MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Acne Vulgaris

(UMLS:C0001144)

Definition:: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
UMLS ID:: C0001144
MeSH ID:: D000152

Classification:

Name:

Skin and Connective Tissue Diseases
MeSH Tree Number(s):: C17.800.030.150|C17.800.794.111

Synonym(s)

Acne Vulgaris

ACNE VULGARIS

Acne

Acne vulgaris

Acne;vulgaris

Common acne

acne

acne vulgaris

acne; vulgaris

10.

vulgaris; acne

Associated Drug(s)

	Name	Reference(s)	Data Source
1	4-(4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-quinoxalinyl)-1,3-thiazol-2-yl)benzoic acid	16280299	CTD
2	Adapalene	View details 8396608 9557255 9990413 12207595 15891249 17166623 17518990 21548569 21864882	CTD
3	Alcohols	9636770	CTD
4	Azelaic acid	View details 17456913 18246693 20394495 20482689 20545756 21612319 21637899 22111946	CTD
5	Benzoyl Peroxide	View details 161830 3157930 8204465 11522381 11809596 16631957 17166623 18246693 20482689	CTD
6	Betamethasone	4241782	CTD
7	Clindamycin	View details 161830 6230999 16631957 18207456 18246693 20482689 21612319	CTD
8	Cyproterone Acetate	View details 2945082 6205409 12615818 15269926	CTD
9	Cyproterone		SIDER
10	Danazol	6453071 9764869	CTD
11	Dapsone	9330049	CTD
12	Dexamethasone	16552437	CTD
13	Doxycycline	View details 12900822 15891249 17404879 19204639	CTD
14	Erythromycin	View details 6230999 11809596 20394495 20482689	CTD
15	Ethinyl Estradiol-Norgestrel Combination	4263090	CTD
16	Femovan	2096480	CTD
17	Gefitinib	17166623	CTD
18	Isoniazid	17310776	CTD
19	Isotretinoin	View details 1831820 2039732 2933136 2938008 3157930 6225882 6238241 6591112 7769163 8347155 8655244 8746368 8961893 9330049 9784036 10831665 11464180 12207595 12587200 12622636 12653758 12963905 15204147 15826276 15897376 16185265 16232082 16405632 17062097 17166623 17277875 17286159 17305209 17472998 17501969 17556790 18363422 18769834 19382995 19783054 19950851 20059367 20236286	CTD
20	Medroxyprogesterone Acetate	4261461	CTD
21	Minocycline	View details 2146526 2534972 2966976 6446663 7769163 8239326 8393461 8671830 9059695 9230019 9683157 9925852 10342897 10406406 10555598 10573723 10632948 10685779 10723699 10909633 11064276 11174376 11491116 11576401 11680122 11728996 12038730 12471353 12543195 12694504 12900849 12948923 14969661 15721822 15934105 17013846 17404879 17542873 17551382 18617786 19097002 20120014	CTD
22	Norethindrone	8222658	CTD
23	Norgestrel	View details 385243 7475634 7847530 8631187 11861056	CTD
24	Norinyl	View details 2945082 8222658 12615818 15269926 17505938	CTD
25	Oxytetracycline	8671830	CTD
26	Prednisolone	2938008	CTD
27	R 115866	21428449 21838328	CTD
28	Spironolactone	15752283	CTD
29	Tetracycline	View details 147325 6213862 6780129 10071902 17103211	CTD
30	Tretinoin	View details 161830 2146526 3156656 3157930 20233239 21274875	CTD
31	Vitamin A	View details 151668 5467368 6455256 6780129 7769163 8239326 11824142	CTD
32	Vitamin E	6455256	CTD
33	amineptin	2977080 9636770	CTD
34	dienogest	12616963	CTD
35	drospirenone and ethinyl estradiol combination	19363241	CTD
36	etonogestrel	11861056 17763263	CTD
37	nomegestrol acetate	11861056	CTD
38	norgestimate, ethinyl estradiol drug combination	9366821	CTD
39	norgestimate	17505938	CTD
40	zileuton	20436887	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Rhinophyma	53.3%
2	Pyoderma Gangrenosum	48%
3	Chloracne	44.4%
4	Sebaceous Gland Neoplasms	42.7%
5	Lupus Erythematosus, Cutaneous	41.4%
6	Panniculitis	41.4%
7	Systemic Scleroderma	41.4%
8	Morphea	41.4%
9	Breast Diseases	40.9%
10	Dermatitis	40.9%
11	Exanthema	40.9%
12	Facial Dermatoses	40.9%
13	Hair Diseases	40.9%
14	Hand Dermatoses	40.9%
15	keratoacanthoma	40.9%
16	Keratosis	40.9%
17	Nail Diseases	40.9%
18	Photosensitivity Disorders	40.9%
19	Prurigo	40.9%
20	Pyoderma	40.9%
21	Rosacea	40.9%
22	Skin Diseases, Vesiculobullous	40.9%
23	Skin Ulcer	40.9%
24	Sweat Gland Diseases	40.9%
25	Skin Diseases, Papulosquamous	40.9%
26	Skin Diseases, Vascular	40.9%
27	Ocular Rosacea	40.9%
28	Subcorneal pustular dermatosis	40.9%
29	Erythematotelangiectatic Rosacea	40.9%
30	Papulopustular Rosacea	40.9%
31	Chronic Actinic Dermatitis	40.9%
32	Contact Dermatitis	40%
33	Eczema	40%
34	Erythema Multiforme	40%
35	Intertrigo	40%
36	Neurodermatitis	40%
37	Perioral Dermatitis	40%
38	Dermatitis, Phototoxic	35.3%
39	Pityriasis Lichenoides et Varioliformis Acuta	35.3%
40	Pityriasis Lichenoides	35.3%
41	Phototoxicity	35.3%
42	Foot Ulcer	34.7%
43	Dermatitis, Atopic	34.3%
44	Epidermolysis Bullosa	34.3%
45	Dermatitis Herpetiformis	32.4%
46	Xeroderma Pigmentosum	32.2%
47	Foot Diseases	32.1%
48	Acrodermatitis	32%
49	Porokeratosis	32%
50	Gianotti-Crosti Syndrome	32%
51	Keratoderma, Palmoplantar	32%
52	Skin Abnormalities	31%
53	Skin Diseases, Infectious	31%
54	Skin Neoplasms	31%
55	Pigmentation Disorders	31%
56	Panniculitis, Lupus Erythematosus	30.8%
57	Lipomatosis	30.5%
58	Pruritus	30.5%
59	Erythema	30.5%
60	Necrolytic Migratory Erythema	30.5%
61	Cutaneous Fistula	30.5%
62	Nephrogenic Fibrosing Dermopathy	30.5%
63	Nephrogenic Systemic Fibrosis	30.5%
64	Necrobiosis Lipoidica Diabeticorum	29.8%
65	Dermatitis, Irritant	29.5%
66	Dermatitis, Photoallergic	29.3%
67	Urticaria Pigmentosa	27.5%
68	Xeroderma	27%
69	Dermatomyositis	26.9%
70	Anhidrosis	26.7%
71	Cholesteatoma	26.7%
72	Pressure Ulcer	26.7%
73	Folliculitis	26.7%
74	Foot Dermatoses	26.7%
75	Gynecomastia	26.7%
76	Hypertrichosis	26.7%
77	Hypohidrosis	26.7%
78	Hypotrichosis	26.7%
79	Leg Ulcer	26.7%
80	Lupus Erythematosus, Discoid	26.7%
81	Miliaria	26.7%
82	Parakeratosis	26.7%
83	Parapsoriasis	26.7%
84	Pityriasis	26.7%
85	Psoriasis	26.7%
86	Sweet Syndrome	26.7%
87	Hidradenitis	26.7%
88	Onycholysis	26.7%
89	Miliaria Rubra	26.7%
90	Hyperpigmentation	26.7%
91	Lichenoid Eruptions	26.7%
92	Scleroderma, Limited	26.7%
93	Erythema Induratum	25.7%
94	Dermatitis, Occupational	24.7%
95	Diaper Rash	24.4%
96	Cutis Laxa	24.3%
97	Mastocytosis	24.2%
98	Connective Tissue Diseases	23.8%
99	Dermatitis, Allergic Contact	23.7%
100	Papillon-Lefevre Disease	23.5%
101	Erythema Infectiosum	23.5%
102	Exanthema Subitum	23.3%
103	Erythema Nodosum	23%
104	Ectodermal Dysplasia	22.9%
105	Aplasia Cutis Congenita	22.9%
106	Pseudoxanthoma Elasticum	22.3%
107	Toxic Epidermal Necrolysis	22%
108	Stevens-Johnson Syndrome	22%
109	Tinea Capitis	21.2%
110	Onychomycosis	21.2%
111	Sebaceous Gland Diseases	20.5%
112	Acneiform Eruptions	20.5%
113	Acantholysis	20.3%
114	Breast Cyst	20.3%
115	Actinic keratosis	20.3%
116	Pemphigoid, Benign Mucous Membrane	20.3%
117	Pemphigus	20.3%
118	Piedra	20.3%
119	Sunburn	20.3%
120	Acne Vulgaris	20%
121	Argyria	20%
122	Hirsutism	20%
123	Lactation Disorder	20%
124	Mastitis	20%
125	Urticaria	20%
126	Acne	20%
127	Granuloma Annulare	19.9%
128	Adiposis Dolorosa	19.8%
129	Pruritus Vulvae	19.8%
130	Lichen Planus	19.8%
131	Melanosis	19.8%
132	Chloasma	19.8%
133	Pityriasis Rosea	19.8%
134	Pityriasis Rubra Pilaris	19.8%
135	Vitiligo	19.8%
136	Lichen Nitidus	19.8%
137	Mastocytoma	19.8%
138	Pruritus Ani	19.8%
139	Ecthyma	19.7%
140	Hyperkeratosis, Epidermolytic	19.4%
141	Ichthyosis, X-Linked	17.9%
142	Sjogren-Larsson Syndrome	17.8%
143	Behcet Syndrome	17.5%
144	Hidradenitis Suppurativa	16.9%
145	Acanthosis Nigricans	16.4%
146	Alopecia Areata	16.4%
147	Lentigo	16.4%
148	Dermatomycoses	16.2%
149	Mucocutaneous Lymph Node Syndrome	16.2%
150	Skin Diseases, Bacterial	16.2%
151	Drug Eruptions	16%
152	Lipodystrophy	16%
153	Livedo Reticularis	16%
154	Malignant Atrophic Papulosis	16%
155	Polyarteritis Nodosa	15.8%
156	Takayasu Arteritis	15.8%
157	Albinism	15.5%
158	Tinea Pedis	15.3%
159	Erythema Chronicum Migrans	15.2%
160	Alopecia	15.1%
161	Sweating, Gustatory	15.1%
162	Androgenetic Alopecia	15.1%
163	Auriculotemporal Syndrome	15.1%
164	Lice Infestations	14.9%
165	Varicose Ulcer	14.9%
166	Breast Neoplasms, Male	14.9%
167	Triple Negative Breast Neoplasms	14.9%
168	Acne Conglobata	14.8%
169	Galactorrhea	14.8%
170	Collagen Diseases	13.6%
171	Mixed Connective Tissue Disease	13.6%
172	Nail-Patella Syndrome	13.6%
173	Mucinoses	13.6%
174	Porphyrias, Hepatic	13.5%
175	Mycetoma	13.1%
176	Lichen Planus, Oral	12.6%
177	Larva Migrans	12.1%
178	Leishmaniasis	12.1%
179	Molluscum Contagiosum	12.1%
180	Angioedema	12%
181	Onchocerciasis	11.9%
182	Chromoblastomycosis	11.8%
183	Dermatophytosis	11.8%
184	Sporotrichosis	11.8%
185	Tinea	11.8%
186	Tinea Versicolor	11.8%
187	Trichophytosis	11.8%
188	Hyalohyphomycosis	11.8%
189	Acute Generalized Exanthematous Pustulosis	11.8%
190	Cartilage Diseases	10.7%
191	Rheumatism	10.7%
192	Chondromalacia	10.7%
193	Lupus Erythematosus, Systemic	10.3%
194	Overlap syndrome	10.3%
195	Warts	10.2%
196	Candidiasis, Chronic Mucocutaneous	9.9%
197	Cutaneous Candidiasis	9.9%
198	Erysipelas	9.8%
199	Leishmaniasis, Cutaneous	9.8%
200	Serum Sickness	9.8%
201	Staphylococcal Skin Infections	9.8%
202	Variegate Porphyria	9.8%
203	Acute intermittent porphyria	9.8%
204	Porphyria Cutanea Tarda	9.8%
205	Eczema Herpeticum	9.8%
206	Erythrasma	9.8%
207	Carcinoma, Lobular	9.8%
208	CREST Syndrome	9.8%
209	Arthritis, Psoriatic	9.8%
210	Fusariosis	9.7%
211	Scleromyxedema	8.9%
212	Hereditary Angioedema Type III	8.7%
213	Hereditary Angioedema Types I and II	8.7%
214	Giant Cell Arteritis	8.7%
215	Temporal Arteritis	8.7%
216	Angioedemas, Hereditary	8.3%
217	Epidermodysplasia Verruciformis	8.2%
218	Herpes Labialis	8.2%
219	Diabetic Foot	8.2%
220	Staphylococcal Scalded Skin Syndrome	8.1%
221	Dupuytren Contracture	8%
222	Peutz-Jeghers Syndrome	7.5%
223	Blastomycosis	7.4%
224	HIV-Associated Lipodystrophy Syndrome	7.3%
225	carbuncle	7.2%
226	Condylomata Acuminata	7.1%
227	Furunculosis	7%
228	furuncle	7%
229	Impetigo	6.9%
230	Mesenteric Panniculitis	6.8%
231	Panniculitis, Peritoneal	6.8%
232	Tietze's Syndrome	6.8%
233	Orbital Cellulitis	6.8%
234	Myxoid cyst	6.8%
235	Rhinoscleroma	6.7%
236	Cellulitis	6.7%
237	Myxedema	6.7%
238	Menkes Kinky Hair Syndrome	6.5%
239	Osteochondritis	5.5%
240	Polymyalgia Rheumatica	5.5%
241	Osteogenesis Imperfecta	5.4%
242	Keloid	5.3%
243	Noonan Syndrome	5%
244	Rheumatoid Arthritis	4.5%
245	Juvenile arthritis	4.5%
246	Marfan Syndrome	4.5%
247	Lupus Nephritis	4.4%
248	Homocystinuria	4.4%
249	Rheumatoid Nodule	3.9%
250	Laryngomalacia	3.9%
251	Pectus carinatum	3.9%
252	Felty Syndrome	3.3%
253	Bronchomalacia	3.3%
254	Tracheomalacia	3.3%
255	Rheumatoid Vasculitis	2.8%
256	Mucopolysaccharidosis III	2.8%
257	Sicca Syndrome	2.5%
258	Sjogren's Syndrome	2.5%
259	Lupus Vasculitis, Central Nervous System	2%
260	Mucopolysaccharidosis II	1.9%

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