MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

AIDS-Associated Nephropathy

(UMLS:C0078911)

Definition:: Renal syndrome in human immunodeficiency virus-infected patients characterized by nephrotic syndrome, severe proteinuria, focal and segmental glomerulosclerosis with distinctive tubular and interstitial changes, enlarged kidneys, and peculiar tubuloreticular structures. The syndrome is distinct from heroin-associated nephropathy as well as other forms of kidney disease seen in HIV-infected patients.
UMLS ID:: C0078911
MeSH ID:: D016263

Classification 1:

Name:

Virus Diseases
MeSH Tree Number(s):: C02.782.815.616.400.050|C02.800.801.400.072

Classification 2:

Name:

Male Urogenital Diseases
MeSH Tree Number(s):: C12.777.419.050

Classification 3:

Name:

Female Urogenital Diseases and Pregnancy Complications
MeSH Tree Number(s):: C13.351.968.419.050

Classification 4:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.673.480.050

Synonym(s)

AIDS-Associated Nephropathy

AIDS - Acquired immune deficiency synd-related nephropathy

AIDS NEPHROPATHY

AIDS-Related Nephropathy

Acquired immune deficiency syndrome-related nephropathy

HIV NEPHROPATHY

HIV Nephropathy

HIV associated nephropathy

HIV nephropathy

10.

HIV-Associated Nephropathy

11.

HIV-associated Nephropathy

12.

HIV-associated nephropathy

13.

HIVAN

14.

Human immunodeficiency virus-related nephropathy

15.

hiv-associated nephropathy

16.

nephropathy HIV

17.

nephropathy aids-associated

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Indinavir		11110045 19226409	CTD
2	Tenofovir		19226409 19274046	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	HIV Seropositivity	37.4%
2	Acquired Immunodeficiency Syndrome	37%
3	AIDS related complex	37%
4	Anuria	30.5%
5	Nephrolithiasis	30.5%
6	HIV Wasting Syndrome	30.1%
7	AIDS Dementia Complex	30%
8	HIV-Associated Lipodystrophy Syndrome	27.1%
9	Hydronephrosis	27%
10	Hyperoxaluria	27%
11	Kidney Cortex Necrosis	27%
12	Kidney Papillary Necrosis	27%
13	Nephritis	27%
14	Nephrosclerosis	27%
15	Nephrosis	27%
16	Perinephritis	27%
17	Kidney Failure	27%
18	Uremia	27%
19	Oxalosis	27%
20	Renal Insufficiency	27%
21	Pyelonephritis	25.9%
22	Tuberculosis, Renal	24%
23	Diabetes Insipidus	23.9%
24	Hepatorenal Syndrome	23.9%
25	Diabetic Nephropathy	23.7%
26	Renal hypertension	23.7%
27	Renal Artery Obstruction	23.7%
28	Renal Artery Stenosis	23.7%
29	Nephrocalcinosis	23.6%
30	AIDS-Related Opportunistic Infections	23.3%
31	Kidney Neoplasm	22.2%
32	Kidney Calculi	22.2%
33	Glomerulonephritis	20.1%
34	Nephritis, Interstitial	20.1%
35	Lipoid nephrosis	20.1%
36	Nephrotic Syndrome	20.1%
37	Pyelitis	20.1%
38	Pyonephrosis	20.1%
39	Nephrogenic Diabetes Insipidus	20.1%
40	Congenital Nephrogenic Diabetes Insipidus	20.1%
41	Acute kidney injury	20.1%
42	Pyelocystitis	20%
43	Multicystic Dysplastic Kidney	19.2%
44	Glomerulonephritis, Membranoproliferative	19.2%
45	Ureterolithiasis	18.9%
46	Urinary Bladder Diseases	18.4%
47	Ureteral Diseases	18.4%
48	Urethral Diseases	18.4%
49	Urination Disorders	18.4%
50	Urolithiasis	18.4%
51	Azotemia	17.8%
52	Hypertension, Renovascular	17.6%
53	Glycosuria, Renal	17%
54	Balkan Nephropathy	16.7%
55	Focal glomerulosclerosis	16.7%
56	Kidney Failure, Chronic	16.7%
57	Bladder neck obstruction	16.4%
58	Urinary tract infection	16.3%
59	Polycystic Kidney Diseases	15.8%
60	Ureteral Calculi	15.7%
61	Renal Osteodystrophy	15.7%
62	Renal rickets	15.7%
63	Renal Aminoacidurias	15.6%
64	Fanconi Syndrome	15.6%
65	Pseudohypoaldosteronism	15.6%
66	Liddle Syndrome	15.6%
67	Hemolytic-Uremic Syndrome	15.6%
68	Genital Herpes	15.4%
69	Anti-Glomerular Basement Membrane Disease	15.4%
70	Mesoblastic Nephroma	15%
71	Renal Cell Carcinoma	14.9%
72	Papillary Renal Cell Carcinoma	14.9%
73	Lupus Nephritis	14.5%
74	Renal tubular acidosis	14.1%
75	Simian Acquired Immunodeficiency Syndrome	14%
76	Bladder Exstrophy	13.6%
77	Epispadias	13.6%
78	Polycystic Kidney, Autosomal Dominant	13%
79	Cystinuria	13%
80	Atypical Hemolytic Uremic Syndrome	12.9%
81	Nephroblastoma	12.8%
82	Zellweger Syndrome	12.6%
83	Murine Acquired Immunodeficiency Syndrome	12.5%
84	Condylomata Acuminata	12.4%
85	Cystitis	12.1%
86	Ureteral obstruction	12.1%
87	Ureterocele	12.1%
88	Urethral Obstruction	12.1%
89	Urethritis	12.1%
90	Vesico-Ureteral Reflux	12.1%
91	Urinary Retention	12.1%
92	Rift Valley Fever	12.1%
93	Urinary Bladder Fistula	11.7%
94	Bladder Neoplasm	11.7%
95	Ureteral Neoplasms	11.7%
96	Urethral Neoplasms	11.7%
97	Hyperphosphaturia	11.7%
98	Hepatitis E	11.6%
99	HTLV-I Infections	11.4%
100	Dengue Fever	10.9%
101	Yellow Fever	10.9%
102	Hemorrhagic Fever, Crimean	10.9%
103	Urogenital Abnormalities	10.7%
104	Bacteriuria	10.6%
105	Glycosuria	10.6%
106	Hematuria	10.6%
107	Oliguria	10.6%
108	Polyuria	10.6%
109	Proteinuria	10.6%
110	Pyuria	10.6%
111	Urinary Calculi	10.6%
112	Cystocele	10.6%
113	Urinary Incontinence	10.6%
114	Orthomyxoviridae Infections	10.2%
115	Picornaviridae Infections	10.2%
116	Reoviridae Infections	10.2%
117	Arbovirus Infections	9.9%
118	Hemorrhagic Fever, American	9.8%
119	Lassa Fever	9.8%
120	Enuresis	9.5%
121	Phlebotomus Fever	9.5%
122	Denys-Drash Syndrome	9.5%
123	Warts	9.1%
124	Urethral Stenosis	9%
125	Urethral stricture	9%
126	Sexually Transmitted Diseases	8.9%
127	Lymphopenia	8.5%
128	Hepatitis, Viral, Human	8.4%
129	Viremia	8.4%
130	Hepatitis C	8.2%
131	Hemorrhagic Fever with Renal Syndrome	7.9%
132	Albuminuria	7.9%
133	Hemoglobinuria	7.9%
134	Urge Incontinence	7.9%
135	West Nile Fever	7.9%
136	Subacute Sclerosing Panencephalitis	7.7%
137	Opportunistic Infections	7.6%
138	Zika Virus Infection	7.5%
139	Agammaglobulinemia	7.5%
140	Hepatitis, Viral, Animal	7.4%
141	Pneumonia, Viral	7.4%
142	Infertility	7.1%
143	Epstein-Barr Virus Infections	7.1%
144	Leukoencephalopathy, Progressive Multifocal	7.1%
145	Diurnal Enuresis	7%
146	Hypospadias	7%
147	Familial Hypophosphatemic Rickets	6.8%
148	Chronic Fatigue Syndrome	6.6%
149	Hepatitis A	6.6%
150	Vesicovaginal Fistula	6.3%
151	Urologic Neoplasms	6.2%
152	Horseshoe Kidney	6.2%
153	Hepatitis B	6.2%
154	Molluscum Contagiosum	6.2%
155	Enterovirus Infections	5.7%
156	Flavivirus Infections	5.7%
157	Paramyxoviridae Infections	5.7%
158	Cardiovirus Infections	5.7%
159	Rhabdoviridae Infections	5.7%
160	Autoimmune Diseases	5.6%
161	Genital Diseases, Male	5.6%
162	Hypersensitivity	5.6%
163	Immunoproliferative Disorders	5.6%
164	Immune reconstitution syndrome	5.6%
165	Immune Reconstitution Inflammatory Syndrome	5.6%
166	Pseudorabies	5.6%
167	Job Syndrome	5.6%
168	Hermaphroditism	5.6%
169	Disorders of Sex Development	5.6%
170	Erythema Infectiosum	5.5%
171	Epidermodysplasia Verruciformis	5.3%
172	Herpesviridae Infections	5.2%
173	Polyomavirus Infections	5.2%
174	Pregnancy Complications	5.1%
175	Foot-and-Mouth Disease	5.1%
176	Genital Neoplasms, Male	5%
177	Ataxia Telangiectasia	5%
178	Common Cold	5%
179	Influenza	5%
180	Catarrh	5%
181	Herpes Zoster Ophthalmicus	4.9%
182	Chronic granulomatous disease	4.9%
183	Endometriosis	4.9%
184	Uterine Diseases	4.9%
185	Vaginal Diseases	4.9%
186	Vulvar Diseases	4.9%
187	Endometrioma	4.9%
188	Uterine Neoplasms	4.9%
189	Vaginal Neoplasms	4.9%
190	Vulvar Neoplasms	4.9%
191	Uterine Cancer	4.9%
192	Transfusion Reaction	4.9%
193	Hypotensive Transfusion Reaction	4.9%
194	Endometritis	4.9%
195	Keratitis, Herpetic	4.8%
196	Cytomegalovirus Retinitis	4.8%
197	Exanthema Subitum	4.8%
198	Penile Neoplasms	4.4%
199	Prostatic Neoplasms	4.4%
200	Hepatitis C, Chronic	4.3%
201	Fallopian Tube Neoplasms	4.3%
202	Genital Neoplasms, Female	4.2%
203	Uterine Inversion	4.2%
204	Herpangina	4.2%
205	Salpingitis	4.2%
206	Vulvovaginitis	4.2%
207	Dyspareunia	4.1%
208	Superinfection	4%
209	Hyperandrogenism	3.7%
210	Uterine Rupture	3.7%
211	Autoimmune Lymphoproliferative Syndrome	3.7%
212	Cryptorchidism	3.7%
213	Eczema Herpeticum	3.7%
214	Oophoritis	3.7%
215	Burkitt Lymphoma	3.6%
216	Gonadal Dysgenesis	3.6%
217	Adrenogenital Syndrome	3.6%
218	Ovotesticular Disorders of Sex Development	3.6%
219	Endometrial Neoplasms	3.6%
220	Wiskott-Aldrich Syndrome	3.6%
221	Coxsackievirus Infections	3.5%
222	Rubella	3.5%
223	Coronavirus Infections	3.5%
224	Nipah Virus Infection	3.5%
225	Hydrophobia	3.5%
226	Carcinoma, Endometrioid	3.5%
227	ovarian neoplasm	3.5%
228	Thrombocytopenic purpura	3.3%
229	Epididymitis	3.3%
230	Immune Complex Diseases	3.3%
231	Penile Diseases	3.3%
232	Prostatic Diseases	3.3%
233	Spermatic Cord Torsion	3.3%
234	Antiphospholipid Syndrome	3.3%
235	Hemospermia	3.3%
236	Latex allergy	3.3%
237	Testicular Hydrocele	3.3%
238	Autoimmune thrombocytopenia	3.3%
239	Immune thrombocytopenic purpura	3.3%
240	Herpes Labialis	3.3%
241	Endometrial Hyperplasia	3.3%
242	Pyometra	3.3%
243	Vaginitis	3.3%
244	Vulvitis	3.3%
245	Vaginal Discharge	3.3%
246	Vulvodynia	3.3%
247	Hepatitis B, Chronic	3.2%
248	Prostatic Neoplasms, Castration-Resistant	3.2%
249	Porcine Reproductive and Respiratory Syndrome	3.1%
250	Candidiasis, Vulvovaginal	3%
251	Uterine Cervical Incompetence	3%
252	Cytomegalovirus Infections	3%
253	Smallpox	3%
254	Varicella Zoster Virus Infection	3%
255	Chorioamnionitis	2.9%
256	Environmental Illness	2.9%
257	Primary amyloidosis	2.9%
258	Monoclonal Gammopathy of Undetermined Significance	2.9%
259	Lupus Erythematosus, Systemic	2.9%
260	Lymphoproliferative Disorders	2.9%
261	Testicular Diseases	2.9%
262	Varicocele	2.9%
263	Overlap syndrome	2.9%
264	Addison Disease	2.8%
265	Paraproteinemias	2.8%
266	Pemphigus	2.8%
267	Spermatocele	2.8%
268	Autoimmune thyroiditis	2.8%
269	Primary Adrenal Insufficiency	2.8%
270	Ovarian Diseases	2.8%
271	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	2.8%
272	Autoimmune hepatitis	2.8%
273	Abruptio Placentae	2.8%
274	Placenta Accreta	2.8%
275	Adnexitis	2.8%
276	Pruritus Vulvae	2.8%
277	Uterine hemorrhage	2.8%
278	Vaginal Fistula	2.8%
279	Pelvic Inflammatory Disease	2.8%
280	Uterine Prolapse	2.8%
281	Vaginal Prolapse	2.8%
282	Polyhydramnios	2.8%
283	Obstetric Labor Complications	2.8%
284	Ectopic Pregnancy	2.8%
285	Pregnancy, Prolonged	2.8%
286	Puerperal Disorders	2.8%
287	Retroviridae Infections	2.8%
288	Oligohydramnios	2.8%
289	Prenatal Injuries	2.8%
290	Infectious Mononucleosis	2.7%
291	Vesicular Stomatitis	2.7%
292	Turner Syndrome	2.7%
293	Asthma, Aspirin-Induced	2.6%
294	Serum Sickness	2.5%
295	Hypergammaglobulinemia	2.5%
296	Latent Autoimmune Diabetes in Adults	2.5%
297	Dermatitis Herpetiformis	2.5%
298	Kounis Syndrome	2.5%
299	Transfusion-Related Acute Lung Injury	2.5%
300	Puerperal Infection	2.5%
301	Postpartum Hemorrhage	2.5%
302	Chlamydia Infections	2.4%
303	Gonorrhea	2.4%
304	Fetal Diseases	2.4%
305	Pregnancy Complications, Cardiovascular	2.4%
306	Pregnancy Complications, Neoplastic	2.4%
307	Uterine Cervicitis	2.4%
308	Leukorrhea	2.4%
309	Measles	2.4%
310	Parametritis	2.4%
311	Pleurodynia, Epidemic	2.4%
312	Respiratory Syncytial Virus Infections	2.4%
313	granulosa cell tumor	2.4%
314	Carcinoma, Ovarian Epithelial	2.4%
315	Endometrial Stromal Sarcoma	2.4%
316	Testicular Neoplasms	2.4%
317	Pregnancy Complications, Hematologic	2.4%
318	Pregnancy Complications, Infectious	2.4%
319	Multiple Myeloma	2.4%
320	Poliomyelitis	2.4%
321	Fetal Death	2.4%
322	Perinatal death	2.4%
323	Morning Sickness	2.4%
324	Kallmann Syndrome	2.2%
325	Rheumatoid Arthritis	2.2%
326	Juvenile arthritis	2.2%
327	Syphilis	2.2%
328	Graves Disease	2.2%
329	Hydrops Fetalis	2.2%
330	anaphylaxis	2.2%
331	Balanitis	2.2%
332	Benign prostatic hypertrophy	2.2%
333	Food Allergy	2.2%
334	Phimosis	2.2%
335	Priapism	2.2%
336	prostatitis	2.2%
337	Prostatic Adenoma	2.2%
338	Benign Prostatic Hyperplasia	2.2%
339	Prostatic Hypertrophy	2.2%
340	Prostatic Hyperplasia	2.2%
341	Anaphylactic shock	2.2%
342	Gastroenteritis, Transmissible, of Swine	2.1%
343	Bacterial Vaginosis	2.1%
344	Severe Acute Respiratory Syndrome	2.1%
345	Trichomonas Vaginitis	2.1%
346	Uterine Perforation	2.1%
347	Ovarian Hyperstimulation Syndrome	2.1%
348	Metrorrhagia	2.1%
349	Gestational Diabetes	2.1%
350	Mumps	2.1%
351	Bell Palsy	2%
352	Klinefelter Syndrome	2%
353	Lymphogranuloma Venereum	2%
354	Sezary Syndrome	2%
355	Respiratory Hypersensitivity	1.9%
356	Chickenpox	1.9%
357	Premature Ejaculation	1.9%
358	Sick Building Syndrome	1.9%
359	Erectile dysfunction	1.9%
360	Multiple Chemical Sensitivity	1.9%
361	Orchitis	1.9%
362	Plasmacytoma	1.9%
363	Tumor Lysis Syndrome	1.9%
364	Urticaria	1.9%
365	Vasculitis, Leukocytoclastic, Cutaneous	1.9%
366	HIV Infections	1.9%
367	Corpus Luteum Cyst	1.9%
368	Ovarian Cysts	1.9%
369	Anovulation	1.8%
370	Menorrhagia	1.8%
371	Premature Menopause	1.8%
372	Kernicterus	1.8%
373	Myasthenia Gravis, Autoimmune, Experimental	1.8%
374	Lymphoma	1.7%
375	Myasthenia Gravis	1.7%
376	Uveomeningoencephalitic Syndrome	1.7%
377	Mastocytosis	1.6%
378	Drug Eruptions	1.6%
379	Heavy Chain Disease	1.6%
380	Abortion, Habitual	1.6%
381	Dystocia	1.6%
382	Eclampsia	1.6%
383	Fetal Membranes, Premature Rupture	1.6%
384	Placental Insufficiency	1.6%
385	Pre-Eclampsia	1.6%
386	Prenatal Exposure Delayed Effects	1.6%
387	HELLP Syndrome	1.6%
388	Placenta, Retained	1.6%
389	Granulomatosis with polyangiitis	1.6%
390	Dermatitis, Allergic Contact	1.6%
391	Azoospermia	1.6%
392	Oligospermia	1.6%
393	Milk Allergy	1.6%
394	Impotence, Vasculogenic	1.6%
395	Asthenozoospermia	1.6%
396	Teratozoospermia	1.6%
397	Schnitzler Syndrome	1.6%
398	Wheat Hypersensitivity	1.6%
399	Aspermia	1.6%
400	Polycystic Ovary Syndrome	1.5%
401	Stiff-Person Syndrome	1.5%
402	Polyradiculoneuropathy	1.5%
403	Polyradiculoneuritis	1.5%
404	Cryoglobulinemia	1.5%
405	Felty Syndrome	1.5%
406	POEMS Syndrome	1.5%
407	Abortion, Veterinary	1.4%
408	Pregnancy Complications, Parasitic	1.4%
409	Lupus Vasculitis, Central Nervous System	1.4%
410	Lactation Disorder	1.4%
411	Mastitis	1.4%
412	Depression, Postpartum	1.4%
413	Embryo Loss	1.4%
414	Fetal Resorption	1.4%
415	Hyperemesis Gravidarum	1.4%
416	Mastocytosis, Systemic	1.4%
417	Neuromyelitis Optica	1.4%
418	Leukoencephalitis, Acute Hemorrhagic	1.4%
419	Leydig Cell Tumor	1.3%
420	Vasculitis, Central Nervous System	1.3%
421	Dermatitis, Atopic	1.3%
422	Rheumatoid Vasculitis	1.3%
423	Fetal Growth Retardation	1.2%
424	Trophoblastic Neoplasms	1.2%
425	Embolism, Amniotic Fluid	1.2%
426	Fetal Hypoxia	1.2%
427	Fetal Alcohol Spectrum Disorders	1.2%
428	Angioedema	1.2%
429	Multiple Sclerosis	1.2%
430	Breech Presentation	1.2%
431	Hodgkin Disease	1.2%
432	Leukemia, Plasma Cell	1.2%
433	Lymphoma, Non-Hodgkin	1.2%
434	Stillbirth	1.2%
435	Leukemia, T-Cell	1.2%
436	Acute Generalized Exanthematous Pustulosis	1.2%
437	Leukemia, B-Cell	1.2%
438	Lambert-Eaton Myasthenic Syndrome	1.2%
439	Waldenstrom Macroglobulinemia	1.2%
440	Sicca Syndrome	1.2%
441	Sjogren's Syndrome	1.2%
442	Asthma	1.1%
443	Composite Lymphoma	1.1%
444	Encephalomyelitis, Acute Disseminated	1.1%
445	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	1.1%
446	Erythema Nodosum	1.1%
447	Neuritis, Autoimmune, Experimental	1.1%
448	Premature Birth	1.1%
449	Dermatitis, Photoallergic	1.1%
450	Lymphangioleiomyomatosis	1.1%
451	Asthma, Exercise-Induced	1%
452	Status Asthmaticus	1%
453	Multiple Sclerosis, Chronic Progressive	1%
454	Multiple Sclerosis, Relapsing-Remitting	1%
455	Lymphoma, Follicular	1%
456	T-Cell Lymphoma	1%
457	Mantle cell lymphoma	1%
458	Meconium Aspiration Syndrome	1%
459	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1%
460	Leukemia, Large Granular Lymphocytic	1%
461	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1%
462	Aspergillosis, Allergic Bronchopulmonary	1%
463	Guillain-Barre Syndrome	1%
464	AIDS-Associated Nephropathy	1%
465	Asthma, Occupational	0.9%
466	Galactorrhea	0.9%
467	Herpes Zoster Oticus	0.9%
468	Farmer's Lung	0.9%
469	Angioedemas, Hereditary	0.9%
470	Hereditary Angioedema Type III	0.9%
471	Hereditary Angioedema Types I and II	0.9%
472	Lymphoma, T-Cell, Cutaneous	0.9%
473	Lymphoma, AIDS-Related	0.9%
474	Enteropathy-Associated T-Cell Lymphoma	0.9%
475	Primary Effusion Lymphoma	0.9%
476	Hay fever	0.9%
477	Rhinitis, Allergic, Perennial	0.9%
478	Toxic Epidermal Necrolysis	0.9%
479	Stevens-Johnson Syndrome	0.9%
480	Mycosis Fungoides	0.9%
481	Lymphomatoid Papulosis	0.9%
482	Plasmablastic lymphoma	0.9%
483	Lymphomatoid Granulomatosis	0.8%
484	Giant Cell Arteritis	0.8%
485	Temporal Arteritis	0.8%
486	Myelitis, Transverse	0.8%
487	Choriocarcinoma	0.7%
488	Miller Fisher Syndrome	0.6%
489	Hydatidiform Mole	0.6%

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