MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Respiratory Hypersensitivity

(UMLS:C0035228)

Definition:: A form of hypersensitivity affecting the respiratory tract. It includes ASTHMA and RHINITIS, ALLERGIC, SEASONAL.
UMLS ID:: C0035228
MeSH ID:: D012130

Classification 1:

Name:

Respiratory Tract Diseases
MeSH Tree Number(s):: C08.674

Classification 2:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.543.480.680

Synonym(s)

Respiratory Hypersensitivity

respiratory hypersensitivity

Associated Drug(s)

	Name	Reference(s)	Data Source
1	1,6-hexamethylene diisocyanate	17693426 24211530	CTD
2	4,4'-diphenylmethane diisocyanate	16940033 22381623	CTD
3	4-tolyl isocyanate	16940033 17693426 22381623	CTD
4	7-aminocephalosporanic acid	24211530	CTD
5	AG 1879	30261222	CTD
6	Acetaminophen	19008617	CTD
7	Acetylcholine	9413022	CTD
8	Acrolein	30608172	CTD
9	Aspirin	15329003 20022477	CTD
10	Beclomethasone	1527319	CTD
11	Capsaicin	22575871	CTD
12	Celecoxib	15329003	CTD
13	Dinitrochlorobenzene	17693426	CTD
14	Estradiol	30445053	CTD
15	FPS-ZM1	30261222	CTD
16	Formaldehyde	15003329 29758289	CTD
17	Histamine	12095164	CTD
18	Maleic Anhydrides	24211530	CTD
19	Meloxicam	15329003	CTD
20	Methacholine Chloride	23056391	CTD
21	Nitrogen Dioxide	17135449	CTD
22	Ozone	19165401	CTD
23	Prednisolone	22575871	CTD
24	Quercetin	23873842	CTD
25	Toluene 2,4-Diisocyanate	View details 7692837 16940033 17693426 20219652 22381623 28329851 30261222 30445053	CTD
26	Vitamin E	24333275	CTD
27	ammonium hexachloroplatinate	24211530	CTD
28	chlorpyrifos-ethyl	29939342	CTD
29	diarylpropionitrile	30445053	CTD
30	diisononyl phthalate	29758289	CTD
31	disodium hexachloroplatinate	22381623	CTD
32	furfuryl alcohol	22003193	CTD
33	isophorone diisocyanate	16940033 17693426	CTD
34	methylene bis(4-cyclohexylisocyanate)	16940033	CTD
35	methylene diisocyanate	17693426	CTD
36	naringin	22575871	CTD
37	perfluorooctanoic acid	17369199	CTD
38	phthalic anhydride	20219652 22381623	CTD
39	rofecoxib	15329003	CTD
40	titanium dioxide	17656681	CTD
41	trimellitic anhydride	20219652 22381623 26732893	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	anaphylaxis	33.3%
2	Food Allergy	33.3%
3	Anaphylactic shock	33.3%
4	Milk Allergy	24.7%
5	Wheat Hypersensitivity	24.7%
6	Urticaria	24.6%
7	Asthma, Aspirin-Induced	24.5%
8	Bronchitis	24.3%
9	Pleuropneumonia	23%
10	Bronchopneumonia	22.5%
11	Immune Complex Diseases	22%
12	Latex allergy	22%
13	Pleurisy	21.8%
14	Pneumonia	21.8%
15	Lobar Pneumonia	21.8%
16	Respiratory Distress Syndrome, Adult	21.8%
17	Tracheitis	21.8%
18	Pneumonitis	21.8%
19	Bronchitis, Chronic	21.6%
20	Tracheobronchomegaly	21.4%
21	Bronchial Diseases	20.5%
22	Lung diseases	20.5%
23	Pleural Diseases	20.5%
24	Respiration Disorders	20.5%
25	Thoracic Diseases	20.5%
26	Tracheal Diseases	20.5%
27	Bronchiolitis	20%
28	Aspiration Pneumonia	17.5%
29	Laryngitis	17.4%
30	Lung Diseases, Fungal	17.4%
31	Rhinitis	17.4%
32	Vocal Cord Dysfunction	17.4%
33	Respiratory Distress Syndrome, Newborn	17.1%
34	Pleural Effusion, Malignant	17.1%
35	Granuloma, Laryngeal	17.1%
36	Bronchial Fistula	17%
37	Lung Abscess	17%
38	Lung Neoplasms	17%
39	Pleural Neoplasms	17%
40	Environmental Illness	17%
41	Tuberculosis, Pulmonary	16.9%
42	Idiopathic Pulmonary Fibrosis	16.5%
43	Laryngeal Diseases	15.7%
44	Nose Diseases	15.7%
45	Pneumonia, Lipid	15.5%
46	Sinusitis	15.5%
47	Bronchial Neoplasms	15.3%
48	Respiratory Tract Infections	15.1%
49	Bronchiolitis Obliterans	15%
50	Granuloma, Respiratory Tract	14.8%
51	Respiratory Tract Fistula	14.8%
52	Altitude Sickness	14.6%
53	Atelectasis	14.6%
54	Bronchospasm	14.6%
55	Bronchiectasis	14.6%
56	Chylothorax	14.6%
57	Hydropneumothorax	14.6%
58	Hydrothorax	14.6%
59	Pulmonary Hypertension	14.6%
60	Pneumothorax	14.6%
61	Pulmonary Alveolar Proteinosis	14.6%
62	Pulmonary Edema	14.6%
63	Pulmonary Fibrosis	14.6%
64	Respiratory Insufficiency	14.6%
65	Tracheal Stenosis	14.6%
66	Bronchial Hyperreactivity	14.6%
67	Hamman-Rich syndrome	14.6%
68	Lung Diseases, Interstitial	14.6%
69	Respiratory Depression	14.6%
70	Lung Diseases, Obstructive	14.6%
71	Respiratory Failure	14.6%
72	Angioedema	14.6%
73	Pneumoconiosis	14.5%
74	Pneumonia, Viral	14.5%
75	Choanal Atresia	14.3%
76	Laryngocele	14.3%
77	Pneumonia, Bacterial	14.1%
78	Tracheal Neoplasms	14%
79	Laryngospasm	13.9%
80	Hyaline Membrane Disease	13.8%
81	Multiple Pulmonary Nodules	13.7%
82	Dermatitis, Atopic	13.7%
83	Asthma	12.9%
84	Autoimmune Diseases	12.8%
85	Immunologic Deficiency Syndromes	12.8%
86	Immunoproliferative Disorders	12.8%
87	Immune reconstitution syndrome	12.8%
88	Immune Reconstitution Inflammatory Syndrome	12.8%
89	Kounis Syndrome	12.7%
90	Asbestosis	12.5%
91	Berylliosis	12.5%
92	Silicosis	12.5%
93	Laryngeal neoplasm	12.2%
94	Airway Obstruction	11.9%
95	Choking	11.9%
96	Epiglottitis	11.9%
97	Chronic Obstructive Airway Disease	11.9%
98	Mediastinitis	11.9%
99	Middle Lobe Syndrome	11.9%
100	Acute Lung Injury	11.9%
101	Serum Sickness	11.9%
102	Radiation Pneumonitis	11.6%
103	Radiation Fibrosis	11.6%
104	Paranasal Sinus Neoplasms	11.3%
105	Meconium Aspiration Syndrome	11.1%
106	Granuloma, Lethal Midline	10.9%
107	Laryngeal Edema	10.9%
108	Nose Deformities, Acquired	10.9%
109	Lung Injury	10.9%
110	Hepatopulmonary Syndrome	10.9%
111	Respiratory Aspiration	10.9%
112	Apnea	10.7%
113	Cheyne-Stokes Respiration	10.7%
114	Common Cold	10.7%
115	Dyspnea	10.7%
116	Hemothorax	10.7%
117	Hyperventilation	10.7%
118	Influenza	10.7%
119	Mouth Breathing	10.7%
120	Sick Building Syndrome	10.7%
121	Tachypnea	10.7%
122	Multiple Chemical Sensitivity	10.7%
123	Catarrh	10.7%
124	Pulmonary Embolism	10.6%
125	Hereditary Angioedema Type III	10.6%
126	Hereditary Angioedema Types I and II	10.6%
127	Pulmonary Emphysema	10.6%
128	Pulmonary Eosinophilia	10.6%
129	Severe Acute Respiratory Syndrome	10.6%
130	Eosinophilic Pneumonia	10.6%
131	Laryngopharyngeal Reflux	10.5%
132	Vasculitis, Leukocytoclastic, Cutaneous	10.5%
133	Transfusion-Related Acute Lung Injury	10.5%
134	Scimitar Syndrome	10.5%
135	Acute Chest Syndrome	10.2%
136	Angioedemas, Hereditary	10%
137	Maxillary Sinus Neoplasms	9.9%
138	Primary Ciliary Dyskinesia	9.8%
139	Granulomatosis with polyangiitis	9.6%
140	Hoarseness	9.4%
141	Transfusion Reaction	9.4%
142	Hypotensive Transfusion Reaction	9.4%
143	Aspergillosis, Allergic Bronchopulmonary	9.3%
144	Nose Neoplasms	9.3%
145	Rhinoscleroma	9.2%
146	Anti-Glomerular Basement Membrane Disease	9.1%
147	Mediastinal Cyst	8.9%
148	Pericardial Cyst	8.9%
149	Persistent Fetal Circulation Syndrome	8.9%
150	Thymic Cyst	8.9%
151	Croup	8.8%
152	Histiocytosis, Langerhans-Cell	8.8%
153	Mediastinal Emphysema	8.8%
154	Rhinitis, Vasomotor	8.8%
155	Pulmonary Aspergillosis	8.8%
156	Bronchopulmonary Aspergillosis	8.8%
157	Hypoventilation	8.8%
158	Acidosis, Respiratory	8.7%
159	Alkalosis, Respiratory	8.7%
160	Pharyngitis	8.7%
161	Sarcoidosis, Pulmonary	8.7%
162	Sleep Apnea Syndromes	8.7%
163	Pulmonary Infarction	8.7%
164	Laryngostenosis	8.6%
165	Nasal Polyps	8.6%
166	Blastomycosis	8.5%
167	Hemoptysis	8.5%
168	Mastocytosis	8.4%
169	Pertussis	8.4%
170	Drug Eruptions	8.3%
171	Kartagener Syndrome	8.2%
172	Dermatitis, Allergic Contact	8.2%
173	Bronchopulmonary Dysplasia	7.8%
174	Mastocytosis, Systemic	7.7%
175	Sleep Apnea, Obstructive	7.7%
176	Sleep Apnea, Central	7.7%
177	Antiphospholipid Syndrome	7.3%
178	Cystic Fibrosis	7.2%
179	Voice Disorders	7.1%
180	Voice Disturbance	7.1%
181	Glomerulonephritis, Membranoproliferative	7.1%
182	Epistaxis	7.1%
183	Tonsillitis	6.9%
184	Dyspnea, Paroxysmal	6.9%
185	Respiratory Paralysis	6.9%
186	Asthma, Exercise-Induced	6.9%
187	Status Asthmaticus	6.9%
188	Invasive Pulmonary Aspergillosis	6.2%
189	Acute Generalized Exanthematous Pustulosis	6.1%
190	Laryngomalacia	6.1%
191	Vocal Cord Paralysis	6%
192	Asthma, Occupational	5.9%
193	Autoimmune Lymphoproliferative Syndrome	5.9%
194	Aphonia	5.7%
195	Retropharyngeal Abscess	5.7%
196	Dysphonia	5.7%
197	Bronchomalacia	5.7%
198	Tracheomalacia	5.7%
199	Lupus Erythematosus, Systemic	5.5%
200	Lymphoproliferative Disorders	5.5%
201	Overlap syndrome	5.5%
202	Addison Disease	5.4%
203	Paraproteinemias	5.4%
204	Pemphigus	5.4%
205	Autoimmune thyroiditis	5.4%
206	Primary Adrenal Insufficiency	5.4%
207	Lymphopenia	5.3%
208	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	5.3%
209	Autoimmune hepatitis	5.3%
210	Farmer's Lung	5.2%
211	Erythema Nodosum	5.1%
212	Hay fever	5.1%
213	Rhinitis, Allergic, Perennial	5.1%
214	Peritonsillar Abscess	5.1%
215	Dermatitis, Photoallergic	5.1%
216	Thrombocytopenic purpura	4.9%
217	Nasopharyngitis	4.9%
218	Primary amyloidosis	4.6%
219	Monoclonal Gammopathy of Undetermined Significance	4.5%
220	Autoimmune thrombocytopenia	4.5%
221	Immune thrombocytopenic purpura	4.5%
222	Eosinophilic Granuloma	4.4%
223	Hypergammaglobulinemia	4.3%
224	Latent Autoimmune Diabetes in Adults	4.3%
225	Agammaglobulinemia	4.2%
226	Dermatitis Herpetiformis	4.2%
227	HIV Infections	4.2%
228	Toxic Epidermal Necrolysis	3.8%
229	Stevens-Johnson Syndrome	3.8%
230	Rheumatoid Arthritis	3.5%
231	Schnitzler Syndrome	3.5%
232	Juvenile arthritis	3.5%
233	Plasmacytoma	3.5%
234	Tumor Lysis Syndrome	3.5%
235	Graves Disease	3.5%
236	HTLV-I Infections	3.5%
237	Job Syndrome	3.5%
238	Multiple Myeloma	3.4%
239	Sezary Syndrome	2.9%
240	Lymphoma	2.8%
241	Myasthenia Gravis	2.8%
242	Uveomeningoencephalitic Syndrome	2.8%
243	Chronic granulomatous disease	2.8%
244	Heavy Chain Disease	2.8%
245	HIV Seropositivity	2.7%
246	Kernicterus	2.6%
247	Myasthenia Gravis, Autoimmune, Experimental	2.5%
248	Stiff-Person Syndrome	2.4%
249	Polyradiculoneuropathy	2.3%
250	Polyradiculoneuritis	2.3%
251	Ataxia Telangiectasia	2.3%
252	Acquired Immunodeficiency Syndrome	2.3%
253	AIDS related complex	2.3%
254	Infectious Mononucleosis	2.3%
255	Cryoglobulinemia	2.3%
256	Felty Syndrome	2.3%
257	POEMS Syndrome	2.3%
258	Lupus Nephritis	2.3%
259	Hydrops Fetalis	2.3%
260	Multiple Sclerosis	2.1%
261	Hodgkin Disease	2.1%
262	Leukemia, Plasma Cell	2.1%
263	Lymphoma, Non-Hodgkin	2.1%
264	Leukemia, T-Cell	2%
265	Leukemia, B-Cell	2%
266	AIDS-Related Opportunistic Infections	2%
267	Vasculitis, Central Nervous System	2%
268	HIV Wasting Syndrome	1.9%
269	Rheumatoid Vasculitis	1.9%
270	AIDS Dementia Complex	1.9%
271	AIDS-Associated Nephropathy	1.9%
272	Neuromyelitis Optica	1.8%
273	Leukoencephalitis, Acute Hemorrhagic	1.8%
274	Lupus Vasculitis, Central Nervous System	1.8%
275	Lambert-Eaton Myasthenic Syndrome	1.7%
276	Composite Lymphoma	1.7%
277	Encephalomyelitis, Acute Disseminated	1.7%
278	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	1.7%
279	Waldenstrom Macroglobulinemia	1.7%
280	Neuritis, Autoimmune, Experimental	1.7%
281	Multiple Sclerosis, Chronic Progressive	1.7%
282	Multiple Sclerosis, Relapsing-Remitting	1.7%
283	Wiskott-Aldrich Syndrome	1.7%
284	Lymphoma, Follicular	1.7%
285	T-Cell Lymphoma	1.7%
286	Mantle cell lymphoma	1.7%
287	Sicca Syndrome	1.7%
288	Sjogren's Syndrome	1.7%
289	Lymphangioleiomyomatosis	1.7%
290	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1.7%
291	Leukemia, Large Granular Lymphocytic	1.7%
292	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1.7%
293	HIV-Associated Lipodystrophy Syndrome	1.7%
294	Lymphoma, T-Cell, Cutaneous	1.5%
295	Lymphoma, AIDS-Related	1.5%
296	Enteropathy-Associated T-Cell Lymphoma	1.5%
297	Primary Effusion Lymphoma	1.5%
298	Guillain-Barre Syndrome	1.5%
299	Mycosis Fungoides	1.4%
300	Lymphomatoid Papulosis	1.4%
301	Plasmablastic lymphoma	1.4%
302	Lymphomatoid Granulomatosis	1.3%
303	Giant Cell Arteritis	1.1%
304	Temporal Arteritis	1.1%
305	Burkitt Lymphoma	1.1%
306	Myelitis, Transverse	1%
307	Miller Fisher Syndrome	0.8%

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