MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Mastocytosis

(UMLS:C0024899)

Definition:: A heterogenous group of disorders characterized by the abnormal increase of MAST CELLS in only the skin (MASTOCYTOSIS, CUTANEOUS), in extracutaneous tissues involving multiple organs (MASTOCYTOSIS, SYSTEMIC), or in solid tumors (MASTOCYTOMA).
UMLS ID:: C0024899
MeSH ID:: D008415

Classification 1:

Name:

Neoplasms
MeSH Tree Number(s):: C04.557.450.565.465

Classification 2:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.508

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.520.350

Synonym(s)

Mastocytosis

Congenital cutaneous mastocytosis

MASTOCYTOSIS

Mast Cell Disease

Mast cell hyperplasia

cell diseases mast

congenital cutaneous mastocytosis

mast cell disease

mastocytoses

10.

mastocytosis

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Imatinib Mesylate	FAERS: 6		US FAERS
2	Lisinopril	FAERS: 3		US FAERS
3	midostaurin	FAERS: 3		US FAERS
4	NuvaRing	FAERS: 2		US FAERS
5	Ranitidine	FAERS: 2		US FAERS
6	Ranitidine	FAERS: 2		US FAERS
7	Teriparatide	FAERS: 2		US FAERS
8	Zoledronic Acid	FAERS: 2		US FAERS
9	4-hydroxybutyric acid	FAERS: 1		US FAERS
10	4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide	FAERS: 1		US FAERS
11	AN2728	FAERS: 1		US FAERS
12	Amlodipine	FAERS: 1		US FAERS
13	Aspirin, Dipyridamole Drug Combination	FAERS: 1		US FAERS
14	Diclofenac	FAERS: 1		US FAERS
15	Esomeprazole	FAERS: 1		US FAERS
16	Gabapentin	FAERS: 1		US FAERS
17	Ibuprofen	FAERS: 1		US FAERS
18	Lorazepam	FAERS: 1		US FAERS
19	Norgestrel	FAERS: 1		US FAERS
20	Pramipexole	FAERS: 1		US FAERS
21	Pregabalin	FAERS: 1		US FAERS
22	Ruxolitinib phosphate	FAERS: 1		US FAERS
23	Sitagliptin Phosphate	FAERS: 1		US FAERS
24	Valproic Acid	FAERS: 1		US FAERS
25	Venlafaxine Hydrochloride	FAERS: 1		US FAERS
26	ecallantide	FAERS: 1		US FAERS
27	fexofenadine	FAERS: 1		US FAERS
28	levocetirizine	FAERS: 1		US FAERS
29	tofacitinib	FAERS: 1		US FAERS
30	Imatinib Mesylate			SIDER
31	Indomethacin		12559315	CTD
32	desloratadine	Canada Vigilance: 1		Canada Vigilance

Similar ADE(s)

	Name	Semantic Similarity
1	Pyoderma Gangrenosum	30.2%
2	Giant Cell Tumor of Bone	29.6%
3	Chondrosarcoma	29.1%
4	synovial sarcoma	29.1%
5	Clear Cell Sarcoma of Soft Tissue	29.1%
6	Dermatitis, Atopic	27.6%
7	Dermatitis, Photoallergic	25.4%
8	Myxoma	25%
9	Neoplasms, Bone Tissue	25%
10	Neoplasms, Fibrous Tissue	25%
11	Chondroma	25%
12	Enchondroma	25%
13	Dermatitis, Phototoxic	24.7%
14	Pityriasis Lichenoides et Varioliformis Acuta	24.7%
15	Pityriasis Lichenoides	24.7%
16	Phototoxicity	24.7%
17	Serum Sickness	24.5%
18	Acne Vulgaris	24.2%
19	Contact Dermatitis	24.2%
20	Eczema	24.2%
21	Erythema Multiforme	24.2%
22	Intertrigo	24.2%
23	Neurodermatitis	24.2%
24	Rhinophyma	24.2%
25	Perioral Dermatitis	24.2%
26	Acne	24.2%
27	Fibrosarcoma	24.1%
28	Osteosarcoma	24.1%
29	Dermatitis Herpetiformis	23.7%
30	Xeroderma Pigmentosum	23.5%
31	Dermatitis, Allergic Contact	23.2%
32	Epidermolysis Bullosa	22.6%
33	Lupus Erythematosus, Cutaneous	22.1%
34	Panniculitis	22.1%
35	Systemic Scleroderma	22.1%
36	Morphea	22.1%
37	Foot Ulcer	22%
38	Sebaceous Gland Neoplasms	21.8%
39	Malignant Fibrous Histiocytoma	21.6%
40	Panniculitis, Lupus Erythematosus	20.9%
41	Breast Diseases	20.5%
42	Dermatitis	20.5%
43	Exanthema	20.5%
44	Facial Dermatoses	20.5%
45	Hair Diseases	20.5%
46	Hand Dermatoses	20.5%
47	keratoacanthoma	20.5%
48	Keratosis	20.5%
49	Nail Diseases	20.5%
50	Photosensitivity Disorders	20.5%
51	Prurigo	20.5%
52	Pyoderma	20.5%
53	Rosacea	20.5%
54	Sebaceous Gland Diseases	20.5%
55	Skin Diseases, Vesiculobullous	20.5%
56	Skin Ulcer	20.5%
57	Sweat Gland Diseases	20.5%
58	Skin Diseases, Papulosquamous	20.5%
59	Skin Diseases, Vascular	20.5%
60	Acneiform Eruptions	20.5%
61	Ocular Rosacea	20.5%
62	Subcorneal pustular dermatosis	20.5%
63	Erythematotelangiectatic Rosacea	20.5%
64	Papulopustular Rosacea	20.5%
65	Chronic Actinic Dermatitis	20.5%
66	Urticaria	20.1%
67	Acrodermatitis	20.1%
68	Porokeratosis	20.1%
69	Gianotti-Crosti Syndrome	20.1%
70	Keratoderma, Palmoplantar	20.1%
71	Skin Neoplasms	20%
72	Dermatitis, Irritant	19.9%
73	Acne Conglobata	19.9%
74	Erythema Nodosum	19.8%
75	Toxic Epidermal Necrolysis	19.7%
76	Stevens-Johnson Syndrome	19.7%
77	Necrobiosis Lipoidica Diabeticorum	19.5%
78	Dermatofibrosarcoma	19.2%
79	Dermatofibrosarcoma Protuberans	19.2%
80	Vasculitis, Leukocytoclastic, Cutaneous	18.8%
81	fibroma	18.7%
82	Fibromatosis	18.7%
83	Osteoblastoma	18.7%
84	Osteoma	18.7%
85	Chondromatosis	18.7%
86	leiomyosarcoma	18.5%
87	liposarcoma	18.5%
88	Angiomyolipoma	18.5%
89	Alveolar Soft Part Sarcoma	18.5%
90	Erythema Induratum	18.2%
91	Diaper Rash	17.8%
92	Sarcoma	17.6%
93	Xeroderma	17.4%
94	Dermatitis, Occupational	17.1%
95	Foot Diseases	17%
96	Drug Eruptions	16.8%
97	Gastrointestinal Stromal Tumors	16.7%
98	Skin Abnormalities	16.6%
99	Skin Diseases, Infectious	16.6%
100	Pigmentation Disorders	16.6%
101	Papillon-Lefevre Disease	16.5%
102	Lipomatosis	16.3%
103	Pemphigus	16.3%
104	Pruritus	16.3%
105	Erythema	16.3%
106	Necrolytic Migratory Erythema	16.3%
107	Cutaneous Fistula	16.3%
108	Nephrogenic Fibrosing Dermopathy	16.3%
109	Nephrogenic Systemic Fibrosis	16.3%
110	Adenofibroma	16.3%
111	Fibroadenoma	16.3%
112	Lupus Erythematosus, Discoid	16.1%
113	Scleroderma, Limited	16.1%
114	Erythema Infectiosum	15.9%
115	Exanthema Subitum	15.8%
116	Breast Cyst	15.6%
117	Actinic keratosis	15.6%
118	Fibromatosis, Aggressive	15.5%
119	Fibromatosis, Abdominal	15.5%
120	Dermatomyositis	15.4%
121	Latex allergy	15.4%
122	Carcinosarcoma	15.3%
123	Hemangiosarcoma	15.3%
124	lymphangiosarcoma	15.3%
125	Hyperkeratosis, Epidermolytic	15.2%
126	Anhidrosis	15.1%
127	Cholesteatoma	15.1%
128	Pressure Ulcer	15.1%
129	Folliculitis	15.1%
130	Foot Dermatoses	15.1%
131	Gynecomastia	15.1%
132	Hypertrichosis	15.1%
133	Hypohidrosis	15.1%
134	Hypotrichosis	15.1%
135	Leg Ulcer	15.1%
136	Miliaria	15.1%
137	Parakeratosis	15.1%
138	Parapsoriasis	15.1%
139	Pityriasis	15.1%
140	Psoriasis	15.1%
141	Sweet Syndrome	15.1%
142	Hidradenitis	15.1%
143	Onycholysis	15.1%
144	Miliaria Rubra	15.1%
145	Hyperpigmentation	15.1%
146	Lichenoid Eruptions	15.1%
147	Chloracne	15.1%
148	Ectodermal Dysplasia	15.1%
149	Aplasia Cutis Congenita	15.1%
150	Dupuytren Contracture	15%
151	Tinea Capitis	14.8%
152	Onychomycosis	14.8%
153	Pseudoxanthoma Elasticum	14.8%
154	Cutis Laxa	14.7%
155	Rhabdomyosarcoma	13.8%
156	Neurofibrosarcoma	13.7%
157	Ecthyma	13.6%
158	Carcinoma, Lobular	13.4%
159	Angioedema	13.4%
160	Sarcoma, Myeloid	13.2%
161	Ichthyosis, X-Linked	13.2%
162	Acute Generalized Exanthematous Pustulosis	13.2%
163	Sjogren-Larsson Syndrome	13.1%
164	leukemia	12.8%
165	Neoplasms, Germ Cell and Embryonal	12.8%
166	Neoplasms, Glandular and Epithelial	12.8%
167	Germ Cell Cancer	12.8%
168	Granuloma Annulare	12.8%
169	Environmental Illness	12.8%
170	Lichen Planus	12.5%
171	Melanosis	12.5%
172	Chloasma	12.5%
173	Pityriasis Rosea	12.5%
174	Pityriasis Rubra Pilaris	12.5%
175	Vitiligo	12.5%
176	Lichen Nitidus	12.5%
177	Hidradenitis Suppurativa	12.4%
178	Acantholysis	12.2%
179	Behcet Syndrome	12.2%
180	Pemphigoid, Benign Mucous Membrane	12.2%
181	Piedra	12.2%
182	Sunburn	12.2%
183	Argyria	12.1%
184	Hirsutism	12.1%
185	Lactation Disorder	12.1%
186	Mastitis	12.1%
187	Neuroectodermal Tumors	12.1%
188	Adiposis Dolorosa	12%
189	Pruritus Vulvae	12%
190	Breast Neoplasms, Male	12%
191	Triple Negative Breast Neoplasms	12%
192	Carcinoma 256, Walker	12%
193	Pruritus Ani	12%
194	Phyllodes Tumor	11.7%
195	Lipoma	11.7%
196	Myoma	11.7%
197	Angiolipoma	11.7%
198	Myelolipoma	11.7%
199	Smooth Muscle Tumor	11.7%
200	Desmoplastic Small Round Cell Tumor	11.7%
201	Tinea Pedis	11.6%
202	Neoplasms, Neuroepithelial	11.6%
203	Gliomatosis cerebri	11.6%
204	Alveolar rhabdomyosarcoma	11.5%
205	Acanthosis Nigricans	11.2%
206	Alopecia Areata	11.2%
207	Lentigo	11.2%
208	Albinism	11%
209	Erythema Chronicum Migrans	10.8%
210	Lymphangioleiomyomatosis	10.8%
211	Lymphoma	10.7%
212	Hereditary Angioedema Type III	10.6%
213	Hereditary Angioedema Types I and II	10.6%
214	Connective Tissue Diseases	10.6%
215	Sarcoma, Experimental	10.6%
216	Histiocytic Disorders, Malignant	10.2%
217	Dermatomycoses	10.2%
218	Mucocutaneous Lymph Node Syndrome	10.2%
219	Skin Diseases, Bacterial	10.2%
220	Kounis Syndrome	10.2%
221	Alopecia	10.1%
222	Sweating, Gustatory	10.1%
223	Androgenetic Alopecia	10.1%
224	Auriculotemporal Syndrome	10.1%
225	anaphylaxis	10.1%
226	Food Allergy	10.1%
227	Anaphylactic shock	10.1%
228	Lipodystrophy	10.1%
229	Livedo Reticularis	10.1%
230	Malignant Atrophic Papulosis	10.1%
231	Asthma, Aspirin-Induced	10%
232	Angioedemas, Hereditary	10%
233	Lice Infestations	10%
234	Varicose Ulcer	10%
235	Composite Lymphoma	10%
236	Leukemia, Plasma Cell	9.9%
237	Polyarteritis Nodosa	9.9%
238	Takayasu Arteritis	9.9%
239	Galactorrhea	9.9%
240	Urticaria Pigmentosa	9.9%
241	melanoma	9.9%
242	Mycetoma	9.9%
243	Lupus Erythematosus, Systemic	9.7%
244	Overlap syndrome	9.7%
245	Meningioma	9.2%
246	Endometrial Stromal Sarcoma	9.1%
247	Lichen Planus, Oral	9.1%
248	Sarcoma 180	9%
249	Autoimmune Diseases	8.8%
250	Immunologic Deficiency Syndromes	8.8%
251	Immunoproliferative Disorders	8.8%
252	Immune reconstitution syndrome	8.8%
253	Immune Reconstitution Inflammatory Syndrome	8.8%
254	Nail-Patella Syndrome	8.8%
255	Plasmacytoma	8.7%
256	Rhabdomyoma	8.7%
257	Porphyrias, Hepatic	8.7%
258	Medulloblastoma	8.6%
259	Peutz-Jeghers Syndrome	8.5%
260	Larva Migrans	8.4%
261	Leishmaniasis	8.4%
262	Molluscum Contagiosum	8.4%
263	Respiratory Hypersensitivity	8.4%
264	Onchocerciasis	8.3%
265	Chromoblastomycosis	8.3%
266	Dermatophytosis	8.3%
267	Sporotrichosis	8.3%
268	Tinea	8.3%
269	Tinea Versicolor	8.3%
270	Trichophytosis	8.3%
271	Hyalohyphomycosis	8.3%
272	Adenoma, Acidophil	8.2%
273	Ganglioneuroma	8.2%
274	Glioma	8.2%
275	Malignant Glioma	8.2%
276	Sick Building Syndrome	8.2%
277	Multiple Chemical Sensitivity	8.2%
278	Primary amyloidosis	8.1%
279	Hamartoma	8%
280	Neoplasms, Hormone-Dependent	8%
281	Neoplasms, Multiple Primary	8%
282	Paraneoplastic Syndromes	8%
283	Precancerous Conditions	8%
284	Neoplasms, Second Primary	8%
285	Basal cell carcinoma	7.9%
286	Carcinoma, Papillary	7.9%
287	Squamous cell carcinoma	7.9%
288	Craniopharyngioma	7.9%
289	Cystadenoma	7.9%
290	Mesothelioma	7.9%
291	Neuroectodermal Tumor, Melanotic	7.9%
292	Neuroendocrine Tumors	7.9%
293	Carcinoma, Basal Cell	7.9%
294	Trophoblastic Neoplasms	7.9%
295	Leukemia, Experimental	7.9%
296	Melanoma, Experimental	7.6%
297	Adenoma	7.6%
298	Ameloblastoma	7.6%
299	Angiokeratoma	7.6%
300	Carcinoma	7.6%
301	Chordoma	7.6%
302	Hemangioma	7.6%
303	hemangiopericytoma	7.6%
304	Lymphangioma	7.6%
305	Mesenchymoma	7.6%
306	Nevus	7.6%
307	Teratoma	7.6%
308	Hepatoblastoma	7.6%
309	Mixed Tumor, Mullerian	7.6%
310	Germinoma	7.6%
311	Teratocarcinoma	7.6%
312	Angiofibroma	7.6%
313	Epithelioma	7.6%
314	Milk Allergy	7.5%
315	Wheat Hypersensitivity	7.5%
316	Myxoid cyst	7.5%
317	Leishmaniasis, Cutaneous	7.4%
318	Eczema Herpeticum	7.4%
319	Carcinoma, Ehrlich Tumor	7.4%
320	Dermoid Cyst	7.4%
321	Carcinoma, Lewis Lung	7.4%
322	Fusariosis	7.4%
323	Carcinoid Tumor	7.4%
324	Neurilemmoma	7.4%
325	Hutchinson's Melanotic Freckle	7.4%
326	Melanoma, Amelanotic	7.4%
327	CREST Syndrome	7.3%
328	Warts	7.3%
329	Candidiasis, Chronic Mucocutaneous	7.1%
330	Cutaneous Candidiasis	7.1%
331	Transfusion Reaction	7.1%
332	Hypotensive Transfusion Reaction	7.1%
333	Erysipelas	7.1%
334	Staphylococcal Skin Infections	7.1%
335	Variegate Porphyria	7.1%
336	Acute intermittent porphyria	7.1%
337	Porphyria Cutanea Tarda	7.1%
338	Erythrasma	7.1%
339	Arthritis, Psoriatic	7%
340	Cystadenocarcinoma	6.9%
341	Mucoepidermoid Carcinoma	6.9%
342	HIV-Associated Lipodystrophy Syndrome	6.9%
343	Giant Cell Arteritis	6.9%
344	Temporal Arteritis	6.9%
345	Collagen Diseases	6.8%
346	Mixed Connective Tissue Disease	6.8%
347	Mucinoses	6.8%
348	Leukemia, Radiation-Induced	6.8%
349	Hodgkin Disease	6.6%
350	Lymphoma, Non-Hodgkin	6.6%
351	Astrocytoma	6.5%
352	Ependymoma	6.5%
353	oligodendroglioma	6.5%
354	Ganglioglioma	6.5%
355	gliosarcoma	6.5%
356	Anaplastic astrocytoma	6.5%
357	Anaplastic Oligodendroglioma	6.5%
358	Cyst	6.4%
359	Epidermodysplasia Verruciformis	6.4%
360	Herpes Labialis	6.4%
361	Neoplastic Processes	6.4%
362	Neoplastic Syndromes, Hereditary	6.4%
363	Pregnancy Complications, Neoplastic	6.4%
364	Choriocarcinoma	6.4%
365	Diabetic Foot	6.4%
366	Neoplasms, Experimental	6.3%
367	Staphylococcal Scalded Skin Syndrome	6.3%
368	Multiple Myeloma	6.3%
369	Thymoma	6.1%
370	Malignant Carcinoid Syndrome	6.1%
371	Malignant histiocytosis	6%
372	Leukemia L1210	6%
373	Leukemia P388	6%
374	Histiocytic sarcoma	6%
375	Acanthoma	6%
376	Bowen's Disease	5.9%
377	Paraganglioma	5.9%
378	carbuncle	5.9%
379	Rheumatoid Arthritis	5.9%
380	Juvenile arthritis	5.9%
381	Glioblastoma	5.7%
382	Neuroblastoma	5.7%
383	Glioblastoma Multiforme	5.7%
384	Cartilage Diseases	5.7%
385	Glomerulonephritis, Membranoproliferative	5.7%
386	Rheumatism	5.7%
387	Chondromalacia	5.7%
388	Retinoblastoma	5.6%
389	Condylomata Acuminata	5.6%
390	Multiple Endocrine Neoplasia	5.6%
391	Furunculosis	5.6%
392	furuncle	5.6%
393	Lymphomatoid Granulomatosis	5.5%
394	Blastomycosis	5.5%
395	Impetigo	5.5%
396	Ganglioneuroblastoma	5.3%
397	Neoplasms, Radiation-Induced	5.2%
398	Antiphospholipid Syndrome	5.1%
399	Rhinoscleroma	5.1%
400	Scleromyxedema	5%
401	Adenocarcinoma	5%
402	Carcinoma in Situ	5%
403	Carcinoma, Transitional Cell	5%
404	Dysgerminoma	5%
405	Hemangioendothelioma	5%
406	Neuroma	5%
407	Papilloma	5%
408	Pseudomyxoma Peritonei	5%
409	Seminoma	5%
410	Papillomatosis	5%
411	Adenomatosis, Pulmonary	5%
412	Adenomatous Polyps	5%
413	Carcinoma, Large Cell	5%
414	Carcinoma, Small Cell	5%
415	Leukemia, T-Cell	4.9%
416	Leukemia, B-Cell	4.9%
417	Pheochromocytoma	4.9%
418	Autoimmune Lymphoproliferative Syndrome	4.9%
419	Waldenstrom Macroglobulinemia	4.8%
420	Carcinoid Heart Disease	4.8%
421	Lupus Nephritis	4.7%
422	Nephroblastoma	4.6%
423	Lymphoma, Follicular	4.6%
424	T-Cell Lymphoma	4.6%
425	Mantle cell lymphoma	4.6%
426	Paraneoplastic Encephalomyelitis	4.6%
427	Menkes Kinky Hair Syndrome	4.5%
428	Mammary Neoplasms, Experimental	4.5%
429	Asthma	4.4%
430	Abdominal Neoplasms	4.3%
431	Erythroplasia	4.3%
432	Follicular cyst	4.3%
433	Head and Neck Neoplasms	4.3%
434	Mucocele	4.3%
435	Pilonidal Cyst	4.3%
436	Soft Tissue Neoplasms	4.3%
437	Thoracic Neoplasms	4.3%
438	Thyroglossal Cyst	4.3%
439	Synovial Cyst	4.3%
440	Aberrant Crypt Foci	4.3%
441	Felty Syndrome	4.3%
442	Basal Cell Nevus Syndrome	4.3%
443	Tuberous Sclerosis	4.2%
444	Thrombocytopenic purpura	4.2%
445	Asthma, Exercise-Induced	4.2%
446	Status Asthmaticus	4.2%
447	Lymphoproliferative Disorders	4.1%
448	Addison Disease	4.1%
449	Mesenteric Panniculitis	4.1%
450	Panniculitis, Peritoneal	4.1%
451	Paraproteinemias	4.1%
452	Tietze's Syndrome	4.1%
453	Orbital Cellulitis	4.1%
454	Autoimmune thyroiditis	4.1%
455	Primary Adrenal Insufficiency	4.1%
456	Lymphopenia	4.1%
457	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	4.1%
458	Autoimmune hepatitis	4.1%
459	Sezary Syndrome	4%
460	Acoustic Neuroma	4%
461	Myxedema	4%
462	Carcinoma, Pancreatic Ductal	4%
463	Autoimmune thrombocytopenia	4%
464	Immune thrombocytopenic purpura	4%
465	Leukemia, Myelomonocytic, Chronic	4%
466	Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative	4%
467	Cellulitis	3.8%
468	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	3.8%
469	Leukemia, Large Granular Lymphocytic	3.8%
470	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	3.8%
471	Mesoblastic Nephroma	3.8%
472	Monoclonal Gammopathy of Undetermined Significance	3.8%
473	Hepatocellular Adenoma	3.8%
474	Aspergillosis, Allergic Bronchopulmonary	3.7%
475	Adenoid Cystic Carcinoma	3.7%
476	Adenocarcinoma, Clear Cell	3.7%
477	Cholangiocarcinoma	3.7%
478	Cervical Intraepithelial Neoplasia	3.7%
479	Hemangioblastoma	3.7%
480	Lymphoma, Extranodal NK-T-Cell	3.7%
481	Rheumatoid Vasculitis	3.7%
482	Optic Nerve Glioma	3.7%
483	Lymphoma, T-Cell, Cutaneous	3.7%
484	Lymphoma, AIDS-Related	3.7%
485	Enteropathy-Associated T-Cell Lymphoma	3.7%
486	Primary Effusion Lymphoma	3.7%
487	Asthma, Occupational	3.7%
488	Farmer's Lung	3.6%
489	Hydatidiform Mole	3.6%
490	Digestive System Neoplasms	3.5%
491	Endocrine Gland Neoplasms	3.5%
492	Eye Neoplasms	3.5%
493	Nervous System Neoplasms	3.5%
494	Hay fever	3.5%
495	Rhinitis, Allergic, Perennial	3.5%
496	Bone neoplasms	3.4%
497	Leukoplakia	3.4%
498	Lymphocele	3.4%
499	Pancreatic Cyst	3.4%
500	Hematologic Neoplasms	3.4%
501	Hypergammaglobulinemia	3.4%
502	Osteochondritis	3.4%
503	Polymyalgia Rheumatica	3.4%
504	Latent Autoimmune Diabetes in Adults	3.4%
505	Vipoma	3.4%
506	Barrett Esophagus	3.4%
507	Mediastinal Cyst	3.4%
508	Neoplasm Invasiveness	3.4%
509	Neoplasm Metastasis	3.4%
510	Neoplasm Recurrence, Local	3.4%
511	Parovarian Cyst	3.4%
512	Pericardial Cyst	3.4%
513	Splenic Neoplasms	3.4%
514	Thymic Cyst	3.4%
515	Carcinogenesis	3.4%
516	Metastasis	3.4%
517	Agammaglobulinemia	3.4%
518	HIV Infections	3.4%
519	Osteogenesis Imperfecta	3.4%
520	Sturge-Weber Syndrome	3.4%
521	Transfusion-Related Acute Lung Injury	3.4%
522	Lambert-Eaton Myasthenic Syndrome	3.4%
523	Multiple Endocrine Neoplasia Type 1	3.3%
524	Hemangioma, Cavernous	3.3%
525	Keloid	3.3%
526	Sicca Syndrome	3.3%
527	Sjogren's Syndrome	3.3%
528	Prolactinoma	3.3%
529	Growth Hormone-Secreting Pituitary Adenoma	3.3%
530	neurofibroma	3.3%
531	Mycosis Fungoides	3.2%
532	Lymphomatoid Papulosis	3.2%
533	Plasmablastic lymphoma	3.2%
534	Klatskin Tumor	3.1%
535	Lupus Vasculitis, Central Nervous System	3%
536	Noonan Syndrome	3%
537	Leukemia, Myeloid, Chronic-Phase	3%
538	Liver Neoplasms, Experimental	2.9%
539	Adenomatous Polyposis Coli	2.9%
540	Parathyroid Neoplasms	2.9%
541	Peritoneal Neoplasms	2.9%
542	Thyroid Neoplasm	2.9%
543	Thyroid carcinoma	2.9%
544	granulosa cell tumor	2.9%
545	Carcinoma, Ovarian Epithelial	2.9%
546	Graves Disease	2.9%
547	Anti-Glomerular Basement Membrane Disease	2.9%
548	Corpus Luteum Cyst	2.8%
549	Ovarian Cysts	2.8%
550	Rheumatoid Nodule	2.8%
551	Burkitt Lymphoma	2.8%
552	insulinoma	2.7%
553	Marfan Syndrome	2.7%
554	Tumor Lysis Syndrome	2.7%
555	HTLV-I Infections	2.7%
556	Job Syndrome	2.7%
557	Homocystinuria	2.6%
558	Pancreatic Neoplasm	2.6%
559	Laryngomalacia	2.6%
560	Pectus carinatum	2.6%
561	Retroperitoneal Neoplasms	2.5%
562	Schnitzler Syndrome	2.5%
563	Adrenocortical carcinoma	2.4%
564	Choledochal Cyst	2.4%
565	Gastrinoma	2.4%
566	Glucagonoma	2.4%
567	Tracheal Neoplasms	2.4%
568	Myelitis, Transverse	2.4%
569	Leukoplakia, Oral	2.4%
570	Bronchomalacia	2.4%
571	Paraneoplastic Cerebellar Degeneration	2.4%
572	Tracheomalacia	2.4%
573	Nasopharyngeal carcinoma	2.4%
574	Leydig Cell Tumor	2.3%
575	Myasthenia Gravis	2.3%
576	Uveomeningoencephalitic Syndrome	2.3%
577	Kernicterus	2.2%
578	Chronic granulomatous disease	2.2%
579	Heavy Chain Disease	2.2%
580	Granulomatosis with polyangiitis	2.2%
581	Denys-Drash Syndrome	2.2%
582	HIV Seropositivity	2.2%
583	Myasthenia Gravis, Autoimmune, Experimental	2.2%
584	Renal Cell Carcinoma	2.2%
585	Papillary Renal Cell Carcinoma	2.2%
586	Esophageal Neoplasms	2.1%
587	Carcinoma, Endometrioid	2.1%
588	Limbic Encephalitis	2.1%
589	Mouth Neoplasms	2%
590	Central Nervous System Neoplasms	2%
591	Vascular Neoplasms	2%
592	Thymus Neoplasms	2%
593	Mucopolysaccharidosis III	2%
594	Ataxia Telangiectasia	2%
595	Genital Neoplasms, Female	2%
596	Pancreatic Pseudocyst	2%
597	Lymphatic Metastasis	2%
598	Neoplasms, Unknown Primary	2%
599	Leukemic Infiltration	2%
600	Neoplasm Micrometastasis	2%
601	Hydrops Fetalis	2%
602	Stiff-Person Syndrome	2%
603	Polyradiculoneuropathy	1.9%
604	Polyradiculoneuritis	1.9%
605	Acquired Immunodeficiency Syndrome	1.9%
606	AIDS related complex	1.9%
607	Infectious Mononucleosis	1.9%
608	Cryoglobulinemia	1.9%
609	Thyroid Nodule	1.9%
610	POEMS Syndrome	1.9%
611	Testicular Neoplasms	1.9%
612	Adrenal Gland Neoplasms	1.7%
613	Gastrointestinal Neoplasms	1.7%
614	Genital Neoplasms, Male	1.7%
615	Liver neoplasms	1.7%
616	Uveal Neoplasms	1.7%
617	Urologic Neoplasms	1.7%
618	AIDS-Related Opportunistic Infections	1.7%
619	Vasculitis, Central Nervous System	1.7%
620	Spinal Neoplasms	1.7%
621	Bone Marrow Neoplasms	1.7%
622	Opsoclonus-Myoclonus Syndrome	1.7%
623	Multiple Sclerosis	1.7%
624	HIV Wasting Syndrome	1.7%
625	Polycystic Ovary Syndrome	1.7%
626	AIDS Dementia Complex	1.6%
627	AIDS-Associated Nephropathy	1.6%
628	Neuromyelitis Optica	1.6%
629	Leukoencephalitis, Acute Hemorrhagic	1.6%
630	Wiskott-Aldrich Syndrome	1.5%
631	Mucopolysaccharidosis II	1.5%
632	Encephalomyelitis, Acute Disseminated	1.4%
633	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	1.4%
634	Neuritis, Autoimmune, Experimental	1.4%
635	Multiple Sclerosis, Chronic Progressive	1.4%
636	Multiple Sclerosis, Relapsing-Remitting	1.4%
637	Nose Neoplasms	1.4%
638	Meningeal Neoplasms	1.3%
639	Palatal Neoplasms	1.3%
640	ovarian neoplasm	1.3%
641	Guillain-Barre Syndrome	1.2%
642	Pituitary Adenoma	1.2%
643	Pituitary Neoplasms	1.2%
644	Ear Neoplasms	1.1%
645	Eyelid Neoplasms	1.1%
646	Lung Neoplasms	1.1%
647	Pleural Neoplasms	1.1%
648	Cell Transformation, Viral	1.1%
649	Brain Neoplasms	1.1%
650	Salivary Gland Neoplasms	1.1%
651	Spinal Cord Neoplasms	1.1%
652	Tongue Neoplasms	1.1%
653	Uterine Neoplasms	1.1%
654	Vaginal Neoplasms	1.1%
655	Vulvar Neoplasms	1.1%
656	Uterine Cancer	1.1%
657	Fallopian Tube Neoplasms	1.1%
658	Zollinger-Ellison syndrome	1%
659	Meningeal Carcinomatosis	1%
660	Pharyngeal Neoplasms	1%
661	Central Nervous System Cysts	1%
662	Bile Duct Neoplasms	1%
663	gallbladder neoplasm	1%
664	Intestinal Neoplasms	1%
665	Penile Neoplasms	1%
666	Prostatic Neoplasms	1%
667	Stomach Neoplasms	1%
668	Polycythemia Vera	0.9%
669	Laryngeal neoplasm	0.9%
670	Bronchial Neoplasms	0.8%
671	Multiple Pulmonary Nodules	0.8%
672	Bladder Neoplasm	0.8%
673	Kidney Neoplasm	0.8%
674	Ureteral Neoplasms	0.8%
675	Urethral Neoplasms	0.8%
676	Supratentorial Neoplasms	0.8%
677	Endometrial Neoplasms	0.8%
678	Miller Fisher Syndrome	0.7%
679	Hypopharyngeal Neoplasms	0.7%
680	Pleural Effusion, Malignant	0.7%
681	Hypopharyngeal Cancer	0.7%
682	Parotid Neoplasms	0.7%
683	Prostatic Neoplasms, Castration-Resistant	0.7%
684	Nelson Syndrome	0.7%
685	Brain Stem Neoplasms	0.7%
686	Cecal Neoplasms	0.6%
687	Duodenal Neoplasms	0.6%
688	Choroid Plexus Papilloma	0.6%
689	Tonsillar Neoplasms	0.6%
690	Cerebellar Neoplasms	0.6%
691	Nasopharyngeal Neoplasms	0.6%
692	Colorectal Neoplasms	0.5%
693	Radicular Cyst	0.5%
694	Appendiceal Neoplasms	0.5%
695	Colonic Neoplasms	0.5%
696	Rectal Neoplasms	0.5%
697	Paranasal Sinus Neoplasms	0.5%
698	Maxillary Sinus Neoplasms	0.4%
699	Anus Neoplasms	0.4%
700	Sigmoid Neoplasms	0.4%

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