MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Sicca Syndrome

(UMLS:C0086981)

UMLS ID:: C0086981
MeSH ID:: D012859

Classification 1:

Name:

Musculoskeletal Diseases
MeSH Tree Number(s):: C05.550.114.154.774|C05.799.114.774

Classification 2:

Name:

Stomatognathic Diseases
MeSH Tree Number(s):: C07.465.815.929.669

Classification 3:

Name:

Eye Diseases
MeSH Tree Number(s):: C11.496.260.719

Classification 4:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.300.775.099.774

Classification 5:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.111.199.774

Synonym(s)

Sicca Syndrome

Dacryosialoadenopathy syndrome

SICCA SYNDROME

Sicca syndrome

Sicca syndrome, unspecified

sicca syndrome

sicca; syndrome

10.

syndrome; sicca

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Alendronate	FAERS: 7	US FAERS
2	Imatinib Mesylate	FAERS: 4	US FAERS
3	Pregabalin	FAERS: 4	US FAERS
4	Letrozole	FAERS: 3	US FAERS
5	Sertraline	FAERS: 2	US FAERS
6	pimecrolimus	FAERS: 2	US FAERS
7	1-(6-Fluoro-3,4-dihydro-2H-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2H-chromen-2-yl)-2-hydroxyethyl]amino]ethanol;hydron;chloride	FAERS: 1	US FAERS
8	Anastrozole	FAERS: 1	US FAERS
9	Atorvastatin	FAERS: 1	US FAERS
10	Enfuvirtide	FAERS: 1	US FAERS
11	Isotretinoin	FAERS: 1	US FAERS

Similar ADE(s)

	Name	Semantic Similarity
1	Felty Syndrome	40%
2	Rheumatoid Vasculitis	36.3%
3	Rheumatoid Nodule	34.2%
4	Juvenile arthritis	29.1%
5	Polymyalgia Rheumatica	20.4%
6	Gout	18.3%
7	Rheumatic Fever	17.6%
8	Osteoarthritis, Spine	17.3%
9	Periarthritis	15.6%
10	Arthrogryposis	14.5%
11	Cartilage Diseases	14.5%
12	Chondromalacia	14.5%
13	Arthritis, Psoriatic	14.2%
14	Xerophthalmia	14.1%
15	Lupus Erythematosus, Systemic	13.8%
16	Overlap syndrome	13.8%
17	Temporomandibular Joint Disorders	13.5%
18	Contracture	13.4%
19	Osteoarthropathy, Secondary Hypertrophic	13.4%
20	Osteoarthritis, Knee	13.1%
21	Fibromyalgia	12.6%
22	Keratoconjunctivitis Sicca	12.4%
23	Arthritis, Gouty	12.1%
24	Jaw Diseases	12.1%
25	Metatarsalgia	11.9%
26	Sacroiliitis	11.7%
27	Pectus carinatum	11.6%
28	Osteochondritis	11.5%
29	Parotitis	11.4%
30	Parotid Neoplasms	11.1%
31	Salivary Gland Fistula	10.9%
32	Salivary Gland Neoplasms	10.9%
33	Arthritis, Reactive	10.9%
34	Ankylosing spondylitis	10.7%
35	Arthritis, Infectious	10.4%
36	Arthritis, Experimental	10.3%
37	Foot Diseases	10.2%
38	Bursitis	10%
39	Joint Instability	10%
40	Synovitis	10%
41	Joint laxity	10%
42	Frozen shoulder	10%
43	Patellofemoral Pain Syndrome	10%
44	Drooling	9.9%
45	Sialadenitis	9.9%
46	Sialometaplasia, Necrotizing	9.9%
47	Sialorrhea	9.9%
48	Temporomandibular Joint Dysfunction Syndrome	9.7%
49	Fasciitis, Plantar	9.2%
50	Bone Diseases	9.2%
51	Fasciitis	9.2%
52	Foot Deformities	9.2%
53	Ischemic contracture	8.9%
54	Dermatitis Herpetiformis	8.9%
55	Facial Hemiatrophy	8.9%
56	Melkersson-Rosenthal Syndrome	8.9%
57	Hemarthrosis	8.7%
58	Pemphigus	8.7%
59	Spondylarthropathies	8.6%
60	Dacryocystitis	8.5%
61	Lacrimal Duct Obstruction	8.5%
62	Antiphospholipid Syndrome	8.5%
63	Lupus Erythematosus, Cutaneous	8.4%
64	Panniculitis	8.4%
65	Systemic Scleroderma	8.4%
66	Morphea	8.4%
67	Tietze's Syndrome	8.3%
68	Dermatomyositis	8.3%
69	Hip Contracture	8.2%
70	Myopathy	8.1%
71	Dupuytren Contracture	8.1%
72	Nail-Patella Syndrome	8%
73	Bell Palsy	8%
74	Addison Disease	7.5%
75	Autoimmune thyroiditis	7.5%
76	Primary Adrenal Insufficiency	7.5%
77	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	7.4%
78	Autoimmune hepatitis	7.4%
79	Mouth Abnormalities	7.4%
80	Autoimmune Lymphoproliferative Syndrome	7.4%
81	Giant Cell Epulis	7.3%
82	Graves Disease	7.3%
83	Burning Mouth Syndrome	7.1%
84	Collagen Diseases	7.1%
85	Lip Diseases	7.1%
86	Microglossia	7.1%
87	Mixed Connective Tissue Disease	7.1%
88	Oral Submucous Fibrosis	7.1%
89	Periodontal Diseases	7.1%
90	Stomatitis	7.1%
91	Tongue Diseases	7.1%
92	Oral Ulcer	7.1%
93	Mucinoses	7.1%
94	Arthralgia	6.9%
95	Platybasia	6.9%
96	Polyarthralgia	6.9%
97	Lupus Nephritis	6.9%
98	Lichen Planus, Oral	6.8%
99	Maxillary Diseases	6.7%
100	Latent Autoimmune Diabetes in Adults	6.7%
101	Cutis Laxa	6.6%
102	Pectus excavatum	6.6%
103	Jaw Abnormalities	6.6%
104	Tongue Neoplasms	6.6%
105	Panniculitis, Lupus Erythematosus	6.6%
106	Facial Nerve Diseases	6.3%
107	Granulomatosis, Orofacial	6.3%
108	Palatal Neoplasms	6.3%
109	Oral candidiasis	6.2%
110	Mouth Neoplasms	6.2%
111	Oral Fistula	6.2%
112	Orbital Cellulitis	6.2%
113	Behcet Syndrome	6.2%
114	Laryngomalacia	6.1%
115	Cleft Palate	6.1%
116	Autoimmune thrombocytopenia	6.1%
117	Immune thrombocytopenic purpura	6.1%
118	Prognathism	6.1%
119	Noonan Syndrome	6.1%
120	Anti-Glomerular Basement Membrane Disease	5.9%
121	Uveomeningoencephalitic Syndrome	5.9%
122	Klippel-Feil Syndrome	5.9%
123	Synostosis	5.9%
124	Talipes	5.9%
125	Tooth Loss	5.8%
126	Lupus Vasculitis, Central Nervous System	5.7%
127	Marfan Syndrome	5.6%
128	Facial paralysis	5.5%
129	Facial Paresis	5.5%
130	Retinal Dysplasia	5.5%
131	Hemifacial Spasm	5.5%
132	Gingival Hemorrhage	5.5%
133	Acrocephalosyndactylia	5.4%
134	Pseudoxanthoma Elasticum	5.4%
135	Craniosynostosis	5.3%
136	Syndactyly	5.3%
137	Brachycephaly	5.3%
138	Alveolar Bone Loss	5.3%
139	Bone Diseases, Developmental	5.2%
140	Hyperostosis	5.2%
141	Myofascial Pain Syndromes	5.2%
142	Osteitis	5.2%
143	Osteitis Deformans	5.2%
144	Osteochondrosis	5.2%
145	Rhabdomyolysis	5.2%
146	Spinal Diseases	5.2%
147	Osteogenesis Imperfecta	5.1%
148	Gigantism	5.1%
149	Spinal Neoplasms	5.1%
150	Spondylitis	5.1%
151	Retinal Degeneration	5%
152	Cellulitis	5%
153	Lupus Erythematosus, Discoid	4.9%
154	Scleroderma, Limited	4.9%
155	Myasthenia Gravis, Autoimmune, Experimental	4.9%
156	Gingival Recession	4.9%
157	Gingival Atrophy	4.9%
158	Toxic Epidermal Necrolysis	4.9%
159	Stevens-Johnson Syndrome	4.9%
160	Aniridia	4.9%
161	Hip Dislocation	4.8%
162	Shoulder Dislocation	4.8%
163	Hip Dysplasia	4.8%
164	Asthenopia	4.8%
165	Conjunctival Diseases	4.8%
166	Corneal Diseases	4.8%
167	Eyelid Diseases	4.8%
168	Hypersensitivity	4.8%
169	Immunologic Deficiency Syndromes	4.8%
170	Immunoproliferative Disorders	4.8%
171	Arthropathy	4.8%
172	Lens Diseases	4.8%
173	Ocular Hypertension	4.8%
174	Ocular Hypotension	4.8%
175	Retinal Diseases	4.8%
176	Scleral Diseases	4.8%
177	Vitreous Detachment	4.8%
178	Posterior Vitreous Detachment	4.8%
179	Immune reconstitution syndrome	4.8%
180	Immune Reconstitution Inflammatory Syndrome	4.8%
181	Neuromyelitis Optica	4.8%
182	Orbital Myositis	4.8%
183	Retrognathia	4.8%
184	Bone Diseases, Endocrine	4.7%
185	Bone Diseases, Infectious	4.6%
186	Bone neoplasms	4.6%
187	Compartment syndromes	4.6%
188	Osteopenia	4.6%
189	Tendinitis	4.6%
190	Tendinopathy	4.6%
191	Bone Resorption	4.6%
192	Myositis	4.6%
193	Limb Deformities, Congenital	4.6%
194	Isaacs syndrome	4.6%
195	Craniofacial Abnormalities	4.6%
196	Aseptic Necrosis of Bone	4.6%
197	Myotonic Disorders	4.6%
198	Blepharophimosis	4.5%
199	Uveal Neoplasms	4.5%
200	Eyelid Neoplasms	4.4%
201	Retinal Hemorrhage	4.4%
202	Myasthenia Gravis	4.4%
203	Macrostomia	4.4%
204	Microstomia	4.4%
205	Congenital clubfoot	4.4%
206	Vertical Talus	4.4%
207	Granulomatosis with polyangiitis	4.4%
208	Craniofacial Dysostosis	4.4%
209	Tooth Diseases	4.3%
210	Micrognathism	4.3%
211	Pierre Robin Syndrome	4.3%
212	Radicular Cyst	4.3%
213	Mumps	4.3%
214	Bronchomalacia	4.3%
215	Tracheomalacia	4.3%
216	Eye Abnormalities	4.3%
217	Eye Infection	4.3%
218	Eye Manifestations	4.3%
219	Eye Neoplasms	4.3%
220	Transfusion Reaction	4.3%
221	Hypotensive Transfusion Reaction	4.3%
222	Optic Neuropathy	4.3%
223	Mandibulofacial Dysostosis	4.2%
224	Shoulder Pain	4.2%
225	Cheilitis	4.2%
226	Gingival Diseases	4.2%
227	Glossitis	4.2%
228	Macroglossia	4.2%
229	Periodontitis	4.2%
230	Aphthous Stomatitis	4.2%
231	Scleromyxedema	4.2%
232	Glossoptosis	4.2%
233	Peri-Implantitis	4.2%
234	Low Tension Glaucoma	4.1%
235	Iridocorneal endothelial syndrome	4.1%
236	Erythema Induratum	4.1%
237	Medial Tibial Stress Syndrome	4.1%
238	Mitochondrial Myopathies	4.1%
239	Muscle Cramp	4%
240	Eosinophilia-Myalgia Syndrome	4%
241	Gastroschisis	4%
242	Muscle Rigidity	4%
243	Muscle Spasticity	4%
244	Cogwheel Rigidity	4%
245	Nuchal Rigidity	4%
246	Duane Retraction Syndrome	4%
247	Stiff-Person Syndrome	4%
248	Polyradiculoneuropathy	4%
249	Polyradiculoneuritis	4%
250	Poland Syndrome	4%
251	Corneal Scar	4%
252	Maxillofacial Abnormalities	4%
253	Necrobiosis Lipoidica Diabeticorum	3.9%
254	Dermatitis, Atopic	3.9%
255	Pharyngeal Diseases	3.9%
256	Leukoencephalitis, Acute Hemorrhagic	3.8%
257	Rheumatism	3.8%
258	Ocular Motility Disorders	3.8%
259	Cyclophoria	3.8%
260	Pupil Disorders	3.8%
261	Homocystinuria	3.8%
262	Chronic Fatigue Syndrome	3.8%
263	Eye Hemorrhage	3.7%
264	Mesenteric Panniculitis	3.7%
265	Panniculitis, Peritoneal	3.7%
266	Pemphigoid, Benign Mucous Membrane	3.7%
267	Myxoid cyst	3.7%
268	Vision Disorders	3.7%
269	Metamorphopsia	3.7%
270	Visual Impairment	3.7%
271	Eye Injuries	3.7%
272	Facial Neuralgia	3.7%
273	Myxedema	3.7%
274	Glomerulonephritis, Membranoproliferative	3.7%
275	Corneal Ulcer	3.7%
276	Dental Fistula	3.7%
277	Oroantral Fistula	3.7%
278	Choroid Hemorrhage	3.7%
279	Muscle Weakness	3.7%
280	Musculoskeletal Pain	3.6%
281	Familial Periodic Paralysis	3.6%
282	Discitis	3.6%
283	Congenital Hypothyroidism	3.6%
284	Vasculitis, Central Nervous System	3.6%
285	Retinoblastoma	3.5%
286	Herpes Labialis	3.4%
287	Vesicular Stomatitis	3.4%
288	Chorioretinitis	3.4%
289	Lambert-Eaton Myasthenic Syndrome	3.3%
290	Hordeolum	3.3%
291	Mastocytosis	3.3%
292	Retinitis Pigmentosa	3.3%
293	Pigmentary retinopathy	3.3%
294	Pyoderma Gangrenosum	3.3%
295	Color blindness	3.3%
296	Eosinophilic Granuloma	3.3%
297	Keratoconjunctivitis	3.3%
298	Myalgia	3.3%
299	Ainhum	3.3%
300	Bunion	3.3%
301	Dysostoses	3.3%
302	Fibrodysplasia Ossificans Progressiva	3.3%
303	Myoglobinuria	3.3%
304	Myositis Ossificans	3.3%
305	Spinal Stenosis	3.3%
306	Spondylosis	3.3%
307	Tenosynovitis	3.3%
308	Intervertebral Disc Degeneration	3.3%
309	Multiple Sclerosis	3.3%
310	Granuloma Annulare	3.3%
311	Keloid	3.3%
312	Trachoma	3.3%
313	Antley-Bixler Syndrome Phenotype	3.3%
314	Tuberculosis, Spinal	3.2%
315	Miller Fisher Syndrome	3.2%
316	Basal Cell Nevus Syndrome	3.1%
317	Rubinstein-Taybi Syndrome	3%
318	Myotonic Dystrophy	3%
319	Thrombocytopenic purpura	3%
320	Giant Cell Arteritis	3%
321	Temporal Arteritis	3%
322	Rheumatoid Arthritis	3%
323	Mobius Syndrome	3%
324	Pars Planitis	3%
325	Herpes Zoster Oticus	3%
326	Leukoplakia, Oral	3%
327	Encephalomyelitis, Acute Disseminated	2.9%
328	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	2.9%
329	Neuritis, Autoimmune, Experimental	2.9%
330	Serum Sickness	2.9%
331	Dermatitis, Photoallergic	2.9%
332	Dermatitis, Allergic Contact	2.9%
333	Multiple Epiphyseal Dysplasia	2.9%
334	Osteochondrodysplasias	2.9%
335	Anterior Compartment Syndrome	2.9%
336	Osteomyelitis	2.9%
337	Osteoporosis	2.9%
338	Periostitis	2.9%
339	Urticaria	2.9%
340	Enthesopathy	2.9%
341	Bone Demineralization, Pathologic	2.9%
342	Post-Traumatic Osteoporosis	2.9%
343	Abdominal Compartment Syndrome	2.9%
344	Amelia	2.9%
345	Arachnodactyly	2.9%
346	Ectromelia	2.9%
347	Femur Head Necrosis	2.9%
348	Hemimelia	2.9%
349	Phocomelia	2.9%
350	Sirenomelia	2.9%
351	Polymyositis	2.9%
352	Polydactyly	2.9%
353	Brachydactyly	2.9%
354	Plagiocephaly	2.9%
355	Lower Extremity Deformities, Congenital	2.9%
356	Upper Extremity Deformities, Congenital	2.9%
357	Osteolysis	2.9%
358	Xeroderma Pigmentosum	2.9%
359	Angioid Streaks	2.8%
360	Anisometropia	2.8%
361	Aphakia	2.8%
362	Arthritis	2.8%
363	Astigmatism	2.8%
364	Blepharitis	2.8%
365	Blepharoptosis	2.8%
366	Blepharospasm	2.8%
367	Choroid Diseases	2.8%
368	Conjunctivitis	2.8%
369	Corneal edema	2.8%
370	Corneal Opacity	2.8%
371	Ectropion	2.8%
372	Enophthalmos	2.8%
373	Entropion	2.8%
374	Episcleritis	2.8%
375	Exophthalmos	2.8%
376	Glaucoma	2.8%
377	Immune Complex Diseases	2.8%
378	Iris Diseases	2.8%
379	Keratitis	2.8%
380	Keratoconus	2.8%
381	Lens dislocation	2.8%
382	Lens Subluxation	2.8%
383	Mydriasis	2.8%
384	Myopia	2.8%
385	Presbyopia	2.8%
386	Pterygium	2.8%
387	Retinal Detachment	2.8%
388	Retinitis	2.8%
389	Scleritis	2.8%
390	Uveitis	2.8%
391	Corneal Neovascularization	2.8%
392	Orbital Pseudotumor	2.8%
393	Cataract	2.8%
394	Pinguecula	2.8%
395	Polyarthritis	2.8%
396	Trichiasis	2.8%
397	Latex allergy	2.8%
398	Gingivitis	2.8%
399	Glossitis, Benign Migratory	2.8%
400	Pericoronitis	2.8%
401	Aggressive Periodontitis	2.8%
402	Gingival Overgrowth	2.8%
403	Albinism	2.8%
404	Multiple Sclerosis, Chronic Progressive	2.7%
405	Multiple Sclerosis, Relapsing-Remitting	2.7%
406	Epidermolysis Bullosa	2.7%
407	Goldenhar Syndrome	2.7%
408	Facial Nerve Injuries	2.7%
409	Guillain-Barre Syndrome	2.7%
410	Choroiditis	2.7%
411	Iridocyclitis	2.7%
412	Iritis	2.7%
413	Acanthamoeba Keratitis	2.7%
414	Keratitis, Herpetic	2.6%
415	Cytomegalovirus Retinitis	2.6%
416	Dwarfism	2.6%
417	Bacterial conjunctivitis	2.6%
418	Primary amyloidosis	2.6%
419	Monoclonal Gammopathy of Undetermined Significance	2.6%
420	Erythema Nodosum	2.6%
421	Corneal Perforation	2.6%
422	Muscular Dystrophy	2.6%
423	Drug Eruptions	2.6%
424	Pyomyositis	2.6%
425	Environmental Illness	2.6%
426	Acromegaly	2.5%
427	Joint Tuberculosis	2.5%
428	Tuberculosis, Osteoarticular	2.5%
429	Bone Tuberculosis	2.5%
430	Lymphoproliferative Disorders	2.5%
431	Anophthalmos	2.5%
432	Endophthalmitis	2.5%
433	Microphthalmos	2.5%
434	Optic Atrophy	2.5%
435	Optic Neuritis	2.5%
436	Papilledema	2.5%
437	Paraproteinemias	2.5%
438	Retinal Artery Occlusion	2.5%
439	Retinopathy of Prematurity	2.5%
440	Strabismus	2.5%
441	Tolosa-Hunt Syndrome	2.5%
442	Retinal Vasculitis	2.5%
443	Hypertensive Retinopathy	2.5%
444	Retrobulbar Hemorrhage	2.5%
445	Corneal Endothelial Cell Loss	2.5%
446	Hyphema	2.5%
447	Lymphopenia	2.5%
448	Retinal Neovascularization	2.5%
449	Vitreous Hemorrhage	2.5%
450	Acne Vulgaris	2.5%
451	Contact Dermatitis	2.5%
452	Eczema	2.5%
453	Erythema Multiforme	2.5%
454	Intertrigo	2.5%
455	Neurodermatitis	2.5%
456	Rhinophyma	2.5%
457	Perioral Dermatitis	2.5%
458	Acne	2.5%
459	Trigeminal Nerve Disorder	2.4%
460	Asthma, Aspirin-Induced	2.4%
461	Breast Diseases	2.4%
462	Bruxism	2.4%
463	Dental Leakage	2.4%
464	Dermatitis	2.4%
465	Exanthema	2.4%
466	Facial Dermatoses	2.4%
467	Hair Diseases	2.4%
468	Hand Dermatoses	2.4%
469	Hypercementosis	2.4%
470	keratoacanthoma	2.4%
471	Keratosis	2.4%
472	Malocclusion	2.4%
473	Nail Diseases	2.4%
474	Photosensitivity Disorders	2.4%
475	Prurigo	2.4%
476	Pyoderma	2.4%
477	Rosacea	2.4%
478	Sebaceous Gland Diseases	2.4%
479	Skin Diseases, Vesiculobullous	2.4%
480	Skin Ulcer	2.4%
481	Sweat Gland Diseases	2.4%
482	Tooth Crowding	2.4%
483	Tooth Discoloration	2.4%
484	Tooth Demineralization	2.4%
485	Tooth Ankylosis	2.4%
486	Skin Diseases, Papulosquamous	2.4%
487	Skin Diseases, Vascular	2.4%
488	Acneiform Eruptions	2.4%
489	Ocular Rosacea	2.4%
490	Subcorneal pustular dermatosis	2.4%
491	Erythematotelangiectatic Rosacea	2.4%
492	Papulopustular Rosacea	2.4%
493	Chronic Actinic Dermatitis	2.4%
494	Chondrodysplasia Punctata	2.3%
495	Enchondromatosis	2.3%
496	Lordosis	2.3%
497	Osteosclerosis	2.3%
498	Spondylolysis	2.3%
499	kyphosis	2.3%
500	Kashin-Beck Disease	2.3%
501	Myotonia Congenita	2.3%
502	Rickets	2.3%
503	Microcephaly	2.3%
504	Macrocephaly	2.3%
505	Hypokalemic periodic paralysis	2.3%
506	Panophthalmitis	2.2%
507	Hypergammaglobulinemia	2.2%
508	Optic Neuropathy, Ischemic	2.2%
509	Anterior Ischemic Optic Neuropathy	2.2%
510	Retinal Vein Occlusion	2.2%
511	Agammaglobulinemia	2.2%
512	Kounis Syndrome	2.2%
513	Anisocoria	2.2%
514	Diabetic Retinopathy	2.2%
515	HIV Infections	2.2%
516	Tonic Pupil	2.2%
517	Eye pain	2.2%
518	Transfusion-Related Acute Lung Injury	2.2%
519	Acrodermatitis	2.2%
520	Sebaceous Gland Neoplasms	2.2%
521	Porokeratosis	2.2%
522	Gianotti-Crosti Syndrome	2.2%
523	Keratoderma, Palmoplantar	2.2%
524	Diplopia	2.2%
525	Scotoma	2.2%
526	Photophobia	2.2%
527	Amaurosis	2.2%
528	Blindness	2.2%
529	Multiple Myeloma	2.2%
530	Dental Enamel Hypoplasia	2.2%
531	Hypodontia	2.2%
532	Dermatitis, Phototoxic	2.2%
533	Pityriasis Lichenoides et Varioliformis Acuta	2.2%
534	Pityriasis Lichenoides	2.2%
535	Phototoxicity	2.2%
536	CREST Syndrome	2.2%
537	Tooth Injuries	2.1%
538	Kearns-Sayre syndrome	2.1%
539	Myelitis, Transverse	2.1%
540	Gingival Hyperplasia	2.1%
541	Gingival Hypertrophy	2.1%
542	Skin Abnormalities	2.1%
543	Skin Diseases, Infectious	2.1%
544	Skin Neoplasms	2.1%
545	Tooth Resorption	2.1%
546	Pigmentation Disorders	2.1%
547	Pseudohypoparathyroidism	2.1%
548	Mitochondrial Encephalomyopathies	2.1%
549	Lipomatosis	2.1%
550	Pruritus	2.1%
551	Erythema	2.1%
552	Necrolytic Migratory Erythema	2.1%
553	Cutaneous Fistula	2.1%
554	Nephrogenic Fibrosing Dermopathy	2.1%
555	Nephrogenic Systemic Fibrosis	2.1%
556	Toothache	2.1%
557	Foot Ulcer	2%
558	Osteoporosis, Postmenopausal	2%
559	Xeroderma	2%
560	Ophthalmoplegia	2%
561	External Ophthalmoplegia	2%
562	Amblyopia	2%
563	anaphylaxis	1.9%
564	Food Allergy	1.9%
565	Angle Closure Glaucoma	1.9%
566	Glaucoma, Open-Angle	1.9%
567	Macular degeneration	1.9%
568	Panuveitis	1.9%
569	Retinal Drusen	1.9%
570	Retinal Necrosis Syndrome, Acute	1.9%
571	Retinoschisis	1.9%
572	Exfoliation Syndrome	1.9%
573	Anaphylactic shock	1.9%
574	Pharyngitis	1.9%
575	Melorheostosis	1.9%
576	Osteopetrosis	1.9%
577	Spondylolisthesis	1.9%
578	Angioedema	1.8%
579	Trigeminal Neuralgia	1.8%
580	Welander Distal Myopathy	1.8%
581	Urticaria Pigmentosa	1.8%
582	Mastoiditis	1.8%
583	Petrositis	1.8%
584	Acute Generalized Exanthematous Pustulosis	1.8%
585	Sezary Syndrome	1.8%
586	Ectodermal Dysplasia	1.8%
587	Nasopharyngitis	1.8%
588	Aplasia Cutis Congenita	1.8%
589	Holoprosencephaly	1.8%
590	Mucopolysaccharidosis III	1.8%
591	Optic Atrophy, Hereditary, Leber	1.8%
592	Respiratory Hypersensitivity	1.7%
593	Pharyngeal Neoplasms	1.7%
594	Aicardi's syndrome	1.7%
595	Sick Building Syndrome	1.7%
596	Multiple Chemical Sensitivity	1.7%
597	Kernicterus	1.7%
598	Erythema Infectiosum	1.7%
599	Exanthema Subitum	1.7%
600	Nasopharyngeal Neoplasms	1.6%
601	Plasmacytoma	1.6%
602	Tumor Lysis Syndrome	1.6%
603	Vasculitis, Leukocytoclastic, Cutaneous	1.6%
604	Ulcerative stomatitis	1.6%
605	Esotropia	1.6%
606	Exotropia	1.6%
607	HTLV-I Infections	1.6%
608	Sicca Syndrome	1.6%
609	Choroidal Neovascularization	1.6%
610	Sjogren's Syndrome	1.6%
611	Job Syndrome	1.6%
612	Muscular Dystrophy, Duchenne	1.6%
613	Ophthalmia Neonatorum	1.6%
614	Dermatitis, Irritant	1.6%
615	Acne Conglobata	1.6%
616	HIV-Associated Lipodystrophy Syndrome	1.6%
617	Osteomalacia	1.6%
618	Porencephaly	1.6%
619	Ataxia Telangiectasia	1.5%
620	Ichthyosis, X-Linked	1.5%
621	Opsoclonus-Myoclonus Syndrome	1.5%
622	Sjogren-Larsson Syndrome	1.5%
623	Hydrops Fetalis	1.5%
624	Ecthyma	1.5%
625	Dermatitis, Occupational	1.5%
626	Lymphoma	1.5%
627	CHARGE Syndrome	1.5%
628	Congenital nystagmus	1.5%
629	Herpes Zoster Ophthalmicus	1.5%
630	Tinea Capitis	1.5%
631	Onychomycosis	1.5%
632	Chronic granulomatous disease	1.5%
633	Heavy Chain Disease	1.5%
634	Hemianopsia	1.5%
635	HIV Seropositivity	1.5%
636	Papillon-Lefevre Disease	1.4%
637	Amaurosis Fugax	1.4%
638	Blindness, Cortical	1.4%
639	Anhidrosis	1.4%
640	Cholesteatoma	1.4%
641	Pressure Ulcer	1.4%
642	Dental caries	1.4%
643	Dental Plaque	1.4%
644	Dental Pulp Calcification	1.4%
645	Folliculitis	1.4%
646	Foot Dermatoses	1.4%
647	Gynecomastia	1.4%
648	Hypertrichosis	1.4%
649	Hypohidrosis	1.4%
650	Hypotrichosis	1.4%
651	Leg Ulcer	1.4%
652	Miliaria	1.4%
653	Parakeratosis	1.4%
654	Parapsoriasis	1.4%
655	Pityriasis	1.4%
656	Psoriasis	1.4%
657	Pulpitis	1.4%
658	Tooth Erosion	1.4%
659	Sweet Syndrome	1.4%
660	Hidradenitis	1.4%
661	Onycholysis	1.4%
662	Miliaria Rubra	1.4%
663	Hyperpigmentation	1.4%
664	Lichenoid Eruptions	1.4%
665	Chloracne	1.4%
666	Anterior uveitis	1.4%
667	Uveitis, Posterior	1.4%
668	Milk Allergy	1.4%
669	Schnitzler Syndrome	1.4%
670	Wheat Hypersensitivity	1.4%
671	Mucopolysaccharidosis II	1.4%
672	Cockayne Syndrome	1.4%
673	Lemierre Syndrome	1.4%
674	Hyperkeratosis, Epidermolytic	1.3%
675	Acquired Immunodeficiency Syndrome	1.3%
676	AIDS related complex	1.3%
677	Horner Syndrome	1.3%
678	Angioedemas, Hereditary	1.3%
679	Infectious Mononucleosis	1.3%
680	Cryoglobulinemia	1.3%
681	POEMS Syndrome	1.3%
682	Nose Neoplasms	1.3%
683	Hereditary Angioedema Type III	1.3%
684	Hereditary Angioedema Types I and II	1.3%
685	Erythema Chronicum Migrans	1.3%
686	Renal Osteodystrophy	1.3%
687	Renal rickets	1.3%
688	Acantholysis	1.2%
689	Breast Cyst	1.2%
690	Actinic keratosis	1.2%
691	Piedra	1.2%
692	Sunburn	1.2%
693	Tooth Avulsion	1.2%
694	Argyria	1.2%
695	Dental Pulp Necrosis	1.2%
696	Hirsutism	1.2%
697	Lactation Disorder	1.2%
698	Mastitis	1.2%
699	Adiposis Dolorosa	1.2%
700	Pruritus Vulvae	1.2%
701	Mastocytoma	1.2%
702	Pruritus Ani	1.2%
703	Mastocytosis, Systemic	1.2%
704	Diaper Rash	1.2%
705	AIDS-Related Opportunistic Infections	1.2%
706	HIV Wasting Syndrome	1.2%
707	Hidradenitis Suppurativa	1.2%
708	AIDS Dementia Complex	1.2%
709	AIDS-Associated Nephropathy	1.2%
710	Dermatomycoses	1.1%
711	Mucocutaneous Lymph Node Syndrome	1.1%
712	Skin Diseases, Bacterial	1.1%
713	Lipodystrophy	1.1%
714	Tonsillitis	1.1%
715	Livedo Reticularis	1.1%
716	Malignant Atrophic Papulosis	1.1%
717	Sleep Bruxism	1.1%
718	Waldenstrom Macroglobulinemia	1.1%
719	Wiskott-Aldrich Syndrome	1.1%
720	Hodgkin Disease	1.1%
721	Leukemia, Plasma Cell	1.1%
722	Lymphoma, Non-Hodgkin	1.1%
723	Polyarteritis Nodosa	1.1%
724	Takayasu Arteritis	1.1%
725	Leukemia, T-Cell	1.1%
726	Leukemia, B-Cell	1.1%
727	MELAS Syndrome	1.1%
728	Tinea Pedis	1%
729	Ophthalmoplegic Migraine	1%
730	Progressive supranuclear palsy	1%
731	Mycetoma	1%
732	Asthma	1%
733	Nasopharyngeal carcinoma	1%
734	Porphyrias, Hepatic	1%
735	Retropharyngeal Abscess	1%
736	Hypopharyngeal Neoplasms	1%
737	Hypopharyngeal Cancer	1%
738	Composite Lymphoma	1%
739	Lymphangioleiomyomatosis	1%
740	Lichen Planus	0.9%
741	Melanosis	0.9%
742	Chloasma	0.9%
743	Pityriasis Rosea	0.9%
744	Pityriasis Rubra Pilaris	0.9%
745	Vitiligo	0.9%
746	Lichen Nitidus	0.9%
747	Asthma, Exercise-Induced	0.9%
748	Status Asthmaticus	0.9%
749	Lymphoma, Follicular	0.9%
750	T-Cell Lymphoma	0.9%
751	Mantle cell lymphoma	0.9%
752	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	0.9%
753	Leukemia, Large Granular Lymphocytic	0.9%
754	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	0.9%
755	Aspergillosis, Allergic Bronchopulmonary	0.9%
756	Alstrom Syndrome	0.9%
757	Asthma, Occupational	0.8%
758	Alopecia	0.8%
759	Sweating, Gustatory	0.8%
760	Androgenetic Alopecia	0.8%
761	Auriculotemporal Syndrome	0.8%
762	Farmer's Lung	0.8%
763	Lice Infestations	0.8%
764	Varicose Ulcer	0.8%
765	Breast Neoplasms, Male	0.8%
766	Triple Negative Breast Neoplasms	0.8%
767	Galactorrhea	0.8%
768	Hay fever	0.8%
769	Rhinitis, Allergic, Perennial	0.8%
770	Lymphoma, T-Cell, Cutaneous	0.8%
771	Lymphoma, AIDS-Related	0.8%
772	Enteropathy-Associated T-Cell Lymphoma	0.8%
773	Primary Effusion Lymphoma	0.8%
774	Optic Nerve Glioma	0.8%
775	Mycosis Fungoides	0.8%
776	Lymphomatoid Papulosis	0.8%
777	Plasmablastic lymphoma	0.8%
778	Larva Migrans	0.7%
779	Leishmaniasis	0.7%
780	Lymphomatoid Granulomatosis	0.7%
781	Molluscum Contagiosum	0.7%
782	Onchocerciasis	0.7%
783	Chromoblastomycosis	0.7%
784	Dermatophytosis	0.7%
785	Sporotrichosis	0.7%
786	Tinea	0.7%
787	Tinea Versicolor	0.7%
788	Trichophytosis	0.7%
789	Hyalohyphomycosis	0.7%
790	Familial Hypophosphatemic Rickets	0.7%
791	Acanthosis Nigricans	0.7%
792	Alopecia Areata	0.7%
793	Lentigo	0.7%
794	Warts	0.7%
795	Burkitt Lymphoma	0.7%
796	Candidiasis, Chronic Mucocutaneous	0.7%
797	Cutaneous Candidiasis	0.7%
798	Erysipelas	0.7%
799	Staphylococcal Skin Infections	0.7%
800	Variegate Porphyria	0.7%
801	Acute intermittent porphyria	0.7%
802	Porphyria Cutanea Tarda	0.7%
803	Erythrasma	0.7%
804	Carcinoma, Lobular	0.7%
805	Peritonsillar Abscess	0.7%
806	Tonsillar Neoplasms	0.6%
807	Menkes Kinky Hair Syndrome	0.6%
808	Blastomycosis	0.5%
809	Leishmaniasis, Cutaneous	0.5%
810	Eczema Herpeticum	0.5%
811	Fusariosis	0.5%
812	Rhinoscleroma	0.5%
813	Epidermodysplasia Verruciformis	0.5%
814	Diabetic Foot	0.5%
815	Staphylococcal Scalded Skin Syndrome	0.5%
816	Condylomata Acuminata	0.4%
817	Furunculosis	0.4%
818	furuncle	0.4%
819	Impetigo	0.4%
820	Peutz-Jeghers Syndrome	0.4%
821	carbuncle	0.4%

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