MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Sick Building Syndrome

(UMLS:C0037050)

Definition:: A group of symptoms that are two- to three-fold more common in those who work in large, energy-efficient buildings, associated with an increased frequency of headaches, lethargy, and dry skin. Clinical manifestations include hypersensitivity pneumonitis (ALVEOLITIS, EXTRINSIC ALLERGIC); allergic rhinitis (RHINITIS, ALLERGIC, PERENNIAL); ASTHMA; infections, skin eruptions, and mucous membrane irritation syndromes. Current usage tends to be less restrictive with regard to the type of building and delineation of complaints. (From Segen, Dictionary of Modern Medicine, 1992)
UMLS ID:: C0037050
MeSH ID:: D018877

Classification 1:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.312.750

Classification 2:

Name:

Disorders of Environmental Origin
MeSH Tree Number(s):: C21.223.750

Synonym(s)

Sick Building Syndrome

Sick building syndrome

building sick syndromes

sick building syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Terbinafine	FAERS: 1		US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Multiple Chemical Sensitivity	44.8%
2	Immune Complex Diseases	20.9%
3	Latex allergy	20.9%
4	anaphylaxis	13.6%
5	Food Allergy	13.6%
6	Anaphylactic shock	13.6%
7	Kounis Syndrome	12.3%
8	Autoimmune Diseases	12.2%
9	Immunologic Deficiency Syndromes	12.2%
10	Immunoproliferative Disorders	12.2%
11	Immune reconstitution syndrome	12.2%
12	Immune Reconstitution Inflammatory Syndrome	12.2%
13	Serum Sickness	11.6%
14	Asthma, Aspirin-Induced	11.5%
15	Respiratory Hypersensitivity	10.7%
16	Urticaria	10.2%
17	Vasculitis, Leukocytoclastic, Cutaneous	10.2%
18	Milk Allergy	10.1%
19	Wheat Hypersensitivity	10.1%
20	Transfusion Reaction	9.1%
21	Hypotensive Transfusion Reaction	9.1%
22	Mastocytosis	8.2%
23	Drug Eruptions	8.1%
24	Dermatitis, Allergic Contact	8%
25	Mastocytosis, Systemic	7.5%
26	Antiphospholipid Syndrome	7%
27	Glomerulonephritis, Membranoproliferative	6.9%
28	Angioedema	6.1%
29	Acute Generalized Exanthematous Pustulosis	6%
30	Dermatitis, Atopic	5.8%
31	Autoimmune Lymphoproliferative Syndrome	5.7%
32	Lupus Erythematosus, Systemic	5.3%
33	Lymphoproliferative Disorders	5.3%
34	Overlap syndrome	5.3%
35	Addison Disease	5.2%
36	Paraproteinemias	5.2%
37	Pemphigus	5.2%
38	Autoimmune thyroiditis	5.2%
39	Primary Adrenal Insufficiency	5.2%
40	Asthma	5.1%
41	Lymphopenia	5.1%
42	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5.1%
43	Autoimmune hepatitis	5.1%
44	Asthma, Exercise-Induced	5%
45	Status Asthmaticus	5%
46	Erythema Nodosum	5%
47	Dermatitis, Photoallergic	4.9%
48	Thrombocytopenic purpura	4.8%
49	Primary amyloidosis	4.5%
50	Monoclonal Gammopathy of Undetermined Significance	4.4%
51	Autoimmune thrombocytopenia	4.4%
52	Immune thrombocytopenic purpura	4.4%
53	Hereditary Angioedema Type III	4.4%
54	Hereditary Angioedema Types I and II	4.4%
55	Asthma, Occupational	4.3%
56	Aspergillosis, Allergic Bronchopulmonary	4.3%
57	Farmer's Lung	4.2%
58	Angioedemas, Hereditary	4.2%
59	Hypergammaglobulinemia	4.2%
60	Latent Autoimmune Diabetes in Adults	4.1%
61	Hay fever	4.1%
62	Rhinitis, Allergic, Perennial	4.1%
63	Agammaglobulinemia	4.1%
64	Dermatitis Herpetiformis	4.1%
65	HIV Infections	4.1%
66	Transfusion-Related Acute Lung Injury	4.1%
67	Toxic Epidermal Necrolysis	3.7%
68	Stevens-Johnson Syndrome	3.7%
69	Rheumatoid Arthritis	3.4%
70	Juvenile arthritis	3.4%
71	Graves Disease	3.4%
72	Plasmacytoma	3.4%
73	Tumor Lysis Syndrome	3.4%
74	Schnitzler Syndrome	3.4%
75	HTLV-I Infections	3.4%
76	Job Syndrome	3.4%
77	Anti-Glomerular Basement Membrane Disease	3.3%
78	Multiple Myeloma	3.3%
79	Sezary Syndrome	2.9%
80	Lymphoma	2.7%
81	Myasthenia Gravis	2.7%
82	Uveomeningoencephalitic Syndrome	2.7%
83	Chronic granulomatous disease	2.7%
84	Heavy Chain Disease	2.7%
85	Granulomatosis with polyangiitis	2.7%
86	HIV Seropositivity	2.7%
87	Kernicterus	2.5%
88	Myasthenia Gravis, Autoimmune, Experimental	2.5%
89	Stiff-Person Syndrome	2.3%
90	Polyradiculoneuropathy	2.3%
91	Polyradiculoneuritis	2.3%
92	Ataxia Telangiectasia	2.3%
93	Acquired Immunodeficiency Syndrome	2.2%
94	AIDS related complex	2.2%
95	Infectious Mononucleosis	2.2%
96	Cryoglobulinemia	2.2%
97	Felty Syndrome	2.2%
98	Hydrops Fetalis	2.2%
99	POEMS Syndrome	2.2%
100	Lupus Nephritis	2.2%
101	Multiple Sclerosis	2%
102	Hodgkin Disease	2%
103	Leukemia, Plasma Cell	2%
104	Lymphoma, Non-Hodgkin	2%
105	Leukemia, T-Cell	2%
106	Leukemia, B-Cell	2%
107	AIDS-Related Opportunistic Infections	1.9%
108	Vasculitis, Central Nervous System	1.9%
109	HIV Wasting Syndrome	1.9%
110	Rheumatoid Vasculitis	1.9%
111	AIDS Dementia Complex	1.9%
112	AIDS-Associated Nephropathy	1.9%
113	Neuromyelitis Optica	1.8%
114	Leukoencephalitis, Acute Hemorrhagic	1.8%
115	Lupus Vasculitis, Central Nervous System	1.8%
116	Lambert-Eaton Myasthenic Syndrome	1.7%
117	Waldenstrom Macroglobulinemia	1.7%
118	Composite Lymphoma	1.7%
119	Wiskott-Aldrich Syndrome	1.7%
120	Encephalomyelitis, Acute Disseminated	1.7%
121	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	1.7%
122	Sicca Syndrome	1.7%
123	Sjogren's Syndrome	1.7%
124	Neuritis, Autoimmune, Experimental	1.7%
125	Multiple Sclerosis, Chronic Progressive	1.7%
126	Multiple Sclerosis, Relapsing-Remitting	1.7%
127	Lymphangioleiomyomatosis	1.6%
128	Lymphoma, Follicular	1.6%
129	T-Cell Lymphoma	1.6%
130	Mantle cell lymphoma	1.6%
131	HIV-Associated Lipodystrophy Syndrome	1.6%
132	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1.6%
133	Leukemia, Large Granular Lymphocytic	1.6%
134	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1.6%
135	Lymphoma, T-Cell, Cutaneous	1.5%
136	Lymphoma, AIDS-Related	1.5%
137	Enteropathy-Associated T-Cell Lymphoma	1.5%
138	Primary Effusion Lymphoma	1.5%
139	Guillain-Barre Syndrome	1.4%
140	Mycosis Fungoides	1.4%
141	Lymphomatoid Papulosis	1.4%
142	Plasmablastic lymphoma	1.4%
143	Lymphomatoid Granulomatosis	1.2%
144	Giant Cell Arteritis	1.1%
145	Temporal Arteritis	1.1%
146	Burkitt Lymphoma	1.1%
147	Myelitis, Transverse	1%
148	Miller Fisher Syndrome	0.8%

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