283	Galactorrhea	3.7%
284	Nasopharyngeal carcinoma	3.6%
285	Tinea Pedis	3.5%
286	Retropharyngeal Abscess	3.3%
287	Hypopharyngeal Neoplasms	3.3%
288	Hypopharyngeal Cancer	3.3%
289	Lemierre Syndrome	3.3%
290	Acanthosis Nigricans	3.3%
291	Alopecia Areata	3.3%
292	Lentigo	3.3%
293	Mycetoma	3.3%
294	Larva Migrans	3%
295	Leishmaniasis	3%
296	Molluscum Contagiosum	3%
297	Dupuytren Contracture	3%
298	Angioedema	3%
299	Onchocerciasis	3%
300	Chromoblastomycosis	3%
301	Dermatophytosis	3%
302	Sporotrichosis	3%
303	Tinea	3%
304	Tinea Versicolor	3%
305	Trichophytosis	3%
306	Hyalohyphomycosis	3%
307	Acute Generalized Exanthematous Pustulosis	3%
308	Scleromyxedema	2.8%
309	Giant Cell Arteritis	2.7%
310	Temporal Arteritis	2.7%
311	Peritonsillar Abscess	2.7%
312	Tonsillar Neoplasms	2.7%
313	Warts	2.5%
314	Cellulitis	2.5%
315	Candidiasis, Chronic Mucocutaneous	2.5%
316	Cutaneous Candidiasis	2.5%
317	Erysipelas	2.5%
318	Serum Sickness	2.5%
319	Staphylococcal Skin Infections	2.5%
320	Variegate Porphyria	2.5%
321	Acute intermittent porphyria	2.5%
322	Porphyria Cutanea Tarda	2.5%
323	Erythrasma	2.5%
324	Carcinoma, Lobular	2.5%
325	CREST Syndrome	2.4%
326	Mesenteric Panniculitis	2.1%
327	Panniculitis, Peritoneal	2.1%
328	Tietze's Syndrome	2.1%
329	Orbital Cellulitis	2.1%
330	Myxoid cyst	2.1%
331	Myxedema	2.1%
332	Menkes Kinky Hair Syndrome	2%
333	Leishmaniasis, Cutaneous	2%
334	Eczema Herpeticum	2%
335	Fusariosis	2%
336	Noonan Syndrome	1.9%
337	Blastomycosis	1.9%
338	HIV-Associated Lipodystrophy Syndrome	1.8%
339	Osteochondritis	1.7%
340	Polymyalgia Rheumatica	1.7%
341	Marfan Syndrome	1.7%
342	Rhinoscleroma	1.7%
343	Osteogenesis Imperfecta	1.7%
344	Angioedemas, Hereditary	1.7%
345	Keloid	1.7%
346	Epidermodysplasia Verruciformis	1.6%
347	Diabetic Foot	1.6%
348	Homocystinuria	1.6%
349	Staphylococcal Scalded Skin Syndrome	1.6%
350	Basal Cell Nevus Syndrome	1.5%
351	Hereditary Angioedema Type III	1.5%
352	Hereditary Angioedema Types I and II	1.5%
353	Rheumatoid Arthritis	1.4%
354	Juvenile arthritis	1.4%
355	Condylomata Acuminata	1.4%
356	Furunculosis	1.4%
357	furuncle	1.4%
358	Impetigo	1.4%
359	Lupus Nephritis	1.4%
360	Peutz-Jeghers Syndrome	1.2%
361	Laryngomalacia	1.2%
362	Pectus carinatum	1.2%
363	carbuncle	1.2%
364	Rheumatoid Nodule	1%
365	Felty Syndrome	0.8%
366	Bronchomalacia	0.8%
367	Tracheomalacia	0.8%
368	Rheumatoid Vasculitis	0.7%
369	Mucopolysaccharidosis III	0.7%
370	Lupus Vasculitis, Central Nervous System	0.6%
371	Mucopolysaccharidosis II	0.5%

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