MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Lemierre Syndrome

(UMLS:C0343525)

Definition:: A superinfection of the damaged oropharyngeal mucosa by FUSOBACTERIUM NECROPHORUM leading to the secondary septic THROMBOPHLEBITIS of the internal jugular vein.
UMLS ID:: C0343525
MeSH ID:: D057831

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.252.400.388.350.700

Classification 2:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.550.174

Classification 3:

Name:

Otorhinolaryngologic Diseases
MeSH Tree Number(s):: C09.775.262

Classification 4:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.355.830.925.770.500|C14.907.617.718.788.500|C14.907.940.740.910.500

Synonym(s)

Lemierre Syndrome

Fusobacterial necrotising tonsillitis

Fusobacterial necrotizing tonsillitis

Lemierre syndrome

Lemierre's syndrome

tonsillitis fusobacterial necrotizing

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Voriconazole	FAERS: 4	US FAERS
2	Norgestrel	FAERS: 3	US FAERS
3	Prednisolone	FAERS: 2	US FAERS
4	Clindamycin	FAERS: 1	US FAERS
5	Ibuprofen	FAERS: 1	US FAERS
6	Rivaroxaban	FAERS: 1	US FAERS
7	prednisolone phosphate	FAERS: 1	US FAERS
8	Tobramycin		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Retinal Vein Occlusion	25.6%
2	Myocardial Ischemia	22.2%
3	Aortitis	22.1%
4	Thromboangiitis Obliterans	22.1%
5	Nasopharyngitis	21.7%
6	Postphlebitic Syndrome	21.6%
7	Nasopharyngeal Neoplasms	21.4%
8	Malignant Atrophic Papulosis	19.7%
9	Shwartzman Phenomenon	19.6%
10	Aneurysm	18.9%
11	Angiomatosis	18.9%
12	Aortic Diseases	18.9%
13	Arterial Occlusive Diseases	18.9%
14	Hyperemia	18.9%
15	Hypotension	18.9%
16	Superior Vena Cava Syndrome	18.9%
17	Telangiectasis	18.9%
18	Venous Insufficiency	18.9%
19	Angiodysplasia	18.9%
20	Capillary Leak Syndrome	18.9%
21	Prehypertension	18.9%
22	Pharyngeal Neoplasms	18.8%
23	Pharyngitis	18%
24	Aortic Aneurysm	18%
25	Leriche Syndrome	18%
26	Myocardial Reperfusion Injury	17.4%
27	Vascular System Injuries	17%
28	Compartment syndromes	16.7%
29	Hepatic Veno-Occlusive Disease	16.7%
30	Peliosis Hepatis	16.7%
31	Varicocele	16.7%
32	Cerebrovascular Disorders	16.5%
33	Diabetic Angiopathies	16.5%
34	Reperfusion Injury	16.5%
35	Splenic Infarction	16.5%
36	Cerebrovascular Insufficiency	16.5%
37	Vascular Neoplasms	16.5%
38	Spinal Cord Vascular Diseases	16.5%
39	Vasoplegia	16.5%
40	Hemorrhoids	16.5%
41	Thoracic Outlet Syndrome	16.5%
42	Blue Toe Syndrome	16.3%
43	Coronary Thrombosis	16.3%
44	Nasopharyngeal carcinoma	16.3%
45	Vasculitis, Central Nervous System	16.2%
46	Hand-Arm Vibration Syndrome	15%
47	Arteritis	15%
48	Erythromelalgia	15%
49	Raynaud Disease	15%
50	Systemic Vasculitis	15%
51	Optic Neuropathy, Ischemic	14.8%
52	Anterior Ischemic Optic Neuropathy	14.8%
53	Mesenteric vascular insufficiency	14.8%
54	Ulcerative stomatitis	14.6%
55	Angioedema	14.6%
56	Colitis, Ischemic	14.6%
57	Embolism	14.5%
58	Thromboembolism	14.5%
59	Embolus	14.5%
60	Intracranial Embolism and Thrombosis	14.4%
61	May-Thurner Syndrome	14.3%
62	Arteriovenous fistula	14.2%
63	Coronary Aneurysm	14.1%
64	Hypopharyngeal Neoplasms	13.8%
65	Hypopharyngeal Cancer	13.8%
66	Polyarteritis Nodosa	13.7%
67	Tonsillitis	13.2%
68	Retinal Vasculitis	13.2%
69	Scimitar Syndrome	13.2%
70	Vasculitis, Leukocytoclastic, Cutaneous	13.1%
71	Embolism and Thrombosis	12.8%
72	Moyamoya Disease	12.6%
73	Giant Cell Arteritis	12.6%
74	Temporal Arteritis	12.6%
75	Aortic Rupture	12.6%
76	Carotid Stenosis	12.6%
77	Intracranial Aneurysm	12.6%
78	Vasculitis	12.5%
79	Peripheral Vascular Diseases	12.5%
80	Retropharyngeal Abscess	12.4%
81	Heart Diseases	12.2%
82	Bacterial Endocarditis	12.2%
83	Hepatic Vein Thrombosis	12.1%
84	Budd-Chiari Syndrome	12.1%
85	Coronary heart disease	12%
86	Myocardial Infarction	12%
87	Acute Coronary Syndrome	12%
88	Carotid Artery Thrombosis	12%
89	Periphlebitis	11.8%
90	Phlebitis	11.8%
91	Mucocutaneous Lymph Node Syndrome	11.7%
92	Livedo Reticularis	11.7%
93	Takayasu Arteritis	11.5%
94	Embolism, Amniotic Fluid	11.4%
95	Tonsillar Neoplasms	11.4%
96	CREST Syndrome	11%
97	Behcet Syndrome	11%
98	Coronary Artery Disease	10.8%
99	Pregnancy Complications, Cardiovascular	10.8%
100	Cardiovascular Abnormalities	10.8%
101	Kounis Syndrome	10.7%
102	Angina Pectoris	10.6%
103	Aortic Aneurysm, Abdominal	10.4%
104	Aortic Aneurysm, Thoracic	10.4%
105	Borrelia Infections	10.3%
106	Leptospirosis	10.3%
107	Peritonsillar Abscess	10.3%
108	Aneurysm, Dissecting	10.2%
109	Arteriosclerosis	10.2%
110	Fibromuscular Dysplasia	10.2%
111	Malignant Hypertension	10.2%
112	Essential Hypertension	10.2%
113	Aneurysm, Ruptured	10.2%
114	Iliac Aneurysm	10.2%
115	Pulmonary artery stenosis	10.2%
116	White Coat Hypertension	10.2%
117	Deglutition Disorders	10%
118	Lyme Disease	9.3%
119	Relapsing Fever	9.3%
120	Intracranial Arteriosclerosis	9.2%
121	Cerebral Atherosclerosis	9.2%
122	Cerebral Arteriosclerosis	9.2%
123	Retinal Artery Occlusion	9.1%
124	Hypertensive Retinopathy	9.1%
125	Anterior Compartment Syndrome	9%
126	Gastric Antral Vascular Ectasia	9%
127	Abdominal Compartment Syndrome	9%
128	Carotid Artery Diseases	8.9%
129	Brain Ischemia	8.9%
130	Hypotension, Orthostatic	8.9%
131	Cerebrovascular accident	8.9%
132	Varicose Ulcer	8.9%
133	Vasospasm, Intracranial	8.9%
134	Spinal Cord Ischemia	8.9%
135	Intracranial Arterial Diseases	8.9%
136	Primary Graft Dysfunction	8.9%
137	Post-Exercise Hypotension	8.9%
138	Endarteritis	8.8%
139	Cerebral Thrombosis	8.7%
140	Intracranial Embolism	8.7%
141	Intracranial Thrombosis	8.7%
142	Human Ehrlichiosis	8.6%
143	Air Embolism	8.3%
144	Venous Thromboembolism	8.3%
145	Brain Infarction	8.3%
146	Bordetella Infections	8.2%
147	Brucellosis	8.2%
148	Campylobacter infection	8.2%
149	Enterobacteriaceae Infections	8.2%
150	Pseudomonas Infections	8.2%
151	Q Fever	8.2%
152	Vibrio Infections	8.2%
153	Helicobacter Infections	8.2%
154	Neisseriaceae Infections	8.2%
155	Burkholderia Infections	8.2%
156	Flavobacteriaceae Infections	8.2%
157	Moraxellaceae Infections	8.2%
158	Burkholderia cepacia Infection	8.2%
159	Thrombophlebitis	8.2%
160	Mesenteric Vascular Occlusion	8%
161	Diabetic Retinopathy	8%
162	Sturge-Weber Syndrome	8%
163	Renal hypertension	8%
164	Renal Artery Obstruction	8%
165	Renal Artery Stenosis	8%
166	Hemangioma, Cavernous	7.9%
167	Basal Ganglia Cerebrovascular Disease	7.9%
168	Vascular Headaches	7.9%
169	Scurvy	7.9%
170	Human anaplasmosis	7.8%
171	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	7.8%
172	Vertebral Artery Dissection	7.6%
173	Subacute Bacterial Endocarditis	7.5%
174	Pulmonary Embolism	7.4%
175	Subarachnoid Hemorrhage, Traumatic	7.3%
176	Carotid Artery, Internal, Dissection	7.3%
177	Lyme Neuroborreliosis	7.3%
178	Ischemic contracture	7.2%
179	Angioedemas, Hereditary	7.2%
180	Tricuspid Atresia	7.2%
181	Arrhythmogenic Right Ventricular Dysplasia	7.2%
182	Japanese Spotted Fever	7.2%
183	Cryoglobulinemia	7.1%
184	Leukomalacia, Periventricular	7.1%
185	Diabetic Foot	7.1%
186	Thrombosis	7.1%
187	Coronary Occlusion	7%
188	Microvascular Angina	7%
189	Coronary Stenosis	7%
190	ST segment elevation myocardial infarction	7%
191	Carotid Artery Injuries	6.9%
192	Rheumatic Heart Disease	6.7%
193	Central Nervous System Bacterial Infections	6.7%
194	Syphilis	6.5%
195	Erythema Chronicum Migrans	6.5%
196	Shy-Drager Syndrome	6.5%
197	Purpura, Hyperglobulinemic	6.5%
198	Gram-Positive Bacterial Infections	6.4%
199	Cardiac Tamponade	6.3%
200	Endocarditis	6.3%
201	Cardiac Arrest	6.3%
202	Heart failure	6.3%
203	Pericardial effusion	6.3%
204	Pericarditis	6.3%
205	Pneumopericardium	6.3%
206	Cor pulmonale	6.3%
207	Ventricular Outflow Obstruction	6.3%
208	Ventricular Dysfunction	6.3%
209	Cardiomyopathies	6.3%
210	Pleuropericarditis	6.3%
211	Shock, Cardiogenic	6.2%
212	Angina, Unstable	6.2%
213	Rhinoscleroma	6.2%
214	Lupus Vasculitis, Central Nervous System	6%
215	Aortic Valve Stenosis	6%
216	Cardiomyopathy, Dilated	6%
217	Pulmonary Valve Stenosis	6%
218	Arteriosclerosis Obliterans	6%
219	Atherosclerosis	6%
220	Waldenstrom Macroglobulinemia	6%
221	Multiple Myeloma	6%
222	Mouth Abnormalities	6%
223	Ear Neoplasms	5.9%
224	Skin Diseases, Bacterial	5.9%
225	Bacteremia	5.9%
226	Sinus Thrombosis, Intracranial	5.9%
227	Tooth Loss	5.8%
228	Ear Diseases	5.8%
229	Mouth Diseases	5.8%
230	Tooth Diseases	5.8%
231	Chlamydia Infections	5.8%
232	Gonorrhea	5.8%
233	Neurosyphilis	5.7%
234	Basal Ganglia Hemorrhage	5.7%
235	Rheumatoid Vasculitis	5.6%
236	Bacterial Vaginosis	5.6%
237	Ataxia Telangiectasia	5.6%
238	Cardiac Output, High	5.6%
239	Myocardial Stunning	5.6%
240	Low Cardiac Output Syndrome	5.6%
241	Pseudoxanthoma Elasticum	5.6%
242	Cardiomegaly	5.5%
243	Postpericardiotomy Syndrome	5.5%
244	Cardiac Hypertrophy	5.5%
245	Infarction, Middle Cerebral Artery	5.4%
246	Infarction, Anterior Cerebral Artery	5.4%
247	Infarction, Posterior Cerebral Artery	5.4%
248	Cerebral Infarction	5.3%
249	Brain Stem Infarctions	5.3%
250	Heart Block	5.3%
251	Tachycardia	5.3%
252	Tachyarrhythmia	5.3%
253	Aortic coarctation	5.3%
254	Cor Triatriatum	5.3%
255	Coronary Vessel Anomalies	5.3%
256	Patent ductus arteriosus	5.3%
257	Ebstein Anomaly	5.3%
258	Heart Septal Defects	5.3%
259	Tetralogy of Fallot	5.3%
260	Transposition of Great Vessels	5.3%
261	Hypoplastic Left Heart Syndrome	5.3%
262	Intermittent Claudication	5.3%
263	Otomycosis	5.2%
264	No-Reflow Phenomenon	5.2%
265	Jaw Diseases	5.2%
266	Laryngeal Diseases	5.2%
267	Nose Diseases	5.2%
268	Temporomandibular Joint Disorders	5.2%
269	Cerebral Arterial Diseases	5.2%
270	Vertebrobasilar Insufficiency	5.2%
271	Anterior Spinal Artery Syndrome	5.2%
272	Basilar Artery Stenosis	5.2%
273	Vertebral Artery Stenosis	5.2%
274	Intracranial Hemorrhage, Hypertensive	5.2%
275	Transient Cerebral Ischemia	5.2%
276	Facial Hemiatrophy	5.2%
277	Melkersson-Rosenthal Syndrome	5.2%
278	Cleft Palate	5%
279	Pneumonia, Bacterial	5%
280	Rocky Mountain Spotted Fever	5%
281	Labyrinthitis	5%
282	Acinetobacter Infections	4.9%
283	Bacteroides Infections	4.9%
284	Cholera	4.9%
285	Escherichia coli Infections	4.9%
286	Haemophilus Infections	4.9%
287	Klebsiella Infections	4.9%
288	Meningococcal Infections	4.9%
289	Mycoplasma Infections	4.9%
290	Pasteurella Infections	4.9%
291	Proteus Infections	4.9%
292	Rickettsia Infections	4.9%
293	Salmonella infections	4.9%
294	Scrub Typhus	4.9%
295	Serratia Infections	4.9%
296	Ureaplasma Infections	4.9%
297	Laryngeal neoplasm	4.9%
298	Parotid Neoplasms	4.9%
299	Pertussis	4.8%
300	Dextrocardia	4.8%
301	Long QT Syndrome	4.8%
302	Bell Palsy	4.7%
303	Herpes Zoster Oticus	4.6%
304	Hypertension, Renovascular	4.6%
305	Subarachnoid Hemorrhage	4.6%
306	Hypoxia-Ischemia, Brain	4.6%
307	Cerebral Hemorrhage	4.6%
308	Pulmonary Infarction	4.6%
309	Hereditary Angioedema Type III	4.6%
310	Hereditary Angioedema Types I and II	4.6%
311	Radicular Cyst	4.6%
312	Paranasal Sinus Neoplasms	4.6%
313	Coronary Restenosis	4.5%
314	Granulomatosis with polyangiitis	4.5%
315	Cavernous Sinus Thrombosis	4.5%
316	Sagittal Sinus Thrombosis	4.5%
317	Erysipelas	4.4%
318	Staphylococcal Skin Infections	4.4%
319	Dental Enamel Hypoplasia	4.4%
320	Hypodontia	4.4%
321	Macrostomia	4.4%
322	Microstomia	4.4%
323	Salivary Gland Fistula	4.4%
324	Salivary Gland Neoplasms	4.4%
325	Tongue Neoplasms	4.4%
326	Oral candidiasis	4.4%
327	Giant Cell Epulis	4.3%
328	Carcinoid Heart Disease	4.3%
329	Retrognathia	4.3%
330	Venous Thrombosis	4.2%
331	Deep Vein Thrombosis	4.2%
332	Pituitary Apoplexy	4.2%
333	Nose Neoplasms	4.1%
334	Dementia, Vascular	4.1%
335	Mycoses	4.1%
336	Infection	4.1%
337	Primary Ciliary Dyskinesia	4.1%
338	Lemierre Syndrome	4.1%
339	Hypertrophic Cardiomyopathy	4.1%
340	Hypertrophic obstructive cardiomyopathy	4.1%
341	Gingival Recession	4.1%
342	Parotitis	4.1%
343	Gingival Atrophy	4.1%
344	Ecthyma	4%
345	Mycetoma	4%
346	Gingival Hemorrhage	4%
347	Noonan Syndrome	4%
348	Prognathism	4%
349	Angina Pectoris, Variant	4%
350	Erythrasma	3.9%
351	Lateral Medullary Syndrome	3.9%
352	Jaw Abnormalities	3.9%
353	Impetigo	3.8%
354	Putaminal Hemorrhage	3.8%
355	Dysentery, Bacillary	3.8%
356	Bruxism	3.8%
357	Burning Mouth Syndrome	3.8%
358	Dental Leakage	3.8%
359	Hypercementosis	3.8%
360	Lip Diseases	3.8%
361	Malocclusion	3.8%
362	Microglossia	3.8%
363	Oral Submucous Fibrosis	3.8%
364	Otosclerosis	3.8%
365	Periodontal Diseases	3.8%
366	Salivary Gland Diseases	3.8%
367	Stomatitis	3.8%
368	Tongue Diseases	3.8%
369	Tooth Crowding	3.8%
370	Tooth Discoloration	3.8%
371	Tooth Demineralization	3.8%
372	Oral Ulcer	3.8%
373	Tooth Ankylosis	3.8%
374	Tympanosclerosis	3.8%
375	Sick Sinus Syndrome	3.8%
376	Maxillary Sinus Neoplasms	3.7%
377	Meningitis, Haemophilus	3.7%
378	Marfan Syndrome	3.7%
379	Lymphogranuloma Venereum	3.7%
380	Syphilis, Congenital	3.7%
381	Central Nervous System Infection	3.6%
382	Actinomycetales Infections	3.5%
383	Clostridium Infections	3.5%
384	Listeriosis	3.5%
385	Staphylococcal Infections	3.5%
386	Streptococcal Infections	3.5%
387	Bacillaceae Infections	3.5%
388	Clostridium difficile infection	3.5%
389	Supravalvular aortic stenosis	3.5%
390	Lown-Ganong-Levine Syndrome	3.5%
391	Temporomandibular Joint Dysfunction Syndrome	3.4%
392	Hidradenitis Suppurativa	3.4%
393	Aortic Valve Insufficiency	3.4%
394	Restrictive cardiomyopathy	3.4%
395	Endocardial Fibroelastosis	3.4%
396	Heart Rupture, Post-Infarction	3.4%
397	Mitral Valve Insufficiency	3.4%
398	Mitral Valve Stenosis	3.4%
399	Myocarditis	3.4%
400	Pericarditis, Constrictive	3.4%
401	Pulmonary Valve Insufficiency	3.4%
402	Tricuspid Valve Insufficiency	3.4%
403	Tricuspid Valve Stenosis	3.4%
404	Ventricular Dysfunction, Left	3.4%
405	Right Ventricular Dysfunction	3.4%
406	Endomyocardial Fibrosis	3.4%
407	Carditis	3.4%
408	Heart Failure, Systolic	3.4%
409	Heart Failure, Diastolic	3.4%
410	Tympanic Membrane Perforation	3.4%
411	Tooth Injuries	3.4%
412	Ophthalmia Neonatorum	3.4%
413	Trachoma	3.4%
414	Subclavian Steal Syndrome	3.4%
415	Facial Nerve Diseases	3.4%
416	Granuloma, Lethal Midline	3.4%
417	Laryngeal Edema	3.4%
418	Maxillary Diseases	3.4%
419	Nose Deformities, Acquired	3.4%
420	Tooth Resorption	3.4%
421	Granulomatosis, Orofacial	3.4%
422	Congenital Microtia	3.4%
423	Mouth Neoplasms	3.3%
424	Oral Fistula	3.3%
425	Toothache	3.3%
426	Lichen Planus, Oral	3.3%
427	Palatal Neoplasms	3.3%
428	Psittacosis	3.3%
429	Paratyphoid Fever	3.3%
430	Plague	3.3%
431	Typhoid Fever	3.3%
432	TYPHUS	3.3%
433	Yersinia pseudotuberculosis Infections	3.3%
434	Bubonic Plague	3.3%
435	Erysipelothrix infection	3.2%
436	Adams-Stokes Syndrome	3.1%
437	Atrioventricular Block	3.1%
438	Bundle-Branch Block	3.1%
439	Atrial Premature Complexes	3.1%
440	Sinoatrial Block	3.1%
441	Tachycardia, Paroxysmal	3.1%
442	Supraventricular tachycardia	3.1%
443	Tachycardia, Ventricular	3.1%
444	Wolff-Parkinson-White Syndrome	3.1%
445	Tachycardia, Reciprocating	3.1%
446	Aortopulmonary Septal Defect	3.1%
447	Double Outlet Right Ventricle	3.1%
448	Endocardial Cushion Defects	3.1%
449	Myocardial bridging	3.1%
450	Aorticopulmonary Septal Defect	3.1%
451	Kartagener Syndrome	3%
452	Laryngitis	3%
453	Rhinitis	3%
454	Vocal Cord Dysfunction	3%
455	Sinus Arrhythmia	3%
456	Atrial Fibrillation	3%
457	Atrial Flutter	3%
458	Edema, Cardiac	3%
459	Ventricular Fibrillation	3%
460	Ventricular Flutter	3%
461	Parasystole	3%
462	Paroxysmal atrial fibrillation	3%
463	Bradycardia	3%
464	Diabetic Cardiomyopathies	3%
465	Micrognathism	3%
466	Pierre Robin Syndrome	3%
467	Hordeolum	3%
468	Cerebral Amyloid Angiopathy	3%
469	Laryngostenosis	3%
470	Nasal Polyps	3%
471	Cardiomyopathy, Alcoholic	3%
472	Ectopia Cordis	3%
473	Sudden Cardiac Death	3%
474	Left Ventricular Hypertrophy	3%
475	Right Ventricular Hypertrophy	3%
476	Single umbilical artery	3%
477	Chagas Cardiomyopathy	3%
478	Bacterial conjunctivitis	3%
479	Facial paralysis	2.9%
480	Facial Paresis	2.9%
481	Dysacusis	2.9%
482	Salmonella Infections, Animal	2.9%
483	Meningitis, Listeria	2.9%
484	Hemifacial Spasm	2.9%
485	Salmonella food poisoning	2.9%
486	Acoustic Neuroma	2.8%
487	Cheilitis	2.8%
488	Cochlear Diseases	2.8%
489	Dental caries	2.8%
490	Dental Plaque	2.8%
491	Dental Pulp Calcification	2.8%
492	Drooling	2.8%
493	Gingival Diseases	2.8%
494	Glossitis	2.8%
495	Macroglossia	2.8%
496	Otitis Externa	2.8%
497	Otitis Media	2.8%
498	Periodontitis	2.8%
499	Pulpitis	2.8%
500	Sialadenitis	2.8%
501	Sialometaplasia, Necrotizing	2.8%
502	Sialorrhea	2.8%
503	Aphthous Stomatitis	2.8%
504	Tooth Erosion	2.8%
505	Vestibular Diseases	2.8%
506	Xerostomia	2.8%
507	Endolymphatic Hydrops	2.8%
508	Glossoptosis	2.8%
509	Peri-Implantitis	2.8%
510	Romano-Ward Syndrome	2.8%
511	Staphylococcal Scalded Skin Syndrome	2.8%
512	MELAS Syndrome	2.8%
513	Meningitis, Bacterial	2.7%
514	Choanal Atresia	2.7%
515	Voice Disorders	2.7%
516	Voice Disturbance	2.7%
517	Laryngocele	2.7%
518	Epistaxis	2.7%
519	Maxillofacial Abnormalities	2.7%
520	Dyspnea, Paroxysmal	2.7%
521	Dermatomycoses	2.6%
522	Furunculosis	2.5%
523	furuncle	2.5%
524	Vestibulocochlear Nerve Diseases	2.5%
525	Tooth Avulsion	2.5%
526	Croup	2.5%
527	Dental Pulp Necrosis	2.5%
528	Facial Neuralgia	2.5%
529	Rhinitis, Vasomotor	2.5%
530	Turner Syndrome	2.5%
531	Dental Fistula	2.5%
532	Oroantral Fistula	2.5%
533	Laryngomalacia	2.5%
534	Granuloma, Laryngeal	2.4%
535	Meningitis, Pneumococcal	2.4%
536	Vocal Cord Paralysis	2.4%
537	Dural Arteriovenous Fistula	2.4%
538	Mastoiditis	2.4%
539	Petrositis	2.4%
540	Gingivitis	2.3%
541	Glossitis, Benign Migratory	2.3%
542	Meniere Disease	2.3%
543	Otitis Media with Effusion	2.3%
544	Pericoronitis	2.3%
545	Aggressive Periodontitis	2.3%
546	Gingival Overgrowth	2.3%
547	Fabry Disease	2.3%
548	Vesicular Stomatitis	2.2%
549	Hematoma, Subdural	2.2%
550	Hematoma, Epidural, Cranial	2.2%
551	Sinusitis	2.2%
552	Laryngospasm	2.2%
553	Sleep Bruxism	2.2%
554	Hyperacusis	2.2%
555	Tinnitus	2.2%
556	Phonophobia	2.2%
557	Hearing Loss	2.2%
558	Aspergillosis	2.1%
559	Candidiasis	2.1%
560	Coccidioidomycosis	2.1%
561	Histoplasmosis	2.1%
562	Paracoccidioidomycosis	2.1%
563	Pelvic Infection	2.1%
564	Wound Infection	2.1%
565	Zygomycosis	2.1%
566	Soft Tissue Infection	2.1%
567	Community-Acquired Infections	2.1%
568	Phaeohyphomycosis	2.1%
569	Pneumocystis Infections	2.1%
570	Candidiasis, Chronic Mucocutaneous	2.1%
571	Cutaneous Candidiasis	2.1%
572	Actinomycosis	2.1%
573	Corynebacterium Infections	2.1%
574	Gas Gangrene	2.1%
575	Mycobacterium Infections	2.1%
576	Nocardia Infections	2.1%
577	Pneumococcal Infections	2.1%
578	Scarlet Fever	2.1%
579	Tetanus	2.1%
580	Pulmonary Nocardiosis	2.1%
581	Gingival Hyperplasia	2.1%
582	Gingival Hypertrophy	2.1%
583	Brain Hemorrhage, Traumatic	2.1%
584	Alveolar Bone Loss	2.1%
585	Vestibular Neuronitis	2.1%
586	Trigeminal Nerve Disorder	2%
587	Panophthalmitis	2%
588	Mobius Syndrome	2%
589	Aortic Valve Prolapse	2%
590	Tricuspid Valve Prolapse	2%
591	Takotsubo Cardiomyopathy	2%
592	Brain Abscess	2%
593	Tachycardia, Atrioventricular Nodal Reentry	2%
594	Tachycardia, Ectopic Atrial	2%
595	Tachycardia, Ectopic Junctional	2%
596	Sinus Tachycardia	2%
597	Torsades de Pointes	2%
598	Accelerated Idioventricular Rhythm	2%
599	Truncus Arteriosus, Persistent	2%
600	Aphonia	2%
601	Leukoplakia, Oral	2%
602	Dysphonia	2%
603	Herpes Labialis	2%
604	carbuncle	1.9%
605	Eye Infection	1.9%
606	Respiratory Tract Infections	1.9%
607	Bone Diseases, Infectious	1.9%
608	Pregnancy Complications, Infectious	1.9%
609	Skin Diseases, Infectious	1.9%
610	Tuberculosis, Meningeal	1.9%
611	Arthritis, Infectious	1.9%
612	Piedra	1.9%
613	Central Nervous System Fungal Infections	1.9%
614	Suppuration	1.9%
615	Cross Infection	1.9%
616	Septicemia	1.9%
617	Sepsis	1.9%
618	Erythema Induratum	1.9%
619	Vertigo	1.8%
620	Mumps	1.8%
621	Trigeminal Neuralgia	1.8%
622	Neuroaspergillosis	1.8%
623	Fungemia	1.8%
624	Deafness	1.8%
625	Hearing Loss, Sudden	1.8%
626	Hearing Loss, Bilateral	1.8%
627	Hearing Loss, High-Frequency	1.8%
628	Hearing Loss, Mixed Conductive-Sensorineural	1.8%
629	Hearing Loss, Unilateral	1.8%
630	Complete Hearing Loss	1.8%
631	Deaf Mutism	1.8%
632	Facial Nerve Injuries	1.8%
633	Waterhouse-Friderichsen Syndrome	1.8%
634	Blastomycosis	1.8%
635	Candidemia	1.8%
636	Opportunistic Infections	1.7%
637	Sinus Arrest, Cardiac	1.7%
638	Joint Tuberculosis	1.7%
639	Tuberculosis, Osteoarticular	1.7%
640	Bone Tuberculosis	1.7%
641	Lung Diseases, Fungal	1.7%
642	Urinary tract infection	1.7%
643	Hoarseness	1.7%
644	Cellulitis	1.7%
645	Rheumatic Fever	1.7%
646	Hay fever	1.6%
647	Rhinitis, Allergic, Perennial	1.6%
648	Enterocolitis, Pseudomembranous	1.6%
649	pseudomembranous colitis	1.6%
650	Toxic Epidermal Necrolysis	1.6%
651	Stevens-Johnson Syndrome	1.6%
652	Hematoma, Subdural, Intracranial	1.6%
653	Hematoma, Subdural, Chronic	1.6%
654	Hematoma, Subdural, Acute	1.6%
655	Sexually Transmitted Diseases	1.5%
656	Botulism	1.5%
657	Kearns-Sayre syndrome	1.5%
658	Chromoblastomycosis	1.5%
659	Dermatophytosis	1.5%
660	Sporotrichosis	1.5%
661	Tinea	1.5%
662	Tinea Versicolor	1.5%
663	Trichophytosis	1.5%
664	Invasive Pulmonary Aspergillosis	1.5%
665	Hyalohyphomycosis	1.5%
666	Endotoxemia	1.5%
667	Diphtheria	1.4%
668	Leprosy	1.4%
669	Mycobacterium Infections, Nontuberculous	1.4%
670	Tuberculosis	1.4%
671	Mycobacterium abscessus Infection	1.4%
672	Sicca Syndrome	1.4%
673	Sjogren's Syndrome	1.4%
674	Auditory Perceptual Disorders	1.4%
675	Meningitis, Cryptococcal	1.3%
676	Mucormycosis	1.2%
677	Tuberculosis, Spinal	1.1%
678	Basal Cell Nevus Syndrome	1.1%
679	Mycobacterium avium-intracellulare Infection	1.1%
680	Lymph Node Tuberculosis	1.1%
681	Tuberculosis, Miliary	1.1%
682	Tuberculosis, Multidrug-Resistant	1.1%
683	Leprosy, Multibacillary	1.1%
684	Latent Tuberculosis	1.1%
685	Endophthalmitis	1%
686	Peritonitis	1%
687	Osteomyelitis	1%
688	Periostitis	1%
689	Surgical Wound Infection	1%
690	Pulmonary Aspergillosis	1%
691	Bronchopulmonary Aspergillosis	1%
692	Abscess	1%
693	Adnexitis	1%
694	Empyema	1%
695	Pelvic Inflammatory Disease	1%
696	Superinfection	0.9%
697	Tuberculosis, Gastrointestinal	0.9%
698	Corneal Ulcer	0.9%
699	Tuberculosis, Central Nervous System	0.9%
700	Puerperal Infection	0.9%
701	Spondylitis	0.9%
702	Appendicitis	0.9%
703	Bacteriuria	0.9%
704	Pyuria	0.9%
705	Meningitis, Fungal	0.9%
706	Pyomyositis	0.9%
707	Endotoxic shock	0.9%
708	Septic Shock	0.9%
709	Toxic Shock Syndrome	0.9%
710	Candidiasis, Vulvovaginal	0.9%
711	Fusariosis	0.9%
712	Williams Syndrome	0.9%
713	Toxoplasmosis, Cerebral	0.9%
714	Borderline leprosy	0.9%
715	Leprosy, Lepromatous	0.9%
716	Tuberculoid leprosy	0.9%
717	Extensively Drug-Resistant Tuberculosis	0.9%
718	Tuberculosis, Pulmonary	0.8%
719	Tinea Capitis	0.8%
720	Onychomycosis	0.8%
721	Arthritis, Reactive	0.8%
722	AIDS-Related Opportunistic Infections	0.8%
723	Tinea Pedis	0.7%
724	Psoas Abscess	0.7%
725	Abdominal Abscess	0.7%
726	Diverticulitis	0.6%
727	Tuberculosis, Renal	0.6%
728	Lung Abscess	0.6%
729	Diverticulum	0.6%
730	Diverticulosis	0.6%
731	Discitis	0.5%
732	Epidural Abscess	0.5%
733	Aspergillosis, Allergic Bronchopulmonary	0.5%
734	Liver Abscess	0.4%
735	Liver Abscess, Amebic	0.2%

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