MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Candidiasis, Chronic Mucocutaneous

(UMLS:C0006845)

Definition:: A clinical syndrome characterized by development, usually in infancy or childhood, of a chronic, often widespread candidiasis of skin, nails, and mucous membranes. It may be secondary to one of the immunodeficiency syndromes, inherited as an autosomal recessive trait, or associated with defects in cell-mediated immunity, endocrine disorders, dental stomatitis, or malignancy.
UMLS ID:: C0006845
MeSH ID:: D002178

Classification 1:

Name:

Bacterial Infections and Mycoses
MeSH Tree Number(s):: C01.539.800.200.100|C01.703.160.165|C01.703.295.165

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.838.208.165

Synonym(s)

Candidiasis, Chronic Mucocutaneous

CHRONIC MUCOCUTANEOUS CANDIDOSIS

CMC - Chronic mucocutaneous candidiasis

Chronic Mucocutaneous Candidiasis

Chronic candidiasis of mucosa, skin and nails

Chronic mucocutaneous candidiasis

Mucocutaneous candidiasis

candidiasis chronic mucocutaneous

chronic mucocutaneous candidiasis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Ketoconazole		6320358	CTD
2	Miconazole		454066	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Cutaneous Candidiasis	62.3%
2	Chromoblastomycosis	50.9%
3	Dermatophytosis	50.9%
4	Sporotrichosis	50.9%
5	Tinea	50.9%
6	Tinea Versicolor	50.9%
7	Trichophytosis	50.9%
8	Hyalohyphomycosis	50.9%
9	Mycetoma	47.6%
10	Blastomycosis	44.7%
11	Fusariosis	38%
12	Tinea Capitis	37%
13	Onychomycosis	37%
14	Skin Diseases, Bacterial	31.9%
15	Tinea Pedis	31.7%
16	Candidemia	30.2%
17	Piedra	27.8%
18	Aspergillosis	27.3%
19	Coccidioidomycosis	27.3%
20	Histoplasmosis	27.3%
21	Paracoccidioidomycosis	27.3%
22	Zygomycosis	27.3%
23	Phaeohyphomycosis	27.3%
24	Pneumocystis Infections	27.3%
25	Neuroaspergillosis	25.4%
26	Hidradenitis Suppurativa	24.7%
27	Oral candidiasis	23.9%
28	Otomycosis	23%
29	Central Nervous System Fungal Infections	22.8%
30	Ecthyma	22.5%
31	Invasive Pulmonary Aspergillosis	22%
32	Erythema Chronicum Migrans	21.7%
33	Erysipelas	21.6%
34	Staphylococcal Skin Infections	21.6%
35	Cellulitis	21.2%
36	Erythrasma	21%
37	Fungemia	20.6%
38	Candidiasis, Vulvovaginal	20%
39	Lung Diseases, Fungal	19.9%
40	Bacterial Infections	19.9%
41	Meningitis, Cryptococcal	19.1%
42	Pelvic Infection	18%
43	Wound Infection	18%
44	Soft Tissue Infection	18%
45	Community-Acquired Infections	18%
46	Erythema Induratum	17.9%
47	Mucormycosis	17.8%
48	Impetigo	17.4%
49	Central Nervous System Infection	16.7%
50	Staphylococcal Scalded Skin Syndrome	16.4%
51	Central Nervous System Bacterial Infections	16.3%
52	Bacteremia	16.1%
53	Ulcerative stomatitis	15.7%
54	Rhinoscleroma	15.6%
55	Eye Infection	15.5%
56	Respiratory Tract Infections	15.5%
57	Candidiasis	15.3%
58	Bone Diseases, Infectious	15.2%
59	Pregnancy Complications, Infectious	15.2%
60	Arthritis, Infectious	15%
61	Suppuration	15%
62	Cross Infection	14.9%
63	Septicemia	14.9%
64	Sepsis	14.9%
65	Pulmonary Aspergillosis	14.8%
66	Bronchopulmonary Aspergillosis	14.8%
67	Dermatomycoses	14.8%
68	Candidiasis, Chronic Mucocutaneous	14.8%
69	Furunculosis	14.7%
70	furuncle	14.7%
71	Bacterial Endocarditis	14.3%
72	Panophthalmitis	13.8%
73	carbuncle	13.8%
74	Infection	13.7%
75	Opportunistic Infections	13.6%
76	Endotoxemia	13.5%
77	Urinary tract infection	13%
78	Pyoderma Gangrenosum	12.7%
79	Syphilis	12.7%
80	Meningitis, Fungal	12.7%
81	Borrelia Infections	12.1%
82	Leptospirosis	12.1%
83	Brain Abscess	12%
84	Pertussis	11.8%
85	Sexually Transmitted Diseases	11.6%
86	Gram-Negative Bacterial Infections	11.3%
87	Gram-Positive Bacterial Infections	11.3%
88	Subacute Bacterial Endocarditis	11.3%
89	Lupus Erythematosus, Cutaneous	11.2%
90	Panniculitis	11.2%
91	Systemic Scleroderma	11.2%
92	Morphea	11.2%
93	Chlamydia Infections	11.2%
94	Gonorrhea	11.2%
95	Lyme Disease	11.2%
96	Relapsing Fever	11.2%
97	Lyme Neuroborreliosis	11%
98	Joint Tuberculosis	10.6%
99	Tuberculosis, Osteoarticular	10.6%
100	Bone Tuberculosis	10.6%
101	Breast Diseases	10%
102	Dermatitis	10%
103	Exanthema	10%
104	Facial Dermatoses	10%
105	Hair Diseases	10%
106	Hand Dermatoses	10%
107	keratoacanthoma	10%
108	Keratosis	10%
109	Nail Diseases	10%
110	Photosensitivity Disorders	10%
111	Prurigo	10%
112	Pyoderma	10%
113	Rosacea	10%
114	Sebaceous Gland Diseases	10%
115	Skin Diseases, Vesiculobullous	10%
116	Skin Ulcer	10%
117	Sweat Gland Diseases	10%
118	Xeroderma Pigmentosum	10%
119	Skin Diseases, Papulosquamous	10%
120	Skin Diseases, Vascular	10%
121	Acneiform Eruptions	10%
122	Ocular Rosacea	10%
123	Subcorneal pustular dermatosis	10%
124	Erythematotelangiectatic Rosacea	10%
125	Papulopustular Rosacea	10%
126	Chronic Actinic Dermatitis	10%
127	Dermatitis, Atopic	9.9%
128	Epidermolysis Bullosa	9.9%
129	Acne Vulgaris	9.9%
130	Contact Dermatitis	9.9%
131	Eczema	9.9%
132	Erythema Multiforme	9.9%
133	Intertrigo	9.9%
134	Neurodermatitis	9.9%
135	Rhinophyma	9.9%
136	Perioral Dermatitis	9.9%
137	Acne	9.9%
138	Neurosyphilis	9.8%
139	Hordeolum	9.5%
140	Erythema Infectiosum	9.5%
141	Exanthema Subitum	9.5%
142	Bacterial conjunctivitis	9.5%
143	Endophthalmitis	9.4%
144	Peritonitis	9.4%
145	Bacterial Vaginosis	9.4%
146	Osteomyelitis	9.3%
147	Periostitis	9.3%
148	Surgical Wound Infection	9.3%
149	Abscess	9.3%
150	Adnexitis	9.3%
151	Empyema	9.3%
152	Pelvic Inflammatory Disease	9.3%
153	Human Ehrlichiosis	8.7%
154	Foot Diseases	8.6%
155	Lymphogranuloma Venereum	8.6%
156	Dermatitis Herpetiformis	8.6%
157	Acrodermatitis	8.5%
158	Sebaceous Gland Neoplasms	8.5%
159	Porokeratosis	8.5%
160	Gianotti-Crosti Syndrome	8.5%
161	Keratoderma, Palmoplantar	8.5%
162	Skin Abnormalities	8.4%
163	Skin Neoplasms	8.4%
164	Pigmentation Disorders	8.4%
165	Dermatitis, Phototoxic	8.4%
166	Pityriasis Lichenoides et Varioliformis Acuta	8.4%
167	Pityriasis Lichenoides	8.4%
168	Phototoxicity	8.4%
169	Lipomatosis	8.3%
170	Pruritus	8.3%
171	Erythema	8.3%
172	Necrolytic Migratory Erythema	8.3%
173	Cutaneous Fistula	8.3%
174	Nephrogenic Fibrosing Dermopathy	8.3%
175	Nephrogenic Systemic Fibrosis	8.3%
176	Dermatomyositis	8.3%
177	Necrobiosis Lipoidica Diabeticorum	8.2%
178	Panniculitis, Lupus Erythematosus	8.2%
179	Foot Ulcer	8.2%
180	Superinfection	8.2%
181	Pneumonia, Bacterial	8.1%
182	Corneal Ulcer	8.1%
183	Puerperal Infection	8%
184	Spondylitis	8%
185	Appendicitis	8%
186	Bacteriuria	8%
187	Pyuria	8%
188	Pyomyositis	8%
189	Endotoxic shock	7.9%
190	Septic Shock	7.9%
191	Toxic Shock Syndrome	7.9%
192	Japanese Spotted Fever	7.9%
193	Ophthalmia Neonatorum	7.8%
194	Trachoma	7.8%
195	Psoas Abscess	7.8%
196	Abdominal Abscess	7.8%
197	Human anaplasmosis	7.7%
198	Lice Infestations	7.7%
199	Xeroderma	7.5%
200	Aspergillosis, Allergic Bronchopulmonary	7.3%
201	Dermatitis, Photoallergic	7.3%
202	Actinomycetales Infections	7.2%
203	Bordetella Infections	7.2%
204	Brucellosis	7.2%
205	Campylobacter infection	7.2%
206	Clostridium Infections	7.2%
207	Enterobacteriaceae Infections	7.2%
208	Listeriosis	7.2%
209	Pseudomonas Infections	7.2%
210	Q Fever	7.2%
211	Staphylococcal Infections	7.2%
212	Streptococcal Infections	7.2%
213	Vibrio Infections	7.2%
214	Helicobacter Infections	7.2%
215	Bacillaceae Infections	7.2%
216	Neisseriaceae Infections	7.2%
217	Burkholderia Infections	7.2%
218	Clostridium difficile infection	7.2%
219	Flavobacteriaceae Infections	7.2%
220	Moraxellaceae Infections	7.2%
221	Burkholderia cepacia Infection	7.2%
222	Mastocytosis	7.1%
223	Tuberculosis, Spinal	7%
224	Urticaria Pigmentosa	7%
225	Pseudoxanthoma Elasticum	6.9%
226	Arthritis, Reactive	6.9%
227	Skin Diseases, Infectious	6.7%
228	Cutis Laxa	6.7%
229	Larva Migrans	6.6%
230	Leishmaniasis	6.6%
231	Molluscum Contagiosum	6.6%
232	Ectodermal Dysplasia	6.6%
233	Aplasia Cutis Congenita	6.6%
234	Rocky Mountain Spotted Fever	6.6%
235	Lupus Erythematosus, Discoid	6.6%
236	Scleroderma, Limited	6.6%
237	Onchocerciasis	6.6%
238	Diverticulitis	6.5%
239	Dermatitis, Irritant	6.5%
240	Acne Conglobata	6.5%
241	Meningitis, Listeria	6.5%
242	AIDS-Related Opportunistic Infections	6.3%
243	Erysipelothrix infection	6.2%
244	Connective Tissue Diseases	6.2%
245	Mycoses	6.2%
246	Erythema Nodosum	6.1%
247	Syphilis, Congenital	6.1%
248	Toxoplasmosis, Cerebral	6.1%
249	Anhidrosis	5.9%
250	Cholesteatoma	5.9%
251	Pressure Ulcer	5.9%
252	Folliculitis	5.9%
253	Foot Dermatoses	5.9%
254	Gynecomastia	5.9%
255	Hypertrichosis	5.9%
256	Hypohidrosis	5.9%
257	Hypotrichosis	5.9%
258	Leg Ulcer	5.9%
259	Miliaria	5.9%
260	Parakeratosis	5.9%
261	Parapsoriasis	5.9%
262	Pityriasis	5.9%
263	Psoriasis	5.9%
264	Sweet Syndrome	5.9%
265	Hidradenitis	5.9%
266	Onycholysis	5.9%
267	Miliaria Rubra	5.9%
268	Hyperpigmentation	5.9%
269	Lichenoid Eruptions	5.9%
270	Chloracne	5.9%
271	Meningitis, Haemophilus	5.9%
272	Meningitis, Pneumococcal	5.9%
273	Toxic Epidermal Necrolysis	5.9%
274	Stevens-Johnson Syndrome	5.9%
275	Warts	5.9%
276	Dermatitis, Occupational	5.8%
277	Lung Abscess	5.7%
278	Diverticulum	5.7%
279	Diverticulosis	5.7%
280	Dermatitis, Allergic Contact	5.6%
281	Discitis	5.6%
282	Mastoiditis	5.6%
283	Papillon-Lefevre Disease	5.6%
284	Petrositis	5.6%
285	Ichthyosis, X-Linked	5.3%
286	Sjogren-Larsson Syndrome	5.3%
287	Liver Abscess	5.2%
288	Acinetobacter Infections	5.2%
289	Actinomycosis	5.2%
290	Bacteroides Infections	5.2%
291	Cholera	5.2%
292	Corynebacterium Infections	5.2%
293	Escherichia coli Infections	5.2%
294	Gas Gangrene	5.2%
295	Haemophilus Infections	5.2%
296	Klebsiella Infections	5.2%
297	Meningococcal Infections	5.2%
298	Mycobacterium Infections	5.2%
299	Mycoplasma Infections	5.2%
300	Nocardia Infections	5.2%
301	Pasteurella Infections	5.2%
302	Pneumococcal Infections	5.2%
303	Proteus Infections	5.2%
304	Rickettsia Infections	5.2%
305	Salmonella infections	5.2%
306	Scarlet Fever	5.2%
307	Scrub Typhus	5.2%
308	Tetanus	5.2%
309	Serratia Infections	5.2%
310	Ureaplasma Infections	5.2%
311	Pulmonary Nocardiosis	5.2%
312	Granuloma Annulare	5.2%
313	Meningitis, Bacterial	5.2%
314	Acantholysis	5%
315	Breast Cyst	5%
316	Actinic keratosis	5%
317	Pemphigoid, Benign Mucous Membrane	5%
318	Pemphigus	5%
319	Sunburn	5%
320	Behcet Syndrome	5%
321	Argyria	4.9%
322	Hirsutism	4.9%
323	Lactation Disorder	4.9%
324	Mastitis	4.9%
325	Urticaria	4.9%
326	Retropharyngeal Abscess	4.9%
327	Adiposis Dolorosa	4.9%
328	Pruritus Vulvae	4.9%
329	Epidural Abscess	4.9%
330	Mastocytoma	4.9%
331	Pruritus Ani	4.9%
332	Leishmaniasis, Cutaneous	4.9%
333	Eczema Herpeticum	4.9%
334	Peritonsillar Abscess	4.9%
335	Diaper Rash	4.9%
336	Hyperkeratosis, Epidermolytic	4.8%
337	Tuberculosis, Meningeal	4.8%
338	Albinism	4.5%
339	Epidermodysplasia Verruciformis	4.3%
340	Herpes Labialis	4.3%
341	Mucocutaneous Lymph Node Syndrome	4.3%
342	Drug Eruptions	4.2%
343	Lipodystrophy	4.2%
344	Livedo Reticularis	4.2%
345	Malignant Atrophic Papulosis	4.2%
346	Diphtheria	4.2%
347	Leprosy	4.2%
348	Mycobacterium Infections, Nontuberculous	4.2%
349	Psittacosis	4.2%
350	Paratyphoid Fever	4.2%
351	Plague	4.2%
352	Tuberculosis	4.2%
353	Typhoid Fever	4.2%
354	TYPHUS	4.2%
355	Yersinia pseudotuberculosis Infections	4.2%
356	Bubonic Plague	4.2%
357	Mycobacterium abscessus Infection	4.2%
358	Polyarteritis Nodosa	4.2%
359	Takayasu Arteritis	4.2%
360	Lichen Planus	3.9%
361	Melanosis	3.9%
362	Chloasma	3.9%
363	Pityriasis Rosea	3.9%
364	Pityriasis Rubra Pilaris	3.9%
365	Vitiligo	3.9%
366	Lichen Nitidus	3.9%
367	Condylomata Acuminata	3.8%
368	Rheumatic Fever	3.8%
369	Nail-Patella Syndrome	3.8%
370	Porphyrias, Hepatic	3.7%
371	Mycobacterium avium-intracellulare Infection	3.7%
372	Lymph Node Tuberculosis	3.7%
373	Tuberculosis, Miliary	3.7%
374	Tuberculosis, Multidrug-Resistant	3.7%
375	Leprosy, Multibacillary	3.7%
376	Latent Tuberculosis	3.7%
377	Enterocolitis, Pseudomembranous	3.7%
378	pseudomembranous colitis	3.7%
379	Dysentery, Bacillary	3.7%
380	Salmonella Infections, Animal	3.7%
381	Rheumatic Heart Disease	3.6%
382	Salmonella food poisoning	3.5%
383	Borderline leprosy	3.5%
384	Leprosy, Lepromatous	3.5%
385	Tuberculoid leprosy	3.5%
386	Extensively Drug-Resistant Tuberculosis	3.5%
387	Collagen Diseases	3.3%
388	Mixed Connective Tissue Disease	3.3%
389	Mucinoses	3.3%
390	Botulism	3.3%
391	Alopecia	3.3%
392	Sweating, Gustatory	3.3%
393	Androgenetic Alopecia	3.3%
394	Auriculotemporal Syndrome	3.3%
395	Varicose Ulcer	3.3%
396	Breast Neoplasms, Male	3.3%
397	Triple Negative Breast Neoplasms	3.3%
398	Galactorrhea	3.3%
399	Tuberculosis, Gastrointestinal	3.2%
400	Tuberculosis, Central Nervous System	3.1%
401	Waterhouse-Friderichsen Syndrome	3.1%
402	Liver Abscess, Amebic	3%
403	Acanthosis Nigricans	2.9%
404	Alopecia Areata	2.9%
405	Lentigo	2.9%
406	Cartilage Diseases	2.9%
407	Rheumatism	2.9%
408	Chondromalacia	2.9%
409	Angioedema	2.8%
410	Lupus Erythematosus, Systemic	2.8%
411	Overlap syndrome	2.8%
412	Acute Generalized Exanthematous Pustulosis	2.8%
413	Tuberculosis, Pulmonary	2.7%
414	Giant Cell Arteritis	2.7%
415	Temporal Arteritis	2.7%
416	CREST Syndrome	2.6%
417	Lichen Planus, Oral	2.5%
418	Serum Sickness	2.4%
419	Variegate Porphyria	2.4%
420	Acute intermittent porphyria	2.4%
421	Porphyria Cutanea Tarda	2.4%
422	Carcinoma, Lobular	2.4%
423	Arthritis, Psoriatic	2.4%
424	Dupuytren Contracture	2.4%
425	Lemierre Syndrome	2.1%
426	Menkes Kinky Hair Syndrome	2.1%
427	Scleromyxedema	2%
428	Tuberculosis, Renal	2%
429	HIV-Associated Lipodystrophy Syndrome	2%
430	Angioedemas, Hereditary	1.9%
431	Diabetic Foot	1.8%
432	Hereditary Angioedema Type III	1.7%
433	Hereditary Angioedema Types I and II	1.7%
434	Mesenteric Panniculitis	1.7%
435	Panniculitis, Peritoneal	1.7%
436	Tietze's Syndrome	1.7%
437	Orbital Cellulitis	1.7%
438	Myxoid cyst	1.7%
439	Noonan Syndrome	1.7%
440	Myxedema	1.6%
441	Peutz-Jeghers Syndrome	1.5%
442	Marfan Syndrome	1.5%
443	Homocystinuria	1.5%
444	Osteochondritis	1.4%
445	Polymyalgia Rheumatica	1.4%
446	Osteogenesis Imperfecta	1.4%
447	Keloid	1.4%
448	Rheumatoid Arthritis	1.3%
449	Juvenile arthritis	1.3%
450	Lupus Nephritis	1.2%
451	Laryngomalacia	1.1%
452	Pectus carinatum	1.1%
453	Rheumatoid Nodule	0.9%
454	Felty Syndrome	0.8%
455	Bronchomalacia	0.8%
456	Tracheomalacia	0.8%
457	Rheumatoid Vasculitis	0.7%
458	Mucopolysaccharidosis III	0.7%
459	Sicca Syndrome	0.7%
460	Sjogren's Syndrome	0.7%
461	Lupus Vasculitis, Central Nervous System	0.7%
462	Mucopolysaccharidosis II	0.5%

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