MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Status Asthmaticus

(UMLS:C0038218)

Definition:: A sudden intense and continuous aggravation of a state of asthma, marked by dyspnea to the point of exhaustion and collapse and not responding to the usual therapeutic efforts.
UMLS ID:: C0038218
MeSH ID:: D013224

Classification 1:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.127.108.880|C08.674.095.880

Classification 2:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.480.680.095.880

Synonym(s)

Status Asthmaticus

ASTHMA WITH STATUS ASTHMATICUS

Acute severe asthma

Acute severe exacerbation of asthma

Asthma with status asthmaticus

Asthma, unspecified type, with status asthmaticus

Asthmatic crisis

Status asthmaticus

acute severe asthma

10.

asthma asthmaticus status

11.

asthma with acute exacerbation severe

12.

asthma with acute severe exacerbation

13.

asthma with status asthmaticus

14.

asthmatic crisis

15.

asthmaticus status

16.

asthmaticus; status

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Fluticasone-Salmeterol Drug Combination	FAERS: 8		US FAERS
2	Alendronate	FAERS: 7		US FAERS
3	montelukast	FAERS: 6 Canada Vigilance: 1		Canada Vigilance US FAERS
4	Salmeterol Xinafoate	FAERS: 4		US FAERS
5	Arthrotec	FAERS: 3		US FAERS
6	Acetylcysteine	FAERS: 2		US FAERS
7	Aspirin	FAERS: 2		US FAERS
8	Celecoxib	FAERS: 2		US FAERS
9	Dextromethorphan	FAERS: 2		US FAERS
10	Diclofenac	FAERS: 2		US FAERS
11	Ibandronic Acid	FAERS: 2		US FAERS
12	Ibuprofen	FAERS: 2		US FAERS
13	Milnacipran	FAERS: 2		US FAERS
14	almotriptan	FAERS: 2		US FAERS
15	dorzolamide	FAERS: 2		US FAERS
16	rofecoxib	FAERS: 2		US FAERS
17	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
18	Albuterol	FAERS: 1		US FAERS
19	Albuterol	FAERS: 1	114264 7427548	CTD US FAERS
20	Aspirin-oxycodone hydrochloride-oxycodone terephthalate combination	FAERS: 1		US FAERS
21	Azithromycin	FAERS: 1		US FAERS
22	Ceftriaxone	FAERS: 1		US FAERS
23	Duloxetine Hydrochloride	FAERS: 1		US FAERS
24	Epinephrine	FAERS: 1	19204641	CTD US FAERS
25	Fentanyl	FAERS: 1		US FAERS
26	Iopamidol	FAERS: 1		US FAERS
27	Ipratropium	FAERS: 1		US FAERS
28	Ketoprofen	FAERS: 1		US FAERS
29	Lamotrigine	FAERS: 1		US FAERS
30	Levalbuterol	FAERS: 1		US FAERS
31	Levofloxacin	FAERS: 1		US FAERS
32	Lidoderm	FAERS: 1		US FAERS
33	Loratadine	FAERS: 1		US FAERS
34	Methylprednisolone Hemisuccinate	FAERS: 1		US FAERS
35	Mometasone Furoate	FAERS: 1		US FAERS
36	Morphine	FAERS: 1		US FAERS
37	Naproxen	FAERS: 1		US FAERS
38	Nebivolol	FAERS: 1		US FAERS
39	Norgestrel	FAERS: 1		US FAERS
40	Paclitaxel	FAERS: 1		US FAERS
41	Pregabalin	FAERS: 1		US FAERS
42	Tacrolimus	FAERS: 1		US FAERS
43	Teriparatide	FAERS: 1		US FAERS
44	Triamcinolone Acetonide	FAERS: 1		US FAERS
45	Valsartan	FAERS: 1		US FAERS
46	aclidinium bromide	FAERS: 1		US FAERS
47	ambrisentan	FAERS: 1		US FAERS
48	carbidopa, levodopa drug combination	FAERS: 1		US FAERS
49	etonogestrel	FAERS: 1		US FAERS
50	gadobenic acid	FAERS: 1		US FAERS
51	indacaterol	FAERS: 1		US FAERS
52	iopromide	FAERS: 1		SIDER US FAERS
53	Aminophylline		114264 1289633 7427548	CTD
54	Ampicillin		114264	CTD
55	Atenolol			SIDER
56	Atracurium		1763262	CTD
57	Beclomethasone		114264	CTD
58	Diphenhydramine	Canada Vigilance: 1		Canada Vigilance
59	Enflurane		2145134	CTD
60	Halothane		2145134	CTD
61	Hydrocortisone		View details 114264 7427239 7427548 10689850	CTD
62	Ipratropium			SIDER
63	Isoflurane		17251884	CTD
64	Isoproterenol		641628 3109801 5067981	CTD
65	Ketamine		8086092 19204641	CTD
66	Lorazepam		7427548	CTD
67	Methylprednisolone		1289633 1356045 8023076	CTD
68	Metoprolol			SIDER
69	Naproxen	Canada Vigilance: 1		Canada Vigilance
70	Octreotide			SIDER
71	Pancuronium		1763262 7427548 8023076	CTD
72	Phenoperidine		7427548	CTD
73	Prednisolone		114264	CTD
74	Terbutaline		7427548	CTD
75	Timolol		7219583	CTD
76	Trimethoprim, Sulfamethoxazole Drug Combination		7427548	CTD
77	Vecuronium Bromide		1356045	CTD
78	hydrocortisone sodium phosphate		4714859	CTD
79	iotrolan			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Asthma, Exercise-Induced	51.9%
2	Asthma, Occupational	45.9%
3	Asthma, Aspirin-Induced	36.9%
4	Aspergillosis, Allergic Bronchopulmonary	24.9%
5	Bronchitis	24.8%
6	Tracheobronchomegaly	23.4%
7	Bronchopneumonia	22.3%
8	Bronchial Fistula	20.2%
9	Bronchospasm	20.1%
10	Bronchiectasis	20.1%
11	Bronchial Hyperreactivity	20.1%
12	Bronchial Neoplasms	17.7%
13	Farmer's Lung	17.5%
14	Lung diseases	17.3%
15	Pleural Diseases	17.3%
16	Respiration Disorders	17.3%
17	Thoracic Diseases	17.3%
18	Tracheal Diseases	17.3%
19	Hay fever	17.2%
20	Rhinitis, Allergic, Perennial	17.2%
21	Bronchitis, Chronic	16.9%
22	Bronchiolitis	16.4%
23	Pleurisy	16.3%
24	Pneumonia	16.3%
25	Lobar Pneumonia	16.3%
26	Respiratory Distress Syndrome, Adult	16.3%
27	Tracheitis	16.3%
28	Pneumonitis	16.3%
29	Pleuropneumonia	15.1%
30	anaphylaxis	14.4%
31	Food Allergy	14.4%
32	Anaphylactic shock	14.4%
33	Laryngeal Diseases	14.3%
34	Nose Diseases	14.3%
35	Respiratory Tract Infections	13.9%
36	Granuloma, Respiratory Tract	13.7%
37	Respiratory Tract Fistula	13.7%
38	Laryngitis	13.7%
39	Lung Diseases, Fungal	13.7%
40	Rhinitis	13.7%
41	Vocal Cord Dysfunction	13.7%
42	Granuloma, Laryngeal	13.5%
43	Respiratory Distress Syndrome, Newborn	13.5%
44	Lung Abscess	13.4%
45	Lung Neoplasms	13.4%
46	Pleural Neoplasms	13.4%
47	Tuberculosis, Pulmonary	13.4%
48	Choanal Atresia	11.7%
49	Laryngocele	11.7%
50	Urticaria	11.6%
51	Tracheal Neoplasms	11.5%
52	Immune Complex Diseases	11.3%
53	Latex allergy	11.3%
54	Pleural Effusion, Malignant	11.3%
55	Sinusitis	11.1%
56	Bronchiolitis Obliterans	11%
57	Aspiration Pneumonia	10.6%
58	Laryngeal neoplasm	10.2%
59	Altitude Sickness	10%
60	Atelectasis	10%
61	Chylothorax	10%
62	Hydropneumothorax	10%
63	Hydrothorax	10%
64	Pulmonary Hypertension	10%
65	Pneumothorax	10%
66	Pulmonary Alveolar Proteinosis	10%
67	Pulmonary Edema	10%
68	Pulmonary Fibrosis	10%
69	Respiratory Insufficiency	10%
70	Tracheal Stenosis	10%
71	Hamman-Rich syndrome	10%
72	Lung Diseases, Interstitial	10%
73	Respiratory Depression	10%
74	Lung Diseases, Obstructive	10%
75	Respiratory Failure	10%
76	Primary Ciliary Dyskinesia	10%
77	Asthma	9.6%
78	Environmental Illness	9.4%
79	Idiopathic Pulmonary Fibrosis	9.2%
80	Pneumoconiosis	9.1%
81	Pneumonia, Viral	9.1%
82	Scimitar Syndrome	9%
83	Pneumonia, Bacterial	8.9%
84	Kartagener Syndrome	8.9%
85	Laryngospasm	8.8%
86	Acute Chest Syndrome	8.8%
87	Hyaline Membrane Disease	8.8%
88	Multiple Pulmonary Nodules	8.7%
89	Bronchial Diseases	8.7%
90	Milk Allergy	8.6%
91	Wheat Hypersensitivity	8.6%
92	Meconium Aspiration Syndrome	8.5%
93	Granuloma, Lethal Midline	8.1%
94	Laryngeal Edema	8.1%
95	Nose Deformities, Acquired	8.1%
96	Lung Injury	8.1%
97	Hepatopulmonary Syndrome	8.1%
98	Respiratory Aspiration	8.1%
99	Nose Neoplasms	8.1%
100	Apnea	8%
101	Cheyne-Stokes Respiration	8%
102	Common Cold	8%
103	Dyspnea	8%
104	Hemothorax	8%
105	Hyperventilation	8%
106	Influenza	8%
107	Mouth Breathing	8%
108	Rhinoscleroma	8%
109	Tachypnea	8%
110	Catarrh	8%
111	Pulmonary Embolism	8%
112	Pulmonary Eosinophilia	7.9%
113	Severe Acute Respiratory Syndrome	7.9%
114	Eosinophilic Pneumonia	7.9%
115	Laryngopharyngeal Reflux	7.9%
116	Paranasal Sinus Neoplasms	7.9%
117	Pneumonia, Lipid	7.8%
118	Radiation Pneumonitis	7.6%
119	Radiation Fibrosis	7.6%
120	Kounis Syndrome	7.5%
121	Bronchomalacia	7.5%
122	Hoarseness	7.4%
123	Autoimmune Diseases	7.4%
124	Immunologic Deficiency Syndromes	7.4%
125	Immunoproliferative Disorders	7.4%
126	Immune reconstitution syndrome	7.4%
127	Immune Reconstitution Inflammatory Syndrome	7.4%
128	Dermatitis, Atopic	7.2%
129	Respiratory Hypersensitivity	6.9%
130	Pharyngitis	6.8%
131	Laryngostenosis	6.8%
132	Nasal Polyps	6.8%
133	Hemoptysis	6.7%
134	Pertussis	6.6%
135	Asbestosis	6.6%
136	Berylliosis	6.6%
137	Silicosis	6.6%
138	Airway Obstruction	6.6%
139	Choking	6.6%
140	Epiglottitis	6.6%
141	Chronic Obstructive Airway Disease	6.6%
142	Mediastinitis	6.6%
143	Middle Lobe Syndrome	6.6%
144	Acute Lung Injury	6.6%
145	Transfusion Reaction	5.9%
146	Hypotensive Transfusion Reaction	5.9%
147	Cystic Fibrosis	5.9%
148	Anti-Glomerular Basement Membrane Disease	5.9%
149	Blastomycosis	5.9%
150	Voice Disorders	5.8%
151	Voice Disturbance	5.8%
152	Maxillary Sinus Neoplasms	5.8%
153	Transfusion-Related Acute Lung Injury	5.8%
154	Angioedema	5.8%
155	Epistaxis	5.8%
156	Granulomatosis with polyangiitis	5.7%
157	Serum Sickness	5.6%
158	Mediastinal Cyst	5.4%
159	Pericardial Cyst	5.4%
160	Persistent Fetal Circulation Syndrome	5.4%
161	Thymic Cyst	5.4%
162	Croup	5.3%
163	Histiocytosis, Langerhans-Cell	5.3%
164	Mediastinal Emphysema	5.3%
165	Rhinitis, Vasomotor	5.3%
166	Pulmonary Aspergillosis	5.3%
167	Bronchopulmonary Aspergillosis	5.3%
168	Hypoventilation	5.3%
169	Acidosis, Respiratory	5.2%
170	Alkalosis, Respiratory	5.2%
171	Sarcoidosis, Pulmonary	5.2%
172	Sleep Apnea Syndromes	5.2%
173	Pulmonary Infarction	5.2%
174	Laryngomalacia	5.1%
175	Vocal Cord Paralysis	5%
176	Sick Building Syndrome	5%
177	Multiple Chemical Sensitivity	5%
178	Vasculitis, Leukocytoclastic, Cutaneous	5%
179	Pulmonary Emphysema	4.9%
180	Glomerulonephritis, Membranoproliferative	4.8%
181	Tonsillitis	4.4%
182	Dyspnea, Paroxysmal	4.4%
183	Respiratory Paralysis	4.4%
184	Status Asthmaticus	4.4%
185	Mastocytosis	4.2%
186	Drug Eruptions	4.1%
187	Dermatitis, Allergic Contact	4.1%
188	Bronchopulmonary Dysplasia	3.9%
189	Sleep Apnea, Obstructive	3.9%
190	Sleep Apnea, Central	3.9%
191	Antiphospholipid Syndrome	3.8%
192	Aphonia	3.8%
193	Retropharyngeal Abscess	3.8%
194	Dysphonia	3.8%
195	Tracheomalacia	3.7%
196	Thrombocytopenic purpura	3.5%
197	Autoimmune Lymphoproliferative Syndrome	3.4%
198	Nasopharyngitis	3.3%
199	Angioedemas, Hereditary	3.3%
200	Invasive Pulmonary Aspergillosis	3.3%
201	Lupus Erythematosus, Systemic	3.1%
202	Lymphoproliferative Disorders	3.1%
203	Overlap syndrome	3.1%
204	Addison Disease	3%
205	Paraproteinemias	3%
206	Pemphigus	3%
207	Autoimmune thyroiditis	3%
208	Primary Adrenal Insufficiency	3%
209	Lymphopenia	3%
210	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	3%
211	Autoimmune hepatitis	3%
212	Autoimmune thrombocytopenia	3%
213	Immune thrombocytopenic purpura	3%
214	Mastocytosis, Systemic	2.9%
215	Hereditary Angioedema Type III	2.8%
216	Hereditary Angioedema Types I and II	2.8%
217	Peritonsillar Abscess	2.8%
218	Hypergammaglobulinemia	2.5%
219	Latent Autoimmune Diabetes in Adults	2.5%
220	Agammaglobulinemia	2.5%
221	Dermatitis Herpetiformis	2.5%
222	HIV Infections	2.5%
223	Eosinophilic Granuloma	2.5%
224	Acute Generalized Exanthematous Pustulosis	2.4%
225	Primary amyloidosis	2.4%
226	Monoclonal Gammopathy of Undetermined Significance	2.3%
227	Rheumatoid Arthritis	2.2%
228	Juvenile arthritis	2.2%
229	Graves Disease	2.1%
230	Erythema Nodosum	2.1%
231	Dermatitis, Photoallergic	2.1%
232	Multiple Myeloma	1.8%
233	Kernicterus	1.7%
234	Plasmacytoma	1.7%
235	Tumor Lysis Syndrome	1.7%
236	HTLV-I Infections	1.6%
237	Job Syndrome	1.6%
238	Toxic Epidermal Necrolysis	1.6%
239	Stevens-Johnson Syndrome	1.6%
240	Ataxia Telangiectasia	1.5%
241	Hydrops Fetalis	1.5%
242	Lymphoma	1.4%
243	Myasthenia Gravis	1.4%
244	Uveomeningoencephalitic Syndrome	1.4%
245	Chronic granulomatous disease	1.4%
246	Heavy Chain Disease	1.4%
247	HIV Seropositivity	1.4%
248	Sezary Syndrome	1.3%
249	Schnitzler Syndrome	1.2%
250	Stiff-Person Syndrome	1.2%
251	Polyradiculoneuropathy	1.2%
252	Polyradiculoneuritis	1.2%
253	Acquired Immunodeficiency Syndrome	1.2%
254	AIDS related complex	1.2%
255	Infectious Mononucleosis	1.2%
256	Cryoglobulinemia	1.2%
257	Felty Syndrome	1.2%
258	POEMS Syndrome	1.2%
259	Lupus Nephritis	1.2%
260	Myasthenia Gravis, Autoimmune, Experimental	1.1%
261	AIDS-Related Opportunistic Infections	1%
262	Vasculitis, Central Nervous System	1%
263	HIV Wasting Syndrome	1%
264	Rheumatoid Vasculitis	1%
265	AIDS Dementia Complex	1%
266	AIDS-Associated Nephropathy	1%
267	Lupus Vasculitis, Central Nervous System	0.9%
268	Lambert-Eaton Myasthenic Syndrome	0.9%
269	Waldenstrom Macroglobulinemia	0.9%
270	Wiskott-Aldrich Syndrome	0.9%
271	Sicca Syndrome	0.9%
272	Sjogren's Syndrome	0.9%
273	HIV-Associated Lipodystrophy Syndrome	0.9%
274	Multiple Sclerosis	0.8%
275	Hodgkin Disease	0.8%
276	Leukemia, Plasma Cell	0.8%
277	Lymphoma, Non-Hodgkin	0.8%
278	Leukemia, T-Cell	0.8%
279	Leukemia, B-Cell	0.8%
280	Neuromyelitis Optica	0.7%
281	Leukoencephalitis, Acute Hemorrhagic	0.7%
282	Composite Lymphoma	0.7%
283	Encephalomyelitis, Acute Disseminated	0.7%
284	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	0.7%
285	Neuritis, Autoimmune, Experimental	0.7%
286	Lymphangioleiomyomatosis	0.7%
287	Guillain-Barre Syndrome	0.6%
288	Multiple Sclerosis, Chronic Progressive	0.5%
289	Multiple Sclerosis, Relapsing-Remitting	0.5%
290	Lymphoma, Follicular	0.5%
291	T-Cell Lymphoma	0.5%
292	Mantle cell lymphoma	0.5%
293	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
294	Leukemia, Large Granular Lymphocytic	0.5%
295	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.5%
296	Giant Cell Arteritis	0.5%
297	Temporal Arteritis	0.5%
298	Myelitis, Transverse	0.4%
299	Lymphoma, T-Cell, Cutaneous	0.4%
300	Lymphoma, AIDS-Related	0.4%
301	Enteropathy-Associated T-Cell Lymphoma	0.4%
302	Primary Effusion Lymphoma	0.4%
303	Lymphomatoid Granulomatosis	0.3%
304	Mycosis Fungoides	0.3%
305	Lymphomatoid Papulosis	0.3%
306	Plasmablastic lymphoma	0.3%
307	Burkitt Lymphoma	0.3%
308	Miller Fisher Syndrome	0.3%

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