MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Hypotrichosis

(UMLS:C0020678)

Definition:: Presence of less than the normal amount of hair. (Dorland, 27th ed)
UMLS ID:: C0020678
MeSH ID:: D007039

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.329.937

Synonym(s)

Hypotrichosis

Hair scanty

Hair thin

Hair thinning

Hypotrichosis, NOS

hypotrichosis

sparse hair

the hair was sparse

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Finasteride	FAERS: 15		US FAERS
2	Isotretinoin	FAERS: 10		US FAERS
3	2-(Tert-butylamino)-1-(3-chlorophenyl)propan-1-one;hydron;chloride	FAERS: 9		US FAERS
4	Sorafenib	FAERS: 7		US FAERS
5	Paroxetine	FAERS: 6		US FAERS
6	Teriparatide	FAERS: 6		US FAERS
7	Atomoxetine Hydrochloride	FAERS: 5		US FAERS
8	Erlotinib Hydrochloride	FAERS: 5		US FAERS
9	Exenatide	FAERS: 5		US FAERS
10	Lamotrigine	FAERS: 5		US FAERS
11	MDV 3100	FAERS: 5		US FAERS
12	Valsartan	FAERS: 5		US FAERS
13	tegaserod	FAERS: 5		US FAERS
14	Bimatoprost	FAERS: 4		US FAERS
15	Gabapentin	FAERS: 4		US FAERS
16	Letrozole	FAERS: 4		US FAERS
17	Ortho Evra	FAERS: 4		US FAERS
18	Rosuvastatin Calcium	FAERS: 4		US FAERS
19	Allopurinol	FAERS: 3		US FAERS
20	Carbamazepine	FAERS: 3		US FAERS
21	Gefitinib	FAERS: 3		US FAERS
22	Methylphenidate	FAERS: 3		US FAERS
23	Warfarin	FAERS: 3		US FAERS
24	gemcitabine	FAERS: 3		US FAERS
25	Anastrozole	FAERS: 2		US FAERS
26	Carvedilol	FAERS: 2		US FAERS
27	Ciprofloxacin	FAERS: 2		US FAERS
28	Citalopram	FAERS: 2		US FAERS
29	Duloxetine Hydrochloride	FAERS: 2		US FAERS
30	Estradiol	FAERS: 2		US FAERS
31	Eszopiclone	FAERS: 2		US FAERS
32	Ibandronic Acid	FAERS: 2		US FAERS
33	Medroxyprogesterone Acetate	FAERS: 2		US FAERS
34	Solifenacin Succinate	FAERS: 2		US FAERS
35	Zoledronic Acid	FAERS: 2		US FAERS
36	apalutamide	FAERS: 2		US FAERS
37	etonogestrel	FAERS: 2		US FAERS
38	pazopanib	FAERS: 2		US FAERS
39	Acitretin	FAERS: 1		US FAERS
40	Afatinib	FAERS: 1		US FAERS
41	Amiodarone	FAERS: 1		US FAERS
42	Atorvastatin	FAERS: 1		US FAERS
43	Capecitabine	FAERS: 1		US FAERS
44	Citalopram	FAERS: 1		US FAERS
45	Deoxycholic Acid	FAERS: 1		US FAERS
46	Diltiazem	FAERS: 1		US FAERS
47	Eflornithine	FAERS: 1		US FAERS
48	Ezetimibe	FAERS: 1		US FAERS
49	Fluoxetine	FAERS: 1		US FAERS
50	HhAntag691	FAERS: 1 Canada Vigilance: 1		Canada Vigilance US FAERS
51	Metformin	FAERS: 1		US FAERS
52	Minoxidil	FAERS: 1		US FAERS
53	Mirtazapine	FAERS: 1		US FAERS
54	Mitotane	FAERS: 1		US FAERS
55	Nicotine	FAERS: 1		US FAERS
56	Norgestrel	FAERS: 1	View details 7793168 7847530 7853277 11535212	CTD US FAERS
57	NuvaRing	FAERS: 1		US FAERS
58	Olmesartan Medoxomil	FAERS: 1		US FAERS
59	Prednisone	FAERS: 1		US FAERS
60	Ribavirin	FAERS: 1		US FAERS
61	Risperidone	FAERS: 1		US FAERS
62	Simvastatin	FAERS: 1		US FAERS
63	Sotalol	FAERS: 1		US FAERS
64	Tamoxifen	FAERS: 1		US FAERS
65	Testosterone	FAERS: 1		US FAERS
66	Thyroxine	FAERS: 1		US FAERS
67	Valacyclovir	FAERS: 1		US FAERS
68	Voriconazole	FAERS: 1		US FAERS
69	alfuzosin	FAERS: 1		US FAERS
70	apremilast	FAERS: 1		US FAERS
71	benzoylecgonine	FAERS: 1		US FAERS
72	bicalutamide	FAERS: 1		US FAERS
73	norgestimate, ethinyl estradiol drug combination	FAERS: 1		US FAERS
74	sofosbuvir-velpatasvir drug combination	FAERS: 1		US FAERS
75	telithromycin	FAERS: 1		US FAERS
76	teriflunomide	FAERS: 1		US FAERS
77	testosterone 17 beta-cypionate	FAERS: 1		US FAERS
78	Bupropion			SIDER
79	Colchicine		17505274	CTD
80	Cyproterone Acetate		10660647	CTD
81	Famotidine			SIDER
82	Glyburide			SIDER
83	Imatinib Mesylate			SIDER
84	Methotrexate		5761810	CTD
85	Paclitaxel			SIDER
86	Tacrolimus			SIDER
87	Vitamin A		6071832	CTD
88	histrelin			SIDER
89	lanreotide			SIDER
90	vinflunine			SIDER

Similar ADE(s)

	Name	Semantic Similarity
1	Folliculitis	46.7%
2	Hypertrichosis	46.7%
3	Piedra	31.8%
4	Hirsutism	31.1%
5	Breast Diseases	31%
6	Dermatitis	31%
7	Exanthema	31%
8	Facial Dermatoses	31%
9	Hand Dermatoses	31%
10	keratoacanthoma	31%
11	Keratosis	31%
12	Nail Diseases	31%
13	Photosensitivity Disorders	31%
14	Prurigo	31%
15	Pyoderma	31%
16	Rosacea	31%
17	Sebaceous Gland Diseases	31%
18	Skin Diseases, Vesiculobullous	31%
19	Skin Ulcer	31%
20	Sweat Gland Diseases	31%
21	Skin Diseases, Papulosquamous	31%
22	Skin Diseases, Vascular	31%
23	Acneiform Eruptions	31%
24	Ocular Rosacea	31%
25	Subcorneal pustular dermatosis	31%
26	Erythematotelangiectatic Rosacea	31%
27	Papulopustular Rosacea	31%
28	Chronic Actinic Dermatitis	31%
29	Pyoderma Gangrenosum	30%
30	Lupus Erythematosus, Cutaneous	27.9%
31	Panniculitis	27.9%
32	Systemic Scleroderma	27.9%
33	Morphea	27.9%
34	Acne Vulgaris	26.7%
35	Contact Dermatitis	26.7%
36	Eczema	26.7%
37	Erythema Multiforme	26.7%
38	Intertrigo	26.7%
39	Neurodermatitis	26.7%
40	Rhinophyma	26.7%
41	Perioral Dermatitis	26.7%
42	Acne	26.7%
43	Foot Ulcer	23.1%
44	Foot Diseases	22%
45	Dermatitis, Phototoxic	22%
46	Pityriasis Lichenoides et Varioliformis Acuta	22%
47	Pityriasis Lichenoides	22%
48	Phototoxicity	22%
49	Skin Abnormalities	20.9%
50	Skin Diseases, Infectious	20.9%
51	Skin Neoplasms	20.9%
52	Pigmentation Disorders	20.9%
53	Lipomatosis	20.5%
54	Pruritus	20.5%
55	Erythema	20.5%
56	Necrolytic Migratory Erythema	20.5%
57	Cutaneous Fistula	20.5%
58	Nephrogenic Fibrosing Dermopathy	20.5%
59	Nephrogenic Systemic Fibrosis	20.5%
60	Dermatitis Herpetiformis	20.3%
61	Acrodermatitis	20%
62	Anhidrosis	20%
63	Cholesteatoma	20%
64	Pressure Ulcer	20%
65	Dermatitis, Atopic	20%
66	Epidermolysis Bullosa	20%
67	Foot Dermatoses	20%
68	Gynecomastia	20%
69	Hypohidrosis	20%
70	Leg Ulcer	20%
71	Miliaria	20%
72	Parakeratosis	20%
73	Parapsoriasis	20%
74	Pityriasis	20%
75	Psoriasis	20%
76	Sebaceous Gland Neoplasms	20%
77	Sweet Syndrome	20%
78	Hidradenitis	20%
79	Onycholysis	20%
80	Miliaria Rubra	20%
81	Hyperpigmentation	20%
82	Porokeratosis	20%
83	Lichenoid Eruptions	20%
84	Gianotti-Crosti Syndrome	20%
85	Chloracne	20%
86	Keratoderma, Palmoplantar	20%
87	Dermatitis, Irritant	19.6%
88	Acne Conglobata	19.6%
89	Connective Tissue Diseases	18.5%
90	Panniculitis, Lupus Erythematosus	18.4%
91	Xeroderma Pigmentosum	17.9%
92	Necrobiosis Lipoidica Diabeticorum	17.9%
93	Lupus Erythematosus, Discoid	17.8%
94	Scleroderma, Limited	17.8%
95	Dermatitis, Photoallergic	17.5%
96	Urticaria Pigmentosa	17.1%
97	Xeroderma	16.2%
98	Dermatomyositis	16.2%
99	Diaper Rash	16.1%
100	Dermatitis, Occupational	15.5%
101	Cutis Laxa	15.3%
102	Mastocytosis	15.1%
103	Lichen Planus	14.8%
104	Melanosis	14.8%
105	Chloasma	14.8%
106	Pityriasis Rosea	14.8%
107	Pityriasis Rubra Pilaris	14.8%
108	Vitiligo	14.8%
109	Dermatitis, Allergic Contact	14.8%
110	Lichen Nitidus	14.8%
111	Papillon-Lefevre Disease	14.6%
112	Erythema Induratum	14.4%
113	Erythema Infectiosum	14.1%
114	Exanthema Subitum	14%
115	Erythema Nodosum	13.7%
116	Acantholysis	13.6%
117	Breast Cyst	13.6%
118	Actinic keratosis	13.6%
119	Pemphigoid, Benign Mucous Membrane	13.6%
120	Pemphigus	13.6%
121	Sunburn	13.6%
122	Argyria	13.3%
123	Ectodermal Dysplasia	13.3%
124	Lactation Disorder	13.3%
125	Mastitis	13.3%
126	Urticaria	13.3%
127	Aplasia Cutis Congenita	13.3%
128	Adiposis Dolorosa	13.2%
129	Pruritus Vulvae	13.2%
130	Mastocytoma	13.1%
131	Pruritus Ani	13.1%
132	Tinea Capitis	12.7%
133	Onychomycosis	12.7%
134	Toxic Epidermal Necrolysis	12.6%
135	Stevens-Johnson Syndrome	12.6%
136	Pseudoxanthoma Elasticum	12.6%
137	Granuloma Annulare	12.4%
138	Acanthosis Nigricans	12.2%
139	Lentigo	12.2%
140	Ecthyma	11.5%
141	Hyperkeratosis, Epidermolytic	11%
142	Collagen Diseases	10.3%
143	Mixed Connective Tissue Disease	10.3%
144	Mucinoses	10.3%
145	Dermatomycoses	10.2%
146	Mucocutaneous Lymph Node Syndrome	10.2%
147	Skin Diseases, Bacterial	10.2%
148	Sweating, Gustatory	10.1%
149	Auriculotemporal Syndrome	10.1%
150	Drug Eruptions	10%
151	Lipodystrophy	10%
152	Livedo Reticularis	10%
153	Malignant Atrophic Papulosis	10%
154	Behcet Syndrome	10%
155	Lice Infestations	9.9%
156	Varicose Ulcer	9.9%
157	Breast Neoplasms, Male	9.9%
158	Triple Negative Breast Neoplasms	9.9%
159	Polyarteritis Nodosa	9.8%
160	Takayasu Arteritis	9.8%
161	Ichthyosis, X-Linked	9.8%
162	Hidradenitis Suppurativa	9.8%
163	Galactorrhea	9.8%
164	Sjogren-Larsson Syndrome	9.8%
165	Tinea Pedis	8.9%
166	Albinism	8.7%
167	Erythema Chronicum Migrans	8.5%
168	Lichen Planus, Oral	8.4%
169	Menkes Kinky Hair Syndrome	8.2%
170	Nail-Patella Syndrome	8.2%
171	Porphyrias, Hepatic	8.1%
172	Larva Migrans	7.6%
173	Leishmaniasis	7.6%
174	Molluscum Contagiosum	7.6%
175	Angioedema	7.5%
176	Onchocerciasis	7.5%
177	Chromoblastomycosis	7.4%
178	Dermatophytosis	7.4%
179	Sporotrichosis	7.4%
180	Tinea	7.4%
181	Tinea Versicolor	7.4%
182	Trichophytosis	7.4%
183	Hyalohyphomycosis	7.4%
184	Mycetoma	7.3%
185	Cartilage Diseases	7.3%
186	Rheumatism	7.3%
187	Chondromalacia	7.3%
188	Acute Generalized Exanthematous Pustulosis	7.3%
189	Lupus Erythematosus, Systemic	7%
190	Overlap syndrome	7%
191	Scleromyxedema	6.7%
192	Leishmaniasis, Cutaneous	6.1%
193	Eczema Herpeticum	6.1%
194	Warts	6.1%
195	Fusariosis	6%
196	Candidiasis, Chronic Mucocutaneous	5.9%
197	Cutaneous Candidiasis	5.9%
198	Erysipelas	5.9%
199	Serum Sickness	5.9%
200	Staphylococcal Skin Infections	5.9%
201	Variegate Porphyria	5.9%
202	Acute intermittent porphyria	5.9%
203	Porphyria Cutanea Tarda	5.9%
204	Erythrasma	5.9%
205	Carcinoma, Lobular	5.9%
206	Arthritis, Psoriatic	5.8%
207	CREST Syndrome	5.6%
208	Hereditary Angioedema Type III	5.4%
209	Hereditary Angioedema Types I and II	5.4%
210	Dupuytren Contracture	5%
211	Angioedemas, Hereditary	5%
212	Epidermodysplasia Verruciformis	4.9%
213	Herpes Labialis	4.9%
214	Giant Cell Arteritis	4.9%
215	Temporal Arteritis	4.9%
216	Diabetic Foot	4.9%
217	Staphylococcal Scalded Skin Syndrome	4.8%
218	Mesenteric Panniculitis	4.5%
219	Panniculitis, Peritoneal	4.5%
220	Tietze's Syndrome	4.5%
221	Orbital Cellulitis	4.5%
222	Myxoid cyst	4.5%
223	Peutz-Jeghers Syndrome	4.5%
224	Myxedema	4.4%
225	carbuncle	4.3%
226	Blastomycosis	4.2%
227	HIV-Associated Lipodystrophy Syndrome	4.2%
228	Condylomata Acuminata	4.1%
229	Furunculosis	4.1%
230	furuncle	4.1%
231	Cellulitis	4%
232	Impetigo	4%
233	Rhinoscleroma	3.8%
234	Osteochondritis	3.4%
235	Polymyalgia Rheumatica	3.4%
236	Osteogenesis Imperfecta	3.4%
237	Keloid	3.3%
238	Noonan Syndrome	2.9%
239	Rheumatoid Arthritis	2.7%
240	Juvenile arthritis	2.7%
241	Lupus Nephritis	2.6%
242	Marfan Syndrome	2.5%
243	Rheumatoid Nodule	2.5%
244	Homocystinuria	2.4%
245	Laryngomalacia	2.3%
246	Pectus carinatum	2.3%
247	Felty Syndrome	2%
248	Bronchomalacia	2%
249	Tracheomalacia	2%
250	Rheumatoid Vasculitis	1.6%
251	Mucopolysaccharidosis III	1.6%
252	Sicca Syndrome	1.4%
253	Sjogren's Syndrome	1.4%
254	Lupus Vasculitis, Central Nervous System	1.1%
255	Mucopolysaccharidosis II	1.1%

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