MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Leukoencephalitis, Acute Hemorrhagic

(UMLS:C0014077)

Definition:: A fulminant and often fatal demyelinating disease of the brain which primarily affects young adults and children. Clinical features include the rapid onset of weakness, SEIZURES, and COMA. It may follow a viral illness or MYCOPLASMA PNEUMONIAE infections but in most instances there is no precipitating event. Pathologic examination reveals marked perivascular demyelination and necrosis of white matter with microhemorrhages. (Adams et al., Principles of Neurology, 6th ed, pp924-5)
UMLS ID:: C0014077
MeSH ID:: D004684

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.114.375.225.500|C10.114.375.362|C10.228.140.695.562.225.500|C10.228.140.695.562.375|C10.314.350.225.500|C10.314.350.375

Classification 2:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.111.258.250.350.500|C20.111.258.250.425

Synonym(s)

Leukoencephalitis, Acute Hemorrhagic

ACUTE HEMORRHAGIC LEUKOENCEPHALITIS

Acute Hemorrhagic Leukoencephalitis

Acute haemorrhagic leucoencephalitis

Acute haemorrhagic leukoencephalitis

Acute hemorrhagic encephalomyelitis

Acute hemorrhagic leucoencephalitis

Acute hemorrhagic leukoencephalitis

Acute hemorrhagic leukoencephalitis of Weston Hurst

10.

Hurst syndrome

11.

Hurst's disease

12.

LEUKOENCEPHALITIS, HEMORRHAGIC, ACUTE

13.

ear-patella-short stature (EPS) syndrome

14.

hurst disease

15.

hurst's disease

16.

microtia-absent patellae-micrognathia syndrome

Associated Drug(s)

	Name	Number of Reports	Reference(s)	Data Source
1	Maloprim		17907889	CTD
2	Sulfadiazine		17907889	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Neuromyelitis Optica	62.8%
2	Multiple Sclerosis	51.4%
3	Myelitis, Transverse	46.6%
4	Leukoencephalitis, Acute Hemorrhagic	46.3%
5	Polyradiculoneuropathy	43%
6	Polyradiculoneuritis	43%
7	Stiff-Person Syndrome	41.3%
8	Encephalomyelitis, Acute Disseminated	40.1%
9	Multiple Sclerosis, Chronic Progressive	36%
10	Multiple Sclerosis, Relapsing-Remitting	36%
11	Myasthenia Gravis	32.8%
12	Vasculitis, Central Nervous System	30.4%
13	Lambert-Eaton Myasthenic Syndrome	30.2%
14	Guillain-Barre Syndrome	29.6%
15	Myasthenia Gravis, Autoimmune, Experimental	29.5%
16	Multiple System Atrophy	29.2%
17	Leukoencephalopathy, Progressive Multifocal	28.3%
18	Subacute Combined Degeneration	28.2%
19	Meningoencephalitis	28.1%
20	Lupus Vasculitis, Central Nervous System	27.9%
21	Ophthalmoplegic Migraine	27.2%
22	Uveomeningoencephalitic Syndrome	27.2%
23	Dementia, Vascular	27%
24	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	26.9%
25	Miller Fisher Syndrome	26.8%
26	Marchiafava-Bignami Disease	26.7%
27	Encephalomyelitis	25%
28	Lewy Body Disease	24.7%
29	Pneumocephalus	24.5%
30	Myelinolysis, Central Pontine	24.4%
31	Dandy-Walker Syndrome	24.3%
32	Ocular Motility Disorders	24.1%
33	Cyclophoria	24.1%
34	Posterior Leukoencephalopathy Syndrome	23%
35	Posterior reversible encephalopathy syndrome	23%
36	Progressive supranuclear palsy	22%
37	Restless Legs Syndrome	21.9%
38	Subdural Effusion	21.2%
39	Amyotrophic Lateral Sclerosis	21.2%
40	Brain Abscess	20.6%
41	Canavan Disease	20.5%
42	Alexander Disease	20.5%
43	Parkinson Disease	20.5%
44	Motor Neuron Disease	20.2%
45	Epidural Abscess	20.2%
46	Cranial nerve diseases	20.1%
47	Neuromuscular Diseases	20.1%
48	Chronobiology Disorders	20.1%
49	Huntington Disease	19.6%
50	Brain Injuries	19.5%
51	Brain Neoplasms	19.5%
52	Spinal Muscular Atrophy	19.5%
53	Progressive Muscular Atrophy	19.5%
54	Prion Diseases	19.3%
55	Epilepsy, Post-Traumatic	19.2%
56	Neuritis, Autoimmune, Experimental	18.9%
57	Striatonigral Degeneration	18.9%
58	Parkinsonian Disorders	18.6%
59	Trauma, Nervous System	18.5%
60	Myelitis	18.4%
61	Nervous System Neoplasms	18.3%
62	Neurologic Manifestations	18.3%
63	Neurotoxicity Syndromes	18.3%
64	Poliomyelitis	18.2%
65	Dystonia Musculorum Deformans	17.9%
66	Spinal Cord Injuries	17.9%
67	Neuroleptic Malignant Syndrome	17.8%
68	Asterixis	17.6%
69	Ballismus	17.6%
70	Meningitis	17.5%
71	Movement Disorders	17.5%
72	Pachymeningitis	17.5%
73	Spinal Cord Diseases	17.5%
74	Shy-Drager Syndrome	17.4%
75	Basal Ganglia Cerebrovascular Disease	17.2%
76	Opsoclonus-Myoclonus Syndrome	17.1%
77	Akinetic Mutism	17%
78	Anoxic Encephalopathy	17%
79	Basal Ganglia Diseases	17%
80	Brain Damage, Chronic	17%
81	Cerebellar Diseases	17%
82	Encephalitis	17%
83	Encephalomalacia	17%
84	Epilepsy	17%
85	Hydrocephalus	17%
86	Congenital Hydrocephalus	17%
87	Hypothalamic Diseases	17%
88	Thalamic Diseases	17%
89	Intracranial Hypertension	17%
90	Aura	17%
91	Neuroaxonal Dystrophies	17%
92	Headache Disorders	17%
93	Intracranial Hypotension	17%
94	Brain Edema	17%
95	Brain Hypoxia	17%
96	Aqueductal Stenosis	17%
97	Sleep Wake Disorders	16.8%
98	Giant Cell Arteritis	16.7%
99	Temporal Arteritis	16.7%
100	Hepatolenticular Degeneration	16.5%
101	Limbic Encephalitis	16.5%
102	Chronic Fatigue Syndrome	16.5%
103	Brain Death	16.3%
104	Amblyopia	16.3%
105	MPTP Poisoning	16.2%
106	Autonomic Dysreflexia	16.2%
107	Complex Regional Pain Syndromes	16.2%
108	Central Nervous System Infection	16.1%
109	Dyskinesia, Drug-Induced	15.9%
110	Cerebellar Neoplasms	15.9%
111	Leukomalacia, Periventricular	15.8%
112	Brain Diseases, Metabolic	15.5%
113	Cerebrovascular Disorders	15.5%
114	Cerebrovascular Insufficiency	15.5%
115	Dementia	15.5%
116	Meige Syndrome	15.3%
117	Cerebral Ventriculitis	15.3%
118	Brain Hemorrhage, Traumatic	15.1%
119	Adrenoleukodystrophy	15.1%
120	Akathisia, Drug-Induced	14.9%
121	Peripheral Nerve Injuries	14.8%
122	Vascular Headaches	14.5%
123	Hypoxia-Ischemia, Brain	14.5%
124	Amnesia, Transient Global	14.2%
125	Presenile dementia	14.2%
126	Senile dementia	14.2%
127	Ataxia Telangiectasia	14.1%
128	Creutzfeldt-Jakob disease	14%
129	Spinal Cord Neoplasms	13.9%
130	Sleep Disorders, Circadian Rhythm	13.8%
131	Meningitis, Bacterial	13.7%
132	Meningitis, Fungal	13.7%
133	Carotid Artery Injuries	13.7%
134	Olfactory Nerve Injuries	13.6%
135	Botulism	13.5%
136	Central Nervous System Cysts	13.5%
137	Demyelinating Diseases	13.2%
138	Demyelination	13.2%
139	Pituitary Adenoma	13.1%
140	Pituitary Neoplasms	13.1%
141	Toxoplasmosis, Cerebral	13.1%
142	Myoclonic Epilepsy	13%
143	Epilepsy, Temporal Lobe	13%
144	Epilepsy, Rolandic	13%
145	Benign Rolandic Epilepsy	13%
146	Causalgia	13%
147	Paraneoplastic Cerebellar Degeneration	13%
148	Basal Ganglia Hemorrhage	12.9%
149	Friedreich Ataxia	12.7%
150	Facial Nerve Injuries	12.6%
151	Brain Injuries, Diffuse	12.3%
152	Traumatic Brain Injury	12.3%
153	Lafora Disease	12.3%
154	Unverricht-Lundborg Syndrome	12.3%
155	Cerebellar Ataxia	12.3%
156	Supratentorial Neoplasms	12.3%
157	Progressive bulbar palsy	12.2%
158	Bulbar palsy	12.2%
159	Tuberous Sclerosis	12.2%
160	Horner Syndrome	11.8%
161	Persistent Vegetative State	11.4%
162	Dysautonomia	11.2%
163	Vagus Nerve Disorder	11.2%
164	Glossopharyngeal Neuralgia	11.2%
165	Abducens Nerve Diseases	11.2%
166	Heavy Metal Poisoning, Nervous System	11.2%
167	Neuromuscular Junction Diseases	11.2%
168	Tauopathies	11.2%
169	Trochlear Nerve Diseases	11.2%
170	Peripheral Nervous System Diseases	11.2%
171	Tuberculosis, Meningeal	11.1%
172	Scrapie	11%
173	Central Cord Syndrome	11%
174	Pituitary Apoplexy	11%
175	Jet Lag Syndrome	10.9%
176	Chorea	10.9%
177	Brain Infarction	10.9%
178	Cerebral Palsy	10.5%
179	Epilepsies, Partial	10.5%
180	Epilepsy, Generalized	10.5%
181	Pseudotumor Cerebri	10.5%
182	Hypertensive Encephalopathy	10.5%
183	Simple Partial Seizures	10.5%
184	Epilepsy, Reflex	10.5%
185	Headache Disorders, Primary	10.5%
186	Headache Disorders, Secondary	10.5%
187	Medication overuse headache	10.5%
188	Mitochondrial Encephalomyopathies	10.5%
189	Refsum Disease	10.4%
190	Antiphospholipid Syndrome	10.3%
191	Putaminal Hemorrhage	10.3%
192	Myopathy	10.3%
193	Optic Neuropathy	10.3%
194	Charcot-Marie-Tooth Disease	10.3%
195	Ophthalmoplegia	10.2%
196	External Ophthalmoplegia	10.2%
197	Reflex Sympathetic Dystrophy	10.2%
198	Nocturnal Myoclonus Syndrome	10.2%
199	Arachnoiditis	10.2%
200	Aseptic Meningitis	10.2%
201	Syringomyelia	10.2%
202	Essential Tremor	10.2%
203	Familial Tremor	10.2%
204	Pneumorrhachis	10.2%
205	Writer's Cramp	10.2%
206	Facial Nerve Diseases	10.1%
207	Craniocerebral Trauma	10.1%
208	Parasomnia	10.1%
209	Dyssomnias	10.1%
210	Juvenile Myoclonic Epilepsy	10.1%
211	Myoclonic Epilepsies, Progressive	10.1%
212	Vestibulocochlear Nerve Diseases	10.1%
213	Decerebrate State	10.1%
214	Hemiparesis	10.1%
215	Hydranencephaly	10.1%
216	Meningism	10.1%
217	Neural Tube Defects	10.1%
218	Paresis	10.1%
219	Seizures	10.1%
220	Sensation Disorders	10.1%
221	Tethered Cord Syndrome	10.1%
222	Central Nervous System Neoplasms	10.1%
223	Complex partial seizures	10.1%
224	Iniencephaly	10.1%
225	Craniorachischisis	10.1%
226	Exencephaly	10.1%
227	Monoparesis	10.1%
228	Septo-Optic Dysplasia	10.1%
229	Cortical Dysplasia	10.1%
230	Neurogenic Inflammation	10.1%
231	Gait Disorders, Neurologic	10.1%
232	Neuromuscular Manifestations	10.1%
233	Malformations of Cortical Development	10.1%
234	Sweating, Gustatory	10%
235	Auriculotemporal Syndrome	10%
236	Brain Concussion	9.8%
237	Infarction, Middle Cerebral Artery	9.8%
238	Infarction, Anterior Cerebral Artery	9.8%
239	Infarction, Posterior Cerebral Artery	9.8%
240	Vertebral Artery Dissection	9.7%
241	Auditory Perceptual Disorders	9.7%
242	Pituitary Diseases	9.7%
243	MELAS Syndrome	9.5%
244	Vocal Cord Paralysis	9.5%
245	Alice in Wonderland Syndrome	9.5%
246	Carotid Artery Diseases	9.5%
247	Brain Ischemia	9.5%
248	Cerebrovascular accident	9.5%
249	Kluver-Bucy Syndrome	9.5%
250	Vasospasm, Intracranial	9.5%
251	Intracranial Arterial Diseases	9.5%
252	Subarachnoid Hemorrhage, Traumatic	9.5%
253	Carotid Artery, Internal, Dissection	9.5%
254	Lupus Erythematosus, Systemic	9.4%
255	Overlap syndrome	9.4%
256	Autoimmune Lymphoproliferative Syndrome	9.3%
257	Pupil Disorders	9.3%
258	Neurobehavioral Manifestations	9.3%
259	Addison Disease	9.3%
260	Pemphigus	9.3%
261	Autoimmune thyroiditis	9.3%
262	Primary Adrenal Insufficiency	9.3%
263	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	9.3%
264	Autoimmune hepatitis	9.3%
265	Acrodynia	9.3%
266	Central Nervous System Fungal Infections	9.2%
267	Conus Medullaris Syndrome	9.2%
268	Spinal Cord Vascular Diseases	9.2%
269	Paraneoplastic Encephalomyelitis	9.2%
270	Subacute Sclerosing Panencephalitis	9.2%
271	Sturge-Weber Syndrome	9.1%
272	Vertigo	9.1%
273	Alcohol-Induced Disorders, Nervous System	9.1%
274	Torticollis	9.1%
275	Kernicterus	9.1%
276	Myotonic Dystrophy	8.9%
277	Moyamoya Disease	8.9%
278	Frontotemporal dementia	8.9%
279	Diffuse Axonal Injury	8.8%
280	Brain Stem Neoplasms	8.8%
281	Alcohol Withdrawal Seizures	8.7%
282	AIDS Dementia Complex	8.7%
283	Reye Syndrome	8.6%
284	Intracranial Embolism and Thrombosis	8.6%
285	Hepatic Encephalopathy	8.6%
286	Optic Nerve Glioma	8.6%
287	Myotonia Congenita	8.5%
288	Latent Autoimmune Diabetes in Adults	8.5%
289	Voice Disorders	8.5%
290	Voice Disturbance	8.5%
291	Cerebrospinal Fluid Otorrhea	8.5%
292	Cerebrospinal Fluid Rhinorrhea	8.5%
293	Dermatitis Herpetiformis	8.5%
294	Meningitis, Cryptococcal	8.5%
295	Gait Ataxia	8.5%
296	Central Nervous System Bacterial Infections	8.5%
297	Meningitis, Listeria	8.5%
298	Meningitis, Haemophilus	8.5%
299	Meningitis, Pneumococcal	8.5%
300	Cerebral Infarction	8.4%
301	Brain Stem Infarctions	8.4%
302	Smith-Magenis syndrome	8.4%
303	Dural Arteriovenous Fistula	8.4%
304	Autoimmune thrombocytopenia	8.3%
305	Immune thrombocytopenic purpura	8.3%
306	Brachial Plexus Neuritis	8.2%
307	Neuralgic Amyotrophy	8.2%
308	Brain Contusion	8.1%
309	Brain Diseases	8%
310	Coma, Post-Head Injury	8%
311	Brain Diseases, Metabolic, Inborn	7.9%
312	Alstrom Syndrome	7.9%
313	Akathisia	7.9%
314	Restlessness	7.9%
315	Psychomotor Agitation	7.9%
316	Rheumatoid Arthritis	7.8%
317	Juvenile arthritis	7.8%
318	Graves Disease	7.8%
319	Anti-Glomerular Basement Membrane Disease	7.7%
320	Reflex, Abnormal	7.7%
321	Hyporeflexia	7.7%
322	Hyperreflexia	7.7%
323	Tardive Dyskinesia	7.6%
324	Wernicke Encephalopathy	7.3%
325	Tarsal Tunnel Syndrome	7.3%
326	Cauda Equina Syndrome	7.3%
327	Post-Traumatic Headache	7.3%
328	Tension Headache	7.3%
329	Epilepsy, Complex Partial	7.3%
330	Migraine Disorders	7.3%
331	Abdominal Migraine	7.3%
332	Status Migrainosus	7.3%
333	Cervicogenic Headache	7.3%
334	Lateral Medullary Syndrome	7.2%
335	Acoustic Neuroma	7.1%
336	Gait Apraxia	7.1%
337	West Nile Fever	7.1%
338	Choroid Plexus Papilloma	7%
339	Amyloid Neuropathies, Familial	6.8%
340	Neuritis	6.8%
341	Polyneuritis	6.8%
342	Radiculitis	6.8%
343	Polyneuropathy	6.8%
344	Mononeuritis	6.8%
345	Mononeuropathies	6.8%
346	Brachial Plexus Neuropathies	6.8%
347	Radiculopathy	6.8%
348	Mononeuropathy Multiplex	6.8%
349	Nerve Root Compression	6.8%
350	Carpal Tunnel Syndrome	6.6%
351	neurofibroma	6.6%
352	Empty Sella Syndrome	6.6%
353	Hyperpituitarism	6.6%
354	Hypopituitarism	6.6%
355	Hypophysitis	6.6%
356	Sciatica	6.6%
357	Hematoma, Subdural	6.6%
358	Hematoma, Epidural, Cranial	6.6%
359	Cerebral Arterial Diseases	6.5%
360	Vertebrobasilar Insufficiency	6.5%
361	Basilar Artery Stenosis	6.5%
362	Vertebral Artery Stenosis	6.5%
363	Intracranial Hemorrhage, Hypertensive	6.5%
364	Transient Cerebral Ischemia	6.5%
365	Hypersensitivity	6.4%
366	Immunologic Deficiency Syndromes	6.4%
367	Immunoproliferative Disorders	6.4%
368	Immune reconstitution syndrome	6.4%
369	Immune Reconstitution Inflammatory Syndrome	6.4%
370	Myositis	6.1%
371	Optic Atrophy	6.1%
372	Optic Neuritis	6.1%
373	Papilledema	6.1%
374	Strabismus	6.1%
375	Tolosa-Hunt Syndrome	6.1%
376	Isaacs syndrome	6.1%
377	Arsenic Poisoning	6.1%
378	Myotonic Disorders	6.1%
379	Myasthenic Syndromes, Congenital	6.1%
380	Diabetic Neuropathies	6.1%
381	Facial Injuries	6.1%
382	Facial Neuralgia	6.1%
383	Diabetic Amyotrophy	6.1%
384	Diabetic Autonomic Neuropathy	6.1%
385	Sleep Talking	6.1%
386	Manganese Poisoning	6.1%
387	Sleep Disorders, Intrinsic	6.1%
388	Orthostatic intolerance	6.1%
389	Anosmia	6.1%
390	Ataxia	6.1%
391	Athetosis	6.1%
392	Catalepsy	6.1%
393	Dystonia	6.1%
394	Hemiplegia	6.1%
395	Locked-In Syndrome	6.1%
396	Meningeal Neoplasms	6.1%
397	Meningomyelocele	6.1%
398	Muscle Hypertonia	6.1%
399	Muscle hypotonia	6.1%
400	Myoclonus	6.1%
401	Myotonia	6.1%
402	Neuralgia	6.1%
403	Paraplegia	6.1%
404	Pseudobulbar Palsy	6.1%
405	Quadriplegia	6.1%
406	Spasm	6.1%
407	Spastic Paraplegia	6.1%
408	Status Epilepticus	6.1%
409	Taste Disorders	6.1%
410	Tremor	6.1%
411	Spina Bifida	6.1%
412	Monoplegia	6.1%
413	Hypokinesia	6.1%
414	Paraparesis	6.1%
415	Bradykinesia	6.1%
416	Waxy flexibility	6.1%
417	Action Tremor	6.1%
418	Resting Tremor	6.1%
419	Dysosmia	6.1%
420	Quadriparesis	6.1%
421	Mercury Poisoning, Nervous System	6.1%
422	Olfaction Disorders	6.1%
423	Myokymia	6.1%
424	Lead Poisoning, Nervous System	6.1%
425	Vestibular Neuronitis	6.1%
426	Somatosensory Disorders	6.1%
427	Neuropathic pain	6.1%
428	Hyperkinesia	6.1%
429	Intention tremor	6.1%
430	Carotid Stenosis	6%
431	Intracranial Aneurysm	6%
432	Intracranial Arteriosclerosis	5.9%
433	Cerebral Atherosclerosis	5.9%
434	Subarachnoid Hemorrhage	5.9%
435	Cerebral Arteriosclerosis	5.9%
436	Cerebral Hemorrhage	5.9%
437	Cerebral Thrombosis	5.9%
438	Intracranial Embolism	5.9%
439	Intracranial Thrombosis	5.9%
440	Spinal Cord Ischemia	5.9%
441	Tuberculosis, Central Nervous System	5.9%
442	Transfusion Reaction	5.8%
443	Hypotensive Transfusion Reaction	5.8%
444	Cubital Tunnel Syndrome	5.7%
445	Hand-Arm Vibration Syndrome	5.7%
446	Cluster Headache	5.6%
447	Migraine with Aura	5.6%
448	Familial Hemiplegic Migraine	5.6%
449	Chronic Paroxysmal Hemicrania	5.6%
450	SUNCT Syndrome	5.6%
451	Paroxysmal Hemicrania	5.6%
452	Vision Disorders	5.6%
453	Metamorphopsia	5.6%
454	Visual Impairment	5.6%
455	Fibromyalgia	5.6%
456	Optic Neuropathy, Ischemic	5.6%
457	Anterior Ischemic Optic Neuropathy	5.6%
458	Medial Tibial Stress Syndrome	5.6%
459	Facial Hemiatrophy	5.6%
460	Melkersson-Rosenthal Syndrome	5.6%
461	Mitochondrial Myopathies	5.6%
462	Anisocoria	5.6%
463	Confusion	5.6%
464	Facial paralysis	5.6%
465	Lethargy	5.6%
466	Memory Disorders	5.6%
467	Muscle Cramp	5.6%
468	Perceptual Disorders	5.6%
469	Psychomotor Disorders	5.6%
470	Tonic Pupil	5.6%
471	Eosinophilia-Myalgia Syndrome	5.6%
472	Anhedonia	5.6%
473	Disorientation	5.6%
474	Facial Paresis	5.6%
475	Memory Loss	5.6%
476	Hemisensory Neglect	5.6%
477	Dysacusis	5.6%
478	Classical Lissencephalies and Subcortical Band Heterotopias	5.6%
479	Sleep Bruxism	5.6%
480	Anencephaly	5.5%
481	Meningocele	5.5%
482	Muscular Atrophy	5.5%
483	Respiratory Paralysis	5.5%
484	Encephalocele	5.5%
485	Tetany	5.5%
486	Carotid Artery Thrombosis	5.4%
487	Fabry Disease	5.4%
488	Neuroaspergillosis	5.4%
489	Menkes Kinky Hair Syndrome	5.4%
490	Hematoma, Subdural, Intracranial	5.3%
491	Hematoma, Subdural, Chronic	5.3%
492	Hematoma, Subdural, Acute	5.3%
493	Kearns-Sayre syndrome	5.2%
494	Glomerulonephritis, Membranoproliferative	5.2%
495	Duane Retraction Syndrome	5.2%
496	Consciousness Disorders	5.1%
497	Mental Retardation	5.1%
498	Muscle Weakness	5.1%
499	Depressed Level of Consciousness	5.1%
500	Mental deficiency	5.1%
501	Intellectual Disability	5.1%
502	Mobius Syndrome	5.1%
503	Bell Palsy	5.1%
504	Catatonia	5.1%
505	Herpes Zoster Oticus	5.1%
506	Familial Periodic Paralysis	5.1%
507	Hyperprolactinemia	5.1%
508	Aphonia	5.1%
509	Sleep Deprivation	5.1%
510	Dysphonia	5.1%
511	Subclavian Steal Syndrome	5.1%
512	Pick Disease of the Brain	5.1%
513	Pseudorabies	5.1%
514	Leukoencephalopathy	5%
515	POEMS Syndrome	4.9%
516	Neurosyphilis	4.9%
517	Granulomatosis with polyangiitis	4.9%
518	Optic Atrophy, Hereditary, Leber	4.9%
519	Alexia	4.8%
520	Dyslexia	4.8%
521	Myalgia	4.7%
522	Neuronal Ceroid-Lipofuscinoses	4.7%
523	Galactosemias	4.7%
524	Urea Cycle Disorders, Inborn	4.7%
525	Tyrosinemias	4.7%
526	Acromegaly	4.6%
527	Cerebral Amyloid Angiopathy	4.6%
528	Sinus Thrombosis, Intracranial	4.6%
529	Sciatic Neuropathy	4.6%
530	Ulnar Neuropathies	4.6%
531	Lesion of Sciatic Nerve	4.6%
532	Ulnar Neuritis	4.6%
533	Radial nerve compression	4.6%
534	Radial Tunnel Syndrome	4.6%
535	Peroneal Neuropathies	4.6%
536	Radial Neuropathy	4.6%
537	Median Neuropathy	4.6%
538	Sciatic Nerve Palsy	4.6%
539	Femoral Neuropathy	4.6%
540	Tibial Neuropathy	4.6%
541	Ulnar Nerve Palsy	4.6%
542	Postural Orthostatic Tachycardia Syndrome	4.6%
543	Radial nerve palsy	4.6%
544	Waterhouse-Friderichsen Syndrome	4.6%
545	Lyme Neuroborreliosis	4.5%
546	Felty Syndrome	4.5%
547	Lupus Nephritis	4.4%
548	Neurofibrosarcoma	4.4%
549	Thrombocytopenic purpura	4.4%
550	Aicardi's syndrome	4.4%
551	Hoarseness	4.4%
552	Cockayne Syndrome	4.4%
553	Homocystinuria	4.4%
554	Alcohol Withdrawal Delirium	4.4%
555	Leigh Disease	4.4%
556	Anterior Spinal Artery Syndrome	4.3%
557	Thoracic Outlet Syndrome	4.2%
558	Esotropia	4.1%
559	Exotropia	4.1%
560	Hypotension, Orthostatic	4.1%
561	Sleep Apnea Syndromes	4.1%
562	Polymyositis	4.1%
563	Post-Exercise Hypotension	4.1%
564	Rheumatoid Vasculitis	4.1%
565	Disorders of Excessive Somnolence	4.1%
566	Sleep Initiation and Maintenance Disorders	4.1%
567	Night Terrors	4.1%
568	Somnambulism	4.1%
569	Trigeminal Nerve Disorder	4.1%
570	Transient Insomnia	4.1%
571	Sleep Paralysis	4.1%
572	Chronic Insomnia	4.1%
573	REM Sleep Behavior Disorder	4.1%
574	Hypersomnia	4.1%
575	Dermal Sinus	4.1%
576	Dysgeusia	4.1%
577	Formication	4.1%
578	Hyperalgesia	4.1%
579	Hyperesthesia	4.1%
580	Hypesthesia	4.1%
581	Language Disorders	4.1%
582	Numbness	4.1%
583	Paresthesia	4.1%
584	Paraparesis, Spastic	4.1%
585	Spina Bifida Cystica	4.1%
586	Trismus	4.1%
587	Spina Bifida Occulta	4.1%
588	Epilepsia Partialis Continua	4.1%
589	Hypogeusia	4.1%
590	Meningeal Carcinomatosis	4.1%
591	Brown-Sequard Syndrome	4.1%
592	Lissencephaly	4.1%
593	Polymicrogyria	4.1%
594	Pachygyria	4.1%
595	Schizencephaly	4.1%
596	Lockjaw	4.1%
597	Allodynia	4.1%
598	Lead Poisoning, Nervous System, Childhood	4.1%
599	Lead Poisoning, Nervous System, Adult	4.1%
600	Periventricular Nodular Heterotopia	4.1%
601	Ageusia	4.1%
602	Holoprosencephaly	4.1%
603	Cavernous Sinus Thrombosis	3.9%
604	Sagittal Sinus Thrombosis	3.9%
605	Prolactinoma	3.9%
606	Growth Hormone-Secreting Pituitary Adenoma	3.9%
607	Toxoplasmosis, Congenital	3.9%
608	Malaria, Cerebral	3.9%
609	Neurocysticercosis	3.9%
610	Sicca Syndrome	3.8%
611	Sjogren's Syndrome	3.8%
612	Eye Injuries	3.8%
613	Muscular Dystrophy	3.8%
614	Congenital nystagmus	3.8%
615	Orbital Myositis	3.8%
616	Diplopia	3.8%
617	Muscle Rigidity	3.8%
618	Muscle Spasticity	3.8%
619	Scotoma	3.8%
620	Photophobia	3.8%
621	Cogwheel Rigidity	3.8%
622	Hemifacial Spasm	3.8%
623	Amaurosis	3.8%
624	Blindness	3.8%
625	Nuchal Rigidity	3.8%
626	Pyomyositis	3.8%
627	Agnosia	3.7%
628	Apraxias	3.7%
629	Hallucinations	3.7%
630	Hemianopsia	3.7%
631	Hyperacusis	3.7%
632	Tinnitus	3.7%
633	Visual Agnosia	3.7%
634	Anosognosia	3.7%
635	Wernicke-Korsakoff Syndrome	3.7%
636	Phonophobia	3.7%
637	Hearing Loss	3.7%
638	Sarcopenia	3.7%
639	Zellweger Syndrome	3.7%
640	Nelson Syndrome	3.6%
641	Polyradiculopathy	3.5%
642	Amnesia	3.5%
643	Delirium	3.5%
644	Dissociative Amnesia	3.5%
645	Color blindness	3.5%
646	Global Amnesia	3.5%
647	Cri-du-Chat Syndrome	3.5%
648	Down Syndrome	3.5%
649	Trisomy 21	3.5%
650	Immune Complex Diseases	3.4%
651	Latex allergy	3.4%
652	Meningioma	3.4%
653	Williams Syndrome	3.4%
654	Microcephaly	3.4%
655	Macrocephaly	3.4%
656	Hypokalemic periodic paralysis	3.4%
657	Porencephaly	3.4%
658	Carbamoyl-Phosphate Synthase I Deficiency Disease	3.4%
659	Prader-Willi Syndrome	3.2%
660	Environmental Illness	3.2%
661	Phantom pain	3.2%
662	Phantom Limb Pain	3.2%
663	Glycogen storage disease type II	3.2%
664	Sleep Apnea, Obstructive	3.1%
665	Sleep Apnea, Central	3.1%
666	Narcolepsy	3.1%
667	Trigeminal Neuralgia	3.1%
668	Kleine-Levin Syndrome	3.1%
669	Agraphia	3.1%
670	Anomia	3.1%
671	Cluttering	3.1%
672	Language Development Disorders	3.1%
673	Speech Disorders	3.1%
674	Syncope	3.1%
675	Stupor	3.1%
676	Dysgraphia	3.1%
677	Presyncope	3.1%
678	Dyslalia	3.1%
679	Lymphoproliferative Disorders	3.1%
680	Paraproteinemias	3.1%
681	Lymphopenia	3.1%
682	Primary amyloidosis	3%
683	Monoclonal Gammopathy of Undetermined Significance	3%
684	Eye Burns	2.9%
685	Welander Distal Myopathy	2.9%
686	Amaurosis Fugax	2.9%
687	Blindness, Cortical	2.9%
688	Dyscalculia	2.9%
689	Rett Syndrome	2.9%
690	Deafness	2.9%
691	Hearing Loss, Sudden	2.9%
692	Gerstmann Syndrome	2.9%
693	Hearing Loss, Bilateral	2.9%
694	Hearing Loss, High-Frequency	2.9%
695	Hearing Loss, Mixed Conductive-Sensorineural	2.9%
696	Prosopagnosia	2.9%
697	Apraxia, Ideomotor	2.9%
698	Charles Bonnet Syndrome	2.9%
699	Hearing Loss, Unilateral	2.9%
700	Complete Hearing Loss	2.9%
701	Alien Hand Syndrome	2.9%
702	Deaf Mutism	2.9%
703	Hypergammaglobulinemia	2.8%
704	Agammaglobulinemia	2.8%
705	Kounis Syndrome	2.8%
706	HIV Infections	2.8%
707	Transfusion-Related Acute Lung Injury	2.8%
708	Rubinstein-Taybi Syndrome	2.8%
709	Asthma, Aspirin-Induced	2.8%
710	Dermatomyositis	2.7%
711	Corneal Scar	2.7%
712	Cataplexy	2.7%
713	Aphasia	2.6%
714	Articulation Disorders	2.6%
715	Echolalia	2.6%
716	Stuttering	2.6%
717	Dysphasia	2.6%
718	Muscular Dystrophy, Duchenne	2.6%
719	Retrograde amnesia	2.6%
720	Amnesia, Anterograde	2.6%
721	Multiple Myeloma	2.6%
722	Gaucher Disease	2.5%
723	Mutism	2.4%
724	Selective Mutism	2.4%
725	Serum Sickness	2.4%
726	Fragile X Syndrome	2.4%
727	Dysarthria	2.4%
728	Corneal Perforation	2.2%
729	Tay-Sachs Disease	2.2%
730	Alexia, Pure	2.2%
731	Niemann-Pick Disease, Type C	2.2%
732	Hydrops Fetalis	2.1%
733	anaphylaxis	2%
734	Food Allergy	2%
735	Anaphylactic shock	2%
736	Mucopolysaccharidosis II	2%
737	Respiratory Hypersensitivity	1.8%
738	Sick Building Syndrome	1.8%
739	Multiple Chemical Sensitivity	1.8%
740	Sezary Syndrome	1.8%
741	Plasmacytoma	1.8%
742	Tumor Lysis Syndrome	1.8%
743	Urticaria	1.8%
744	Vasculitis, Leukocytoclastic, Cutaneous	1.8%
745	HTLV-I Infections	1.8%
746	Job Syndrome	1.8%
747	Lymphoma	1.6%
748	Mastocytosis	1.6%
749	Drug Eruptions	1.6%
750	Chronic granulomatous disease	1.6%
751	Heavy Chain Disease	1.6%
752	Dermatitis, Allergic Contact	1.6%
753	HIV Seropositivity	1.6%
754	Acquired Immunodeficiency Syndrome	1.5%
755	AIDS related complex	1.5%
756	Infectious Mononucleosis	1.5%
757	Cryoglobulinemia	1.5%
758	AIDS-Related Opportunistic Infections	1.4%
759	Dermatitis, Atopic	1.4%
760	HIV Wasting Syndrome	1.4%
761	AIDS-Associated Nephropathy	1.4%
762	Waldenstrom Macroglobulinemia	1.3%
763	Wiskott-Aldrich Syndrome	1.3%
764	HIV-Associated Lipodystrophy Syndrome	1.3%
765	Milk Allergy	1.3%
766	Schnitzler Syndrome	1.3%
767	Wheat Hypersensitivity	1.3%
768	Mastocytosis, Systemic	1.1%
769	Angioedema	1%
770	Hodgkin Disease	1%
771	Leukemia, Plasma Cell	1%
772	Lymphoma, Non-Hodgkin	1%
773	Leukemia, T-Cell	1%
774	Acute Generalized Exanthematous Pustulosis	1%
775	Leukemia, B-Cell	1%
776	Asthma	1%
777	Composite Lymphoma	0.9%
778	Erythema Nodosum	0.9%
779	Dermatitis, Photoallergic	0.9%
780	Lymphangioleiomyomatosis	0.9%
781	Aspergillosis, Allergic Bronchopulmonary	0.9%
782	Toxic Epidermal Necrolysis	0.8%
783	Stevens-Johnson Syndrome	0.8%
784	Asthma, Exercise-Induced	0.7%
785	Status Asthmaticus	0.7%
786	Lymphoma, Follicular	0.7%
787	T-Cell Lymphoma	0.7%
788	Mantle cell lymphoma	0.7%
789	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.7%
790	Leukemia, Large Granular Lymphocytic	0.7%
791	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.7%
792	Asthma, Occupational	0.7%
793	Farmer's Lung	0.7%
794	Angioedemas, Hereditary	0.7%
795	Hay fever	0.7%
796	Rhinitis, Allergic, Perennial	0.7%
797	Hereditary Angioedema Type III	0.6%
798	Hereditary Angioedema Types I and II	0.6%
799	Lymphoma, T-Cell, Cutaneous	0.6%
800	Lymphoma, AIDS-Related	0.6%
801	Enteropathy-Associated T-Cell Lymphoma	0.6%
802	Primary Effusion Lymphoma	0.6%
803	Lymphomatoid Granulomatosis	0.5%
804	Mycosis Fungoides	0.5%
805	Lymphomatoid Papulosis	0.5%
806	Plasmablastic lymphoma	0.5%
807	Burkitt Lymphoma	0.5%

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