MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Orbital Cellulitis

(UMLS:C0149507)

Definition:: Inflammation of the loose connective tissues around the ORBIT, bony structure around the eyeball. It is characterized by PAIN; EDEMA of the CONJUNCTIVA; swelling of the EYELIDS; EXOPHTHALMOS; limited eye movement; and loss of vision.
UMLS ID:: C0149507
MeSH ID:: D054517

Classification 1:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.675.387

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.185.500

Synonym(s)

Orbital Cellulitis

Cellulitis orbital

Orbital cellulitis

Postseptal orbital cellulitis

cellulitis orbital

cellulitis; orbit

orbit; cellulitis

orbital cellulitis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Cocaine		10604666 19458577	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Enophthalmos	27.9%
2	Exophthalmos	27.9%
3	Orbital Pseudotumor	27.9%
4	Lupus Erythematosus, Cutaneous	21.1%
5	Panniculitis	21.1%
6	Systemic Scleroderma	21.1%
7	Morphea	21.1%
8	Collagen Diseases	20.9%
9	Mixed Connective Tissue Disease	20.9%
10	Mucinoses	20.9%
11	Retrobulbar Hemorrhage	20.7%
12	Cartilage Diseases	16.4%
13	Rheumatism	16.4%
14	Chondromalacia	16.4%
15	Orbital Myositis	16.3%
16	Lupus Erythematosus, Systemic	15.8%
17	Overlap syndrome	15.8%
18	Panniculitis, Lupus Erythematosus	15.6%
19	Cutis Laxa	15.1%
20	Asthenopia	14.6%
21	Conjunctival Diseases	14.6%
22	Corneal Diseases	14.6%
23	Eyelid Diseases	14.6%
24	Lacrimal Apparatus Diseases	14.6%
25	Lens Diseases	14.6%
26	Ocular Hypertension	14.6%
27	Ocular Hypotension	14.6%
28	Retinal Diseases	14.6%
29	Scleral Diseases	14.6%
30	Vitreous Detachment	14.6%
31	Posterior Vitreous Detachment	14.6%
32	Retinal Degeneration	14%
33	Scleromyxedema	13.6%
34	Dermatomyositis	13.6%
35	Lupus Erythematosus, Discoid	13.6%
36	Scleroderma, Limited	13.6%
37	Dupuytren Contracture	12.2%
38	Xerophthalmia	12.1%
39	Low Tension Glaucoma	12.1%
40	Iridocorneal endothelial syndrome	12.1%
41	Retinal Dysplasia	11.9%
42	Blepharophimosis	11.1%
43	Uveal Neoplasms	11.1%
44	Eyelid Neoplasms	11%
45	Retinal Hemorrhage	11%
46	Eye Abnormalities	10.9%
47	Eye Infection	10.9%
48	Eye Manifestations	10.9%
49	Eye Neoplasms	10.9%
50	Optic Neuropathy	10.9%
51	Aniridia	10.8%
52	Keratoconjunctivitis Sicca	10.7%
53	Mesenteric Panniculitis	10.3%
54	Panniculitis, Peritoneal	10.3%
55	Pemphigoid, Benign Mucous Membrane	10.3%
56	Tietze's Syndrome	10.3%
57	Myxoid cyst	10.3%
58	Graves Disease	10.2%
59	Keratoconjunctivitis	10.2%
60	Myxedema	10.2%
61	Chorioretinitis	10.1%
62	Pseudoxanthoma Elasticum	9.7%
63	Corneal Ulcer	9.6%
64	Choroid Hemorrhage	9.5%
65	Necrobiosis Lipoidica Diabeticorum	9.5%
66	Pars Planitis	9.4%
67	Angioid Streaks	9.3%
68	Anisometropia	9.3%
69	Aphakia	9.3%
70	Astigmatism	9.3%
71	Blepharitis	9.3%
72	Blepharoptosis	9.3%
73	Blepharospasm	9.3%
74	Choroid Diseases	9.3%
75	Conjunctivitis	9.3%
76	Corneal edema	9.3%
77	Corneal Opacity	9.3%
78	Dacryocystitis	9.3%
79	Dry Eye Syndromes	9.3%
80	Ectropion	9.3%
81	Entropion	9.3%
82	Episcleritis	9.3%
83	Glaucoma	9.3%
84	Iris Diseases	9.3%
85	Keratitis	9.3%
86	Keratoconus	9.3%
87	Lacrimal Duct Obstruction	9.3%
88	Lens dislocation	9.3%
89	Lens Subluxation	9.3%
90	Mydriasis	9.3%
91	Myopia	9.3%
92	Presbyopia	9.3%
93	Pterygium	9.3%
94	Retinal Detachment	9.3%
95	Retinitis	9.3%
96	Scleritis	9.3%
97	Uveitis	9.3%
98	Corneal Neovascularization	9.3%
99	Cataract	9.3%
100	Pinguecula	9.3%
101	Trichiasis	9.3%
102	Duane Retraction Syndrome	9.2%
103	Corneal Scar	9%
104	Retinitis Pigmentosa	8.8%
105	Pigmentary retinopathy	8.8%
106	Choroiditis	8.8%
107	Iridocyclitis	8.8%
108	Iritis	8.8%
109	Granuloma Annulare	8.7%
110	Ocular Motility Disorders	8.7%
111	Cyclophoria	8.7%
112	Pupil Disorders	8.6%
113	Eye Hemorrhage	8.5%
114	Vision Disorders	8.4%
115	Metamorphopsia	8.4%
116	Visual Impairment	8.4%
117	Eye Injuries	8.3%
118	Osteochondritis	8.3%
119	Polymyalgia Rheumatica	8.3%
120	Erythema Induratum	8.2%
121	Osteogenesis Imperfecta	8.2%
122	Pyoderma Gangrenosum	8.1%
123	Keloid	8%
124	Hordeolum	7.9%
125	Color blindness	7.8%
126	Noonan Syndrome	7.6%
127	Trachoma	7.4%
128	Retinoblastoma	7.4%
129	Breast Diseases	7%
130	Dermatitis	7%
131	Exanthema	7%
132	Facial Dermatoses	7%
133	Hair Diseases	7%
134	Hand Dermatoses	7%
135	keratoacanthoma	7%
136	Keratosis	7%
137	Nail Diseases	7%
138	Photosensitivity Disorders	7%
139	Prurigo	7%
140	Pyoderma	7%
141	Rosacea	7%
142	Sebaceous Gland Diseases	7%
143	Skin Diseases, Vesiculobullous	7%
144	Skin Ulcer	7%
145	Sweat Gland Diseases	7%
146	Skin Diseases, Papulosquamous	7%
147	Skin Diseases, Vascular	7%
148	Acneiform Eruptions	7%
149	Ocular Rosacea	7%
150	Subcorneal pustular dermatosis	7%
151	Erythematotelangiectatic Rosacea	7%
152	Papulopustular Rosacea	7%
153	Chronic Actinic Dermatitis	7%
154	Anophthalmos	6.9%
155	Rheumatoid Arthritis	6.9%
156	Endophthalmitis	6.9%
157	Microphthalmos	6.9%
158	Optic Atrophy	6.9%
159	Optic Neuritis	6.9%
160	Papilledema	6.9%
161	Retinal Artery Occlusion	6.9%
162	Retinopathy of Prematurity	6.9%
163	Strabismus	6.9%
164	Tolosa-Hunt Syndrome	6.9%
165	Retinal Vasculitis	6.9%
166	Hypertensive Retinopathy	6.9%
167	Corneal Endothelial Cell Loss	6.9%
168	Juvenile arthritis	6.9%
169	Hyphema	6.8%
170	Retinal Neovascularization	6.8%
171	Vitreous Hemorrhage	6.8%
172	Acanthamoeba Keratitis	6.8%
173	Angle Closure Glaucoma	6.8%
174	Glaucoma, Open-Angle	6.8%
175	Macular degeneration	6.8%
176	Panuveitis	6.8%
177	Retinal Drusen	6.8%
178	Retinal Necrosis Syndrome, Acute	6.8%
179	Retinoschisis	6.8%
180	Exfoliation Syndrome	6.8%
181	Marfan Syndrome	6.8%
182	Acne Vulgaris	6.8%
183	Contact Dermatitis	6.8%
184	Eczema	6.8%
185	Erythema Multiforme	6.8%
186	Keratitis, Herpetic	6.8%
187	Intertrigo	6.8%
188	Neurodermatitis	6.8%
189	Rhinophyma	6.8%
190	Cytomegalovirus Retinitis	6.8%
191	Perioral Dermatitis	6.8%
192	Acne	6.8%
193	Bacterial conjunctivitis	6.7%
194	Lupus Nephritis	6.6%
195	Corneal Perforation	6.6%
196	Homocystinuria	6.6%
197	Sicca Syndrome	6.2%
198	Sjogren's Syndrome	6.2%
199	Rheumatoid Nodule	6%
200	Dermatitis, Phototoxic	6%
201	Pityriasis Lichenoides et Varioliformis Acuta	6%
202	Pityriasis Lichenoides	6%
203	Phototoxicity	6%
204	Laryngomalacia	5.9%
205	Foot Ulcer	5.9%
206	Pectus carinatum	5.9%
207	Dermatitis, Atopic	5.8%
208	Epidermolysis Bullosa	5.8%
209	Anterior uveitis	5.6%
210	Uveitis, Posterior	5.6%
211	Albinism	5.6%
212	Optic Neuropathy, Ischemic	5.6%
213	Anterior Ischemic Optic Neuropathy	5.6%
214	Retinal Vein Occlusion	5.5%
215	Dermatitis Herpetiformis	5.5%
216	Foot Diseases	5.5%
217	Anisocoria	5.4%
218	Diabetic Retinopathy	5.4%
219	Tonic Pupil	5.4%
220	Eye pain	5.4%
221	Panophthalmitis	5.4%
222	Acrodermatitis	5.4%
223	Sebaceous Gland Neoplasms	5.4%
224	Xeroderma Pigmentosum	5.4%
225	Porokeratosis	5.4%
226	Gianotti-Crosti Syndrome	5.4%
227	Keratoderma, Palmoplantar	5.4%
228	Diplopia	5.4%
229	Scotoma	5.4%
230	Photophobia	5.4%
231	Amaurosis	5.4%
232	Blindness	5.4%
233	Skin Abnormalities	5.3%
234	Skin Diseases, Infectious	5.3%
235	Skin Neoplasms	5.3%
236	Pigmentation Disorders	5.3%
237	Lipomatosis	5.2%
238	Pruritus	5.2%
239	Erythema	5.2%
240	Necrolytic Migratory Erythema	5.2%
241	Cutaneous Fistula	5.2%
242	Nephrogenic Fibrosing Dermopathy	5.2%
243	Nephrogenic Systemic Fibrosis	5.2%
244	Esotropia	5%
245	Exotropia	5%
246	Choroidal Neovascularization	5%
247	Felty Syndrome	5%
248	Dermatitis, Irritant	5%
249	Acne Conglobata	5%
250	Bronchomalacia	5%
251	Tracheomalacia	5%
252	Dermatitis, Photoallergic	4.9%
253	CREST Syndrome	4.9%
254	Behcet Syndrome	4.8%
255	Urticaria Pigmentosa	4.6%
256	Anhidrosis	4.5%
257	Cholesteatoma	4.5%
258	Pressure Ulcer	4.5%
259	Folliculitis	4.5%
260	Foot Dermatoses	4.5%
261	Gynecomastia	4.5%
262	Hypertrichosis	4.5%
263	Hypohidrosis	4.5%
264	Hypotrichosis	4.5%
265	Leg Ulcer	4.5%
266	Miliaria	4.5%
267	Parakeratosis	4.5%
268	Parapsoriasis	4.5%
269	Pityriasis	4.5%
270	Psoriasis	4.5%
271	Xeroderma	4.5%
272	Sweet Syndrome	4.5%
273	Hidradenitis	4.5%
274	Onycholysis	4.5%
275	Miliaria Rubra	4.5%
276	Hyperpigmentation	4.5%
277	Lichenoid Eruptions	4.5%
278	Chloracne	4.5%
279	Ophthalmoplegia	4.5%
280	External Ophthalmoplegia	4.5%
281	Amblyopia	4.5%
282	Rheumatoid Vasculitis	4.3%
283	Mucopolysaccharidosis III	4.2%
284	Dermatitis, Occupational	4.2%
285	Diaper Rash	4.1%
286	Ophthalmia Neonatorum	4.1%
287	Uveomeningoencephalitic Syndrome	4.1%
288	CHARGE Syndrome	4.1%
289	Mastocytosis	4.1%
290	Congenital nystagmus	4.1%
291	Herpes Zoster Ophthalmicus	4.1%
292	Optic Atrophy, Hereditary, Leber	4%
293	Dermatitis, Allergic Contact	4%
294	Hemianopsia	4%
295	Papillon-Lefevre Disease	4%
296	Amaurosis Fugax	4%
297	Blindness, Cortical	4%
298	Erythema Infectiosum	4%
299	Exanthema Subitum	3.9%
300	Erythema Nodosum	3.9%
301	Ectodermal Dysplasia	3.8%
302	Aplasia Cutis Congenita	3.8%
303	Toxic Epidermal Necrolysis	3.7%
304	Stevens-Johnson Syndrome	3.7%
305	Tinea Capitis	3.6%
306	Onychomycosis	3.6%
307	Acantholysis	3.4%
308	Breast Cyst	3.4%
309	Actinic keratosis	3.4%
310	Pemphigus	3.4%
311	Piedra	3.4%
312	Sunburn	3.4%
313	Aicardi's syndrome	3.4%
314	Argyria	3.4%
315	Hirsutism	3.4%
316	Lactation Disorder	3.4%
317	Mastitis	3.4%
318	Urticaria	3.4%
319	Lichen Planus	3.4%
320	Melanosis	3.4%
321	Chloasma	3.4%
322	Pityriasis Rosea	3.4%
323	Pityriasis Rubra Pilaris	3.4%
324	Vitiligo	3.4%
325	Lichen Nitidus	3.4%
326	Adiposis Dolorosa	3.4%
327	Horner Syndrome	3.4%
328	Pruritus Vulvae	3.4%
329	Mastocytoma	3.3%
330	Pruritus Ani	3.3%
331	Ecthyma	3.3%
332	Mandibulofacial Dysostosis	3.3%
333	Hyperkeratosis, Epidermolytic	3.3%
334	Lupus Vasculitis, Central Nervous System	3%
335	Ichthyosis, X-Linked	3%
336	Sjogren-Larsson Syndrome	3%
337	Opsoclonus-Myoclonus Syndrome	3%
338	Mucopolysaccharidosis II	2.9%
339	Hidradenitis Suppurativa	2.8%
340	Acanthosis Nigricans	2.8%
341	Alopecia Areata	2.8%
342	Lentigo	2.8%
343	Dermatomycoses	2.7%
344	Mucocutaneous Lymph Node Syndrome	2.7%
345	Skin Diseases, Bacterial	2.7%
346	Drug Eruptions	2.7%
347	Lipodystrophy	2.7%
348	Livedo Reticularis	2.7%
349	Malignant Atrophic Papulosis	2.7%
350	Polyarteritis Nodosa	2.7%
351	Takayasu Arteritis	2.7%
352	Miller Fisher Syndrome	2.6%
353	Kearns-Sayre syndrome	2.6%
354	Tinea Pedis	2.6%
355	Alopecia	2.6%
356	Sweating, Gustatory	2.6%
357	Androgenetic Alopecia	2.6%
358	Auriculotemporal Syndrome	2.6%
359	Erythema Chronicum Migrans	2.6%
360	Lice Infestations	2.5%
361	Varicose Ulcer	2.5%
362	Breast Neoplasms, Male	2.5%
363	Triple Negative Breast Neoplasms	2.5%
364	Galactorrhea	2.5%
365	Nail-Patella Syndrome	2.3%
366	Porphyrias, Hepatic	2.3%
367	Ophthalmoplegic Migraine	2.2%
368	Progressive supranuclear palsy	2.2%
369	Mycetoma	2.2%
370	Lichen Planus, Oral	2.1%
371	Larva Migrans	2%
372	Leishmaniasis	2%
373	Molluscum Contagiosum	2%
374	Angioedema	2%
375	Onchocerciasis	2%
376	Chromoblastomycosis	2%
377	Dermatophytosis	2%
378	Sporotrichosis	2%
379	Tinea	2%
380	Tinea Versicolor	2%
381	Trichophytosis	2%
382	Hyalohyphomycosis	2%
383	Acute Generalized Exanthematous Pustulosis	2%
384	Neuromyelitis Optica	2%
385	Alstrom Syndrome	1.8%
386	Warts	1.7%
387	Candidiasis, Chronic Mucocutaneous	1.7%
388	Cutaneous Candidiasis	1.7%
389	Leishmaniasis, Cutaneous	1.7%
390	Eczema Herpeticum	1.7%
391	Erysipelas	1.7%
392	Serum Sickness	1.7%
393	Staphylococcal Skin Infections	1.7%
394	Variegate Porphyria	1.7%
395	Acute intermittent porphyria	1.7%
396	Porphyria Cutanea Tarda	1.7%
397	Erythrasma	1.7%
398	Carcinoma, Lobular	1.7%
399	Arthritis, Psoriatic	1.6%
400	Fusariosis	1.6%
401	Optic Nerve Glioma	1.6%
402	Hereditary Angioedema Type III	1.5%
403	Hereditary Angioedema Types I and II	1.5%
404	Giant Cell Arteritis	1.5%
405	Temporal Arteritis	1.5%
406	Angioedemas, Hereditary	1.4%
407	Epidermodysplasia Verruciformis	1.4%
408	Herpes Labialis	1.4%
409	Diabetic Foot	1.4%
410	Staphylococcal Scalded Skin Syndrome	1.4%
411	Peutz-Jeghers Syndrome	1.3%
412	Blastomycosis	1.3%
413	HIV-Associated Lipodystrophy Syndrome	1.2%
414	carbuncle	1.2%
415	Condylomata Acuminata	1.2%
416	Furunculosis	1.2%
417	furuncle	1.2%
418	Impetigo	1.2%
419	Rhinoscleroma	1.1%
420	Menkes Kinky Hair Syndrome	1.1%

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