MetaADEDB: ADE

MetaADEDB 2.0 @ LMMD

Vasculitis, Central Nervous System

(UMLS:C0751878)

Definition:: Inflammation of blood vessels within the central nervous system. Primary vasculitis is usually caused by autoimmune or idiopathic factors, while secondary vasculitis is caused by existing disease process. Clinical manifestations are highly variable but include HEADACHE; SEIZURES; behavioral alterations; INTRACRANIAL HEMORRHAGES; TRANSIENT ISCHEMIC ATTACK; and BRAIN INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, pp856-61)
UMLS ID:: C0751878
MeSH ID:: D020293

Classification 1:

Name:

Nervous System Diseases
MeSH Tree Number(s):: C10.114.875|C10.228.140.300.850

Classification 2:

Name:

Cardiovascular Diseases
MeSH Tree Number(s):: C14.907.253.946|C14.907.940.907

Classification 3:

Name:

Immune System Diseases
MeSH Tree Number(s):: C20.111.258.962

Synonym(s)

Vasculitis, Central Nervous System

Central Nervous System Vasculitis

Central nervous system vasculitis

central nervous system vasculitis

cns vasculitis

vasculitis cns

Associated Drug(s)

	Name	Reference(s)	Data Source
1	Amphetamine	1173423 1595457	CTD
2	Cocaine	View details 1750054 3656626 7502122 7555128 8650587 10069205 10815846 12935600 14513990 18839005	CTD
3	Dexamethasone	17267155	CTD
4	Methamphetamine	900566 17720598	CTD
5	Methimazole	18788922	CTD
6	Methylphenidate	16428221	CTD
7	Penicillamine	9093961	CTD
8	Phenylpropanolamine	View details 2099822 2956531 3974900 11808351	CTD
9	Propylthiouracil	15687828	CTD
10	Tacrolimus	15221068	CTD

Similar ADE(s)

	Name	Semantic Similarity
1	Moyamoya Disease	42.3%
2	Brain Infarction	41.6%
3	Infarction, Middle Cerebral Artery	39.8%
4	Infarction, Anterior Cerebral Artery	39.8%
5	Infarction, Posterior Cerebral Artery	39.8%
6	Basal Ganglia Cerebrovascular Disease	39%
7	Intracranial Embolism and Thrombosis	38.6%
8	Vascular Headaches	37.3%
9	Carotid Artery Thrombosis	37.2%
10	Dementia, Vascular	37.1%
11	Carotid Artery Injuries	36.8%
12	Subarachnoid Hemorrhage, Traumatic	36.1%
13	Carotid Artery Diseases	35.7%
14	Brain Ischemia	35.7%
15	Cerebrovascular accident	35.7%
16	Vasospasm, Intracranial	35.7%
17	Intracranial Arterial Diseases	35.7%
18	Basal Ganglia Hemorrhage	35.5%
19	Cerebral Infarction	34.8%
20	Brain Stem Infarctions	34.8%
21	Leukomalacia, Periventricular	34.7%
22	Carotid Stenosis	33.5%
23	Intracranial Aneurysm	33.5%
24	Carotid Artery, Internal, Dissection	32.8%
25	Stiff-Person Syndrome	32.1%
26	Lateral Medullary Syndrome	31.5%
27	Hypoxia-Ischemia, Brain	31.3%
28	Intracranial Arteriosclerosis	30.9%
29	Cerebral Atherosclerosis	30.9%
30	Cerebral Arteriosclerosis	30.9%
31	Putaminal Hemorrhage	30.8%
32	Aortitis	30.6%
33	Periphlebitis	30.6%
34	Phlebitis	30.6%
35	Thromboangiitis Obliterans	30.6%
36	Leukoencephalitis, Acute Hemorrhagic	30.4%
37	Cerebral Thrombosis	29.6%
38	Intracranial Embolism	29.6%
39	Intracranial Thrombosis	29.6%
40	Polyradiculoneuropathy	28.9%
41	Polyradiculoneuritis	28.9%
42	Myasthenia Gravis	27.8%
43	Vertebral Artery Dissection	27.8%
44	Myasthenia Gravis, Autoimmune, Experimental	27.3%
45	Cerebral Arterial Diseases	27%
46	Vertebrobasilar Insufficiency	27%
47	Basilar Artery Stenosis	27%
48	Vertebral Artery Stenosis	27%
49	Intracranial Hemorrhage, Hypertensive	27%
50	Transient Cerebral Ischemia	27%
51	Malignant Atrophic Papulosis	26.8%
52	Shwartzman Phenomenon	26.7%
53	Pituitary Apoplexy	26.6%
54	Thrombophlebitis	26%
55	Neuromyelitis Optica	25.2%
56	Sinus Thrombosis, Intracranial	25.2%
57	Polyarteritis Nodosa	24.9%
58	Spinal Cord Vascular Diseases	24.6%
59	Encephalomyelitis, Acute Disseminated	24.3%
60	Uveomeningoencephalitic Syndrome	24.1%
61	Subarachnoid Hemorrhage	23.5%
62	Cerebral Hemorrhage	23.5%
63	Myocardial Ischemia	23.4%
64	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis	23.1%
65	Cavernous Sinus Thrombosis	23%
66	Sagittal Sinus Thrombosis	23%
67	Aortic Aneurysm	23%
68	Leriche Syndrome	23%
69	Lambert-Eaton Myasthenic Syndrome	22.9%
70	Subclavian Steal Syndrome	22.6%
71	Arteritis	22.3%
72	Systemic Vasculitis	22.3%
73	Meningoencephalitis	22.1%
74	Brain Hemorrhage, Traumatic	22.1%
75	Guillain-Barre Syndrome	21.9%
76	Shy-Drager Syndrome	21.8%
77	Retinal Vein Occlusion	21.6%
78	Myocardial Reperfusion Injury	21.3%
79	Multiple Sclerosis	21.2%
80	Vasculitis, Leukocytoclastic, Cutaneous	21.1%
81	Polyradiculoneuropathy, Chronic Inflammatory Demyelinating	21%
82	Multiple System Atrophy	20.9%
83	Myelitis, Transverse	20.9%
84	Miller Fisher Syndrome	20.8%
85	Thoracic Outlet Syndrome	20.7%
86	Aneurysm	20.3%
87	Angiomatosis	20.3%
88	Aortic Diseases	20.3%
89	Arterial Occlusive Diseases	20.3%
90	Hyperemia	20.3%
91	Hypotension	20.3%
92	Superior Vena Cava Syndrome	20.3%
93	Telangiectasis	20.3%
94	Venous Insufficiency	20.3%
95	Peripheral Vascular Diseases	20.3%
96	Embolism and Thrombosis	20.3%
97	Angiodysplasia	20.3%
98	Capillary Leak Syndrome	20.3%
99	Prehypertension	20.3%
100	Aortic Rupture	20%
101	Postphlebitic Syndrome	20%
102	Coronary Aneurysm	19.9%
103	Takayasu Arteritis	19.9%
104	Cerebral Amyloid Angiopathy	19.7%
105	Hand-Arm Vibration Syndrome	19.5%
106	Retinal Vasculitis	19.3%
107	Lewy Body Disease	19.3%
108	Optic Neuropathy, Ischemic	19.1%
109	Anterior Ischemic Optic Neuropathy	19.1%
110	Dandy-Walker Syndrome	19%
111	Encephalomyelitis	18.4%
112	Pneumocephalus	18.1%
113	MELAS Syndrome	18.1%
114	Subdural Effusion	18.1%
115	Neuritis, Autoimmune, Experimental	18%
116	Arteriovenous fistula	18%
117	Vascular System Injuries	17.9%
118	Blue Toe Syndrome	17.8%
119	Compartment syndromes	17.6%
120	Hepatic Veno-Occlusive Disease	17.6%
121	Peliosis Hepatis	17.6%
122	Varicocele	17.6%
123	Diabetic Angiopathies	17.4%
124	Reperfusion Injury	17.4%
125	Splenic Infarction	17.4%
126	Vascular Neoplasms	17.4%
127	Vasoplegia	17.4%
128	Coronary Thrombosis	17.4%
129	Coronary Artery Disease	17.4%
130	Hemorrhoids	17.3%
131	Ataxia Telangiectasia	17.3%
132	Multiple Sclerosis, Chronic Progressive	17.1%
133	Multiple Sclerosis, Relapsing-Remitting	17.1%
134	Lupus Vasculitis, Central Nervous System	17.1%
135	Aortic Aneurysm, Abdominal	17.1%
136	Aortic Aneurysm, Thoracic	17.1%
137	Mucocutaneous Lymph Node Syndrome	16.9%
138	Endarteritis	16.7%
139	Spinal Cord Ischemia	16.7%
140	Epilepsy, Post-Traumatic	16.5%
141	Hematoma, Subdural	16.4%
142	Hematoma, Epidural, Cranial	16.4%
143	Angioedema	16.3%
144	Parkinson Disease	16.3%
145	Parkinsonian Disorders	16.2%
146	Lemierre Syndrome	16.2%
147	Posterior Leukoencephalopathy Syndrome	16.1%
148	Posterior reversible encephalopathy syndrome	16.1%
149	Kounis Syndrome	16%
150	Ocular Motility Disorders	15.7%
151	Cyclophoria	15.7%
152	Progressive supranuclear palsy	15.7%
153	Brain Abscess	15.7%
154	Sturge-Weber Syndrome	15.5%
155	Huntington Disease	15.4%
156	Striatonigral Degeneration	15.4%
157	Marchiafava-Bignami Disease	15.4%
158	Granulomatosis with polyangiitis	15.4%
159	Mesenteric vascular insufficiency	15.3%
160	Coronary heart disease	15.3%
161	Myocardial Infarction	15.3%
162	Acute Coronary Syndrome	15.3%
163	Giant Cell Arteritis	15.2%
164	Temporal Arteritis	15.2%
165	Epidural Abscess	15.1%
166	Akinetic Mutism	15.1%
167	Anoxic Encephalopathy	15.1%
168	Basal Ganglia Diseases	15.1%
169	Brain Damage, Chronic	15.1%
170	Cerebellar Diseases	15.1%
171	Encephalitis	15.1%
172	Encephalomalacia	15.1%
173	Epilepsy	15.1%
174	Hydrocephalus	15.1%
175	Congenital Hydrocephalus	15.1%
176	Hypothalamic Diseases	15.1%
177	Thalamic Diseases	15.1%
178	Intracranial Hypertension	15.1%
179	Aura	15.1%
180	Leukoencephalopathy	15.1%
181	Neuroaxonal Dystrophies	15.1%
182	Headache Disorders	15.1%
183	Intracranial Hypotension	15.1%
184	Brain Edema	15.1%
185	Brain Hypoxia	15.1%
186	Aqueductal Stenosis	15.1%
187	Brain Injuries	15.1%
188	Leukoencephalopathy, Progressive Multifocal	15%
189	Colitis, Ischemic	15%
190	Brain Neoplasms	15%
191	Hypotension, Orthostatic	14.8%
192	Post-Exercise Hypotension	14.8%
193	Ophthalmoplegic Migraine	14.7%
194	Hematoma, Subdural, Intracranial	14.6%
195	Hematoma, Subdural, Chronic	14.6%
196	Hematoma, Subdural, Acute	14.6%
197	Cerebellar Neoplasms	14.6%
198	Dystonia Musculorum Deformans	14.4%
199	Myelitis	14.4%
200	Meige Syndrome	14.2%
201	Cerebral Ventriculitis	14.2%
202	Myoclonic Epilepsy	14.2%
203	Epilepsy, Temporal Lobe	14.2%
204	Epilepsy, Rolandic	14.2%
205	Benign Rolandic Epilepsy	14.2%
206	Amyotrophic Lateral Sclerosis	14%
207	Rheumatoid Vasculitis	13.9%
208	Subacute Combined Degeneration	13.8%
209	Spinal Muscular Atrophy	13.8%
210	Progressive Muscular Atrophy	13.8%
211	Scimitar Syndrome	13.6%
212	Prion Diseases	13.5%
213	Brain Death	13.5%
214	Neuroleptic Malignant Syndrome	13.4%
215	Myelinolysis, Central Pontine	13.4%
216	Aneurysm, Dissecting	13.4%
217	Arteriosclerosis	13.4%
218	Embolism	13.4%
219	Erythromelalgia	13.4%
220	Fibromuscular Dysplasia	13.4%
221	Malignant Hypertension	13.4%
222	Raynaud Disease	13.4%
223	Thromboembolism	13.4%
224	Thrombosis	13.4%
225	Essential Hypertension	13.4%
226	Aneurysm, Ruptured	13.4%
227	Iliac Aneurysm	13.4%
228	Pulmonary artery stenosis	13.4%
229	White Coat Hypertension	13.4%
230	Embolus	13.4%
231	May-Thurner Syndrome	13.3%
232	Angina Pectoris	13.3%
233	Fabry Disease	13.1%
234	Brain Diseases, Metabolic	13%
235	Dementia	13%
236	Meningitis	13%
237	Movement Disorders	13%
238	Pachymeningitis	13%
239	Spinal Cord Diseases	13%
240	Poliomyelitis	13%
241	MPTP Poisoning	13%
242	Limbic Encephalitis	12.9%
243	Anterior Spinal Artery Syndrome	12.8%
244	Motor Neuron Disease	12.7%
245	Amblyopia	12.6%
246	Embolism, Amniotic Fluid	12.6%
247	CREST Syndrome	12.6%
248	Restless Legs Syndrome	12.5%
249	Creutzfeldt-Jakob disease	12.4%
250	Pituitary Adenoma	12.3%
251	Pituitary Neoplasms	12.3%
252	Juvenile Myoclonic Epilepsy	12.2%
253	Myoclonic Epilepsies, Progressive	12.2%
254	Behcet Syndrome	12.1%
255	Cranial nerve diseases	12.1%
256	Demyelinating Diseases	12.1%
257	Demyelination	12.1%
258	Neuromuscular Diseases	12.1%
259	Chronobiology Disorders	12.1%
260	Spinal Cord Injuries	12.1%
261	Lafora Disease	12.1%
262	Unverricht-Lundborg Syndrome	12.1%
263	Hepatolenticular Degeneration	12%
264	Asterixis	11.8%
265	Ballismus	11.8%
266	Presenile dementia	11.7%
267	Senile dementia	11.7%
268	Cerebrovascular Disorders	11.6%
269	Retinal Artery Occlusion	11.6%
270	Hypertensive Retinopathy	11.6%
271	Canavan Disease	11.6%
272	Cerebrovascular Insufficiency	11.6%
273	Alexander Disease	11.6%
274	Heart Diseases	11.6%
275	Anterior Compartment Syndrome	11.5%
276	Gastric Antral Vascular Ectasia	11.5%
277	Abdominal Compartment Syndrome	11.5%
278	Central Nervous System Infection	11.4%
279	Varicose Ulcer	11.4%
280	Primary Graft Dysfunction	11.4%
281	Vasculitis, Central Nervous System	11.4%
282	Coronary Occlusion	11.4%
283	Microvascular Angina	11.4%
284	Coronary Stenosis	11.4%
285	ST segment elevation myocardial infarction	11.4%
286	Opsoclonus-Myoclonus Syndrome	11.1%
287	Amnesia, Transient Global	10.9%
288	Friedreich Ataxia	10.9%
289	Meningitis, Bacterial	10.8%
290	Meningitis, Fungal	10.8%
291	Chronic Fatigue Syndrome	10.8%
292	Brain Injuries, Diffuse	10.7%
293	Traumatic Brain Injury	10.7%
294	Cerebellar Ataxia	10.7%
295	Supratentorial Neoplasms	10.7%
296	Toxoplasmosis, Cerebral	10.7%
297	Trauma, Nervous System	10.7%
298	Autonomic Dysreflexia	10.6%
299	Complex Regional Pain Syndromes	10.6%
300	Cerebral Palsy	10.6%
301	Epilepsies, Partial	10.6%
302	Epilepsy, Generalized	10.6%
303	Pseudotumor Cerebri	10.6%
304	Hypertensive Encephalopathy	10.6%
305	Simple Partial Seizures	10.6%
306	Epilepsy, Reflex	10.6%
307	Headache Disorders, Primary	10.6%
308	Headache Disorders, Secondary	10.6%
309	Medication overuse headache	10.6%
310	Nervous System Neoplasms	10.4%
311	Neurologic Manifestations	10.4%
312	Neurotoxicity Syndromes	10.4%
313	Cryoglobulinemia	10.3%
314	Paraneoplastic Cerebellar Degeneration	10.3%
315	Persistent Vegetative State	10.3%
316	Vasculitis	10.2%
317	Antiphospholipid Syndrome	10.2%
318	Mesenteric Vascular Occlusion	10.1%
319	Dyskinesia, Drug-Induced	10.1%
320	Diabetic Retinopathy	10.1%
321	Livedo Reticularis	10%
322	Arteriosclerosis Obliterans	10%
323	Atherosclerosis	10%
324	Air Embolism	10%
325	Renal hypertension	10%
326	Renal Artery Obstruction	10%
327	Renal Artery Stenosis	10%
328	Spinal Cord Neoplasms	10%
329	Venous Thrombosis	10%
330	Deep Vein Thrombosis	10%
331	Venous Thromboembolism	10%
332	Hemangioma, Cavernous	10%
333	Shock, Cardiogenic	10%
334	Pregnancy Complications, Cardiovascular	10%
335	Cardiovascular Abnormalities	10%
336	Scurvy	9.9%
337	Angina, Unstable	9.9%
338	Angioedemas, Hereditary	9.8%
339	Multiple Myeloma	9.7%
340	Causalgia	9.5%
341	Tuberculosis, Meningeal	9.5%
342	Akathisia, Drug-Induced	9.4%
343	Coronary Restenosis	9.4%
344	Peripheral Nerve Injuries	9.4%
345	Pituitary Diseases	9.3%
346	Sleep Wake Disorders	9.3%
347	Olfactory Nerve Injuries	9.2%
348	Kluver-Bucy Syndrome	9%
349	Adrenoleukodystrophy	9%
350	Ischemic contracture	8.9%
351	Tricuspid Atresia	8.9%
352	Arrhythmogenic Right Ventricular Dysplasia	8.9%
353	Diabetic Foot	8.8%
354	Lupus Erythematosus, Systemic	8.8%
355	Overlap syndrome	8.8%
356	Addison Disease	8.7%
357	Pemphigus	8.7%
358	Autoimmune thyroiditis	8.7%
359	Primary Adrenal Insufficiency	8.7%
360	Intermittent Claudication	8.7%
361	Pulmonary Embolism	8.7%
362	Autoimmune hepatitis	8.7%
363	Diffuse Axonal Injury	8.6%
364	Brain Stem Neoplasms	8.6%
365	Progressive bulbar palsy	8.6%
366	Bulbar palsy	8.6%
367	Mitochondrial Encephalomyopathies	8.6%
368	Subacute Sclerosing Panencephalitis	8.6%
369	No-Reflow Phenomenon	8.6%
370	Waldenstrom Macroglobulinemia	8.5%
371	Sleep Disorders, Circadian Rhythm	8.4%
372	Scrapie	8.4%
373	Central Cord Syndrome	8.4%
374	Arachnoiditis	8.4%
375	Aseptic Meningitis	8.4%
376	Syringomyelia	8.4%
377	Essential Tremor	8.4%
378	Familial Tremor	8.4%
379	Pneumorrhachis	8.4%
380	Writer's Cramp	8.4%
381	Brain Concussion	8.3%
382	Hereditary Angioedema Type III	8.3%
383	Hereditary Angioedema Types I and II	8.3%
384	Post-Traumatic Headache	8.3%
385	Tension Headache	8.3%
386	Epilepsy, Complex Partial	8.3%
387	Migraine Disorders	8.3%
388	Abdominal Migraine	8.3%
389	Status Migrainosus	8.3%
390	Cervicogenic Headache	8.3%
391	Facial Nerve Injuries	8.3%
392	Autoimmune Lymphoproliferative Syndrome	8.3%
393	Chorea	8.3%
394	Botulism	8.2%
395	Central Nervous System Cysts	8.2%
396	Angina Pectoris, Variant	8.2%
397	Alice in Wonderland Syndrome	8%
398	Frontotemporal dementia	8%
399	Purpura, Hyperglobulinemic	7.9%
400	Reye Syndrome	7.9%
401	Hepatic Encephalopathy	7.9%
402	Dural Arteriovenous Fistula	7.8%
403	Auditory Perceptual Disorders	7.8%
404	Brain Contusion	7.7%
405	Aortic Valve Stenosis	7.7%
406	Cardiomyopathy, Dilated	7.7%
407	Pulmonary Valve Stenosis	7.7%
408	Latent Autoimmune Diabetes in Adults	7.6%
409	Kernicterus	7.6%
410	Reflex Sympathetic Dystrophy	7.6%
411	Nocturnal Myoclonus Syndrome	7.6%
412	AIDS Dementia Complex	7.6%
413	Dermatitis Herpetiformis	7.6%
414	Choroid Plexus Papilloma	7.6%
415	Refsum Disease	7.6%
416	Bacterial Endocarditis	7.5%
417	Hypertension, Renovascular	7.4%
418	Torticollis	7.4%
419	Horner Syndrome	7.4%
420	Dysautonomia	7.3%
421	Vagus Nerve Disorder	7.3%
422	Glossopharyngeal Neuralgia	7.3%
423	Abducens Nerve Diseases	7.3%
424	Heavy Metal Poisoning, Nervous System	7.3%
425	Neuromuscular Junction Diseases	7.3%
426	Tauopathies	7.3%
427	Trochlear Nerve Diseases	7.3%
428	Peripheral Nervous System Diseases	7.3%
429	Meningitis, Cryptococcal	7.3%
430	Meningitis, Listeria	7.3%
431	Meningitis, Haemophilus	7.3%
432	Meningitis, Pneumococcal	7.3%
433	Charcot-Marie-Tooth Disease	7.2%
434	Central Nervous System Fungal Infections	7.2%
435	Conus Medullaris Syndrome	7.2%
436	Empty Sella Syndrome	7.2%
437	Hepatic Vein Thrombosis	7.2%
438	Hyperpituitarism	7.2%
439	Hypopituitarism	7.2%
440	Hypophysitis	7.2%
441	Budd-Chiari Syndrome	7.2%
442	Cluster Headache	7.2%
443	Migraine with Aura	7.2%
444	Familial Hemiplegic Migraine	7.2%
445	Chronic Paroxysmal Hemicrania	7.2%
446	SUNCT Syndrome	7.2%
447	Paroxysmal Hemicrania	7.2%
448	Pulmonary Infarction	7.1%
449	West Nile Fever	7.1%
450	Brain Diseases, Metabolic, Inborn	7%
451	Tuberous Sclerosis	7%
452	Rheumatoid Arthritis	6.8%
453	Juvenile arthritis	6.8%
454	Cardiac Tamponade	6.8%
455	Endocarditis	6.8%
456	Cardiac Arrest	6.8%
457	Heart failure	6.8%
458	Pericardial effusion	6.8%
459	Pericarditis	6.8%
460	Pneumopericardium	6.8%
461	Cor pulmonale	6.8%
462	Ventricular Outflow Obstruction	6.8%
463	Ventricular Dysfunction	6.8%
464	Cardiomyopathies	6.8%
465	Pleuropericarditis	6.8%
466	Graves Disease	6.7%
467	Ophthalmoplegia	6.7%
468	External Ophthalmoplegia	6.7%
469	Pseudoxanthoma Elasticum	6.7%
470	Heart Block	6.7%
471	Tachycardia	6.7%
472	Tachyarrhythmia	6.7%
473	Jet Lag Syndrome	6.7%
474	Aortic coarctation	6.7%
475	Cor Triatriatum	6.7%
476	Coronary Vessel Anomalies	6.7%
477	Patent ductus arteriosus	6.7%
478	Ebstein Anomaly	6.7%
479	Heart Septal Defects	6.7%
480	Tetralogy of Fallot	6.7%
481	Transposition of Great Vessels	6.7%
482	Hypoplastic Left Heart Syndrome	6.7%
483	Anti-Glomerular Basement Membrane Disease	6.7%
484	Autoimmune thrombocytopenia	6.6%
485	Immune thrombocytopenic purpura	6.6%
486	Brachial Plexus Neuritis	6.6%
487	Neuralgic Amyotrophy	6.6%
488	Acrodynia	6.6%
489	Tardive Dyskinesia	6.6%
490	Myopathy	6.5%
491	Optic Neuropathy	6.5%
492	Central Nervous System Bacterial Infections	6.4%
493	Facial Nerve Diseases	6.3%
494	Craniocerebral Trauma	6.3%
495	Parasomnia	6.3%
496	Dyssomnias	6.3%
497	Wernicke Encephalopathy	6.3%
498	Vestibulocochlear Nerve Diseases	6.3%
499	Decerebrate State	6.3%
500	Hemiparesis	6.3%
501	Hydranencephaly	6.3%
502	Meningism	6.3%
503	Neural Tube Defects	6.3%
504	Paresis	6.3%
505	Seizures	6.3%
506	Sensation Disorders	6.3%
507	Tethered Cord Syndrome	6.3%
508	Central Nervous System Neoplasms	6.3%
509	Complex partial seizures	6.3%
510	Iniencephaly	6.3%
511	Craniorachischisis	6.3%
512	Exencephaly	6.3%
513	Monoparesis	6.3%
514	Septo-Optic Dysplasia	6.3%
515	Cortical Dysplasia	6.3%
516	Neurogenic Inflammation	6.3%
517	Gait Disorders, Neurologic	6.3%
518	Neuromuscular Manifestations	6.3%
519	Malformations of Cortical Development	6.3%
520	Sweating, Gustatory	6.2%
521	Auriculotemporal Syndrome	6.2%
522	Hypertrophic Cardiomyopathy	6.2%
523	Hypertrophic obstructive cardiomyopathy	6.2%
524	Hyperprolactinemia	6.2%
525	Tarsal Tunnel Syndrome	6.1%
526	Cauda Equina Syndrome	6.1%
527	Pick Disease of the Brain	6.1%
528	Vocal Cord Paralysis	6.1%
529	Myotonic Dystrophy	6.1%
530	Coma, Post-Head Injury	6%
531	Dextrocardia	5.9%
532	Long QT Syndrome	5.9%
533	Myotonia Congenita	5.9%
534	Sick Sinus Syndrome	5.9%
535	Cerebrospinal Fluid Otorrhea	5.9%
536	Cerebrospinal Fluid Rhinorrhea	5.9%
537	Gait Ataxia	5.9%
538	Cardiac Output, High	5.9%
539	Myocardial Stunning	5.9%
540	Low Cardiac Output Syndrome	5.9%
541	Optic Nerve Glioma	5.8%
542	Cardiomegaly	5.8%
543	Postpericardiotomy Syndrome	5.8%
544	Cardiac Hypertrophy	5.8%
545	Hypersensitivity	5.8%
546	Immunologic Deficiency Syndromes	5.8%
547	Immunoproliferative Disorders	5.8%
548	Immune reconstitution syndrome	5.8%
549	Immune Reconstitution Inflammatory Syndrome	5.8%
550	Rheumatic Heart Disease	5.8%
551	Supravalvular aortic stenosis	5.7%
552	Lown-Ganong-Levine Syndrome	5.7%
553	Kearns-Sayre syndrome	5.6%
554	Pupil Disorders	5.6%
555	Neurobehavioral Manifestations	5.6%
556	Paraneoplastic Encephalomyelitis	5.5%
557	Vertigo	5.5%
558	Alcohol-Induced Disorders, Nervous System	5.5%
559	Alcohol Withdrawal Seizures	5.4%
560	Acromegaly	5.4%
561	Carpal Tunnel Syndrome	5.4%
562	neurofibroma	5.4%
563	Sciatica	5.3%
564	Akathisia	5.3%
565	Restlessness	5.3%
566	Psychomotor Agitation	5.3%
567	Tuberculosis, Central Nervous System	5.2%
568	Alstrom Syndrome	5.2%
569	Neuritis	5%
570	Polyneuritis	5%
571	Radiculitis	5%
572	Polyneuropathy	5%
573	Mononeuritis	5%
574	Mononeuropathies	5%
575	Brachial Plexus Neuropathies	5%
576	Radiculopathy	5%
577	Mononeuropathy Multiplex	5%
578	Nerve Root Compression	5%
579	Transfusion Reaction	5%
580	Hypotensive Transfusion Reaction	5%
581	Adams-Stokes Syndrome	5%
582	Atrioventricular Block	5%
583	Bundle-Branch Block	5%
584	Atrial Premature Complexes	5%
585	Sinoatrial Block	5%
586	Tachycardia, Paroxysmal	5%
587	Supraventricular tachycardia	5%
588	Tachycardia, Ventricular	5%
589	Wolff-Parkinson-White Syndrome	5%
590	Tachycardia, Reciprocating	5%
591	Aortopulmonary Septal Defect	4.9%
592	Double Outlet Right Ventricle	4.9%
593	Endocardial Cushion Defects	4.9%
594	Myocardial bridging	4.9%
595	Aorticopulmonary Septal Defect	4.9%
596	Voice Disorders	4.9%
597	Voice Disturbance	4.9%
598	Cubital Tunnel Syndrome	4.9%
599	Gait Apraxia	4.9%
600	Smith-Magenis syndrome	4.9%
601	Noonan Syndrome	4.9%
602	Subacute Bacterial Endocarditis	4.6%
603	Neuroaspergillosis	4.6%
604	Menkes Kinky Hair Syndrome	4.6%
605	Brain Diseases	4.5%
606	Marfan Syndrome	4.5%
607	Galactosemias	4.5%
608	Urea Cycle Disorders, Inborn	4.5%
609	Tyrosinemias	4.5%
610	Aortic Valve Insufficiency	4.5%
611	Restrictive cardiomyopathy	4.5%
612	Endocardial Fibroelastosis	4.5%
613	Heart Rupture, Post-Infarction	4.5%
614	Mitral Valve Insufficiency	4.5%
615	Mitral Valve Stenosis	4.5%
616	Myocarditis	4.5%
617	Pericarditis, Constrictive	4.5%
618	Pulmonary Valve Insufficiency	4.5%
619	Tricuspid Valve Insufficiency	4.5%
620	Tricuspid Valve Stenosis	4.5%
621	Ventricular Dysfunction, Left	4.5%
622	Right Ventricular Dysfunction	4.5%
623	Endomyocardial Fibrosis	4.5%
624	Carditis	4.5%
625	Heart Failure, Systolic	4.5%
626	Heart Failure, Diastolic	4.5%
627	Felty Syndrome	4.4%
628	Williams Syndrome	4.4%
629	Lupus Nephritis	4.4%
630	Carcinoid Heart Disease	4.4%
631	Romano-Ward Syndrome	4.4%
632	Amyloid Neuropathies, Familial	4.4%
633	Nelson Syndrome	4.4%
634	Myositis	4.3%
635	Optic Atrophy	4.3%
636	Optic Neuritis	4.3%
637	Papilledema	4.3%
638	Strabismus	4.3%
639	Tolosa-Hunt Syndrome	4.3%
640	Isaacs syndrome	4.3%
641	Arsenic Poisoning	4.3%
642	Myotonic Disorders	4.3%
643	Myasthenic Syndromes, Congenital	4.3%
644	Reflex, Abnormal	4.3%
645	Hyporeflexia	4.3%
646	Hyperreflexia	4.3%
647	Diabetic Neuropathies	4.3%
648	Facial Injuries	4.3%
649	Facial Neuralgia	4.3%
650	Diabetic Amyotrophy	4.3%
651	Diabetic Autonomic Neuropathy	4.3%
652	Sleep Talking	4.3%
653	Manganese Poisoning	4.3%
654	Sleep Disorders, Intrinsic	4.3%
655	Orthostatic intolerance	4.3%
656	Prolactinoma	4.3%
657	Growth Hormone-Secreting Pituitary Adenoma	4.3%
658	Anosmia	4.3%
659	Ataxia	4.3%
660	Athetosis	4.3%
661	Catalepsy	4.3%
662	Dystonia	4.3%
663	Hemiplegia	4.3%
664	Locked-In Syndrome	4.3%
665	Meningeal Neoplasms	4.3%
666	Meningomyelocele	4.3%
667	Muscle Hypertonia	4.3%
668	Muscle hypotonia	4.3%
669	Myoclonus	4.3%
670	Myotonia	4.3%
671	Neuralgia	4.3%
672	Paraplegia	4.3%
673	Pseudobulbar Palsy	4.3%
674	Quadriplegia	4.3%
675	Spasm	4.3%
676	Spastic Paraplegia	4.3%
677	Status Epilepticus	4.3%
678	Taste Disorders	4.3%
679	Tremor	4.3%
680	Spina Bifida	4.3%
681	Monoplegia	4.3%
682	Hypokinesia	4.3%
683	Paraparesis	4.3%
684	Bradykinesia	4.3%
685	Waxy flexibility	4.3%
686	Action Tremor	4.3%
687	Resting Tremor	4.3%
688	Dysosmia	4.3%
689	Quadriparesis	4.3%
690	Mercury Poisoning, Nervous System	4.3%
691	Olfaction Disorders	4.3%
692	Myokymia	4.3%
693	Lead Poisoning, Nervous System	4.3%
694	Vestibular Neuronitis	4.3%
695	Somatosensory Disorders	4.3%
696	Neuropathic pain	4.3%
697	Hyperkinesia	4.3%
698	Intention tremor	4.3%
699	Classical Lissencephalies and Subcortical Band Heterotopias	4.3%
700	Glomerulonephritis, Membranoproliferative	4.2%
701	Acoustic Neuroma	4.2%
702	Pseudorabies	4.2%
703	Homocystinuria	4.1%
704	Tachycardia, Atrioventricular Nodal Reentry	4.1%
705	Tachycardia, Ectopic Atrial	4.1%
706	Tachycardia, Ectopic Junctional	4.1%
707	Sinus Tachycardia	4.1%
708	Torsades de Pointes	4.1%
709	Accelerated Idioventricular Rhythm	4.1%
710	Truncus Arteriosus, Persistent	4.1%
711	Leigh Disease	4.1%
712	POEMS Syndrome	4.1%
713	Neurosyphilis	4%
714	Waterhouse-Friderichsen Syndrome	4%
715	Alexia	3.9%
716	Dyslexia	3.9%
717	Sciatic Neuropathy	3.9%
718	Ulnar Neuropathies	3.9%
719	Lesion of Sciatic Nerve	3.9%
720	Ulnar Neuritis	3.9%
721	Radial nerve compression	3.9%
722	Radial Tunnel Syndrome	3.9%
723	Peroneal Neuropathies	3.9%
724	Radial Neuropathy	3.9%
725	Median Neuropathy	3.9%
726	Sciatic Nerve Palsy	3.9%
727	Femoral Neuropathy	3.9%
728	Tibial Neuropathy	3.9%
729	Ulnar Nerve Palsy	3.9%
730	Postural Orthostatic Tachycardia Syndrome	3.9%
731	Radial nerve palsy	3.9%
732	Vision Disorders	3.8%
733	Metamorphopsia	3.8%
734	Visual Impairment	3.8%
735	Fibromyalgia	3.8%
736	Medial Tibial Stress Syndrome	3.8%
737	Sinus Arrhythmia	3.8%
738	Atrial Fibrillation	3.8%
739	Atrial Flutter	3.8%
740	Edema, Cardiac	3.8%
741	Ventricular Fibrillation	3.8%
742	Ventricular Flutter	3.8%
743	Parasystole	3.8%
744	Paroxysmal atrial fibrillation	3.8%
745	Bradycardia	3.8%
746	Diabetic Cardiomyopathies	3.8%
747	Cardiomyopathy, Alcoholic	3.8%
748	Ectopia Cordis	3.8%
749	Sudden Cardiac Death	3.8%
750	Left Ventricular Hypertrophy	3.8%
751	Right Ventricular Hypertrophy	3.8%
752	Single umbilical artery	3.8%
753	Chagas Cardiomyopathy	3.8%
754	Facial Hemiatrophy	3.8%
755	Melkersson-Rosenthal Syndrome	3.8%
756	Mitochondrial Myopathies	3.8%
757	Anisocoria	3.8%
758	Confusion	3.8%
759	Facial paralysis	3.8%
760	Lethargy	3.8%
761	Memory Disorders	3.8%
762	Muscle Cramp	3.8%
763	Perceptual Disorders	3.8%
764	Psychomotor Disorders	3.8%
765	Tonic Pupil	3.8%
766	Eosinophilia-Myalgia Syndrome	3.8%
767	Anhedonia	3.8%
768	Disorientation	3.8%
769	Facial Paresis	3.8%
770	Memory Loss	3.8%
771	Hemisensory Neglect	3.8%
772	Dysacusis	3.8%
773	Sleep Bruxism	3.8%
774	Toxoplasmosis, Congenital	3.8%
775	Anencephaly	3.7%
776	Meningocele	3.7%
777	Muscular Atrophy	3.7%
778	Respiratory Paralysis	3.7%
779	Encephalocele	3.7%
780	Neurofibrosarcoma	3.7%
781	Malaria, Cerebral	3.7%
782	Tetany	3.7%
783	Neurocysticercosis	3.7%
784	Sicca Syndrome	3.6%
785	Sjogren's Syndrome	3.6%
786	Lyme Neuroborreliosis	3.6%
787	Optic Atrophy, Hereditary, Leber	3.6%
788	Carbamoyl-Phosphate Synthase I Deficiency Disease	3.5%
789	Duane Retraction Syndrome	3.4%
790	Immune Complex Diseases	3.4%
791	Latex allergy	3.4%
792	Consciousness Disorders	3.4%
793	Mental Retardation	3.4%
794	Muscle Weakness	3.4%
795	Depressed Level of Consciousness	3.4%
796	Mental deficiency	3.4%
797	Intellectual Disability	3.4%
798	Mobius Syndrome	3.4%
799	Bell Palsy	3.4%
800	Thrombocytopenic purpura	3.4%
801	Catatonia	3.4%
802	Herpes Zoster Oticus	3.4%
803	Familial Periodic Paralysis	3.3%
804	Aortic Valve Prolapse	3.3%
805	Aphonia	3.3%
806	Dyspnea, Paroxysmal	3.3%
807	Esotropia	3.3%
808	Exotropia	3.3%
809	Sleep Apnea Syndromes	3.3%
810	Sleep Deprivation	3.3%
811	Tricuspid Valve Prolapse	3.3%
812	Polymyositis	3.3%
813	Dysphonia	3.3%
814	Takotsubo Cardiomyopathy	3.3%
815	Polyradiculopathy	3.3%
816	Disorders of Excessive Somnolence	3.3%
817	Sleep Initiation and Maintenance Disorders	3.3%
818	Night Terrors	3.3%
819	Somnambulism	3.3%
820	Trigeminal Nerve Disorder	3.3%
821	Transient Insomnia	3.3%
822	Sleep Paralysis	3.3%
823	Chronic Insomnia	3.3%
824	REM Sleep Behavior Disorder	3.3%
825	Hypersomnia	3.3%
826	Dermal Sinus	3.3%
827	Dysgeusia	3.3%
828	Formication	3.3%
829	Hyperalgesia	3.3%
830	Hyperesthesia	3.3%
831	Hypesthesia	3.3%
832	Language Disorders	3.3%
833	Numbness	3.3%
834	Paresthesia	3.3%
835	Paraparesis, Spastic	3.3%
836	Spina Bifida Cystica	3.3%
837	Trismus	3.3%
838	Spina Bifida Occulta	3.3%
839	Epilepsia Partialis Continua	3.3%
840	Hypogeusia	3.3%
841	Meningeal Carcinomatosis	3.3%
842	Brown-Sequard Syndrome	3.3%
843	Lissencephaly	3.3%
844	Polymicrogyria	3.3%
845	Pachygyria	3.3%
846	Schizencephaly	3.3%
847	Lockjaw	3.3%
848	Allodynia	3.3%
849	Lead Poisoning, Nervous System, Childhood	3.3%
850	Lead Poisoning, Nervous System, Adult	3.3%
851	Periventricular Nodular Heterotopia	3.3%
852	Ageusia	3.3%
853	Zellweger Syndrome	3.3%
854	Glycogen storage disease type II	3.2%
855	Myalgia	3%
856	Environmental Illness	3%
857	Eye Injuries	3%
858	Neuronal Ceroid-Lipofuscinoses	3%
859	Primary amyloidosis	3%
860	Monoclonal Gammopathy of Undetermined Significance	3%
861	Muscular Dystrophy	2.9%
862	Congenital nystagmus	2.9%
863	Orbital Myositis	2.9%
864	Lymphoproliferative Disorders	2.9%
865	Diplopia	2.9%
866	Muscle Rigidity	2.9%
867	Muscle Spasticity	2.9%
868	Scotoma	2.9%
869	Photophobia	2.9%
870	Cogwheel Rigidity	2.9%
871	Hemifacial Spasm	2.9%
872	Amaurosis	2.9%
873	Blindness	2.9%
874	Nuchal Rigidity	2.9%
875	Pyomyositis	2.9%
876	Agnosia	2.9%
877	Apraxias	2.9%
878	Hallucinations	2.9%
879	Hemianopsia	2.9%
880	Paraproteinemias	2.9%
881	Hyperacusis	2.9%
882	Tinnitus	2.9%
883	Visual Agnosia	2.9%
884	Anosognosia	2.9%
885	Wernicke-Korsakoff Syndrome	2.9%
886	Phonophobia	2.9%
887	Hearing Loss	2.9%
888	Turner Syndrome	2.9%
889	Sarcopenia	2.9%
890	Lymphopenia	2.9%
891	Sinus Arrest, Cardiac	2.8%
892	Sleep Apnea, Obstructive	2.8%
893	Sleep Apnea, Central	2.8%
894	Narcolepsy	2.8%
895	Trigeminal Neuralgia	2.8%
896	Kleine-Levin Syndrome	2.8%
897	Agraphia	2.8%
898	Anomia	2.8%
899	Cluttering	2.8%
900	Language Development Disorders	2.8%
901	Speech Disorders	2.8%
902	Syncope	2.8%
903	Stupor	2.8%
904	Dysgraphia	2.8%
905	Presyncope	2.8%
906	Dyslalia	2.8%
907	Gaucher Disease	2.8%
908	Aicardi's syndrome	2.8%
909	Hoarseness	2.7%
910	Cockayne Syndrome	2.7%
911	Alcohol Withdrawal Delirium	2.7%
912	Asthma, Aspirin-Induced	2.7%
913	Amnesia	2.6%
914	Delirium	2.6%
915	Dissociative Amnesia	2.6%
916	Color blindness	2.6%
917	Global Amnesia	2.6%
918	Cri-du-Chat Syndrome	2.6%
919	Down Syndrome	2.6%
920	Trisomy 21	2.6%
921	Cataplexy	2.6%
922	Aphasia	2.6%
923	Articulation Disorders	2.6%
924	Echolalia	2.6%
925	Stuttering	2.6%
926	Dysphasia	2.6%
927	Meningioma	2.6%
928	Tay-Sachs Disease	2.6%
929	Serum Sickness	2.6%
930	Microcephaly	2.6%
931	Macrocephaly	2.6%
932	Hypokalemic periodic paralysis	2.6%
933	Porencephaly	2.6%
934	Hypergammaglobulinemia	2.6%
935	Agammaglobulinemia	2.5%
936	HIV Infections	2.5%
937	Transfusion-Related Acute Lung Injury	2.5%
938	Eye Burns	2.5%
939	Holoprosencephaly	2.5%
940	Welander Distal Myopathy	2.5%
941	Amaurosis Fugax	2.5%
942	Blindness, Cortical	2.5%
943	Dyscalculia	2.5%
944	Rett Syndrome	2.5%
945	Dysarthria	2.5%
946	Deafness	2.5%
947	Hearing Loss, Sudden	2.5%
948	Gerstmann Syndrome	2.5%
949	Hearing Loss, Bilateral	2.5%
950	Hearing Loss, High-Frequency	2.5%
951	Hearing Loss, Mixed Conductive-Sensorineural	2.5%
952	Prosopagnosia	2.5%
953	Apraxia, Ideomotor	2.5%
954	Charles Bonnet Syndrome	2.5%
955	Hearing Loss, Unilateral	2.5%
956	Complete Hearing Loss	2.5%
957	Alien Hand Syndrome	2.5%
958	Deaf Mutism	2.5%
959	Niemann-Pick Disease, Type C	2.5%
960	Kartagener Syndrome	2.4%
961	Prader-Willi Syndrome	2.3%
962	Phantom pain	2.3%
963	Phantom Limb Pain	2.3%
964	Mutism	2.3%
965	Selective Mutism	2.3%
966	Dermatomyositis	2.2%
967	Corneal Scar	2.2%
968	anaphylaxis	2.2%
969	Food Allergy	2.2%
970	Anaphylactic shock	2.2%
971	Muscular Dystrophy, Duchenne	2.2%
972	Retrograde amnesia	2.2%
973	Amnesia, Anterograde	2.2%
974	Alexia, Pure	2.2%
975	Corneal Perforation	2%
976	Sezary Syndrome	2%
977	Fragile X Syndrome	2%
978	Respiratory Hypersensitivity	2%
979	Rubinstein-Taybi Syndrome	1.9%
980	Sick Building Syndrome	1.9%
981	Multiple Chemical Sensitivity	1.9%
982	Plasmacytoma	1.9%
983	Tumor Lysis Syndrome	1.9%
984	Urticaria	1.9%
985	HTLV-I Infections	1.9%
986	Job Syndrome	1.9%
987	Lymphoma	1.7%
988	Mastocytosis	1.7%
989	Drug Eruptions	1.7%
990	Chronic granulomatous disease	1.7%
991	Heavy Chain Disease	1.7%
992	Milk Allergy	1.7%
993	Schnitzler Syndrome	1.7%
994	Wheat Hypersensitivity	1.7%
995	Hydrops Fetalis	1.7%
996	Dermatitis, Allergic Contact	1.7%
997	HIV Seropositivity	1.7%
998	Mucopolysaccharidosis II	1.5%
999	Acquired Immunodeficiency Syndrome	1.5%
1000	AIDS related complex	1.5%
1001	Infectious Mononucleosis	1.5%
1002	Mastocytosis, Systemic	1.4%
1003	AIDS-Related Opportunistic Infections	1.3%
1004	Dermatitis, Atopic	1.3%
1005	HIV Wasting Syndrome	1.3%
1006	AIDS-Associated Nephropathy	1.3%
1007	Hodgkin Disease	1.2%
1008	Leukemia, Plasma Cell	1.2%
1009	Lymphoma, Non-Hodgkin	1.2%
1010	Leukemia, T-Cell	1.2%
1011	Acute Generalized Exanthematous Pustulosis	1.2%
1012	Leukemia, B-Cell	1.2%
1013	Wiskott-Aldrich Syndrome	1.2%
1014	HIV-Associated Lipodystrophy Syndrome	1.2%
1015	Asthma	1.1%
1016	Composite Lymphoma	1.1%
1017	Erythema Nodosum	1.1%
1018	Dermatitis, Photoallergic	1.1%
1019	Lymphangioleiomyomatosis	1.1%
1020	Asthma, Exercise-Induced	1%
1021	Status Asthmaticus	1%
1022	Lymphoma, Follicular	1%
1023	T-Cell Lymphoma	1%
1024	Mantle cell lymphoma	1%
1025	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	1%
1026	Leukemia, Large Granular Lymphocytic	1%
1027	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	1%
1028	Aspergillosis, Allergic Bronchopulmonary	1%
1029	Asthma, Occupational	0.9%
1030	Farmer's Lung	0.9%
1031	Lymphoma, T-Cell, Cutaneous	0.9%
1032	Lymphoma, AIDS-Related	0.9%
1033	Enteropathy-Associated T-Cell Lymphoma	0.9%
1034	Primary Effusion Lymphoma	0.9%
1035	Hay fever	0.9%
1036	Rhinitis, Allergic, Perennial	0.9%
1037	Toxic Epidermal Necrolysis	0.9%
1038	Stevens-Johnson Syndrome	0.9%
1039	Mycosis Fungoides	0.9%
1040	Lymphomatoid Papulosis	0.9%
1041	Plasmablastic lymphoma	0.9%
1042	Lymphomatoid Granulomatosis	0.8%
1043	Burkitt Lymphoma	0.7%

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