MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Postpericardiotomy Syndrome

(UMLS:C0032805)

Definition:: A nonspecific hypersensitivity reaction caused by TRAUMA to the PERICARDIUM, often following PERICARDIOTOMY. It is characterized by PERICARDIAL EFFUSION; high titers of anti-heart antibodies; low-grade FEVER; LETHARGY; loss of APPETITE; or ABDOMINAL PAIN.
UMLS ID:: C0032805
MeSH ID:: D011185

Classification 1:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.280.793

Classification 2:

Name:

Pathological Conditions, Signs and Symptoms
MeSH Tree Number(s):: C23.550.767.863

Synonym(s)

Postpericardiotomy Syndrome

POST CARDIOTOMY SYNDROME

POST PERICARDIOTOMY SYNDROME

POSTPERICARDIOTOMY SYNDROME

Post-Pericardiotomy Syndrome

Post-pericardiotomy syndrome

Postcardiotomy syndrome

Postcardiotomy syndrome - postoperative

Postpericardiotomy syndrome

10.

pericardiotomy post syndrome

11.

post cardiotomy syndrome

12.

post pericardiotomy syndrome

13.

post-pericardiotomy syndrome

14.

postcardiotomy syndrome

Associated Drug(s)

	Name	Number of Reports	Data Source
1	Ondansetron	FAERS: 5	US FAERS
2	Rosiglitazone	FAERS: 4	US FAERS
3	rofecoxib	FAERS: 4	OFFSIDES US FAERS
4	Amiodarone	FAERS: 1	US FAERS
5	Aprotinin	FAERS: 1 Canada Vigilance: 1	Canada Vigilance US FAERS
6	Sertraline	FAERS: 1	US FAERS
7	rasagiline	FAERS: 1	US FAERS
8	Amrinone		OFFSIDES
9	Clopidogrel		OFFSIDES
10	D-Galactosamine		OFFSIDES
11	Nabumetone		OFFSIDES
12	Ranitidine		OFFSIDES
13	cerivastatin		OFFSIDES
14	tegaserod		OFFSIDES
15	tegaserod		OFFSIDES
16	valdecoxib		OFFSIDES

Similar ADE(s)

	Name	Semantic Similarity
1	Postoperative Hemorrhage	33.9%
2	Myocardial Reperfusion Injury	33%
3	Heart Block	32.4%
4	Tachycardia	32.4%
5	Tachyarrhythmia	32.4%
6	Graft Occlusion, Vascular	31.8%
7	Surgical Wound Dehiscence	31.8%
8	Delayed Emergence from Anesthesia	31.8%
9	Anastomotic Leak	31.8%
10	Reperfusion Injury	31%
11	Vasoplegia	31%
12	Aortic Valve Stenosis	30.5%
13	Cardiomyopathy, Dilated	30.5%
14	Pulmonary Valve Stenosis	30.5%
15	Sick Sinus Syndrome	29.6%
16	Myocardial Ischemia	28.1%
17	Cardiac Tamponade	27.9%
18	Endocarditis	27.9%
19	Cardiac Arrest	27.9%
20	Heart failure	27.9%
21	Pericardial effusion	27.9%
22	Pericarditis	27.9%
23	Pneumopericardium	27.9%
24	Cor pulmonale	27.9%
25	Ventricular Outflow Obstruction	27.9%
26	Ventricular Dysfunction	27.9%
27	Cardiomyopathies	27.9%
28	Pleuropericarditis	27.9%
29	Incisional hernia	27.1%
30	Long QT Syndrome	26.8%
31	Hypertrophic Cardiomyopathy	26.4%
32	Hypertrophic obstructive cardiomyopathy	26.4%
33	Cardiac Output, High	26.3%
34	Myocardial Stunning	26.3%
35	Low Cardiac Output Syndrome	26.3%
36	Pain, Postoperative	26.1%
37	Adams-Stokes Syndrome	25.8%
38	Atrioventricular Block	25.8%
39	Bundle-Branch Block	25.8%
40	Atrial Premature Complexes	25.8%
41	Sinoatrial Block	25.8%
42	Tachycardia, Paroxysmal	25.8%
43	Supraventricular tachycardia	25.8%
44	Tachycardia, Ventricular	25.8%
45	Tachycardia, Reciprocating	25.8%
46	Failed Back Surgery Syndrome	25.5%
47	Sinus Arrhythmia	25.4%
48	Atrial Fibrillation	25.4%
49	Atrial Flutter	25.4%
50	Ventricular Fibrillation	25.4%
51	Ventricular Flutter	25.4%
52	Parasystole	25.4%
53	Paroxysmal atrial fibrillation	25.4%
54	Bradycardia	25.4%
55	Supravalvular aortic stenosis	25%
56	Lown-Ganong-Levine Syndrome	25%
57	Cardiomegaly	24.1%
58	Prosthesis Failure	24.1%
59	Cardiac Hypertrophy	24.1%
60	Corneal Endothelial Cell Loss	24.1%
61	Surgical Wound Infection	23.7%
62	Afferent Loop Syndrome	23.5%
63	Short Bowel Syndrome	23.5%
64	Tricuspid Atresia	23.5%
65	Arrhythmogenic Right Ventricular Dysplasia	23.5%
66	Sudden Cardiac Death	22.7%
67	Primary Graft Dysfunction	22.7%
68	Postoperative Nausea and Vomiting	22.7%
69	Tachycardia, Atrioventricular Nodal Reentry	22.6%
70	Tachycardia, Ectopic Atrial	22.6%
71	Tachycardia, Ectopic Junctional	22.6%
72	Sinus Tachycardia	22.6%
73	Torsades de Pointes	22.6%
74	Accelerated Idioventricular Rhythm	22.6%
75	Romano-Ward Syndrome	21.4%
76	Shock, Cardiogenic	21.3%
77	Polydipsia	21.1%
78	Ascites	20.9%
79	Fibrosis	20.9%
80	Gliosis	20.9%
81	Growth Disorders	20.9%
82	Hemorrhage	20.9%
83	Hyperbilirubinemia	20.9%
84	Hyperplasia	20.9%
85	Hypomenorrhea	20.9%
86	Inflammation	20.9%
87	Intraoperative Complications	20.9%
88	Ischemia	20.9%
89	Lithiasis	20.9%
90	Malacoplakia	20.9%
91	Menstruation Disturbances	20.9%
92	Metaplasia	20.9%
93	Nerve Degeneration	20.9%
94	Ochronosis	20.9%
95	Polymenorrhea	20.9%
96	Sclerosis	20.9%
97	Shock	20.9%
98	Ulcer	20.9%
99	Hyperammonemia	20.9%
100	Hyperamylasemia	20.9%
101	Teratogenesis	20.9%
102	Cardiac Death	20.9%
103	Hypovolemia	20.9%
104	Hyperuricemia	20.9%
105	Leukoaraiosis	20.9%
106	Dysbacteriosis	20.9%
107	Delayed Graft Function	20.9%
108	Cirrhosis	20.9%
109	Neointima	20.9%
110	Dysbiosis	20.9%
111	Aortic Valve Insufficiency	20.5%
112	Restrictive cardiomyopathy	20.5%
113	Endocardial Fibroelastosis	20.5%
114	Heart Rupture, Post-Infarction	20.5%
115	Mitral Valve Insufficiency	20.5%
116	Mitral Valve Stenosis	20.5%
117	Myocarditis	20.5%
118	Pericarditis, Constrictive	20.5%
119	Pulmonary Valve Insufficiency	20.5%
120	Tricuspid Valve Insufficiency	20.5%
121	Tricuspid Valve Stenosis	20.5%
122	Ventricular Dysfunction, Left	20.5%
123	Right Ventricular Dysfunction	20.5%
124	Endomyocardial Fibrosis	20.5%
125	Carditis	20.5%
126	Heart Failure, Systolic	20.5%
127	Heart Failure, Diastolic	20.5%
128	Rheumatic Heart Disease	20.4%
129	Coronary heart disease	20.3%
130	Infarction	20.3%
131	Myocardial Infarction	20.3%
132	Shock, Hemorrhagic	20.3%
133	Systemic Inflammatory Response Syndrome	20.3%
134	Acute Coronary Syndrome	20.3%
135	Sinus Arrest, Cardiac	20%
136	Wolff-Parkinson-White Syndrome	19.9%
137	Edema, Cardiac	18.6%
138	Angina Pectoris	17.7%
139	Left Ventricular Hypertrophy	17.6%
140	Right Ventricular Hypertrophy	17.6%
141	Dumping Syndrome	17.5%
142	Coronary Aneurysm	17.3%
143	Vascular Remodeling	16.9%
144	Aortic Valve Prolapse	16.9%
145	Tricuspid Valve Prolapse	16.9%
146	Takotsubo Cardiomyopathy	16.9%
147	Coronary Occlusion	16.7%
148	Microvascular Angina	16.7%
149	Coronary Stenosis	16.7%
150	ST segment elevation myocardial infarction	16.7%
151	Coronary Thrombosis	16.6%
152	Coronary Artery Disease	16.6%
153	Kounis Syndrome	16.4%
154	Extravasation of Diagnostic and Therapeutic Materials	16.4%
155	Neoplastic Processes	16.4%
156	Aortic coarctation	16.1%
157	Cor Triatriatum	16.1%
158	Coronary Vessel Anomalies	16.1%
159	Patent ductus arteriosus	16.1%
160	Ebstein Anomaly	16.1%
161	Heart Septal Defects	16.1%
162	Tetralogy of Fallot	16.1%
163	Transposition of Great Vessels	16.1%
164	Hypoplastic Left Heart Syndrome	16.1%
165	Necrosis	15.8%
166	Granulomatosis, Orofacial	15.8%
167	Pigmentation Disorders	15.8%
168	Respiratory Aspiration	15.8%
169	Acantholysis	15.5%
170	Chromosome Aberrations	15.5%
171	Dehydration	15.5%
172	Granuloma	15.5%
173	Leukocytosis	15.5%
174	Pleocytosis	15.5%
175	Diabetic Cardiomyopathies	15.3%
176	Cardiomyopathy, Alcoholic	15.1%
177	Chagas Cardiomyopathy	15.1%
178	Sudden infant death syndrome	15%
179	Bacterial Endocarditis	14.9%
180	Coronary Restenosis	14.9%
181	Angina, Unstable	14.7%
182	Vascular Diseases	14.6%
183	No-Reflow Phenomenon	14.3%
184	Dyspnea, Paroxysmal	14.1%
185	Menorrhagia	14%
186	Acute Disease	13.6%
187	Acute-Phase Reaction	13.6%
188	Amenorrhea	13.6%
189	Chronic disease	13.6%
190	Critical Illness	13.6%
191	Sudden death	13.6%
192	Fat necrosis	13.6%
193	Gangrene	13.6%
194	Granuloma, Plasma Cell	13.6%
195	Hematoma	13.6%
196	Iatrogenic Disease	13.6%
197	Multiple Organ Failure	13.6%
198	Oligomenorrhea	13.6%
199	Premenstrual syndrome	13.6%
200	Recurrence	13.6%
201	Retrograde Degeneration	13.6%
202	Retroperitoneal fibrosis	13.6%
203	Serositis	13.6%
204	Subcutaneous Emphysema	13.6%
205	Syndrome	13.6%
206	Wallerian Degeneration	13.6%
207	Pyogenic granuloma	13.6%
208	Exsanguination	13.6%
209	Disease Progression	13.6%
210	Seroma	13.6%
211	Premenstrual Tension	13.6%
212	Infant Death	13.6%
213	Intraoperative Awareness	13.6%
214	Chromosomal Instability	13.6%
215	jaundice	13.6%
216	Dextrocardia	13.4%
217	Carcinoid Heart Disease	13.2%
218	Aortopulmonary Septal Defect	13.2%
219	Double Outlet Right Ventricle	13.2%
220	Endocardial Cushion Defects	13.2%
221	Myocardial bridging	13.2%
222	Aorticopulmonary Septal Defect	13.2%
223	Angina Pectoris, Variant	13.2%
224	Genomic Instability	12.9%
225	Phantom pain	12.2%
226	Phantom Limb Pain	12.2%
227	Signs and Symptoms	12.2%
228	Pathological Conditions, Anatomical	12.2%
229	Dysmenorrhea	12.1%
230	Azotemia	12.1%
231	Muscle Weakness	12%
232	Truncus Arteriosus, Persistent	11.8%
233	Eye Hemorrhage	11.3%
234	Endotoxic shock	11%
235	Septic Shock	11%
236	Toxic Shock Syndrome	11%
237	Hemoptysis	11%
238	Pregnancy Complications, Cardiovascular	10.9%
239	Cardiovascular Abnormalities	10.9%
240	Ecchymosis	10.8%
241	Petechiae	10.8%
242	Purpura	10.8%
243	Asphyxia	10.7%
244	Granuloma, Respiratory Tract	10.7%
245	Shock, Traumatic	10.7%
246	Cardiotoxicity	10.4%
247	Disease susceptibility	10.3%
248	Fetal Death	10.3%
249	Foreign-Body Reaction	10.3%
250	Gastrointestinal Hemorrhage	10.3%
251	Hemarthrosis	10.3%
252	Hemoperitoneum	10.3%
253	Hemothorax	10.3%
254	Neoplasm Invasiveness	10.3%
255	Neoplasm Metastasis	10.3%
256	Neoplasm Recurrence, Local	10.3%
257	Injection Site Reaction	10.3%
258	Retrobulbar Hemorrhage	10.3%
259	Aseptic Necrosis of Bone	10.3%
260	Peritoneal Fibrosis	10.3%
261	Carcinogenesis	10.3%
262	Neurogenic Inflammation	10.3%
263	Perinatal death	10.3%
264	Infusion site reaction	10.3%
265	Nephrogenic Fibrosing Dermopathy	10.3%
266	Encapsulating Peritoneal Sclerosis	10.3%
267	Suppuration	10.3%
268	Nephrogenic Systemic Fibrosis	10.3%
269	Metastasis	10.3%
270	Arteriovenous fistula	10.3%
271	Aortic Aneurysm	10.2%
272	Aortitis	10.2%
273	Dental Pulp Necrosis	10.2%
274	Granuloma, Foreign-Body	10.2%
275	Leriche Syndrome	10.2%
276	Mediastinal Emphysema	10.2%
277	Periphlebitis	10.2%
278	Phlebitis	10.2%
279	Thromboangiitis Obliterans	10.2%
280	Facies	10.2%
281	Embryo Loss	10.2%
282	Tissue Adhesions	10.1%
283	Hematoma, Epidural, Spinal	10.1%
284	Noonan Syndrome	10.1%
285	Sex Chromosome Aberrations	10.1%
286	Uterine hemorrhage	10.1%
287	Jaundice, Obstructive	10%
288	Subacute Bacterial Endocarditis	10%
289	Chromosome Fragility	9.9%
290	Thrombophlebitis	9.6%
291	Intermittent Claudication	9.4%
292	Aneurysm	9.3%
293	Angiomatosis	9.3%
294	Aortic Diseases	9.3%
295	Arterial Occlusive Diseases	9.3%
296	Hyperemia	9.3%
297	Hypotension	9.3%
298	Superior Vena Cava Syndrome	9.3%
299	Telangiectasis	9.3%
300	Vasculitis	9.3%
301	Venous Insufficiency	9.3%
302	Peripheral Vascular Diseases	9.3%
303	Embolism and Thrombosis	9.3%
304	Angiodysplasia	9.3%
305	Capillary Leak Syndrome	9.3%
306	Prehypertension	9.3%
307	Postphlebitic Syndrome	9.2%
308	Subarachnoid Hemorrhage	9.2%
309	Cerebral Hemorrhage	9.2%
310	Epistaxis	9.2%
311	Hematoma, Subdural	9.2%
312	Hematoma, Epidural, Cranial	9.2%
313	Marfan Syndrome	9.1%
314	Embolism, Amniotic Fluid	8.8%
315	Retinal Vein Occlusion	8.6%
316	Blue Toe Syndrome	8.6%
317	Purpura, Hyperglobulinemic	8.5%
318	Drowning	8.5%
319	Trisomy	8.5%
320	Aortic Rupture	8.4%
321	Hematoma, Subdural, Spinal	8.4%
322	Aortic Aneurysm, Abdominal	8.3%
323	Aortic Aneurysm, Thoracic	8.3%
324	Fetal Growth Retardation	8.2%
325	DNA Degradation, Necrotic	8.2%
326	Aneuploidy	8.2%
327	Polyploidy	8.2%
328	Microsatellite Instability	8.2%
329	Malignant Atrophic Papulosis	8.1%
330	Cicatrix	8.1%
331	Hematuria	8.1%
332	Shwartzman Phenomenon	8.1%
333	Granuloma Annulare	8.1%
334	Chromosome Breakage	8.1%
335	May-Thurner Syndrome	8.1%
336	Brain Death	8%
337	Hematemesis	8%
338	Purpura Fulminans	7.9%
339	Carotid Artery Thrombosis	7.9%
340	Hematoma, Subdural, Intracranial	7.8%
341	Hematoma, Subdural, Chronic	7.8%
342	Hematoma, Subdural, Acute	7.8%
343	Cross Infection	7.7%
344	Hyphema	7.7%
345	Retinal Neovascularization	7.7%
346	Septicemia	7.7%
347	Vitreous Hemorrhage	7.7%
348	Sepsis	7.7%
349	Abscess	7.6%
350	Empyema	7.6%
351	Femur Head Necrosis	7.6%
352	Fetal Resorption	7.6%
353	Lymphatic Metastasis	7.6%
354	Neoplasms, Unknown Primary	7.6%
355	Peptic Ulcer Hemorrhage	7.6%
356	Leukemic Infiltration	7.6%
357	Premenstrual Dysphoric Disorder	7.6%
358	Choroidal Neovascularization	7.6%
359	Neoplasm Micrometastasis	7.6%
360	Cicatrix, Hypertrophic	7.5%
361	Williams Syndrome	7.5%
362	Metrorrhagia	7.5%
363	Intracranial Embolism and Thrombosis	7.3%
364	Carotid Stenosis	7.3%
365	Intracranial Aneurysm	7.3%
366	Vascular System Injuries	7.3%
367	Moyamoya Disease	7.3%
368	Compartment syndromes	7%
369	Hepatic Veno-Occlusive Disease	7%
370	Peliosis Hepatis	7%
371	Varicocele	7%
372	Asthenia	7%
373	Body Temperature Changes	7%
374	Calculi	7%
375	Cyanosis	7%
376	Edema	7%
377	Failure to Thrive	7%
378	Fatigue	7%
379	Feminization	7%
380	Fetal Distress	7%
381	Hernia	7%
382	Hypertrophy	7%
383	Motion Sickness	7%
384	Nails, Malformed	7%
385	polyps	7%
386	Rupture, Spontaneous	7%
387	Signs and Symptoms, Digestive	7%
388	Signs and Symptoms, Respiratory	7%
389	Skin Manifestations	7%
390	Chills	7%
391	Lassitude	7%
392	Enterocele	7%
393	Atheroma	7%
394	Pseudophakia	7%
395	Urological Manifestations	7%
396	Stenosis	7%
397	Facial asymmetry	7%
398	Mobility Limitation	7%
399	Somnolence	7%
400	Plaque, Amyloid	7%
401	Plaque, Atherosclerotic	7%
402	Cerebrovascular Disorders	6.9%
403	Diabetic Angiopathies	6.9%
404	Splenic Infarction	6.9%
405	Cerebrovascular Insufficiency	6.9%
406	Vascular Neoplasms	6.9%
407	Spinal Cord Vascular Diseases	6.9%
408	Basal Ganglia Hemorrhage	6.9%
409	Giant Cell Epulis	6.9%
410	Hemorrhoids	6.8%
411	Thoracic Outlet Syndrome	6.8%
412	Aneurysm, Dissecting	6.8%
413	Arteriosclerosis	6.8%
414	Arteritis	6.8%
415	Embolism	6.8%
416	Erythromelalgia	6.8%
417	Fibromuscular Dysplasia	6.8%
418	Malignant Hypertension	6.8%
419	Raynaud Disease	6.8%
420	Thromboembolism	6.8%
421	Thrombosis	6.8%
422	Essential Hypertension	6.8%
423	Aneurysm, Ruptured	6.8%
424	Iliac Aneurysm	6.8%
425	Pulmonary artery stenosis	6.8%
426	White Coat Hypertension	6.8%
427	Systemic Vasculitis	6.8%
428	Embolus	6.8%
429	Livedo Reticularis	6.8%
430	Polyarteritis Nodosa	6.7%
431	Takayasu Arteritis	6.7%
432	Viremia	6.6%
433	Parasitemia	6.6%
434	Intracranial Arteriosclerosis	6.6%
435	Cerebral Atherosclerosis	6.6%
436	Cerebral Arteriosclerosis	6.6%
437	Micronuclei, Chromosome-Defective	6.6%
438	Cerebral Thrombosis	6.2%
439	Intracranial Embolism	6.2%
440	Intracranial Thrombosis	6.2%
441	Putaminal Hemorrhage	6.2%
442	Retinal Hemorrhage	6.2%
443	Choroid Hemorrhage	6.1%
444	Melena	6.1%
445	Postpartum Hemorrhage	6%
446	Scimitar Syndrome	6%
447	Gingival Hemorrhage	6%
448	Keloid	6%
449	Monosomy	6%
450	Tetraploidy	6%
451	Stillbirth	6%
452	Abdominal Pain	5.9%
453	Subacute Combined Degeneration	5.8%
454	Thrombocytopenic purpura	5.8%
455	Vasculitis, Central Nervous System	5.8%
456	Eosinophilic Granuloma	5.7%
457	Sinus Thrombosis, Intracranial	5.7%
458	Hand-Arm Vibration Syndrome	5.7%
459	Arteriosclerosis Obliterans	5.6%
460	Atherosclerosis	5.6%
461	Air Embolism	5.6%
462	Endarteritis	5.6%
463	Venous Thrombosis	5.6%
464	Deep Vein Thrombosis	5.6%
465	Venous Thromboembolism	5.6%
466	Optic Neuropathy, Ischemic	5.6%
467	Anterior Ischemic Optic Neuropathy	5.6%
468	Mesenteric vascular insufficiency	5.6%
469	Lemierre Syndrome	5.5%
470	Giant Cell Arteritis	5.5%
471	Temporal Arteritis	5.5%
472	Kearns-Sayre syndrome	5.5%
473	Brain Infarction	5.5%
474	Cavernous Sinus Thrombosis	5.5%
475	Sagittal Sinus Thrombosis	5.5%
476	Cyst	5.5%
477	Eye Manifestations	5.5%
478	Neurologic Manifestations	5.5%
479	Angioedema	5.4%
480	Colitis, Ischemic	5.4%
481	Leukoplakia	5.3%
482	Reticulocytosis	5.3%
483	Airway Remodeling	5.3%
484	Infarction, Middle Cerebral Artery	5.2%
485	Infarction, Anterior Cerebral Artery	5.2%
486	Infarction, Posterior Cerebral Artery	5.2%
487	Turner Syndrome	5.2%
488	Retinal Artery Occlusion	5.2%
489	Retinal Vasculitis	5.2%
490	Hypertensive Retinopathy	5.2%
491	Ventricular Remodeling	5.2%
492	Alopecia	5.1%
493	Androgenetic Alopecia	5.1%
494	Anterior Compartment Syndrome	5.1%
495	Bacteremia	5.1%
496	Cellulitis	5.1%
497	Vasculitis, Leukocytoclastic, Cutaneous	5.1%
498	Gastric Antral Vascular Ectasia	5.1%
499	Abdominal Compartment Syndrome	5.1%
500	Kernicterus	5.1%
501	Cell Transformation, Viral	5.1%
502	Subarachnoid Hemorrhage, Traumatic	5%
503	Carotid Artery, Internal, Dissection	5%
504	Carotid Artery Diseases	5%
505	Brain Ischemia	5%
506	Ectopia Cordis	5%
507	Hypotension, Orthostatic	5%
508	Cerebrovascular accident	5%
509	Varicose Ulcer	5%
510	Vasospasm, Intracranial	5%
511	Spinal Cord Ischemia	5%
512	Intracranial Arterial Diseases	5%
513	Single umbilical artery	5%
514	Post-Exercise Hypotension	5%
515	Renal Colic	5%
516	Fungemia	5%
517	Cerebral Infarction	4.9%
518	Brain Stem Infarctions	4.9%
519	Kartagener Syndrome	4.8%
520	Eye pain	4.8%
521	Vertebral Artery Dissection	4.7%
522	Muscular Atrophy	4.7%
523	Purpura, Thrombotic Thrombocytopenic	4.7%
524	Lateral Medullary Syndrome	4.6%
525	Abdomen, Acute	4.6%
526	Anorexia	4.5%
527	Anoxia	4.5%
528	Constipation	4.5%
529	Diarrhea	4.5%
530	Dyspepsia	4.5%
531	Eructation	4.5%
532	Fever	4.5%
533	Flatulence	4.5%
534	Flushing	4.5%
535	Halitosis	4.5%
536	Heartburn	4.5%
537	Diaphragmatic Hernia	4.5%
538	Hiccough	4.5%
539	Hypercalciuria	4.5%
540	Hypercapnia	4.5%
541	Hyperphagia	4.5%
542	Intestinal Polyps	4.5%
543	Nausea	4.5%
544	Pallor	4.5%
545	Psychophysiologic Disorders	4.5%
546	Splenomegaly	4.5%
547	Vomiting	4.5%
548	Hypocapnia	4.5%
549	Dyschezia	4.5%
550	Hypoxia	4.5%
551	Hyperoxia	4.5%
552	Lower Urinary Tract Symptoms	4.5%
553	Hypoxemia	4.5%
554	Urinoma	4.5%
555	CREST Syndrome	4.5%
556	Endotoxemia	4.5%
557	Granuloma, Laryngeal	4.4%
558	Pulmonary Embolism	4.3%
559	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	4.3%
560	Hypergammaglobulinemia	4.2%
561	Cerebral Arterial Diseases	4.1%
562	Vertebrobasilar Insufficiency	4.1%
563	Anterior Spinal Artery Syndrome	4.1%
564	Basilar Artery Stenosis	4.1%
565	Vertebral Artery Stenosis	4.1%
566	Intracranial Hemorrhage, Hypertensive	4.1%
567	Transient Cerebral Ischemia	4.1%
568	Carotid Artery Injuries	4.1%
569	Mesenteric Vascular Occlusion	4.1%
570	Mucocutaneous Lymph Node Syndrome	4.1%
571	Diabetic Retinopathy	4.1%
572	Sturge-Weber Syndrome	4.1%
573	Diverticulum	4.1%
574	Diverticulosis	4.1%
575	Renal hypertension	4%
576	Renal Artery Obstruction	4%
577	Renal Artery Stenosis	4%
578	Hemangioma, Cavernous	4%
579	Basal Ganglia Cerebrovascular Disease	4%
580	Vascular Headaches	4%
581	Scurvy	4%
582	Hepatic Vein Thrombosis	3.8%
583	Budd-Chiari Syndrome	3.8%
584	Pulmonary Infarction	3.8%
585	Subclavian Steal Syndrome	3.7%
586	Autoimmune thrombocytopenia	3.7%
587	Immune thrombocytopenic purpura	3.7%
588	Sarcopenia	3.6%
589	Philadelphia Chromosome	3.6%
590	Respiratory Tract Fistula	3.6%
591	Waterhouse-Friderichsen Syndrome	3.6%
592	Apnea	3.4%
593	Cheyne-Stokes Respiration	3.4%
594	Decerebrate State	3.4%
595	Dyspnea	3.4%
596	Hemiparesis	3.4%
597	Hepatomegaly	3.4%
598	Hyperventilation	3.4%
599	Meningism	3.4%
600	Mouth Breathing	3.4%
601	Paresis	3.4%
602	Parovarian Cyst	3.4%
603	Pruritus	3.4%
604	Seizures	3.4%
605	Sensation Disorders	3.4%
606	Sneezing	3.4%
607	Spermatocele	3.4%
608	Erythema	3.4%
609	Oral Fistula	3.4%
610	Complex partial seizures	3.4%
611	Necrolytic Migratory Erythema	3.4%
612	Tachypnea	3.4%
613	Monoparesis	3.4%
614	Cutaneous Fistula	3.4%
615	Gait Disorders, Neurologic	3.4%
616	Neuromuscular Manifestations	3.4%
617	Mental Fatigue	3.4%
618	Hirsutism	3.4%
619	Dural Arteriovenous Fistula	3.4%
620	Orthostatic intolerance	3.4%
621	Hypoventilation	3.4%
622	Back Pain	3.4%
623	Bulimia	3.4%
624	Neck Pain	3.4%
625	Chest Pain	3.4%
626	Colonic Polyps	3.4%
627	Dizziness	3.4%
628	Dysuria	3.4%
629	Facial Pain	3.4%
630	Fever of Unknown Origin	3.4%
631	Flank Pain	3.4%
632	Headache	3.4%
633	Nocturia	3.4%
634	Pain, Intractable	3.4%
635	Pelvic Pain	3.4%
636	Snoring	3.4%
637	Chronic pain	3.4%
638	Lightheadedness	3.4%
639	Pain, Referred	3.4%
640	Prostatism	3.4%
641	Ischemic contracture	3.4%
642	Throbbing Headache	3.4%
643	Labor Pain	3.4%
644	Cancer Pain	3.4%
645	Nociceptive Pain	3.4%
646	Vaginal Fistula	3.4%
647	Rectocele	3.4%
648	Angioedemas, Hereditary	3.4%
649	Body Weight Changes	3.3%
650	Cryoglobulinemia	3.3%
651	Leukomalacia, Periventricular	3.3%
652	Diabetic Foot	3.3%
653	Hypertension, Renovascular	3.3%
654	Hypoxia-Ischemia, Brain	3.3%
655	Hereditary Angioedema Type III	3.3%
656	Hereditary Angioedema Types I and II	3.3%
657	Dementia, Vascular	3.3%
658	Candidemia	3.2%
659	Gait Ataxia	3%
660	Granulomatosis with polyangiitis	3%
661	Cerebral Amyloid Angiopathy	3%
662	Hoarseness	3%
663	Sleep Wake Disorders	2.9%
664	Pupil Disorders	2.9%
665	Neurobehavioral Manifestations	2.9%
666	Body Weight	2.8%
667	Shy-Drager Syndrome	2.8%
668	Emaciation	2.8%
669	Low Back Pain	2.8%
670	Visceral Pain	2.8%
671	Nasal Polyps	2.8%
672	Pituitary Apoplexy	2.8%
673	Pleural Rub	2.7%
674	Rales	2.7%
675	Respiratory Sounds	2.7%
676	Rhonchi	2.7%
677	Stridor	2.7%
678	Wheezing	2.7%
679	Asterixis	2.7%
680	Ballismus	2.7%
681	Vertigo	2.7%
682	Pain	2.7%
683	Ache	2.7%
684	Meningocele	2.7%
685	Oliguria	2.7%
686	Polyuria	2.7%
687	Proteinuria	2.7%
688	Urinary Calculi	2.7%
689	Encephalocele	2.7%
690	Underweight	2.6%
691	Overweight	2.6%
692	Akathisia	2.6%
693	Restlessness	2.6%
694	Psychomotor Agitation	2.6%
695	Biliary Fistula	2.6%
696	Gastric Fistula	2.6%
697	Congenital diaphragmatic hernia	2.6%
698	Morning Sickness	2.6%
699	Vesicovaginal Fistula	2.6%
700	Anosmia	2.5%
701	Ataxia	2.5%
702	Athetosis	2.5%
703	Catalepsy	2.5%
704	Dental Fistula	2.5%
705	Dystonia	2.5%
706	Hemiplegia	2.5%
707	Locked-In Syndrome	2.5%
708	Muscle Hypertonia	2.5%
709	Muscle hypotonia	2.5%
710	Myoclonus	2.5%
711	Myotonia	2.5%
712	Neuralgia	2.5%
713	Oroantral Fistula	2.5%
714	Paraplegia	2.5%
715	Pseudobulbar Palsy	2.5%
716	Quadriplegia	2.5%
717	Spasm	2.5%
718	Spastic Paraplegia	2.5%
719	Status Epilepticus	2.5%
720	Taste Disorders	2.5%
721	Tremor	2.5%
722	Monoplegia	2.5%
723	Hypokinesia	2.5%
724	Gastroparesis	2.5%
725	Paraparesis	2.5%
726	Bradykinesia	2.5%
727	Waxy flexibility	2.5%
728	Action Tremor	2.5%
729	Resting Tremor	2.5%
730	Dysosmia	2.5%
731	Quadriparesis	2.5%
732	Olfaction Disorders	2.5%
733	Myokymia	2.5%
734	Somatosensory Disorders	2.5%
735	Neuropathic pain	2.5%
736	Hyperkinesia	2.5%
737	Intention tremor	2.5%
738	Behcet Syndrome	2.5%
739	Lupus Vasculitis, Central Nervous System	2.5%
740	Cachexia	2.5%
741	Waldenstrom Macroglobulinemia	2.5%
742	Multiple Myeloma	2.5%
743	Rectal Prolapse	2.5%
744	Uterine Prolapse	2.5%
745	Vaginal Prolapse	2.5%
746	Weight Gain	2.5%
747	Gait Apraxia	2.5%
748	Rheumatoid Vasculitis	2.4%
749	Voice Disorders	2.3%
750	Voice Disturbance	2.3%
751	Gagging	2.3%
752	Ataxia Telangiectasia	2.3%
753	Pseudoxanthoma Elasticum	2.2%
754	Leukoplakia, Oral	2.2%
755	Umbilical hernia	2.1%
756	Toothache	2.1%
757	Alexia	2.1%
758	Vision Disorders	2.1%
759	Metamorphopsia	2.1%
760	Dyslexia	2.1%
761	Visual Impairment	2.1%
762	Hyperemesis Gravidarum	2.1%
763	Dysgeusia	2.1%
764	Formication	2.1%
765	Hyperalgesia	2.1%
766	Hyperesthesia	2.1%
767	Hypesthesia	2.1%
768	Language Disorders	2.1%
769	Numbness	2.1%
770	Paresthesia	2.1%
771	Paraparesis, Spastic	2.1%
772	Trismus	2.1%
773	Epilepsia Partialis Continua	2.1%
774	Hypogeusia	2.1%
775	Brown-Sequard Syndrome	2.1%
776	Lockjaw	2.1%
777	Allodynia	2.1%
778	Ageusia	2.1%
779	Bronchial Fistula	2.1%
780	Metatarsalgia	2.1%
781	Pancreatic Fistula	2.1%
782	Alice in Wonderland Syndrome	2%
783	Anisocoria	2%
784	Confusion	2%
785	Facial paralysis	2%
786	Intestinal Fistula	2%
787	Lethargy	2%
788	Memory Disorders	2%
789	Muscle Cramp	2%
790	Perceptual Disorders	2%
791	Psychomotor Disorders	2%
792	Tonic Pupil	2%
793	Anhedonia	2%
794	Disorientation	2%
795	Gastroschisis	2%
796	Enterocutaneous Fistula	2%
797	Fetal Hypoxia	2%
798	Facial Paresis	2%
799	Memory Loss	2%
800	Hemisensory Neglect	2%
801	Dysacusis	2%
802	Mastodynia	2%
803	Respiratory Paralysis	2%
804	Salivary Gland Fistula	2%
805	Chorea	2%
806	Cystocele	2%
807	Tetany	2%
808	Urinary Incontinence	2%
809	Breakthrough Pain	2%
810	Albuminuria	2%
811	Hemoglobinuria	2%
812	Jet Lag Syndrome	1.9%
813	Reflex, Abnormal	1.9%
814	Hyporeflexia	1.9%
815	Hyperreflexia	1.9%
816	Birth Weight	1.9%
817	Agraphia	1.9%
818	Anomia	1.9%
819	Cluttering	1.9%
820	Language Development Disorders	1.9%
821	Speech Disorders	1.9%
822	Syncope	1.9%
823	Stupor	1.9%
824	Dysgraphia	1.9%
825	Presyncope	1.9%
826	Dyslalia	1.9%
827	Aphasia	1.7%
828	Articulation Disorders	1.7%
829	Echolalia	1.7%
830	Stuttering	1.7%
831	Dysphasia	1.7%
832	Consciousness Disorders	1.7%
833	Mental Retardation	1.7%
834	Depressed Level of Consciousness	1.7%
835	Mental deficiency	1.7%
836	Intellectual Disability	1.7%
837	Catatonia	1.7%
838	Musculoskeletal Pain	1.7%
839	Ophthalmoplegia	1.7%
840	External Ophthalmoplegia	1.7%
841	Dysarthria	1.7%
842	Diplopia	1.7%
843	Muscle Rigidity	1.7%
844	Muscle Spasticity	1.7%
845	Scotoma	1.7%
846	Photophobia	1.7%
847	Cogwheel Rigidity	1.7%
848	Hemifacial Spasm	1.7%
849	Amaurosis	1.7%
850	Blindness	1.7%
851	Nuchal Rigidity	1.7%
852	Aphonia	1.7%
853	Arthralgia	1.7%
854	Sleep Deprivation	1.7%
855	Polyarthralgia	1.7%
856	Dysphonia	1.7%
857	Agnosia	1.7%
858	Apraxias	1.7%
859	Hallucinations	1.7%
860	Hemianopsia	1.7%
861	Hyperacusis	1.7%
862	Tinnitus	1.7%
863	Visual Agnosia	1.7%
864	Anosognosia	1.7%
865	Wernicke-Korsakoff Syndrome	1.7%
866	Phonophobia	1.7%
867	Hearing Loss	1.7%
868	Cerebrospinal Fluid Otorrhea	1.7%
869	Cerebrospinal Fluid Rhinorrhea	1.7%
870	Cerebellar Ataxia	1.7%
871	Torticollis	1.7%
872	Sciatica	1.6%
873	Urge Incontinence	1.6%
874	Tardive Dyskinesia	1.6%
875	Obesity	1.6%
876	Brain Hemorrhage, Traumatic	1.6%
877	Amaurosis Fugax	1.5%
878	Blindness, Cortical	1.5%
879	Dyscalculia	1.5%
880	Hydrops Fetalis	1.5%
881	Deafness	1.5%
882	Hearing Loss, Sudden	1.5%
883	Gerstmann Syndrome	1.5%
884	Hearing Loss, Bilateral	1.5%
885	Hearing Loss, High-Frequency	1.5%
886	Hearing Loss, Mixed Conductive-Sensorineural	1.5%
887	Prosopagnosia	1.5%
888	Apraxia, Ideomotor	1.5%
889	Persistent Vegetative State	1.5%
890	Charles Bonnet Syndrome	1.5%
891	Hearing Loss, Unilateral	1.5%
892	Complete Hearing Loss	1.5%
893	Alien Hand Syndrome	1.5%
894	Deaf Mutism	1.5%
895	MELAS Syndrome	1.5%
896	Vocal Cord Paralysis	1.5%
897	Fetal Weight	1.5%
898	Urinary Bladder Fistula	1.4%
899	Mutism	1.4%
900	Selective Mutism	1.4%
901	Tinea Pedis	1.4%
902	Amblyopia	1.4%
903	Amnesia	1.4%
904	Delirium	1.4%
905	Horner Syndrome	1.4%
906	Dissociative Amnesia	1.4%
907	Color blindness	1.4%
908	Global Amnesia	1.4%
909	Rectal Fistula	1.4%
910	Anal Fistula	1.4%
911	Shoulder Pain	1.4%
912	Alexia, Pure	1.4%
913	Pediatric Obesity	1.4%
914	Dyskinesia, Drug-Induced	1.3%
915	Alcohol Withdrawal Seizures	1.2%
916	Retrograde amnesia	1.2%
917	Amnesia, Anterograde	1.2%
918	Akathisia, Drug-Induced	1.2%
919	Myalgia	1.2%
920	Fabry Disease	1.1%
921	Kidney Calculi	1.1%
922	Ureteral Calculi	1.1%
923	Amnesia, Transient Global	1.1%
924	Auditory Perceptual Disorders	1%
925	Ophthalmoplegic Migraine	0.9%
926	Progressive supranuclear palsy	0.9%

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