MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Glomerulonephritis, Membranoproliferative

(UMLS:C0017662)

Definition:: Chronic glomerulonephritis characterized histologically by proliferation of MESANGIAL CELLS, increase in the MESANGIAL EXTRACELLULAR MATRIX, and a thickening of the glomerular capillary walls. This may appear as a primary disorder or secondary to other diseases including infections and autoimmune disease SYSTEMIC LUPUS ERYTHEMATOSUS. Various subtypes are classified by their abnormal ultrastructures and immune deposits. Hypocomplementemia is a characteristic feature of all types of MPGN.
UMLS ID:: C0017662
MeSH ID:: D015432

Classification 1:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.419.570.363.615

Classification 2:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.419.570.363.615

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.425

Synonym(s)

Glomerulonephritis, Membranoproliferative

GLOMERULONEPHRITIS MEMBRANOPROLIFERATIVE

GLOMERULONEPHRITIS, HYPOCOMPLEMENTEMIC, CHRONIC

GLOMERULONEPHRITIS, MESANGIOCAPILLARY

Glomerulonephritis membranoproliferative

Glomerulonephritis, membranoproliferative

Lobular glomerulonephritis

MCGN - Mesangiocapillary glomerulonephritis

MPGN

10.

MPGN - Membranoproliferative glomerulonephritis

11.

Membranoproliferative Glomerulonephritis

12.

Membranoproliferative glomerulonephritis

13.

Mesangiocapillary Glomerulonephritis

14.

Mesangiocapillary glomerulonephritis

15.

Mesangiocapillary glomerulonephritis, NOS

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Creatine	14725210	CTD
2	Mefenamic Acid	3140090	CTD
3	Methandrostenolone	14725210	CTD
4	Methylprednisolone	18683672	CTD
5	Pentazocine	1316215	CTD
6	Phenytoin	7099337	CTD
7	Prednisolone	18175061	CTD
8	Sirolimus	15112032	CTD
9	Spironolactone	16928621	CTD
10	Tacrolimus	19406543	CTD
11	Tretinoin	17686814	CTD
12	Valsartan	16928621	CTD
13	reviparin	8441232 9111513	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Focal glomerulosclerosis	41.5%
2	Anti-Glomerular Basement Membrane Disease	35.7%
3	Lupus Nephritis	34.4%
4	Nephritis, Interstitial	30.6%
5	Pyelitis	30.6%
6	Pyelonephritis	28.5%
7	Anuria	25.1%
8	Nephrolithiasis	25.1%
9	Hydronephrosis	24.5%
10	Hyperoxaluria	24.5%
11	Kidney Cortex Necrosis	24.5%
12	Kidney Papillary Necrosis	24.5%
13	Nephrosclerosis	24.5%
14	Nephrosis	24.5%
15	Perinephritis	24.5%
16	Kidney Failure	24.5%
17	Uremia	24.5%
18	Oxalosis	24.5%
19	Renal Insufficiency	24.5%
20	Diabetes Insipidus	20.6%
21	Hepatorenal Syndrome	20.6%
22	Diabetic Nephropathy	20.3%
23	Renal hypertension	20.3%
24	Renal Artery Obstruction	20.3%
25	Renal Artery Stenosis	20.3%
26	Balkan Nephropathy	20.3%
27	Nephrocalcinosis	20.2%
28	Urinary Bladder Diseases	20.1%
29	Ureteral Diseases	20.1%
30	Urethral Diseases	20.1%
31	Urination Disorders	20.1%
32	Urolithiasis	20.1%
33	Tuberculosis, Renal	19.9%
34	AIDS-Associated Nephropathy	19.2%
35	Pyelocystitis	18.9%
36	Kidney Neoplasm	17.7%
37	Urinary tract infection	16.9%
38	Ureterolithiasis	15.5%
39	Lipoid nephrosis	14.5%
40	Nephrotic Syndrome	14.5%
41	Pyonephrosis	14.5%
42	Nephrogenic Diabetes Insipidus	14.5%
43	Congenital Nephrogenic Diabetes Insipidus	14.5%
44	Acute kidney injury	14.5%
45	Autoimmune Diseases	14.4%
46	Hypersensitivity	14.4%
47	Immunologic Deficiency Syndromes	14.4%
48	Immunoproliferative Disorders	14.4%
49	Immune reconstitution syndrome	14.4%
50	Immune Reconstitution Inflammatory Syndrome	14.4%
51	Multicystic Dysplastic Kidney	13.9%
52	Kidney Calculi	13.5%
53	Urogenital Abnormalities	12.7%
54	Bladder neck obstruction	12.3%
55	Azotemia	12.2%
56	Hypertension, Renovascular	12%
57	Renal Osteodystrophy	11.9%
58	Renal rickets	11.9%
59	Bladder Exstrophy	11.6%
60	Epispadias	11.6%
61	Transfusion Reaction	11.5%
62	Hypotensive Transfusion Reaction	11.5%
63	Cystitis	11%
64	Ureteral obstruction	11%
65	Ureterocele	11%
66	Urethral Obstruction	11%
67	Urethritis	11%
68	Vesico-Ureteral Reflux	11%
69	Urinary Retention	11%
70	Autoimmune Lymphoproliferative Syndrome	10.8%
71	Immune Complex Diseases	10.4%
72	Antiphospholipid Syndrome	10.4%
73	Latex allergy	10.4%
74	Polycystic Kidney Diseases	10.4%
75	Glycosuria, Renal	10.3%
76	Renal Aminoacidurias	10.3%
77	Fanconi Syndrome	10.3%
78	Pseudohypoaldosteronism	10.3%
79	Liddle Syndrome	10.3%
80	Hemolytic-Uremic Syndrome	10.2%
81	Kidney Failure, Chronic	9.6%
82	Primary amyloidosis	9.6%
83	Ureteral Calculi	9.6%
84	Monoclonal Gammopathy of Undetermined Significance	9.6%
85	Urinary Bladder Fistula	9.4%
86	Bladder Neoplasm	9.4%
87	Ureteral Neoplasms	9.4%
88	Urethral Neoplasms	9.4%
89	Mesoblastic Nephroma	9.3%
90	Renal Cell Carcinoma	9.3%
91	Papillary Renal Cell Carcinoma	9.3%
92	Zellweger Syndrome	9.2%
93	Bacteriuria	9.1%
94	Glycosuria	9.1%
95	Hematuria	9.1%
96	Oliguria	9.1%
97	Polyuria	9.1%
98	Proteinuria	9.1%
99	Pyuria	9.1%
100	Urinary Calculi	9.1%
101	Cystocele	9.1%
102	Urinary Incontinence	9.1%
103	Serum Sickness	9%
104	Renal tubular acidosis	9%
105	Environmental Illness	8.6%
106	anaphylaxis	8.5%
107	Food Allergy	8.5%
108	Anaphylactic shock	8.5%
109	Asthma, Aspirin-Induced	8.4%
110	Lupus Erythematosus, Systemic	8.4%
111	Lymphoproliferative Disorders	8.4%
112	Overlap syndrome	8.4%
113	Addison Disease	8.3%
114	Paraproteinemias	8.3%
115	Pemphigus	8.3%
116	Autoimmune thyroiditis	8.3%
117	Primary Adrenal Insufficiency	8.3%
118	Lymphopenia	8.2%
119	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	8.2%
120	Autoimmune hepatitis	8.2%
121	Autoimmune thrombocytopenia	8%
122	Immune thrombocytopenic purpura	8%
123	Enuresis	7.9%
124	Infertility	7.7%
125	Nephroblastoma	7.7%
126	Genital Diseases, Male	7.6%
127	Milk Allergy	7.6%
128	Schnitzler Syndrome	7.6%
129	Wheat Hypersensitivity	7.6%
130	Sezary Syndrome	7.5%
131	Multiple Myeloma	7.4%
132	Pregnancy Complications	7.4%
133	Hyperphosphaturia	7.1%
134	Respiratory Hypersensitivity	7.1%
135	Hypergammaglobulinemia	6.9%
136	Latent Autoimmune Diabetes in Adults	6.9%
137	Sick Building Syndrome	6.9%
138	Multiple Chemical Sensitivity	6.9%
139	Agammaglobulinemia	6.8%
140	Dermatitis Herpetiformis	6.8%
141	Kounis Syndrome	6.8%
142	Polycystic Kidney, Autosomal Dominant	6.8%
143	HIV Infections	6.8%
144	Transfusion-Related Acute Lung Injury	6.8%
145	Cystinuria	6.8%
146	Plasmacytoma	6.8%
147	Tumor Lysis Syndrome	6.8%
148	Urticaria	6.8%
149	Vasculitis, Leukocytoclastic, Cutaneous	6.8%
150	Thrombocytopenic purpura	6.8%
151	Atypical Hemolytic Uremic Syndrome	6.8%
152	HTLV-I Infections	6.7%
153	Job Syndrome	6.7%
154	Hypospadias	6.7%
155	Myasthenia Gravis, Autoimmune, Experimental	6.6%
156	Urethral Stenosis	6.5%
157	Urethral stricture	6.5%
158	Urologic Neoplasms	6.4%
159	Horseshoe Kidney	6.4%
160	Mastocytosis, Systemic	6%
161	Rheumatoid Arthritis	5.9%
162	Juvenile arthritis	5.9%
163	Graves Disease	5.8%
164	Endometriosis	5.8%
165	Uterine Diseases	5.8%
166	Vaginal Diseases	5.8%
167	Vulvar Diseases	5.8%
168	Endometrioma	5.8%
169	Lymphoma	5.7%
170	Myasthenia Gravis	5.7%
171	Uveomeningoencephalitic Syndrome	5.7%
172	Sexually Transmitted Diseases	5.7%
173	Mastocytosis	5.7%
174	Drug Eruptions	5.6%
175	Chronic granulomatous disease	5.6%
176	Heavy Chain Disease	5.6%
177	Granulomatosis with polyangiitis	5.6%
178	Dermatitis, Allergic Contact	5.6%
179	HIV Seropositivity	5.6%
180	Hermaphroditism	5.5%
181	Disorders of Sex Development	5.5%
182	Genital Herpes	5.5%
183	Albuminuria	5.4%
184	Hemoglobinuria	5.4%
185	Urge Incontinence	5.4%
186	Neuromyelitis Optica	5.3%
187	Leukoencephalitis, Acute Hemorrhagic	5.2%
188	Genital Neoplasms, Male	5.2%
189	Angioedema	5.1%
190	Multiple Sclerosis	5%
191	Hodgkin Disease	5%
192	Leukemia, Plasma Cell	5%
193	Lymphoma, Non-Hodgkin	5%
194	Leukemia, T-Cell	5%
195	Acute Generalized Exanthematous Pustulosis	5%
196	Leukemia, B-Cell	5%
197	Stiff-Person Syndrome	4.9%
198	Polyradiculoneuropathy	4.9%
199	Polyradiculoneuritis	4.9%
200	Acquired Immunodeficiency Syndrome	4.8%
201	AIDS related complex	4.8%
202	Infectious Mononucleosis	4.8%
203	Cryoglobulinemia	4.8%
204	Felty Syndrome	4.8%
205	POEMS Syndrome	4.8%
206	Asthma, Exercise-Induced	4.8%
207	Status Asthmaticus	4.8%
208	Multiple Sclerosis, Chronic Progressive	4.7%
209	Multiple Sclerosis, Relapsing-Remitting	4.7%
210	Lymphoma, Follicular	4.7%
211	T-Cell Lymphoma	4.7%
212	Mantle cell lymphoma	4.7%
213	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	4.7%
214	Leukemia, Large Granular Lymphocytic	4.7%
215	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	4.7%
216	Diurnal Enuresis	4.6%
217	Genital Neoplasms, Female	4.6%
218	Hereditary Angioedema Type III	4.5%
219	Hereditary Angioedema Types I and II	4.5%
220	Lymphoma, T-Cell, Cutaneous	4.5%
221	Lymphoma, AIDS-Related	4.5%
222	Enteropathy-Associated T-Cell Lymphoma	4.5%
223	Primary Effusion Lymphoma	4.5%
224	Kernicterus	4.5%
225	Denys-Drash Syndrome	4.5%
226	Lupus Vasculitis, Central Nervous System	4.5%
227	Mycosis Fungoides	4.4%
228	Lymphomatoid Papulosis	4.4%
229	Plasmablastic lymphoma	4.4%
230	Hydrops Fetalis	4.4%
231	Asthma	4.4%
232	Composite Lymphoma	4.3%
233	Encephalomyelitis, Acute Disseminated	4.3%
234	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	4.3%
235	Erythema Nodosum	4.3%
236	Neuritis, Autoimmune, Experimental	4.3%
237	Dermatitis, Photoallergic	4.3%
238	Lymphangioleiomyomatosis	4.3%
239	AIDS-Related Opportunistic Infections	4.3%
240	Vasculitis, Central Nervous System	4.2%
241	Dermatitis, Atopic	4.2%
242	Asthma, Occupational	4.2%
243	HIV Wasting Syndrome	4.2%
244	Rheumatoid Vasculitis	4.2%
245	Uterine Neoplasms	4.2%
246	Vaginal Neoplasms	4.2%
247	Vulvar Neoplasms	4.2%
248	Uterine Cancer	4.2%
249	AIDS Dementia Complex	4.2%
250	Farmer's Lung	4.1%
251	Angioedemas, Hereditary	4.1%
252	Ataxia Telangiectasia	4.1%
253	Uterine Inversion	4%
254	Hay fever	4%
255	Rhinitis, Allergic, Perennial	4%
256	Endometritis	4%
257	Vesicovaginal Fistula	4%
258	Lymphomatoid Granulomatosis	3.9%
259	Epididymitis	3.9%
260	Penile Diseases	3.9%
261	Prostatic Diseases	3.9%
262	Spermatic Cord Torsion	3.9%
263	Hemospermia	3.9%
264	Testicular Hydrocele	3.9%
265	Aspergillosis, Allergic Bronchopulmonary	3.8%
266	Lambert-Eaton Myasthenic Syndrome	3.8%
267	Guillain-Barre Syndrome	3.8%
268	Waldenstrom Macroglobulinemia	3.7%
269	Wiskott-Aldrich Syndrome	3.7%
270	Sicca Syndrome	3.7%
271	Sjogren's Syndrome	3.7%
272	Polyhydramnios	3.7%
273	Obstetric Labor Complications	3.7%
274	Ectopic Pregnancy	3.7%
275	Pregnancy, Prolonged	3.7%
276	Puerperal Disorders	3.7%
277	Oligohydramnios	3.7%
278	Prenatal Injuries	3.7%
279	HIV-Associated Lipodystrophy Syndrome	3.7%
280	Penile Neoplasms	3.6%
281	Prostatic Neoplasms	3.6%
282	Dyspareunia	3.5%
283	Cryptorchidism	3.4%
284	Uterine Rupture	3.4%
285	Burkitt Lymphoma	3.4%
286	Fallopian Tube Neoplasms	3.3%
287	Toxic Epidermal Necrolysis	3.3%
288	Stevens-Johnson Syndrome	3.3%
289	Endometrial Hyperplasia	3.2%
290	Pyometra	3.2%
291	Vaginitis	3.2%
292	Vulvitis	3.2%
293	Vaginal Discharge	3.2%
294	Vulvodynia	3.2%
295	Testicular Diseases	3.1%
296	Varicocele	3.1%
297	Familial Hypophosphatemic Rickets	3.1%
298	Spermatocele	3.1%
299	Abruptio Placentae	3.1%
300	Placenta Accreta	3.1%
301	Fetal Diseases	3.1%
302	Pregnancy Complications, Cardiovascular	3.1%
303	Pregnancy Complications, Neoplastic	3.1%
304	Salpingitis	3%
305	Vulvovaginitis	3%
306	Gonadal Dysgenesis	3%
307	Adrenogenital Syndrome	3%
308	Ovotesticular Disorders of Sex Development	3%
309	Giant Cell Arteritis	3%
310	Temporal Arteritis	3%
311	Pregnancy Complications, Hematologic	3%
312	Pregnancy Complications, Infectious	3%
313	Fetal Death	2.9%
314	Perinatal death	2.9%
315	Morning Sickness	2.9%
316	Chorioamnionitis	2.8%
317	Myelitis, Transverse	2.7%
318	Ovarian Diseases	2.6%
319	Miller Fisher Syndrome	2.6%
320	Puerperal Infection	2.5%
321	Adnexitis	2.5%
322	Pruritus Vulvae	2.5%
323	Uterine hemorrhage	2.5%
324	Vaginal Fistula	2.5%
325	Pelvic Inflammatory Disease	2.5%
326	Postpartum Hemorrhage	2.5%
327	ovarian neoplasm	2.5%
328	Uterine Prolapse	2.5%
329	Vaginal Prolapse	2.5%
330	Oophoritis	2.5%
331	Endometrial Neoplasms	2.5%
332	Gestational Diabetes	2.4%
333	Uterine Cervical Incompetence	2.3%
334	Hyperandrogenism	2.2%
335	Balanitis	2.1%
336	Benign prostatic hypertrophy	2.1%
337	Phimosis	2.1%
338	Priapism	2.1%
339	prostatitis	2.1%
340	Prostatic Adenoma	2.1%
341	Benign Prostatic Hyperplasia	2.1%
342	Prostatic Hypertrophy	2.1%
343	Prostatic Hyperplasia	2.1%
344	Prostatic Neoplasms, Castration-Resistant	2.1%
345	Abortion, Habitual	1.9%
346	Dystocia	1.9%
347	Eclampsia	1.9%
348	Fetal Membranes, Premature Rupture	1.9%
349	Placental Insufficiency	1.9%
350	Pre-Eclampsia	1.9%
351	Prenatal Exposure Delayed Effects	1.9%
352	HELLP Syndrome	1.9%
353	Placenta, Retained	1.9%
354	Carcinoma, Endometrioid	1.9%
355	Uterine Cervicitis	1.9%
356	Leukorrhea	1.9%
357	Parametritis	1.9%
358	Testicular Neoplasms	1.9%
359	Premature Ejaculation	1.7%
360	Erectile dysfunction	1.7%
361	Orchitis	1.7%
362	Candidiasis, Vulvovaginal	1.7%
363	Abortion, Veterinary	1.6%
364	Pregnancy Complications, Parasitic	1.6%
365	Chlamydia Infections	1.6%
366	Gonorrhea	1.6%
367	Bacterial Vaginosis	1.5%
368	Lactation Disorder	1.5%
369	Mastitis	1.5%
370	Depression, Postpartum	1.5%
371	Embryo Loss	1.5%
372	Turner Syndrome	1.5%
373	Fetal Resorption	1.5%
374	Hyperemesis Gravidarum	1.5%
375	Trichomonas Vaginitis	1.5%
376	Uterine Perforation	1.5%
377	Ovarian Hyperstimulation Syndrome	1.5%
378	Metrorrhagia	1.5%
379	Kallmann Syndrome	1.4%
380	Syphilis	1.4%
381	granulosa cell tumor	1.4%
382	Carcinoma, Ovarian Epithelial	1.4%
383	Fetal Growth Retardation	1.3%
384	Trophoblastic Neoplasms	1.3%
385	Embolism, Amniotic Fluid	1.3%
386	Fetal Hypoxia	1.3%
387	Fetal Alcohol Spectrum Disorders	1.3%
388	Corpus Luteum Cyst	1.3%
389	Ovarian Cysts	1.3%
390	Azoospermia	1.3%
391	Oligospermia	1.3%
392	Impotence, Vasculogenic	1.3%
393	Asthenozoospermia	1.3%
394	Teratozoospermia	1.3%
395	Aspermia	1.3%
396	Breech Presentation	1.3%
397	Anovulation	1.3%
398	Menorrhagia	1.3%
399	Stillbirth	1.3%
400	Premature Menopause	1.2%
401	Klinefelter Syndrome	1.2%
402	Endometrial Stromal Sarcoma	1.1%
403	Premature Birth	1.1%
404	Lymphogranuloma Venereum	1%
405	Meconium Aspiration Syndrome	1%
406	Galactorrhea	0.8%
407	Polycystic Ovary Syndrome	0.8%
408	Leydig Cell Tumor	0.7%
409	Choriocarcinoma	0.6%
410	Hydatidiform Mole	0.4%

Page last updated at 2020-05-25 10:01:57 (Asia/Shanghai) | You are visitor No. 120240